triazoles has been researched along with Leukemia in 77 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (5.19) | 18.7374 |
| 1990's | 2 (2.60) | 18.2507 |
| 2000's | 22 (28.57) | 29.6817 |
| 2010's | 43 (55.84) | 24.3611 |
| 2020's | 6 (7.79) | 2.80 |
| Authors | Studies |
|---|---|
| Abulkhair, HS; Fayed, EA; Husseiny, EM; Othman, EM | 1 |
| Chen, A; Li, X; Si, H; Xuan, B; Yang, W | 1 |
| Alali, M; Balsara, K; Barros, KL; Budnick, HC; Khaitan, A; Schulte, RR; Streicher, DA | 1 |
| Abdullah, KG; Agar, NYR; Asara, JM; Bird, CE; Bonal, DM; Buehler, J; Cahill, DP; Cameron, AB; Dang, T; DeBerardinis, RJ; Endress, JE; Evans, L; Gao, W; Gattie, LC; Gradl, S; Guo, L; Harris, IS; Huang, B; Janzer, A; Jeffers, M; Jennings, RB; Kaelin, WG; Khanal, J; Kornblum, HI; Lee, JH; Lee, S; Lehrman, MA; Levitt, MM; Ligon, KL; Lin, YF; Looper, RE; Losman, JA; Ly, P; Mak, TW; Martin-Sandoval, MS; Mathews, TP; McBrayer, SK; Nguyen, QD; Puliyappadamba, VT; Regan, MS; Richardson, TE; Savani, MR; Shi, DD; Signoretti, S; Stopka, SA; Sutter, A; Wang, AC; Xiao, Y; Xu, L; Xu, M; Zacharias, LG | 1 |
| Antony, J; Day, R; Gimenez, G; Horsfield, JA; Khatoon, U; Morison, IM; Taylor, T | 1 |
| Chan, SH; Guh, JH; Hou, DR; Hsu, JL; Leu, WJ; Swain, SP | 1 |
| Chen, Q; Gu, J; Li, N; Li, S; Wang, W; Wang, X; Wang, Z; Zhao, G | 1 |
| Ai, H; Chen, J; Han, M; Hu, J; Huang, H; Huang, X; Ji, Y; Liang, Y; Ma, J; Meng, F; Tang, Y; Wu, D; Zhang, R; Zhang, X | 1 |
| Liu, J; Ouyang, L; Yao, D | 1 |
| Ho, CL; Lee, CH; Lin, C; Lin, JC; Sun, M; Yen, WT | 1 |
| Elmi, L; Graham, A; Grundy, M; Hall, M; Jones, T; Pallis, M; Russell, N; Seedhouse, C | 1 |
| Bai, CG; Chen, Y; He, DD; Li, HY; Sun, TY; Zhang, Q; Zhao, XJ | 1 |
| Berman, E; Epstein, DJ; Frattini, MG; Huang, YT; Klimek, VM; Papanicolaou, GA; Park, JH; Seo, SK; Tallman, MS | 1 |
| Bose, P; DiPippo, AJ; Kontoyiannis, DP; Rausch, CR | 1 |
| DiPippo, AJ; Kontoyiannis, DP; Rausch, CR | 1 |
| Kwa, LHA; Lee, HLW; Lim, TP; Tan, BH; Tan, SYM; Tan, TT; Tang, SLS; Wong, GC; Zhou, PY | 1 |
| Itälä-Remes, M; Remes, K; Salmenniemi, U | 1 |
| Goletz, G; Groll, AH; Jürgens, H; Kolve, H; Pieper, S; Yunus, S | 1 |
| Bastow, S; Chevassut, TJ; Horne, GA; Stewart, HJ | 1 |
| Bradner, JE; Cerulli, R; Frank, DA; Liu, S; Nelson, EA; Qi, J; Stone, RM; Toniolo, PA; Wadleigh, M; Walker, SR; Xiang, M | 1 |
| Günther, S; Lucas, X | 1 |
| Jung, DS; Kontoyiannis, DP; Tverdek, FP | 1 |
| Imanishi, S; Ohsuga, M; Ohyashiki, JH; Ohyashiki, K; Takahashi, R | 1 |
| Araújo, DA; Camara, CA; Coulidiati, TH; Dantas, BB; de Oliveira, RN; do Nascimento, WS; Faheina-Martins, GV; Gomes, ER; Gonçalves, JC; Lara, A; Oliveira, EJ | 1 |
| Bhushan, S; Chinthakindi, PK; Guru, SK; Khan, I; Koul, S; Rath, SK; Sangwan, PL; Singh, B | 1 |
| Annino, L; Arcioni, F; Bertaina, A; Carotti, A; Caselli, D; Cassetta, MI; Cerchiara, E; Chierichini, A; Cupelli, L; Del Principe, MI; Di Gioia, M; Fallani, S; Fanci, R; Girmenia, C; Mariotti, B; Mengarelli, A; Minotti, C; Novelli, A; Perriello, V; Piedimonte, M; Proia, A; Ribersani, M; Spadea, A; Torelli, GF | 1 |
| Akiti, T; Barreiros, G; Nouér, SA; Nucci, M; Trope, BM; Varon, AG | 1 |
| Bradner, JE; DeAngelo, SL; Dhe-Paganon, S; Paulk, J; Roberts, JM; Scott, TG; Seo, HS; Souza, A; Tanaka, M | 1 |
| Chang, YC; Cheng, HC; Feng, CC; Huang, YT; Lin, CL; Lin, HT; Lo, WJ; Yeh, SP | 1 |
| Ananda-Rajah, MR; Grigg, A; Slavin, MA | 1 |
| Akdogan, E; Aksoy, F; Altunayoglu, V; Aydin, K; Koksal, I; Omay, SB; Sozen, EE; Yilmaz, M | 1 |
| Bandettini, R; Calvillo, M; Castagnola, E; Conte, M; Cuzzubbo, D; Faraci, M; Lanino, E; Manzitti, C; Miano, M; Micalizzi, C; Morreale, G; Pescetto, L; Ravegnani, M; Ricagni, L; Soro, O | 1 |
| Bailly, C; Baldeyrou, B; Beauchard, A; Besson, T; Chérouvrier, JR; Domon, L; Jaunet, A; Lansiaux, A; Murillo, L; Picot, L; Thiéry, V | 1 |
| Wingard, J | 1 |
| Alberti, D; Arruga, F; Bracco, E; Carturan, S; Cilloni, D; Defilippi, I; Greco, E; Maffè, C; Messa, E; Messa, F; Pautasso, M; Pellegrino, RM; Roetto, A; Rosso, V; Rotolo, A; Saglio, G; Zanone, C | 1 |
| Abecasis, M; Bilger, K; Bofarull, RM; Cordonnier, C; Cornely, OA; de la Cámara, R; Einsele, H; Faucher, C; Heussel, CP; Liakopoulou, E; Ljungman, P; Maertens, J; Olavarria, E; Pigneux, A; Pineau, M; Rovira, M; Ullmann, AJ; Weisser, M | 1 |
| Cordonnier, C; Cornely, OA; Flückiger, U; Frêre, P; Gachot, B; Heinz, WJ; Herbrecht, R; Lass-Flörl, C; Maertens, J; Marchetti, O; Ribaud, P; Thiebaut, A | 1 |
| Berger, P; Caillot, D; Dupont, B; Gangneux, JP; Herbrecht, R; Lafuma, A; Michallet, M; Moreau, P; O'Sullivan, AK; Ribaud, P | 1 |
| Deeren, D | 1 |
| Cordonnier, C; Cornely, OA; Einsele, H; Ljungman, P; Maertens, J; Rovira, M | 1 |
| Kurokawa, M; Masamoto, Y; Nannya, Y | 1 |
| Brizio, A; Cantoni, S; Lombardi, G; Morra, E; Nosari, A; Riva, M | 1 |
| Anderes, K; Chevrel, MC; Drygin, D; Haddach, M; Macalino, D; Nédellec, AS; O'Brien, SE; Pierre, F; Regan, CF; Ryckman, DM; Siddiqui-Jain, A; Stefan, E; Streiner, N | 1 |
| Demitrovicova, A; Kisac, P; Krcmery, V | 1 |
| Bahcebasi, S; Cetin, M; Deniz, K; Eser, B; Kaynar, L; Kurnaz, F; Ozturk, A; Pala, C; Sivgin, S; Unal, A; Uzer, E | 1 |
| Kontoyiannis, DP | 1 |
| Kochanek, M; Michels, G; Pfister, R; Shimabukuro-Vornhagen, A | 1 |
| Best, L; Champlin, RE; Georgiadou, SP; Kontoyiannis, DP; Lewis, RE; Torres, HA | 1 |
| Campo, M; Chaftari, AM; Hachem, RY; Jiang, Y; Kassis, C; Prince, RA; Raad, II; Ramos, E; Wang, W | 1 |
| Maxmen, A | 1 |
| Bojtarova, E; Cetkovsky, P; Drgona, L; Foralova, R; Forsterova, K; Guman, T; Haber, J; Kandrnal, V; Kocmanova, I; Kouba, M; Mallatova, N; Masarova, L; Mayer, J; Mudry, P; Muzik, J; Racil, Z; Sejnova, D; Tothova, E; Vydra, J; Weinbergerova, B; Ziakova, B | 1 |
| Cornely, OA; Heinz, WJ; Hertenstein, B; Horst, HA; Löffler, J; Maschmeyer, G; Requadt, C; Ruhnke, M; Wagner, T | 1 |
| Barkai, G; Jacoby, E; Keller, N | 1 |
| Cook, C; Fernandez, C; Fraser, R; McCully, B; Schmidt, M; Shouldice, E | 1 |
| Cappelli, B; Castagnola, E; Dodero, P; Faraci, M; Machetti, M; Molinari, AC; Morreale, G; Tomà, P | 1 |
| Bastié, JN; Bretagne, S; Castaigne, S; Chehata, S; Cordonnier, C; Kuentz, M; Maury, S; Pautas, C; Ribaud, P | 1 |
| Bonatti, H; Dierich, MP; Freund, MC; Gastl, G; Gschwendtner, A; Gunsilius, E; Kropshofer, G; Lass-Flörl, C; Petzer, A | 1 |
| Afif, C; Bodey, GP; Boktour, MR; Chatzinikolaou, I; Cooksley, C; Hachem, RY; Kantarjian, HM; Kontoyiannis, DP; Perego, C; Raad, II | 1 |
| Alexander, BD; Long, GD; Miller, JL; Perfect, JR; Schell, WA | 1 |
| Carde, A; Faure, P; Papy, E; Ribaud, P; Touratier, S | 1 |
| Dombrowski, F; Franke, A; Jentsch-Ullrich, K; Koenigsmann, M; Mohren, M; Schalk, E | 1 |
| Corcoran, G; Graybill, JR; Hachem, RY; Hare, R; Herbrecht, R; Kontoyiannis, DP; Raad, II | 1 |
| Antin, JH; Baden, LR; Campbell, BJ; Cutler, CS; Fiumara, K; Lowry, CM; Marty, FM | 1 |
| Augustin, E; Konopa, J; Moś-Rompa, A; Skwarska, A; Witkowski, JM | 1 |
| Arisaka, O; Fujisawa, M; Fukushima, K; Hagisawa, S; Kurosawa, H; Matsunaga, T; Nakajima, D; Sugita, K | 1 |
| Calvo, C; de Andoin, NG; Guerrero, R; Landa, J; Nogues, A; Onate, E; Uriz, J | 1 |
| Bonini, A; Caira, M; Fianchi, L; Girmenia, C; Leone, G; Pagano, L; Rossi, G; Sanguinetti, M; Valentini, CG | 1 |
| Hogan, H; Howell, A; Lewis, R; Safdar, A | 1 |
| Denning, DW; Pasqualotto, AC; Shah, M; Wynn, R | 1 |
| Berceanu, A; Herbrecht, R | 1 |
| Anaissie, EJ; Andersson, BS; Bodey, GP; Champlin, RE; Giralt, SA; Kantarjian, HM; Karl, C; Kontoyiannis, DP; O'Brien, S; Vartivarian, S | 1 |
| Milatovic, D; Schwartz, S; Thiel, E | 1 |
| Bianchi, L; Cellai, C; Della Malva, N; Laurenzana, A; Paoletti, F; Vannucchi, AM | 1 |
| Levi, JA; Wiernik, PH | 1 |
| Fukawa, H; Kodama, F; Maruta, A; Matsuzaki, M | 1 |
| Hojo, H; Lin, KY; Torii, Y; Toyama, K; Tsuda, A; Yoshikawa, O | 1 |
| Clayton, JD; Shealy, YF | 1 |
4 review(s) available for triazoles and Leukemia
| Article | Year |
|---|---|
Therapeutic potential of 1,2,3-triazole hybrids for leukemia treatment.
Topics: Antineoplastic Agents; Humans; Leukemia; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles | 2022 |
Efficacy and safety of micafungin versus extensive azoles in the prevention and treatment of invasive fungal infections for neutropenia patients with hematological malignancies: A meta-analysis of randomized controlled trials.
Topics: Adolescent; Adult; Antifungal Agents; Child; Echinocandins; Female; Humans; Leukemia; Lipopeptides; Male; Micafungin; Middle Aged; Mycoses; Neutropenia; Randomized Controlled Trials as Topic; Triazoles | 2017 |
Invasive mycoses: strategies for effective management.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Antifungal Agents; Antineoplastic Agents; Aspartate Aminotransferases; Aspergillosis; Bilirubin; Biomarkers; Drug Monitoring; Echinocandins; Female; Flucytosine; Humans; Immunocompromised Host; Leukemia; Liver; Liver Function Tests; Male; Middle Aged; Mucormycosis; Mycoses; Myelodysplastic Syndromes; Opportunistic Infections; Pneumonia; Risk Factors; Triazoles | 2012 |
Zygomycoses in patients with acute leukaemia.
Topics: Amphotericin B; Antifungal Agents; Female; Humans; Immunocompromised Host; Leukemia; Male; Middle Aged; Neutropenia; Pyrimidines; Triazoles; Voriconazole; Zygomycosis | 2006 |
7 trial(s) available for triazoles and Leukemia
| Article | Year |
|---|---|
Micafungin versus posaconazole prophylaxis in acute leukemia or myelodysplastic syndrome: A randomized study.
Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Antifungal Agents; Chemoprevention; Female; Humans; Incidence; Leukemia; Male; Micafungin; Middle Aged; Mycoses; Myelodysplastic Syndromes; Neutropenia; Survival Analysis; Treatment Failure; Triazoles | 2018 |
Voriconazole for secondary prophylaxis of invasive fungal infections in allogeneic stem cell transplant recipients: results of the VOSIFI study.
Topics: Adult; Aged; Antifungal Agents; Female; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Leukemia; Male; Middle Aged; Mycoses; Pyrimidines; Transplantation, Homologous; Treatment Outcome; Triazoles; Voriconazole; Young Adult | 2010 |
Comparison of posaconazole versus weekly amphotericin B lipid complex for the prevention of invasive fungal infections in hematopoietic stem-cell transplantation.
Topics: Administration, Oral; Adult; Aged; Amphotericin B; Antifungal Agents; Female; Hematopoietic Stem Cell Transplantation; Humans; Infusions, Intravenous; Leukemia; Lipids; Lymphoma; Male; Middle Aged; Mycoses; Prospective Studies; Risk; Tacrolimus; Time Factors; Transplantation, Homologous; Triazoles | 2012 |
Immediate versus deferred empirical antifungal (IDEA) therapy in high-risk patients with febrile neutropenia: a randomized, double-blind, placebo-controlled, multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Double-Blind Method; Female; Fever; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Middle Aged; Mycoses; Neutropenia; Placebos; Pyrimidines; Triazoles; Voriconazole | 2013 |
Posaconazole as salvage treatment for invasive fusariosis in patients with underlying hematologic malignancy and other conditions.
Topics: Adult; Aged; Amphotericin B; Antifungal Agents; Female; Fusarium; Humans; Leukemia; Male; Middle Aged; Mycoses; Retrospective Studies; Salvage Therapy; Treatment Outcome; Triazoles | 2006 |
Effectiveness of an oral triazole for opportunistic mold infections in patients with cancer: experience with SCH 39304.
Topics: Administration, Oral; Adult; Aged; Antifungal Agents; Female; Humans; Leukemia; Male; Middle Aged; Mycoses; Neoplasms; Opportunistic Infections; Prospective Studies; Triazoles | 1993 |
A comparative clinical trial of 5-azacytidine and guanazole in previously treated adults with acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Azacitidine; Digestive System; Female; Fever; Guanazole; Humans; Infusions, Parenteral; Leukemia; Leukopenia; Male; Middle Aged; Remission, Spontaneous; Time Factors; Triazoles | 1976 |
66 other study(ies) available for triazoles and Leukemia
| Article | Year |
|---|---|
Apoptosis induction, PARP-1 inhibition, and cell cycle analysis of leukemia cancer cells treated with novel synthetic 1,2,3-triazole-chalcone conjugates.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Drug Screening Assays, Antitumor; Humans; Leukemia; Molecular Docking Simulation; Molecular Structure; Poly(ADP-ribose) Polymerase Inhibitors; Structure-Activity Relationship; Triazoles | 2022 |
Successful isavuconazole salvage therapy for cerebral mucormycosis in a child with relapsed leukemia: A light in the dark tunnel.
Topics: Antifungal Agents; Child; Humans; Leukemia; Mucormycosis; Nitriles; Salvage Therapy; Triazoles | 2023 |
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma.
Topics: Animals; Brain Neoplasms; Enzyme Inhibitors; Glioma; Isocitrate Dehydrogenase; Leukemia; Mice; Mutation; Pyrimidines; Salicylanilides; Triazoles | 2022 |
BET inhibition prevents aberrant RUNX1 and ERG transcription in STAG2 mutant leukaemia cells.
Topics: Azepines; Base Sequence; Cell Cycle Proteins; Core Binding Factor Alpha 2 Subunit; Gene Expression Regulation, Leukemic; Humans; K562 Cells; Leukemia; Mutation; Proteins; Transcription, Genetic; Transcriptional Regulator ERG; Triazoles | 2020 |
Mechanistic Study of Triazole Based Aminodiol Derivatives in Leukemic Cells-Crosstalk between Mitochondrial Stress-Involved Apoptosis and Autophagy.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Calcium; Cell Line, Tumor; Cell Survival; Gene Regulatory Networks; HL-60 Cells; Humans; Leukemia; Mitochondria; Models, Biological; Molecular Structure; Signal Transduction; Stress, Physiological; Transcription, Genetic; Transcriptome; Triazoles | 2020 |
Synergistic inhibitory effects of deferasirox in combination with decitabine on leukemia cell lines SKM-1, THP-1, and K-562.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Benzoates; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Decitabine; Deferasirox; Drug Synergism; Gene Expression Regulation; Humans; Iron Chelating Agents; Leukemia; Reactive Oxygen Species; Triazoles | 2017 |
Primary fungal prophylaxis in acute leukemia patients with different risk factors: retrospective analysis from the CAESAR study.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Asian People; Central Venous Catheters; Child; Child, Preschool; Consolidation Chemotherapy; Female; Humans; Incidence; Induction Chemotherapy; Infant; Leukemia; Male; Middle Aged; Mycoses; Neutropenia; Retrospective Studies; Risk Factors; Serum Albumin; Sex Factors; Triazoles; Young Adult | 2017 |
What structural modifications can be used for BRD4 inhibitors for their use in leukemia therapy?
Topics: Aminoquinolines; Azepines; Benzoates; Cell Cycle Proteins; Histone Deacetylases; Humans; Leukemia; Nuclear Proteins; Protein Interaction Domains and Motifs; Small Molecule Libraries; Transcription Factors; Triazoles | 2017 |
Predicting effective pro-apoptotic anti-leukaemic drug combinations using co-operative dynamic BH3 profiling.
Topics: Antineoplastic Agents; Apoptosis; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Drug Combinations; Humans; Indoles; Leukemia; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Triazoles | 2018 |
Design and synthesis of novel dasatinib derivatives as inhibitors of leukemia stem cells.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Dasatinib; Drug Design; Drug Screening Assays, Antitumor; Humans; Leukemia; Mice; Neoplastic Stem Cells; Oxadiazoles; Triazoles | 2018 |
Breakthrough Fungal Infections in Patients With Leukemia Receiving Isavuconazole.
Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Candidemia; Electronic Health Records; Female; Humans; Invasive Fungal Infections; Leukemia; Male; Middle Aged; Nitriles; Pyridines; Retrospective Studies; Triazoles; Young Adult | 2018 |
Tolerability of isavuconazole after posaconazole toxicity in leukaemia patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Leukemia; Liver Function Tests; Male; Middle Aged; Mycoses; Nitriles; Pyridines; Retrospective Studies; Triazoles; Young Adult | 2019 |
Subtherapeutic posaconazole troughs despite high-dose posaconazole tablets in a patient with terminal ileum resection.
Topics: Humans; Ileum; Leukemia; Micafungin; Myelodysplastic Syndromes; Tablets; Triazoles | 2019 |
Outcome of allogeneic SCT in patients with pre-transplant invasive fungal infection.
Topics: Antibiotic Prophylaxis; Antifungal Agents; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Mycoses; Triazoles | 2013 |
Azole-based chemoprophylaxis of invasive fungal infections in paediatric patients with acute leukaemia: an internal audit.
Topics: Adolescent; Antifungal Agents; Chemoprevention; Child; Child, Preschool; Cohort Studies; Female; Humans; Infant; Leukemia; Male; Mycoses; Retrospective Studies; Treatment Outcome; Triazoles; Voriconazole | 2014 |
BRD4 associates with p53 in DNMT3A-mutated leukemia cells and is implicated in apoptosis by the bromodomain inhibitor JQ1.
Topics: Apoptosis; Azepines; Caspases; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferases; DNA Breaks, Double-Stranded; DNA Methyltransferase 3A; Humans; Leukemia; Mutation; Nuclear Proteins; Nucleophosmin; Transcription Factors; Triazoles; Tumor Suppressor Protein p53 | 2013 |
Targeting STAT5 in hematologic malignancies through inhibition of the bromodomain and extra-terminal (BET) bromodomain protein BRD2.
Topics: Azepines; Benzodiazepines; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Hematologic Neoplasms; Humans; Leukemia; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; RNA, Small Interfering; STAT5 Transcription Factor; Transcription Factors; Triazoles | 2014 |
Targeting the BET family for the treatment of leukemia.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Azepines; Benzodiazepines; Cell Cycle Proteins; Cell Proliferation; Gene Expression; Humans; Leukemia; Nuclear Proteins; Protein Serine-Threonine Kinases; Quinazolines; Quinazolinones; RNA-Binding Proteins; Transcription Factors; Triazoles | 2014 |
Switching from posaconazole suspension to tablets increases serum drug levels in leukemia patients without clinically relevant hepatotoxicity.
Topics: Administration, Oral; Adult; Aged; Antifungal Agents; Female; Food-Drug Interactions; Gastrointestinal Absorption; Humans; Leukemia; Liver; Male; Middle Aged; Mycoses; Suspensions; Tablets; Triazoles | 2014 |
Effect of combined deferasirox and 5-azacytidine treatment on human leukemia cells in vitro.
Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzoates; Deferasirox; HL-60 Cells; Humans; Iron Chelating Agents; Leukemia; Triazoles; U937 Cells | 2015 |
Distinct effects of novel naphtoquinone-based triazoles in human leukaemic cell lines.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle Proteins; Cell Proliferation; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Inhibitory Concentration 50; K562 Cells; Leukemia; Membrane Potential, Mitochondrial; Molecular Structure; Naphthoquinones; Oxidative Stress; Reactive Oxygen Species; S Phase Cell Cycle Checkpoints; Structure-Activity Relationship; Triazoles | 2015 |
A novel triazole derivative of betulinic acid induces extrinsic and intrinsic apoptosis in human leukemia HL-60 cells.
Topics: Antineoplastic Agents; Apoptosis; Betulinic Acid; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Leukemia; Molecular Structure; Pentacyclic Triterpenes; Structure-Activity Relationship; Triazoles; Triterpenes | 2016 |
Posaconazole oral suspension primary prophylaxis in acute leukemia and allogeneic stem cell transplant patients: can it be used without measurement of plasma concentration?
Topics: Administration, Oral; Adolescent; Adult; Aged; Antifungal Agents; Child; Child, Preschool; Female; Humans; Immunocompromised Host; Leukemia; Male; Middle Aged; Mycoses; Plasma; Prospective Studies; Stem Cell Transplantation; Transplantation, Homologous; Triazoles; Young Adult | 2016 |
Antimold Prophylaxis May Reduce the Risk of Invasive Fusariosis in Hematologic Patients with Superficial Skin Lesions with Positive Culture for Fusarium.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antifungal Agents; Female; Fusariosis; Fusarium; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Intertrigo; Leukemia; Male; Middle Aged; Onychomycosis; Prospective Studies; Skin; Triazoles; Voriconazole; Young Adult | 2016 |
Design and characterization of bivalent BET inhibitors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azepines; Cell Cycle Proteins; Cell Proliferation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Humans; Leukemia; Ligands; Mice; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Nuclear Proteins; Small Molecule Libraries; Structure-Activity Relationship; Transcription Factors; Triazoles | 2016 |
Deferasirox has strong anti-leukemia activity but may antagonize theanti-leukemia effect of doxorubicin.
Topics: Antineoplastic Agents; Apoptosis; Benzoates; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deferasirox; Doxorubicin; Extracellular Signal-Regulated MAP Kinases; Humans; Iron; Leukemia; Phosphorylation; Reactive Oxygen Species; Triazoles | 2017 |
Breakthrough disseminated Scedosporium prolificans infection in a patient with relapsed leukaemia on prolonged voriconazole followed by posaconazole prophylaxis.
Topics: Administration, Oral; Antifungal Agents; Antineoplastic Agents; Fatal Outcome; Humans; Leukemia; Male; Middle Aged; Mycetoma; Opportunistic Infections; Pyrimidines; Recurrence; Scedosporium; Triazoles; Voriconazole | 2008 |
Voriconazole-induced neuropathy.
Topics: Adolescent; Adult; Female; Humans; Leukemia; Male; Nervous System Diseases; Pyrimidines; Triazoles; Voriconazole | 2008 |
Voriconazole for cryptococcal meningitis in children with leukemia or receiving allogeneic hemopoietic stem cell transplant.
Topics: Adolescent; Antifungal Agents; Antineoplastic Agents; Child; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Leukemia; Male; Meningitis, Cryptococcal; Pyrimidines; Transplantation, Homologous; Triazoles; Voriconazole | 2009 |
Synthesis and antitumoral activity of novel thiazolobenzotriazole, thiazoloindolo[3,2-c]quinoline and quinolinoquinoline derivatives.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA; DNA Topoisomerases, Type I; Female; Humans; Indoles; Leukemia; Quinolines; Thiazoles; Topoisomerase I Inhibitors; Triazoles | 2009 |
Antifungal management.
Topics: Amphotericin B; Antifungal Agents; Cord Blood Stem Cell Transplantation; Echinocandins; Humans; Leukemia; Lung; Male; Middle Aged; Neutropenia; Postoperative Complications; Pulmonary Aspergillosis; Pyrimidines; Triazoles; Voriconazole | 2010 |
Deferasirox is a powerful NF-kappaB inhibitor in myelodysplastic cells and in leukemia cell lines acting independently from cell iron deprivation by chelation and reactive oxygen species scavenging.
Topics: Aged; Aged, 80 and over; Apoptosis; Benzoates; Blotting, Western; Deferasirox; Electrophoretic Mobility Shift Assay; Female; Flow Cytometry; Fluorescent Antibody Technique; Humans; Iron; Iron Chelating Agents; K562 Cells; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes; NF-kappa B; Protein Binding; Reactive Oxygen Species; Triazoles | 2010 |
European guidelines for antifungal management in leukemia and hematopoietic stem cell transplant recipients: summary of the ECIL 3--2009 update.
Topics: Antifungal Agents; Aspergillosis; Candidiasis; Caspofungin; Echinocandins; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Leukemia; Lipopeptides; Micafungin; Mycoses; Neutropenia; Opportunistic Infections; Pyrimidines; Triazoles; Voriconazole | 2011 |
Cost effectiveness of posaconazole in the prophylaxis of invasive fungal infections in acute leukaemia patients for the French healthcare system.
Topics: Acute Disease; Adult; Aged; Antibiotic Prophylaxis; Antifungal Agents; Cost-Benefit Analysis; Decision Trees; Female; France; Fungi; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Mycoses; National Health Programs; Triazoles | 2011 |
Treatment of invasive aspergillosis with nonmyeloablative allogeneic stem cell transplantation: one stone two birds.
Topics: Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Humans; Immunosuppression Therapy; Invasive Pulmonary Aspergillosis; Leukemia; Pyrimidines; Radiography; Remission Induction; Stem Cell Transplantation; Transplantation Conditioning; Transplantation, Homologous; Triazoles; Voriconazole | 2011 |
Voriconazole as secondary antifungal prophylaxis in stem cell transplant recipients.
Topics: Antifungal Agents; Humans; Leukemia; Mycoses; Pyrimidines; Stem Cell Transplantation; Triazoles; Voriconazole | 2011 |
Voriconazole is effective as secondary antifungal prophylaxis in leukemia patients with prior pulmonary fungal disease: case series and review of literature.
Topics: Adult; Aged; Antifungal Agents; Antineoplastic Agents; Female; Humans; Leukemia; Lung Diseases, Fungal; Male; Middle Aged; Neutropenia; Pyrimidines; Treatment Outcome; Triazoles; Voriconazole | 2011 |
Oral voriconazole for neutropenia: a leukemia patient with probable pulmonary aspergillosis and scedosporidiosis.
Topics: Administration, Oral; Aged; Antifungal Agents; Female; Humans; Leukemia; Neutropenia; Pulmonary Aspergillosis; Pyrimidines; Triazoles; Voriconazole | 2011 |
7-(4H-1,2,4-Triazol-3-yl)benzo[c][2,6]naphthyridines: a novel class of Pim kinase inhibitors with potent cell antiproliferative activity.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Leukemia; Naphthyridines; Neoplasms; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-pim-1; Triazoles | 2011 |
Breakthrough fungemia due to Candida glabrata during posaconazole prophylaxis in hematology patients treated with anidulafungin - report of 5 cases.
Topics: Adult; Anidulafungin; Antifungal Agents; Candida glabrata; Candidiasis; Drug Resistance, Fungal; Echinocandins; Female; Fungemia; Humans; Immunocompromised Host; Leukemia; Male; Middle Aged; Slovakia; Treatment Outcome; Triazoles | 2011 |
Efficacy and safety of oral deferasirox treatment in the posttransplant period for patients who have undergone allogeneic hematopoietic stem cell transplantation (alloHSCT).
Topics: Adolescent; Adult; Benzoates; Deferasirox; Female; Hematopoietic Stem Cell Transplantation; Humans; Iron Chelating Agents; Iron Overload; Kidney; Leukemia; Leukemia, Myeloid, Acute; Liver; Male; Middle Aged; Phlebotomy; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation, Homologous; Triazoles; Young Adult | 2012 |
[53-year-old woman with life-threatening complications after use of ciprofloxacin and posaconazol].
Topics: Anti-Infective Agents; Cardiopulmonary Resuscitation; Ciprofloxacin; Electrocardiography; Female; Humans; Leukemia; Long QT Syndrome; Middle Aged; Risk Factors; Triazoles | 2012 |
The impact of prior invasive mold infections in leukemia patients who undergo allo-SCT in the era of triazole-based secondary prophylaxis.
Topics: Adolescent; Adult; Aged; Antibiotic Prophylaxis; Antifungal Agents; Child; Cohort Studies; Drug Therapy, Combination; Female; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Middle Aged; Mycoses; Retrospective Studies; Secondary Prevention; Transplantation, Homologous; Triazoles; Young Adult | 2013 |
Cancer research: Open ambition.
Topics: Adult; Animals; Azepines; Benzodiazepines; Cell Cycle Proteins; Child; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Leukemia; Male; Mice; Mutation; Neoplasm Proteins; Neoplasms; Nuclear Proteins; Oncogene Proteins; Oncogene Proteins, Fusion; Proto-Oncogene Proteins c-myc; Transcription Factors; Triazoles; Vorinostat; Young Adult | 2012 |
Invasive aspergillosis in patients with hematological malignancies in the Czech and Slovak republics: Fungal InfectioN Database (FIND) analysis, 2005-2009.
Topics: Acute Disease; Adolescent; Adult; Aged; Antifungal Agents; Aspergillosis; Bronchoalveolar Lavage Fluid; Child; Child, Preschool; Czech Republic; Databases, Factual; Echinocandins; Female; Galactose; Humans; Leukemia; Lung Diseases, Fungal; Male; Mannans; Middle Aged; Neutrophils; Pyrimidines; Retrospective Studies; Slovakia; Triazoles; Voriconazole; Young Adult | 2013 |
[Combination antifungal therapy in hematopoietic stem cell transplantation patients].
Topics: Amphotericin B; Antifungal Agents; Child; Dermatomycoses; Drug Therapy, Combination; Fusariosis; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Leukemia; Lung Diseases, Fungal; Male; Nasopharyngeal Diseases; Pyrimidines; Treatment Outcome; Triazoles; Voriconazole | 2012 |
Voriconazole treatment of presumptive disseminated Aspergillus infection in a child with acute leukemia.
Topics: Acute Disease; Adolescent; Amphotericin B; Antifungal Agents; Aspergillosis; Combined Modality Therapy; Debridement; Drug Therapy, Combination; Female; Hepatitis; Humans; Leukemia; Lung Diseases, Fungal; Opportunistic Infections; Osteomyelitis; Pyrimidines; Remission Induction; Sacroiliac Joint; Splenic Diseases; Triazoles; Voriconazole | 2003 |
Caspofungin associated with liposomal amphotericin B or voriconazole for treatment of refractory fungal pneumonia in children with acute leukaemia or undergoing allogeneic bone marrow transplant.
Topics: Adolescent; Amphotericin B; Bone Marrow Transplantation; Caspofungin; Child; Drug Therapy, Combination; Echinocandins; Humans; Leukemia; Lipopeptides; Liposomes; Male; Peptides; Peptides, Cyclic; Pneumonia; Pyrimidines; Transplantation, Homologous; Triazoles; Voriconazole | 2004 |
Secondary antifungal prophylaxis with voriconazole to adhere to scheduled treatment in leukemic patients and stem cell transplant recipients.
Topics: Adolescent; Adult; Antifungal Agents; Aspergillosis; Aspergillus; Candida; Candidiasis; Female; Graft vs Host Disease; Humans; Leukemia; Male; Middle Aged; Prognosis; Prospective Studies; Pyrimidines; Recurrence; Risk; Stem Cell Transplantation; Transplantation, Homologous; Triazoles; Voriconazole | 2004 |
Diagnosing invasive aspergillosis during antifungal therapy by PCR analysis of blood samples.
Topics: Adult; Aged; Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus; Base Sequence; Bronchoalveolar Lavage Fluid; DNA Primers; DNA, Fungal; Humans; Leukemia; Middle Aged; Neoplasms; Polymerase Chain Reaction; Pyrimidines; Transplantation; Triazoles; Voriconazole | 2004 |
Aspergillus terreus: an emerging amphotericin B-resistant opportunistic mold in patients with hematologic malignancies.
Topics: Adult; Aged; Amphotericin B; Aspergillosis; Aspergillus; Aspergillus fumigatus; Cross Infection; Drug Resistance, Fungal; Female; Humans; Leukemia; Male; Middle Aged; Neutropenia; Opportunistic Infections; Retrospective Studies; Risk Factors; Triazoles | 2004 |
Candida glabrata fungemia in transplant patients receiving voriconazole after fluconazole.
Topics: Adolescent; Adult; Candida glabrata; Female; Fluconazole; Fungemia; Humans; Leukemia; Male; Microbial Sensitivity Tests; Pyrimidines; Stem Cell Transplantation; Triazoles; Voriconazole | 2005 |
[Voriconazole at Saint Louis Hospital (Paris): Analysis of two-years of compassionate use].
Topics: Acute Disease; Antifungal Agents; Aspergillosis; Candidiasis; Cohort Studies; Fusarium; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Leukemia; Mycoses; Pyrimidines; Retrospective Studies; Time Factors; Treatment Outcome; Triazoles; Voriconazole | 2006 |
Voriconazole and sirolimus coadministration after allogeneic hematopoietic stem cell transplantation.
Topics: Adult; Antifungal Agents; Cord Blood Stem Cell Transplantation; Creatinine; Dose-Response Relationship, Drug; Drug Evaluation; Drug Interactions; Female; Graft Rejection; Graft vs Host Disease; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Leukemia; Lipids; Male; Middle Aged; Mycoses; Peripheral Blood Stem Cell Transplantation; Postoperative Complications; Pyrimidines; Retrospective Studies; Sirolimus; Transplantation, Homologous; Triazoles; Voriconazole | 2006 |
Induction of G2/M phase arrest and apoptosis of human leukemia cells by potent antitumor triazoloacridinone C-1305.
Topics: Acridines; Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Cell Division; Cell Line, Tumor; Cell Proliferation; Electrophoresis, Agar Gel; Flow Cytometry; G2 Phase; HL-60 Cells; Humans; In Situ Nick-End Labeling; Intracellular Membranes; Leukemia; Membrane Potentials; Mitochondria; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Triazoles | 2006 |
[Treatment with voriconazole for invasive fungal infection during chemotherapy for leukemia: doses and plasma concentration of voriconazole in children].
Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Drug Monitoring; Female; Humans; Immunocompromised Host; Infant; Leukemia; Male; Metabolic Clearance Rate; Mycoses; Neutropenia; Pyrimidines; Triazoles; Voriconazole | 2007 |
Secondary prophylaxis with voriconazole in a leukemic patient with pulmonary aspergillosis.
Topics: Antifungal Agents; Aspergillosis; Child, Preschool; Female; Humans; Immunocompromised Host; Leukemia; Lung Diseases, Fungal; Pyrimidines; Triazoles; Voriconazole | 2007 |
Scedosporiosis in patients with acute leukemia: a retrospective multicenter report.
Topics: Acute Disease; Adolescent; Adult; Aged; Amphotericin B; Anti-Bacterial Agents; Child; Child, Preschool; Humans; Leukemia; Male; Middle Aged; Mycetoma; Pyrimidines; Retrospective Studies; Scedosporium; Triazoles; Voriconazole | 2008 |
Progressive fusariosis: unpredictable posaconazole bioavailability, and feasibility of recombinant interferon-gamma plus granulocyte macrophage-colony stimulating factor for refractory disseminated infection.
Topics: Adult; Biological Availability; Fusarium; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunocompromised Host; Interferon-gamma; Leukemia; Male; Mycoses; Neutropenia; Recombinant Proteins; Salvage Therapy; Treatment Outcome; Triazoles | 2008 |
Voriconazole plasma monitoring.
Topics: Antifungal Agents; Aspergillosis; Child; Child, Preschool; Drug Administration Schedule; Drug Monitoring; Humans; Leukemia; Opportunistic Infections; Pyrimidines; Triazoles; Voriconazole | 2008 |
Beta-D-glucan detection test: a step toward preemptive therapy for fungal infections in leukemic patients?
Topics: Antifungal Agents; Antigens, Fungal; Aspergillosis; beta-Glucans; Candidiasis; Chemoprevention; Humans; Leukemia; Proteoglycans; Triazoles | 2008 |
Successful treatment of cerebral aspergillosis with a novel triazole (voriconazole) in a patient with acute leukaemia.
Topics: Acute Disease; Adolescent; Antifungal Agents; Aspergillosis; Brain Diseases; Humans; Leukemia; Male; Opportunistic Infections; Pyrimidines; Triazoles; Voriconazole | 1997 |
Specific PAF antagonist WEB-2086 induces terminal differentiation of murine and human leukemia cells.
Topics: Animals; Antineoplastic Agents; Azepines; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Histones; HL-60 Cells; Humans; K562 Cells; Kinetics; Leukemia; Leukemia, Erythroblastic, Acute; Mice; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Triazoles; Tumor Cells, Cultured | 2002 |
[Clinical evaluation of fluconazole in the case of deep mycosis associated with leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Antifungal Agents; Candidiasis; Drug Evaluation; Drug Tolerance; Female; Fluconazole; Humans; Injections, Intravenous; Leukemia; Lung Diseases, Fungal; Male; Middle Aged; Triazoles | 1989 |
[A clinical evaluation of injectable fluconazole in the treatment of deep mycosis associated with hematological malignancy].
Topics: Acute Disease; Adolescent; Adult; Aged; Antifungal Agents; Candida; Candidiasis; Drug Evaluation; Drug Tolerance; Female; Fluconazole; Humans; Injections, Intravenous; Leukemia; Lymphoma; Male; Middle Aged; Mycoses; Myelodysplastic Syndromes; Triazoles | 1989 |
Carbocyclic analog of purine ribonucleosides with antileukemic activity.
Topics: Aza Compounds; Carcinoma, Squamous Cell; Cells, Cultured; Humans; Leukemia; Neoplasms, Experimental; Purines; Ribonucleosides; Triazoles | 1973 |