Page last updated: 2024-08-24

triazoles and Osteosarcoma

triazoles has been researched along with Osteosarcoma in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's3 (16.67)29.6817
2010's10 (55.56)24.3611
2020's4 (22.22)2.80

Authors

AuthorsStudies
Gong, Z; Su, Q; Tian, Z; Xu, B1
Özgür, A1
Depping, R; Dunst, J; Kosyna, FK; Landesman, Y; Mandl, M; von Fallois, M1
Chen, J; Chen, X; Sun, H; Yang, D1
Castro, R; Daffinrud, J; Krauss, S; Munthe, E; Myklebost, O; Stratford, EW; Waaler, J1
Baud'huin, M; Berreur, M; Bradner, JE; Heymann, D; Jacques, C; Lamoureux, F; Lecanda, F; Ory, B; Rédini, F; Rodriguez Calleja, L1
Bradner, JE; Doan, NB; Forscher, C; Koeffler, HP; Lee, DH; Qi, J; Said, JW; Yang, H1
Baker, EK; Burns, CJ; Chalk, AM; Gupte, A; Sharp, PP; Taylor, S; Walia, M; Walkley, CR; Walsh, NC; Zannettino, AC1
Bagatell, R; Bosse, KR; Fisher, BT; Martino, J1
Gupte, A; Hawkins, CJ; Miles, MA; Shekhar, TM; Tascone, B; Taylor, S; Walkley, CR1
Aboukameel, A; Argueta, C; Azmi, AS; Drolen, C; Kashyap, T; Kauffman, M; Klebanov, B; Landesman, Y; Lee, M; Mohammad, RM; Muqbil, I; Senapedis, W; Shacham, S; Unger, TJ1
Jeong, DK; Kumari, S; Mishra, CB; Mongre, RK; Tiwari, M1
Duncan, JS; Kerman, K; Kraatz, HB; Litchfield, DW; Song, H1
Barsoum, J; Bear, MD; Foley, KP; Fossey, SL; London, CA; McCleese, JK; Mihalek, RM; Ying, W1
Corradini, N; Dannaoui, E; Gay-Andrieu, F; Hoinard, D; Lortholary, O; Méchinaud, F; Roux, BG1
Chao, YY; Jan, CR1
Harvey, W; Hopps, RM; Murphy, CT; Wasil, M1

Reviews

1 review(s) available for triazoles and Osteosarcoma

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide

2023

Trials

1 trial(s) available for triazoles and Osteosarcoma

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide

2023

Other Studies

17 other study(ies) available for triazoles and Osteosarcoma

ArticleYear
Design and development of novel 1,2,3-triazole chalcone derivatives as potential anti-osteosarcoma agents
    Acta pharmaceutica (Zagreb, Croatia), 2022, Sep-01, Volume: 72, Issue:3

    Topics: Adolescent; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Child; Drug Screening Assays, Antitumor; Humans; Osteosarcoma; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Structure-Activity Relationship; TOR Serine-Threonine Kinases; Triazoles

2022
Investigation of anticancer activities of STA-9090 (ganetespib) as a second generation HSP90 inhibitor in Saos-2 osteosarcoma cells.
    Journal of chemotherapy (Florence, Italy), 2021, Volume: 33, Issue:8

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; HSP90 Heat-Shock Proteins; Humans; Inhibitory Concentration 50; Osteosarcoma; Triazoles

2021
Selinexor decreases HIF-1α via inhibition of CRM1 in human osteosarcoma and hepatoma cells associated with an increased radiosensitivity.
    Journal of cancer research and clinical oncology, 2021, Volume: 147, Issue:7

    Topics: Apoptosis; Bone Neoplasms; Carcinoma, Hepatocellular; Cell Proliferation; Exportin 1 Protein; Gene Expression Regulation, Neoplastic; Humans; Hydrazines; Hypoxia-Inducible Factor 1, alpha Subunit; Karyopherins; Liver Neoplasms; Osteosarcoma; Radiation Tolerance; Radiation-Sensitizing Agents; Receptors, Cytoplasmic and Nuclear; Triazoles; Tumor Cells, Cultured

2021
SM‑164 enhances the antitumor activity of adriamycin in human U2‑OS cells via downregulation of X‑linked inhibitor of apoptosis protein.
    Molecular medicine reports, 2019, Volume: 19, Issue:6

    Topics: Antibiotics, Antineoplastic; Apoptosis; Bone Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Caspase 3; Cell Line, Tumor; Cell Survival; Down-Regulation; Doxorubicin; Drug Synergism; Humans; Inhibitor of Apoptosis Proteins; Osteosarcoma; Poly(ADP-ribose) Polymerases; RNA Interference; RNA, Small Interfering; Survivin; Triazoles; X-Linked Inhibitor of Apoptosis Protein

2019
The tankyrase-specific inhibitor JW74 affects cell cycle progression and induces apoptosis and differentiation in osteosarcoma cell lines.
    Cancer medicine, 2014, Volume: 3, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Axin Signaling Complex; Bone Neoplasms; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Humans; Osteogenesis; Osteosarcoma; Oxadiazoles; Tankyrases; Triazoles; Wnt Signaling Pathway

2014
Selective inhibition of BET bromodomain epigenetic signalling interferes with the bone-associated tumour vicious cycle.
    Nature communications, 2014, Mar-19, Volume: 5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Azepines; Blotting, Western; Bone Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred C3H; Mice, Nude; Middle Aged; Nuclear Proteins; Osteosarcoma; Proto-Oncogene Proteins c-myc; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription Factors; Triazoles; Xenograft Model Antitumor Assays; Young Adult

2014
Synergistic effect of JQ1 and rapamycin for treatment of human osteosarcoma.
    International journal of cancer, 2015, May-01, Volume: 136, Issue:9

    Topics: Animals; Apoptosis; Azepines; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Core Binding Factor Alpha 1 Subunit; Cyclin-Dependent Kinase Inhibitor p21; Drug Synergism; Female; G1 Phase Cell Cycle Checkpoints; Genes, myc; Humans; Mice; Mice, Nude; Nuclear Proteins; Osteosarcoma; Sirolimus; Transcription Factors; Transcription Initiation Site; Triazoles; Xenograft Model Antitumor Assays

2015
BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells.
    Scientific reports, 2015, May-06, Volume: 5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Azepines; Cell Cycle Checkpoints; Cell Line, Tumor; Cyclin-Dependent Kinases; Down-Regulation; Drug Synergism; Gene Knockdown Techniques; Humans; Mice; Osteosarcoma; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Transcription Factors; Triazoles

2015
Suspected posaconazole toxicity in a pediatric oncology patient.
    Pediatric blood & cancer, 2015, Volume: 62, Issue:9

    Topics: Adolescent; Anorexia; Antifungal Agents; Combined Modality Therapy; Delayed-Action Preparations; Drug Therapy, Combination; Fatigue; Female; Humans; Hypokalemia; Maxillary Sinus Neoplasms; Medication Errors; Musculoskeletal Pain; Mycoses; Osteosarcoma; Postoperative Complications; Sinusitis; Triazoles

2015
IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα.
    Oncotarget, 2016, Jun-07, Volume: 7, Issue:23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Baculoviral IAP Repeat-Containing 3 Protein; Bone Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Survival; Cyclohexanes; Dose-Response Relationship, Drug; Genetic Predisposition to Disease; HEK293 Cells; Humans; Inhibitor of Apoptosis Proteins; Mice, Knockout; Osteosarcoma; Phenotype; Pyrroles; Receptor-Interacting Protein Serine-Threonine Kinases; Retinoblastoma Protein; Signal Transduction; Thiazoles; TNF-Related Apoptosis-Inducing Ligand; Transfection; Triazoles; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases

2016
Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-κB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death.
    Oncotarget, 2016, Nov-29, Volume: 7, Issue:48

    Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Bortezomib; Cell Death; Cell Line, Tumor; Cell Nucleus; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Exportin 1 Protein; Female; Fibrosarcoma; Humans; Hydrazines; Karyopherins; Mice, Inbred ICR; Mice, SCID; NF-kappa B; NF-KappaB Inhibitor alpha; Osteosarcoma; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Receptors, Cytoplasmic and Nuclear; RNA Interference; Signal Transduction; Time Factors; Transcription Factor RelA; Transfection; Triazoles

2016
Novel Triazole-Piperazine Hybrid Molecules Induce Apoptosis via Activation of the Mitochondrial Pathway and Exhibit Antitumor Efficacy in Osteosarcoma Xenograft Nude Mice Model.
    ACS chemical biology, 2017, 03-17, Volume: 12, Issue:3

    Topics: Animals; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Mice; Mice, Nude; Mitochondria; Neoplasm Metastasis; Osteosarcoma; Piperazines; Triazoles; Xenograft Model Antitumor Assays

2017
Peptide biosensors for the electrochemical measurement of protein kinase activity.
    Analytical chemistry, 2008, Dec-15, Volume: 80, Issue:24

    Topics: Adenosine Triphosphate; Benzimidazoles; Biosensing Techniques; Bone Neoplasms; Casein Kinase II; Catalysis; Electrochemistry; Ferrous Compounds; fms-Like Tyrosine Kinase 3; Humans; Kinetics; Metallocenes; Mutation; Osteosarcoma; Oxidation-Reduction; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Receptor, ErbB-2; Staurosporine; Triazoles; Tumor Cells, Cultured

2008
The novel HSP90 inhibitor STA-1474 exhibits biologic activity against osteosarcoma cell lines.
    International journal of cancer, 2009, Dec-15, Volume: 125, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Bone Neoplasms; Caspase 3; Cell Cycle; Cell Proliferation; Dogs; Female; HSP90 Heat-Shock Proteins; Humans; Immunoprecipitation; Indoles; Mice; Mice, SCID; Osteoblasts; Osteosarcoma; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-kit; STAT3 Transcription Factor; Triazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2009
Successful triple combination therapy of disseminated absidia corymbifera infection in an adolescent with osteosarcoma.
    Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:2

    Topics: Absidia; Adolescent; Amphotericin B; Antineoplastic Agents; Caspofungin; Drug Therapy, Combination; Echinocandins; Female; Femoral Neoplasms; Humans; Lipopeptides; Mucormycosis; Opportunistic Infections; Osteosarcoma; Triazoles

2010
Novel effect of Y-24180, a presumed specific platelet-activating factor receptor antagonist, on Ca2+ levels and growth of human osteosarcoma cells.
    Pharmacological research, 2005, Volume: 51, Issue:3

    Topics: Azepines; Calcium; Calcium Signaling; Cell Death; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Growth Inhibitors; Humans; Osteosarcoma; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Triazoles

2005
Biosynthesis of platelet activating factor (PAF) by an osteosarcoma cell line (UMR 106).
    Biochemical Society transactions, 1991, Volume: 19, Issue:2

    Topics: Animals; Azepines; Cell Line; Enzyme Activation; Kinetics; Osteosarcoma; Phospholipases A; Platelet Activating Factor; Platelet Aggregation; Rats; Sarcoma, Experimental; Triazoles

1991