Compounds > triazoles
Page last updated: 2024-08-24

triazoles and Tauopathies

triazoles has been researched along with Tauopathies in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
Allocca, G; Chu, J; Cornthwaite-Duncan, L; Daykin, H; Hoyer, D; Jacobson, LH; Keenan, RJ1
Aiello, G; Kobeissy, F; Kurup, M; Lin, F; Torres, I; Wang, KK; Yadikar, H; Yang, Z; Yost, R1
Alle, T; Ballatore, C; Brancale, A; Brunden, KR; Cornec, AS; James, MJ; Kovalevich, J; Lee, VM; Lucero, B; Monti, L; Nzou, G; Oukoloff, K; Smith, AB; Trojanowski, JQ; Varricchio, C; Yao, Y1
Ballatore, C; Brunden, KR; Cornec, AS; James, MJ; Koivula, P; Lee, VM; Oukoloff, K; Smith, AB; Trojanowski, JQ; Yao, Y; Zhang, B1
Ballatore, C; Brunden, KR; Cornec, AS; Crowe, A; James, M; Kovalevich, J; Lee, VM; Smith, AB; Trojanowski, JQ; Yao, Y1

Other Studies

5 other study(ies) available for triazoles and Tauopathies

ArticleYear
Differential sleep/wake response and sex differences following acute suvorexant, MK-1064 and zolpidem administration in the rTg4510 mouse model of tauopathy.
    British journal of pharmacology, 2022, Volume: 179, Issue:13

    Topics: Animals; Azepines; Disease Models, Animal; Female; Hypnotics and Sedatives; Male; Mice; Mice, Transgenic; Sex Characteristics; Sleep; Sleep Wake Disorders; Tauopathies; Triazoles; Zolpidem

2022
Screening of tau protein kinase inhibitors in a tauopathy-relevant cell-based model of tau hyperphosphorylation and oligomerization.
    PloS one, 2020, Volume: 15, Issue:7

    Topics: Animals; Cell Line; Cyclosporine; Glycogen Synthase Kinase 3; Lithium Chloride; Mice; Models, Biological; Okadaic Acid; Phosphorylation; Protein Kinase Inhibitors; Protein Multimerization; Rats; Tauopathies; Triazoles

2020
Evaluation of the Structure-Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5-
    Journal of medicinal chemistry, 2021, 01-28, Volume: 64, Issue:2

    Topics: Animals; Brain; Cell Line; Cells, Cultured; Computer Simulation; Humans; Mice; Mice, Transgenic; Microtubules; Models, Molecular; Molecular Docking Simulation; Neurodegenerative Diseases; Neurons; Pyrimidines; Rats; Structure-Activity Relationship; Tauopathies; Triazoles

2021
A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model.
    Molecular neurodegeneration, 2018, 11-07, Volume: 13, Issue:1

    Topics: Alzheimer Disease; Animals; Axonal Transport; Axons; Brain; Disease Models, Animal; Humans; Mice; Microtubules; Neurons; Quinazolines; tau Proteins; Tauopathies; Triazoles

2018
Characterization of Brain-Penetrant Pyrimidine-Containing Molecules with Differential Microtubule-Stabilizing Activities Developed as Potential Therapeutic Agents for Alzheimer's Disease and Related Tauopathies.
    The Journal of pharmacology and experimental therapeutics, 2016, Volume: 357, Issue:2

    Topics: Alzheimer Disease; Animals; Biological Availability; Blood-Brain Barrier; Cell Division; Dose-Response Relationship, Drug; Female; Hydrocarbons, Halogenated; Male; Mice; Microtubules; Neurons; Proteasome Endopeptidase Complex; Pyrimidines; tau Proteins; Tauopathies; Triazoles; Tubulin

2016