Page last updated: 2024-11-07

trichlorfon and Schistosomiasis

trichlorfon has been researched along with Schistosomiasis in 100 studies

Trichlorfon: An organochlorophosphate cholinesterase inhibitor that is used as an insecticide for the control of flies and roaches. It is also used in anthelmintic compositions for animals. (From Merck, 11th ed)
trichlorfon : A phosphonic ester that is dimethyl phosphonate in which the hydrogen atom attched to the phosphorous is substituted by a 2,2,2-trichloro-1-hydroxyethyl group.

Schistosomiasis: Infection with flukes (trematodes) of the genus SCHISTOSOMA. Three species produce the most frequent clinical diseases: SCHISTOSOMA HAEMATOBIUM (endemic in Africa and the Middle East), SCHISTOSOMA MANSONI (in Egypt, northern and southern Africa, some West Indies islands, northern 2/3 of South America), and SCHISTOSOMA JAPONICUM (in Japan, China, the Philippines, Celebes, Thailand, Laos). S. mansoni is often seen in Puerto Ricans living in the United States.

Research Excerpts

ExcerptRelevanceReference
"Trichlorfon (metrifonate) was given intermittently to 37 schoolboys with urinary schistosomiasis living in a hyperendemic area of the Sudan."7.67Intermittent chemotherapy with trichlorfon (metrifonate) reverses proteinuria, hematuria, and leukocyturia in urinary schistosomiasis: results of a three-year field study. ( Dafalla, AA; Doehring, E; Ehrich, JH; Feldmeier, H; Poggensee, U; Vester, U, 1984)
"Metrifonate (0,0-dimethyl-[1-hydroxy-2,2,2-trichloroethyl]-phosphonate), and its rearrangement product dichlorvos (2,2-dichlorovinyl dimethyl phosphate) (DDVP), were studied in plasma from two patients with schistosomiasis who were treated with Bilarcil."7.66Plasma levels of metrifonate and dichlorvos during treatment of schistosomiasis with bilarcil. ( Bengtsson, E; Finkel, Y; Holmstedt, B; Nordgren, I, 1980)
" Both compounds reach peak levels in blood within two hours after oral dosing and are detectable for at least eight hours."5.26Levels of metrifonate and dichlorvos in plasma and erythrocytes during treatment of schistosomiasis with Bilarcil. ( Bengtsson, E; Holmstedt, B; Nordgren, I; Pettersson, BM, 1981)
"Trichlorfon (metrifonate) was given intermittently to 37 schoolboys with urinary schistosomiasis living in a hyperendemic area of the Sudan."3.67Intermittent chemotherapy with trichlorfon (metrifonate) reverses proteinuria, hematuria, and leukocyturia in urinary schistosomiasis: results of a three-year field study. ( Dafalla, AA; Doehring, E; Ehrich, JH; Feldmeier, H; Poggensee, U; Vester, U, 1984)
"This study was designed to determine the effects of early active schistosomiasis and treatment with antischistosomal agents on concentrations of the oral contraceptive (OC) steroids, ethinyl estradiol and levonorgestrel."3.67Contraceptive steroid concentrations in women with early active schistosomiasis: lack of effect of antischistosomal drugs. ( Back, DJ; el-Raghy, I; Fathalla, M; Orme, ML; Osman, F, 1986)
"Metrifonate (0,0-dimethyl-[1-hydroxy-2,2,2-trichloroethyl]-phosphonate), and its rearrangement product dichlorvos (2,2-dichlorovinyl dimethyl phosphate) (DDVP), were studied in plasma from two patients with schistosomiasis who were treated with Bilarcil."3.66Plasma levels of metrifonate and dichlorvos during treatment of schistosomiasis with bilarcil. ( Bengtsson, E; Finkel, Y; Holmstedt, B; Nordgren, I, 1980)
"hematobium egg counts, heavier hookworm infections, positive Plasmodium slides, and larger spleens."2.66Relationships of Schistosoma hematobium, hookworm and malarial infections and metrifonate treatment to hemoglobin level in Kenyan school children. ( Crompton, DW; Kinoti, SN; Kurz, KM; Latham, MC; Oduori, ML; Stephenson, LS, 1985)
"Praziquantel 40 mg/kg was the most effective drug giving a greater than 97% reduction in egg output six months after treatment; combined treatment with niridazole 25 mg/kg and metrifonate 10 mg/kg gave a reduction of greater than 92% and metrifonate 10 mg/kg alone a reduction of greater than 86%."2.65Single dose oral treatment in urinary schistosomiasis: a double blind trial. ( Pugh, RN; Teesdale, CH, 1983)
"Schistosomiasis is a curable parasitic infection that, if left untreated, can persist for 30 years even though the parasite cannot reproduce in its human host."2.38Schistosomiasis. ( Lucey, DR; Maguire, JH, 1993)
"Praziquantel was the most effective drug; a dose of 100 mg/kg given orally for 5 days resulted in a 95% reduction in worm burdens."1.28Experimental chemotherapy of Schistosoma curassoni in mice. ( Hilderson, H; Rollinson, D; Southgate, VR; Vercruysse, J, 1989)
" haematobium) and dosage schedule, and the third phase as from 1970 on about the use of the product in large groups of patients."1.26Therapeutic properties of metrifonate. ( Snellen, WM, 1981)
" Both compounds reach peak levels in blood within two hours after oral dosing and are detectable for at least eight hours."1.26Levels of metrifonate and dichlorvos in plasma and erythrocytes during treatment of schistosomiasis with Bilarcil. ( Bengtsson, E; Holmstedt, B; Nordgren, I; Pettersson, BM, 1981)
"Determination of the efficacy of mass treatment of schistosomiasis is usually based on the rate of cure."1.26Quantification of infection with Schistosoma haematobium in relation to epidemiology and selective population chemotherapy. II. Mass treatment with a single oral dose of metrifonate. ( Houser, HB; Ouma, JH; Siongok, TK; Warren, KS, 1978)

Research

Studies (100)

TimeframeStudies, this research(%)All Research%
pre-199095 (95.00)18.7374
1990's5 (5.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
LUE, BF1
LIANG, YI1
SHI, JM1
TING, KS1
TALAAT, SM3
AMIN, N1
ELMASRY, B1
Adeiga, AA1
Ade-Serrano, MA2
Maxwell, IC2
Le Quesne, PM2
Ekue, JM1
Biles, JE1
De Cock, KM1
Pugh, RN4
Teesdale, CH4
Chen, MG1
Mason, PR2
Tswana, SA2
Monson, MH1
Alexander, K1
el Kholy, A1
Boutros, S1
Tamara, F1
Warren, KS2
Mahmoud, AA2
Wishahi, MM1
el-Sherbeni, E1
el-Baz, H1
Diallo, S1
Ceccon, JF1
Victorius, A1
Diouf, F1
N'dir, O1
Feldmeier, H6
Stevens, WJ2
Bridts, CH2
Daffalla, AA4
Büttner, DW1
Doehring, E4
Dafalla, AA1
Ehrich, JH1
Vester, U1
Poggensee, U1
Browning, MD1
Narooz, SI1
Strickland, GT1
El-Masry, NA2
Abdel-Wahab, MF1
Webbe, G6
Feldmeir, H1
McMahon, JE1
Daffala, AA1
Omer, AH3
Dietrich, M3
Stephenson, LS4
Kurz, KM3
Latham, MC4
Kinoti, S1
Oduori, ML4
Chitsulo, L1
Mkandawire, AC1
Disko, R1
McNeeley, DF1
Habib, MA1
El Alamy, MA1
Cline, BL1
Bushara, HO1
Hussein, MF1
Majid, MA1
Taylor, MG1
Druilhe, P1
Bourdillon, F1
Froment, A1
Kyelem, JM1
Wilkins, HA1
Moore, PJ1
Rugemalila, JB2
Eyakuze, VM1
Gilles, HM3
Ejezie, GC1
Farid, Z1
Bassily, S1
Kilpatrick, ME1
Watten, RH1
Trabolsi, B1
Brunzema, F1
Bloom, A1
Snellen, WM1
Jewsbury, JM4
Nordgren, I2
Bengtsson, E2
Holmstedt, B2
Pettersson, BM1
Finkel, Y1
Xu, RK1
Lucey, DR1
Maguire, JH1
Coulaud, JP2
Charmot, G1
Giacobini, E1
Taylor, P1
Chatelain, C1
Payet, M1
Bienzle, U1
Sievertsen, HJ1
Onadeko, MO1
Fleischer, NK1
Saif, M1
Gaber, A1
Hassanein, YS1
Khameis, S1
Jamnadas, VP1
Thomas, JE1
El-Kabbaj, M1
Hassar, M1
Gelfand, M1
Blair, DM1
James, MF1
Siongok, TK1
Ouma, JH1
Houser, HB1
Hatchuel, W1
Hsiao, SH2
Liu, JC2
Chan, CC2
Pereira, LH1
Pellegrino, J1
Mello, RT1
Cooke, MJ2
Weber, MC1
Haas, J1
Hansen, G1
Jarrett, B1
Oomen, JM1
Bell, DR2
Reddy, S1
Niemandt, S1
Murahwa, S1
Davis, A2
el-Hawey, AM1
Massoud, AM1
el-Rakieby, A1
Royzeik, MS1
Nassar, MO1
Vercruysse, J1
Southgate, VR1
Rollinson, D1
Hilderson, H1
el-Raghy, I1
Back, DJ1
Osman, F1
Orme, ML1
Fathalla, M1
Sabatier, P1
Delatre, M1
Le Bras, J1
Vicens, R1
Coulanges, P1
Archer, S1
Kinoti, SN3
Miller, D1
Kitron, UD1
Higashi, GI1
Crompton, DW1
Asila, J1
Chimbe, A1
Degrémont, A1
Koura, M1
James, C3
Van Wyk, JA1
Bartsch, RC1
Van Rensburg, LJ1
Heitmann, LP1
Goosen, PJ1
James, G1
Davis, RP1
Bailey, DR1
Preston, JM2
Bueding, E1
Liu, CL1
Rogers, SH1
Forsyth, DM1

Reviews

8 reviews available for trichlorfon and Schistosomiasis

ArticleYear
Human schistosomiasis and its management.
    The Journal of infection, 1984, Volume: 8, Issue:1

    Topics: Animals; Humans; Hycanthone; Oxamniquine; Praziquantel; Schistosoma; Schistosomiasis; Trichlorfon

1984
Schistosomiasis: clinical features and relevance to hematology.
    Seminars in hematology, 1982, Volume: 19, Issue:2

    Topics: Anemia; Animals; Blood Coagulation Disorders; Eosinophilia; Humans; Mice; Niridazole; Oxamniquine; P

1982
Schistosomiasis.
    Infectious disease clinics of North America, 1993, Volume: 7, Issue:3

    Topics: Adult; Animals; Female; Hepatitis B; HIV Infections; Humans; Male; Neoplasms; Oxamniquine; Praziquan

1993
Metrifonate. A viewpoint.
    Drugs & aging, 1997, Volume: 11, Issue:6

    Topics: Acetylcholine; Alzheimer Disease; Animals; Anthelmintics; Cerebral Cortex; Cholinesterase Inhibitors

1997
[Urogenital bilharziasis].
    Journal d'urologie et de nephrologie, 1977, Volume: 83 Suppl 1

    Topics: Animals; Antimony; Emetine; Female; Genital Diseases, Female; Genital Diseases, Male; Humans; Male;

1977
[Central nervous system involvement in parasitic tropical diseases].
    Die Medizinische Welt, 1979, Nov-02, Volume: 30, Issue:44

    Topics: Adult; Blood-Brain Barrier; Central Nervous System Diseases; Cysticercosis; Female; Hartmannella; Hu

1979
Recent advances in schistosomiasis.
    The Quarterly journal of medicine, 1986, Volume: 58, Issue:226

    Topics: Adolescent; Child; Humans; Oxamniquine; Parasite Egg Count; Praziquantel; Schistosomiasis; Serologic

1986
The chemotherapy of schistosomiasis.
    Annual review of pharmacology and toxicology, 1985, Volume: 25

    Topics: Animals; Chemical Phenomena; Chemistry; Diphenylamine; Humans; Hycanthone; Isothiocyanates; Niridazo

1985

Trials

12 trials available for trichlorfon and Schistosomiasis

ArticleYear
Long-term efficacy of single-dose oral treatment in schistosomiasis haematobium.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1984, Volume: 78, Issue:1

    Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Me

1984
Single dose oral treatment in urinary schistosomiasis: a double blind trial.
    British medical journal (Clinical research ed.), 1983, Feb-05, Volume: 286, Issue:6363

    Topics: Administration, Oral; Adolescent; Child; Clinical Trials as Topic; Double-Blind Method; Drug Combina

1983
A comparative trial of praziquantel, metrifonate and niridazole against Schistosoma haematobium.
    Annals of tropical medicine and parasitology, 1983, Volume: 77, Issue:2

    Topics: Humans; Isoquinolines; Niridazole; Praziquantel; Random Allocation; Schistosoma haematobium; Schisto

1983
Concurrent dosage with niridazole and metrifonate for the treatment of Bilharziasis in school children in Malawi.
    The Central African journal of medicine, 1980, Volume: 26, Issue:9

    Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Ma

1980
Efficacy of metrifonate in urinary schistosomiasis in light and heavy infections.
    Tropenmedizin und Parasitologie, 1982, Volume: 33, Issue:2

    Topics: Adult; Child; Clinical Trials as Topic; Humans; Male; Parasite Egg Count; Prospective Studies; Schis

1982
Metrifonate trial in the treatment of various presentations of Schistosoma haematobium and S. mansoni infections in the Sudan.
    Annals of tropical medicine and parasitology, 1978, Volume: 72, Issue:2

    Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Feces; Female; Humans; Intestinal Diseases, Para

1978
Efficacy of oxamniquine in treatment of S. mansoni in a closed community in Egypt and the concomitant administration of both metrifonate and oxamniquine in mixed infections.
    The Journal of the Egyptian Medical Association, 1978, Volume: 61, Issue:5-6

    Topics: Adult; Clinical Trials as Topic; Drug Therapy, Combination; Egypt; Humans; Male; Nitroquinolines; Ox

1978
Field trial of metrifonate in the treatment and prevention of schistosomiasis infection in man.
    Annals of tropical medicine and parasitology, 1977, Volume: 71, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Cholinesterases; Female; Humans; Male; Schistosoma haematobium;

1977
Prophylaxis of schistosomiasis - field trial of metrifonate for the prevention of human infection.
    Annals of tropical medicine and parasitology, 1976, Volume: 70, Issue:3

    Topics: Female; Humans; Male; Schistosoma haematobium; Schistosomiasis; Trichlorfon

1976
Metrifonate in urinary schistosomiasis. A field trial in northern Nigeria.
    Annals of tropical medicine and parasitology, 1975, Volume: 69, Issue:1

    Topics: Administration, Oral; Adolescent; Child; Clinical Trials as Topic; Drug Evaluation; Female; Follow-U

1975
Study of some aspects of cell mediated immune response in bilharzial children on a field level.
    Journal of the Egyptian Society of Parasitology, 1991, Volume: 21, Issue:2

    Topics: Adolescent; Child; Drug Therapy, Combination; Humans; Immunity, Cellular; Phagocytosis; Praziquantel

1991
Relationships of Schistosoma hematobium, hookworm and malarial infections and metrifonate treatment to hemoglobin level in Kenyan school children.
    The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:3

    Topics: Adolescent; Anemia; Child; Feces; Female; Hemoglobins; Hookworm Infections; Humans; Kenya; Malaria;

1985

Other Studies

80 other studies available for trichlorfon and Schistosomiasis

ArticleYear
[STUDIES ON ANTIBILHARZIAL DRUGS. XXVIII. TOXICITY AND EXPERIMENTAL THERAPY FOR SCHISTOSOMIASIS JAPONICA OF DIPTEREX].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1962, Volume: 9

    Topics: Antiprotozoal Agents; Dogs; Mice; Organophosphate Poisoning; Pharmacology; Phosphorus; Poisons; Rabb

1962
THE TREATMENT OF BILHARZIASIS AND OTHER INTESTINAL PARASITES WITH DIPTEREX. A PRELIMINARY REPORT ON ONE HUNDRED CASES.
    The Journal of the Egyptian Medical Association, 1963, Volume: 46

    Topics: Animals; Anthelmintics; Ascariasis; Enterobius; Hookworm Infections; Humans; Intestinal Diseases, Pa

1963
A FURTHER REPORT ON THE TREATMENT OF SCHISTOSOMIASIS WITH DIPTEREX USING 10MG./KG. BODY WEIGHT FOR SIX DOSES.
    The Journal of the Egyptian Medical Association, 1964, Volume: 47

    Topics: Antiprotozoal Agents; Body Weight; Body Weights and Measures; Drug Therapy; Phosphates; Research; Sc

1964
DIPTEREX: AN ORAL THERAPEUTIC AGENT IN THE TREATMENT OF SCHISTOSOMIASIS AND OTHER INTESTINAL PARASITES.
    The Journal of the Egyptian Medical Association, 1964, Volume: 47

    Topics: Animals; Drug Therapy; Insecticides; Intestinal Diseases; Intestinal Diseases, Parasitic; Parasites;

1964
Cryoglobulins in Schistosoma haematobium infection.
    Acta tropica, 1983, Volume: 40, Issue:2

    Topics: Adolescent; Child; Cryoglobulinemia; Cryoglobulins; Humans; Schistosoma haematobium; Schistosomiasis

1983
Effect on neuromuscular transmission of repeated administration of an organophosphorus compound, metrifonate, during treatment of children with urinary schistosomiasis.
    Neurotoxicology, 1981, Volume: 2, Issue:4

    Topics: Action Potentials; Adolescent; Child; Cholinesterases; Female; Humans; Male; Muscles; Neuromuscular

1981
Effect of metrifonate on neuromuscular transmission.
    Acta pharmacologica et toxicologica, 1981, Volume: 49 Suppl 5

    Topics: Action Potentials; Child; Cholinesterase Inhibitors; Cholinesterases; Erythrocytes; Humans; Muscles;

1981
[Studies on fuvinazole-dipterex combination in treatment for schistosomiasis in 318 cases (author's transl)].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1980, Volume: 2, Issue:3

    Topics: Drug Combinations; Female; Humans; Male; Nitrofurans; Schistosomiasis; Schistosomicides; Trichlorfon

1980
Single-dose metrifonate for the treatment of Schistosoma haematobium infection in an endemic area of Zimbabwe.
    The American journal of tropical medicine and hygiene, 1984, Volume: 33, Issue:4

    Topics: Adolescent; Child; Humans; Parasite Egg Count; Schistosoma haematobium; Schistosomiasis; Trichlorfon

1984
Metrifonate in pregnancy.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1984, Volume: 78, Issue:4

    Topics: Abnormalities, Drug-Induced; Female; Humans; Pregnancy; Pregnancy Complications, Infectious; Schisto

1984
The effect of a single dose of metrifonate on Schistosoma haematobium infection in Egyptian school children.
    The American journal of tropical medicine and hygiene, 1984, Volume: 33, Issue:6

    Topics: Child; Egypt; Humans; Parasite Egg Count; Schistosoma haematobium; Schistosomiasis; Trichlorfon

1984
Granulomatous cystitis: a reversible lesion in children.
    European urology, 1984, Volume: 10, Issue:6

    Topics: Adolescent; Antibody-Coated Bacteria Test, Urinary; Child; Cystitis; Granuloma; Humans; Male; Schist

1984
[Effectiveness of 3 doses of metrifonate in the treatment of urinary bilharziasis in Senegal].
    Dakar medical, 1983, Volume: 28, Issue:1

    Topics: Adolescent; Child; Female; Humans; Male; Schistosoma haematobium; Schistosomiasis; Time Factors; Tri

1983
Effect of chemotherapy and reinfection on IgE-containing and IgG-containing circulating immune complexes, serum IgE and IgE antibodies in patients chronically infected with Schistosoma mansoni and Schistosoma haematobium.
    International archives of allergy and applied immunology, 1983, Volume: 72, Issue:3

    Topics: Antigen-Antibody Complex; Child; Humans; Immunoglobulin E; Immunoglobulin G; Male; Parasite Egg Coun

1983
Intermittent chemotherapy with trichlorfon (metrifonate) reverses proteinuria, hematuria, and leukocyturia in urinary schistosomiasis: results of a three-year field study.
    The Journal of infectious diseases, 1984, Volume: 149, Issue:4

    Topics: Child; Drug Administration Schedule; Hematocrit; Hematuria; Humans; Leukocytes; Male; Parasite Egg C

1984
Clinical characteristics and response to therapy in Egyptian children infected with Schistosoma haematobium.
    The Journal of infectious diseases, 1984, Volume: 149, Issue:6

    Topics: Adolescent; Blood Cell Count; Egypt; Female; Follow-Up Studies; Hematuria; Hepatitis A; Hepatitis B;

1984
The six diseases of WHO. Schistosomiasis: some advances.
    British medical journal (Clinical research ed.), 1981, Oct-24, Volume: 283, Issue:6299

    Topics: Humans; Molluscacides; Oxamniquine; Praziquantel; Schistosomiasis; Snails; Trichlorfon

1981
IgG and IgE circulating immune complexes, total serum IgE and parasite related IgE in patients with mono- or mixed infection with Schistosoma mansoni and/or S. haematobium. Influence of therapy.
    Clinical and experimental immunology, 1983, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Antibody Specificity; Antigen-Antibody Complex; Antigens; Child; Cross Reactions;

1983
Efficacy of metrifonate in urinary schistosomiasis: comparison of reduction of Schistosoma haematobium and S. mansoni eggs.
    The American journal of tropical medicine and hygiene, 1982, Volume: 31, Issue:6

    Topics: Animals; Child; Dose-Response Relationship, Drug; Feces; Female; Humans; Male; Ovum; Parasite Egg Co

1982
The effect of metrifonate on hookworm infections in Kenyan children treated for urinary schistosomiasis. A preliminary report.
    East African medical journal, 1982, Volume: 59, Issue:10

    Topics: Ancylostomatoidea; Child; Feces; Hookworm Infections; Humans; Kenya; Parasite Egg Count; Schistosomi

1982
[Schistosomiasis. Problems and successes].
    Fortschritte der Medizin, 1982, May-06, Volume: 100, Issue:17

    Topics: Communicable Disease Control; Egypt; Humans; Molluscacides; Oxamniquine; Praziquantel; Schistosomias

1982
Patterns of antischistosomal drug usage in Qalyubia Governorate of the Nile Delta.
    The American journal of tropical medicine and hygiene, 1982, Volume: 31, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Drug Utilization; Egypt; Female; H

1982
Simultaneous use of a sensitive filtration technique and reagent strips in urinary schistosomiasis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1982, Volume: 76, Issue:3

    Topics: Child; Filtration; Humans; Male; Parasite Egg Count; Reagent Strips; Schistosoma haematobium; Schist

1982
Effects of praziquantel and metrifonate on Schistosoma bovis infections in Sudanese cattle.
    Research in veterinary science, 1982, Volume: 33, Issue:1

    Topics: Animals; Cattle; Cattle Diseases; Feces; Isoquinolines; Parasite Egg Count; Praziquantel; Schistosom

1982
[Control of urinary schistosomiasis by 3 annual courses of metrifonate].
    Annales de la Societe belge de medecine tropicale, 1981, Volume: 61, Issue:1

    Topics: Adolescent; Animals; Burkina Faso; Child; Child, Preschool; Female; Humans; Male; Schistosoma haemat

1981
Single dose use of metrifonate.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1980, Volume: 74, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Drug Administration Schedule; Follow-Up Studies; Gambia;

1980
Use of metrifonate for selective population chemotherapy against urinary schistosomiasis in an endemic area at Mwanza, Tanzania.
    East African medical journal, 1981, Volume: 58, Issue:1

    Topics: Humans; Schistosoma haematobium; Schistosomiasis; Schistosomicides; Tanzania; Trichlorfon; Urinary T

1981
The treatment of schistosomiasis.
    The Journal of antimicrobial chemotherapy, 1981, Volume: 7, Issue:2

    Topics: Humans; Hycanthone; Niridazole; Oxamniquine; Praziquantel; Schistosomiasis; Trichlorfon

1981
Schistosoma haematobium in Ajara community of Badagry. Metrifonate trials in the treatment of the disease.
    Tropical and geographical medicine, 1981, Volume: 33, Issue:2

    Topics: Adolescent; Child; Female; Humans; Male; Nigeria; Parasite Egg Count; Schistosoma haematobium; Schis

1981
Urinary schistosomiasis in Egyptian farmers treated with metrifonate (Bilarcil).
    Annals of tropical medicine and parasitology, 1981, Volume: 75, Issue:4

    Topics: Adolescent; Child; Drug Administration Schedule; Egypt; Humans; Male; Parasite Egg Count; Schistosom

1981
[The modern treatment of bladder bilharziasis].
    Zeitschrift fur Urologie und Nephrologie, 1981, Volume: 74, Issue:11

    Topics: Drug Administration Schedule; Humans; Niridazole; Praziquantel; Schistosomiasis; Schistosomicides; T

1981
Studies of the mode of action of metrifonate and DDVP in schistosomes - cholinesterase activity and the hepatic shift.
    Acta pharmacologica et toxicologica, 1981, Volume: 49 Suppl 5

    Topics: Animals; Cholinesterases; Cricetinae; Dichlorvos; Liver; Male; Mesocricetus; Schistosoma mansoni; Sc

1981
Therapeutic properties of metrifonate.
    Acta pharmacologica et toxicologica, 1981, Volume: 49 Suppl 5

    Topics: Humans; Schistosoma haematobium; Schistosomiasis; Snails; Trichlorfon

1981
Metrifonate in schistosomiasis - therapy and prophylaxis.
    Acta pharmacologica et toxicologica, 1981, Volume: 49 Suppl 5

    Topics: Animals; Cholinesterases; Humans; Schistosoma haematobium; Schistosomiasis; Time Factors; Trichlorfo

1981
Levels of metrifonate and dichlorvos in plasma and erythrocytes during treatment of schistosomiasis with Bilarcil.
    Acta pharmacologica et toxicologica, 1981, Volume: 49 Suppl 5

    Topics: Adolescent; Child; Cholinesterases; Dichlorvos; Erythrocytes; Female; Half-Life; Humans; Kinetics; M

1981
Plasma levels of metrifonate and dichlorvos during treatment of schistosomiasis with bilarcil.
    The American journal of tropical medicine and hygiene, 1980, Volume: 29, Issue:3

    Topics: Adult; Biotransformation; Dichlorvos; Humans; Male; Schistosoma haematobium; Schistosomiasis; Trichl

1980
[Treatment of schistosomiasis with furan-propylamine and dipterex--its reaction, effectiveness and evaluation (author's transl)].
    Zhonghua nei ke za zhi, 1980, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Drug Evaluation; Drug Therapy, Combination; Female; Furans; Humans;

1980
[Treatment of bilharziasis].
    La Revue du praticien, 1993, Feb-15, Volume: 43, Issue:4

    Topics: Humans; Mass Screening; Niridazole; Oxamniquine; Praziquantel; Schistosomiasis; Trichlorfon

1993
Metrifonate. A viewpoint.
    Drugs & aging, 1997, Volume: 11, Issue:6

    Topics: Alzheimer Disease; Anthelmintics; Binding Sites; Cholinesterase Inhibitors; Humans; Schistosomiasis;

1997
[Specific treatment of urinary bilharziasis].
    Journal d'urologie et de nephrologie, 1977, Volume: 83 Suppl 2

    Topics: Drug Tolerance; Emetine; Humans; Hycanthone; Niridazole; Schistosomiasis; Schistosomicides; Trichlor

1977
Combination of a viability test and a quantification method for Schistosoma haematobium eggs (filtration--trypan blue-staining-technique).
    Tropenmedizin und Parasitologie, 1979, Volume: 30, Issue:4

    Topics: Filtration; Humans; Larva; Parasite Egg Count; Schistosoma haematobium; Schistosomiasis; Staining an

1979
Preliminary report on long term cure of schistosomiasis using metrifonate (Bilarcil/Dipterex)--a new antischistosomal drug.
    West African journal of pharmacology and drug research, 1979, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Child; Follow-Up Studies; Humans; Long-Term Care; Niridazole; Schistosomiasis; Sc

1979
Report of the American Schistosomiasis Delegation to the People's Republic of China.
    The American journal of tropical medicine and hygiene, 1977, Volume: 26, Issue:3

    Topics: Amino Acids, Diamino; Animals; Antimony; China; Disease Reservoirs; Drug Evaluation; Drug Evaluation

1977
Combined oral furapromidum and rectal dipterex in schistosomiasis japonica.
    Chinese medical journal, 1977, Volume: 3, Issue:2

    Topics: Acrylamides; Administration, Oral; Drug Therapy, Combination; Female; Humans; Male; Nitrofurans; Sch

1977
Metriphonate and organophosphate poisoning.
    The Central African journal of medicine, 1979, Volume: 25, Issue:6

    Topics: Child; Humans; Male; Schistosomiasis; Trichlorfon

1979
Malumfashi Endemic Disease Research Project, VIII. Follow-up intravenous urograms of boys infected with Schistosoma haematobium from the Malumfashi area.
    Annals of tropical medicine and parasitology, 1979, Volume: 73, Issue:2

    Topics: Adolescent; Child; Follow-Up Studies; Humans; Male; Nigeria; Schistosoma haematobium; Schistosomiasi

1979
[Medical treatment of urogenital bilharziasis].
    al-Maghrib al-tibbi. Maroc medical, 1979, Volume: 1, Issue:3

    Topics: Antimony; Humans; Hycanthone; Niridazole; Schistosomiasis; Schistosomicides; Trichlorfon

1979
Significant advances in the management of bilharziasis.
    The Central African journal of medicine, 1977, Volume: 23, Issue:11 Suppl

    Topics: Humans; Nitroquinolines; Oxamniquine; Schistosomiasis; Trichlorfon

1977
Treatment of bilharziasis due to Schistosoma haematobium infection.
    The Central African journal of medicine, 1977, Volume: 23, Issue:11 Suppl

    Topics: Administration, Oral; Humans; Oxamniquine; Schistosoma haematobium; Schistosomiasis; Schistosomicide

1977
Schistosomiasis, metriphonate, cholinesterase, and suxamethonium.
    British medical journal, 1978, Feb-18, Volume: 1, Issue:6110

    Topics: Cholinesterases; Humans; Schistosomiasis; Succinylcholine; Trichlorfon; Urinary Tract Infections

1978
Malumfashi Endemic Diseases Research Project, V. Concurrent single dose metrifonate and niridazole in urinary schistosomiasis.
    Annals of tropical medicine and parasitology, 1978, Volume: 72, Issue:5

    Topics: Adolescent; Child; Humans; Male; Nigeria; Niridazole; Schistosomiasis; Trichlorfon; Urinary Tract In

1978
Quantification of infection with Schistosoma haematobium in relation to epidemiology and selective population chemotherapy. II. Mass treatment with a single oral dose of metrifonate.
    The Journal of infectious diseases, 1978, Volume: 138, Issue:6

    Topics: Administration, Oral; Adolescent; Child; Drug Administration Schedule; Drug Evaluation; Humans; Keny

1978
Fatal hepatic necrosis in association with hycanthone.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Nov-11, Volume: 54, Issue:20

    Topics: Chemical and Drug Induced Liver Injury; Humans; Hycanthone; Necrosis; Nitroquinolines; Oxamniquine;

1978
Combined oral F30066 and rectal dipterex in treatment of experimental schistosomiasis Japonica.
    Chinese medical journal, 1975, Volume: 1, Issue:1

    Topics: Acrylamides; Administration, Oral; Animals; Drug Therapy, Combination; Nitrofurans; Rabbits; Schisto

1975
Activity of known antischistosomal agents on early-developing forms of Schistosoma mansoni.
    The Journal of parasitology, 1975, Volume: 61, Issue:2

    Topics: Animals; Antimony; Diethylamines; Edetic Acid; Hycanthone; Lithium; Lucanthone; Mice; Oxamniquine; S

1975
[Treatment of schistosomiasis haematobium with metritionate in OPD-patients (author's transl)].
    Immunitat und Infektion, 1976, Volume: 4, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Ambulatory Care; Child; Child, Preschool; Female; Humans; L

1976
Letter: Metrifonate in the treatment of urinary bilharziasis.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1975, Oct-25, Volume: 49, Issue:45

    Topics: Adolescent; Child; Humans; Schistosoma haematobium; Schistosomiasis; Trichlorfon

1975
Clinically available antischistosomal drugs.
    Journal of toxicology and environmental health, 1975, Volume: 1, Issue:2

    Topics: Antimony; Humans; Hycanthone; Lucanthone; Niridazole; Schistosomiasis; Schistosomicides; Trichlorfon

1975
Experimental chemotherapy of Schistosoma curassoni in mice.
    Parasitology research, 1989, Volume: 75, Issue:7

    Topics: Animals; Disease Models, Animal; Female; Hycanthone; Male; Mice; Nitroquinolines; Oxamniquine; Prazi

1989
Contraceptive steroid concentrations in women with early active schistosomiasis: lack of effect of antischistosomal drugs.
    Contraception, 1986, Volume: 33, Issue:4

    Topics: Adolescent; Adult; Drug Interactions; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Norgestrel;

1986
[Serodiagnosis of bilharziasis by indirect ELISA reaction].
    Archives de l'Institut Pasteur de Madagascar, 1986, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Enzyme-Linked Immunosorbent Assay; Humans; Schistosomiasis; Schistosomiasis haema

1986
Report of an independent evaluation mission on the National Bilharzia Control Program, Egypt, 1985 (abridged version).
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1987, Volume: 81 Suppl

    Topics: Animals; Costs and Cost Analysis; Disease Vectors; Egypt; Government Agencies; Humans; Molluscacides

1987
Treatment of schistosomiasis.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:5

    Topics: Humans; Nitroquinolines; Oxamniquine; Praziquantel; Schistosomiasis; Trichlorfon

1987
The chemotherapy of schistosomiasis control.
    Bulletin of the Pan American Health Organization, 1986, Volume: 20, Issue:1

    Topics: Child; Humans; Oxamniquine; Praziquantel; Schistosomiasis; Schistosomicides; Trichlorfon

1986
Regression of splenomegaly and hepatomegaly in children treated for Schistosoma haematobium infection.
    The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Feces; Female; Hepatomegaly; Humans; Kenya; Mal

1985
Urinary iron loss and physical fitness of Kenyan children with urinary schistosomiasis.
    The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:2

    Topics: Child; Female; Humans; Iron; Male; Parasite Egg Count; Physical Fitness; Schistosoma haematobium; Sc

1985
Schistosoma haematobium in Upper Egypt: analysis of dispersion patterns.
    The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:2

    Topics: Adolescent; Child; Egypt; Host-Parasite Interactions; Humans; Male; Parasite Egg Count; Schistosoma

1985
Eighteen-month follow-up on the treatment of urinary schistosomiasis with a single dose of metrifonate.
    The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:4

    Topics: Parasite Egg Count; Schistosomiasis; Time Factors; Trichlorfon; Urine

1985
Schistosomiasis haematobium and the mortality occurring in an endemic community at Bujashi, Tanzania.
    Tropical and geographical medicine, 1985, Volume: 37, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Infant; Male; Middle Aged; Schisto

1985
[Experimental studies on the treatment of schistosomiasis japonica with oral F30066 and rectal dipterex].
    Zhonghua yi xue za zhi, 1973, Volume: 7

    Topics: Administration, Oral; Animals; Ferricyanides; Insecticides; Rabbits; Schistosomiasis; Schistosomicid

1973
[New methods of treatment of schistosomiasis].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1974, Dec-17, Volume: 63, Issue:50

    Topics: Administration, Oral; Ethylenediamines; Injections, Intramuscular; Niridazole; Schistosomiasis; Schi

1974
Lung-shift effect of metrifonate (trichlorofone) in mice infected with Schistosoma mansoni in relation to the duration of infection.
    Annals of tropical medicine and parasitology, 1974, Volume: 68, Issue:3

    Topics: Animals; Drug Evaluation, Preclinical; Female; Lung; Male; Mice; Schistosoma mansoni; Schistosomiasi

1974
The susceptibility of Schistosoma japonicum in hamsters to metrifonate.
    Annals of tropical medicine and parasitology, 1974, Volume: 68, Issue:4

    Topics: Animals; Cholinesterase Inhibitors; Cricetinae; Drug Evaluation, Preclinical; Female; Male; Schistos

1974
Studies on schistosomiasis. 6. A field outbreak of bilharzia in cattle.
    The Onderstepoort journal of veterinary research, 1974, Volume: 41, Issue:2

    Topics: Animals; Bulinus; Cattle; Cattle Diseases; Digestive System; Disease Outbreaks; Liver; Schistosomias

1974
Letter: Treatment of Schistosoma Haematobium in the baboon with metrifonate.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1974, Volume: 68, Issue:5

    Topics: Animals; Feces; Liver; Lung; Papio; Parasite Egg Count; Schistosoma haematobium; Schistosomiasis; Tr

1974
Effect of metrifonate on blood cholinesterases in children during the treatment of schistosomiasis.
    Bulletin of the World Health Organization, 1972, Volume: 46, Issue:6

    Topics: Adolescent; Anthelmintics; Child; Cholinesterase Inhibitors; Cholinesterases; Erythrocytes; Female;

1972
A comparison of the susceptibility to metrifonate of Schistosoma haematobium, S. mattheei and S. mansoni in hamsters.
    Annals of tropical medicine and parasitology, 1972, Volume: 66, Issue:4

    Topics: Animals; Capillaries; Cricetinae; Insecticides; Liver; Lung; Mesenteric Veins; Niridazole; Schistoso

1972
Inhibition by metrifonate and dichlorvos of cholinesterases in schistosomes.
    British journal of pharmacology, 1972, Volume: 46, Issue:3

    Topics: Animals; Anthelmintics; Cholinesterase Inhibitors; Cricetinae; Dichlorvos; Female; Insecticides; Mal

1972
Treatment of urinary schistosomiasis.
    British medical journal, 1972, Feb-12, Volume: 1, Issue:5797

    Topics: Humans; Organophosphorus Compounds; Schistosomiasis; Trichlorfon; Urinary Tract Infections

1972
The action of metrifonate on 3 species of schistosomes.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1972, Volume: 66, Issue:4

    Topics: Animals; Cricetinae; Insecticides; Schistosoma; Schistosoma haematobium; Schistosoma mansoni; Schist

1972