trichlorfon has been researched along with Cognition Disorders in 14 studies
Trichlorfon: An organochlorophosphate cholinesterase inhibitor that is used as an insecticide for the control of flies and roaches. It is also used in anthelmintic compositions for animals. (From Merck, 11th ed)
trichlorfon : A phosphonic ester that is dimethyl phosphonate in which the hydrogen atom attched to the phosphorous is substituted by a 2,2,2-trichloro-1-hydroxyethyl group.
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Primary efficacy variables were the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) and the Clinician's Interview-Based Impression of Change with Caregiver Input (CIBIC-plus)." | 2.69 | Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease. ( Bieber, F; Cyrus, PA; Gulanski, B; Mas, J; Morris, JC; Orazem, J; Ruzicka, BB, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 8 (57.14) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spowart-Manning, L | 1 |
| van der Staay, FJ | 1 |
| Schneider, LS | 3 |
| Becker, RE | 1 |
| Colliver, JA | 1 |
| Markwell, SJ | 1 |
| Moriearty, PL | 1 |
| Unni, LK | 1 |
| Vicari, S | 1 |
| Cummings, JL | 4 |
| Cyrus, PA | 4 |
| Bieber, F | 2 |
| Mas, J | 2 |
| Orazem, J | 2 |
| Gulanski, B | 2 |
| Morris, JC | 1 |
| Ruzicka, BB | 2 |
| Peskind, ER | 1 |
| Raskind, MA | 1 |
| Gulanski, BI | 1 |
| Ringman, JM | 1 |
| Mega, MS | 1 |
| O'Connor, SM | 1 |
| Dinov, ID | 1 |
| Reback, E | 1 |
| Felix, J | 1 |
| Masterman, DL | 1 |
| Phelps, ME | 1 |
| Small, GW | 1 |
| Toga, AW | 1 |
| Nadel, A | 1 |
| Masterman, D | 1 |
| Akimov, GA | 1 |
| Buchko, VM | 1 |
| Kremleva, RV | 1 |
4 reviews available for trichlorfon and Cognition Disorders
| Article | Year |
|---|---|
New therapeutic approaches to Alzheimer's disease.
Topics: Alzheimer Disease; Antioxidants; Carbamates; Cholinergic Agents; Cholinesterase Inhibitors; Cognitio | 1996 |
Pharmacologic approaches to cognitive deficits in Alzheimer's disease.
Topics: Alzheimer Disease; Antioxidants; Cholinesterase Inhibitors; Clinical Trials as Topic; Cognition Diso | 1998 |
New therapeutic approaches to cognitive impairment.
Topics: Aged; Alzheimer Disease; Antioxidants; Carbamates; Cholinesterase Inhibitors; Cognition Disorders; D | 1998 |
Metrifonate: update on a new antidementia agent.
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Clinical Trials as Topic; Cognition Disorders | 1999 |
6 trials available for trichlorfon and Cognition Disorders
| Article | Year |
|---|---|
Effects of metrifonate on cognitive decline in Alzheimer disease: a double-blind, placebo-controlled, 6-month study.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Double-Blind Method; Female | 1998 |
Metrifonate treatment of the cognitive deficits of Alzheimer's disease. Metrifonate Study Group.
Topics: Aged; Alzheimer Disease; Behavior; Cholinesterase Inhibitors; Cognition Disorders; Dose-Response Rel | 1998 |
Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Behavior; Cholinesterase Inhibitors; Cognition Disorders | 1998 |
The effects of metrifonate on the cognitive, behavioral, and functional performance of Alzheimer's disease patients. Metrifonate Study Group.
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; | 1999 |
Cognitive and metabolic responses to metrifonate therapy in Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cholinesterase Inhibitors; Cognition Disorders; F | 2001 |
Efficacy of metrifonate in improving the psychiatric and behavioral disturbances of patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antipsychotic Agents; Anxiety; Apolipoproteins E; Behavi | 2001 |
4 other studies available for trichlorfon and Cognition Disorders
| Article | Year |
|---|---|
Spatial discrimination deficits by excitotoxic lesions in the Morris water escape task.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cholinesterase Inhibitors; Cognition Disorders; Dis | 2005 |
Metrifonate for Alzheimer's disease patients.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Cognition Disorders; Humans; | 2000 |
Alzheimer's disease: translating neurochemical insights into clinical benefits.
Topics: Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Cognition Disorders; Humans; Magnetic Reso | 2000 |
[Neurological disorders in chlorophos poisoning].
Topics: Cognition Disorders; Humans; Hyperkinesis; Movement Disorders; Neurologic Manifestations; Paralysis; | 1975 |