Page last updated: 2024-11-05

trichlormethiazide and Electrolytes

trichlormethiazide has been researched along with Electrolytes in 15 studies

Trichlormethiazide: A thiazide diuretic with properties similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
trichlormethiazide : A benzothiadiazine, hydrogenated at positions 2, 3 and 4 and substituted with an aminosulfonyl group at C-7, a chloro substituent at C-6 and a dichloromethyl group at C-3 and with S-1 as an S,S-dioxide. A sulfonamide antibiotic, it is used as a diuretic to treat oedema (including that associated with heart failure) and hypertension.

Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)

Research Excerpts

ExcerptRelevanceReference
"We performed a randomized, crossover study comparing the effects of nicardipine and trichlormethiazide on insulin sensitivity in 8 untreated essential hypertensive patients."9.07Comparison of effects of nicardipine and trichlormethiazide on insulin sensitivity in hypertensive patients. ( Fujita, T; Ishibashi, K; Isogai, Y; Kageyama, S; Mimura, A; Sakurai, T; Yamamoto, J; Yokota, K, 1994)
"We performed a randomized, crossover study comparing the effects of nicardipine and trichlormethiazide on insulin sensitivity in 8 untreated essential hypertensive patients."5.07Comparison of effects of nicardipine and trichlormethiazide on insulin sensitivity in hypertensive patients. ( Fujita, T; Ishibashi, K; Isogai, Y; Kageyama, S; Mimura, A; Sakurai, T; Yamamoto, J; Yokota, K, 1994)
"In order to evaluate both the hypotensive and uric acid-retaining effects of thiazide diuretics in an animal model with hypertension, the effects of trichlormethiazide were studied using spontaneously hypertensive rats (SHR) under dietary sodium restriction."3.67Hypotensive and uric acid-retaining effects of trichlormethiazide under dietary sodium restriction in spontaneously hypertensive rats. ( Ishii, M; Iwaki, K; Yonetani, Y, 1984)
"Trichlormethiazide was given orally to rats at 10 a."1.28Chronopharmacology of trichlormethiazide in rats: (III). Influence on serum triglyceride and glucose. ( Ebihara, A; Fujimura, A; Ohashi, K; Shiga, T, 1991)
" However, the dose-response relationships for Ca++ and Na+ excretion differed slightly among these drugs."1.28Effect of S-8666 on urinary Ca++ excretion in rats. ( Miyata, K; Nakamura, M; Shimizu, T, 1989)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's6 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vizioli, A1
Ceino, A1
Iwaki, K1
Ishii, M1
Yonetani, Y1
Yamagata, T1
Kobayashi, T1
Kusaka, H2
Karasawa, A2
Kähönen, M1
Mäkynen, H1
Arvola, P1
Wuorela, H1
Pörsti, I1
Kageyama, S1
Yamamoto, J1
Mimura, A1
Ishibashi, K1
Sakurai, T1
Yokota, K1
Isogai, Y1
Fujita, T1
Nagashima, K1
Sato, K1
Kim, S1
Hamaguchi, A1
Shinkawa, T1
Kato, Y1
Tsuchiya, N1
Miura, K1
Ohta, K1
Iwao, H1
Ueda, M2
Matsuda, S2
Tonda, K1
Matsunaga, K1
Fujimura, A1
Shiga, T1
Ohashi, K1
Ebihara, A1
Kisters, K1
Zidek, W1
Rahn, KH1
Shimizu, T1
Miyata, K1
Nakamura, M1
Urakabe, S1
Shirai, D1
Johansson, BW1
Sievers, J1
Clausen, E1
Funder, J1
Nielsen, OE1
Trap-Jensen, J1
Vejlsgård, V1
Wieth, JO1

Trials

2 trials available for trichlormethiazide and Electrolytes

ArticleYear
Comparison of effects of nicardipine and trichlormethiazide on insulin sensitivity in hypertensive patients.
    American journal of hypertension, 1994, Volume: 7, Issue:5

    Topics: Adult; Blood Pressure; Electrolytes; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hypert

1994
[Action of trichlormethiazide and amiloride on cellular Na+, K+ and Mg+ concentrations].
    Schweizerische medizinische Wochenschrift, 1989, Dec-16, Volume: 119, Issue:50

    Topics: Amiloride; Drug Combinations; Electrolytes; Erythrocytes; Humans; Magnesium; Potassium; Sodium; Spec

1989

Other Studies

13 other studies available for trichlormethiazide and Electrolytes

ArticleYear
[Clinical experience with prolonged treatment of elderly patients with an oral diuretic: trichlormethiazide. Observations on pressure behavior, electrolyte levels and blood urea, uric acid and glucide metabolism].
    Minerva medica, 1967, Feb-24, Volume: 58, Issue:16

    Topics: Aged; Blood Glucose; Blood Urea Nitrogen; Electrolytes; Female; Humans; Hypertension; Male; Trichlor

1967
Hypotensive and uric acid-retaining effects of trichlormethiazide under dietary sodium restriction in spontaneously hypertensive rats.
    Japanese journal of pharmacology, 1984, Volume: 36, Issue:3

    Topics: Animals; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Drinking; Electrolytes; Hematocrit; H

1984
Diuretic effects of KW-3902, a novel adenosine A1-receptor antagonist, in anesthetized dogs.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:12

    Topics: Anesthesia; Animals; Diuretics; Dogs; Electrolytes; Female; Furosemide; Glomerular Filtration Rate;

1994
Arterial function after trichlormethiazide therapy in spontaneously hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3

    Topics: Animals; Body Weight; Calcium; Electrolytes; Endothelium, Vascular; Feeding Behavior; Heart; Heart R

1995
Effects of KW-3902, a novel adenosine A1-receptor antagonist, on cephaloridine-induced acute renal failure in rats.
    Japanese journal of pharmacology, 1994, Volume: 64, Issue:1

    Topics: Acute Kidney Injury; Animals; Cephaloridine; Diuretics; Electrolytes; Furosemide; Male; Purinergic P

1994
Molecular effects of M17055, furosemide and thiazide on cardiac hypertrophy of spontaneously hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:2

    Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Collagen; Diuretics; Electrolytes; Furosemide; G

1996
Inhibitory effect of trichlormethiazide on development of DOC hypertension in rats.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:5

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Desoxycorticosterone; Diuretics; Elec

1977
Antihypertensive effect of trichlormethiazide in spontaneously hypertensive rats.
    Japanese journal of pharmacology, 1978, Volume: 28, Issue:4

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Catecholamines; Diuretics; Drinking; Electrolytes;

1978
Chronopharmacology of trichlormethiazide in rats: (III). Influence on serum triglyceride and glucose.
    Japanese journal of pharmacology, 1991, Volume: 57, Issue:3

    Topics: Animals; Blood Glucose; Chlorides; Circadian Rhythm; Electrolytes; Lipids; Male; Rats; Rats, Inbred

1991
Effect of S-8666 on urinary Ca++ excretion in rats.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:2

    Topics: Animals; Calcium; Diuretics; Electrolytes; Furosemide; Male; Rats; Rats, Inbred Strains; Sodium; Sul

1989
[Diabetes insipidus--antidiuretic action of diuretics].
    Nihon rinsho. Japanese journal of clinical medicine, 1970, Volume: 28, Issue:4

    Topics: Chlorothiazide; Diabetes Insipidus; Diuresis; Diuretics; Electrolytes; Humans; Hydrochlorothiazide;

1970
The effect on serum concentration of sodium, potassium and chloride during long term treatment with some diuretics.
    Angiology, 1966, Volume: 17, Issue:2

    Topics: Alkalosis; Blood; Chlorides; Chlorthalidone; Electrolytes; Humans; Hypokalemia; Potassium; Sodium; T

1966
[Effect of trichlormethiazide and triamterene on blood pressure, serum electrolytes and erythrocyte sodium].
    Nordisk medicin, 1966, Sep-08, Volume: 76, Issue:36

    Topics: Electrolytes; Erythrocytes; Female; Humans; Hypertension; Male; Potassium Chloride; Sodium; Triamter

1966