Page last updated: 2024-08-24

triazoles and Thrombopenia

triazoles has been researched along with Thrombopenia in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19906 (26.09)18.7374
1990's11 (47.83)18.2507
2000's0 (0.00)29.6817
2010's4 (17.39)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Carter, BW; Colen, R; Fu, S; Gong, J; Hong, DS; Janku, F; Karp, DD; McQuinn, L; Meric-Bernstam, F; Milton, DR; Naing, A; Piha-Paul, SA; Shah, J; Stephen, BA; Sulovic, S; Thein, KZ; Tsimberidou, A; Yap, TA1
Chang, H; Chari, A; Choquet, S; Cole, C; Comenzo, RL; Cornell, RF; Costa, LJ; Crochiere, M; Delforge, M; Dimopoulos, M; Dingli, D; Doyen, C; Engelhardt, M; Facon, T; Frenzel, L; Gavriatopoulou, M; Hoffman, JE; Huff, CA; Illmer, T; Jagannath, S; Kaminetzky, D; Karlin, L; Kauffman, MG; Landesman, Y; Levy, M; Li, L; Lonial, S; Meuleman, N; Mohty, M; Moreau, P; Nooka, AK; Parekh, S; Parker, TL; Perrot, A; Picklesimer, C; Podar, K; Raab, MS; Richardson, PG; Richter, J; Saint-Martin, JR; Schiller, G; Schreder, M; Shacham, S; Shah, J; Stewart, AK; Tang, S; Tuchman, S; Vij, R; Vlummens, P; Vogl, DT; Weisel, KC; Yee, AJ1
Chen, WY; Hung, SJ; Lin, SR1
Abonour, R; Bahlis, N; Baz, R; Berdeja, JG; Chai, Y; Chari, A; Chen, C; Choquet, S; Cornell, RF; Dimopoulos, MA; Dingli, D; Gasparetto, C; Gavriatopoulou, M; Hofmeister, CC; Huff, CA; Jagannath, S; Jakubowiak, A; Kauffman, MG; Lentzsch, S; Li, K; Li, L; Lonial, S; Mohty, M; Moreau, P; Nooka, AK; Parker, TL; Reece, D; Richter, J; Shacham, S; Shah, J; Siegel, D; Tuchman, S; Unger, TJ; Vogl, DT; Weisel, KC; White, D; Yee, AJ1
Crochiere, M; Italiano, JE; Kashyap, T; Klebanov, B; Landesman, Y; Liu, ZJ; Machlus, KR; Shacham, E; Sola-Visner, M; Soussou, TS; Unger, TJ; Vijey, P; Wu, SK1
Fujita, T; Haba, R; Nishiuchi, T; Ohnishi, H; Okutani, Y; Yoshida, K1
Clavel, M; Decoster, G; Holdener, EE; Klepp, O; Ludwig, C; Pinedo, HM; Renard, G; Sessa, C; Siegenthaler, P; ten Bokkel Huinink, W1
Bailie, MB; Fink, GD; Pearson, JM; Roth, RA1
Bernat, A; Gigo, V; Herbert, JM; Lale, A; LaPlace, MC; Le Fur, G; Lespy, L; Maffrand, JP; Savi, P; Valette, G1
Fenton, J; Gudewicz, PW; Kaplan, JE; Moon, DG; van der Zee, H1
Ban, C; Hasegawa, M; Ihara, Y; Inamori, K; Itoh, H; Li, XM; Mori, T; Okagaki, A; Sagawa, N1
Giers, G; Janzarik, H; Kempe, ER; Mueller-Eckhardt, C2
Gibson, JP; Kociba, GJ; Yarrington, JT1
Broersma, R; Gibson, JP; Loudy, DE; Sprinkle-Cavallo, J; Yarrington, JT1
Halonen, M; Lohman, I1
Farhat, M; Feuerstein, G; Perera, PY; Rabinovici, R; Vogel, SN; Yue, TL1
Adamus, WS; Lohmann, HF; Meade, CJ1
Lefort, J; Malanchère, E; Pretolani, M; Vargaftig, BB1
Benshahar, D; Capellaere, P; Kerbrat, P; Rouëssé, JG; Thomas, D; van Coninge, CJ; van Oosterom, AT1
Crespeigne, N; Decoster, G; Dodion, P; Gerard, B; Kenis, Y; Lambert, M; Nicaise, C; Rozencweig, M1
Bruntsch, U; Dodion, P; Hansen, HH; Hansen, M; Pinedo, HM; Renard, J; Ten Bokkel Huinink, WW; Van Glabbeke, M1
Bach, F; Cavalli, F; Hansen, HH; Hansen, SW; Kaplan, S1

Trials

4 trial(s) available for triazoles and Thrombopenia

ArticleYear
Selinexor in combination with carboplatin and paclitaxel in patients with advanced solid tumors: Results of a single-center, multi-arm phase Ib study.
    Investigational new drugs, 2022, Volume: 40, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Female; Humans; Hydrazines; Lung Neoplasms; Nausea; Neoplasms; Ovarian Neoplasms; Paclitaxel; Thrombocytopenia; Triazoles; Vomiting

2022
Oral Selinexor-Dexamethasone for Triple-Class Refractory Multiple Myeloma.
    The New England journal of medicine, 2019, 08-22, Volume: 381, Issue:8

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Dexamethasone; Drug Administration Schedule; Drug Resistance, Neoplasm; Exportin 1 Protein; Female; Humans; Hydrazines; Intention to Treat Analysis; Karyopherins; Male; Middle Aged; Multiple Myeloma; Receptors, Cytoplasmic and Nuclear; Survival Analysis; Thrombocytopenia; Triazoles; Young Adult

2019
Selinexor-induced thrombocytopenia results from inhibition of thrombopoietin signaling in early megakaryopoiesis.
    Blood, 2017, 08-31, Volume: 130, Issue:9

    Topics: Animals; Apoptosis; Blood Platelets; Bone Marrow; Cell Count; Cell Differentiation; Dose-Response Relationship, Drug; Fetus; Hydrazines; Liver; Megakaryocytes; Mice, Knockout; Platelet Activation; Signal Transduction; Stem Cells; Thrombocytopenia; Thrombopoiesis; Thrombopoietin; Triazoles

2017
Phase II trial of anaxirone (TGU) in advanced colorectal cancer: an EORTC Early Clinical Trials Group (ECTG) study.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Colorectal Neoplasms; Female; Humans; Leukopenia; Male; Middle Aged; Neoplasm Metastasis; Thrombocytopenia; Treatment Outcome; Triazoles

1994

Other Studies

19 other study(ies) available for triazoles and Thrombopenia

ArticleYear
Successful Treatment of Recurrent Cutaneous Purpureocillium lilacinum (Paecilomyces lilacinus) Infection with Posaconazole and Surgical Debridement.
    Acta dermato-venereologica, 2019, Dec-01, Volume: 99, Issue:13

    Topics: Administration, Cutaneous; Adult; Anemia, Hemolytic, Autoimmune; Antifungal Agents; Combined Modality Therapy; Debridement; Dermatomycoses; Follow-Up Studies; Humans; Immunocompromised Host; Male; Paecilomyces; Recurrence; Risk Assessment; Severity of Illness Index; Thrombocytopenia; Treatment Outcome; Triazoles

2019
Integrated safety profile of selinexor in multiple myeloma: experience from 437 patients enrolled in clinical trials.
    Leukemia, 2020, Volume: 34, Issue:9

    Topics: Aged; Antineoplastic Agents; Appetite; Clinical Trials as Topic; Diarrhea; Fatigue; Female; Humans; Hydrazines; Hyponatremia; Male; Middle Aged; Multiple Myeloma; Nausea; Thrombocytopenia; Triazoles

2020
Effect of iron chelator deferasirox on chronic anemia and thrombocytopenia in a transfusion-dependent patient with myelodysplastic syndrome.
    International journal of hematology, 2010, Volume: 91, Issue:2

    Topics: Aged; Anemia; Benzoates; Chronic Disease; Deferasirox; Female; Humans; Iron Chelating Agents; Iron Overload; Myelodysplastic Syndromes; Radiography; Thrombocytopenia; Transfusion Reaction; Triazoles

2010
Neither platelet activating factor nor leukotrienes are critical mediators of liver injury after lipopolysaccharide administration.
    Toxicology, 1997, Sep-05, Volume: 121, Issue:3

    Topics: Administration, Oral; Alanine Transaminase; Animals; Azepines; Blood Platelets; Chemical and Drug Induced Liver Injury; Female; Fibrinogen; Hydroxyurea; Injections, Intraperitoneal; Injections, Intravenous; Leukotrienes; Lipopolysaccharides; Lipoxygenase Inhibitors; Liver; Liver Diseases; Necrosis; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thrombocytopenia; Triazoles

1997
Biochemical and pharmacological activities of SR 27417, a highly potent, long-acting platelet-activating factor receptor antagonist.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:1

    Topics: Animals; Azepines; Blood Platelets; Bronchoconstriction; Guinea Pigs; Humans; Injections, Intravenous; Leukopenia; Male; Mice; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thrombocytopenia; Triazoles

1991
Thrombin-induced leukopenia and thrombocytopenia are attenuated by PAF antagonist WEB 2086.
    The Journal of laboratory and clinical medicine, 1991, Volume: 117, Issue:4

    Topics: Animals; Azepines; Carbon Dioxide; Cell Adhesion; Leukocyte Count; Leukopenia; Platelet Activating Factor; Sheep; Thrombin; Thrombocytopenia; Thromboxane B2; Triazoles

1991
The involvement of platelet-activating factor in thrombocytopenia and follicular rupture during gonadotropin-induced superovulation in immature rats.
    Endocrinology, 1991, Volume: 129, Issue:6

    Topics: Animals; Azepines; Chorionic Gonadotropin; Female; Gonadotropins, Equine; Indomethacin; Ovulation; Ovulation Induction; Platelet Activating Factor; Platelet Activation; Platelet Count; Rats; Rats, Inbred Strains; Superovulation; Thrombocytopenia; Triazoles; Vena Cava, Inferior

1991
PAF-acether-antagonist WEB 2086 for treatment of chronic idiopathic thrombocytopenia.
    Lancet (London, England), 1990, Jul-21, Volume: 336, Issue:8708

    Topics: Azepines; Chronic Disease; Drug Evaluation; Humans; Platelet Activating Factor; Thrombocytopenia; Triazoles

1990
Thrombocytopenia in rats and dogs administered the antidepressant compound MDL-19,660.
    Toxicology letters, 1991, Volume: 56, Issue:1-2

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Blood Platelets; Bone Marrow; Bone Marrow Cells; Cell Count; Depression; Dogs; Dose-Response Relationship, Drug; Female; Leukocyte Count; Male; Megakaryocytes; Platelet Count; Rats; Rats, Inbred Strains; Thrombocytopenia; Triazoles

1991
Short-term studies of MDL 19,660-induced canine thrombocytopenia.
    Toxicologic pathology, 1990, Volume: 18, Issue:4 Pt 2

    Topics: Animals; Antidepressive Agents; Blood Platelets; Dogs; Female; Platelet Aggregation; Platelet Aggregation Inhibitors; Prednisone; Thrombocytopenia; Triazoles; Vacuoles

1990
Effects of the PAF antagonist WEB 2086 on PAF-induced physiologic alterations and on IgE anaphylaxis in the rabbit.
    The American review of respiratory disease, 1990, Volume: 142, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Bronchial Spasm; Hypotension; Immunoglobulin E; Leukopenia; Lung; Platelet Activating Factor; Rabbits; Thrombocytopenia; Triazoles

1990
Failure of the platelet-activating-factor antagonist WEB 2086 BS for treatment of chronic autoimmune thrombocytopenia.
    Blut, 1990, Volume: 61, Issue:1

    Topics: Adult; Aged; Autoimmune Diseases; Azepines; Chronic Disease; Drug Evaluation; Female; Humans; Male; Middle Aged; Platelet Activating Factor; Prospective Studies; Thrombocytopenia; Triazoles

1990
Protective effect of BN 50739, a new platelet-activating factor antagonist, in endotoxin-treated rabbits.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:3

    Topics: Animals; Azepines; Blood Cell Count; Endotoxins; Leukopenia; Male; Platelet Activating Factor; Rabbits; Thrombocytopenia; Thromboxane B2; Triazoles

1990
Idiopathic thrombocytopenia treated with Paf-acether antagonist WEB 2086.
    Lancet (London, England), 1988, Nov-12, Volume: 2, Issue:8620

    Topics: Administration, Oral; Azepines; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Count; Thrombocytopenia; Triazines; Triazoles

1988
Interference by the novel PAF-acether antagonist WEB 2086 with the bronchopulmonary responses to PAF-acether and to active and passive anaphylactic shock in guinea-pigs.
    European journal of pharmacology, 1987, Aug-21, Volume: 140, Issue:3

    Topics: Anaphylaxis; Animals; Azepines; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indicators and Reagents; Leukopenia; Male; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Radioimmunoassay; Respiratory System; Spectrometry, Fluorescence; Thrombocytopenia; Thromboxane B2; Triazines; Triazoles

1987
Phase II study of 1,2,4-triglycidyl urasol (TGU) in advanced soft tissue sarcoma. A trial of the EORTC Soft Tissue and Bone Sarcoma Cooperative Group.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; Humans; Leukopenia; Male; Middle Aged; Sarcoma; Soft Tissue Neoplasms; Thrombocytopenia; Triazoles

1987
Phase I study of triglycidylurazol given on a 5-day i.v. schedule.
    Cancer treatment reports, 1986, Volume: 70, Issue:5

    Topics: Adult; Aged; Anemia; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Female; Humans; Injections, Intravenous; Leukopenia; Male; Middle Aged; Neoplasms; Thrombocytopenia; Triazoles

1986
Primary resistance of renal adenocarcinoma to 1,2,4-triglycidylurazol (TGU, NSC 332488), a new triexpoxide cytostatic agent--a phase II study of the EORTC early clinical trials group.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; Humans; Kidney Neoplasms; Leukopenia; Male; Middle Aged; Thrombocytopenia; Triazoles

1986
Phase I trial of 1,2,4-triglycidylurazol (TGU, NSC 332488): a new triepoxide cytostatic agent.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:3

    Topics: Adult; Aged; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Leukopenia; Male; Middle Aged; Neoplasms; Phlebitis; Thrombocytopenia; Triazoles

1985