tribulus and Polycystic-Ovary-Syndrome

tribulus has been researched along with Polycystic-Ovary-Syndrome* in 1 studies

Other Studies

1 other study(ies) available for tribulus and Polycystic-Ovary-Syndrome

Article	Year
Anti-Androgenic Activity of Nardostachys jatamansi DC and Tribulus terrestris L. and Their Beneficial Effects on Polycystic Ovary Syndrome-Induced Rat Models. Metabolic syndrome and related disorders, 2015, Volume: 13, Issue:6 Polycystic ovary syndrome (PCOS) is a major hyperandrogenic disorder. Many drugs prescribed specifically to treat PCOS have side effects; however, previous studies suggest that natural therapeutics including botanicals may be less invasive and equally effective for the management of PCOS.. In the present study, plants were screened for antiandrogenic activity using the RIKILT yeast Androgen bioAssay (RAA). Selected positive plants were subsequently tested for their efficacy against PCOS induced by estradiol valerate (EV) in rat models.. RAA revealed the antiandrogenic property of Nardostachys jatamansi DC (NJ), Tribulus terrestris L. (TT), and Embelia tsjeriam-cottam DC (EJ), whereas Whithania somnifera Dunal (WS), Symplocos racemosa Roxb. (SR), and Helicteres isora L. (HI) exhibited androgenic properties. EJ also exhibited mild androgenic activity and therefore was excluded from further study. EV administration reduced the weight gain and disrupted cyclicity in all rats. NJ and TT extract treatment normalized estrous cyclicity and steroidal hormonal levels and regularized ovarian follicular growth.. The in vitro antiandrogenic activity of plant extracts and their positive effects on different parameters of PCOS were proved in vivo. Topics: Androgen Antagonists; Animals; Biomarkers; Disease Models, Animal; Estradiol; Estrous Cycle; Female; Nardostachys; Ovarian Follicle; Phytotherapy; Plant Extracts; Plants, Medicinal; Polycystic Ovary Syndrome; Progesterone; Rats, Sprague-Dawley; Testosterone; Time Factors; Tribulus; Weight Gain	2015

Article

Year

Anti-Androgenic Activity of Nardostachys jatamansi DC and Tribulus terrestris L. and Their Beneficial Effects on Polycystic Ovary Syndrome-Induced Rat Models.

Metabolic syndrome and related disorders, 2015, Volume: 13, Issue:6

Polycystic ovary syndrome (PCOS) is a major hyperandrogenic disorder. Many drugs prescribed specifically to treat PCOS have side effects; however, previous studies suggest that natural therapeutics including botanicals may be less invasive and equally effective for the management of PCOS.. In the present study, plants were screened for antiandrogenic activity using the RIKILT yeast Androgen bioAssay (RAA). Selected positive plants were subsequently tested for their efficacy against PCOS induced by estradiol valerate (EV) in rat models.. RAA revealed the antiandrogenic property of Nardostachys jatamansi DC (NJ), Tribulus terrestris L. (TT), and Embelia tsjeriam-cottam DC (EJ), whereas Whithania somnifera Dunal (WS), Symplocos racemosa Roxb. (SR), and Helicteres isora L. (HI) exhibited androgenic properties. EJ also exhibited mild androgenic activity and therefore was excluded from further study. EV administration reduced the weight gain and disrupted cyclicity in all rats. NJ and TT extract treatment normalized estrous cyclicity and steroidal hormonal levels and regularized ovarian follicular growth.. The in vitro antiandrogenic activity of plant extracts and their positive effects on different parameters of PCOS were proved in vivo.

Topics: Androgen Antagonists; Animals; Biomarkers; Disease Models, Animal; Estradiol; Estrous Cycle; Female; Nardostachys; Ovarian Follicle; Phytotherapy; Plant Extracts; Plants, Medicinal; Polycystic Ovary Syndrome; Progesterone; Rats, Sprague-Dawley; Testosterone; Time Factors; Tribulus; Weight Gain

2015