trichlormethiazide has been researched along with Hypokalemia in 7 studies
Trichlormethiazide: A thiazide diuretic with properties similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
trichlormethiazide : A benzothiadiazine, hydrogenated at positions 2, 3 and 4 and substituted with an aminosulfonyl group at C-7, a chloro substituent at C-6 and a dichloromethyl group at C-3 and with S-1 as an S,S-dioxide. A sulfonamide antibiotic, it is used as a diuretic to treat oedema (including that associated with heart failure) and hypertension.
Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trichlormethiazide, a thiazide diuretic, was introduced in 1960 and remains one of the most frequently used diuretics for treating hypertension in Japan." | 3.77 | Adverse effect profile of trichlormethiazide: a retrospective observational study. ( Asai, S; Nakayama, T; Nishida, Y; Takahashi, Y, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takahashi, Y | 1 |
| Nishida, Y | 1 |
| Nakayama, T | 1 |
| Asai, S | 1 |
| Ueda, K | 1 |
| Makita, N | 1 |
| Kawarazaki, H | 1 |
| Fujiwara, T | 1 |
| Unuma, S | 1 |
| Monkawa, T | 1 |
| Hayashi, M | 1 |
| Fujita, T | 1 |
| SAARIMAA, HA | 1 |
| Uchino, K | 1 |
| Yamamura, Y | 1 |
| Saitoh, Y | 1 |
| Isozaki, S | 1 |
| Tamura, Z | 1 |
| Nakagawa, F | 1 |
| Sekine, K | 1 |
| Kojima, I | 1 |
| Seltzer, HS | 1 |
| Allen, EW | 1 |
| Awamura, M | 1 |
| Johansson, BW | 1 |
| Sievers, J | 1 |
7 other studies available for trichlormethiazide and Hypokalemia
| Article | Year |
|---|---|
Adverse effect profile of trichlormethiazide: a retrospective observational study.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Biomarkers; Blood Urea Nitrogen; Chi-Square Distri | 2011 |
A novel compound heterozygous mutation of Gitelman's syndrome in Japan, as diagnosed by an extraordinary response of the fractional excretion rate of chloride in the trichlormethiazide loading test.
Topics: Adult; Asian People; Base Sequence; Chlorides; DNA Mutational Analysis; Female; Gitelman Syndrome; H | 2012 |
A COMBINATION OF TRIAMTERENE AND THIAZIDE IN THE TREATMENT OF CARDIAC EDEMAS.
Topics: Drug Therapy; Edema; Edema, Cardiac; Heart Failure; Hypokalemia; Toxicology; Triamterene; Trichlorme | 1965 |
[Simultaneous detection methods for abused diuretics in urine and a quantitative determination method for trichlormethiazide in urine].
Topics: Adult; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Diuretics; Female; Humans; | 1984 |
Hyperglycemia and inhibition of insulin secretion during administration of diazoxide and trichlormethiazide in man.
Topics: Blood Glucose; Diabetes Mellitus; Diazoxide; Drug Synergism; Glucose Tolerance Test; Humans; Hypergl | 1969 |
Clinical studies on the acid-base balance disturbance in congestive heart failure.
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Adult; Aldosterone; Alkalosis; Arteries; Benzothiadiaz | 1969 |
The effect on serum concentration of sodium, potassium and chloride during long term treatment with some diuretics.
Topics: Alkalosis; Blood; Chlorides; Chlorthalidone; Electrolytes; Humans; Hypokalemia; Potassium; Sodium; T | 1966 |