Page last updated: 2024-08-17

trichloroethylene and Disease Models, Animal

trichloroethylene has been researched along with Disease Models, Animal in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.70)18.7374
1990's5 (18.52)18.2507
2000's7 (25.93)29.6817
2010's9 (33.33)24.3611
2020's5 (18.52)2.80

Authors

AuthorsStudies
Dai, YY; Huang, LP; Huang, M; Jiang, W; Wang, F; Ye, LP; Zhu, QX1
Dai, Y; Wang, G; Xu, Q; Zhang, J; Zhu, Q1
Deng, LH; Li, N; Shen, T; Xu, QY; Yang, Y; Zhang, JX; Zhang, Y; Zhu, QX1
Huang, M; Jiang, W; Wang, X; Xie, H; Yang, L; Yang, Y; Zhang, J; Zhu, Q1
Dai, Y; Huang, M; Jiang, W; Li, B; Shen, T; Wang, X; Wu, C; Yang, X; Yu, Y; Zhu, Q1
Chen, S; Li, N; Shen, T; Wang, H; Xie, H; Yang, L; Zhang, J; Zhu, QX1
Lynch, RM; Perry, A; Rusyn, I; Threadgill, DW1
Joshi, N; Kassel, KM; Kopec, AK; Luyendyk, JP; Sullivan, BP1
Cline-Fedewa, H; Gershwin, ME; Joshi, N; Kopec, AK; Lash, LH; Leung, PS; Luyendyk, JP; Ray, JL; Williams, KJ1
Bartlett, MG; Bruckner, JV; Liu, Y; Muralidhara, S; White, CA1
Bing, G; Cass, WA; Choi, DY; Gash, DM; Hunter, RL; Kim, HC; Liu, M; Pandya, JD; Sullivan, PG1
Ikemoto, T; Inagaki, N; Kobayashi, R; Nagai, H; Nagase, H; Satoh, M; Seo, M1
Bing, G; Hunter, R; Sauerbeck, A; Sullivan, PG1
Ansari, GA; Khan, MF; Wang, G1
Huang, H; Kamijima, M; Li, L; Li, S; Lin, Y; Nakajima, T; Que, B; Song, X; Tang, X; Wang, H; Yang, X1
Bruckner, JV; Utesch, RC; Weir, FW1
Jones, RM; Kenna, JG1
Abelson, PH1
Barton, HA; Flemming, CD; Lipscomb, JC1
Crofton, KM; Zhao, X1
Gilbert, KM; Griffin, JM; Pumford, NR2
Butterworth, LF; David, DW; Klykken, PC; White, KL1
Lash, LH; Parker, JC; Scott, CS1
Bove, F; Shim, Y; Zeitz, P1
Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1

Reviews

5 review(s) available for trichloroethylene and Disease Models, Animal

ArticleYear
The organ toxicity of inhaled anesthetics.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:6 Suppl

    Topics: Anesthetics, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Disease Models, Animal; Enflurane; Ethers; Halothane; Humans; Isoflurane; Kidney; Liver; Methoxyflurane; Methyl Ethers; Sevoflurane; Trichloroethylene; Vinyl Compounds

1995
Evaluating human variability in chemical risk assessment: hazard identification and dose-response assessment for noncancer oral toxicity of trichloroethylene.
    Toxicology, 1996, Jul-17, Volume: 111, Issue:1-3

    Topics: Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Environmental Illness; Genetic Variation; Hazardous Substances; Humans; Risk Assessment; Trichloroethylene

1996
Assessment of autoimmunity-inducing potential using the brown Norway rat challenge model.
    Toxicology letters, 2000, Mar-15, Volume: 112-113

    Topics: Animals; Anti-Infective Agents, Local; Antibody Formation; Antidotes; Autoimmune Diseases; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin E; Lupus Erythematosus, Systemic; Mercuric Chloride; Penicillamine; Rats; Rats, Inbred BN; Silicone Gels; Solvents; Trichloroethylene

2000
Modes of action of trichloroethylene for kidney tumorigenesis.
    Environmental health perspectives, 2000, Volume: 108 Suppl 2

    Topics: Animals; Biological Assay; Carcinogens, Environmental; Disease Models, Animal; Humans; Incidence; Kidney; Kidney Neoplasms; Mutagens; Trichloroethylene; United States

2000
Drinking water contaminants and adverse pregnancy outcomes: a review.
    Environmental health perspectives, 2002, Volume: 110 Suppl 1

    Topics: Abortion, Spontaneous; Adult; Chromosome Aberrations; Congenital Abnormalities; Disease Models, Animal; Disinfectants; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Solvents; Trichloroethylene; Trihalomethanes; Water Pollutants; Water Supply

2002

Other Studies

22 other study(ies) available for trichloroethylene and Disease Models, Animal

ArticleYear
Terminal complement complex C5b-9 reduced megalin and cubilin-mediated tubule proteins uptake in a mouse model of trichloroethylene hypersensitivity syndrome.
    Toxicology letters, 2019, Dec-15, Volume: 317

    Topics: Animals; Cells, Cultured; Complement Activation; Complement Membrane Attack Complex; Disease Models, Animal; Endocytosis; Female; Hypersensitivity; Kidney Diseases; Kidney Tubules, Proximal; Low Density Lipoprotein Receptor-Related Protein-2; Mice, Inbred BALB C; Protein Transport; Receptors, Cell Surface; Trichloroethylene

2019
Local renal complement activation mediates immune kidney injury by inducing endothelin-1 signalling and inflammation in trichloroethylene-sensitised mice.
    Toxicology letters, 2020, Oct-15, Volume: 333

    Topics: Animals; Complement Activation; Disease Models, Animal; Endothelin-1; Female; Hypersensitivity; Inflammation; Kidney; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; NF-kappa B; Renal Insufficiency; Signal Transduction; Trichloroethylene

2020
Kupffer cell inactivation ameliorates immune liver injury via TNF-α/TNFR1 signal pathway in trichloroethylene sensitized mice.
    Immunopharmacology and immunotoxicology, 2020, Volume: 42, Issue:6

    Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Gadolinium; Kupffer Cells; Liver; Macrophage Activation; Mice, Inbred BALB C; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Trichloroethylene; Tumor Necrosis Factor-alpha

2020
C5b-9 membrane attack complex activated NLRP3 inflammasome mediates renal tubular immune injury in trichloroethylene sensitized mice.
    Ecotoxicology and environmental safety, 2021, Jan-15, Volume: 208

    Topics: Animals; Complement Membrane Attack Complex; Disease Models, Animal; Epithelial Cells; Female; Inflammasomes; Kidney; Kidney Diseases; Lipocalin-2; Mice; Mice, Inbred BALB C; NLR Family, Pyrin Domain-Containing 3 Protein; Solvents; Trichloroethylene

2021
Intracellular complement activation in podocytes aggravates immune kidney injury in trichloroethylene-sensitized mice.
    The Journal of toxicological sciences, 2020, Volume: 45, Issue:11

    Topics: Acute Kidney Injury; Animals; Cathepsin L; Complement Activation; Complement C3; Disease Models, Animal; Female; Glomerular Filtration Rate; Kidney Glomerulus; Mice, Inbred BALB C; Podocytes; Solvents; Trichloroethylene

2020
Bradykinin receptor in immune-mediated renal tubular injury in trichloroethylene-sensitized mice: Impact on NF-κB signaling pathway.
    Journal of immunotoxicology, 2018, Volume: 15, Issue:1

    Topics: Acute Kidney Injury; Animals; Bradykinin Receptor Antagonists; Cytokines; Disease Models, Animal; Female; Humans; Inflammation Mediators; Kallikrein-Kinin System; Kidney; Mice; Mice, Inbred BALB C; NF-kappa B; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Signal Transduction; Trichloroethylene

2018
Long-Term Combinatorial Exposure to Trichloroethylene and Inorganic Arsenic in Genetically Heterogeneous Mice Results in Renal Tubular Damage and Cancer-Associated Molecular Changes.
    G3 (Bethesda, Md.), 2019, 05-07, Volume: 9, Issue:5

    Topics: Animals; Arsenic; Biomarkers; Cell Transformation, Neoplastic; Disease Models, Animal; Drug Synergism; Environmental Exposure; Genetic Predisposition to Disease; Kaplan-Meier Estimate; Kidney Function Tests; Kidney Neoplasms; Kidney Tubules; Male; Mice; Mice, Transgenic; Mutation; Prognosis; Trichloroethylene; Von Hippel-Lindau Tumor Suppressor Protein

2019
Toxicogenomic analysis reveals profibrogenic effects of trichloroethylene in autoimmune-mediated cholangitis in mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 141, Issue:2

    Topics: Animals; Autoimmune Diseases; Chemical and Drug Induced Liver Injury; Cholangitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Early Growth Response Protein 1; Female; Gene Expression Profiling; Gene Expression Regulation; Gene-Environment Interaction; Liver; Liver Cirrhosis, Biliary; Mice, Inbred NOD; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Toxicogenetics; Trichloroethylene

2014
Trichloroethylene Exposure Reduces Liver Injury in a Mouse Model of Primary Biliary Cholangitis.
    Toxicological sciences : an official journal of the Society of Toxicology, 2017, 04-01, Volume: 156, Issue:2

    Topics: Animals; Autoantibodies; Chemical and Drug Induced Liver Injury; Cholangitis; Disease Models, Animal; Female; Gene-Environment Interaction; Hepatitis, Autoimmune; Male; Mice, Transgenic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Trichloroethylene

2017
Presystemic elimination of trichloroethylene in rats following environmentally relevant oral exposures.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:10

    Topics: Animals; Biological Availability; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Liver Neoplasms, Experimental; Male; Mice; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Solid Phase Microextraction; Tissue Distribution; Trichloroethylene; United States

2009
Trichloroethylene induces dopaminergic neurodegeneration in Fisher 344 rats.
    Journal of neurochemistry, 2010, Volume: 112, Issue:3

    Topics: alpha-Synuclein; Animals; Caspase 3; CD11b Antigen; Choline O-Acetyltransferase; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dose-Response Relationship, Drug; Electrochemistry; Encephalitis; Gene Expression Regulation; Male; Mitochondria; Neurodegenerative Diseases; Oxidative Stress; Rats; Rats, Inbred F344; Rotarod Performance Test; Solvents; Substantia Nigra; Trichloroethylene; Tyrosine; Tyrosine 3-Monooxygenase

2010
Enhancement of immediate allergic reactions by trichloroethylene ingestion via drinking water in mice.
    The Journal of toxicological sciences, 2010, Volume: 35, Issue:5

    Topics: Anaphylaxis; Animals; Body Weight; Cell Proliferation; Cytokines; Disease Models, Animal; Drinking; Histamine; Hypersensitivity, Immediate; Immunity, Active; Immunoglobulin E; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Spleen; Trichloroethylene; Water Pollutants, Chemical

2010
Traumatic brain injury and trichloroethylene exposure interact and produce functional, histological, and mitochondrial deficits.
    Experimental neurology, 2012, Volume: 234, Issue:1

    Topics: Animals; Brain Injuries; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Gene Expression Regulation; Male; Mitochondrial Diseases; Motor Activity; Movement Disorders; Oxygen Consumption; Rats; Rats, Inbred F344; Receptors, Dopamine D2; Rotarod Performance Test; Solvents; Trichloroethylene; Tyrosine 3-Monooxygenase

2012
Involvement of lipid peroxidation-derived aldehyde-protein adducts in autoimmunity mediated by trichloroethene.
    Journal of toxicology and environmental health. Part A, 2007, Volume: 70, Issue:23

    Topics: Aldehydes; Animals; Autoantibodies; Autoimmune Diseases; Disease Models, Animal; Female; Lipid Peroxidation; Malondialdehyde; Mice; Microsomes, Liver; Trichloroethylene

2007
Characterization of liver injury associated with hypersensitive skin reactions induced by trichloroethylene in the guinea pig maximization test.
    Journal of occupational health, 2008, Volume: 50, Issue:2

    Topics: Analysis of Variance; Animals; Chemical and Drug Induced Liver Injury; Chi-Square Distribution; Dermatitis, Allergic Contact; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Guinea Pigs; Liver; Trichloroethylene

2008
Development of an animal model of solvent abuse for use in evaluation of extreme trichloroethylene inhalation.
    Toxicology, 1981, Volume: 19, Issue:2

    Topics: Animals; Central Nervous System Depressants; Disease Models, Animal; Enzyme Induction; Ethanol; Fasting; Humans; Liver; Male; Mixed Function Oxygenases; Rats; Reflex; Substance-Related Disorders; Trichloroethylene

1981
Health risk assessment.
    Regulatory toxicology and pharmacology : RTP, 1993, Volume: 17, Issue:2 Pt 1

    Topics: Animals; Carcinogenicity Tests; Carcinogens; Disease Models, Animal; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methylene Chloride; Mice; Neoplasms; Rats; Risk Factors; Tetrachloroethylene; Trichloroethylene; United States; United States Environmental Protection Agency

1993
The ototoxicity of trichloroethylene: extrapolation and relevance of high-concentration, short-duration animal exposure data.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1997, Volume: 38, Issue:1

    Topics: Administration, Inhalation; Analysis of Variance; Animals; Audiometry; Auditory Threshold; Disease Models, Animal; Dose-Response Relationship, Drug; Hearing Loss, Sensorineural; Male; No-Observed-Adverse-Effect Level; Occupational Exposure; Rats; Solvents; Spectrophotometry, Infrared; Trichloroethylene

1997
Trichloroethylene activates CD4+ T cells: potential role in an autoimmune response.
    Drug metabolism reviews, 1999, Volume: 31, Issue:4

    Topics: Animals; Antibodies, Antinuclear; Autoimmunity; Biomarkers; CD4-Positive T-Lymphocytes; Disease Models, Animal; Hyaluronan Receptors; Immunoglobulin G; Leukocyte Common Antigens; Lymphocyte Activation; Mice; Mice, Inbred MRL lpr; Solvents; Spleen; Trichloroethylene

1999
Inhibition of CYP2E1 reverses CD4+ T-cell alterations in trichloroethylene-treated MRL+/+ mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 54, Issue:2

    Topics: Allyl Compounds; Animals; Autoimmune Diseases; Autoimmunity; CD4-Positive T-Lymphocytes; Cytochrome P-450 CYP2E1 Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Female; Interleukin-4; Lymphocyte Activation; Mice; Mice, Inbred Strains; Microsomes, Liver; Solvents; Spleen; Sulfides; Trichloroethylene

2000
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020