Page last updated: 2024-11-05

trichlormethiazide and Pseudohypoaldosteronism

trichlormethiazide has been researched along with Pseudohypoaldosteronism in 2 studies

Trichlormethiazide: A thiazide diuretic with properties similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
trichlormethiazide : A benzothiadiazine, hydrogenated at positions 2, 3 and 4 and substituted with an aminosulfonyl group at C-7, a chloro substituent at C-6 and a dichloromethyl group at C-3 and with S-1 as an S,S-dioxide. A sulfonamide antibiotic, it is used as a diuretic to treat oedema (including that associated with heart failure) and hypertension.

Pseudohypoaldosteronism: A heterogeneous group of disorders characterized by renal electrolyte transport dysfunctions. Congenital forms are rare autosomal disorders characterized by neonatal hypertension, HYPERKALEMIA, increased RENIN activity and ALDOSTERONE concentration. The Type I features HYPERKALEMIA with sodium wasting; Type II, HYPERKALEMIA without sodium wasting. Pseudohypoaldosteronism can be the result of a defective renal electrolyte transport protein or acquired after KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
"Four genes responsible for pseudohypoaldosteronism type II (PHA-II) have been identified, thereby facilitating molecular diagnostic testing."1.39CUL3 gene analysis enables early intervention for pediatric pseudohypoaldosteronism type II in infancy. ( Isobe, K; Kawaguchi, H; Nonoyama, S; Ogura, Y; Osawa, M; Uchida, S, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Osawa, M1
Ogura, Y1
Isobe, K1
Uchida, S1
Nonoyama, S1
Kawaguchi, H1
Uzu, T1
Takahara, K1
Yamauchi, A1

Other Studies

2 other studies available for trichlormethiazide and Pseudohypoaldosteronism

ArticleYear
CUL3 gene analysis enables early intervention for pediatric pseudohypoaldosteronism type II in infancy.
    Pediatric nephrology (Berlin, Germany), 2013, Volume: 28, Issue:9

    Topics: Acid-Base Imbalance; Acidosis; Bicarbonates; Blood Pressure; Chlorides; Cullin Proteins; Diuretics;

2013
Change in the circadian rhythm of blood pressure in pseudo-hypoaldosteronism type 2 in response to thiazide diuretics.
    Clinical nephrology, 2004, Volume: 61, Issue:5

    Topics: Adult; Blood Pressure; Circadian Rhythm; Diuretics; Female; Humans; Pseudohypoaldosteronism; Sodium

2004