Page last updated: 2024-08-24

triazoles and Lennox-Gastaut Syndrome

triazoles has been researched along with Lennox-Gastaut Syndrome in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's25 (69.44)24.3611
2020's11 (30.56)2.80

Authors

AuthorsStudies
García-Peñas, JJ; Gil Nagel-Rein, A; Sánchez-Carpintero, R; Villanueva-Haba, V1
Wang, C; Wang, J; Zhang, L1
Chez, M; Dixon-Salazar, T; Flamini, JR; Hyslop, A; McGoldrick, P; Millichap, JJ; Pina-Garza, JE; Resnick, T; Rho, JM; Sankar, R; Wolf, S1
Bozarth, XL; Oesch, G1
Caraballo, RH; Espeche, A; Fasulo, L; Galichio, S; Pociecha, J; Reyes, G; Semprino, M1
Auvin, S1
Aboumatar, S; Burdette, D; Chung, S; Kothare, S; Kuzniecky, R; Montouris, G; Rosenfeld, W1
Città, S; Ciuffini, R; Coppola, G; Elia, M; Manfredi, V; Marrelli, A; Operto, FF; Pastorino, GMG; Sole, M; Striano, P; Verrotti, A; Zucca, C1
Chou, P; Hsueh, SW; Huang, CS; Kuo, CC; Lai, YC; Lin, TH; Lin, YC; Wang, RW; Yang, YC1
Brigo, F; Eltze, C; Jones, K; Matricardi, S1
Dawman, L; Panda, P; Panda, PK; Sharawat, IK1
Auvin, S; Brandt, C; McMurray, R; Nikanorova, M1
Falip, M; McMurray, R; Santamarina, E; Striano, P1
Minagawa, K; Takayama, R; Watanabe, T1
Takahashi, Y; Takayama, R; Tsukamoto, K1
Kang, HC; Kim, HD; Kim, SH; Lee, JS1
Arzimanoglou, A; Bibbiani, F; Dhadda, S; Ferreira, J; Kumar, D; Olhaye, O; Satlin, A1
Chanda, K; M M, B; Maiti, B1
Chae, JH; Choi, JE; Hwang, YS; Kim, KJ; Kim, SH; Lee, JH; Lim, BC; Ryu, HW1
Della Bona, ML; Falchi, M; Guerrini, R; la Marca, G; Malvagia, S; Pellacani, S; Rosati, A1
Iyoda, K; Ohtsuka, Y; Shirasaka, Y; Takano, H; Takayama, R; Yoshinaga, H2
Cnaan, A; Dlugos, DJ; Kessler, SK; McCarthy, A1
Arzimanoglou, A; Bibbiani, F; Critchley, D; Dhadda, S; Ferreira, JA; Hussein, Z; Kumar, D; Mendes, S; Satlin, A; Schuck, E; Williams, B1
Becerra, JL; Burcet, J; Cano, A; Falip, M; Fernández, S; Fossas, P; Jaraba, S; Miravet, E; Miró, J; Molins, A; Pico, G; Raspall, M; Santamarina, E; Toledo, M1
Bibbiani, F; Kluger, G; Kothare, S; Olhaye, O; Perdomo, C; Sachdeo, R; Williams, B1
Balestri, A; Capovilla, G; Coppola, G; Curatolo, P; Fels, A; Franzoni, E; Grosso, S; Habetswallner, F; Mangano, S; Parisi, P; Pascotto, A; Spalice, A; Veggiotti, P; Verrotti, A; Zamponi, N1
Besag, FM1
Cerna, A; So, TY; Wier, HA1
Boor, R; Brandt, C; Jürgens, U; Korn-Merker, E; May, TW; Rambeck, B1
Arzimanoglou, A; Brown, LW; Flamini, R; Harrison, M; Kerr, M; Kluger, G; Kothare, S; Narurkar, M; Philip, S; Resnick, T1
Antzelevitch, C; Borggrefe, M; Brandt, C; Ebner, A; Göksu, T; Kuschyk, J; Papavassiliu, T; Rudic, B; Schimpf, R; Veltmann, C; Wolpert, C1
McCormack, PL1
Byeon, JH; Eun, BL; Eun, SH; Kang, HC; Kim, HD; Kim, SH; Kwon, EJ; Lee, JS; Lee, YM1
Capuano, A; Curatolo, P; Cusmai, R; Fusco, L; Moavero, R; Specchio, N; Vigevano, F1
Ko, TS; Lee, EH; Yum, MS1

Reviews

13 review(s) available for triazoles and Lennox-Gastaut Syndrome

ArticleYear
Cannabidiol for the treatment of Lennox-Gastaut syndrome and Dravet syndrome: experts' recommendations for its use in clinical practice in Spain.
    Revista de neurologia, 2021, 09-10, Volume: 73, Issue:S01

    Topics: Anticonvulsants; Cannabidiol; Clobazam; Clonazepam; Diazepam; Dioxolanes; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Epilepsies, Myoclonic; Humans; Lennox Gastaut Syndrome; Phenobarbital; Practice Guidelines as Topic; Pyrrolidinones; Spain; Triazoles; Valproic Acid

2021
Efficacy and safety of antiseizure medication for Lennox-Gastaut syndrome: a systematic review and network meta-analysis.
    Developmental medicine and child neurology, 2022, Volume: 64, Issue:3

    Topics: Anticonvulsants; Cannabidiol; Child; Humans; Lennox Gastaut Syndrome; Outcome Assessment, Health Care; Randomized Controlled Trials as Topic; Triazoles

2022
Proposed anti-seizure medication combinations with rufinamide in the treatment of Lennox-Gastaut syndrome: Narrative review and expert opinion.
    Seizure, 2023, Volume: 110

    Topics: Anticonvulsants; Child, Preschool; Clobazam; Expert Testimony; Humans; Lennox Gastaut Syndrome; Triazoles

2023
Lennox-Gastaut syndrome: New treatments and treatments under investigation.
    Revue neurologique, 2020, Volume: 176, Issue:6

    Topics: Anticonvulsants; Cannabidiol; Drug Development; Drugs, Investigational; Fenfluramine; Humans; Lennox Gastaut Syndrome; Nitriles; Pyridones; Therapies, Investigational; Triazoles

2020
Expert opinion: Proposed diagnostic and treatment algorithms for Lennox-Gastaut syndrome in adult patients.
    Epilepsy & behavior : E&B, 2020, Volume: 110

    Topics: Algorithms; Anticonvulsants; Clinical Trials as Topic; Clobazam; Electroencephalography; Expert Testimony; Humans; Intellectual Disability; Lennox Gastaut Syndrome; Sleep; Triazoles

2020
Anti-seizure medications for Lennox-Gastaut syndrome.
    The Cochrane database of systematic reviews, 2021, 04-07, Volume: 4

    Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Cannabidiol; Child; Child, Preschool; Cinnamates; Clobazam; Electroencephalography; Felbamate; Humans; Lamotrigine; Lennox Gastaut Syndrome; Middle Aged; Placebos; Randomized Controlled Trials as Topic; Topiramate; Triazoles; Wakefulness; Young Adult

2021
Efficacy and safety of rufinamide as adjunctive therapy in patients with Lennox Gastaut syndrome: A systematic review and Meta-analysis.
    Seizure, 2021, Volume: 91

    Topics: Anticonvulsants; Humans; Lennox Gastaut Syndrome; Randomized Controlled Trials as Topic; Seizures; Triazoles

2021
Rufinamide for the treatment of Lennox-Gastaut syndrome: evidence from clinical trials and clinical practice.
    Epileptic disorders : international epilepsy journal with videotape, 2018, Feb-01, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Humans; Infant; Lennox Gastaut Syndrome; Outcome Assessment, Health Care; Triazoles; Young Adult

2018
Dosing considerations for rufinamide in patients with Lennox-Gastaut syndrome: Phase III trial results and real-world clinical data.
    Seizure, 2017, Volume: 47

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Clinical Trials, Phase III as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Humans; Lennox Gastaut Syndrome; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles; Young Adult

2017
Rufinamide for the treatment of Lennox-Gastaut syndrome.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:5

    Topics: Biological Availability; Double-Blind Method; Electroencephalography; Half-Life; Humans; Intellectual Disability; Lennox Gastaut Syndrome; Placebos; Quality of Life; Randomized Controlled Trials as Topic; Spasms, Infantile; Triazoles

2011
Rufinamide for pediatric patients with Lennox-Gastaut syndrome: a comprehensive overview.
    Paediatric drugs, 2011, Apr-01, Volume: 13, Issue:2

    Topics: Animals; Child; Epilepsies, Partial; Humans; Intellectual Disability; Lennox Gastaut Syndrome; Spasms, Infantile; Treatment Outcome; Triazoles

2011
Rufinamide from clinical trials to clinical practice in the United States and Europe.
    Epileptic disorders : international epilepsy journal with videotape, 2011, Volume: 13 Suppl 1

    Topics: Anticonvulsants; Child; Child, Preschool; Europe; Humans; Intellectual Disability; Lennox Gastaut Syndrome; Randomized Controlled Trials as Topic; Seizures; Spasms, Infantile; Treatment Outcome; Triazoles; United States

2011
Rufinamide: a pharmacoeconomic profile of its use as adjunctive therapy in Lennox-Gastaut syndrome.
    PharmacoEconomics, 2012, Volume: 30, Issue:3

    Topics: Administration, Oral; Anticonvulsants; Cost-Benefit Analysis; Economics, Pharmaceutical; Humans; Intellectual Disability; Lennox Gastaut Syndrome; Models, Economic; Quality-Adjusted Life Years; Spasms, Infantile; Triazoles; United Kingdom

2012

Trials

9 trial(s) available for triazoles and Lennox-Gastaut Syndrome

ArticleYear
Real-world data on rufinamide treatment in patients with Lennox-Gastaut syndrome: Results from a European noninterventional registry study.
    Epilepsy & behavior : E&B, 2017, Volume: 76

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Ethnicity; Europe; European Union; Female; Humans; Lennox Gastaut Syndrome; Male; Registries; Seizures; Sleep Stages; Treatment Outcome; Triazoles

2017
Evaluation of long-term safety, tolerability, and behavioral outcomes with adjunctive rufinamide in pediatric patients (≥1 to <4 years old) with Lennox-Gastaut syndrome: Final results from randomized study 303.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2019, Volume: 23, Issue:1

    Topics: Anticonvulsants; Child; Child, Preschool; Female; Humans; Lennox Gastaut Syndrome; Male; Triazoles

2019
A pharmacokinetic study and correlation with clinical response of rufinamide in infants with epileptic encephalopathies.
    Pharmacology, 2013, Volume: 91, Issue:5-6

    Topics: Anticonvulsants; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Intellectual Disability; Lennox Gastaut Syndrome; Male; Spasms, Infantile; Triazoles

2013
Rufinamide as an adjunctive therapy for Lennox-Gastaut syndrome: a randomized double-blind placebo-controlled trial in Japan.
    Epilepsy research, 2014, Volume: 108, Issue:9

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Double-Blind Method; Electroencephalography; Female; Follow-Up Studies; Humans; Japan; Lennox Gastaut Syndrome; Male; Statistics, Nonparametric; Treatment Outcome; Triazoles; Young Adult

2014
Safety and pharmacokinetic profile of rufinamide in pediatric patients aged less than 4 years with Lennox-Gastaut syndrome: An interim analysis from a multicenter, randomized, active-controlled, open-label study.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2016, Volume: 20, Issue:3

    Topics: Anticonvulsants; Child, Preschool; Female; Humans; Infant; Lennox Gastaut Syndrome; Male; Triazoles

2016
Long-term safety and seizure outcome in Japanese patients with Lennox-Gastaut syndrome receiving adjunctive rufinamide therapy: An open-label study following a randomized clinical trial.
    Epilepsy research, 2016, Volume: 121

    Topics: Anticonvulsants; Child; Child, Preschool; Double-Blind Method; Electrocardiography; Female; Humans; Japan; Lennox Gastaut Syndrome; Longitudinal Studies; Male; Time Factors; Treatment Outcome; Triazoles

2016
Rufinamide in children and adults with Lennox-Gastaut syndrome: first Italian multicenter experience.
    Seizure, 2010, Volume: 19, Issue:9

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Intellectual Disability; Italy; Lennox Gastaut Syndrome; Male; Spasms, Infantile; Treatment Outcome; Triazoles; Valproic Acid; Young Adult

2010
Rufinamide as an adjuvant treatment in children with Lennox-Gastaut syndrome.
    Seizure, 2012, Volume: 21, Issue:4

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Intellectual Disability; Lennox Gastaut Syndrome; Male; Spasms, Infantile; Triazoles

2012
Rufinamide efficacy and safety as adjunctive treatment in children with focal drug resistant epilepsy: the first Italian prospective study.
    Epilepsy research, 2012, Volume: 102, Issue:1-2

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Resistance; Drug Therapy, Combination; Epilepsies, Partial; Female; Follow-Up Studies; Humans; Intellectual Disability; Italy; Lennox Gastaut Syndrome; Male; Prospective Studies; Spasms, Infantile; Treatment Outcome; Triazoles; Young Adult

2012

Other Studies

14 other study(ies) available for triazoles and Lennox-Gastaut Syndrome

ArticleYear
Rufinamide efficacy and association with phenotype and genotype in children with intractable epilepsy: A retrospective single center study.
    Epilepsy research, 2020, Volume: 168

    Topics: Anticonvulsants; Child; Child, Preschool; Drug Resistant Epilepsy; Epilepsy; Female; Genotype; Humans; Infant; Lennox Gastaut Syndrome; Male; Phenotype; Retrospective Studies; Seizures; Triazoles

2020
Rufinamide as add-on therapy in children with epileptic encephalopathies other than Lennox-Gastaut syndrome: A study of 34 patients.
    Epilepsy & behavior : E&B, 2020, Volume: 108

    Topics: Adolescent; Anticonvulsants; Argentina; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Humans; Lennox Gastaut Syndrome; Male; Retrospective Studies; Seizures; Triazoles; Valproic Acid

2020
Cognitive, adaptive, and behavioral effects of adjunctive rufinamide in Lennox-Gastaut syndrome: A prospective observational clinical study.
    Epilepsy & behavior : E&B, 2020, Volume: 112

    Topics: Adolescent; Adult; Anticonvulsants; Child; Cognition; Humans; Lennox Gastaut Syndrome; Middle Aged; Prospective Studies; Triazoles; Young Adult

2020
How Can an Na
    Annals of neurology, 2021, Volume: 89, Issue:6

    Topics: Animals; Female; Lennox Gastaut Syndrome; Male; Mice; Mice, Inbred C57BL; Neurons; Seizures; Triazoles; Voltage-Gated Sodium Channel Blockers

2021
Short-term efficacy and safety of rufinamide for Lennox-Gastaut syndrome.
    No to hattatsu = Brain and development, 2016, Volume: 48, Issue:5

    Topics: Anticonvulsants; Child; Female; Humans; Lennox Gastaut Syndrome; Male; Pedigree; Triazoles

2016
Three children with Lennox-Gastaut syndrome presenting long-term good seizure outcome under rufinamide treatment.
    No to hattatsu = Brain and development, 2017, Volume: 49, Issue:1

    Topics: Anticonvulsants; Child; Child, Preschool; Female; Humans; Infant; Lennox Gastaut Syndrome; Male; Seizures; Time Factors; Treatment Outcome; Triazoles

2017
Rufinamide efficacy and safety in children aged 1-4 years with Lennox-Gastaut syndrome.
    Brain & development, 2018, Volume: 40, Issue:10

    Topics: Adjuvants, Pharmaceutic; Anticonvulsants; Child, Preschool; Female; Humans; Infant; Lennox Gastaut Syndrome; Male; Outcome Assessment, Health Care; Retrospective Studies; Triazoles

2018
Evaluation of WO2014121383 A1: a process for preparation of rufinamide and intermediates.
    Expert opinion on therapeutic patents, 2019, Volume: 29, Issue:1

    Topics: Animals; Anticonvulsants; Child; Humans; Lennox Gastaut Syndrome; Patents as Topic; Triazoles

2019
Short-term efficacy and tolerability of rufinamide adjunctive therapy in children with refractory generalised epilepsy.
    Epileptic disorders : international epilepsy journal with videotape, 2013, Volume: 15, Issue:1

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsies, Myoclonic; Epilepsy, Generalized; Female; Humans; Intellectual Disability; Lennox Gastaut Syndrome; Male; Spasms, Infantile; Treatment Outcome; Triazoles

2013
Retention rates of rufinamide in pediatric epilepsy patients with and without Lennox-Gastaut Syndrome.
    Epilepsy research, 2015, Volume: 112

    Topics: Adolescent; Anticonvulsants; Child; Cohort Studies; Epilepsy; Female; Humans; Kaplan-Meier Estimate; Lennox Gastaut Syndrome; Male; Treatment Outcome; Triazoles

2015
Rufinamide in children and adults in routine clinical practice.
    Acta neurologica Scandinavica, 2017, Volume: 135, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Child; Epilepsy, Generalized; Female; Humans; Lennox Gastaut Syndrome; Male; Middle Aged; Seizures; Triazoles; Vomiting; Weight Loss

2017
Serum concentrations of rufinamide in children and adults with epilepsy: the influence of dose, age, and comedication.
    Therapeutic drug monitoring, 2011, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Body Weight; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Intellectual Disability; Lennox Gastaut Syndrome; Male; Middle Aged; Seizures; Spasms, Infantile; Triazoles; Valproic Acid; Young Adult

2011
Drug-induced QT-interval shortening following antiepileptic treatment with oral rufinamide.
    Heart rhythm, 2012, Volume: 9, Issue:5

    Topics: Administration, Oral; Adult; Aged; Anticonvulsants; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Electrocardiography; Epilepsy; Female; Follow-Up Studies; Humans; Intellectual Disability; Lennox Gastaut Syndrome; Male; Middle Aged; Spasms, Infantile; Triazoles; Young Adult

2012
Effectiveness and tolerability of rufinamide in children and young adults with Lennox-Gastaut syndrome: a single center study in Korea.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:7

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Female; Humans; Intellectual Disability; Lennox Gastaut Syndrome; Male; Neurosurgical Procedures; Republic of Korea; Retrospective Studies; Seizures; Spasms, Infantile; Treatment Outcome; Triazoles; Young Adult

2013