Compounds > triazoles
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triazoles and Long QT Syndrome

triazoles has been researched along with Long QT Syndrome in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (28.57)29.6817
2010's12 (57.14)24.3611
2020's3 (14.29)2.80

Authors

AuthorsStudies
Liao, X; Yu, Z1
Anderson, K; Kearney, BP; Kwan, E; Mathias, A; Namour, F; Qin, A; Xin, Y; Yun, C; Zheng, H1
Han, D; Li, J; Luo, C; Shi, T; Yan, Y; Zhang, Y; Zheng, X1
Belardinelli, L; Bezzina, CR; Casini, S; Hoekstra, M; Mengarelli, I; Portero, V; Rajamani, S; Remme, CA; Veldkamp, MW; Verkerk, AO; Wilde, AAM1
Hanretty, AM; Langelier, C; Trang, TP; Yang, K1
Dunzo, E; Fan, L; Heber, W; Hussaini, A; Iwamoto, M; Khalilieh, SG; Liu, R; Triantafyllou, I; Yee, KL1
Cutler, DL; Lin, WH; Tendolkar, A; Troyer, MD; Wang, Z; Xuan, F1
Karamouzos, V; Matzaroglou, C; Panos, G; Tylianakis, M; Velissaris, D1
Mason, JW1
Balez, S; Dumortier, T; Sechaud, R1
Shah, RR1
Atalay, S; Aypar, E; Çiftçi, E; Ileri, T; Ince, E; Kendirli, T; Tutar, E1
Kochanek, M; Michels, G; Pfister, R; Shimabukuro-Vornhagen, A1
Cil, H; Elbey, MA; Islamoglu, Y; Onturk, E1
Belardinelli, L; Crumb, W; Dhalla, AK; El-Bizri, N; Hirakawa, R; Hu, L; Karpinski, S; Koltun, D; Li, CH; Li, XJ; Liu, G; Rajamani, S; Shryock, JC; Smith-Maxwell, C; Wang, WQ; Wu, L; Yao, L; Zablocki, J1
Estes, LL; Wilson, JW; Zeuli, JD1
Hackett, LP; Isbister, GK1
Nolin, TD; Owens, RC1
Amedro, P; Blayac, JP; Cociglio, M; Eiden, C; Hillaire-Buys, D; Margueritte, G; Peyrière, H; Tichit, R1
Denning, DW; Williams, KJ1
Chu, J; Henderson, W; Hoffman, R1

Reviews

2 review(s) available for triazoles and Long QT Syndrome

ArticleYear
Drug-induced QT interval shortening: potential harbinger of proarrhythmia and regulatory perspectives.
    British journal of pharmacology, 2010, Volume: 159, Issue:1

    Topics: Animals; Anticonvulsants; Drug Approval; Drug Design; Drug-Related Side Effects and Adverse Reactions; Humans; KATP Channels; Legislation, Drug; Long QT Syndrome; Triazoles

2010
Antimicrobial-associated QT interval prolongation: pointes of interest.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Dec-15, Volume: 43, Issue:12

    Topics: Anti-Infective Agents; Antifungal Agents; Biomarkers; Fluoroquinolones; Humans; Imidazoles; Ketolides; Long QT Syndrome; Macrolides; Torsades de Pointes; Triazoles

2006

Trials

4 trial(s) available for triazoles and Long QT Syndrome

ArticleYear
Filgotinib, a JAK1 Inhibitor, Has No Effect on QT Interval in Healthy Subjects.
    Clinical pharmacology in drug development, 2020, Volume: 9, Issue:1

    Topics: Adult; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Healthy Volunteers; Heart Rate; Humans; Janus Kinase 1; Long QT Syndrome; Male; Middle Aged; Protein Kinase Inhibitors; Pyridines; Triazoles

2020
A Randomized Trial to Assess the Effect of Doravirine on the QTc Interval Using a Single Supratherapeutic Dose in Healthy Adult Volunteers.
    Clinical drug investigation, 2017, Volume: 37, Issue:10

    Topics: Adolescent; Adult; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Fluoroquinolones; Heart Rate; Humans; Long QT Syndrome; Male; Middle Aged; Moxifloxacin; Pyridones; Reverse Transcriptase Inhibitors; Triazoles; Young Adult

2017
Preladenant, a selective adenosine A₂A receptor antagonist, is not associated with QT/QTc prolongation.
    European journal of clinical pharmacology, 2013, Volume: 69, Issue:10

    Topics: Adenosine A2 Receptor Antagonists; Adolescent; Adult; Antiparkinson Agents; Aza Compounds; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Female; Fluoroquinolones; Humans; Long QT Syndrome; Male; Middle Aged; Moxifloxacin; Pyrimidines; Quinolines; Triazoles; Young Adult

2013
Deferasirox does not induce QT/QTc-prolongation in healthy subjects.
    International journal of clinical pharmacology and therapeutics, 2009, Volume: 47, Issue:5

    Topics: Adolescent; Adult; Aged; Area Under Curve; Aza Compounds; Benzoates; Deferasirox; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Fluoroquinolones; Humans; Iron Chelating Agents; Long QT Syndrome; Male; Middle Aged; Moxifloxacin; Quinolines; Triazoles; Young Adult

2009

Other Studies

15 other study(ies) available for triazoles and Long QT Syndrome

ArticleYear
Torsade de Pointes/QT Prolongation Associated with Antifungal Triazoles: A Pharmacovigilance Study Based on the U.S. FDA Adverse Event Reporting System（FAERS）.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2022, Volume: 25

    Topics: Antifungal Agents; Bayes Theorem; DNA-Binding Proteins; Humans; Long QT Syndrome; Pharmacovigilance; Retrospective Studies; Software; Torsades de Pointes; Triazoles

2022
Pharmacological corrections of the mutant hERG channels by posaconazole.
    Clinical and experimental pharmacology & physiology, 2021, Volume: 48, Issue:6

    Topics: Electrophysiological Phenomena; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Heterozygote; Humans; Long QT Syndrome; Patch-Clamp Techniques; Triazoles

2021
Anti-arrhythmic potential of the late sodium current inhibitor GS-458967 in murine Scn5a-1798insD+/- and human SCN5A-1795insD+/- iPSC-derived cardiomyocytes.
    Cardiovascular research, 2017, Jun-01, Volume: 113, Issue:7

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cell Line; Epicardial Mapping; Female; Genetic Predisposition to Disease; Heart Rate; Induced Pluripotent Stem Cells; Isolated Heart Preparation; Kinetics; Long QT Syndrome; Male; Mice, Transgenic; Mutation; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Phenotype; Pyridines; Triazoles; Voltage-Gated Sodium Channel Blockers

2017
Use of isavuconazole in a patient with voriconazole-induced QTc prolongation.
    Transplant infectious disease : an official journal of the Transplantation Society, 2017, Volume: 19, Issue:4

    Topics: Antifungal Agents; Cystic Fibrosis; Female; Humans; Long QT Syndrome; Lung Transplantation; Nitriles; Pyridines; Triazoles; Voriconazole; Young Adult

2017
Long QT Syndrome Leading to Multiple Cardiac Arrests After Posaconazole Administration in an Immune-Compromised Patient with Sepsis: An Unusual Case Report.
    The American journal of case reports, 2016, Apr-29, Volume: 17

    Topics: Adult; Antifungal Agents; Female; Heart Arrest; Humans; Immunocompromised Host; Long QT Syndrome; Sepsis; Surgical Wound Infection; Triazoles

2016
Antimicrobials and QT prolongation.
    The Journal of antimicrobial chemotherapy, 2017, 05-01, Volume: 72, Issue:5

    Topics: Anti-Bacterial Agents; Education, Medical; Humans; Ketolides; Long QT Syndrome; Macrolides; Potassium Channels, Inwardly Rectifying; Practice Patterns, Physicians'; Torsades de Pointes; Triazoles

2017
Voriconazole-induced QT interval prolongation and torsades de pointes.
    Pediatrics international : official journal of the Japan Pediatric Society, 2011, Volume: 53, Issue:5

    Topics: Adolescent; Antifungal Agents; Child; Electrocardiography; Endocarditis; Female; Humans; Long QT Syndrome; Male; Pulmonary Aspergillosis; Pyrimidines; Torsades de Pointes; Triazoles; Trichosporonosis; Voriconazole

2011
[53-year-old woman with life-threatening complications after use of ciprofloxacin and posaconazol].
    Deutsche medizinische Wochenschrift (1946), 2012, Volume: 137, Issue:4

    Topics: Anti-Infective Agents; Cardiopulmonary Resuscitation; Ciprofloxacin; Electrocardiography; Female; Humans; Leukemia; Long QT Syndrome; Middle Aged; Risk Factors; Triazoles

2012
OTc prolongation and torsade de pointes ventricular tachycardia in a small dose voriconazole therapy.
    European review for medical and pharmacological sciences, 2012, Volume: 16, Issue:1

    Topics: Adult; Antifungal Agents; Cardiac Pacing, Artificial; Cardiopulmonary Resuscitation; Electric Countershock; Electrocardiography; Electrolytes; Female; Humans; Long QT Syndrome; Mitral Valve Insufficiency; Nephrotic Syndrome; Pyrimidines; Rheumatic Heart Disease; Torsades de Pointes; Triazoles; Voriconazole

2012
A novel, potent, and selective inhibitor of cardiac late sodium current suppresses experimental arrhythmias.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 344, Issue:1

    Topics: Acetanilides; Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiotonic Agents; Cnidarian Venoms; Female; Flecainide; Heart Conduction System; Long QT Syndrome; Mutation; Myocardial Ischemia; Myocytes, Cardiac; Patch-Clamp Techniques; Piperazines; Potassium Channel Blockers; Pyridines; Quaternary Ammonium Compounds; Rabbits; Ranolazine; Sodium Channel Blockers; Triazoles

2013
Effect of combined fluoroquinolone and azole use on QT prolongation in hematology patients.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:3

    Topics: Adult; Aged; Antifungal Agents; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Female; Fluconazole; Hematologic Neoplasms; Humans; Hypokalemia; Levofloxacin; Long QT Syndrome; Male; Middle Aged; Mycoses; Ofloxacin; Pyrimidines; Risk Factors; Torsades de Pointes; Triazoles; Ventricular Dysfunction, Left; Voriconazole

2013
Nefazodone poisoning: toxicokinetics and toxicodynamics using continuous data collection.
    Journal of toxicology. Clinical toxicology, 2003, Volume: 41, Issue:2

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Antidotes; Biotransformation; Blood Pressure; Charcoal; Depressive Disorder; Drug Overdose; Electrocardiography; Female; Fluid Therapy; Half-Life; Humans; Long QT Syndrome; Piperazines; Triazoles

2003
Inherited long QT syndrome revealed by antifungals drug-drug interaction.
    Journal of clinical pharmacy and therapeutics, 2007, Volume: 32, Issue:3

    Topics: Acute Disease; Adolescent; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Female; Genotype; Humans; Injections, Intravenous; Leukemia, Myeloid; Long QT Syndrome; Mixed Function Oxygenases; Mucormycosis; Pyrimidines; Torsades de Pointes; Triazoles; Voriconazole

2007
Termination of development of D0870.
    The Journal of antimicrobial chemotherapy, 2001, Volume: 47, Issue:5

    Topics: Animals; Antifungal Agents; Drug Design; Drug Industry; Humans; Long QT Syndrome; Triazoles

2001
QTc prolongation and drugs.
    Clinical pharmacology and therapeutics, 2001, Volume: 70, Issue:6

    Topics: Antidepressive Agents, Second-Generation; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Histamine H1 Antagonists; Humans; Long QT Syndrome; Loratadine; Oxidoreductases, N-Demethylating; Piperazines; Triazoles

2001