tricetin has been researched along with Pneumonia* in 1 studies
1 other study(ies) available for tricetin and Pneumonia
| Article | Year |
|---|---|
Inhibition of LPS-induced pulmonary inflammation by specific flavonoids.
In the present study, the anti-inflammatory effects of the flavonoids flavone, fisetin and tricetin were evaluated in a mouse model of LPS-induced acute pulmonary inflammation. The flavonoid fisetin significantly reduced lung myeloperoxidase-levels and gene-expression of inflammatory mediators such as IL-6, TNF-alpha, IL-1beta, MIP-1alpha and MIP-2. The LPS-induced gene transcription of HO-1 and SOD2 was also significantly reduced by fisetin. Overall, the anti-inflammatory effects of fisetin in this in vivo model were much more pronounced as compared to the observed effects of flavone or tricetin and the anti-inflammatory glucocorticoid dexamethasone. The results of this study indicate that flavonoids such as fisetin might be potential candidates as pharmaceuticals or nutraceuticals in the treatment of pulmonary inflammatory diseases. Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromones; Flavones; Flavonoids; Flavonols; Gene Expression; Heme Oxygenase-1; Inflammation Mediators; Interleukin-6; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Peroxidase; Pneumonia; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Superoxide Dismutase | 2009 |