triazoles has been researched along with Melanoma in 41 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (4.88) | 18.7374 |
1990's | 3 (7.32) | 18.2507 |
2000's | 6 (14.63) | 29.6817 |
2010's | 26 (63.41) | 24.3611 |
2020's | 4 (9.76) | 2.80 |
Authors | Studies |
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Fandzloch, M; Gubernator, J; Jaromin, A; Lewińska, A; Sitkowski, J; Wiśniewska, J; Wojtczak, A; Zaremba-Czogalla, M; Łakomska, I | 1 |
Farstad, IN; Flem-Karlsen, K; Flørenes, VA; Jacobsen, KD; McFadden, E; Mælandsmo, GM; Nyakas, M; Wernhoff, P | 1 |
Bürkel, F; Distel, L; Fietkau, R; Hecht, M; Heinzerling, L; Jost, T | 1 |
Li, J; Li, L; Meng, Y; Sun, Y; Wu, X | 1 |
Allison, JP; Amaria, R; Ashkin, E; Davis, RE; Devi, S; Hanash, SM; Heffernan, T; Huang, L; Hwu, P; Khong, H; Kuiatse, I; Liu, C; Lizee, G; Malu, S; Mbofung, RM; McKenzie, JA; Muller, FL; Peng, W; Proia, D; Roszik, J; Satani, N; Talukder, AH; Tieu, T; Tripathi, SC; Williams, L; Xu, C; Zhang, M | 1 |
Bailey, FP; Clarke, K; Coulson, JM; Coupland, SE; Eyers, PA; Falciani, F; Kalirai, H; Kenyani, J; Sacco, JJ; Shahidipour, H | 1 |
Bäurle, S; Fernández-Montalván, AE; Gelato, KA; Haendler, B; Héroult, M; Kalfon, E; Klingbeil, O; Lejeune, P; Lesche, R; Mönning, U; Rückert, T; Schöckel, L; Siegel, S; Toedling, J | 1 |
Brothers, SP; Camarena, V; Huff, TC; Liu, ZJ; Mustafi, S; Sant, DW; Volmar, CH; Wahlestedt, C; Wang, G | 1 |
Cheng, X; Zhao, B; Zhou, X | 1 |
Buchbinder, EL; Chen, T; Flaherty, KT; Giobbie-Hurder, A; Hodi, FS; Ibrahim, N; Jacene, HA; Lawrence, DP; Luke, JJ; McDermott, DF; Ott, PA; Shah, S; Sullivan, RJ | 1 |
Hodi, FS; Marmarelis, ME; Wu, X | 1 |
Baer, C; Breyssens, H; Brown, NR; Caballero, OL; Cebon, J; Endicott, J; Goding, CR; Hu, Y; John, T; Jones, EY; Kessler, BM; Knapp, S; Lu, M; Lu, X; Middleton, MR; Ratnayaka, I; Salter, V; Siebold, C; Sullivan, A; Sviderskaya, EV; Zhong, S | 1 |
Acquaviva, J; Bates, RC; He, S; Jimenez, JP; Proia, DA; Sang, J; Sequeira, M; Smith, DL; Zhang, C | 1 |
Abudayyeh, O; Barzily-Rokni, M; Cooper, ZA; Fisher, DE; Flaherty, KT; Frederick, DT; Garraway, LA; Hahn, WC; Haq, R; Johannessen, CM; Kim, JW; Konieczkowski, DJ; Mesirov, JP; Piris, A; Straussman, R; Tamayo, P; Wargo, JA | 1 |
Bentabed-Ababsa, G; Chevallier, F; Derdour, A; Dorcet, V; Hedidi, M; Mongin, F; Picot, L; Roisnel, T; Thiéry, V | 1 |
Beert, E; Bradner, J; Brems, H; Cichowski, K; Clapp, W; De Raedt, T; Helin, K; Hornick, JL; Kehrer-Sawatzki, H; Legius, E; Luscan, A; Mautner, V; Ortonne, N; Pasmant, E; Upadhyaya, M; Vidaud, M | 1 |
Andreucci, E; Bianchini, F; Bottoncetti, A; Calorini, L; Fabbrizzi, P; Guarna, A; Menchi, G; Passeri, A; Pupi, A; Raspanti, S; Trabocchi, A | 1 |
Sahu, RP | 1 |
Buijsman, RC; de Man, J; de Roos, JA; de Vetter, JR; Prinsen, MB; Spijkers-Hagelstein, JA; Uitdehaag, JC; van Doornmalen, AM; Zaman, GJ | 1 |
Ambrosini, G; Musi, E; Sawle, AD; Schwartz, GK | 1 |
Bradner, JE; Darvishian, F; Hanniford, D; Hernando, E; Osman, I; Paoluzzi, L; Sokolova, E; Wang, J | 1 |
Beltran, P; Caenepeel, S; Cajulis, E; Cooke, K; Coxon, A; Huang, G; Hughes, PE; Kendall, R; Moreno, BH; Parisi, G; Ribas, A; Robert, L; Wadsworth, S | 1 |
Cowen, EW; Fox, LP; McCalmont, TH; Miller, DD; Nguyen, JC | 1 |
Bianchini, F; Bottoncetti, A; Calorini, L; Cini, N; Guarna, A; Menchi, G; Pupi, A; Raspanti, S; Trabocchi, A | 1 |
Ashton, S; Barry, ST; Blakey, D; Lewis, CE; Murdoch, C; Tazzyman, S; Wood, P | 1 |
Brown, M; O'Reilly Zwald, F | 1 |
Alciato, F; Anichini, A; Avanzi, G; Bersani, I; Canevari, S; Castellano, G; Catani, M; De Santis, G; Nicolini, G; Sensi, M; Tomassetti, A; Tragni, G | 1 |
Blanche, S; Chosidow, O; Epaulard, O; Leccia, MT; Lortholary, O; Mamzer-Bruneel, MF; Ravaud, P; Thiebaut, A; Villier, C | 1 |
Schmutz, JL; Trechot, P | 1 |
Chammas, R; Jancar, S; Machado, CM; Onuchic, AC; Rios, FJ; Saito, RF | 1 |
Desai, S; Kohn, EC; Libutti, SK; Lorang, D; Oliver, VK; Patton, AM | 1 |
Baraldi, PG; Borea, PA; Capitani, S; Gessi, S; Leung, E; Merighi, S; Mirandola, P; Tabrizi, MA; Varani, K | 1 |
Konovalova, NP | 1 |
Connolly, PJ; Emanuel, S; Fuentes-Pesquera, A; Gruninger, RH; Hollister, B; Jolliffe, L; Kruger, WW; Lin, R; Middleton, SA; Napier, C; Rugg, CA; Wetter, SK | 1 |
Calorini, L; Fallani, A; Gabellieri, S; Mannini, A; Mugnai, G; Ruggieri, S | 1 |
DiLeonardo, M; Gibbons, G; Resnik, KS | 1 |
Alonso, G; Alonso, R; Camarasa, MJ; Contreras, A; de las Heras, FG; García López, MT; Herranz, R; Sánchez-Pérez, RM | 1 |
Bielenberg, D; Fidler, IJ; Huang, S; Jiang, W; McConkey, DJ; Salas, T; Wang, Y; Xie, K; Xu, L | 1 |
Kohn, EC; Liotta, LA; Sandeen, MA | 1 |
Baba, I; Hayashi, Y; Katagiri, Y; Suzuki, H; Tanoue, K; Yamazaki, H | 1 |
Abele, R; Cavalli, F; Clavel, M; Dodion, P; Gundersen, S; Renard, G; van Glabbeke, M | 1 |
3 review(s) available for triazoles and Melanoma
Article | Year |
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Kinome-wide transcriptional profiling of uveal melanoma reveals new vulnerabilities to targeted therapeutics.
Topics: Azepines; Cell Cycle Proteins; Cell Line, Tumor; Computational Biology; Down-Regulation; Forkhead Box Protein M1; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Melanoma; Molecular Targeted Therapy; Nuclear Proteins; Protein Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-myc; RNA, Messenger; Signal Transduction; Transcription Factors; Transcriptome; Triazoles; Uveal Neoplasms | 2018 |
Skin cancer in solid organ transplant recipients: advances in therapy and management: part I. Epidemiology of skin cancer in solid organ transplant recipients.
Topics: Carcinoma, Basal Cell; Carcinoma, Merkel Cell; Carcinoma, Squamous Cell; Education, Medical, Continuing; Female; Humans; Immunocompromised Host; Incidence; Male; Melanoma; Organ Transplantation; Prognosis; Pyrimidines; Risk Assessment; Sarcoma, Kaposi; Sirolimus; Skin Neoplasms; Survival Analysis; Treatment Outcome; Triazoles; Voriconazole | 2011 |
Phototoxicity and photocarcinogenesis associated with voriconazole.
Topics: Antifungal Agents; Biotransformation; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cocarcinogenesis; Comorbidity; Dermatitis, Phototoxic; Drug Interactions; Humans; Immunocompromised Host; Melanoma; Mycoses; Neoplasms, Radiation-Induced; Photochemistry; Postoperative Complications; Pyrimidines; Retinoids; Retrospective Studies; Skin Neoplasms; Sunlight; Transplantation; Triazoles; Voriconazole | 2011 |
1 trial(s) available for triazoles and Melanoma
Article | Year |
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Results from phase II trial of HSP90 inhibitor, STA-9090 (ganetespib), in metastatic uveal melanoma.
Topics: Adult; Aged; Aged, 80 and over; Female; HSP90 Heat-Shock Proteins; Humans; Male; Melanoma; Middle Aged; Skin Neoplasms; Triazoles; Uveal Neoplasms | 2018 |
37 other study(ies) available for triazoles and Melanoma
Article | Year |
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Nanoencapsulation of a ruthenium(ii) complex with triazolopyrimidine in liposomes as a tool for improving its anticancer activity against melanoma cell lines.
Topics: Antineoplastic Agents; Capsules; Cell Line, Tumor; Coordination Complexes; Humans; Hydrophobic and Hydrophilic Interactions; Liposomes; Melanoma; Nanostructures; Pyrimidines; Ruthenium; Triazoles | 2020 |
Soluble AXL as a marker of disease progression and survival in melanoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Immunological; Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Biomarkers, Tumor; Cell Line, Tumor; Disease Progression; Female; Humans; Ipilimumab; Male; Melanoma; Middle Aged; Neoplasm Staging; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Skin Neoplasms; Solubility; Survival Rate; Triazoles | 2020 |
Dual mTOR/DNA-PK Inhibitor CC-115 Induces Cell Death in Melanoma Cells and Has Radiosensitizing Potential.
Topics: Cell Death; Cell Line; Cell Line, Tumor; DNA-Activated Protein Kinase; Fibroblasts; Homologous Recombination; Humans; Melanoma; Protein Kinase Inhibitors; Pyrazines; Radiation Tolerance; TOR Serine-Threonine Kinases; Triazoles | 2020 |
Bromodomain-containing protein 4 inhibitor JQ1 promotes melanoma cell apoptosis by regulating mitochondrial dynamics.
Topics: AMP-Activated Protein Kinases; Apoptosis; Azepines; Cell Cycle Proteins; Cell Respiration; Dynamins; Electron Transport Chain Complex Proteins; Energy Metabolism; Enzyme Activation; Female; Fusion Regulatory Protein-1; Humans; Melanoma; Melanoma, Experimental; Mitochondria; Oxidative Stress; Protein Subunits; Proto-Oncogene Proteins c-myc; Reactive Oxygen Species; Skin Neoplasms; Transcription Factors; Triazoles | 2021 |
HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes.
Topics: Animals; Cell Line, Tumor; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Immunotherapy; Interferons; Ipilimumab; Kaplan-Meier Estimate; Melanoma; Mice, Inbred C57BL; T-Lymphocytes; Triazoles; Tumor Burden; Up-Regulation; Xenograft Model Antitumor Assays | 2017 |
Super-enhancers define a proliferative PGC-1α-expressing melanoma subgroup sensitive to BET inhibition.
Topics: Animals; Antineoplastic Agents; Azepines; Benzodiazepines; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Enhancer Elements, Genetic; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Mice; Mice, Inbred C57BL; Mice, Nude; Mitochondria; Nuclear Proteins; Patient Selection; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Binding; Skin Neoplasms; SOXE Transcription Factors; Transcription Factors; Treatment Outcome; Triazoles; Xenograft Model Antitumor Assays | 2018 |
Vitamin C Sensitizes Melanoma to BET Inhibitors.
Topics: Acetylation; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Azepines; Biomarkers, Tumor; Cell Proliferation; Drug Combinations; Drug Synergism; Gene Expression Regulation, Neoplastic; Histones; Humans; Melanoma; Mice; Mice, Inbred C57BL; Mice, Nude; Protein Domains; Proteins; Triazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2018 |
The BET-bromodomain inhibitor JQ1 mitigates vemurafenib drug resistance in melanoma.
Topics: Animals; Antineoplastic Agents; Azepines; Drug Resistance, Neoplasm; Humans; Melanoma; Mice; Proto-Oncogene Proteins B-raf; Triazoles; Vemurafenib | 2018 |
Activity of the heat shock protein 90 inhibitor ganetespib in melanoma.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; GTP Phosphohydrolases; HSP90 Heat-Shock Proteins; Humans; Immunoblotting; Inhibitory Concentration 50; Melanoma; Membrane Proteins; Mutation; Phosphorylation; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Skin Neoplasms; Triazoles | 2013 |
Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP.
Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cyclin B1; Dimerization; Humans; Imidazoles; Indoles; Intracellular Signaling Peptides and Proteins; M Phase Cell Cycle Checkpoints; Melanoma; Mice; Neoplasm Metastasis; Nocodazole; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-mdm2; Repressor Proteins; Sulfonamides; Triazoles; Tumor Suppressor Protein p53; Vemurafenib; Xenograft Model Antitumor Assays | 2013 |
Overcoming acquired BRAF inhibitor resistance in melanoma via targeted inhibition of Hsp90 with ganetespib.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Blotting, Western; Cell Line, Tumor; Cell Survival; Cells, Cultured; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; HSP90 Heat-Shock Proteins; Humans; Indoles; Melanoma; Mice, Nude; Mice, SCID; Mitogen-Activated Protein Kinase Kinases; Mutation; Proto-Oncogene Proteins B-raf; Pyridones; Pyrimidinones; Sulfonamides; Triazoles; Vemurafenib; Xenograft Model Antitumor Assays | 2014 |
A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors.
Topics: Anilides; Benzimidazoles; Benzocycloheptenes; Cell Line, Tumor; Cells, Cultured; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; Indoles; MAP Kinase Signaling System; Melanocytes; Melanoma; Microphthalmia-Associated Transcription Factor; NF-kappa B p50 Subunit; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-met; Pyridines; Quinolines; Sulfonamides; Triazoles | 2014 |
Synthesis of C,N'-linked bis-heterocycles using a deprotometalation-iodination-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Humans; Iodides; Melanoma; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Triazoles | 2014 |
PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies.
Topics: Animals; Azepines; Cell Cycle Proteins; Cell Death; Chromatin; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioma; Humans; Melanoma; Mice; Mitogen-Activated Protein Kinase Kinases; Neoplasm Proteins; Neoplasms; Nerve Sheath Neoplasms; Neurofibromin 1; Nuclear Proteins; Polycomb Repressive Complex 2; ras Proteins; Transcription Factors; Transcription, Genetic; Triazoles; Tumor Suppressor Proteins | 2014 |
Radiosynthesis and micro-SPECT analysis of triazole-based RGD integrin ligands as non-peptide molecular imaging probes for angiogenesis.
Topics: Animals; Heterografts; Humans; Integrins; Ligands; Melanoma; Mice; Models, Molecular; Molecular Probes; Neovascularization, Pathologic; Oligopeptides; Tomography, Emission-Computed, Single-Photon; Triazoles | 2015 |
Expression of the platelet-activating factor receptor enhances benzyl isothiocyanate-induced apoptosis in murine and human melanoma cells.
Topics: Animals; Apoptosis; Azepines; Cell Line; Cell Proliferation; Gene Expression Regulation; Humans; Isothiocyanates; Melanoma; Mice; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Signal Transduction; Triazoles | 2015 |
Selective Targeting of CTNBB1-, KRAS- or MYC-Driven Cell Growth by Combinations of Existing Drugs.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aza Compounds; Benzimidazoles; beta Catenin; Cell Line, Tumor; Cell Proliferation; Humans; Imidazoles; Indazoles; Indoles; Melanoma; Molecular Targeted Therapy; Mutation; Oxazoles; Oximes; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins p21(ras); Pyridones; Pyrimidinones; Quinolines; Sulfonamides; Triazoles; Vemurafenib | 2015 |
BRD4-targeted therapy induces Myc-independent cytotoxicity in Gnaq/11-mutatant uveal melanoma cells.
Topics: Animals; Azepines; Cell Death; Genes, myc; GTP-Binding Protein alpha Subunits; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Melanoma; Mice; Mice, SCID; Molecular Targeted Therapy; Nuclear Proteins; Transcription Factors; Triazoles; Tumor Cells, Cultured; Uveal Neoplasms; Xenograft Model Antitumor Assays | 2015 |
BET and BRAF inhibitors act synergistically against BRAF-mutant melanoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azepines; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; Humans; Indoles; Melanoma; Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Sulfonamides; Transcription, Genetic; Triazoles; Vemurafenib; Xenograft Model Antitumor Assays | 2016 |
MAPK pathway inhibition induces MET and GAB1 levels, priming BRAF mutant melanoma for rescue by hepatocyte growth factor.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Benzamides; Cell Line, Tumor; Dipeptides; Diphenylamine; Drug Resistance, Neoplasm; Female; Hepatocyte Growth Factor; Humans; Indoles; MAP Kinase Signaling System; Melanoma; Mice; Mice, Nude; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-met; Pyridones; Sulfonamides; Triazoles; Vemurafenib; Xenograft Model Antitumor Assays | 2017 |
Melanoma associated with long-term voriconazole therapy: a new manifestation of chronic photosensitivity.
Topics: Adult; Antifungal Agents; Biopsy; Chronic Disease; Coccidioidomycosis; Diagnosis, Differential; Ear; Female; Follow-Up Studies; Forearm; Granulomatous Disease, Chronic; Humans; Male; Melanoma; Meningitis, Fungal; Photosensitivity Disorders; Pyrimidines; Skin Neoplasms; Time Factors; Triazoles; Voriconazole; Young Adult | 2010 |
Click-chemistry-derived triazole ligands of arginine-glycine-aspartate (RGD) integrins with a broad capacity to inhibit adhesion of melanoma cells and both in vitro and in vivo angiogenesis.
Topics: Alkynes; Angiogenesis Inhibitors; Animals; Azides; Cell Adhesion; Cell Line, Tumor; Drug Screening Assays, Antitumor; Endothelial Cells; Extracellular Matrix Proteins; Humans; Integrin alphaVbeta3; Ligands; Melanoma; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Mimicry; Neovascularization, Pathologic; Oligopeptides; Phenylpropionates; Protein Binding; Radioligand Assay; Receptors, Vitronectin; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2010 |
Inhibition of neutrophil infiltration into A549 lung tumors in vitro and in vivo using a CXCR2-specific antagonist is associated with reduced tumor growth.
Topics: Adenocarcinoma; Animals; Blotting, Western; Cell Proliferation; Chemotaxis; Culture Media, Conditioned; Enzyme-Linked Immunosorbent Assay; Humans; Immunoenzyme Techniques; In Vitro Techniques; Lung Neoplasms; Melanoma; Mice; Mice, Inbred BALB C; Mice, SCID; Neutrophil Infiltration; Quinazolines; Receptors, Interleukin-8B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spheroids, Cellular; Triazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2011 |
Human cutaneous melanomas lacking MITF and melanocyte differentiation antigens express a functional Axl receptor kinase.
Topics: Antigens, Differentiation; Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Gene Knockdown Techniques; Humans; Melanoma; Melanoma-Specific Antigens; Microphthalmia-Associated Transcription Factor; Mutation; Neoplasm Invasiveness; Proto-Oncogene Proteins; Proto-Oncogene Proteins B-raf; Receptor Protein-Tyrosine Kinases; Skin Neoplasms; Triazoles | 2011 |
[Careful: skins cancers and voriconazole].
Topics: Adult; Antifungal Agents; Carcinoma, Squamous Cell; Dermatitis, Phototoxic; Drug Eruptions; Female; Humans; Male; Melanoma; Photosensitizing Agents; Pyrimidines; Skin Aging; Skin Neoplasms; Triazoles; Voriconazole; Young Adult | 2011 |
Expression of PAFR as part of a prosurvival response to chemotherapy: a novel target for combination therapy in melanoma.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azepines; Cell Line, Tumor; Cell Survival; Cisplatin; Female; Gene Expression Regulation, Neoplastic; Humans; Macrophages; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Triazoles | 2012 |
Regulation of the pro-angiogenic microenvironment by carboxyamido-triazole.
Topics: Animals; Antineoplastic Agents; Cell Movement; Cell Transplantation; Culture Media; Endothelial Growth Factors; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hydrogen-Ion Concentration; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Interleukin-8; Lymphokines; Melanoma; Mice; Neovascularization, Pathologic; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Transplantation, Heterologous; Triazoles; Tumor Cells, Cultured; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
Pyrazolotriazolopyrimidine derivatives sensitize melanoma cells to the chemotherapic drugs: taxol and vindesine.
Topics: Antineoplastic Agents; Cell Cycle; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Keratinocytes; Melanoma; Paclitaxel; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A3; Triazoles; Tumor Cells, Cultured; Vindesine | 2003 |
Ultralow doses of various drugs in chemotherapy of experimental tumors.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Indazoles; Leukemia P388; Lung Neoplasms; Melanoma; Mice; Mitomycin; Neoplasm Metastasis; Neoplasms, Experimental; Triazoles; Xenograft Model Antitumor Assays | 2003 |
The in vitro and in vivo effects of JNJ-7706621: a dual inhibitor of cyclin-dependent kinases and aurora kinases.
Topics: Animals; Aurora Kinases; Cell Line, Tumor; Cells, Cultured; Cyclin-Dependent Kinases; Endothelial Cells; Female; HeLa Cells; Humans; Melanoma; Mice; Mice, Nude; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Triazoles; Xenograft Model Antitumor Assays | 2005 |
Platelet-activating factor (PAF) is the effector of IFN gamma-stimulated invasiveness and motility in a B16 melanoma line.
Topics: Animals; Azepines; Cell Movement; Collagen; Culture Media, Conditioned; Drug Combinations; Interferon-gamma; Laminin; Melanoma; Mice; Neoplasm Invasiveness; Phenotype; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Proteoglycans; Receptors, G-Protein-Coupled; Stress Fibers; Time Factors; Triazoles; Tumor Cells, Cultured | 2006 |
Clinically occult cutaneous metastases.
Topics: Aged; Aged, 80 and over; Anastrozole; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Breast Neoplasms; Capecitabine; Carcinoma; Carcinoma, Basal Cell; Carcinoma, Lobular; Carcinoma, Signet Ring Cell; Deoxycytidine; Estradiol; Facial Neoplasms; Female; Fluorouracil; Fulvestrant; Humans; Incidental Findings; Letrozole; Mastectomy, Radical; Megestrol Acetate; Melanoma; Neoplasms, Second Primary; Neoplastic Cells, Circulating; Nitriles; Selective Estrogen Receptor Modulators; Skin Neoplasms; Tamoxifen; Triazoles; Wound Healing | 2006 |
[Synthesis, cytostatic activity and mechanism of action of N-glycosylhalomethylazoles. A new class of alkylating agents].
Topics: Alkylating Agents; Animals; Carcinoma, Ehrlich Tumor; Imidazoles; In Vitro Techniques; Leukemia P388; Leukemia, Experimental; Melanoma; Monosaccharides; Pyrazoles; Triazoles | 1982 |
Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with downregulation of Bcl-2.
Topics: Animals; Apoptosis; DNA Fragmentation; Down-Regulation; Genetic Vectors; Interferon-gamma; Interleukin-1; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C3H; Mice, Nude; Nitric Oxide; Proto-Oncogene Proteins c-bcl-2; Transfection; Triazoles; Tumor Cells, Cultured | 1997 |
In vivo efficacy of a novel inhibitor of selected signal transduction pathways including calcium, arachidonate, and inositol phosphates.
Topics: Aminoimidazole Carboxamide; Animals; Antineoplastic Agents; Arachidonic Acids; Calcium; Cell Division; Cell Line; Cell Transformation, Neoplastic; Colonic Neoplasms; Female; Genes, ras; Humans; Inositol Phosphates; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Rats; Signal Transduction; Transfection; Transplantation, Heterologous; Triazoles | 1992 |
Characterization of platelet aggregation induced by the human melanoma cell line HMV-I: roles of heparin, plasma adhesive proteins, and tumor cell membrane proteins.
Topics: Antibodies, Monoclonal; Azepines; Blood Coagulation Factors; Calcium; Cells, Cultured; Citrates; Citric Acid; Fibrinogen; Flow Cytometry; Heparin; In Vitro Techniques; Magnesium; Melanoma; Membrane Proteins; Microbial Collagenase; Neuraminidase; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Thrombospondins; Triazoles; Trypsin | 1991 |
Phase II trial of triglycidylurazol (TGU) in advanced malignant melanoma.
Topics: Aged; Drug Evaluation; Humans; Melanoma; Triazoles | 1987 |