trichlorfon has been researched along with Abnormalities, Drug-Induced in 13 studies
Trichlorfon: An organochlorophosphate cholinesterase inhibitor that is used as an insecticide for the control of flies and roaches. It is also used in anthelmintic compositions for animals. (From Merck, 11th ed)
trichlorfon : A phosphonic ester that is dimethyl phosphonate in which the hydrogen atom attched to the phosphorous is substituted by a 2,2,2-trichloro-1-hydroxyethyl group.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " (metrifonate, trichlorfon) during pregnancy." | 7.66 | Congenital ataxia and tremor with cerebellar hypoplasia in piglets borne by sows treated with Neguvon vet. (metrifonate, trichlorfon) during pregnancy. ( Askaa, J; Basse, A; Bitsch, V; Eskildsen, M; Knox, B; Mandrup, M; Ottosen, HE; Overby, E; Pedersen, KB; Rasmussen, F, 1978) |
| " (metrifonate, trichlorfon) during pregnancy." | 3.66 | Congenital ataxia and tremor with cerebellar hypoplasia in piglets borne by sows treated with Neguvon vet. (metrifonate, trichlorfon) during pregnancy. ( Askaa, J; Basse, A; Bitsch, V; Eskildsen, M; Knox, B; Mandrup, M; Ottosen, HE; Overby, E; Pedersen, KB; Rasmussen, F, 1978) |
| "Trichlorfon is an organophosphate insecticide widely used in aquaculture and agriculture." | 1.51 | Effects of low doses Trichlorfon exposure on Rana chensinensis tadpoles. ( Ke, Y; Li, B; Ma, Y; Zhang, Y, 2019) |
| "Trichlorfon has been widely used in agriculture as a broad spectrum insecticide." | 1.31 | Analysis of cytogenetic and developmental effects on pre-implantation, mid-gestation and near-term mouse embryos after treatment with trichlorfon during zygote stage. ( Ishikawa, H; Tian, Y; Yamauchi, T, 2000) |
| " In the first case, for example, the Ministry of Health changed the policy of using high oestrogens dosage (which increased the risk of this defect 6." | 1.30 | Using the Hungarian Birth Defects Registry for surveillance, research and intervention. ( Czeizel, AE; Siffel, C, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (38.46) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, Y | 1 |
| Li, B | 1 |
| Ke, Y | 1 |
| Zhang, Y | 1 |
| Monson, MH | 1 |
| Alexander, K | 1 |
| Fatzer, R | 1 |
| Häni, H | 1 |
| Scholl, E | 1 |
| Mehl, A | 1 |
| Schanke, TM | 1 |
| Johnsen, BA | 1 |
| Fonnum, F | 1 |
| Czeizel, AE | 4 |
| Elek, C | 1 |
| Gundy, S | 1 |
| Métneki, J | 1 |
| Nemes, E | 1 |
| Reis, A | 1 |
| Sperling, K | 1 |
| Tímár, L | 1 |
| Tusnády, G | 1 |
| Virágh, Z | 1 |
| Siffel, C | 1 |
| Tian, Y | 1 |
| Ishikawa, H | 1 |
| Yamauchi, T | 1 |
| Martson', LV | 1 |
| Knox, B | 1 |
| Askaa, J | 1 |
| Basse, A | 1 |
| Bitsch, V | 1 |
| Eskildsen, M | 1 |
| Mandrup, M | 1 |
| Ottosen, HE | 1 |
| Overby, E | 1 |
| Pedersen, KB | 1 |
| Rasmussen, F | 1 |
| Scheufler, H | 1 |
| Dedek, W | 1 |
| Schneider, P | 1 |
| Nedopitanskaia, NN | 1 |
| Prisiazhniuk, TN | 1 |
| Petrovskaia, OG | 1 |
1 review available for trichlorfon and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[Late toxic effects of chlorophos (review of the literature)].
Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Disease Models, Animal; Embryo, Mammalian; Mice; M | 1991 |
12 other studies available for trichlorfon and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Effects of low doses Trichlorfon exposure on Rana chensinensis tadpoles.
Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Erythrocytes; Insecticides; | 2019 |
Metrifonate in pregnancy.
Topics: Abnormalities, Drug-Induced; Female; Humans; Pregnancy; Pregnancy Complications, Infectious; Schisto | 1984 |
[Congenital tremor and cerebellar hypoplasia in piglets following treatment of sows with Neguvon during pregnancy].
Topics: Abnormalities, Drug-Induced; Animals; Cerebellum; Female; Pregnancy; Swine; Swine Diseases; Tremor; | 1981 |
The effect of trichlorfon and other organophosphates on prenatal brain development in the guinea pig.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Brain; Cholinesterase Inhibitors; Dichlorvos; Dos | 1994 |
Environmental trichlorfon and cluster of congenital abnormalities.
Topics: Abnormalities, Drug-Induced; Adult; Animals; Case-Control Studies; Cluster Analysis; Diseases in Twi | 1993 |
Pesticides and birth defects.
Topics: Abnormalities, Drug-Induced; Humans; Hungary; Infant, Newborn; Insecticides; Pesticides; Trichlorfon | 1996 |
Human germinal mutagenic effects in relation to intentional and accidental exposure to toxic agents.
Topics: Abnormalities, Drug-Induced; Case-Control Studies; Cluster Analysis; Down Syndrome; Female; Fetal De | 1996 |
Using the Hungarian Birth Defects Registry for surveillance, research and intervention.
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Anthelmintics; Case-Control Studies; Congenital Abno | 1997 |
Analysis of cytogenetic and developmental effects on pre-implantation, mid-gestation and near-term mouse embryos after treatment with trichlorfon during zygote stage.
Topics: Abnormalities, Drug-Induced; Aneuploidy; Animals; Cell Survival; Embryo, Mammalian; Embryonic Develo | 2000 |
[Testing of the teratogenic activity of chlorophos on the golden hamster and white mice].
Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Female; Fetus; Male; Mesocricetus; Mice; Pregnancy | 1979 |
Congenital ataxia and tremor with cerebellar hypoplasia in piglets borne by sows treated with Neguvon vet. (metrifonate, trichlorfon) during pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Ataxia; Cerebellum; Cholinesterases; Erythro | 1978 |
[The effect of large doses of demethyltrichlorfon and ethyltrichlorfon on the embryonic development of laboratory mice].
Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Female; Fetal Death; Fetus; | 1976 |