triazoles has been researched along with Lung Neoplasms in 172 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (4.65) | 18.7374 |
| 1990's | 5 (2.91) | 18.2507 |
| 2000's | 31 (18.02) | 29.6817 |
| 2010's | 106 (61.63) | 24.3611 |
| 2020's | 22 (12.79) | 2.80 |
| Authors | Studies |
|---|---|
| Carter, BW; Colen, R; Fu, S; Gong, J; Hong, DS; Janku, F; Karp, DD; McQuinn, L; Meric-Bernstam, F; Milton, DR; Naing, A; Piha-Paul, SA; Shah, J; Stephen, BA; Sulovic, S; Thein, KZ; Tsimberidou, A; Yap, TA | 1 |
| Cha, SI; Cho, S; Choi, JE; Choi, SH; Do, SK; Hong, MJ; Jheon, S; Kang, HG; Kim, CH; Lee, EB; Lee, J; Lee, JH; Lee, SY; Lee, WK; Lee, YH; Park, JY; Seo, H; Yoo, SS | 1 |
| Cai, KY; He, XH; Li, ZW; Liu, KQ; Sun, XY; Wang, X; Zhao, YC; Zhi, TX | 1 |
| Biegański, P; Godel, M; Kawano, DF; Kopecka, J; Kowalski, K; Riganti, C | 1 |
| Chen, L; Chen, W; Li, L | 1 |
| Cho, I; Choi, J; Park, J; Sheen, Y | 1 |
| Chen, M; Dong, J; Gao, Y; Liu, W; Wang, T; Zhu, D | 1 |
| Biegański, P; Dmitrieva, E; Godel, M; Israel, N; Kopecka, J; Kovalski, E; Kowalski, K; Lang, H; Riganti, C; Trzybiński, D; Vrček, V; Woźniak, K | 1 |
| Bagiński, M; Bartoszewski, R; Dąbrowska, AM; Filip-Psurska, B; Gawrońska, M; Krzymiński, K; Milczarek, M; Moszyńska, A; Psurski, M; Świtalska, M; Wietrzyk, J | 1 |
| Castellano, GM; Garbuzenko, OB; Malhotra, J; Minko, T; Pine, SR; Sabaawy, HE; Zeeshan, S | 1 |
| Beattie, D; Cadogan, EB; Cairns, J; Davies, BR; Dean, E; Farrington, PM; Fawell, SE; Finlay, MRV; Fok, JHL; Follia, V; Goldberg, FW; Hollingsworth, SJ; James, N; Karmokar, A; Lamont, GM; Ling, S; Nikkilä, J; O'Connor, LO; O'Connor, MJ; Ramos-Montoya, A; Smith, A; Vazquez-Chantada, M; Wijnhoven, PWG; Willis, SE; Wilson, J | 1 |
| Arunrungvichian, K; Doungchawee, J; Pongrakhananon, V; Pothongsrisit, S; Vajragupta, O; Witayateeraporn, W | 1 |
| Fernandez, E; Makar, G; Perz, A; Rafferty, W; Weinstock, J | 1 |
| Cavalcante, GC; Gu, J; He, X; Owonikoko, TK; Sun, SY; Wang, S; Yao, W; Zhang, G; Zong, D | 1 |
| Boyce, BF; Duan, R; Huston, A; Lei, W; Li, J; Liu, X; Yao, Z | 1 |
| Byers, LA; Cardnell, RJ; Diao, L; Fowlkes, NW; Fradette, JJ; Gibbons, DL; Gibson, L; Konen, JM; Kovacs, JJ; Ochieng, JK; Padhye, A; Peng, DH; Rodriguez, BL; Wang, J | 1 |
| Bie, Z; Chen, J; Dong, Z; Huang, D; Jiang, R; Jiang, X; Li, L; Li, M; Lin, L; Liu, Z; Meng, Z; Qin, T; Sun, T; Wang, J; Wang, L; Yang, G; Yu, J; Zhang, C; Zhang, M; Zhang, Y | 1 |
| Chen, J; Cheng, Z; Luo, J; Meng, Y; Sun, T; Wang, X; Xia, B; Zhang, Z; Zhou, X | 1 |
| Banerjee, T; Gross, RA; Naz, S; Santra, S; Totsingan, F; Woody, K | 1 |
| Araújo, HM; Flávia do Amaral Moura, C; Gonçalves Ferreira, VP; Lapa Montenegro Pimentel, LM; Melo de Oliveira, VN; Nascimento de Oliveira, R; Nicolete, R; Peixoto, ADS; Pena, LJ; Pessoa, CDÓ; Rathi, B; Rollin, P; Sharma, PP; Tatibouët, A; Versiani Dos Anjos, J | 1 |
| Hu, X; Shi, L; Wang, Z; Xie, C; Xiong, Y | 1 |
| Chen, C; Chen, W; Guo, L; Ju, R; Li, J; Shi, J; Sun, F; Ye, C; Zhang, D; Zhu, L | 1 |
| Beltran, H; Demichelis, F; Rickman, DS; Rubin, MA | 1 |
| Colangelo, D; Osella, D; Zanellato, I | 1 |
| Bősze, S; Csámpai, A; Dinić, J; Hudecz, F; Kocsis, L; Pešić, M; Podolski-Renić, A | 1 |
| Debiane, LG; Jimenez, CA; Landaeta, M; Vial, M | 1 |
| Bajić, M; Bistrović, A; Grbčić, P; Harej, A; Koštrun, S; Krstulović, L; Pavelić, SK; Raić-Malić, S; Sedić, M | 1 |
| Dasu, A; Even, AJG; Lambin, P; Lindblom, E; Toma-Dasu, I; Uhrdin, J; Ureba, A; van Elmpt, W; Wersäll, P | 1 |
| Chiu, CC; Fang, K; Hsieh, CH; Liu, CY; Wang, JP; Yao, CF | 1 |
| Bistrović, A; Grbčić, P; Harej, A; Koštrun, S; Kraljević-Pavelić, S; Makuc, D; Plavec, J; Raić-Malić, S; Sedić, M | 1 |
| Alessandrini, G; Amoreo, CA; Blandino, G; Ciliberto, G; Cioce, M; De Maria, R; di Martino, S; Facciolo, F; Galati, R; Nuvoli, B; Pass, HI; Strano, S | 1 |
| Cheng, Z; Gao, Z; Li, P; Ni, P; Sun, G; Wang, X; Yuan, T; Zhou, X | 1 |
| Burns, TF; Chatterjee, S; Goldstein, LA; Han, J; Hou, W; Rabinowich, H | 1 |
| Abbas, SH; Abd El-Hafeez, AA; Abdel-Aziz, M; Abdelhamid, D; Ahmed, FF | 1 |
| Adeegbe, DO; Bradner, JE; Buczkowski, K; Chen, T; Christensen, CL; Dries, R; Gao, P; Hammerman, PS; Han, S; Li, F; Li, Y; Liu, S; Liu, Y; Quayle, SN; Quinn, MM; Wang, X; Wong, KK; Zhang, H | 1 |
| Hussaini, SMQ; Madut, D; Pavlisko, EN; Perfect, JR; Schell, WA; Thielman, NM; Tong, BC | 1 |
| Handoko, L; Hon, CC; Ito, T; Jeyamohan, P; Kaczkowski, B; Kimura, H; Lizio, M; Matsuda, T; Minoda, A; Sakamoto, K; Sato, Y; Umehara, T; Wakamori, M; Yokoyama, S | 1 |
| Adeegbe, DO; Bass, AJ; Bowden, M; Bradner, JE; Chen, H; Diehl, JA; Dolgalev, I; Freeman, GJ; Gao, P; Grondine, M; Hammerman, PS; Hattersley, MM; Ivanova, EV; Li, S; Liu, S; Quinn, MM; Rustgi, AK; Tsirigos, A; Vlahos, R; Wong, KK; Zhou, CW | 1 |
| Fujino, N; Fujishima, F; Ichinose, M; Inoue, A; Itakura, K; Kyogoku, Y; Miyauchi, E; Okada, Y; Okazaki, T; Okutomo, K; Saito, R; Sugiura, H; Tsukita, Y; Yamada, M | 1 |
| Banerjee, T; Darji, S; Fletcher, C; Gerasimchuk, NN; Higginbotham, R; Kallu, J; Santra, S; Sulthana, S | 1 |
| Kurihara, E; Namba, K; Ogoshi, Y; Okazaki, M; Sato, H; Shien, K; Shien, T; Soh, J; Suzawa, K; Takahashi, Y; Takeda, T; Tomida, S; Torigoe, H; Toyooka, S; Yamamoto, H; Yoshioka, T | 1 |
| Liu, JW; Xiong, ZQ; Yang, C; Zhao, M; Zhu, ZC | 1 |
| An, P; Chen, Z; Chiang, CM; Du, J; Li, W; Lin, X; Lu, L; Shan, H; Su, Q; Tian, L; Wang, H; Wu, Y | 1 |
| Boran, A; Chen, Y; Gallo, J; Goldfarb, J; Hu, Y; Iyengar, R; Jayaraman, G; Li, L; Mariottini, C; Tavassoly, I; Tolentino, RE; Zhao, S | 1 |
| Dosaka-Akita, H; Furuta, M; Kikuchi, E; Kikuchi, H; Kikuchi, J; Kinoshita, I; Konno, S; Maeda, M; Sakakibara-Konishi, J; Shoji, T; Suzuki, M; Takashima, Y | 1 |
| Akca, H; Alvur, O; Baygu, Y; Gok, Y; Kabay, N; Tokgun, O | 1 |
| Jin, CH; Li, ZW; Liu, MY; Qiu, QQ; Sun, XY; Wang, X; Zhong, CY | 1 |
| Bender, A; Bharathkumar, H; Bhatnagar, R; Keerthy, HK; Mohan, CD; Mohan, S; Rangappa, KS; Rangappa, S; Svensson, F | 1 |
| Cobb, MH; Ding, Q; Hu, R; Huffman, KE; Johnson, JE; Minna, JD; Savage, TK; Wang, XD; Williams, N; Yu, Y | 1 |
| Acquaviva, J; Bates, RC; Camidge, DR; Doebele, RC; El-Hariry, I; Friedland, JC; He, S; Jiang, Q; Jimenez, JP; Lovly, CM; Morris, SW; Proia, DA; Sang, J; Sequeira, M; Shaw, AT; Smith, DL; Xue, L; Zhang, C | 1 |
| Belani, CP; Bonomi, P; Brahmer, J; Chen, LC; El-Hariry, I; Goldman, J; Guo, W; Harper, H; Horn, L; Huberman, M; Koczywas, M; Paschold, E; Ramalingam, S; Salgia, R; Sandler, A; Sequist, LV; Shapiro, GI; Socinski, MA; Teofilovici, F; Vukovic, V; Webb, T; West, H; Wong, KK | 1 |
| Aibe, N; Kagiya, T; Kimoto, T; Kodani, N; Koizumi, M; Nakamura, S; Nishimura, T; Sihomi, H; Tsubokura, T; Yamazaki, H; Yoshida, K | 1 |
| Cheng, Q; Jia, H; Li, D; Li, L; Zhang, G; Zhao, M; Zhao, T; Zheng, J | 1 |
| da Trindade, MC; de Menezes, AI; de Souza, DW; Dos Santos, VM; Nascimento, AL; Oguma, PM | 1 |
| Essenburg, C; Kaufman, D; Lewis, S; Staal, B; Vande Woude, GF; Zhang, YW | 1 |
| Cary, DR; Hori, A; Imamura, S; Iwata, H; Miki, H; Miyamoto, N; Oguro, Y; Tawada, M | 1 |
| Antonia, SJ; Khalil, FK; Luddy, K; Mediavilla-Varela, M; Neuger, AM; Noyes, D; Soliman, H | 1 |
| Brans, B; De Ruysscher, D; Eriksson, J; Hoebers, F; Lambin, P; Mottaghy, FM; Öllers, MC; Reymen, B; Sharifi, H; Troost, EG; van Baardwijk, A; van Elmpt, W; Wanders, R; Wierts, R; Windhorst, B; Zegers, CM | 1 |
| Akbay, E; Bradner, JE; Carretero, J; Chen, Z; Cheng, KA; Cohoon, TJ; Gao, Y; Kikuchi, E; Kimmelman, AC; Kung, AL; Qi, J; Shimamura, T; Soucheray, M; Tchaicha, JH; Wong, KK | 1 |
| Alberobello, AT; Giaccone, G; Lai, CH; Lee, DH; Park, KS; Petricoin Iii, EF; Pierobon, M; Pin, E; Raffeld, M; Wang, Y | 1 |
| Acquaviva, J; Bates, RC; El-Hariry, I; He, S; Jimenez, JP; Nagai, M; Proia, DA; Sang, J; Sequeira, M; Shapiro, GI; Smith, DL; Spector, N; Tolaney, S; Zhang, C | 1 |
| Baxi, SM; Estrella, H; Li, C; Liu, KK; Mehta, PP; Smeal, T; Walls, M; Yin, MJ; Zhu, J; Zientek, M; Zong, Q | 1 |
| Yaqub, F | 1 |
| Pillai, RN; Ramalingam, SS | 1 |
| Guo, RT; Li, XL; Li, Y; Luan, JW; Nie, D; Wu, J; You, QS; Zhang, LP | 1 |
| Acquaviva, J; Bates, RC; He, S; Proia, DA; Sang, J; Sequeira, M; Smith, DL; Zhang, C | 1 |
| Han, X; Shi, Y; Wang, J; Wang, S; Yao, J | 1 |
| George, S; Nucci, MR; Raut, CP; Serrano, C; Tirumani, SH | 1 |
| Kim, DK; Kim, MJ; Kim, SJ; Kim, SW; Lee, SJ; Nam, JS; Park, SA; Park, SY; Sheen, YY; Son, JY | 1 |
| Agrawal, A; Cheung, KL; Gutteridge, E; Marenah, C; Mathew, J; Prinsloo, P; Robertson, JF | 1 |
| Abel, ML; Hruban, RH; Iacobuzio-Donahue, CA; Kim, MS; Maitra, A; Marimuthu, A; Mudgal, K; Pandey, A; Poling, JS; Rajeshkumar, NV; Tyner, JW; Yachida, S; Zhong, Y | 1 |
| Chien, W; Ding, L; E-Ling, GL; Hattori, N; Kauffman, M; Koeffler, HP; Lim, SL; Nakamaki, T; Shacham, S; Sudo, M; Sun, H; Sun, Q | 1 |
| Ebi, H; Kita, K; Matsumoto, K; Nanjo, S; Takeuchi, S; Tanimoto, A; Yamada, T; Yano, S | 1 |
| Fang, JM; Lee, YM; Lim, C; Liu, YC; Shie, JJ; Wong, CH | 1 |
| Acquaviva, J; Bates, RC; Jimenez, JP; Proia, DA; Sang, J; Sequeira, M; Smith, DL; Zhang, C | 1 |
| Andou, A; Higashi, R; Okutani, D; Yamadori, I | 1 |
| De Ruysscher, D; Eriksson, J; Even, AJ; Hoebers, FJ; Houben, RM; Lambin, P; Mottaghy, FM; Ollers, MC; Reymen, B; Troost, EG; van Elmpt, W; Windhorst, AD; Zegers, CM | 1 |
| Brown, MP; Singhal, N; Vatandoust, S | 1 |
| Lanuti, M; Lerwill, MF; Moy, B; Rafferty, EA; Specht, MC | 1 |
| Biemans, R; Dubois, LJ; Hart, CP; Lambin, P; Lieuwes, NG; Peeters, SG; Sun, JD; van Elmpt, W; van Stiphout, RG; Windhorst, AD; Yaromina, A; Zegers, CM | 1 |
| Cominetti, D; De Cesare, M; Deraco, M; Doldi, V; Friedlander, S; Gandellini, P; Kauffman, MG; Landesman, Y; Lopergolo, A; Pennati, M; Shacham, S; Zaffaroni, N | 1 |
| Andric, Z; Bondarenko, I; Ceric, T; Ciuleanu, T; Felip, E; Fennell, D; Goss, G; Hirsh, V; Khuri, F; Komov, D; Ramalingam, S; Rosell, R; Salgia, R; Samarzija, M; Schmid-Bindert, G; Shapiro, G; Sheldon, E; Spicer, J; Teofilovici, F; Vukovic, V; Wehler, T; Zaric, B | 1 |
| Brunetti, JC; Chien, D; Kolb, H; Lambin, P; Moon, DH; Srinivas, SM; Subramaniam, RM; Szardenings, K; van Elmpt, W; Waxman, A; Zegers, CM | 1 |
| Asahina, H; Beauchamp, EM; Buczkowski, KA; Hammerman, PS; Li, YY; Meyerson, M; Terai, H; Wong, KK; Xu, C; Zhang, Y | 1 |
| Cao, J; Desilva, H; Fairchild, C; Johnston, K; Kirov, S; Lei, M; Lenhart, R; Peterson, R; Purandare, A; Ross-Macdonald, P; Schweizer, L; Wee, S; Wong, T | 1 |
| Das, M; Dingemans, AC; Even, AJG; Lambin, P; Mottaghy, FM; Oellers, M; Reymen, B; Troost, EGC; van Elmpt, W; Wildberger, JE; Zegers, CML | 1 |
| Bosenberg, MW; Held, MA; Iyidogan, P; Langdon, CG; Levy, F; Mamillapalli, R; Platt, JT; Stern, DF; Theodosakis, N; Vuagniaux, G; Wang, S; Wiedemann, N | 1 |
| Epperly, MW; Gomez-Casal, R; Greenberger, JS; Levina, V; Proia, DA; Wang, H | 1 |
| Alvarez, CE; Clemente-Vicario, F; Kisseberth, WC; London, CA; Lorch, G; Rowell, JL; Roy, S | 1 |
| Cai, H; Huang, X; Huang, Y; Jiang, B; Jiang, J; Shen, H; Sun, Y; Wu, X; Xu, J; Xu, S; Yao, H; Zhang, P | 1 |
| Calvo, F; Chakravarty, P; Del Pozo Martin, Y; Derzsi, S; Hill, CS; Malanchi, I; Ombrato, L; Park, D; Ramachandran, A; Sahai, E; Spencer-Dene, B | 1 |
| Abdul Nazeer, KA; Palakal, M; Pradhan, M; Shabana, KM | 1 |
| Chang, H; Du, S; Liu, H; Liu, Y; Wang, P; Xue, M; Zhang, L | 1 |
| Benner, A; Berthel, A; Brand, K; Buechler, MW; Falk, CS; Grabe, N; Halama, N; Herrmann, T; Jaeger, D; Kahlert, C; Klupp, F; Koch, M; Krauss, J; Kunz, C; Lasitschka, F; Lerchl, T; Luckner-Minden, C; Luecke, S; Schneider, M; Springfeld, C; Suarez-Carmona, M; Suetterlin, T; Ulrich, A; Weitz, J; Zitvogel, L; Zoernig, I | 1 |
| Belosay, A; Churchwell, MI; Doerge, DR; Hartman, JA; Helferich, WG; Iwaniec, UT; Song, H; Turner, RT; Wang, W; Yang, X | 1 |
| Diao, L; Komaki, R; Lin, SH; Liu, H; Potter, A; Proia, DA; Qiao, Y; Tailor, R; Wang, J; Wang, Y; Zhang, J | 1 |
| Bogman, K; Bordogna, W; Cleary, Y; Dall, G; De Petris, L; Guerini, E; Martin-Facklam, M; Morcos, PN; Phipps, A; Viteri, S; Yu, L | 1 |
| Barrero, MJ; Brooks, HB; Campbell, RM; García-Carpizo, V; Graña, O; Han, B; Pisano, DG; Ruiz-Llorente, S; Sarmentero, J; Serrano, M | 1 |
| Gelato, KA; Haendler, B; Klingbeil, O; Lejeune, P; Lesche, R | 1 |
| Alibés, A; Fiorentino, FP; Kato, F; Kohno, T; Perucho, M; Sánchez-Céspedes, M; Yokota, J | 1 |
| Giaccone, G; Subramaniam, DS; Warner, EA | 1 |
| Lee, D; Lee, HE; Lee, SH; Lee, T; Lee, YM; Park, K | 1 |
| Banerjee, T; Heckert, B; Kallu, J; Naz, S; Santra, S; Shelby, T; Sulthana, S; Vuppala, SR; Yambem, O | 1 |
| Endo, T; Hasegawa, K; Higashi, Y; Kamiya, A; Kaneko, J; Kondo, I; Maejima, S; Takatsuno, Y | 1 |
| Geng, Y; Lin, Z; Mei, H; Wang, J; Wang, Y; Wu, G; Yin, Z; Zhang, T | 1 |
| Belli, C; Giovannini, M; Gregorc, V; Villa, E | 1 |
| Narahara, H; Nasu, K; Takai, N; Tsuno, A | 1 |
| Bellone, S; McKenney, JK; Santin, AD; Shah, HR; Stone, PJ | 1 |
| Kulpraneet, M; Panichchob, P; Prayongratana, K; Tantisiriwat, W | 1 |
| Hashida, S; Hirano, Y; Iga, K; Inukai, M; Ito, M; Kanaya, Y; Maruyama, S; Shimo, T; Yokoyama, N | 1 |
| Abreu, P; Cameron, DA; Campos, SM; Guastalla, JP; Subar, M; Winer, EP | 1 |
| de Melo, SJ; do Nascimento, SC; dos Anjos, JV; Neves Filho, RA; Sinou, D; Srivastava, RM | 1 |
| Mazur, L; Mendyk, E; Pachuta-Stec, A; Pitucha, M; Rzaczyńska, Z; Rzymowska, J | 1 |
| Choe, DH; Kang, MS; Kim, CH; Lee, JC; Noh, GY | 1 |
| Caravelli, JF; Dang, C; Dickler, MN; Flombaum, CD; Fornier, M; Geneus, S; Grothusen, J; Hudis, CA; Lake, D; Melisko, ME; Norton, L; Park, JW; Patil, S; Paulson, M; Robson, M; Rugo, HS; Seidman, AD; Theodoulou, M; Traina, TA; Yeh, B | 1 |
| Ballman, KV; Bot, B; Buckner, JC; DeMatteo, RP; Hillman, SL; Mandrekar, SJ; Nelson, H; Perez, EA; Sargent, DJ | 1 |
| Fisher, C; Jones, RL; Judson, IR; Ratnayake, G; Scurr, M; Thway, K | 1 |
| Albertoni, B; Bill, A; Chatterjee, S; Famulok, M; Heukamp, LC; Lang, T; Meffert, L; Schmitz, A; Schreiber, A; Song, JN; Thomas, RK; Thorwirth, F; Ullrich, RT; Verveer, PJ; Walrafen, D; Zimmer, S | 1 |
| Ashton, S; Barry, ST; Blakey, D; Lewis, CE; Murdoch, C; Tazzyman, S; Wood, P | 1 |
| Jin, CH; Kim, DK; Nam, JS; Park, CY; Sheen, YY; Son, JY | 1 |
| Ancochea, J; Casanova, A | 1 |
| Cornish, NE; Hoffman, MA; Simonsen, KA | 1 |
| Elango, S; Hebbar, K; Mayur, YC; Panjamurthy, K; Purohit, MN; Raghavan, SC | 1 |
| Barsoum, J; Borgman, CL; Carey, CD; Carretero, J; Chen, L; Foley, KP; Inoue, T; Jimenez, JP; Li, D; Li, YC; Meyerson, M; Perera, SA; Rodig, SJ; Sang, J; Shapiro, GI; Shimamura, T; Sinha, P; Wong, KK; Ying, W | 1 |
| Bill, A; Famulok, M; Hannam, JS; Heukamp, LC; König, K; Schmitz, A | 1 |
| Riedmann, EM | 1 |
| Cunningham, DE; Dacic, S; Keohavong, P; Land, SR; Rothstein, ME; Siegfried, JM; Stabile, LP | 1 |
| Abe, K; Kondo, T; Miki, Y; Nagasaki, S; Niikawa, H; Sasano, H; Suzuki, S; Verma, MK | 1 |
| Chen, Z; Li, Z; Liao, M; Lu, S; Niu, X; Shen, L; Shen, S; Yu, Y | 1 |
| Acquaviva, J; Friedland, JC; He, S; Proia, DA; Sang, J; Sequeira, M; Smith, DL; Wada, Y; Zhang, C | 1 |
| Ford, SJ; Jansson, PJ; Kalinowski, DS; Kovacevic, Z; Lovejoy, DB; Lui, GY; Obeidy, P; Richardson, DR; Sharp, DM; Tselepis, C | 1 |
| Bradner, JE; Lockwood, WW; Varmus, H; Zejnullahu, K | 1 |
| Hosoya, T; Imai, S; Kuzumaki, N; Morita, H; Nagasawa, A; Narita, M; Okada, Y; Okano, H; Okano, HJ; Suzuki, A; Suzuki, T; Yamamizu, K; Yamashita, JK | 1 |
| Akamatsu, K; Ito, T; Kumar, A; Kumar, D; Kusaka, E; Mishra, BA; Shekar, KP | 1 |
| Zhang, HJ; Zhang, L; Zhang, XT | 1 |
| Digklia, A; Voutsadakis, IA | 1 |
| Enomoto, K; Kinoshita, T; Nishimura, M; Okamura, Y; Oura, S; Sakurai, T; Yokochi, H | 1 |
| Chiles, J; Kohn, EC; Moody, E; Moody, TW; Sieczkiewicz, GJ | 1 |
| Gertler, SZ; Mauriac, L; Osborne, CK; Pippen, JE; Quaresma Albano, J | 1 |
| Casanovas, J; Milla, L; Milla-Santos, A; Pons, M; Portella, J; Puig-Gali, M; Rallo, L; Rodes, E | 1 |
| Konovalova, NP | 1 |
| BISAGNI, E; ENNUYER, A; ROYER, R; ZAJDELA, F | 1 |
| Howell, A; Robertson, JF; Vergote, I | 1 |
| Christopoulos, S; Rivera, JA; Small, D; Trifiro, M | 1 |
| Katsumine, Y; Noda, N; Osawa, I; Uehara, S; Yuasa, H | 1 |
| Hoffman, MA; Khan, A | 1 |
| Dubinett, SM; Fishbein, MC; Garban, HJ; Goodglick, L; Marquez-Garban, DC; Pietras, RJ; Weinberg, OK | 1 |
| Rennie, I; Rundle, P | 1 |
| Giordano, SH; Hortobagyi, GN | 1 |
| Cai, LF; Erdjument-Bromage, H; Kaufman, AJ; Pandolfi, PP; Scaglioni, PP; Singh, B; Tempst, P; Teruya-Feldstein, J; Yung, TM | 1 |
| Attoub, S; Bruyneel, E; Emami, S; Gespach, C; Grijelmo, C; Nguyen, QD; Rivat, C; Rodrigue, CM; Rodrigues, S | 1 |
| Wu, SH; Yeh, SL | 1 |
| Brauner, M; Bréchot, JM; Destable, MD; Duperron, F; Kamboucher, M; Morère, JF | 1 |
| Burnett, AF; Hardman, MP; Roman, JJ; Santin, AD | 1 |
| Pritchard, KI; Seong Ooi, W; Soon Wong, N | 1 |
| Adjei, AA; Bauman, MD; Bernath, AM; Fitch, TR; Graham, DL; Hauge, MD; Hillman, SL; Jett, JR; Johnson, EA; Kugler, JW; Mandrekar, SJ; Marks, RS; Moore, DF; Perez, EA; Soori, GS; Windschitl, HE; Wos, EJ | 1 |
| Alkasi, O; Beckmann, MW; Fasching, P; Jonat, W; Maass, N; Meinhold-Heerlein, I; Zaki, R | 1 |
| Hua, BY; Huan, LC | 1 |
| Day, A; Felder, CC; Freer, R; Holmes, KA; Jacobs, W; Kohn, EC; Liotta, LA | 1 |
| Bai, S; Chun, SB; Chung, KC; Ha, TY; Im, SY; Kang, HS; Kim, JW; Ko, HM; Lee, HB; Lee, HK; Lee, YB; Oh, SJ | 1 |
| Bielenberg, D; Fidler, IJ; Huang, S; Jiang, W; McConkey, DJ; Salas, T; Wang, Y; Xie, K; Xu, L | 1 |
| Shibamoto, Y | 1 |
| Kothari, L; Murugesan, S; Nair, CK; Noronha, OP; Samuel, AM; Shetty, SJ; Srivastava, TS | 1 |
| Buzdar, AU; Giordano, SH; Hortobagyi, GN; Valero, V | 1 |
| Hansen, F; Hansen, HH; Hansen, M; Lund, B | 1 |
| Banham, SW; Cunningham, D; Soukop, M | 1 |
| Arnold, H; Fiebig, HH; Henss, H; Klee, M; Peukert, M; Queisser, W; von Bültzingslöwen, F | 1 |
| Birch, R; Broder, LE; Krauss, S | 1 |
| Vasil'eva, NN | 2 |
| Tudhope, GR | 1 |
7 review(s) available for triazoles and Lung Neoplasms
| Article | Year |
|---|---|
Heat shock protein 90 inhibitors in non-small-cell lung cancer.
Topics: Benzamides; Benzoquinones; Carcinoma, Non-Small-Cell Lung; HSP90 Heat-Shock Proteins; Humans; Isoindoles; Isoxazoles; Lactams, Macrocyclic; Lung Neoplasms; Molecular Targeted Therapy; Resorcinols; Treatment Outcome; Triazoles | 2014 |
Ganetespib for small cell lung cancer.
Topics: Animals; Antineoplastic Agents; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Molecular Weight; Small Cell Lung Carcinoma; Triazoles; Up-Regulation | 2017 |
Acute monoblastic leukemia with t(10;11)(p12;q23) presenting with pulmonary involvement: a case report and literature review.
Topics: Adult; Antibiotics, Antineoplastic; Antifungal Agents; Antimetabolites, Antineoplastic; Aspergillosis, Allergic Bronchopulmonary; Bronchoalveolar Lavage; Caspofungin; Cytarabine; Echinocandins; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Monocytic, Acute; Lipopeptides; Lung Neoplasms; Male; Pyrimidines; Thailand; Triazoles; Voriconazole | 2008 |
[Mechanisms of resistance to crizotinib in patients with transforming EML4-ALK fusion gene].
Topics: Apoptosis; Benzoquinones; Carcinoma, Non-Small-Cell Lung; Crizotinib; Drug Resistance, Neoplasm; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Lung Neoplasms; Mutation; Oncogene Proteins, Fusion; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Triazoles | 2012 |
A review of the efficacy of anastrozole in postmenopausal women with advanced breast cancer with visceral metastases.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials, Phase III as Topic; Female; Humans; Liver Neoplasms; Lung Neoplasms; Neoplasm Metastasis; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles | 2003 |
Hormonal manipulation of benign metastasizing leiomyomas: report of two cases and review of the literature.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Brachial Plexus Neuropathies; Enzyme Inhibitors; Estrogen Receptor Modulators; Female; Gonadotropin-Releasing Hormone; Humans; Leiomyoma; Lung Neoplasms; Magnetic Resonance Imaging; Middle Aged; Neoplasm Invasiveness; Neoplasms; Nitriles; Radiography, Thoracic; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Triazoles; Uterine Neoplasms | 2004 |
[Contribution of radiation biology to the development of radiation therapy].
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Dose Fractionation, Radiation; Humans; Imidazoles; Lung Neoplasms; Neoplasms; Nimorazole; Radiation-Sensitizing Agents; Triazoles | 1999 |
13 trial(s) available for triazoles and Lung Neoplasms
| Article | Year |
|---|---|
Selinexor in combination with carboplatin and paclitaxel in patients with advanced solid tumors: Results of a single-center, multi-arm phase Ib study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Female; Humans; Hydrazines; Lung Neoplasms; Nausea; Neoplasms; Ovarian Neoplasms; Paclitaxel; Thrombocytopenia; Triazoles; Vomiting | 2022 |
Targeted inhibition of the molecular chaperone Hsp90 overcomes ALK inhibitor resistance in non-small cell lung cancer.
Topics: Adult; Anaplastic Lymphoma Kinase; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Crizotinib; Drug Resistance, Neoplasm; Female; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Mice, SCID; Pyrazoles; Pyridines; Receptor Protein-Tyrosine Kinases; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays; Young Adult | 2013 |
A multicenter phase II study of ganetespib monotherapy in patients with genotypically defined advanced non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Anaplastic Lymphoma Kinase; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Female; Gene Rearrangement; Genotype; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Neoplasm Staging; Receptor Protein-Tyrosine Kinases; Treatment Outcome; Triazoles | 2013 |
Pilot randomised study of early intervention based on tumour markers in the follow-up of patients with primary breast cancer.
Topics: Adult; Aged; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoembryonic Antigen; Early Detection of Cancer; Female; Follow-Up Studies; Goserelin; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Mucin-1; Nitriles; Pilot Projects; Single-Blind Method; Tamoxifen; Treatment Outcome; Triazoles | 2014 |
Phase II study evaluating efficacy and safety of everolimus with letrozole for management of advanced (unresectable or metastatic) non-small cell lung cancer after failure of platinum-based treatment: a preliminary analysis of toxicity.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Carcinoma, Non-Small-Cell Lung; Everolimus; Female; Humans; Letrozole; Lung Diseases; Lung Neoplasms; Male; Middle Aged; Nitriles; Organoplatinum Compounds; Sirolimus; Smoking; Triazoles | 2015 |
A randomized phase II study of ganetespib, a heat shock protein 90 inhibitor, in combination with docetaxel in second-line therapy of advanced non-small cell lung cancer (GALAXY-1).
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Docetaxel; Female; HSP90 Heat-Shock Proteins; Humans; L-Lactate Dehydrogenase; Lung Neoplasms; Male; Middle Aged; Proportional Hazards Models; Proto-Oncogene Proteins p21(ras); Taxoids; Treatment Outcome; Triazoles | 2015 |
Repeatability of hypoxia PET imaging using [¹⁸F]HX4 in lung and head and neck cancer patients: a prospective multicenter trial.
Topics: Aged; Biological Transport; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Nitroimidazoles; Positron-Emission Tomography; Prospective Studies; Reproducibility of Results; Triazoles | 2015 |
Multiparametric imaging of patient and tumour heterogeneity in non-small-cell lung cancer: quantification of tumour hypoxia, metabolism and perfusion.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Multimodal Imaging; Nitroimidazoles; Oxygen; Oxygen Consumption; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed; Triazoles | 2016 |
Clinical Drug-Drug Interactions Through Cytochrome P450 3A (CYP3A) for the Selective ALK Inhibitor Alectinib.
Topics: Adult; Anaplastic Lymphoma Kinase; Carbazoles; Carcinoma, Non-Small-Cell Lung; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Male; Midazolam; Middle Aged; Piperidines; Receptor Protein-Tyrosine Kinases; Rifampin; Treatment Outcome; Triazoles; Young Adult | 2017 |
A comparative study of exemestane versus anastrozole in patients with postmenopausal breast cancer with visceral metastases.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Brain Neoplasms; Breast Neoplasms; Female; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Nitriles; Pilot Projects; Postmenopause; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome; Triazoles | 2009 |
Fulvestrant (Faslodex) versus anastrozole for the second-line treatment of advanced breast cancer in subgroups of postmenopausal women with visceral and non-visceral metastases: combined results from two multicentre trials.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Double-Blind Method; Estradiol; Female; Fulvestrant; Humans; Liver Neoplasms; Lung Neoplasms; Nitriles; Postmenopause; Retrospective Studies; Treatment Outcome; Triazoles | 2003 |
Anastrozole versus tamoxifen as first-line therapy in postmenopausal patients with hormone-dependent advanced breast cancer: a prospective, randomized, phase III study.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Neoplasms; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Lung Neoplasms; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Prospective Studies; Remission Induction; Survival Analysis; Tamoxifen; Triazoles | 2003 |
Phase III randomized, double-blind study of maintenance CAI or placebo in patients with advanced non-small cell lung cancer (NSCLC) after completion of initial therapy (NCCTG 97-24-51).
Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Placebos; Quality of Life; Triazoles | 2008 |
152 other study(ies) available for triazoles and Lung Neoplasms
| Article | Year |
|---|---|
Epigenetic readers and lung cancer: the rs2427964C>T variant of the bromodomain and extraterminal domain gene BRD3 is associated with poorer survival outcome in NSCLC.
Topics: Azepines; Carcinoma, Non-Small-Cell Lung; Epigenesis, Genetic; Humans; Lung Neoplasms; Transcription Factors; Triazoles | 2022 |
Anti-Lung Cancer Activities of 1,2,3-Triazole Curcumin Derivatives via Regulation of the MAPK/NF-κB/STAT3 Signaling Pathways.
Topics: Animals; Antineoplastic Agents; Antioxidants; Biphenyl Compounds; Cell Proliferation; Cell Survival; Cells, Cultured; Curcumin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinases; Molecular Structure; Neoplasms, Experimental; NF-kappa B; Picrates; STAT3 Transcription Factor; Structure-Activity Relationship; Triazoles; Zebrafish | 2022 |
Click ferrocenyl-erlotinib conjugates active against erlotinib-resistant non-small cell lung cancer cells in vitro.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; ErbB Receptors; Erlotinib Hydrochloride; Humans; Iron Compounds; Lung Neoplasms; Molecular Structure; Protein Kinase Inhibitors; Structure-Activity Relationship; Triazoles | 2022 |
Use of Modeling and Simulation to Predict the Influence of Triazole Antifungal Agents on the Pharmacokinetics of Crizotinib.
Topics: Antifungal Agents; Carcinoma, Non-Small-Cell Lung; Crizotinib; Fluconazole; Humans; Itraconazole; Lung Neoplasms; Triazoles; Voriconazole | 2022 |
Co-treatment with vactosertib, a novel, orally bioavailable activin receptor-like kinase 5 inhibitor, suppresses radiotherapy-induced epithelial-to-mesenchymal transition, cancer cell stemness, and lung metastasis of breast cancer.
Topics: Aniline Compounds; Animals; Breast Neoplasms; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Female; Humans; Lung Neoplasms; Mice; Protein Kinase Inhibitors; Receptor, Transforming Growth Factor-beta Type I; Transforming Growth Factor beta; Triazoles | 2022 |
Mubritinib enhanced the inhibiting function of cisplatin in lung cancer by interfering with mitochondrial function.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Humans; Lung Neoplasms; Mice; Mitochondria; Oxazoles; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Triazoles | 2022 |
Electronic Coupling in 1,2,3-Triazole Bridged Ferrocenes and Its Impact on Reactive Oxygen Species Generation and Deleterious Activity in Cancer Cells.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Electronics; Humans; Lung Neoplasms; Metallocenes; Reactive Oxygen Species; Triazoles | 2022 |
Combined anticancer therapy with imidazoacridinone analogue C-1305 and paclitaxel in human lung and colon cancer xenografts-Modulation of tumour angiogenesis.
Topics: Acridines; Apoptosis; Colonic Neoplasms; Heterografts; Humans; Lung; Lung Neoplasms; Paclitaxel; Triazoles | 2022 |
Inhibition of Mtorc1/2 and DNA-PK via CC-115 Synergizes with Carboplatin and Paclitaxel in Lung Squamous Cell Carcinoma.
Topics: Animals; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; DNA; Humans; Lung; Lung Neoplasms; Mechanistic Target of Rapamycin Complex 1; Mice; Paclitaxel; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyrazines; TOR Serine-Threonine Kinases; Triazoles | 2022 |
AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity.
Topics: A549 Cells; Animals; Antibiotics, Antineoplastic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; DNA-Activated Protein Kinase; Doxorubicin; Drug Synergism; Genomic Instability; Humans; Lung Neoplasms; Mice; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Glycols; Protein Kinase Inhibitors; Purines; Pyrans; Radiation Tolerance; Radiotherapy; Triazoles; Xenograft Model Antitumor Assays | 2019 |
α7-Nicotinic acetylcholine receptor antagonist QND7 suppresses non-small cell lung cancer cell proliferation and migration via inhibition of Akt/mTOR signaling.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Inhibitory Concentration 50; Lung Neoplasms; Proto-Oncogene Proteins c-akt; Quinuclidines; Signal Transduction; TOR Serine-Threonine Kinases; Triazoles | 2020 |
Primary cutaneous mucormycosis of the abdomen at the site of repeated insulin injections.
Topics: Abdomen; Aged; Anti-Bacterial Agents; Antifungal Agents; Dermatomycoses; Diabetes Mellitus, Type 2; Female; Humans; Immunocompromised Host; Injection Site Reaction; Injections, Subcutaneous; Insulin; Lung Neoplasms; Mucormycosis; Necrosis; Nitriles; Pyridines; Triazoles; Vancomycin | 2020 |
BRD4 Levels Determine the Response of Human Lung Cancer Cells to BET Degraders That Potently Induce Apoptosis through Suppression of Mcl-1.
Topics: Animals; Apoptosis; Azepines; Cell Cycle Proteins; Cell Line, Tumor; Humans; Lung Neoplasms; Mice; Myeloid Cell Leukemia Sequence 1 Protein; Proteins; Thalidomide; Transcription Factors; Triazoles; Xenograft Model Antitumor Assays | 2020 |
The IAP Antagonist SM-164 Eliminates Triple-Negative Breast Cancer Metastasis to Bone and Lung in Mice.
Topics: Animals; Apoptosis; Bone Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Doxorubicin; Female; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Mice; Mice, Nude; RANK Ligand; Triazoles; Triple Negative Breast Neoplasms | 2020 |
Dual Inhibition of MEK and AXL Targets Tumor Cell Heterogeneity and Prevents Resistant Outgrowth Mediated by the Epithelial-to-Mesenchymal Transition in NSCLC.
Topics: A549 Cells; Animals; Antineoplastic Combined Chemotherapy Protocols; Axl Receptor Tyrosine Kinase; Benzimidazoles; Benzocycloheptenes; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; Mice, Inbred Strains; Mitogen-Activated Protein Kinase Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Triazoles; Xenograft Model Antitumor Assays | 2021 |
XPO1 inhibition synergizes with PARP1 inhibition in small cell lung cancer by targeting nuclear transport of FOXO3a.
Topics: Active Transport, Cell Nucleus; Animals; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; Cytoplasm; Drug Synergism; Exportin 1 Protein; Female; Forkhead Box Protein O3; Gene Expression Regulation, Neoplastic; Humans; Hydrazines; Karyopherins; Lung Neoplasms; Mice; Phthalazines; Receptors, Cytoplasmic and Nuclear; Small Cell Lung Carcinoma; Triazoles; Xenograft Model Antitumor Assays | 2021 |
BET inhibitors combined with chemotherapy synergistically inhibit the growth of NSCLC cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azepines; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Synergism; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Heterocyclic Compounds, 4 or More Rings; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Paclitaxel; Prognosis; Signal Transduction; Transcription Factors; Triazoles | 2021 |
Therapeutic Efficacy of Lactonic Sophorolipids: Nanoceria-Assisted Combination Therapy of NSCLC using HDAC and Hsp90 Inhibitors.
Topics: A549 Cells; Animals; Antineoplastic Agents; Antioxidants; Carcinoma, Non-Small-Cell Lung; Cerium; CHO Cells; Combined Modality Therapy; Cricetinae; Cricetulus; Glycolipids; Histone Deacetylase Inhibitors; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Triazoles | 2021 |
Synthesis of alkynylated 1,2,4-oxadiazole/1,2,3-1H-triazole glycoconjugates: Discovering new compounds for use in chemotherapy against lung carcinoma and Mycobacterium tuberculosis.
Topics: Alkynes; Animals; Antineoplastic Agents; Antitubercular Agents; Carcinoma, Squamous Cell; Cell Line; Cell Proliferation; Cell Survival; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Discovery; Glycoconjugates; Humans; Lung Neoplasms; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Structure-Activity Relationship; Triazoles | 2021 |
BRD4 inhibition promotes TRAIL-induced apoptosis by suppressing the transcriptional activity of NF-κB in NSCLC.
Topics: A549 Cells; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azepines; Carcinoma, Non-Small-Cell Lung; Cell Cycle Proteins; Fas-Associated Death Domain Protein; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Lung Neoplasms; NF-kappa B; Recombinant Proteins; TNF-Related Apoptosis-Inducing Ligand; Transcription Factors; Transcriptional Activation; Triazoles | 2021 |
Carboxyamidotriazole Synergizes with Sorafenib to Combat Non-Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Lewis Lung; Carcinoma, Non-Small-Cell Lung; Dose-Response Relationship, Drug; Drug Synergism; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Nanog Homeobox Protein; Niacinamide; Phenylurea Compounds; Sorafenib; Triazoles; Xenograft Model Antitumor Assays | 2017 |
Biology and evolution of poorly differentiated neuroendocrine tumors.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Azepines; Benzodiazepines; Carcinogenesis; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Cell Differentiation; Cell Lineage; Cell Plasticity; Colonic Neoplasms; Disease Progression; Epigenesis, Genetic; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Molecular Targeted Therapy; Neoplasms, Glandular and Epithelial; Neuroendocrine Tumors; Ovarian Neoplasms; Prostatic Neoplasms; Proto-Oncogene Proteins c-met; Proto-Oncogene Proteins c-myc; Pyrimidines; Retinoblastoma Binding Proteins; Triazoles; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms | 2017 |
JQ1, a BET Inhibitor, Synergizes with Cisplatin and Induces Apoptosis in Highly Chemoresistant Malignant Pleural Mesothelioma Cells.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Azepines; beta-Galactosidase; Cell Cycle Checkpoints; Cell Cycle Proteins; Cellular Senescence; Cisplatin; DNA Breaks; Drug Resistance, Neoplasm; Drug Synergism; Drug Therapy, Combination; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Nuclear Proteins; Pleural Neoplasms; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Transcription Factors; Transcription, Genetic; Triazoles | 2018 |
Ferrocene-cinchona hybrids with triazolyl-chalcone linkers act as pro-oxidants and sensitize human cancer cell lines to paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Autophagy; Chalcones; Cinchona; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Ferrous Compounds; Humans; Lung Neoplasms; Metallocenes; Oxidants; Paclitaxel; Reactive Oxygen Species; Triazoles; Tumor Cells, Cultured | 2017 |
Allergic bronchopulmonary mycosis presenting as a new lung mass.
Topics: Aged; Anti-Inflammatory Agents; Antifungal Agents; Diagnosis, Differential; Humans; Invasive Pulmonary Aspergillosis; Lung Diseases, Fungal; Lung Neoplasms; Male; Prednisone; Tomography, X-Ray Computed; Triazoles | 2017 |
Design, synthesis and biological evaluation of novel benzimidazole amidines as potent multi-target inhibitors for the treatment of non-small cell lung cancer.
Topics: Amidines; Antineoplastic Agents; Apoptosis; Benzimidazoles; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cells, Cultured; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Protein Kinases; Structure-Activity Relationship; Triazoles | 2018 |
Non-linear conversion of HX4 uptake for automatic segmentation of hypoxic volumes and dose prescription.
Topics: Carcinoma, Non-Small-Cell Lung; Fluorine Radioisotopes; Humans; Imidazoles; Lung Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy Planning, Computer-Assisted; Triazoles; Tumor Hypoxia | 2018 |
A triazole-conjugated benzoxazone induces reactive oxygen species and promotes autophagic apoptosis in human lung cancer cells.
Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Benzoxazines; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Cycle; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 2-Ring; Humans; Injections, Subcutaneous; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubule-Associated Proteins; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Signal Transduction; Triazoles; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2018 |
Small molecule purine and pseudopurine derivatives: synthesis, cytostatic evaluations and investigation of growth inhibitory effect in non-small cell lung cancer A549.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cells, Cultured; Cytostatic Agents; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Models, Molecular; Molecular Structure; Purines; Small Molecule Libraries; Structure-Activity Relationship; Triazoles | 2018 |
HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cellular Senescence; Cisplatin; Drug Resistance, Neoplasm; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Male; Mesothelioma; Mesothelioma, Malignant; Mice; Mice, Inbred NOD; Mice, SCID; Pemetrexed; Secretory Pathway; Triazoles | 2018 |
Targeting BRD4 proteins suppresses the growth of NSCLC through downregulation of eIF4E expression.
Topics: A549 Cells; Animals; Azepines; Carcinoma, Non-Small-Cell Lung; Cell Cycle Proteins; Cell Line, Tumor; Disease Models, Animal; Down-Regulation; Eukaryotic Initiation Factor-4E; Heterocyclic Compounds, 4 or More Rings; Humans; Lung Neoplasms; Mice; Mice, Nude; Molecular Targeted Therapy; Nuclear Proteins; Random Allocation; Transcription Factors; Transfection; Triazoles; Xenograft Model Antitumor Assays | 2018 |
HSP90 inhibition targets autophagy and induces a CASP9-dependent resistance mechanism in NSCLC.
Topics: Autophagy; Autophagy-Related Protein 7; Carcinoma, Non-Small-Cell Lung; Caspase 9; Cell Line, Tumor; Cytoprotection; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Stability; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Mutation; Protein Domains; Triazoles; Up-Regulation | 2018 |
New 1,2,4-triazole-Chalcone hybrids induce Caspase-3 dependent apoptosis in A549 human lung adenocarcinoma cells.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Caspase 3; Chalcones; Enzyme Activation; Humans; Lung Neoplasms; Triazoles | 2018 |
NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azepines; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Histone Deacetylase 6; Humans; Hydroxamic Acids; Killer Cells, Natural; Lung Neoplasms; Mice; Neoplasm Recurrence, Local; Proteins; Pyrimidines; RNA, Small Interfering; Small Cell Lung Carcinoma; Synthetic Lethal Mutations; Treatment Outcome; Triazoles; Xenograft Model Antitumor Assays | 2018 |
Pulmonary blastomycosis presenting as primary lung cancer.
Topics: Antifungal Agents; Blastomyces; Blastomycosis; Diagnosis, Differential; DNA, Fungal; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Positron Emission Tomography Computed Tomography; Tomography, X-Ray Computed; Triazoles | 2018 |
JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states.
Topics: Acetylation; Animals; Azepines; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chromatin; Gene Expression Regulation, Neoplastic; Histones; Humans; Lung Neoplasms; Mice; Models, Molecular; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Transcription Factors; Transcription Initiation Site; Triazoles | 2018 |
BET Bromodomain Inhibition Cooperates with PD-1 Blockade to Facilitate Antitumor Response in
Topics: Adoptive Transfer; Animals; Azepines; Carcinoma, Non-Small-Cell Lung; Cytokines; Lung Neoplasms; Mice, Nude; Mice, Transgenic; Mutation; Nuclear Proteins; Programmed Cell Death 1 Receptor; Proto-Oncogene Proteins p21(ras); T-Lymphocytes; Triazoles; Tumor Suppressor Protein p53 | 2018 |
Axl kinase drives immune checkpoint and chemokine signalling pathways in lung adenocarcinomas.
Topics: Adenocarcinoma of Lung; Antineoplastic Agents; Axl Receptor Tyrosine Kinase; B7-H1 Antigen; Benzocycloheptenes; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cohort Studies; Disease Progression; Epithelial-Mesenchymal Transition; ErbB Receptors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Prognosis; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptors, CXCR6; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Triazoles | 2019 |
Nanomedicine-Assisted Combination Therapy of NSCLC: New Platinum-Based Anticancer Drug Synergizes the Therapeutic Efficacy of Ganetespib.
Topics: A549 Cells; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; CHO Cells; Cricetulus; Humans; Lung Neoplasms; Magnetic Fields; Magnetite Nanoparticles; Nanomedicine; Organoplatinum Compounds; Proto-Oncogene Proteins p21(ras); Triazoles | 2019 |
Ganetespib in Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor-resistant Non-small Cell Lung Cancer.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Female; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Mutation; Protein Kinase Inhibitors; Proto-Oncogene Mas; Signal Transduction; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays | 2019 |
XPO1 inhibitor KPT-330 synergizes with Bcl-xL inhibitor to induce cancer cell apoptosis by perturbing rRNA processing and Mcl-1 protein synthesis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzothiazoles; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Down-Regulation; Drug Synergism; Eukaryotic Initiation Factor-4F; Exportin 1 Protein; Humans; Hydrazines; Isoquinolines; Karyopherins; Lung Neoplasms; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred NOD; Mice, SCID; Myeloid Cell Leukemia Sequence 1 Protein; Receptors, Cytoplasmic and Nuclear; RNA, Ribosomal; Triazoles | 2019 |
Inhibition of BRD4 suppresses the malignancy of breast cancer cells via regulation of Snail.
Topics: Animals; Antineoplastic Agents; Azepines; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice, Nude; Mice, SCID; Middle Aged; Protein Kinase C; Protein Stability; Snail Family Transcription Factors; Transcription Factors; Transcription, Genetic; Triazoles; Zinc Finger Protein GLI1 | 2020 |
Genomic signatures defining responsiveness to allopurinol and combination therapy for lung cancer identified by systems therapeutics analyses.
Topics: Allopurinol; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genomics; Humans; Janus Kinase 2; Lung Neoplasms; Mice, Nude; Phenotype; Protein Kinase Inhibitors; Pyridines; Systems Analysis; Triazoles; Xenograft Model Antitumor Assays | 2019 |
Bromodomain and extraterminal domain inhibition synergizes with WEE1-inhibitor AZD1775 effect by impairing nonhomologous end joining and enhancing DNA damage in nonsmall cell lung cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azepines; Carcinoma, Non-Small-Cell Lung; Cell Cycle Proteins; Cell Line, Tumor; DNA Breaks, Double-Stranded; DNA End-Joining Repair; DNA-Binding Proteins; Drug Synergism; Female; Gene Knockdown Techniques; Heterocyclic Compounds, 2-Ring; Humans; Lung Neoplasms; Mice; Piperazines; Protein-Tyrosine Kinases; Pyrazoles; Pyridazines; Pyrimidinones; Transcription Factors; Triazoles; Xenograft Model Antitumor Assays | 2020 |
The triazole linked galactose substituted dicyano compound can induce autophagy in NSCLC cell lines.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroquine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Galactose; Humans; Inhibitory Concentration 50; Lung Neoplasms; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Naphthyridines; Signal Transduction; TOR Serine-Threonine Kinases; Triazoles | 2019 |
Synthesis, activity evaluation, and pro-apoptotic properties of novel 1,2,4-triazol-3-amine derivatives as potent anti-lung cancer agents.
Topics: Amines; Antineoplastic Agents; Apoptosis; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Proton Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Triazoles | 2019 |
Triazole-Pyridine Dicarbonitrile Targets Phosphodiesterase 4 to Induce Cytotoxicity in Lung Carcinoma Cells.
Topics: A549 Cells; Antineoplastic Agents; Cell Proliferation; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Molecular Structure; Nitriles; Phosphodiesterase 4 Inhibitors; Pyridines; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured | 2019 |
Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells.
Topics: Animals; Azepines; Basic Helix-Loop-Helix Transcription Factors; Biomarkers, Tumor; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Insulin-Like Growth Factor Binding Protein 5; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasms, Experimental; Neuroendocrine Tumors; Octamer Transcription Factors; Proteomics; Pyrazoles; Receptor, IGF Type 1; Signal Transduction; Small Cell Lung Carcinoma; Transcription Factors; Triazines; Triazoles | 2019 |
Hypofractionated stereotactic radiotherapy with the hypoxic sensitizer AK-2123 (sanazole) for reirradiation of brain metastases: a preliminary feasibility report.
Topics: Administration, Oral; Adult; Aged; Brain Neoplasms; Breast Neoplasms; Combined Modality Therapy; Cranial Irradiation; Dose Fractionation, Radiation; Feasibility Studies; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prognosis; Radiation-Sensitizing Agents; Radiosurgery; Triazoles | 2013 |
Inhibition of CK2 enhances UV-triggered apoptotic cell death in lung cancer cell lines.
Topics: Apoptosis; Casein Kinase II; Caspase 3; Cell Line, Tumor; Cell Survival; Cytochromes c; Humans; Lung Neoplasms; Nuclear Proteins; Poly(ADP-ribose) Polymerases; Promyelocytic Leukemia Protein; RNA Interference; RNA, Small Interfering; Transcription Factors; Triazoles; Tumor Suppressor Proteins; Ultraviolet Rays | 2013 |
A 76-year-old man with a right lung adenocarcinoma and invasive Aspergillosis.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Antifungal Agents; Aspergillus fumigatus; Histocytochemistry; Humans; Invasive Pulmonary Aspergillosis; Lung; Lung Neoplasms; Male; Microscopy; Molecular Diagnostic Techniques; Polymerase Chain Reaction; Positron-Emission Tomography; Pyrimidines; Triazoles; Voriconazole | 2013 |
Strengthening context-dependent anticancer effects on non-small cell lung carcinoma by inhibition of both MET and EGFR.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Humans; Lung Neoplasms; Mice; Molecular Targeted Therapy; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridazines; Quinazolines; Signal Transduction; Small Cell Lung Carcinoma; Triazoles; Xenograft Model Antitumor Assays | 2013 |
Design, synthesis, and evaluation of novel VEGFR2 kinase inhibitors: discovery of [1,2,4]triazolo[1,5-a]pyridine derivatives with slow dissociation kinetics.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Human Umbilical Vein Endothelial Cells; Humans; Kinetics; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Prostatic Neoplasms; Protein Kinase Inhibitors; Pyridines; Random Allocation; Structure-Activity Relationship; Triazoles; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2013 |
Ganetespib AIDS lung cancer survival.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Neoplasm Staging; Randomized Controlled Trials as Topic; Survival Analysis; Taxoids; Triazoles; Xenograft Model Antitumor Assays | 2013 |
Antagonism of adenosine A2A receptor expressed by lung adenocarcinoma tumor cells and cancer associated fibroblasts inhibits their growth.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adenosine A2 Receptor Antagonists; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Fibroblasts; Heterografts; Humans; Lung Neoplasms; Mice, Nude; Pyrimidines; Receptor, Adenosine A2A; Triazines; Triazoles | 2013 |
Hypoxia imaging with [¹⁸F]HX4 PET in NSCLC patients: defining optimal imaging parameters.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Female; Fluorine Radioisotopes; Humans; Imidazoles; Lung Neoplasms; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Triazoles | 2013 |
Efficacy of BET bromodomain inhibition in Kras-mutant non-small cell lung cancer.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Azepines; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Lung Neoplasms; Mice; Mice, Knockout; Nuclear Proteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins p21(ras); RNA Interference; RNA, Small Interfering; Signal Transduction; Transcription Factors; Triazoles | 2013 |
HSP-90 inhibitor ganetespib is synergistic with doxorubicin in small cell lung cancer.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Synergism; G2 Phase Cell Cycle Checkpoints; HSP90 Heat-Shock Proteins; Humans; Inhibitory Concentration 50; Lung Neoplasms; Mice; Mice, Nude; Small Cell Lung Carcinoma; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
Preclinical activity profile and therapeutic efficacy of the HSP90 inhibitor ganetespib in triple-negative breast cancer.
Topics: Animals; Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Disease Models, Animal; DNA Damage; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Synergism; Female; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Mice; Mitosis; Neoplasm Metastasis; Neoplasm Staging; Positron-Emission Tomography; Tomography, X-Ray Computed; Triazoles; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2014 |
Targeting small cell lung cancer harboring PIK3CA mutation with a selective oral PI3K inhibitor PF-4989216.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Class I Phosphatidylinositol 3-Kinases; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Humans; Immunoblotting; Lung Neoplasms; Mice; Mice, SCID; Mutation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Small Cell Lung Carcinoma; Thiophenes; Triazoles; Xenograft Model Antitumor Assays | 2014 |
American Society of Clinical Oncology Annual Meeting 2013.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Docetaxel; Erlotinib Hydrochloride; Female; Humans; Imidazoles; Indoles; Lung Neoplasms; Male; Medical Oncology; Multicenter Studies as Topic; Oximes; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Quinazolines; Randomized Controlled Trials as Topic; Small Cell Lung Carcinoma; Societies, Medical; Sulfones; Sunitinib; Taxoids; Treatment Outcome; Triazoles; United States | 2013 |
[Long-term results of personalized treatment in 72 breast cancer patients who failed chemotherapy].
Topics: Adult; Aged; Aromatase Inhibitors; Bone Density Conservation Agents; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Diphosphonates; Drugs, Chinese Herbal; Female; Follow-Up Studies; Humans; Imidazoles; Letrozole; Lung Neoplasms; Medicine, Chinese Traditional; Middle Aged; Neoplasm Staging; Nitriles; Radiotherapy, Adjuvant; Radiotherapy, Conformal; Remission Induction; Retrospective Studies; Survival Rate; Treatment Failure; Triazoles; Zoledronic Acid | 2013 |
mTOR inhibition potentiates HSP90 inhibitor activity via cessation of HSP synthesis.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Female; Heat-Shock Response; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Male; Mice; Mice, SCID; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Random Allocation; Signal Transduction; TOR Serine-Threonine Kinases; Triazoles; Up-Regulation; Xenograft Model Antitumor Assays | 2014 |
Antitumor effects of a novel chromosome region maintenance 1 (CRM1) inhibitor on non-small cell lung cancer cells in vitro and in mouse tumor xenografts.
Topics: Acrylates; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Enzyme Activation; Exportin 1 Protein; Humans; Karyopherins; Lung Neoplasms; Mice, Inbred NOD; Mice, SCID; Receptors, Cytoplasmic and Nuclear; Triazoles; Xenograft Model Antitumor Assays | 2014 |
Hormone dependency in metastatic low-grade leiomyosarcoma following uterine smooth muscle tumour of uncertain malignant potential.
Topics: Adult; Aromatase Inhibitors; Estrogen Replacement Therapy; Estrogens; Female; Humans; Hysterectomy; Leiomyosarcoma; Letrozole; Lung Neoplasms; Menopause; Neoplasms, Hormone-Dependent; Nitriles; Ovariectomy; Pleural Neoplasms; Radiography; Retroperitoneal Neoplasms; Salpingectomy; Triazoles; Uterine Neoplasms | 2014 |
EW-7197, a novel ALK-5 kinase inhibitor, potently inhibits breast to lung metastasis.
Topics: Aniline Compounds; Animals; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Random Allocation; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Triazoles; Xenograft Model Antitumor Assays | 2014 |
Heterogeneity of pancreatic cancer metastases in a single patient revealed by quantitative proteomics.
Topics: Animals; Antineoplastic Agents; Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Cells, Cultured; Humans; Liver Neoplasms; Lung Neoplasms; Mass Spectrometry; Mice; Molecular Targeted Therapy; Pancreatic Neoplasms; Peritoneal Neoplasms; Precision Medicine; Protein Kinase Inhibitors; Proteomics; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Signal Transduction; Triazoles; Xenograft Model Antitumor Assays | 2014 |
KPT-330 has antitumour activity against non-small cell lung cancer.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Growth Processes; Cell Line, Tumor; Cisplatin; Exportin 1 Protein; G1 Phase; Genes, p53; Humans; Hydrazines; Karyopherins; Lung Neoplasms; Male; Mice; Mice, Inbred NOD; Mice, SCID; Mutation; Receptors, Cytoplasmic and Nuclear; Triazoles; Xenograft Model Antitumor Assays | 2014 |
Receptor ligand-triggered resistance to alectinib and its circumvention by Hsp90 inhibition in EML4-ALK lung cancer cells.
Topics: Benzoquinones; Blotting, Western; Carbazoles; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Epidermal Growth Factor; ErbB Receptors; Hepatocyte Growth Factor; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Ligands; Lung Neoplasms; Mutation; Oncogene Proteins, Fusion; Phosphorylation; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Transforming Growth Factor alpha; Triazoles | 2014 |
An azido-BODIPY probe for glycosylation: initiation of strong fluorescence upon triazole formation.
Topics: Azides; Boron Compounds; Cell Line, Tumor; Copper; Cyclization; Fluorescent Dyes; Glycoproteins; Glycosylation; Humans; Lung Neoplasms; Triazoles | 2014 |
The HSP90 inhibitor ganetespib potentiates the antitumor activity of EGFR tyrosine kinase inhibition in mutant and wild-type non-small cell lung cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Female; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Mice, SCID; Mutation; Protein Kinase Inhibitors; Signal Transduction; Time Factors; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
[Pulmonary metastasis from breast cancer 38 years after mastectomy; report of a case].
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Lung Neoplasms; Mastectomy; Nitriles; Time Factors; Tomography, X-Ray Computed; Triazoles | 2014 |
In vivo quantification of hypoxic and metabolic status of NSCLC tumors using [18F]HX4 and [18F]FDG-PET/CT imaging.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Female; Fluorodeoxyglucose F18; Humans; Hypoxia; Image Interpretation, Computer-Assisted; Image Processing, Computer-Assisted; Imidazoles; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed; Triazoles | 2014 |
Case records of the Massachusetts General Hospital. Case 1-2015. A 66-year-old woman with metastatic breast cancer after endocrine therapy.
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Class I Phosphatidylinositol 3-Kinases; Diagnosis, Differential; Female; Humans; Lung Neoplasms; Lymph Nodes; Magnetic Resonance Imaging; Mastectomy, Segmental; Mutation; Nitriles; Phosphatidylinositol 3-Kinases; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Triazoles | 2015 |
TH-302 in Combination with Radiotherapy Enhances the Therapeutic Outcome and Is Associated with Pretreatment [18F]HX4 Hypoxia PET Imaging.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Chemoradiotherapy; Imidazoles; Lung Neoplasms; Nitroimidazoles; Phosphoramide Mustards; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Treatment Outcome; Triazoles; Xenograft Model Antitumor Assays | 2015 |
Anti-tumor activity of selective inhibitors of XPO1/CRM1-mediated nuclear export in diffuse malignant peritoneal mesothelioma: the role of survivin.
Topics: Acrylamides; Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Exportin 1 Protein; G1 Phase Cell Cycle Checkpoints; Humans; Hydrazines; Inhibitor of Apoptosis Proteins; Karyopherins; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Mice; Mice, SCID; Neoplasm Proteins; Oxadiazoles; Peritoneal Neoplasms; Real-Time Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear; Survivin; Thiazoles; Triazoles; Tumor Suppressor Protein p53 | 2015 |
NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Azepines; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dasatinib; Discoidin Domain Receptors; Humans; Inhibitory Concentration 50; Lung Neoplasms; Mice, Nude; Mutation, Missense; N-Myc Proto-Oncogene Protein; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptors, Mitogen; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression.
Topics: Antineoplastic Agents; Azepines; Basic Helix-Loop-Helix Transcription Factors; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enhancer Elements, Genetic; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Lung Neoplasms; Nuclear Proteins; Protein Binding; Small Cell Lung Carcinoma; Transcription Factors; Transcriptome; Triazoles | 2015 |
SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Azepines; Azocines; Benzhydryl Compounds; Camptothecin; Cell Line, Tumor; Cell Proliferation; Docetaxel; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Irinotecan; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Paclitaxel; Signal Transduction; Taxoids; Time Factors; Topoisomerase Inhibitors; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Radioresistant human lung adenocarcinoma cells that survived multiple fractions of ionizing radiation are sensitive to HSP90 inhibition.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Phenotype; Radiation Tolerance; Radiation-Sensitizing Agents; Signal Transduction; Time Factors; Triazoles | 2015 |
Human Genetic Relevance and Potent Antitumor Activity of Heat Shock Protein 90 Inhibition in Canine Lung Adenocarcinoma Cell Lines.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Comparative Genomic Hybridization; Dogs; Dose-Response Relationship, Drug; HSP90 Heat-Shock Proteins; Indoles; Lung Neoplasms; Time Factors; Triazoles | 2015 |
Discovery of novel hybrids of diaryl-1,2,4-triazoles and caffeic acid as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase for cancer therapy.
Topics: Antineoplastic Agents; Apoptosis; Arachidonate 5-Lipoxygenase; Caffeic Acids; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Lipoxygenase Inhibitors; Lung Neoplasms; Molecular Structure; Structure-Activity Relationship; Triazoles | 2016 |
Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization.
Topics: Animals; Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Breast Neoplasms; CD24 Antigen; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Homeodomain Proteins; Humans; Lung Neoplasms; Mice; Mice, Nude; Mice, Transgenic; Neoplasm Metastasis; Neoplastic Stem Cells; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; RNA Interference; Signal Transduction; Smad Proteins; Thrombospondins; Transforming Growth Factor beta; Transplantation, Heterologous; Triazoles | 2015 |
A computational method for drug repositioning using publicly available gene expression data.
Topics: Antineoplastic Agents; Breast Neoplasms; Computational Biology; Databases, Genetic; Drug Repositioning; Female; Gene Expression Regulation, Neoplastic; Hepatitis C; Humans; Letrozole; Lung Neoplasms; Nitriles; Triazoles | 2015 |
Synergistic action of master transcription factors controls epithelial-to-mesenchymal transition.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Azepines; Cell Cycle Proteins; Cell Line, Tumor; Epithelial Cells; Epithelial-Mesenchymal Transition; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hepatocyte Nuclear Factor 4; Histones; Humans; Lung Neoplasms; Nuclear Proteins; Phenotype; Proto-Oncogene Protein c-ets-2; RNA, Small Interfering; Sequence Analysis, RNA; Signal Transduction; Smad3 Protein; Survival Analysis; Transcription Factors; Transcriptome; Transforming Growth Factor beta; Triazoles | 2016 |
Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients.
Topics: Adenocarcinoma; Apoptosis; Chemokine CCL5; Chemokines; Chemotaxis; Clinical Trials, Phase I as Topic; Clodronic Acid; Colorectal Neoplasms; Cyclohexanes; Humans; Interferon-alpha; Liver Neoplasms; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Macrophages; Maraviroc; Molecular Targeted Therapy; Neoplasm Invasiveness; Neoplasm Proteins; NG-Nitroarginine Methyl Ester; Phenylurea Compounds; Pilot Projects; Pyridines; Receptors, CCR5; STAT3 Transcription Factor; Survival Analysis; Triazoles; Tumor Cells, Cultured; Tumor Microenvironment | 2016 |
Effects of letrozole on breast cancer micro-metastatic tumor growth in bone and lung in mice inoculated with murine 4T1 cells.
Topics: Animals; Aromatase Inhibitors; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Letrozole; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Neoplasm Micrometastasis; Nitriles; Triazoles | 2016 |
Hsp90 Inhibitor Ganetespib Sensitizes Non-Small Cell Lung Cancer to Radiation but Has Variable Effects with Chemoradiation.
Topics: A549 Cells; Animals; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chemoradiotherapy; Female; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Mice; Mice, Nude; Paclitaxel; Radiation-Sensitizing Agents; Triazoles; Xenograft Model Antitumor Assays | 2016 |
NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation.
Topics: Animals; Azepines; Benzamides; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Diphenylamine; Enhancer Elements, Genetic; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression; Gene Knockdown Techniques; Genes, ras; Histone-Lysine N-Methyltransferase; Histones; Humans; Lung Neoplasms; MAP Kinase Kinase Kinases; Methylation; Mice; Mice, Nude; Nuclear Proteins; Repressor Proteins; Transcription Factors; Transcription, Genetic; Triazoles; Xenograft Model Antitumor Assays | 2016 |
Inhibition of BET bromodomain-dependent XIAP and FLIP expression sensitizes KRAS-mutated NSCLC to pro-apoptotic agents.
Topics: A549 Cells; Acetanilides; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azepines; Benzodiazepines; Carcinoma, Non-Small-Cell Lung; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Cycle; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 3-Ring; Humans; Lung Neoplasms; Mice, SCID; Mutation; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins p21(ras); Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Triazoles; X-Linked Inhibitor of Apoptosis Protein; Xenograft Model Antitumor Assays | 2016 |
MYCL is a target of a BET bromodomain inhibitor, JQ1, on growth suppression efficacy in small cell lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Azepines; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 6; Drug Resistance, Neoplasm; Gene Amplification; Gene Expression; Gene Expression Profiling; Humans; Lung Neoplasms; Proto-Oncogene Proteins c-myc; Small Cell Lung Carcinoma; Transcriptome; Triazoles | 2016 |
Molecular and functional evaluation of a novel HIF inhibitor, benzopyranyl 1,2,3-triazole compound.
Topics: A549 Cells; Angiogenesis Inhibitors; Animals; Carcinoma, Lewis Lung; Chick Embryo; Chorioallantoic Membrane; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; HEK293 Cells; Human Umbilical Vein Endothelial Cells; Humans; Hydroxylation; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mice, Inbred C57BL; Neovascularization, Physiologic; Protein Stability; Proteolysis; Response Elements; Signal Transduction; Time Factors; Transfection; Triazoles; Tumor Burden; Tumor Hypoxia; Tumor Microenvironment; Ubiquitination; Vascular Endothelial Growth Factor A | 2017 |
Combination Therapy of NSCLC Using Hsp90 Inhibitor and Doxorubicin Carrying Functional Nanoceria.
Topics: A549 Cells; Acrylic Resins; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cerium; Combined Modality Therapy; Doxorubicin; Drug Carriers; Folic Acid; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Nanoparticles; Rats; Reactive Oxygen Species; Triazoles | 2017 |
[Two Cases of Lung Metastasis from Breast Cancer Successfully Treated with Endocrine Therapy].
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Estradiol; Estrogen Receptor Antagonists; Female; Fulvestrant; Humans; Letrozole; Lung Neoplasms; Nitriles; Treatment Outcome; Triazoles | 2016 |
The BET bromodomain inhibitor JQ1 radiosensitizes non-small cell lung cancer cells by upregulating p21.
Topics: Animals; Azepines; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Radiation Tolerance; Triazoles; Up-Regulation | 2017 |
Estrogen receptor (ER) and epidermal growth factor receptor (EGFR) as targets for dual lung cancer therapy: not just a case?
Topics: Adenocarcinoma; Antineoplastic Agents; Diagnosis, Differential; Drug Therapy, Combination; ErbB Receptors; Female; Follow-Up Studies; Gefitinib; Humans; Letrozole; Lung Neoplasms; Middle Aged; Nitriles; Protein Kinase Inhibitors; Quinazolines; Receptors, Estrogen; Skin Neoplasms; Triazoles | 2008 |
A case of benign metastasizing leiomyoma treated by surgical castration followed by an aromatase inhibitor, anastrozole.
Topics: Anastrozole; Aromatase Inhibitors; Fallopian Tubes; Female; Humans; Hysterectomy; Leiomyoma; Lung Neoplasms; Middle Aged; Nitriles; Ovariectomy; Triazoles; Uterine Neoplasms | 2009 |
Recurrent endometrial carcinoma regression with the use of the aromatase inhibitor anastrozole.
Topics: Adenocarcinoma; Anastrozole; Aromatase Inhibitors; Endometrial Neoplasms; Female; Humans; Immunohistochemistry; Lung Neoplasms; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Receptors, Estrogen; Tomography, X-Ray Computed; Triazoles | 2008 |
[A case of recurrent breast cancer with multiple lung metastases responding to anastrozole monotherapy].
Topics: Anastrozole; Biomarkers, Tumor; Breast Neoplasms; Female; Humans; Lung Neoplasms; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Radiography; Triazoles | 2008 |
Synthesis and cytotoxic profile of glycosyl-triazole linked to 1,2,4-oxadiazole moiety at C-5 through a straight-chain carbon and oxygen atoms.
Topics: Antineoplastic Agents; Carbon; Carcinoma; Cell Line, Tumor; Cell Proliferation; Glycosylation; Humans; Laryngeal Neoplasms; Lung Neoplasms; Oxadiazoles; Oxygen; Triazoles | 2009 |
Synthesis, structure elucidation and antitumour activity of N-substituted amides of 3-(3-ethylthio-1,2,4-triazol-5-yl)propenoic acid.
Topics: Amides; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Female; Fibroblasts; Humans; Lung Neoplasms; Skin; Triazoles | 2009 |
A newly developed lung nodule during chemotherapy for small cell lung cancer. Chronic necrotising pulmonary aspergillosis.
Topics: Aged; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chronic Disease; Etoposide; Humans; Lung Neoplasms; Male; Pulmonary Aspergillosis; Pyrimidines; Small Cell Lung Carcinoma; Triazoles; Voriconazole | 2009 |
Feasibility trial of letrozole in combination with bevacizumab in patients with metastatic breast cancer.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Feasibility Studies; Female; Follow-Up Studies; Humans; Letrozole; Lung Neoplasms; Lymphatic Metastasis; Middle Aged; Neoplasm Staging; Nitriles; Prognosis; Soft Tissue Neoplasms; Survival Rate; Treatment Outcome; Triazoles | 2010 |
Evaluation of the value of attribution in the interpretation of adverse event data: a North Central Cancer Treatment Group and American College of Surgeons Oncology Group investigation.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Benzamides; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase III as Topic; Double-Blind Method; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Lung Neoplasms; Male; Middle Aged; Piperazines; Placebos; Pyrimidines; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Rate; Treatment Outcome; Triazoles; Young Adult | 2010 |
Fungal spinal cord compression in metastatic synovial sarcoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Diagnosis, Differential; Disease Progression; Fatal Outcome; Female; Fractures, Spontaneous; Humans; Lung Neoplasms; Mycoses; Neoplasm Recurrence, Local; Neoplasm Staging; Osteomyelitis; Pneumonectomy; Pyrimidines; Radiotherapy, Adjuvant; Sarcoma, Synovial; Spinal Cord Compression; Spinal Cord Neoplasms; Triazoles; Voriconazole | 2011 |
Cytohesins are cytoplasmic ErbB receptor activators.
Topics: Adenocarcinoma; Animals; Dimerization; ErbB Receptors; Gene Knockdown Techniques; GTPase-Activating Proteins; Guanine Nucleotide Exchange Factors; Humans; Lung Neoplasms; Mice; Neoplasm Transplantation; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases; Signal Transduction; Transplantation, Heterologous; Triazoles | 2010 |
Inhibition of neutrophil infiltration into A549 lung tumors in vitro and in vivo using a CXCR2-specific antagonist is associated with reduced tumor growth.
Topics: Adenocarcinoma; Animals; Blotting, Western; Cell Proliferation; Chemotaxis; Culture Media, Conditioned; Enzyme-Linked Immunosorbent Assay; Humans; Immunoenzyme Techniques; In Vitro Techniques; Lung Neoplasms; Melanoma; Mice; Mice, Inbred BALB C; Mice, SCID; Neutrophil Infiltration; Quinazolines; Receptors, Interleukin-8B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spheroids, Cellular; Triazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2011 |
EW-7195, a novel inhibitor of ALK5 kinase inhibits EMT and breast cancer metastasis to lung.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Epithelial-Mesenchymal Transition; Female; Hep G2 Cells; Humans; Luciferases; Lung Neoplasms; Mice; Mice, Transgenic; Neoplasm Invasiveness; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Smad2 Protein; Triazoles | 2011 |
[Lymphangioleiomyomatosis: new therapeutic approaches].
Topics: Adult; Aromatase Inhibitors; Clinical Trials, Phase II as Topic; Doxycycline; Estrogen Receptor Modulators; Female; Humans; Letrozole; Lung Neoplasms; Lung Transplantation; Lymphangioleiomyomatosis; Matrix Metalloproteinase Inhibitors; Multicenter Studies as Topic; Nitriles; Randomized Controlled Trials as Topic; Registries; Sirolimus; Spain; Therapies, Investigational; Triazoles | 2011 |
A painful thigh lesion in an immunocompromised 11-year-old boy.
Topics: Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Humans; Hyphae; Immunocompromised Host; Lung Neoplasms; Male; Pyrimidines; Pythiosis; Pythium; Sarcoma, Ewing; Thigh; Triazoles; Voriconazole | 2011 |
In-vitro cytotoxicity and cell cycle analysis of two novel bis-1,2, 4-triazole derivatives: 1,4-bis[5-(5-mercapto-1,3,4-oxadiazol-2-yl-methyl)-thio-4-(p-tolyl)-1,2,4-triazol-3-yl]-butane (MNP-14) and 1,4-bis[5-(carbethoxy-methyl)-thio-4-(p-ethoxy phenyl)-
Topics: Antineoplastic Agents; Apoptosis; Butanes; Cell Cycle; Cell Line, Tumor; Humans; Lung Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Triazoles | 2011 |
Ganetespib (STA-9090), a nongeldanamycin HSP90 inhibitor, has potent antitumor activity in in vitro and in vivo models of non-small cell lung cancer.
Topics: Animals; Antineoplastic Agents; Benzoquinones; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Female; HSP90 Heat-Shock Proteins; Humans; Intramolecular Oxidoreductases; Lactams, Macrocyclic; Lung Neoplasms; Mice; Mice, SCID; Prostaglandin-E Synthases; Protein Binding; Protein Stability; Triazoles; Xenograft Model Antitumor Assays | 2012 |
Anti-proliferative effect of cytohesin inhibition in gefitinib-resistant lung cancer cells.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cytoplasm; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; ErbB Receptors; Gefitinib; Gene Expression Regulation, Neoplastic; Guanine Nucleotide Exchange Factors; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Neoplasm Transplantation; Quinazolines; Receptor, IGF Type 1; Signal Transduction; Triazoles | 2012 |
Successful combination: existing drugs boost cancer vaccine responses.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Cancer Vaccines; Daclizumab; Disease Models, Animal; Female; Humans; Immunoglobulin G; Letrozole; Lung Neoplasms; Membrane Glycoproteins; Mice; Nitriles; Treatment Outcome; Triazoles | 2012 |
Prevention of tobacco carcinogen-induced lung cancer in female mice using antiestrogens.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Carcinogens; Cell Proliferation; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Immunoenzyme Techniques; Lung Neoplasms; Mice; Mice, Inbred BALB C; Nicotiana; Nitriles; Nitrosamines; Receptors, Estrogen; Triazoles | 2012 |
Co-expression of estrogen receptor beta and aromatase in Japanese lung cancer patients: gender-dependent clinical outcome.
Topics: Aged; Androgens; Aromatase; Aromatase Inhibitors; Asian People; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Estrogen Receptor beta; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Letrozole; Lung; Lung Neoplasms; Male; Middle Aged; Nitriles; Sex Factors; Testosterone; Treatment Outcome; Triazoles | 2012 |
The synergistic effect of EGFR tyrosine kinase inhibitor gefitinib in combination with aromatase inhibitor anastrozole in non-small cell lung cancer cell lines.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Synergism; ErbB Receptors; Estrogen Receptor alpha; Estrogen Receptor beta; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Gene Expression; Humans; Inhibitory Concentration 50; Lung Neoplasms; MAP Kinase Signaling System; Nitriles; Protein Kinase Inhibitors; Protein Transport; Proto-Oncogene Proteins c-akt; Quinazolines; Triazoles | 2012 |
Targeting KRAS-mutant non-small cell lung cancer with the Hsp90 inhibitor ganetespib.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Female; Genes, ras; Humans; Imidazoles; Lung Neoplasms; Mice; Mice, Nude; Mutation; Phosphoinositide-3 Kinase Inhibitors; Quinolines; Signal Transduction; TOR Serine-Threonine Kinases; Triazoles; Xenograft Model Antitumor Assays | 2012 |
The iron chelator, deferasirox, as a novel strategy for cancer treatment: oral activity against human lung tumor xenografts and molecular mechanism of action.
Topics: Administration, Oral; Animals; Antigens, CD; Antineoplastic Agents; Apoptosis; Benzoates; Cell Cycle; Cell Line, Tumor; Copper; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Deferasirox; Female; Humans; Iron; Iron Chelating Agents; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Neuroectodermal Tumors, Primitive, Peripheral; Protein Serine-Threonine Kinases; Receptors, Transferrin; Small Cell Lung Carcinoma; Transplantation, Heterologous; Triazoles; Zinc | 2013 |
Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Azepines; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Screening Assays, Antitumor; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Lung Neoplasms; Molecular Targeted Therapy; Nuclear Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Signal Transduction; Transcription Factors; Triazoles | 2012 |
Multiple analyses of G-protein coupled receptor (GPCR) expression in the development of gefitinib-resistance in transforming non-small-cell lung cancer.
Topics: Adenosine A2 Receptor Antagonists; Antineoplastic Agents; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fibroblasts; Gefitinib; Humans; Lung; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Pyrimidines; Quinazolines; Receptor, Adenosine A2A; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcriptome; Triazoles | 2012 |
Remarkable photocytotoxicity of a novel triazole-linked cationic porphyrin-β-carboline conjugate.
Topics: Antineoplastic Agents; Carbolines; Cell Line, Tumor; Humans; Lung Neoplasms; Metalloporphyrins; Photochemotherapy; Porphyrins; Triazoles; Zinc | 2013 |
Acute cerebrovascular accident after cisplatin treatment in a patient taking letrozole.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Female; Hemianopsia; Humans; Letrozole; Lung Neoplasms; Middle Aged; Nitriles; Stroke; Triazoles | 2012 |
[Advanced breast cancer with lung and pleural metastases responsive to anastrozole--a case report].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Lung Neoplasms; Middle Aged; Nitriles; Pleural Effusion, Malignant; Pleural Neoplasms; Postmenopause; Receptors, Estrogen; Triazoles | 2002 |
CAI inhibits the growth of small cell lung cancer cells.
Topics: Animals; Antineoplastic Agents; Carcinoma, Small Cell; Cell Division; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasms, Experimental; Neovascularization, Pathologic; Transplantation, Heterologous; Triazoles; Tumor Cells, Cultured | 2003 |
Ultralow doses of various drugs in chemotherapy of experimental tumors.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Indazoles; Leukemia P388; Lung Neoplasms; Melanoma; Mice; Mitomycin; Neoplasm Metastasis; Neoplasms, Experimental; Triazoles; Xenograft Model Antitumor Assays | 2003 |
[CHEMICAL AND PHARMACOLOGICAL STUDY OF NITROFURAZONE ANALOGUES WITH RESPECT TO THEIR THERAPEUTIC ACTION ON MALIGNANT EMBRYOMA OF THE TESTIS].
Topics: Antineoplastic Agents; Humans; Lung Neoplasms; Male; Mice; Neoplasm Metastasis; Neoplasms; Nitrofurazone; Pharmacology; Rats; Research; Teratoma; Testicular Neoplasms; Thiosemicarbazones; Triazoles | 1964 |
[Three cases of advanced breast cancer successfully treated with a weekly dose of paclitaxel].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Mastectomy, Modified Radical; Middle Aged; Neoplasm Invasiveness; Nitriles; Paclitaxel; Skin Neoplasms; Sternum; Triazoles | 2005 |
Durable response of metastatic endometrial carcinoma to treatment with fulvestrant (Faslodex) after prior progestin and anastrozole therapy.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Endometrial Neoplasms; Estradiol; Female; Fulvestrant; Humans; Lung Neoplasms; Nitriles; Progestins; Triazoles | 2006 |
Aromatase inhibitors in human lung cancer therapy.
Topics: Anastrozole; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Carcinoma, Non-Small-Cell Lung; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoblotting; Immunoenzyme Techniques; Lung Neoplasms; Male; Mice; Mice, Nude; Nitriles; Ovariectomy; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Heterologous; Triazoles | 2005 |
Photodynamic therapy for solitary retinal metastasis from breast carcinoma.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Female; Humans; Lung Neoplasms; Middle Aged; Nitriles; Photochemotherapy; Retinal Neoplasms; Triazoles | 2006 |
Leuprolide acetate plus aromatase inhibition for male breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Bone Neoplasms; Breast Neoplasms, Male; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Humans; Letrozole; Leuprolide; Lung Neoplasms; Lymphatic Metastasis; Male; Mastectomy, Modified Radical; Middle Aged; Nitriles; Receptors, Estrogen; Receptors, Progesterone; Treatment Outcome; Triazoles | 2006 |
A CK2-dependent mechanism for degradation of the PML tumor suppressor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Casein Kinase II; Cell Line; Cell Line, Transformed; Cell Line, Tumor; Enzyme Activation; Enzyme Inhibitors; Genes, Tumor Suppressor; Green Fluorescent Proteins; Hemagglutinins; Humans; Leupeptins; Lung Neoplasms; Mice; Mice, Transgenic; Molecular Sequence Data; Neoplasm Proteins; NIH 3T3 Cells; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promyelocytic Leukemia Protein; Proteasome Endopeptidase Complex; Protein Structure, Tertiary; Protein Subunits; RNA, Small Interfering; Sequence Deletion; Serine; Sorbitol; Transcription Factors; Transcriptional Activation; Triazoles; Tumor Suppressor Proteins; Ubiquitin | 2006 |
Inhibition of vascular endothelial growth factor (VEGF)-165 and semaphorin 3A-mediated cellular invasion and tumor growth by the VEGF signaling inhibitor ZD4190 in human colon cancer cells and xenografts.
Topics: Animals; Cisplatin; Colonic Neoplasms; Enzyme Inhibitors; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Piperidines; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Semaphorin-3A; Signal Transduction; Triazoles; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2006 |
Effects of quercetin on beta-apo-8'-carotenal-induced DNA damage and cytochrome P1A2 expression in A549 cells.
Topics: Antioxidants; Benzo(a)pyrene; beta Carotene; Blotting, Western; Carotenoids; Cell Line, Tumor; Comet Assay; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; DNA Breaks; Drug Interactions; Enzyme Inhibitors; Humans; Lipid Peroxidation; Lung Neoplasms; Quercetin; Triazoles | 2006 |
[Pulmonary metastases from endometrial stromal sarcoma may benefit from hormone therapy].
Topics: Aromatase Inhibitors; Endometrial Neoplasms; Female; Humans; Letrozole; Lung Neoplasms; Middle Aged; Nitriles; Sarcoma, Endometrial Stromal; Triazoles; Uterine Neoplasms | 2007 |
Metastatic uterine leiomyosarcoma regression using an aromatase inhibitor.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Combined Modality Therapy; Female; Humans; Hysterectomy; Immunohistochemistry; Leiomyosarcoma; Lung Neoplasms; Middle Aged; Nitriles; Remission Induction; Treatment Outcome; Triazoles; Uterine Neoplasms | 2007 |
Role of gonadotropin-releasing hormone analog in the management of male metastatic breast cancer is uncertain.
Topics: Androgens; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms, Male; Goserelin; Humans; Letrozole; Lung Neoplasms; Male; Middle Aged; Nitriles; Triazoles | 2007 |
Long-term disease-free survival after hormonal therapy of a patient with recurrent low grade endometrial stromal sarcoma: a case report.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Disease-Free Survival; Endometrial Neoplasms; Female; Goserelin; Humans; Lung Neoplasms; Neoplasm Recurrence, Local; Nitriles; Sarcoma, Endometrial Stromal; Triazoles | 2009 |
Clinical pharmacokinetic study and sensitive effect of AK-2123.
Topics: Adult; Aged; Female; Humans; Lung Neoplasms; Male; Middle Aged; Radiation-Sensitizing Agents; Triazoles | 1994 |
Structure-function analysis of signal and growth inhibition by carboxyamido-triazole, CAI.
Topics: Aminoimidazole Carboxamide; Animals; Antineoplastic Agents; Arachidonic Acid; Calcium; Cell Division; CHO Cells; Cricetinae; Cricetulus; Humans; Lung Neoplasms; Signal Transduction; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured | 1994 |
Augmentation of tumor metastasis by platelet-activating factor.
Topics: Animals; Antineoplastic Agents; Azepines; Female; Interleukin-1; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Platelet Activating Factor; Triazoles; Tumor Necrosis Factor-alpha | 1996 |
Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with downregulation of Bcl-2.
Topics: Animals; Apoptosis; DNA Fragmentation; Down-Regulation; Genetic Vectors; Interferon-gamma; Interleukin-1; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C3H; Mice, Nude; Nitric Oxide; Proto-Oncogene Proteins c-bcl-2; Transfection; Triazoles; Tumor Cells, Cultured | 1997 |
Technetium-99m-cyclam AK 2123: a novel marker for tumor hypoxia.
Topics: Animals; Cell Hypoxia; Female; Lung Neoplasms; Mammary Neoplasms, Experimental; Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Tissue Distribution; Triazoles | 2001 |
Efficacy of anastrozole in male breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Neoplasms; Breast Neoplasms, Male; Combined Modality Therapy; Enzyme Inhibitors; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Nitriles; Treatment Failure; Triazoles | 2002 |
Phase II study of 1,2,4-triglycidylurazol (TGU) in previously untreated and treated patients with small cell lung cancer.
Topics: Aged; Antineoplastic Agents; Carcinoma, Small Cell; Drug Evaluation; Humans; Lung Neoplasms; Middle Aged; Prognosis; Triazoles | 1987 |
Small cell lung cancer: results of a phase II study of 1,2,4 triglycidylurazol.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Drug Evaluation; Humans; Leukocyte Count; Lung Neoplasms; Nausea; Platelet Count; Triazoles | 1986 |
Phase II trial of anaxirone in advanced non-small cell lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Triazoles | 1987 |
Guanazole in the treatment of advanced bronchogenic carcinoma: a pilot study of the Southeastern Cancer Study Group.
Topics: Adult; Aged; Carcinoma, Bronchogenic; Female; Guanazole; Humans; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Triazoles | 1986 |
[Morphologic characteristics of spontaneous tumors and leukoses in 1st generation C47B1XCBA hybrid mice].
Topics: Adenoma; Animals; Carcinogens; Carcinoma, Hepatocellular; Leukemia, Experimental; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Mice; Neoplasms, Experimental; Triazoles | 1969 |
The inhibition of catalase by plasma and by human tissue extracts.
Topics: Ascorbic Acid; Blood; Carcinoma; Catalase; Conductometry; Dialysis; Edetic Acid; Erythrocytes; Ethylmaleimide; Hemolysis; Hot Temperature; Humans; Kidney; Liver; Lung Neoplasms; Male; Neoplasms; Prostatic Neoplasms; Stomach Neoplasms; Tissue Extracts; Triazoles | 1969 |
[A comparative evaluation of the toxic and possible carcinogenic effect of benzotriazol and phenidon].
Topics: Animals; Carcinogens; Chemical and Drug Induced Liver Injury; Female; Fibroma; Leukemia, Experimental; Lung Diseases; Lung Neoplasms; Male; Mesentery; Mice; Neoplasms, Experimental; Rats; Sarcoma, Experimental; Splenic Diseases; Triazoles | 1970 |