trichlorfon has been researched along with Pregnancy in 39 studies
Trichlorfon: An organochlorophosphate cholinesterase inhibitor that is used as an insecticide for the control of flies and roaches. It is also used in anthelmintic compositions for animals. (From Merck, 11th ed)
trichlorfon : A phosphonic ester that is dimethyl phosphonate in which the hydrogen atom attched to the phosphorous is substituted by a 2,2,2-trichloro-1-hydroxyethyl group.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " (metrifonate, trichlorfon) during pregnancy." | 7.66 | Congenital ataxia and tremor with cerebellar hypoplasia in piglets borne by sows treated with Neguvon vet. (metrifonate, trichlorfon) during pregnancy. ( Askaa, J; Basse, A; Bitsch, V; Eskildsen, M; Knox, B; Mandrup, M; Ottosen, HE; Overby, E; Pedersen, KB; Rasmussen, F, 1978) |
| " (metrifonate, trichlorfon) during pregnancy." | 3.66 | Congenital ataxia and tremor with cerebellar hypoplasia in piglets borne by sows treated with Neguvon vet. (metrifonate, trichlorfon) during pregnancy. ( Askaa, J; Basse, A; Bitsch, V; Eskildsen, M; Knox, B; Mandrup, M; Ottosen, HE; Overby, E; Pedersen, KB; Rasmussen, F, 1978) |
| " Dosing with 0." | 2.66 | Efficacy of an oxibendazole-trichlorfon paste formulation against third stage larvae of Gasterophilus intestinalis and its safety in horses. ( Bauer, C; Bürger, HJ, 1986) |
| "Trichlorfon is a widely used broad-spectrum agricultural insecticide." | 1.37 | Effects of repeated maternal oral exposure to low levels of trichlorfon on development and cytogenetic toxicity in 3-day mouse embryos. ( Ding, Y; Gao, Y; Han, S; Heiger-Bernays, W; Shen, X; Shi, R; Tian, Y; Wang, P; Zhou, S; Zhou, Y, 2011) |
| "Trichlorfon has been widely used in agriculture as a broad spectrum insecticide." | 1.31 | Analysis of cytogenetic and developmental effects on pre-implantation, mid-gestation and near-term mouse embryos after treatment with trichlorfon during zygote stage. ( Ishikawa, H; Tian, Y; Yamauchi, T, 2000) |
| " In the first case, for example, the Ministry of Health changed the policy of using high oestrogens dosage (which increased the risk of this defect 6." | 1.30 | Using the Hungarian Birth Defects Registry for surveillance, research and intervention. ( Czeizel, AE; Siffel, C, 1997) |
| " At the same dosage level, the hemiacetal proved to be ineffective in the micronucleus test on fetal blood of DBA and AB Jena/Halle mice." | 1.27 | Cytogenetic, genetic, and embryotoxicity studies with dimethyl 2,2,2-trichloro-1-(2,2,2-trichloro-1-hydroxyethoxy)-ethylphosphonat e, a hypothetical impurity in technical grade trichlorfon. ( Fischer, GW; Huszta, E; Mazzag, E; Nehéz, M; Scheufler, H; Schneider, P, 1987) |
| "Trichlorfon was evaluated for its teratogenic potential in the CD-1 mouse at doses of 200, 300 or 400 mg/kg/day administered by gavage on days 7-16 of gestation." | 1.27 | Assessment of teratogenic potential of trichlorfon in mice and rats. ( Andrews, JE; Courtney, KD; Springer, J, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (71.79) | 18.7374 |
| 1990's | 5 (12.82) | 18.2507 |
| 2000's | 4 (10.26) | 29.6817 |
| 2010's | 2 (5.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lim, W | 1 |
| An, Y | 1 |
| Yang, C | 1 |
| Bazer, FW | 1 |
| Song, G | 1 |
| Tian, Y | 3 |
| Dai, F | 1 |
| Shen, L | 1 |
| Feng, Y | 1 |
| Gao, Y | 2 |
| Xu, L | 1 |
| Han, S | 2 |
| Shen, X | 2 |
| Zhou, S | 1 |
| Zhou, Y | 1 |
| Shi, R | 1 |
| Heiger-Bernays, W | 1 |
| Ding, Y | 1 |
| Wang, P | 1 |
| Mehl, A | 1 |
| Schanke, TM | 1 |
| Torvik, A | 1 |
| Fonnum, F | 5 |
| Grabowski, CT | 1 |
| Monson, MH | 1 |
| Alexander, K | 1 |
| Fatzer, R | 1 |
| Häni, H | 1 |
| Scholl, E | 1 |
| Belchev, L | 1 |
| Khristov, T | 1 |
| Chifudov, D | 1 |
| Moutschen-Dahmen, J | 1 |
| Moutschen-Dahmen, M | 1 |
| Degraeve, N | 1 |
| Czeizel, AE | 3 |
| Elek, C | 1 |
| Gundy, S | 1 |
| Métneki, J | 1 |
| Nemes, E | 1 |
| Reis, A | 1 |
| Sperling, K | 1 |
| Tímár, L | 1 |
| Tusnády, G | 1 |
| Virágh, Z | 1 |
| Siffel, C | 1 |
| Kusel, J | 1 |
| Hagan, P | 1 |
| Lock, EA | 1 |
| Ishikawa, H | 1 |
| Yamauchi, T | 1 |
| Morrow, GL | 1 |
| Staples, RE | 1 |
| Goulding, EH | 1 |
| Martson', LV | 1 |
| Knox, B | 1 |
| Askaa, J | 1 |
| Basse, A | 1 |
| Bitsch, V | 1 |
| Eskildsen, M | 1 |
| Mandrup, M | 1 |
| Ottosen, HE | 1 |
| Overby, E | 1 |
| Pedersen, KB | 1 |
| Rasmussen, F | 1 |
| Kozaczenko, J | 1 |
| Dobson, KJ | 1 |
| Scheufler, H | 3 |
| Dedek, W | 3 |
| Schneider, P | 2 |
| Lohs, K | 1 |
| Gibel, W | 1 |
| Wojcik, J | 1 |
| Fischer, GW | 2 |
| Drudge, JH | 1 |
| Lyons, ET | 1 |
| Taylor, EL | 1 |
| Martson, LV | 1 |
| Voronina, VM | 1 |
| Bello, TR | 2 |
| Berge, GN | 4 |
| Søli, NE | 1 |
| Søgnen, E | 1 |
| Brodal, P | 1 |
| Bauer, C | 1 |
| Bürger, HJ | 1 |
| Nehéz, M | 1 |
| Huszta, E | 1 |
| Mazzag, E | 1 |
| Nafstad, I | 2 |
| Courtney, KD | 1 |
| Andrews, JE | 1 |
| Springer, J | 1 |
| Staszyc, J | 1 |
| Kifer, E | 1 |
| Leĭbovich, DL | 1 |
| Amborski, GF | 1 |
| Torbert, BJ | 1 |
| Dmochowska-Mroczek, H | 1 |
| Lebensztejn, W | 1 |
| Tolwiński, K | 1 |
2 reviews available for trichlorfon and Pregnancy
| Article | Year |
|---|---|
The electrocardiogram of fetal and newborn rats and dysrhythmias induced by toxic exposure.
Topics: Animals; Animals, Newborn; Arrhythmias, Cardiac; Aspirin; Dose-Response Relationship, Drug; Electroc | 1983 |
Cerebellum as a target for toxic substances.
Topics: Animals; Apoptosis; Cerebellum; Cholinesterase Inhibitors; DNA Repair; Embryonic and Fetal Developme | 2000 |
2 trials available for trichlorfon and Pregnancy
| Article | Year |
|---|---|
Controlled test evaluation of the benzimidazole anthelmintic VET 220-S alone or with concomitant trichlorfon treatment against naturally acquired gastrointestinal parasites in ponies.
Topics: Animals; Anthelmintics; Benzimidazoles; Drug Therapy, Combination; Feces; Female; Horse Diseases; Ho | 1991 |
Efficacy of an oxibendazole-trichlorfon paste formulation against third stage larvae of Gasterophilus intestinalis and its safety in horses.
Topics: Administration, Oral; Animals; Benzimidazoles; Clinical Trials as Topic; Diptera; Drug Combinations; | 1986 |
35 other studies available for trichlorfon and Pregnancy
| Article | Year |
|---|---|
Trichlorfon inhibits proliferation and promotes apoptosis of porcine trophectoderm and uterine luminal epithelial cells.
Topics: Animals; Apoptosis; Cell Line; Cell Proliferation; Embryo Implantation; Epithelial Cells; Female; In | 2018 |
The effects of trichlorfon on maternal reproduction and mouse embryo development during organogenesis.
Topics: Animals; Embryonic Development; Environmental Exposure; Female; Insecticides; Male; Mice; Organogene | 2009 |
Effects of repeated maternal oral exposure to low levels of trichlorfon on development and cytogenetic toxicity in 3-day mouse embryos.
Topics: Animals; Blastocyst; Cell Growth Processes; Cytogenetics; Embryonic Development; Female; Insecticide | 2011 |
The effect of trichlorfon and methylazoxymethanol on the development of guinea pig cerebellum.
Topics: Acetylcholinesterase; Acetyltransferases; Animals; Animals, Newborn; Carboxy-Lyases; Cerebellum; Fem | 2007 |
Metrifonate in pregnancy.
Topics: Abnormalities, Drug-Induced; Female; Humans; Pregnancy; Pregnancy Complications, Infectious; Schisto | 1984 |
[Congenital tremor and cerebellar hypoplasia in piglets following treatment of sows with Neguvon during pregnancy].
Topics: Abnormalities, Drug-Induced; Animals; Cerebellum; Female; Pregnancy; Swine; Swine Diseases; Tremor; | 1981 |
[Metrifonate-induced congenital tremor in piglets].
Topics: Animals; Cerebellum; Female; Pregnancy; Prenatal Exposure Delayed Effects; Swine; Swine Diseases; Tr | 1981 |
Metrifonate and dichlorvos: cytogenetic investigations.
Topics: Animals; Bone Marrow Cells; Chromosomes; Dichlorvos; Female; Male; Mice; Mutagenicity Tests; Mutagen | 1981 |
Environmental trichlorfon and cluster of congenital abnormalities.
Topics: Abnormalities, Drug-Induced; Adult; Animals; Case-Control Studies; Cluster Analysis; Diseases in Twi | 1993 |
Human germinal mutagenic effects in relation to intentional and accidental exposure to toxic agents.
Topics: Abnormalities, Drug-Induced; Case-Control Studies; Cluster Analysis; Down Syndrome; Female; Fetal De | 1996 |
Using the Hungarian Birth Defects Registry for surveillance, research and intervention.
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Anthelmintics; Case-Control Studies; Congenital Abno | 1997 |
Praziquantel--its use, cost and possible development of resistance.
Topics: Africa; Animals; Anthelmintics; Child; Drug Resistance; Female; Humans; Oxamniquine; Praziquantel; P | 1999 |
Analysis of cytogenetic and developmental effects on pre-implantation, mid-gestation and near-term mouse embryos after treatment with trichlorfon during zygote stage.
Topics: Abnormalities, Drug-Induced; Aneuploidy; Animals; Cell Survival; Embryo, Mammalian; Embryonic Develo | 2000 |
Clinical evaluation of febantel and trichlorfon paste formulations in the horse.
Topics: Acetanilides; Animals; Ascariasis; Drug Therapy, Combination; Female; Guanidines; Horse Diseases; Ho | 1978 |
Dipterex teratogenicity in the rat, hamster, and mouse when given by gavage.
Topics: Animals; Cholinesterase Inhibitors; Cricetinae; Dose-Response Relationship, Drug; Female; Fetus; Ges | 1979 |
[Testing of the teratogenic activity of chlorophos on the golden hamster and white mice].
Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Female; Fetus; Male; Mesocricetus; Mice; Pregnancy | 1979 |
Congenital ataxia and tremor with cerebellar hypoplasia in piglets borne by sows treated with Neguvon vet. (metrifonate, trichlorfon) during pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Ataxia; Cerebellum; Cholinesterases; Erythro | 1978 |
[Experimental assays on the effect of subtoxic doses of dipterex and metasistox on pregnant animals, embryos and the fate of fetuses].
Topics: Animals; Chick Embryo; Embryo, Mammalian; Female; Fetus; Insecticides; Maternal-Fetal Exchange; Orga | 1975 |
Trichlorfon toxicity in pigs.
Topics: Animals; Animals, Newborn; Cholinesterases; Disease Outbreaks; Female; Male; Pregnancy; Swine; Swine | 1977 |
[The effect of large doses of demethyltrichlorfon and ethyltrichlorfon on the embryonic development of laboratory mice].
Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Female; Fetal Death; Fetus; | 1976 |
Studies on the alkylating properties of trichlorphone and dimethoate in mammals.
Topics: Alkylation; Animals; Carcinogens; Dimethoate; Female; Guanine; Male; Mice; Pregnancy; Rats; Time Fac | 1975 |
[Effect of foschlor in drinking water on organs of 3 generations of rats].
Topics: Adrenal Glands; Animals; Drinking; Female; Liver; Pregnancy; Rats; Reproduction; Trichlorfon; Water | 1975 |
[The mutagenicity of desmethyltrichlorphone in dominant lethal test on mice (author's transl)].
Topics: Animals; Embryo Implantation; Female; Fetal Death; Fetus; Genes, Dominant; Genes, Lethal; Male; Mice | 1975 |
Critical tests and safety studies on trichlorfon as an antiparasitic agent in the horse.
Topics: Administration, Oral; Animals; Diptera; Female; Horses; Injections, Intramuscular; Male; Nematode In | 1976 |
Experimental study of the effect of a series of phosphoroorganic pesticides (Dipterex and Imidan) on embryogenesis.
Topics: Animals; Embryo, Mammalian; Female; Insecticides; Lethal Dose 50; Phosmet; Pregnancy; Rats; Teratoge | 1976 |
Neurotoxicological examination of the piglet brain after prenatal and postnatal exposure to trichlorfon.
Topics: Animals; Brain; Embryonic and Fetal Development; Female; Male; Organ Size; Pregnancy; Prenatal Expos | 1987 |
Neurotoxic effects of prenatal trichlorfon administration in pigs.
Topics: Animals; Brain; Embryonic and Fetal Development; Female; Male; Organ Size; Pregnancy; Prenatal Expos | 1987 |
Cytogenetic, genetic, and embryotoxicity studies with dimethyl 2,2,2-trichloro-1-(2,2,2-trichloro-1-hydroxyethoxy)-ethylphosphonat e, a hypothetical impurity in technical grade trichlorfon.
Topics: Animals; Bone Marrow; Chromosome Aberrations; Embryo, Mammalian; Female; Insecticides; Mice; Mice, I | 1987 |
Distribution and placental transfer of trichlorfon in guinea pigs.
Topics: Animals; Autoradiography; Female; Guinea Pigs; Liver; Placenta; Pregnancy; Time Factors; Tissue Dist | 1986 |
Prenatal effects of trichlorfon on the guinea pig brain.
Topics: Animals; Brain Diseases; Cerebellum; Cerebral Cortex; Choline O-Acetyltransferase; Female; Glutamate | 1986 |
Assessment of teratogenic potential of trichlorfon in mice and rats.
Topics: Animals; Body Weight; Female; Fetus; Mice; Pregnancy; Rats; Species Specificity; Teratogens; Trichlo | 1986 |
[Studies on the effect of the phosphororganic preparation on organism of pregnant rats, foetuses and the cells in tissue culture (author's transl)].
Topics: Animals; Female; Fetus; Maternal-Fetal Exchange; Pregnancy; Rats; Skin; Trichlorfon | 1974 |
[Evaluation of the embryotropic action of small doses of the organophosphate toxic chemicals, chlorophos, metaphos and carbophos].
Topics: Administration, Oral; Animals; Body Height; Body Weight; Dose-Response Relationship, Drug; Embryo, M | 1973 |
Effects of organic phosphorus anthelmintics on blood cholinesterase values in horses and ponies.
Topics: Animals; Anthelmintics; Cholinesterases; Dichlorvos; Female; Hemoglobins; Horse Diseases; Horses; In | 1974 |
[Severe intoxication with Dipterex in a pregnant woman].
Topics: Adolescent; Female; Humans; Insecticides; Neurologic Manifestations; Poisoning; Pregnancy; Pregnancy | 1972 |