Page last updated: 2024-11-05

trichlormethiazide and Blood Pressure, High

trichlormethiazide has been researched along with Blood Pressure, High in 109 studies

Trichlormethiazide: A thiazide diuretic with properties similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
trichlormethiazide : A benzothiadiazine, hydrogenated at positions 2, 3 and 4 and substituted with an aminosulfonyl group at C-7, a chloro substituent at C-6 and a dichloromethyl group at C-3 and with S-1 as an S,S-dioxide. A sulfonamide antibiotic, it is used as a diuretic to treat oedema (including that associated with heart failure) and hypertension.

Research Excerpts

ExcerptRelevanceReference
" We compared the efficacy and safety between eplerenone and trichlormethiazide in hypertensives with overweight or obesity."9.30Effects of eplerenone on blood pressure and glucose metabolism in Japanese hypertensives with overweight or obesity. ( Adachi, H; Fukumoto, Y; Kakuma, T; Kawaguchi, M; Kumagai, E, 2019)
"This study compared the efficacy and safety of azelnidipine with that of trichlormethiazide in Japanese type 2 diabetic patients with hypertension."9.20Comparison of Azelnidipine and Trichlormethiazide in Japanese Type 2 Diabetic Patients with Hypertension: The COAT Randomized Controlled Trial. ( Kawasaki, S; Kimura, M; Kondo, Y; Nakamura, A; Takihata, M; Terauchi, Y, 2015)
"We performed a randomized, crossover study comparing the effects of nicardipine and trichlormethiazide on insulin sensitivity in 8 untreated essential hypertensive patients."9.07Comparison of effects of nicardipine and trichlormethiazide on insulin sensitivity in hypertensive patients. ( Fujita, T; Ishibashi, K; Isogai, Y; Kageyama, S; Mimura, A; Sakurai, T; Yamamoto, J; Yokota, K, 1994)
"Enalapril and trichlormethiazide were compared with respect to effects on the quality of life in a crossover study of 36 patients with hypertension."9.07Crossover trial comparison of enalapril maleate and trichlormethiazide in the treatment of essential hypertension: emphasis on the quality of life. ( Hayashi, H; Ishizaka, K; Kisamori, K; Kobayashi, A; Yamazaki, N, 1992)
"Following a placebo period of 2 weeks 39 patients with essential hypertension were given during 4 weeks a combination of 2 mg trichlormethiazide and 2 mg amiloride (Esmalorid)."9.05[A trichlormethiazide-amiloride combination in essential hypertension]. ( Heintz, B; Kirch, W; Kirsten, R, 1985)
"We investigated the pathophysiological role of the cardiac adrenomedullin (AM) system, including the ligand, receptor and amidating activity in the hypertrophied heart in severe hypertension."7.72Upregulation of ligand, receptor system, and amidating activity of adrenomedullin in left ventricular hypertrophy of severely hypertensive rats: effects of angiotensin-converting enzyme inhibitors and diuretic. ( Akimoto, K; Minamino, N; Mori, Y; Nishikimi, T; Tadokoro, K; Wang, X, 2003)
"The antihypertensive effect of thiazide diuretics in angiotensin II induced hypertension has never been characterized."7.71Characterization of the antihypertensive effect of a thiazide diuretic in angiotensin II-induced hypertension. ( Ballew, JR; Fink, GD, 2001)
"Captopril is an orally active angiotensin-converting enzyme inhibitor that has been widely used in treating hypertension."7.67Cough associated with the use of captopril. ( Kaneko, Y; Sesoko, S, 1985)
"Morning hypertension has been reported to be an important risk factor for cardiovascular events, and arterial stiffness bears a relationship with cardiovascular risk."6.74Evaluation of arterial stiffness in morning hypertension under high-dose valsartan compared to valsartan plus low-dose diuretic. ( Takami, T, 2009)
"Left ventricular hypertrophy was observed in all of the patients, ie."6.69The regression of left ventricular hypertrophy by imidapril and the reduction of serum procollagen type III amino-terminal peptide in hypertensive patients. ( Arakawa, K; Koga, M; Noda, K; Notomo, J; Sasaguri, M; Tashiro, E; Tsuji, E, 2000)
"For the treatment of hypertension, the combination of an angiotensin-converting enzyme (ACE) inhibitor and a thiazide diuretic is supported by multiple lines of evidence, because these drugs have synergistic action and are expected to cancel out each other's adverse side effects."6.68Long-term evaluation of combined antihypertensive therapy with lisinopril and a thiazide diuretic in patients with essential hypertension. ( Doi, Y; Domae, A; Ebihara, A; Ishimitsu, T; Kimura, M; Murata, K; Sagara, E; Sakamaki, T; Shibata, A; Sugishita, Y; Yagi, S, 1997)
" Urinary norepinephrine excretion and oxidative stress in the brain were decreased in both IRB and IRB/TCM groups without any adverse effect on the metabolic profile."5.42Combining irbesartan and trichlormethiazide enhances blood pressure reduction via inhibition of sympathetic activity without adverse effects on metabolism in hypertensive rats with metabolic syndrome. ( Hirooka, Y; Nishihara, M; Sunagawa, K, 2015)
" We compared the efficacy and safety between eplerenone and trichlormethiazide in hypertensives with overweight or obesity."5.30Effects of eplerenone on blood pressure and glucose metabolism in Japanese hypertensives with overweight or obesity. ( Adachi, H; Fukumoto, Y; Kakuma, T; Kawaguchi, M; Kumagai, E, 2019)
"This study compared the efficacy and safety of azelnidipine with that of trichlormethiazide in Japanese type 2 diabetic patients with hypertension."5.20Comparison of Azelnidipine and Trichlormethiazide in Japanese Type 2 Diabetic Patients with Hypertension: The COAT Randomized Controlled Trial. ( Kawasaki, S; Kimura, M; Kondo, Y; Nakamura, A; Takihata, M; Terauchi, Y, 2015)
" In this study, we investigated basal EPC functions in normotensive control subjects and patients with essential hypertension and the effect of losartan on EPC function in hypertensive patients."5.19Effects of an angiotensin II receptor blocker on the impaired function of endothelial progenitor cells in patients with essential hypertension. ( Fukuda, N; Katakawa, M; Matsumoto, T; Soma, M; Suzuki, R; Tahira, Y; Tsunemi, A; Ueno, T, 2014)
"The combination of losartan and low-dose diuretics effectively treated hypertension in elderly patients while minimizing the metabolic consequences of diuretic therapy."5.09Influence of the angiotensin II receptor antagonist losartan on diuretic-induced metabolic effects in elderly hypertensive patients: comparison with a calcium channel blocker. ( Kohno, M; Masugata, H; Ohmori, K; Ohnishi, K; Takagi, Y; Wada, Y; Yukiiri, K, 2001)
"We performed a randomized, crossover study comparing the effects of nicardipine and trichlormethiazide on insulin sensitivity in 8 untreated essential hypertensive patients."5.07Comparison of effects of nicardipine and trichlormethiazide on insulin sensitivity in hypertensive patients. ( Fujita, T; Ishibashi, K; Isogai, Y; Kageyama, S; Mimura, A; Sakurai, T; Yamamoto, J; Yokota, K, 1994)
"Enalapril and trichlormethiazide were compared with respect to effects on the quality of life in a crossover study of 36 patients with hypertension."5.07Crossover trial comparison of enalapril maleate and trichlormethiazide in the treatment of essential hypertension: emphasis on the quality of life. ( Hayashi, H; Ishizaka, K; Kisamori, K; Kobayashi, A; Yamazaki, N, 1992)
"Following a placebo period of 2 weeks 39 patients with essential hypertension were given during 4 weeks a combination of 2 mg trichlormethiazide and 2 mg amiloride (Esmalorid)."5.05[A trichlormethiazide-amiloride combination in essential hypertension]. ( Heintz, B; Kirch, W; Kirsten, R, 1985)
"Trichlormethiazide, a thiazide diuretic, was introduced in 1960 and remains one of the most frequently used diuretics for treating hypertension in Japan."3.77Adverse effect profile of trichlormethiazide: a retrospective observational study. ( Asai, S; Nakayama, T; Nishida, Y; Takahashi, Y, 2011)
"Candesartan, an ARB, improves EPC dysfunction and increases cardiac c-kit expression through the anti-oxidative mechanism in hypertension."3.74Effects of an ARB on endothelial progenitor cell function and cardiovascular oxidation in hypertension. ( Fukuda, N; Kobayashi, N; Matsumoto, K; Matsumoto, T; Suzuki, R; Tahira, Y; Ueno, T; Yao, EH; Yu, Y, 2008)
"We investigated the pathophysiological role of the cardiac adrenomedullin (AM) system, including the ligand, receptor and amidating activity in the hypertrophied heart in severe hypertension."3.72Upregulation of ligand, receptor system, and amidating activity of adrenomedullin in left ventricular hypertrophy of severely hypertensive rats: effects of angiotensin-converting enzyme inhibitors and diuretic. ( Akimoto, K; Minamino, N; Mori, Y; Nishikimi, T; Tadokoro, K; Wang, X, 2003)
"The antihypertensive effect of thiazide diuretics in angiotensin II induced hypertension has never been characterized."3.71Characterization of the antihypertensive effect of a thiazide diuretic in angiotensin II-induced hypertension. ( Ballew, JR; Fink, GD, 2001)
"In order to evaluate both the hypotensive and uric acid-retaining effects of thiazide diuretics in an animal model with hypertension, the effects of trichlormethiazide were studied using spontaneously hypertensive rats (SHR) under dietary sodium restriction."3.67Hypotensive and uric acid-retaining effects of trichlormethiazide under dietary sodium restriction in spontaneously hypertensive rats. ( Ishii, M; Iwaki, K; Yonetani, Y, 1984)
"Captopril is an orally active angiotensin-converting enzyme inhibitor that has been widely used in treating hypertension."3.67Cough associated with the use of captopril. ( Kaneko, Y; Sesoko, S, 1985)
"A 65-year-old female patient suffering from hypertension and myxedema due to chronic thyroiditis developed anginal attacks under trichlormethiazide therapy."3.65Sinus arrest following diuretic therapy in a patient with myxedema and hypertension. ( Kawasaki, S; Masuya, H; Takeda, R; Tsutchiya, M; Ueno, T, 1975)
"The optimal combination treatment for hypertension has not been established."2.75Combination therapy of calcium channel blocker and angiotensin II receptor blocker reduces augmentation index in hypertensive patients. ( Doi, M; Hirohata, S; Kaji, Y; Kamikawa, S; Kusachi, S; Miyoshi, T; Ninomiya, Y; Ogawa, H; Sakane, K; Usui, S, 2010)
" In this study, the efficacy of treatment using an angiotensin II receptor antagonist (ARB) combined with a calcium channel blocker (CCB) or a diuretic was compared from multiple perspectives in patients with hypertension."2.74Angiotensin-II receptor antagonist combined with calcium channel blocker or diuretic for essential hypertension. ( Akabane, T; Ishimitsu, T; Masuda, T; Matsuoka, H; Minami, J; Numabe, A; Okamura, A, 2009)
"Morning hypertension has been reported to be an important risk factor for cardiovascular events, and arterial stiffness bears a relationship with cardiovascular risk."2.74Evaluation of arterial stiffness in morning hypertension under high-dose valsartan compared to valsartan plus low-dose diuretic. ( Takami, T, 2009)
" However, the total incidence of adverse reactions, including non-CV events and unfavorable BP changes, was 31 cases (15."2.70Tolerability and safety of a calcium channel blocker in comparison with a diuretic in the treatment of elderly patients with hypertension: secondary analysis of the NICS-EH. ( Abe, K; Fujishima, M; Fukiyama, K; Hiwada, K; Iimura, O; Ishii, M; Kuramoto, K; Kuwajima, I; Ogihara, T; Saruta, T, 2001)
"Left ventricular hypertrophy was observed in all of the patients, ie."2.69The regression of left ventricular hypertrophy by imidapril and the reduction of serum procollagen type III amino-terminal peptide in hypertensive patients. ( Arakawa, K; Koga, M; Noda, K; Notomo, J; Sasaguri, M; Tashiro, E; Tsuji, E, 2000)
"For the treatment of hypertension, the combination of an angiotensin-converting enzyme (ACE) inhibitor and a thiazide diuretic is supported by multiple lines of evidence, because these drugs have synergistic action and are expected to cancel out each other's adverse side effects."2.68Long-term evaluation of combined antihypertensive therapy with lisinopril and a thiazide diuretic in patients with essential hypertension. ( Doi, Y; Domae, A; Ebihara, A; Ishimitsu, T; Kimura, M; Murata, K; Sagara, E; Sakamaki, T; Shibata, A; Sugishita, Y; Yagi, S, 1997)
" Urinary norepinephrine excretion and oxidative stress in the brain were decreased in both IRB and IRB/TCM groups without any adverse effect on the metabolic profile."1.42Combining irbesartan and trichlormethiazide enhances blood pressure reduction via inhibition of sympathetic activity without adverse effects on metabolism in hypertensive rats with metabolic syndrome. ( Hirooka, Y; Nishihara, M; Sunagawa, K, 2015)
"Exercise-induced acute renal failure (ARF) developed in a 45-year-old man during antihypertensive therapy with losartan and trichlormethiazide."1.32A case of exercise-induced acute renal failure in a patient with idiopathic renal hypouricemia developed during antihypertensive therapy with losartan and trichlormethiazide. ( Hasegawa, Y; Ito, O; Ito, S; Kudo, K; Mitsui, H; Sato, H; Sato, K; Yuda, F, 2003)
"Semotiadil fumarate, a novel benzothiazine calcium antagonist, was given alone or in combination with either enalapril or trichlormethiazide to conscious, spontaneously hypertensive, rats daily for 2 weeks."1.29Antihypertensive effects of a novel calcium antagonist, semotiadil fumarate (SD-3211), alone and in combination with enalapril or trichlormethiazide in spontaneously hypertensive rats. ( Akashi, S; Ichikawa, M; Koida, M; Machidera, Y; Manno, K; Nakamuta, H; Ohtsuji, T; Wanaka, M, 1994)
"Diltiazem HCl was administered p."1.26Clinical study on the hypotensive effect of diltiazem hydrochloride. ( Maeda, K; Shiota, K; Takasugi, T; Tanaka, Y; Tsukano, Y, 1981)

Research

Studies (109)

TimeframeStudies, this research(%)All Research%
pre-199066 (60.55)18.7374
1990's19 (17.43)18.2507
2000's14 (12.84)29.6817
2010's9 (8.26)24.3611
2020's1 (0.92)2.80

Authors

AuthorsStudies
Kario, K2
Ohishi, M1
Katsuya, T2
Taguchi, T1
Tanabe, A1
Sugimoto, K1
Shimosawa, T1
Tomitani, N1
Kanegae, H1
Ishii, H1
Uchiyama, K1
Yamagiwa, K1
Shiraiwa, T1
Yoshida, T1
Kanda, K1
Hasegawa, S1
Hoshide, S1
Adachi, H1
Kakuma, T1
Kawaguchi, M1
Kumagai, E1
Fukumoto, Y1
Suzuki, R2
Fukuda, N2
Katakawa, M1
Tsunemi, A1
Tahira, Y2
Matsumoto, T2
Ueno, T3
Soma, M1
Nishihara, M1
Hirooka, Y1
Sunagawa, K1
Takihata, M1
Nakamura, A1
Kondo, Y1
Kawasaki, S2
Kimura, M2
Terauchi, Y1
Ushigome, E1
Matsumoto, S1
Oyabu, C1
Ushigome, H1
Yokota, I1
Hasegawa, G1
Nakamura, N1
Tanaka, M1
Yamazaki, M1
Fukui, M1
Ishimitsu, T2
Numabe, A2
Masuda, T1
Akabane, T1
Okamura, A1
Minami, J1
Matsuoka, H4
Takami, T1
Yutaka, M1
Mifune, M1
Kubota, E1
Itoh, H1
Saito, I1
Doi, M1
Miyoshi, T1
Hirohata, S1
Kamikawa, S1
Usui, S1
Kaji, Y1
Sakane, K1
Ogawa, H1
Ninomiya, Y1
Kusachi, S1
Sato, K2
Dohi, Y1
Kojima, M1
Takase, H1
Suzuki, S1
Ito, S3
Takahashi, Y1
Nishida, Y1
Nakayama, T1
Asai, S1
Wang, X1
Nishikimi, T1
Akimoto, K1
Tadokoro, K1
Mori, Y1
Minamino, N1
Ito, O1
Hasegawa, Y1
Mitsui, H1
Yuda, F1
Sato, H1
Kudo, K1
ERNST, EM2
TETSUKA, U1
OGURO, Y1
MOTOKI, Y1
GELLMAN, DD1
BARENBERG, RL1
GIFFORD, RW1
BAUGH, JE1
WEST, RO1
OKUN, R2
RUSSELL, RP2
WILSON, WR1
WOELFER, HJ1
SCHNEIDER, KW1
HOCHREIN, H1
WILLUMSEN, J2
CLAUSEN, E2
GALSKOV, A1
WOLFF, FW1
LANGDON, RG1
LYON, AF1
DEGRAFF, AC1
KOBAYASHI, K1
SHIBATA, M1
FUJII, R1
KATO, K1
IWAZU, A1
CARLINER, NH1
SCHELLING, JL1
DAVIS, M1
TALSO, PJ1
REMENCHIK, AP1
BARNETT, RJ1
SERIU, Y1
MATTEY, WE1
Ogawa, S1
Mori, T1
Nako, K1
Kato, T1
Takeuchi, K1
Yu, Y1
Yao, EH1
Kobayashi, N2
Matsumoto, K1
Kadota, I1
Nishimura, Y1
Ishigami, R1
Yoshida, A1
Ido, N2
Fujita, H2
Vizioli, A1
Ceino, A1
Nakada, I1
Sekimoto, H1
Nakano, T1
Shimada, O1
Horibe, N1
Fuse, N1
Izumi, Y1
Honda, M1
Hatano, M1
Kawahara, Y1
Iwaki, K1
Ishii, M2
Yonetani, Y1
Hiramatsu, K1
Yamada, T3
Ichikawa, K1
Izumiyama, T3
Nagata, H3
Nomura, G1
Arai, S1
Maekawa, M1
Ohta, H1
Takabatake, T1
Morishita, S1
Nishimura, K1
Kato, E1
Shirahase, H1
Osumi, S1
Kitao, K1
Seki, T1
Ikuta, J1
Yamauchi, Y1
Shimizu, S1
Matsuda, S2
Matsunaga, K1
Ueda, M2
Maeda, K1
Takasugi, T1
Tsukano, Y1
Tanaka, Y1
Shiota, K1
Sketris, IS1
Skoutakis, VA1
Acchiardo, SR1
Meyer, MC1
Ichikawa, M2
Wanaka, M1
Ohtsuji, T1
Akashi, S1
Machidera, Y1
Manno, K1
Nakamuta, H1
Koida, M1
Kuramoto, K5
Kageyama, S1
Yamamoto, J1
Mimura, A1
Ishibashi, K1
Sakurai, T1
Yokota, K1
Isogai, Y1
Fujita, T1
Ogura, T1
Nishida, N1
Watanabe, H1
Omiya, T1
Yamauchi, T1
Hosoya, M1
Hirata, H1
Kashihara, N1
Ota, Z1
Nomura, H1
Nagashima, K1
Kusaka, H1
Karasawa, A1
Kumagai, K1
Suzuki, H2
Jimbo, M1
Nishizawa, M1
Ryuzaki, M1
Saruta, T3
Takanohashi, A1
Tojo, A2
Yagi, S3
Ishii, R2
Tagawa, T2
Ishida, T2
Naruse, T2
Kim, S1
Hamaguchi, A1
Shinkawa, T1
Kato, Y2
Tsuchiya, N1
Miura, K1
Ohta, K1
Iwao, H1
Namba, K1
Ichihara, K1
Okumura, K1
Kamei, H1
Nagasaka, M1
Kanda, A1
Kanno, T1
Miyoshi, K1
Miyake, H1
Ebihara, A2
Doi, Y2
Domae, A1
Shibata, A1
Sugishita, Y1
Sagara, E1
Sakamaki, T1
Murata, K1
Honda, T1
Hamada, M1
Shigematsu, Y1
Matsumoto, Y1
Hiwada, K2
Ogihara, T2
Sasaguri, M1
Noda, K1
Tashiro, E1
Notomo, J1
Tsuji, E1
Koga, M1
Arakawa, K1
Gomi, T1
Ikeda, T1
Shibuya, Y1
Nagao, R1
Shionoiri, H1
Kosaka, T1
Kita, E1
Takizawa, T1
Takasaki, I1
Ballew, JR1
Fink, GD1
Kuwajima, I2
Iimura, O1
Abe, K1
Fujishima, M1
Fukiyama, K1
Ohnishi, K1
Kohno, M1
Yukiiri, K1
Masugata, H1
Wada, Y1
Takagi, Y1
Ohmori, K1
Stokkeland, OM1
Sangvik, K1
Ditlefsen, EM1
Linée, P1
Le Pollès, JB1
Lacroix, P1
Pape, D1
Quiniou, P1
Van den Driessche, J1
Kubota, T1
Endo, T2
Komatus, H1
Oba, M1
Shimizu, N2
Miyashita, H2
Koide, K1
Inoue, N1
Ogasawara, M1
Zdichynec, B1
Yamaguchi, I1
Ikezawa, K1
Murata, S1
Narita, H1
Ikeo, T1
Sato, M1
Ito, K1
Matsushita, S1
Mifune, J1
Sakai, M1
Iwasaki, T1
Murakami, M1
Jinnouchi, T1
Mimura, G1
Sadanaga, T1
Ono, K1
Sakamoto, Y1
Masso, M1
Gimeno Martínez, J1
Honorato, J1
Terasawa, F1
Takeda, R1
Tsutchiya, M1
Masuya, H1
Sasaki, J1
Tominaga, K1
Saeki, Y1
Kawasaki, K1
Sumida, I1
Ikeda, K1
Gondo, K1
Saku, K1
Kobayashi, A1
Hayashi, H1
Kisamori, K1
Ishizaka, K1
Yamazaki, N1
Kimura, K1
Sugimoto, T1
Itami, N1
Yamamoto, K1
Andoh, T1
Akutsu, Y1
Fujimura, A1
Ohashi, K1
Watari, H1
Uehara, Y1
Hirawa, N1
Takada, S1
Tominaga, T1
Kumagai, H1
Minami, M2
Hamaue, N2
Togashi, H2
Matsumoto, M2
Yoshioka, M2
Saito, H2
Amemiya, N1
Yamada, K1
Kirsten, R1
Kirch, W1
Heintz, B1
Sesoko, S1
Kaneko, Y1
Pabst, J1
Leopold, G1
Ungethüm, W1
Simane, Z1
Bühring, KU1
Okada, F1
Nakamura, H1
Bergbauer, M1
Mata, O1
Kjaerulff, J1
Lyngsoe, J1
Lindheimer, MD1
Roux, J1
Yasui, H1
Gjonnaess, H1
Momose, M1
Takasawa, A1
Imamura, B1
Hasegawa, M1
Asano, T1
Namba, H1
Takayama, J1
Miyazaki, H1
Tsuboniwa, M1
Funder, J1
Nielsen, OE1
Trap-Jensen, J1
Vejlsgård, V1
Wieth, JO1

Reviews

1 review available for trichlormethiazide and Blood Pressure, High

ArticleYear
[Low renin essential hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1973, Volume: 31, Issue:11

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium; Renin; Spironolactone; Trichlormet

1973

Trials

30 trials available for trichlormethiazide and Blood Pressure, High

ArticleYear
Rationale and design of a multicenter randomized study comparing the efficacy and safety of esaxerenone versus trichlormethiazide in patients with uncontrolled essential hypertension: EXCITE-HT study.
    Journal of clinical hypertension (Greenwich, Conn.), 2023, Volume: 25, Issue:9

    Topics: Antihypertensive Agents; Blood Pressure; Essential Hypertension; Humans; Hypertension; Trichlormethi

2023
Comparative Effects of an Angiotensin II Receptor Blocker (ARB)/Diuretic vs. ARB/Calcium-Channel Blocker Combination on Uncontrolled Nocturnal Hypertension Evaluated by Information and Communication Technology-Based Nocturnal Home Blood Pressure Monitorin
    Circulation journal : official journal of the Japanese Circulation Society, 2017, Jun-23, Volume: 81, Issue:7

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure Monitoring, A

2017
Effects of eplerenone on blood pressure and glucose metabolism in Japanese hypertensives with overweight or obesity.
    Medicine, 2019, Volume: 98, Issue:15

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Eplerenone; Female; Glucose; Humans; Hypertension; Hy

2019
Effects of an angiotensin II receptor blocker on the impaired function of endothelial progenitor cells in patients with essential hypertension.
    American journal of hypertension, 2014, Volume: 27, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cell Proliferation

2014
Comparison of Azelnidipine and Trichlormethiazide in Japanese Type 2 Diabetic Patients with Hypertension: The COAT Randomized Controlled Trial.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Aged; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2;

2015
Angiotensin-II receptor antagonist combined with calcium channel blocker or diuretic for essential hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:11

    Topics: Adult; Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Ankle Brachial Index; Azetidineca

2009
Evaluation of arterial stiffness in morning hypertension under high-dose valsartan compared to valsartan plus low-dose diuretic.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:12

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Ankle Brachial Index; Blood Flow Velocity; Blood Pres

2009
Comparison of effects of low dose of spironolactone and a thiazide diuretic in patients with hypertension treated with an angiotensin-converting enzyme inhibitor or an angiotensin type 1 receptor blocker.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2009, Volume: 31, Issue:8

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Blood Press

2009
Combination therapy of calcium channel blocker and angiotensin II receptor blocker reduces augmentation index in hypertensive patients.
    The American journal of the medical sciences, 2010, Volume: 339, Issue:5

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Blood Pressure; Calcium Cha

2010
Antioxidative effects of thiazide diuretics in refractory hypertensive patients. A randomized crossover trial of chlortalidone and trichlormethiazide.
    Arzneimittel-Forschung, 2010, Volume: 60, Issue:10

    Topics: Aged; Antioxidants; Blood Chemical Analysis; Blood Pressure; C-Reactive Protein; Calcium Channel Blo

2010
Angiotensin II type 1 receptor blockers reduce urinary oxidative stress markers in hypertensive diabetic nephropathy.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 47, Issue:4

    Topics: Adult; Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimid

2006
Treatment of elderly hypertensives in Japan: National Intervention Cooperative Study in Elderly Hypertensives. The National Intervention Cooperative Study Group.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1994, Volume: 12, Issue:6

    Topics: Aged; Cardiovascular Diseases; Cerebrovascular Disorders; Double-Blind Method; Female; Humans; Hyper

1994
Comparison of effects of nicardipine and trichlormethiazide on insulin sensitivity in hypertensive patients.
    American journal of hypertension, 1994, Volume: 7, Issue:5

    Topics: Adult; Blood Pressure; Electrolytes; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hypert

1994
Long-term evaluation of combined antihypertensive therapy with lisinopril and a thiazide diuretic in patients with essential hypertension.
    Japanese heart journal, 1997, Volume: 38, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; B

1997
Effect of antihypertensive therapy on aortic distensibility in patients with essential hypertension: comparison with trichlormethiazide, nicardipine and alacepril.
    Cardiovascular drugs and therapy, 1999, Volume: 13, Issue:4

    Topics: Age Factors; Antihypertensive Agents; Aorta; Blood Pressure; Captopril; Echocardiography; Elasticity

1999
Randomized double-blind comparison of a calcium antagonist and a diuretic in elderly hypertensives. National Intervention Cooperative Study in Elderly Hypertensives Study Group.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:5

    Topics: Aged; Blood Pressure; Calcium Channel Blockers; Diuretics; Double-Blind Method; Female; Humans; Hype

1999
Effect of long-term treatment with antihypertensive drugs on quality of life of elderly patients with hypertension: a double-blind comparative study between a calcium antagonist and a diuretic. NICS-EH Study Group. National Intervention Cooperative Study
    Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23, Issue:1

    Topics: Aged; Blood Pressure; Calcium Channel Blockers; Diuretics; Double-Blind Method; Female; Follow-Up St

2000
The regression of left ventricular hypertrophy by imidapril and the reduction of serum procollagen type III amino-terminal peptide in hypertensive patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23, Issue:4

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug

2000
Comparison of long-term therapeutic effect of an ACE inhibitor, temocapril, with that of a diuretic on microalbuminuria in non-diabetic essential hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23, Issue:6

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Creatinine; Diuretics; Humans; Hypertension;

2000
Tolerability and safety of a calcium channel blocker in comparison with a diuretic in the treatment of elderly patients with hypertension: secondary analysis of the NICS-EH.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2001, Volume: 24, Issue:5

    Topics: Aged; Calcium Channel Blockers; Disease-Free Survival; Diuretics; Follow-Up Studies; Humans; Hyperte

2001
Influence of the angiotensin II receptor antagonist losartan on diuretic-induced metabolic effects in elderly hypertensive patients: comparison with a calcium channel blocker.
    International journal of clinical pharmacology and therapeutics, 2001, Volume: 39, Issue:10

    Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo

2001
A comparative study of metoprolol and trichlormethiazide in hypertension.
    Current therapeutic research, clinical and experimental, 1975, Volume: 18, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials a

1975
[Comparative study of anti-aldosterone agents and hypotensive diuretics in essential hypertension by a double blind test].
    Horumon to rinsho. Clinical endocrinology, 1977, Volume: 25, Issue:2

    Topics: Clinical Trials as Topic; Drug Evaluation; Humans; Hypertension; Middle Aged; Renin; Spironolactone;

1977
[Combined treatment with beta-receptor blocker pindolol and diureticum trichlormethiazidum in patients with essential hypertony in stadium II WHO (author's transl))].
    Zeitschrift fur Kardiologie, 1977, Volume: 66, Issue:9

    Topics: Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Hu

1977
Effects of lisinopril and low-dose trichlormethiazide on lipoprotein metabolism in patients with mild to moderate hypertension.
    Journal of human hypertension, 1992, Volume: 6, Issue:3

    Topics: Adult; Aged; Antihypertensive Agents; Apolipoproteins; Blood Pressure; Cholesterol; Dipeptides; Dose

1992
Crossover trial comparison of enalapril maleate and trichlormethiazide in the treatment of essential hypertension: emphasis on the quality of life.
    Internal medicine (Tokyo, Japan), 1992, Volume: 31, Issue:2

    Topics: Aged; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Quality of Life; Surveys and Quest

1992
Effects of first-line antihypertensive agents on sexual function and sex hormones.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:4

    Topics: Adult; Antihypertensive Agents; Atenolol; Captopril; Estradiol; Follicle Stimulating Hormone; Humans

1988
[Age and efficacy of calcium entry blocker in essential hypertension--double blind trial using nicardipine].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1986, Volume: 23, Issue:2

    Topics: Adult; Age Factors; Aged; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; F

1986
[A trichlormethiazide-amiloride combination in essential hypertension].
    Deutsche medizinische Wochenschrift (1946), 1985, Mar-08, Volume: 110, Issue:10

    Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Drug Tolerance; Female; Humans;

1985
[Esmaloride--a new potassium neutral diuretic combination. Clinical pharmacologic properties].
    Fortschritte der Medizin, 1985, Feb-14, Volume: 103, Issue:6

    Topics: Aldosterone; Amiloride; Blood Glucose; Blood Pressure; Body Weight; Creatinine; Drug Combinations; F

1985

Other Studies

78 other studies available for trichlormethiazide and Blood Pressure, High

ArticleYear
Combining irbesartan and trichlormethiazide enhances blood pressure reduction via inhibition of sympathetic activity without adverse effects on metabolism in hypertensive rats with metabolic syndrome.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:1

    Topics: Animals; Antihypertensive Agents; Antioxidants; Biphenyl Compounds; Blood Pressure; Heart Rate; Hype

2015
Olmesartan with azelnidipine versus with trichlormethiazide on home blood pressure variability in patients with type II diabetes mellitus.
    Journal of the American Society of Hypertension : JASH, 2017, Volume: 11, Issue:3

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Bl

2017
Adverse effect profile of trichlormethiazide: a retrospective observational study.
    Cardiovascular diabetology, 2011, May-23, Volume: 10

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Biomarkers; Blood Urea Nitrogen; Chi-Square Distri

2011
Upregulation of ligand, receptor system, and amidating activity of adrenomedullin in left ventricular hypertrophy of severely hypertensive rats: effects of angiotensin-converting enzyme inhibitors and diuretic.
    Journal of hypertension, 2003, Volume: 21, Issue:6

    Topics: Adrenomedullin; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic F

2003
A case of exercise-induced acute renal failure in a patient with idiopathic renal hypouricemia developed during antihypertensive therapy with losartan and trichlormethiazide.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2003, Volume: 26, Issue:6

    Topics: Acute Kidney Injury; Antihypertensive Agents; Benzbromarone; Blood Cell Count; Creatinine; Diuretics

2003
Treat edema, hypertension with trichlormethiazide. Preliminary report on 67 patients.
    Pennsylvania medical journal (1928), 1960, Volume: 63

    Topics: Chlorothiazide; Edema; Hypertension; Trichlormethiazide

1960
Trichlormethiazide-reserpine combination in hypertension.
    Current therapeutic research, clinical and experimental, 1961, Volume: 3

    Topics: Chlorothiazide; Hypertension; Reserpine; Trichlormethiazide

1961
[Clinical experiences with trichlormethiazide in essential hypertension].
    Naika hokan. Japanese archives of internal medicine, 1962, Volume: 9

    Topics: Chlorothiazide; Essential Hypertension; Hypertension; Trichlormethiazide

1962
Clinical experience with an oral diuretic, trichlormethiazide.
    Canadian Medical Association journal, 1963, Jul-13, Volume: 89

    Topics: Aged; Blood Pressure; Blood Urea Nitrogen; Diuretics; Edema; Essential Hypertension; Humans; Hyperte

1963
Treatment of hypertension with trichlormethiazide. Evaluation of this drug as sole therapeutic agent.
    The Ohio State medical journal, 1963, Volume: 59

    Topics: Humans; Hypertension; Trichlormethiazide

1963
Clinical and laboratory study of trichlormethiazide and reserpine in 52 patients with hypertension.
    Angiology, 1963, Volume: 14

    Topics: Humans; Hypertension; Reserpine; Trichlormethiazide

1963
A clinical and statistical study of the effect of trichlormethiazide on blood pressure.
    The Medical annals of the District of Columbia, 1962, Volume: 31

    Topics: Blood Pressure; Blood Pressure Determination; Chlorothiazide; Hypertension; Trichlormethiazide

1962
USE OF DIAZOXIDE WITH TRICHLORMETHIAZIDE FOR HYPERTENSION.
    Archives of internal medicine, 1963, Volume: 112

    Topics: Acidosis; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Body Weight; Diazoxide; Hyperg

1963
[CLINICAL AND HEMODYNAMIC STUDIES ON A NEW ANTIHYPERTENSIVE SUBSTANCE FROM THE THIAZIDE GROUP WITHOUT DIURETIC EFFECT].
    Arzneimittel-Forschung, 1963, Volume: 13

    Topics: Antihypertensive Agents; Benzothiadiazines; Biomedical Research; Blood Circulation; Blood Pressure;

1963
[TRICHLORMETHIAZIDE (FLUITRAN) AS A DIURETIC].
    Ugeskrift for laeger, 1964, Mar-05, Volume: 126

    Topics: Bicarbonates; Blood Chemical Analysis; Chlorides; Chlorothiazide; Creatine; Creatinine; Diuretics; E

1964
[TRICHLORMETHIAZIDE (FLUITRAN) AS A HYPOTENSIVE AGENT].
    Ugeskrift for laeger, 1964, Mar-05, Volume: 126

    Topics: Antihypertensive Agents; Bicarbonates; Blood Chemical Analysis; Blood Pressure Determination; Chlori

1964
CONJOINT CLINIC ON DRUGS AND DIABETES.
    Journal of chronic diseases, 1964, Volume: 17

    Topics: Adrenalectomy; Antihypertensive Agents; Benzothiadiazines; Biomedical Research; Blood; Blood Glucose

1964
DIURETIC THERAPY. V. CLINICAL USE OF THIAZIDE DIURETICS.
    American heart journal, 1964, Volume: 68

    Topics: Chlorothiazide; Chlorthalidone; Diuretics; Drug Therapy; Humans; Hypertension; Polythiazide; Quinazo

1964
[CLINICAL EXPERIENCE OF 2,4,7-TRIAMINO-6-PHENYLPTERIDINE THERAPY UPON LONG TERM AND COMPOUND ADMINISTRATION WITH OTHER AGENTS].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1964, Jul-10, Volume: 53

    Topics: Adolescent; Biomedical Research; Chlorthalidone; Diuretics; Drug Therapy; Edema; Geriatrics; Hydroch

1964
THIAZIDE- AND PHTHALIMIDINE-INDUCED HYPERGLYCEMIA IN HYPERTENSIVE PATIENTS.
    JAMA, 1965, Feb-15, Volume: 191

    Topics: Amylases; Blood Chemical Analysis; Chlorthalidone; Creatine; Creatinine; Diabetes Mellitus; Drug The

1965
COMBINED THERAPY OF HYPERTENSIVE DISEASE: AN EVALUATION OF THE VALUE OF A PHENOTHIAZINE DERIVATIVE.
    Applied therapeutics, 1965, Volume: 7

    Topics: Biomedical Research; Blood Pressure; Blood Pressure Determination; Drug Therapy; Fluphenazine; Hyper

1965
A CLINICAL STUDY OF THE ROLE OF CATECHOLAMINE IN BLOOD PRESSURE REGULATION. URINARY EXCRETION OF CATECHOLAMINES DURING SALT RESTRICTION AND THIAZIDE MEDICATION IN HYPERTENSIVE SUBJECTS.
    Japanese circulation journal, 1965, Volume: 29

    Topics: Adolescent; Benzothiadiazines; Biomedical Research; Blood Pressure; Body Fluids; Catecholamines; Dex

1965
Product research and development: treatment of hypertension with trichlormethiazide and reserpine.
    Industrial medicine & surgery, 1962, Volume: 31

    Topics: Chlorothiazide; Hypertension; Research; Reserpine; Trichlormethiazide

1962
Effects of an ARB on endothelial progenitor cell function and cardiovascular oxidation in hypertension.
    American journal of hypertension, 2008, Volume: 21, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antioxidants; Aorta; Benz

2008
[Effect of a new diuretic agent, Furosemide, on the carbohydrate metabolism].
    Nihon Naibunpi Gakkai zasshi, 1966, Mar-20, Volume: 41, Issue:12

    Topics: Blood Glucose; Blood Urea Nitrogen; Carbohydrate Metabolism; Diabetes Mellitus; Furosemide; Glucose

1966
[Clinical studies on trichlormethiazide to hypertension, renal disorders and cerebrovascular diseases. I. About the effects as a function of time].
    Naika hokan. Japanese archives of internal medicine, 1966, Volume: 13, Issue:11

    Topics: Adolescent; Adult; Aged; Cerebrovascular Disorders; Female; Humans; Hypertension; Male; Middle Aged;

1966
[Clinical studies on trichlormethiazide to hypertension, renal disorders and cerebrovascular diseases. II. About the effects by a prolonged oral administration].
    Naika hokan. Japanese archives of internal medicine, 1966, Volume: 13, Issue:11

    Topics: Adolescent; Adult; Female; Humans; Hypertension; Male; Middle Aged; Nephritis; Trichlormethiazide

1966
[Clinical experience with prolonged treatment of elderly patients with an oral diuretic: trichlormethiazide. Observations on pressure behavior, electrolyte levels and blood urea, uric acid and glucide metabolism].
    Minerva medica, 1967, Feb-24, Volume: 58, Issue:16

    Topics: Aged; Blood Glucose; Blood Urea Nitrogen; Electrolytes; Female; Humans; Hypertension; Male; Trichlor

1967
[The effect of spironolactone and trichlormethiazide on blood pressure, plasma dry weight and plasma potassium in the elderly hypertension].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1983, Volume: 20, Issue:6

    Topics: Aged; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Plasma Volume; Potassium; Ren

1983
Combined effects of captopril and the diuretic trichloromethiazide on blood pressure in patients with essential hypertension.
    Nihon Jinzo Gakkai shi, 1984, Volume: 26, Issue:9

    Topics: Adult; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Drug Interactions; Female; Human

1984
Hypotensive and uric acid-retaining effects of trichlormethiazide under dietary sodium restriction in spontaneously hypertensive rats.
    Japanese journal of pharmacology, 1984, Volume: 36, Issue:3

    Topics: Animals; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Drinking; Electrolytes; Hematocrit; H

1984
Changes in endocrine activities relative to obesity in patients with essential hypertension.
    Journal of the American Geriatrics Society, 1981, Volume: 29, Issue:1

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Energy Intake; Female; Humans; Hy

1981
Treatment of mild to moderate hypertension: diuretic or beta-blockers?
    Japanese circulation journal, 1981, Volume: 45, Issue:7

    Topics: Adult; Age Factors; Blood Pressure; Humans; Hypertension; Middle Aged; Oxprenolol; Pindolol; Plasma

1981
[Antihypertensive and diuretic effects of indapamide in normotensive and hypertensive rats (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 79, Issue:3

    Topics: Animals; Carbonic Anhydrase Inhibitors; Desoxycorticosterone; Diuretics; Hypertension; In Vitro Tech

1982
[Effect of prazepam on experimental hypertensive models].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 79, Issue:6

    Topics: Animals; Blood Pressure; Disease Models, Animal; Drug Synergism; Female; Heart Rate; Hypertension; M

1982
[Antihypertensive and related hemodynamic effects of a thiazide in desoxycorticosterone (DOC)/saline hypertensive rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 79, Issue:5

    Topics: Animals; Desoxycorticosterone; Diuretics; Fundus Oculi; Hemodynamics; Hypertension; Kidney; Male; Or

1982
Clinical study on the hypotensive effect of diltiazem hydrochloride.
    International journal of clinical pharmacology, therapy, and toxicology, 1981, Volume: 19, Issue:2

    Topics: Adult; Aged; Benzazepines; Blood Pressure; Diltiazem; Female; Humans; Hypertension; Male; Middle Age

1981
The pharmacokinetics of trichlormethiazide in hypertensive patients with normal and compromised renal function.
    European journal of clinical pharmacology, 1981, Volume: 20, Issue:6

    Topics: Female; Humans; Hypertension; Hypertension, Renal; Kidney; Kinetics; Male; Middle Aged; Trichlormeth

1981
Antihypertensive effects of a novel calcium antagonist, semotiadil fumarate (SD-3211), alone and in combination with enalapril or trichlormethiazide in spontaneously hypertensive rats.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:11

    Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Di

1994
Alteration of renal receptors for atrial natriuretic peptide and vasopressin in spontaneously hypertensive rats treated with antihypertensive diuretics.
    Research communications in chemical pathology and pharmacology, 1994, Volume: 83, Issue:2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Furosemide; Hypertension; Indapamide; Kidney; Male

1994
Antihypertensive effects of KW-3902, an adenosine A1-receptor antagonist, in Dahl salt-sensitive rats.
    Japanese journal of pharmacology, 1995, Volume: 68, Issue:4

    Topics: Animals; Diet; Diuretics; Dose-Response Relationship, Drug; Furosemide; Hypertension; Male; Purinerg

1995
Comparison of early and late start of antihypertensive agents and baroreceptor reflexes.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:2

    Topics: Aging; Animals; Antihypertensive Agents; Atenolol; Baroreflex; Blood Pressure; Enalapril; Heart Rate

1996
Effect of trichlormethiazide and captopril on nitric oxide synthase activity in the kidney of deoxycorticosterone acetate-salt hypertensive rats.
    Japanese heart journal, 1996, Volume: 37, Issue:2

    Topics: Animals; Antihypertensive Agents; Captopril; Desoxycorticosterone; Hypertension; Kidney; Kidney Glom

1996
Antihypertensive effects of a new transdermal delivery system for clonidine in genetic and experimental hypertensive rats.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:3

    Topics: Administration, Cutaneous; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blocker

1996
Molecular effects of M17055, furosemide and thiazide on cardiac hypertrophy of spontaneously hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:2

    Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Collagen; Diuretics; Electrolytes; Furosemide; G

1996
Hypotensive effects of a new transdermal delivery system for clonidine (M-5041T) in spontaneously and renal hypertensive rats.
    Clinical and experimental pharmacology & physiology. Supplement, 1995, Volume: 22, Issue:1

    Topics: Administration, Cutaneous; Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; C

1995
Renal effects of the calcium channel blocker aranidipine and its active metabolite in anesthetized dogs and conscious spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:2

    Topics: Administration, Oral; Animals; Blood Pressure; Calcium Channel Blockers; Creatinine; Dihydropyridine

1998
Effects of antihypertensive treatment on platelet function in essential hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23, Issue:6

    Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; bet

2000
Characterization of the antihypertensive effect of a thiazide diuretic in angiotensin II-induced hypertension.
    Journal of hypertension, 2001, Volume: 19, Issue:9

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Administration Sch

2001
[Effects of a beta-adrenolytic and a diuretic vis-à-vis hyper-reninemia induced by isoprenaline in anesthetized dogs. Value of beta blocking-diuretic interaction].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1977, Volume: 171, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Benzopyrans; Dogs; Humans; Hypertension; Isoproterenol; Renin;

1977
Effects of antihypertensive treatment on left ventricular hypertrophy in patients with essential hypertension.
    Journal of the American Geriatrics Society, 1979, Volume: 27, Issue:11

    Topics: Adult; Aged; Animals; Antihypertensive Agents; Cardiomegaly; Electrocardiography; Female; Heart Vent

1979
[Hypotensive effects of diltiazem in DOCA/saline hypertensive rats (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1979, Volume: 75, Issue:2

    Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure

1979
Age-related changes in endocrine and renal function in patients with essential hypertension.
    Journal of the American Geriatrics Society, 1979, Volume: 27, Issue:9

    Topics: Adult; Age Factors; Aged; Blood Pressure; Blood Urea Nitrogen; Creatinine; Female; Humans; Hypertens

1979
[Evaluation of antihypertensive agents for the treatment of mild and intermediate hypertension--results of 4 years of prospective studies].
    Nihon rinsho. Japanese journal of clinical medicine, 1979, Volume: 37, Issue:10

    Topics: Aged; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Trichlormethiazide

1979
Inhibitory effect of trichlormethiazide on development of DOC hypertension in rats.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:5

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Desoxycorticosterone; Diuretics; Elec

1977
Proceedings: Study on the effect of long-term administration (one year) of trichlormethiazide upon glucose metabolism of SHR.
    Japanese heart journal, 1976, Volume: 17, Issue:3

    Topics: Animals; Blood Glucose; Disease Models, Animal; Female; Glucose; Hypertension; Long-Term Care; Male;

1976
[Prolonged clinical study of the LA, 313-B-xanthinol niacinate pentosan sulfonate ester combination in various forms of hypertension].
    Revista clinica espanola, 1976, Jul-31, Volume: 142, Issue:2

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Evaluation; Female; Hu

1976
[Hypertension in the aged. (6) Antihypertensive treatment].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1975, Volume: 12, Issue:4

    Topics: Aged; Female; Humans; Hypertension; Male; Trichlormethiazide

1975
Sinus arrest following diuretic therapy in a patient with myxedema and hypertension.
    Cardiology, 1975, Volume: 60, Issue:3

    Topics: Aged; Female; Heart Arrest; Humans; Hypertension; Myxedema; Trichlormethiazide

1975
Renal arteriolar diameters in spontaneously hypertensive rats. Vascular cast study.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 18, Issue:1

    Topics: Aging; Animals; Arterioles; Blood Pressure; Body Weight; Captopril; Hydralazine; Hypertension; Kidne

1991
Herbal medicine can induce hypertension.
    Nephron, 1991, Volume: 59, Issue:2

    Topics: Adult; Beverages; Blood Pressure; Female; Humans; Hypertension; Phytotherapy; Trichlormethiazide

1991
Chronotherapy of trichlormethiazide in hypertensive patients.
    Journal of clinical pharmacology, 1991, Volume: 31, Issue:1

    Topics: Adult; Aged; Blood Glucose; Blood Pressure; Body Weight; Chlorides; Circadian Rhythm; Female; Heart

1991
[Significance of brain renin for pathogenesis of hypertension: effect of antihypertensive drugs on active and inactive renins in the brain of spontaneously hypertensive rat].
    Nihon Naibunpi Gakkai zasshi, 1989, Jan-20, Volume: 65, Issue:1

    Topics: Animals; Antihypertensive Agents; Atenolol; Blood Pressure; Brain; Captopril; Enzyme Activation; Enz

1989
Effects of thiazide diuretic on vascular eicosanoid system of spontaneously hypertensive rats.
    Journal of hypertension, 1989, Volume: 7, Issue:6

    Topics: Animals; Aorta; Blood Pressure; Body Weight; Cytochrome P-450 Enzyme System; Diuretics; Epoprostenol

1989
Effects of long term oral administration of ketanserin and trichlormethiazide on blood pressure in stroke-prone spontaneously hypertensive rats.
    Drugs, 1988, Volume: 36 Suppl 1

    Topics: Administration, Oral; Animals; Blood Pressure; Cerebrovascular Disorders; Hypertension; Ketanserin;

1988
[Effects of chronic oral administration of ketanserin and trichlormethiazide on blood pressure in stroke-prone spontaneously hypertensive rats].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1988, Volume: 63, Issue:2

    Topics: Administration, Oral; Animals; Blood Pressure; Diuresis; Drug Synergism; Drug Therapy, Combination;

1988
Cough associated with the use of captopril.
    Archives of internal medicine, 1985, Volume: 145, Issue:8

    Topics: Aged; Captopril; Carteolol; Cough; Drug Therapy, Combination; Female; Humans; Hypertension; Methyldo

1985
Depression after treatment with thiazide diuretics for hypertension.
    The American journal of psychiatry, 1985, Volume: 142, Issue:9

    Topics: Adult; Aged; Blood Pressure; Depressive Disorder; Diuretics; Drug Therapy, Combination; Female; Huma

1985
[Problems in the management of mild hypertensive patients following MRFIT].
    Nihon rinsho. Japanese journal of clinical medicine, 1985, Volume: 43, Issue:5

    Topics: Adult; Blood Glucose; Cholesterol; Coronary Disease; Diuretics; Humans; Hypertension; Male; Middle A

1985
[Esmalorid in ambulatory patients with mild to medium severe hypertension. Results of a dosage-titration study].
    Fortschritte der Medizin, 1985, Sep-19, Volume: 103, Issue:35

    Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Trichlormethiaz

1985
[Treatment of arterial hypertension with the hypotensive agent LA-313 B].
    Folia clinica internacional, 1974, Volume: 24, Issue:12

    Topics: Adult; Aged; Antihypertensive Agents; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middl

1974
[The antihypertensive effects of bendroflumethiazide, hydroflumethiazide, trichlormethiazide, chlorthalidone and furosemide].
    Ugeskrift for laeger, 1973, Aug-13, Volume: 135, Issue:33

    Topics: Adult; Aged; Bendroflumethiazide; Chlorthalidone; Diuretics; Female; Furosemide; Humans; Hydroflumet

1973
Role of posture in sodium, water, and potassium homeostasis of an abnormal pregnancy.
    Metabolism: clinical and experimental, 1970, Volume: 19, Issue:8

    Topics: Adolescent; Aminohippuric Acids; Blood Pressure; Creatinine; Diet Therapy; Diuresis; Female; Glomeru

1970
The role of catecholamines in circulatory regulation on the chronic congestive heart failure. Clinical study of the urinary catecholamine excretion in the patients with chronic congestive heart failure.
    Japanese circulation journal, 1968, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Aged; Blood Pressure; Cardiomyopathies; Catecholamines; Coronary Disease; Digital

1968
Thiazide treatment in pregnancy with special reference to maternal and foetal electrolytes.
    Acta obstetricia et gynecologica Scandinavica, 1968, Volume: 47, Issue:4

    Topics: Adolescent; Adult; Blood Chemical Analysis; Chlorides; Diuretics; Edema; Female; Humans; Hydrochloro

1968
[Hypotensive diuretics and abnormalities of carbohydrate metabolism].
    Saishin igaku. Modern medicine, 1969, Volume: 24, Issue:6

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Carbohydrate Metabolism; Chlorthalidone; Gluco

1969
[Thiazide therapy of hypertension and its effect on hyperuricemia].
    Nihon rinsho. Japanese journal of clinical medicine, 1969, Volume: 27, Issue:5

    Topics: Adult; Aged; Blood Pressure; Female; Humans; Hypertension; Male; Methyclothiazide; Middle Aged; Tric

1969
[Effect of trichlormethiazide and triamterene on blood pressure, serum electrolytes and erythrocyte sodium].
    Nordisk medicin, 1966, Sep-08, Volume: 76, Issue:36

    Topics: Electrolytes; Erythrocytes; Female; Humans; Hypertension; Male; Potassium Chloride; Sodium; Triamter

1966