Compounds > triazoles
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triazoles and Muscle Contraction

triazoles has been researched along with Muscle Contraction in 62 studies

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199011 (17.74)18.7374
1990's24 (38.71)18.2507
2000's16 (25.81)29.6817
2010's11 (17.74)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chi, P; Hong, Z; Shi, H; Sun, Y1
Ciotkowska, A; Gratzke, C; Hennenberg, M; Herlemann, A; Keller, P; Rutz, B; Schott, M; Stief, CG; Strittmatter, F; Tamalunas, A; Waidelich, R; Wang, Y; Yu, Q1
Ventura, S1
Bourmoum, M; Charles, R; Claing, A1
Gratzke, C; Hennenberg, M; Herlemann, A; Rutz, B; Stief, CG; Strittmatter, F; Wang, Y; Yu, Q1
Abd El-Aleam, RH; Abdel-Rahman, HM; El-Daly, ME; George, RF; Hassan, GS; Kamel, AA; Keeton, AB; Lee, KJ; Piazza, GA1
Cho, KH; Choi, S; Im, W; Lee, MJ; Park, HM; Sung, HJ1
Gallego, D; Jimenez, M; Mañé, N; Martin, MT; Martinez-Cutillas, M1
Brozmanova, M; Hu, Y; Kollarik, M; Mazurova, L; Ru, F; Tatar, M; Yu, S1
Aloisi, AM; Ceccarelli, I; Fiorenzani, P; Pessina, F; Sgaragli, G; Valeri, A1
Jiang, MJ; Tsai, MH1
Alves-Do-Prado, W; Bornia, EC; Correia-de-Sá, P1
Diniz, C; Gonçalves, J; Leal, S1
Filippi, S; Forti, G; Gelmini, S; Granchi, S; Ledda, F; Luconi, M; Maggi, M; Mancina, R; Marini, M; Morelli, A; Orlando, C; Vannelli, GB; Vignozzi, L1
Alkorta, I; Alsasua, A; Dannert, MT; Goya, P; Hernandez-Folgado, L; Jagerovic, N; Martín, MI; Navarro, M; Pascual, D; Rodriguez de Fonseca, F; Serrano, A; Suardiaz, M1
Jähnichen, S; Pertz, HH; Radtke, OA1
Crescioli, C; Ferruzzi, P; Filippi, S; Forti, G; Ledda, F; Maggi, M; Mancina, R; Marini, M; Mondaini, N; Morelli, A; Vannelli, GB; Vignozzi, L1
Elmedal, B; Mulvany, MJ; Simonsen, U1
Antonioli, L; Blandizzi, C; Colucci, R; Del Tacca, M; Fornai, M; Ghisu, N1
Mulè, F; Serio, R; Zizzo, MG1
Boido, A; Boido, CC; Budriesi, R; Chiarini, A; Ioan, P; Sparatore, F; Terranova, E1
Carneiro, FS; Giachini, FR; Inscho, EW; Leite, R; Tostes, RC; Webb, RC1
Chichester, P; Juan, YS; Levin, RM; Lin, WY; Mannikarottu, A; Rehfuss, A; Whitbeck, C1
Wang, Q; Wang, W; Wang, Y; Wu, J; Wu, X; Xu, J1
Andersson, RG; Grundström, N; Hedman, S; Sörenby, L; Wikberg, JE1
Clarke, GD; Harling, EJ; Hassall, PA; Ross, JW; Smith, H; Spicer, BA; Taylor, JF1
Merican, Z; Nott, MW1
Hay, DW; Hubbard, WC; Undem, BJ1
Nevala, R; Paakkari, I; Peitola, A; Vapaatalo, H1
Jarvis, JE; Reeves, JJ; Sheehan, MJ; Strong, P1
Alabaster, VA; Cheeseman, HE; Cooper, K; deSouza, RN; Keir, RF; Parry, MJ1
Dahlén, SE; Jonsson, EW1
Brown, MJ; Ferro, A; Hill, RG; Longmore, J1
Coceani, F; Kelsey, L; Korzekwa, K; Seidlitz, E1
Boulanger, CM; Desta, B; Hill, RG; Longmore, J; Schofield, WN; Taylor, AA1
Poucher, SM1
Andersson, RG; Grenegård, M; Johansson Rydberg, IG1
Van de Voorde, J; Vanheel, B1
Hayakawa, T; Kamei, C; Kishida, H; Mihara, T; Nakayama, Y; Sugimoto, Y1
Eltze, M1
Fujimori, A; Inagaki, O; Kikuchi, K; Kurihara, H; Okazaki, T; Shibasaki, M; Suga, A; Watanabe, T; Yanagisawa, I1
Biagi, G; Calderone, V; Giorgi, I; Livi, O; Martinotti, E; Scartoni, V1
Bertaccini, G; Coppelli, G; Coruzzi, G; Poli, E; Pozzoli, C1
Alloatti, G; Camussi, G; Mariano, F; Penna, C1
Konieczny, J; Lorenc-Koci, E; Wardas, J1
Hamann, M; Richter, A1
Anderson, WH; Fitzpatrick, DF; Hwang, DP; Krzanowski, JJ; Polson, JB; Szentivanyi, A1
Ghirardi, O; Maccari, F; Pacifici, L; Ramacci, MT; Sale, P1
Gavrovskaya, LK; Goldfarb, VL; Grechishkin, LL1
Kishimoto, K; Matsuzaki, M; Nakajima, A; Okazaki, I; Onodera, K1
Aibara, S; Fujiwara, H; Iwamoto, T; Matsumoto, H; Miwa, T; Mori, M; Moroi, R; Nakayama, K; Tsukada, W; Yokohama, S1
Kane, JM; Kehne, JH; Ketteler, HJ; McCloskey, TC; Palfreyman, MG; Senyah, Y1
Damasiewicz, B; Foks, H; Głowka, M; Kaliszan, R; Nasal, A; Okopień, B; Petrusewicz, J; Radwańska, A; Rudnicka, W; Trzeciak, H1
Peskar, BA; Pritze, S; Simmet, T1
Czarnocka-Janowicz, A; Damasiewicz, B; Foks, H; Kaliszan, R; Nasal, A; Petrusewicz, J; Radwańska, A1
Aliau, S; Descomps, B; Tabacik, C; Valentin, JP1
Gerring, EL; King, JN1
Armour, CL; Black, JL; Johnson, PR1
Camerino, DC; Lograno, MD; Reibaldi, A1
Del Monte, M; Subissi, A1
Fermum, R; Meisel, P1
Barth, A; Förster, W; Mentz, P1

Other Studies

62 other study(ies) available for triazoles and Muscle Contraction

ArticleYear
Inhibition of JAK1 mitigates postoperative ileus in mice.
    Surgery, 2019, Volume: 166, Issue:6

    Topics: Animals; Disease Models, Animal; Gastrointestinal Motility; Humans; Ileus; Inflammation Mediators; Intestinal Mucosa; Janus Kinase 1; Jejunum; Male; Mice; Muscle Contraction; Muscle, Smooth; Peroxidase; Postoperative Complications; Preoperative Care; Pyridines; Signal Transduction; Triazoles; Up-Regulation

2019
Inhibition of smooth muscle contraction and ARF6 activity by the inhibitor for cytohesin GEFs, secinH3, in the human prostate.
    American journal of physiology. Renal physiology, 2018, 01-01, Volume: 314, Issue:1

    Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Humans; Male; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Prostate; Prostatic Neoplasms; Triazoles

2018
Toward better treatment for lower urinary tract symptoms associated with benign prostatic hyperplasia?
    American journal of physiology. Renal physiology, 2018, 07-01, Volume: 315, Issue:1

    Topics: Humans; Lower Urinary Tract Symptoms; Male; Muscle Contraction; Prostatic Hyperplasia; Triazoles

2018
ARF GTPases control phenotypic switching of vascular smooth muscle cells through the regulation of actin function and actin dependent gene expression.
    Cellular signalling, 2018, Volume: 46

    Topics: Actin Cytoskeleton; Actins; ADP-Ribosylation Factor 1; ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Animals; Cell Adhesion; Cell Differentiation; Gene Expression Regulation; Microfilament Proteins; Muscle Contraction; Muscle Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Rats; Signal Transduction; Stress Fibers; Transcription Factors; Triazoles

2018
Inhibition of prostatic smooth muscle contraction by the inhibitor of G protein-coupled receptor kinase 2/3, CMPD101.
    European journal of pharmacology, 2018, Jul-15, Volume: 831

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Aged; Aged, 80 and over; Benzamides; Dose-Response Relationship, Drug; Electric Stimulation; G-Protein-Coupled Receptor Kinase 2; G-Protein-Coupled Receptor Kinase 3; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Phosphorylation; Potassium Chloride; Prostate; Protein Kinase Inhibitors; Pyridines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Signal Transduction; Triazoles

2018
Design and synthesis of 1,2,4-triazolo[1,5-a]pyrimidine derivatives as PDE 4B inhibitors endowed with bronchodilator activity.
    Archiv der Pharmazie, 2019, Volume: 352, Issue:8

    Topics: Animals; Bronchodilator Agents; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Drug Design; Humans; Male; Molecular Docking Simulation; Molecular Structure; Muscle Contraction; Muscle, Smooth; Phosphodiesterase 4 Inhibitors; Pyrimidines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Trachea; Triazoles

2019
Pharmacological profile of DA-6886, a novel 5-HT4 receptor agonist to accelerate colonic motor activity in mice.
    European journal of pharmacology, 2014, Jul-15, Volume: 735

    Topics: Animals; Benzamides; Carbachol; Colon; Esophagus; Gastrointestinal Motility; Loperamide; Male; Mice, Inbred ICR; Muscle Contraction; Rats; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Triazoles

2014
EP2 and EP4 receptors mediate PGE2 induced relaxation in murine colonic circular muscle: pharmacological characterization.
    Pharmacological research, 2014, Volume: 90

    Topics: Alprostadil; Animals; Azetidines; Colon; Dinoprostone; Female; In Vitro Techniques; Male; Mice, Knockout; Muscle Contraction; Muscle, Smooth; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Thiophenes; Triazoles

2014
Mechanisms of the adenosine A2A receptor-induced sensitization of esophageal C fibers.
    American journal of physiology. Gastrointestinal and liver physiology, 2016, Feb-01, Volume: 310, Issue:3

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Dose-Response Relationship, Drug; Esophagus; Guinea Pigs; In Vitro Techniques; Isoquinolines; Muscle Contraction; Nerve Endings; Nerve Fibers, Unmyelinated; Neuroprotective Agents; Nodose Ganglion; Patch-Clamp Techniques; Phenethylamines; Protein Kinase Inhibitors; Purinergic P2X Receptor Agonists; Pyrimidines; Receptor, Adenosine A2A; Sulfonamides; Transient Receptor Potential Channels; Triazoles; Vagus Nerve

2016
Effects of 17beta-estradiol on rat urinary bladder: gender differences in anoxia-glucopenia and reperfusion damage.
    Neurourology and urodynamics, 2009, Volume: 28, Issue:6

    Topics: Anastrozole; Animals; Aromatase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Glucose; Hypoxia; In Vitro Techniques; Injections, Subcutaneous; Male; Muscle Contraction; Neuroprotective Agents; Nitriles; Rats; Rats, Wistar; Reperfusion Injury; Sex Factors; Testosterone; Time Factors; Triazoles; Urinary Bladder; Urinary Bladder Diseases

2009
Reactive oxygen species are involved in regulating alpha1-adrenoceptor-activated vascular smooth muscle contraction.
    Journal of biomedical science, 2010, Aug-23, Volume: 17

    Topics: Acetophenones; Acetylcysteine; Adrenergic alpha-1 Receptor Agonists; Analysis of Variance; Animals; Benzoxazoles; Blotting, Western; Dose-Response Relationship, Drug; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Phosphatase; Myosins; NADPH Oxidases; Phenylephrine; Phosphorylation; Rats; Reactive Oxygen Species; Receptors, Adrenergic, alpha-1; rhoA GTP-Binding Protein; Triazoles; Vasoconstrictor Agents

2010
Presynaptic facilitatory adenosine A2A receptors mediate fade induced by neuromuscular relaxants that exhibit anticholinesterase activity.
    Clinical and experimental pharmacology & physiology, 2011, Volume: 38, Issue:3

    Topics: Acetylcholine; Animals; Atracurium; Cholinesterase Inhibitors; Diaphragm; Electric Stimulation; Hexamethonium; Male; Muscle Contraction; Neuromuscular Agents; Neuromuscular Junction; Pancuronium; Phrenic Nerve; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Muscarinic M2; Receptors, Nicotinic; Receptors, Presynaptic; Synaptic Transmission; Triazines; Triazoles; Tubocurarine; Vecuronium Bromide

2011
Regional differences in the adenosine A(2) receptor-mediated modulation of contractions in rat vas deferens.
    European journal of pharmacology, 2003, Jan-24, Volume: 460, Issue:2-3

    Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Epididymis; Immunohistochemistry; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phenethylamines; Prostate; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theobromine; Triazines; Triazoles; Vas Deferens; Xanthines

2003
Oxytocin receptor is expressed in the penis and mediates an estrogen-dependent smooth muscle contractility.
    Endocrinology, 2004, Volume: 145, Issue:4

    Topics: Animals; Aromatase Inhibitors; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Gonadotropin-Releasing Hormone; Humans; Hypogonadism; In Vitro Techniques; Letrozole; Male; Muscle Contraction; Muscle, Smooth; Nitriles; Osmolar Concentration; Oxytocin; Penis; Rabbits; Receptors, Oxytocin; Tamoxifen; Triazoles; Triptorelin Pamoate

2004
Discovery of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1h-1,2,4-triazole, a novel in vivo cannabinoid antagonist containing a 1,2,4-triazole motif.
    Journal of medicinal chemistry, 2004, May-20, Volume: 47, Issue:11

    Topics: Animals; Behavior, Animal; Binding, Competitive; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cerebellum; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Triazoles; Vas Deferens

2004
Involvement of 5-HT1B receptors in triptan-induced contractile responses in guinea-pig isolated iliac artery.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:1

    Topics: Animals; Benzamides; Brain; Carbazoles; Dinoprost; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endothelium, Vascular; Female; Forecasting; Guinea Pigs; Iliac Artery; Indoles; Ketanserin; Male; Muscle Contraction; Muscle, Smooth; Oxadiazoles; Oxazolidinones; Piperazines; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Sumatriptan; Triazoles; Tryptamines

2004
Oxytocin mediates the estrogen-dependent contractile activity of endothelin-1 in human and rabbit epididymis.
    Endocrinology, 2005, Volume: 146, Issue:8

    Topics: Animals; Endothelin-1; Epididymis; Estradiol; Hypogonadism; Letrozole; Male; Muscle Contraction; Nitriles; Oxytocin; Rabbits; Rats; Triazoles; Triptorelin Pamoate

2005
Dual impact of a nitric oxide donor, GEA 3175, in human pulmonary smooth muscle.
    European journal of pharmacology, 2005, May-23, Volume: 516, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Albuterol; Bronchi; Bronchodilator Agents; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Peptides; Pulmonary Artery; Quinoxalines; Triazoles; Vasoconstrictor Agents; Vasodilation

2005
A2a receptors mediate inhibitory effects of adenosine on colonic motility in the presence of experimental colitis.
    Inflammatory bowel diseases, 2006, Volume: 12, Issue:2

    Topics: Adenosine; Animals; Colitis; Disease Models, Animal; Gastrointestinal Motility; Intestinal Mucosa; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Tissue Culture Techniques; Triazines; Triazoles

2006
Inhibitory responses to exogenous adenosine in murine proximal and distal colon.
    British journal of pharmacology, 2006, Volume: 148, Issue:7

    Topics: Adenosine; Animals; Colon; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Signal Transduction; Theobromine; Triazoles; Xanthines

2006
Alpha1- and alpha2-adrenoreceptor antagonist profiles of 1- and 2-[omega-(4-arylpiperazin-1-yl)alkyl]-1,2,3-benzotriazoles.
    Chemistry & biodiversity, 2005, Volume: 2, Issue:10

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Male; Molecular Structure; Muscle Contraction; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Triazoles; Vas Deferens

2005
Determination of adenosine effects and adenosine receptors in murine corpus cavernosum.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:2

    Topics: 2-Chloroadenosine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Atropine; Bretylium Tosylate; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Penile Erection; Phenylephrine; Prazosin; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Triazoles

2007
Effect of letrozole on urinary bladder function in the female rabbit.
    BJU international, 2007, Volume: 100, Issue:6

    Topics: Animals; Aromatase Inhibitors; Estrogens; Female; Letrozole; Muscle Contraction; Muscle, Smooth; Nitriles; Rabbits; Testosterone; Triazoles; Urinary Bladder

2007
[Ca2+]i and PKC-alpha are involved in the inhibitory effects of Ib, a novel nonpeptide AngiotensinII subtype AT1 receptor antagonist, on AngiotensinII-induced vascular contraction in vitro.
    Biochemical and biophysical research communications, 2007, Dec-07, Volume: 364, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Calcium; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Protein Kinase C-alpha; Rabbits; Receptor, Angiotensin, Type 1; Tetrazoles; Triazoles

2007
Effects of triazoles on smooth muscle tone and immunologically released bronchoconstrictive mediators in vitro and in vivo.
    Acta pharmacologica et toxicologica, 1984, Volume: 55, Issue:5

    Topics: Airway Resistance; Animals; Bronchi; Guinea Pigs; Histamine Release; Humans; Ileum; In Vitro Techniques; Leukocytes; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Respiratory Hypersensitivity; Triazoles

1984
BRL 22321, a compound that has mast cell stabilizing activity similar to that of disodium cromoglycate and in addition has smooth muscle relaxing activity.
    Agents and actions, 1983, Volume: 13, Issue:4

    Topics: Animals; Cromolyn Sodium; Guinea Pigs; Histamine Release; Immunoglobulin E; Lung; Male; Mast Cells; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Passive Cutaneous Anaphylaxis; Rats; Rats, Inbred Strains; Triazoles

1983
Effects of isoprenaline, levodopa and a phosphodiesterase inhibitor (ICI 63,197) on cyclic AMP levels and contractions of soleus muscles in anesthetized cats.
    Clinical and experimental pharmacology & physiology, 1981, Volume: 8, Issue:1

    Topics: Anesthesia; Animals; Cats; Cyclic AMP; Female; Isoproterenol; Levodopa; Male; Muscle Contraction; Muscles; Phosphodiesterase Inhibitors; Pyrimidines; Triazoles

1981
Endothelin-induced contraction and mediator release in human bronchus.
    British journal of pharmacology, 1993, Volume: 110, Issue:1

    Topics: Acetylcholine; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Bronchi; Dicarboxylic Acids; Endothelins; Fatty Acids, Unsaturated; Histamine Release; Humans; Hydrazines; In Vitro Techniques; Indomethacin; Inflammation; Leukotrienes; Lung; Meclofenamic Acid; Muscle Contraction; Muscle, Smooth; Platelet Aggregation Inhibitors; Prostaglandins; Spectrometry, Fluorescence; SRS-A; Thromboxane A2; Triazoles

1993
Effect of nitric oxide donors on rat bronchial muscle in vitro.
    Agents and actions. Supplements, 1995, Volume: 45

    Topics: Animals; Bronchi; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitroprusside; Rats; Rats, Wistar; Triazoles

1995
Further investigations into adenosine A1 receptor-mediated contraction in rat colonic muscularis mucosae and its augmentation by certain alkylxanthine antagonists.
    British journal of pharmacology, 1995, Volume: 114, Issue:5

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colon; Cyclooxygenase Inhibitors; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Theophylline; Triazoles; Vasodilator Agents; Xanthines

1995
Pharmacological profile of UK-74,505, a novel and selective PAF antagonist with potent and prolonged oral activity.
    Journal of lipid mediators and cell signalling, 1994, Volume: 10, Issue:3

    Topics: Administration, Oral; Animals; Aorta; Azepines; Blood Platelets; Brain; Calcium Channels, L-Type; Capillary Permeability; Cattle; Dihydropyridines; Diltiazem; Gallopamil; Guinea Pigs; Hypotension; Imidazoles; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle Proteins; Nitrendipine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Potassium Chloride; Rabbits; Rats; Rats, Sprague-Dawley; Skin; Triazoles; Tritium

1994
Interactions between leukotrienes and histamine in the anaphylactic contraction of guinea pig lung parenchyma.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Guinea Pigs; Histamine; In Vitro Techniques; Indoles; Indomethacin; Leukotriene Antagonists; Leukotrienes; Lung; Male; Muscle Contraction; Ovalbumin; Platelet Activating Factor; Quinolines; Triazoles

1994
A comparison of the contractile effects of 5-hydroxytryptamine, sumatriptan and MK-462 on human coronary artery in vitro.
    British journal of clinical pharmacology, 1995, Volume: 40, Issue:3

    Topics: Coronary Vessels; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Serotonin; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Triazoles; Tryptamines; Vasoconstriction

1995
Inhibition of the contraction of the ductus arteriosus to oxygen by 1-aminobenzotriazole, a mechanism-based inactivator of cytochrome P450.
    British journal of pharmacology, 1996, Volume: 117, Issue:7

    Topics: Animals; Cyclic GMP; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ductus Arteriosus; Endothelins; Female; Fetus; Guinea Pigs; In Vitro Techniques; Mixed Function Oxygenases; Muscle Contraction; Muscle, Smooth, Vascular; Oxygen; Pregnancy; Sheep; Triazoles; Vasoconstriction

1996
5-HT1D receptor agonists and human coronary artery reactivity in vitro: crossover comparisons of 5-HT and sumatriptan with rizatriptan and L-741,519.
    British journal of clinical pharmacology, 1996, Volume: 42, Issue:4

    Topics: Adult; Aged; Arteries; Coronary Vessels; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines

1996
Ischaemic skeletal muscle hyperaemia in the anaesthetized cat: no contribution of A2A adenosine receptors.
    The Journal of physiology, 1997, Apr-01, Volume: 500 ( Pt 1)

    Topics: Anesthesia, General; Animals; Blood Pressure; Cats; Electric Stimulation; Femoral Nerve; Hindlimb; Hyperemia; Ischemia; Isometric Contraction; Male; Muscle Contraction; Muscle, Skeletal; Oxygen Consumption; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Regional Blood Flow; Sciatic Nerve; Triazines; Triazoles

1997
Effects of the nitric oxide-donor, GEA 3175, on guinea-pig airways.
    European journal of pharmacology, 1997, Jun-25, Volume: 329, Issue:2-3

    Topics: Acetylcholine; Animals; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Okadaic Acid; Peptides; Phosphoprotein Phosphatases; Potassium Channel Blockers; Trachea; Triazoles

1997
Influence of cytochrome P-450 inhibitors on endothelium-dependent nitro-L-arginine-resistant relaxation and cromakalim-induced relaxation in rat mesenteric arteries.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:6

    Topics: Acetylcholine; Animals; Benzopyrans; Biological Factors; Cromakalim; Cytochrome P-450 Enzyme Inhibitors; Fatty Acids, Unsaturated; Female; In Vitro Techniques; Mesenteric Arteries; Miconazole; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Norepinephrine; Proadifen; Pyrroles; Rats; Rats, Wistar; Triazoles; Vasodilator Agents

1997
Effect of Apafant on bronchial hyperresponsiveness and down-regulation of beta-adrenoceptors induced by endotoxin in guinea pigs.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:7

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Azepines; Binding Sites; Bronchial Hyperreactivity; Bronchodilator Agents; Cardiography, Impedance; Down-Regulation; Endotoxins; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Lipopolysaccharides; Lung; Male; Membranes; Muscle Contraction; Muscle Relaxation; Triazoles

1997
Affinity of the miotic drug, dapiprazole, at alpha 1-adrenoceptor subtypes A, B and D.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:11

    Topics: Adrenergic alpha-Antagonists; Animals; Drug Interactions; Guinea Pigs; Male; Miotics; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Rats; Receptors, Adrenergic, alpha; Spleen; Triazoles; Vas Deferens

1997
Studies on nonpeptide angiotensin II receptor antagonists. II. Synthesis and biological evaluation of 5H-pyrazolo[1,5-b][1,2,4]triazole derivatives with a C-linked oxygen functional group at the 6-position.
    Chemical & pharmaceutical bulletin, 1998, Volume: 46, Issue:2

    Topics: Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Blood Pressure; Crystallography, X-Ray; Dogs; Female; In Vitro Techniques; Male; Molecular Structure; Muscle Contraction; Muscle, Smooth, Vascular; Pyrazoles; Rabbits; Rats; Rats, Wistar; Structure-Activity Relationship; Triazoles

1998
New 1,2,3-triazole derivatives (ureas, amides, urethanes) with a potential biological interest.
    Bollettino chimico farmaceutico, 1998, Volume: 137, Issue:9

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Colon; Drug Screening Assays, Antitumor; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Triazoles

1998
Effects of histamine H2 receptor agonists and antagonists on the isolated guinea pig gallbladder.
    Fundamental & clinical pharmacology, 1999, Volume: 13, Issue:1

    Topics: Animals; Benzothiazoles; Dopamine Agents; Famotidine; Gallbladder; Guanidines; Guinea Pigs; Histamine; Histamine Agonists; Histamine H2 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Phenoxypropanolamines; Piperidines; Pyridines; Receptors, Histamine H2; Sincalide; Thiazoles; Triazoles

1999
Role of NO and PAF in the impairment of skeletal muscle contractility induced by TNF-alpha.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:6

    Topics: Animals; Azepines; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Phospholipases A; Platelet Activating Factor; S-Nitroso-N-Acetylpenicillamine; Stereoisomerism; Triazoles; Tumor Necrosis Factor-alpha

2000
SCH 58261, an A(2A) adenosine receptor antagonist, counteracts parkinsonian-like muscle rigidity in rats.
    Synapse (New York, N.Y.), 2001, Volume: 41, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Animals; Ankle Joint; Dopamine Agents; Dopamine Antagonists; Drug Combinations; Electromyography; Haloperidol; Levodopa; Male; Muscle Contraction; Muscle Rigidity; Muscle, Skeletal; Neostriatum; Neuroprotective Agents; Parkinsonian Disorders; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Reserpine; Triazoles

2001
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
    British journal of pharmacology, 2001, Volume: 134, Issue:2

    Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; Male; Mesocricetus; Muscle Contraction; Mutation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Theobromine; Theophylline; Triazines; Triazoles; Xanthines

2001
Analysis of the relationship between pharmacological inhibition of cyclic nucleotide phosphodiesterase and relaxation of canine tracheal smooth muscle.
    Biochemical pharmacology, 1979, Apr-15, Volume: 28, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Airway Resistance; Animals; Caffeine; Dogs; Etazolate; Female; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phosphodiesterase Inhibitors; Pyrazines; Theophylline; Trachea; Triazoles

1979
Pharmacological evaluation of delta2, 1,2,4-triazolin-5-one [1,3(4-m-chlorophenyl-1-piperazinyl)-propyl]-3,4-diethyl-hydrochloride (Etoperidone), a new potential antidepressant drug.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:2

    Topics: Analgesics; Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Body Temperature; Cats; Dogs; Drug Interactions; Female; Guinea Pigs; Hemodynamics; Hexobarbital; In Vitro Techniques; Lethal Dose 50; Male; Mice; Muscle Contraction; Piperazines; Rabbits; Rats; Sleep; Thirst; Triazoles

1979
Effect of derivatives of 3-(beta-aminoethyl)-1,2,4-triazole on the histamine H1- and H2-receptors.
    Pharmacology, 1977, Volume: 15, Issue:6

    Topics: Animals; Blood Pressure; Cats; Dogs; Gastric Juice; Guinea Pigs; Heart Atria; Ileum; Male; Muscle Contraction; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Secretory Rate; Triazoles

1977
[Pharmacological studies of cefatrizine (S-640P) (author's transl)].
    The Japanese journal of antibiotics, 1976, Volume: 29, Issue:1

    Topics: Anesthetics; Animals; Bile; Blood Coagulation; Blood Pressure; Cardiac Output; Cats; Central Nervous System; Cephalosporins; Common Bile Duct; Dogs; Gastric Juice; Gastric Mucosa; Gastrointestinal Motility; Guinea Pigs; Hemolysis; In Vitro Techniques; Mice; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Rabbits; Rats; Respiration; Triazoles; Urine

1976
Synthesis and antiallergy activity of [1,3,4]thiadiazolo[3,2-a]-1,2,3-triazolo[4,5-d]pyrimidin-9(3H)-one derivatives. II. 6-Alkyl- and 6-cycloalkylalkyl derivatives.
    Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:9

    Topics: Animals; Female; Guinea Pigs; Hypersensitivity; In Vitro Techniques; Lung; Muscle Contraction; Ovalbumin; Passive Cutaneous Anaphylaxis; Pyrimidines; Rats; Rats, Sprague-Dawley; SRS-A; Thiadiazoles; Triazoles; X-Ray Diffraction

1992
MDL 27,531 reduces spontaneous hindlimb contractions in rats with chronic transections of the spinal cord.
    Neuroscience letters, 1992, Nov-23, Volume: 147, Issue:1

    Topics: Animals; Anticonvulsants; Clonidine; Decerebrate State; Hindlimb; Male; Muscle Contraction; Muscle Tonus; Postural Balance; Rats; Triazoles

1992
Synthesis, structure and biological activity of 1,2,4-triazolo-1,3-thiazine derivatives.
    Die Pharmazie, 1992, Volume: 47, Issue:10

    Topics: Animals; Antitubercular Agents; Cardiotonic Agents; Cardiovascular Agents; Heart Rate; Male; Muscle Contraction; Rats; Rats, Wistar; Structure-Activity Relationship; Thiazines; Triazoles

1992
Effect of platelet-activating factor on porcine pulmonary blood vessels in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 344, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Calcimycin; Diterpenes; Eicosanoids; Ginkgolides; In Vitro Techniques; Lactones; Male; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pulmonary Circulation; Radioimmunoassay; SRS-A; Swine; Thromboxane B2; Triazoles

1991
Synthesis and pharmacological activity of 5-substituted-s-triazole-3-thiols.
    Die Pharmazie, 1991, Volume: 46, Issue:2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular Agents; Epinephrine; Heart; Heart Rate; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Sulfides; Thioglycolates; Triazoles

1991
Active cholesterol biosynthesis in cultured aortic smooth muscle cells: evolution during the life-span of the culture.
    Atherosclerosis, 1991, Volume: 86, Issue:2-3

    Topics: Animals; Aorta; Cell Survival; Cells, Cultured; Cholesterol; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Triazoles

1991
Antagonism of endotoxin-induced disruption of equine gastrointestinal motility with the platelet-activating factor antagonist WEB 2086.
    Journal of veterinary pharmacology and therapeutics, 1990, Volume: 13, Issue:4

    Topics: Animals; Azepines; Endotoxins; Gastrointestinal Motility; Heart Rate; Hematocrit; Horses; Leukocyte Count; Male; Muscle Contraction; Platelet Activating Factor; Stomach; Triazoles

1990
The action of platelet activating factor and its antagonism by WEB 2086 on human isolated airways.
    The European respiratory journal, 1990, Volume: 3, Issue:1

    Topics: Azepines; Bronchi; Histamine; Humans; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Triazines; Triazoles

1990
Effects of dapiprazole on contractile responses of guinea pig isolated ileum.
    Pharmacological research communications, 1987, Volume: 19, Issue:3

    Topics: Animals; Antipsychotic Agents; Calcium Chloride; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Piperazines; Potassium; Triazoles

1987
Platelet-activating factor-induced contraction of guinea-pig lung parenchymal strips: possible involvement of arachidonate metabolites.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:4

    Topics: Acetylcholine; Animals; Arachidonic Acids; Atropine; Azepines; Cyclooxygenase Inhibitors; Guinea Pigs; Hypnotics and Sedatives; In Vitro Techniques; Lipoxygenase Inhibitors; Lung; Male; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Thromboxane A2; Triazines; Triazoles

1988
[Effects of D,L-oxyfedrine and trapymine on the energy metabolism of vascular smooth muscle].
    Acta biologica et medica Germanica, 1973, Volume: 31, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Cattle; Coronary Circulation; Coronary Vessels; Energy Metabolism; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Phosphofructokinase-1; Propanolamines; Propiophenones; Pyrimidines; Triazoles

1973
[The connection between the influence on urease activity and the pharmacological effect of some drugs with cardiac and coronary activity].
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 195, Issue:1

    Topics: Amino Alcohols; Animals; Binding Sites; Cardanolides; Cardiac Glycosides; Cats; Coronary Circulation; Digitalis Glycosides; Enzyme Activation; Ethylamines; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Isoproterenol; Muscle Contraction; Papaverine; Propiophenones; Propylamines; Pyrimidines; Rats; Receptors, Drug; Triazoles; Urease; Vasodilator Agents

1972