trichlormethiazide has been researched along with Cardiomegaly in 3 studies
Trichlormethiazide: A thiazide diuretic with properties similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
trichlormethiazide : A benzothiadiazine, hydrogenated at positions 2, 3 and 4 and substituted with an aminosulfonyl group at C-7, a chloro substituent at C-6 and a dichloromethyl group at C-3 and with S-1 as an S,S-dioxide. A sulfonamide antibiotic, it is used as a diuretic to treat oedema (including that associated with heart failure) and hypertension.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rosiglitazone treatment induced volume expansion and CH in wild-type and PPARĪ³ heterozygous knockout (Pparg(+/-)) mice, but not in mice defective for ligand binding (Pparg(P465L/+))." | 1.40 | Diuretics prevent thiazolidinedione-induced cardiac hypertrophy without compromising insulin-sensitizing effects in mice. ( Chang, CS; Chen, JY; Ho, LC; Maeda, N; Pandya, K; Sung, JM; Tsai, PJ; Tsai, YS, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, CS | 1 |
| Tsai, PJ | 1 |
| Sung, JM | 1 |
| Chen, JY | 1 |
| Ho, LC | 1 |
| Pandya, K | 1 |
| Maeda, N | 1 |
| Tsai, YS | 1 |
| Kim, S | 1 |
| Hamaguchi, A | 1 |
| Shinkawa, T | 1 |
| Kato, Y | 1 |
| Tsuchiya, N | 1 |
| Miura, K | 1 |
| Ohta, K | 1 |
| Iwao, H | 1 |
| Yamada, T | 1 |
| Kubota, T | 1 |
| Endo, T | 1 |
| Komatus, H | 1 |
| Oba, M | 1 |
| Nagata, H | 1 |
| Izumiyama, T | 1 |
3 other studies available for trichlormethiazide and Cardiomegaly
| Article | Year |
|---|---|
Diuretics prevent thiazolidinedione-induced cardiac hypertrophy without compromising insulin-sensitizing effects in mice.
Topics: Animals; Cardiac Volume; Cardiomegaly; Diuretics; Extracellular Signal-Regulated MAP Kinases; Furose | 2014 |
Molecular effects of M17055, furosemide and thiazide on cardiac hypertrophy of spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Collagen; Diuretics; Electrolytes; Furosemide; G | 1996 |
Effects of antihypertensive treatment on left ventricular hypertrophy in patients with essential hypertension.
Topics: Adult; Aged; Animals; Antihypertensive Agents; Cardiomegaly; Electrocardiography; Female; Heart Vent | 1979 |