triazoles has been researched along with Invasiveness, Neoplasm in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (6.56) | 18.2507 |
| 2000's | 12 (19.67) | 29.6817 |
| 2010's | 42 (68.85) | 24.3611 |
| 2020's | 3 (4.92) | 2.80 |
| Authors | Studies |
|---|---|
| Bernards, R; Caldas, C; Chin, SF; Crown, JP; Das, S; Di Grande, A; Dowling, CM; Fan, Y; Gallagher, WM; Haley, KE; Jirström, K; Linn, S; Madden, SF; Mooney, B; Moran, B; Ní Chonghaile, T; O'Connor, DP; Rueda, OM; Tarrant, F; Varešlija, D; Walsh, L; Young, LS | 1 |
| Adrian, TE; Albawardi, A; Almarzooqi, S; Haneefa, S; Hennig, R; Imbaraj, E; Maruta, H; Nemmar, A; Subramanya, S; Zaaba, NE | 1 |
| Kao, CY; Tsai, MJ; Tsai, SY; Wang, L; Xu, M | 1 |
| An, H; Heo, JS; Hong, CP; Hong, E; Kang, JM; Kim, SJ; Lee, S; Ooshima, A; Park, J; Park, JO; Park, S; Park, SH | 1 |
| Agata, Y; Kageyama, S; Kawamoto, H; Kawauchi, A; Kondo, K; Miyazaki, K; Miyazaki, M; Motooka, D; Nagasawa, M; Okuzaki, D; Terada, K; Tomimatsu, K; Yoshida, T | 1 |
| Cheng, SY; Copland, JA; Enomoto, K; Meltzer, P; Park, S; Qi, J; Willingham, MC; Zhao, L; Zhu, X; Zhu, YJ | 1 |
| Li, Z; Wang, C; Wang, L; Wang, R; Wu, X; Yang, C; Yang, P; Zhang, F | 1 |
| Dai, C; Fu, Z; Han, B; Jia, X; Li, W; Ma, J; Qian, Y; Ruan, H; Tong, H; Wang, Y; Wen, J; Xu, J; Zhou, C | 1 |
| Asano, Y; Goto, W; Hatano, T; Hirakawa, K; Kashiwagi, S; Motomura, H; Noda, S; Ohira, M; Onoda, N; Takada, K; Takashima, T; Tsujio, G | 1 |
| Alomary, M; Antony, J; Cunnea, P; Fotopoulou, C; Gabra, H; Huang, RY; Jung, Y; Karali, E; Kelly, Z; Mills, GB; Nixon, K; Paterson, A; Recchi, C; Roy-Nawathe, S; Tan, TZ; Thiery, JP; Zanini, E | 1 |
| Chen, Y; Guo, W; He, Y; Krimm, I; Li, Y; Liu, M; Mi, D; Pei, H; Shao, T; Wang, P; Wang, X; Yi, Z; Zhang, Y | 1 |
| Guo, JW; Huang, LH; Huang, MJ; Liu, HM; Wu, ZH; You, YZ; Zhao, JW | 1 |
| Bratton, MR; Carriere, PP; Llopis, SD; Preyan, LC; Skripnikova, E; Tilghman, SL; Townley, I; Wang, G; Williams, CC; Zhang, Q; Zhong, Q; Zou, J | 1 |
| Hamilton, J; Kamiya-Matsuoka, C; Kumar, VA; Kurzrock, R; Langford, LA; Moulder, S; Munoz, J; Pasche, LJ; Taggart, MW; Tummala, S | 1 |
| Chaturvedi, P; Gilkes, DM; Hu, H; Liang, H; Luo, W; Semenza, GL; Takano, N; Xiang, L | 1 |
| Nakamura, H; Yoneyama, K | 1 |
| Chai, J; Chen, D; Cheng, X; Jia, S; Li, T; Liang, L; Shen, Z; Sun, M; Yang, X | 1 |
| Olin, JL; St Pierre, M | 1 |
| Cheng, JC; Chiu, KC; Chou, YT; Huang, RY; Lee, CH; Liu, SY; Shieh, YS; Yeh, CT; Yuh, DY | 1 |
| Bansal, N; Bertino, JR; DiPaola, RS; Mishra, PJ; Stein, M | 1 |
| Dietl, O; Muehlenberg, K; Pech, O; Piso, P | 1 |
| Ali Alharbi, S; Ananda, H; Baburajeev, CP; Bender, A; Chinnathambi, A; Dhananjaya Mohan, C; Fuchs, JE; Girish, KS; Jagadish, S; Li, F; Rangappa, KS; Rangappa, S; Sethi, G; Sivaraman Siveen, K; Zayed, ME; Zhang, J | 1 |
| Cavanaugh, A; Danella, JF; Juengst, B; Sheridan, K; Williams, H | 1 |
| Boughey, JC; Chow, HH; Frank, D; Hsu, CH; Lang, JE; Ley, M; López, AM; Perloff, M; Pruthi, S; Taverna, JA | 1 |
| Kim, J; Oktay, K; Turan, V | 1 |
| Allred, JB; Goetz, MP; Ingle, JN; Moreno-Aspitia, A; Northfelt, DW; Perez, EA; Tan, WW | 1 |
| Furukawa, S; Handa, H; Hashimoto, A; Hashimoto, S; Mikami, S; Oikawa, T; Okada, Y; Onodera, Y; Oya, M; Sabe, H; Sugino, H; Yoshikawa, A | 1 |
| Benner, A; Berthel, A; Brand, K; Buechler, MW; Falk, CS; Grabe, N; Halama, N; Herrmann, T; Jaeger, D; Kahlert, C; Klupp, F; Koch, M; Krauss, J; Kunz, C; Lasitschka, F; Lerchl, T; Luckner-Minden, C; Luecke, S; Schneider, M; Springfeld, C; Suarez-Carmona, M; Suetterlin, T; Ulrich, A; Weitz, J; Zitvogel, L; Zoernig, I | 1 |
| Blee, AM; Huang, H; Liu, S; Wang, L | 1 |
| Bózsity, N; Mernyák, E; Minorics, R; Ocsovszki, I; Schneider, G; Szabó, J; Wang, HC; Wölfling, J; Wu, CC; Zupkó, I | 1 |
| Fujiwara, T; Nishitani, S; Noma, K; Ohara, T; Shirakawa, Y; Tazawa, H; Tomono, Y; Watanabe, S | 1 |
| Huang, P; Lv, Z; Qi, Y; Wang, L; Wei, X; Wu, X; Yang, P; Zhang, F | 1 |
| Andreucci, E; Chiarugi, P; Fearns, A; Francica, P; Isacke, CM; Martin, LA; Morandi, A | 1 |
| Athota, VR; Day, CJ; Elsworth, B; Freeman, R; Gasch, C; Mellick, AS; Mittal, V; Nikolic, I; Pouliot, N; Rasighaemi, P; Rogers, K; Sax, MJ; Swarbrick, A; Wei, M; Westcott, DE | 1 |
| Klinge, CM; Muluhngwi, P | 1 |
| Bagante, F; Connolly, R; Pawlik, TM; Spolverato, G; Vitale, A | 1 |
| Alcaro, S; Botta, G; Botta, M; Brullo, C; Celano, M; Cosco, D; Ferretti, E; Filetti, S; Fresta, M; Navarra, M; Puxeddu, E; Racanicchi, L; Russo, D; Schenone, S; Varano, E | 1 |
| Dieras, V; Florance, A; Gomez, HL; Johnston, S; Kennedy, MJ; Lichinitser, M; Maltzman, J; Manikhas, A; O'Rourke, L; Oliva, C; Pegram, M; Pippen, J; Pivot, X; Press, MF; Romieu, G; Sadeghi, S; Stein, S | 1 |
| Brodie, A; Chen, S; Fischgräbe, J; Götte, M; Kiesel, L; Macedo, LF; Radke, I; Smollich, M; Wülfing, P | 1 |
| Apatira, A; Brandt, R; Chang, B; Chua, J; Ding, P; Duan, M; Franci, C; Goff, D; Heckrodt, TJ; Hitoshi, Y; Holland, SJ; Hu, Y; Li, W; Pan, A; Payan, DG; Pine, P; Singh, R; Torneros, A; Yu, J; Zhang, J | 1 |
| Jung, SY; Kang, HS; Kim, EA; Kim, SW; Kwon, Y; Lee, KS; Lee, S; Nam, BH; Park, IH; Ro, J | 1 |
| Arron, ST; Ibrahim, SF; Singer, JP | 1 |
| Alciato, F; Anichini, A; Avanzi, G; Bersani, I; Canevari, S; Castellano, G; Catani, M; De Santis, G; Nicolini, G; Sensi, M; Tomassetti, A; Tragni, G | 1 |
| Jin, CH; Kim, DK; Nam, JS; Park, CY; Sheen, YY; Son, JY | 1 |
| Cruz Jurado, J; Fernández Martínez, R; Galve Calvo, E; García Mata, J; García Palomo, A; Murillo Jaso, L; Peláez Fernández, I; Polo Marqués, E; Richart Aznar, P; Sampedro Gimeno, T | 1 |
| Anesini, C; Avanzo, RE; D'Accorso, NB; Errea, MI; Fascio, ML | 1 |
| Aucagne, V; Delmas, AF; Lalmanach, G; Lecaille, F; Valverde, IE | 1 |
| Christopoulos, S; Rivera, JA; Small, D; Trifiro, M | 1 |
| Miller, DS; Rao, GG | 1 |
| Ejlertsen, B; Joensuu, H; Lønning, PE; Rutqvist, LE | 1 |
| Katsumine, Y; Noda, N; Osawa, I; Uehara, S; Yuasa, H | 1 |
| Attoub, S; Bruyneel, E; Emami, S; Gespach, C; Grijelmo, C; Nguyen, QD; Rivat, C; Rodrigue, CM; Rodrigues, S | 1 |
| Bryce, C; Chia, SK; Gelmon, KA; Kennecke, HF; Norris, B; Olivotto, IA; Speers, C | 1 |
| Calorini, L; Fallani, A; Gabellieri, S; Mannini, A; Mugnai, G; Ruggieri, S | 1 |
| Fabré, G; Maes, B; Peetermans, WE; Van Dorpe, J; Vanacker, A | 1 |
| Adams, JE; Beckmann, MW; Clack, G; Coleman, RE; Cuzick, J; Eastell, R; Hannon, RA; Howell, A; Mackey, JR | 1 |
| Friedlander, ML; Kohn, EC; Qu, XJ; Yang, JL; Yu, Y | 1 |
| Blackmore, PF; Kohn, EC; Palad, AJ; Rhim, JS; Schellhammer, PF; Somers, KD; Wasilenko, WJ; Wright, GL | 1 |
| Jacobs, W; Kohn, EC; Mikkelsen, T; Nelson, K; Rosenblum, ML; Smith, R | 1 |
| Kohn, EC; Lambert, PA; Perry, RR; Somers, KD | 1 |
| Blackmore, PF; Kohn, EC; Palad, AJ; Pincus, WA; Schechter, GL; Somers, KD; Spoonster, JR; Wasilenko, WJ; Wu, Y | 1 |
6 review(s) available for triazoles and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Aromatase inhibitors in breast cancer prevention.
Topics: Anastrozole; Androstadienes; Anticarcinogenic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Neoplasm Invasiveness; Nitriles; Postmenopause; Risk; Triazoles | 2014 |
Identification of miRNAs as biomarkers for acquired endocrine resistance in breast cancer.
Topics: Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Exosomes; Female; Gene Expression Regulation, Neoplastic; Humans; Letrozole; MicroRNAs; Neoplasm Invasiveness; Neoplasm Metastasis; Nitriles; Signal Transduction; Tamoxifen; Triazoles | 2017 |
Management of patients with metastatic breast cancer.
Topics: Adult; Age Factors; Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Disease Management; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Delivery Systems; Estradiol; Female; Fulvestrant; Humans; Letrozole; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Nitriles; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Survival Analysis; Treatment Outcome; Triazoles | 2011 |
Hormonal manipulation of benign metastasizing leiomyomas: report of two cases and review of the literature.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Brachial Plexus Neuropathies; Enzyme Inhibitors; Estrogen Receptor Modulators; Female; Gonadotropin-Releasing Hormone; Humans; Leiomyoma; Lung Neoplasms; Magnetic Resonance Imaging; Middle Aged; Neoplasm Invasiveness; Neoplasms; Nitriles; Radiography, Thoracic; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Triazoles; Uterine Neoplasms | 2004 |
Clinical applications of hormonal therapy in ovarian cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Clinical Trials, Phase II as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leuprolide; Medroxyprogesterone; Neoplasm Invasiveness; Neoplasm Staging; Nitriles; Ovarian Neoplasms; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
Aromatase inhibitors in the treatment of early and advanced breast cancer.
Topics: Adult; Aged; Anastrozole; Aromatase Inhibitors; Biopsy, Needle; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Immunohistochemistry; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Nitriles; Postmenopause; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Survival Rate; Treatment Outcome; Triazoles | 2005 |
5 trial(s) available for triazoles and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Double-Blind, Randomized Trial of Alternative Letrozole Dosing Regimens in Postmenopausal Women with Increased Breast Cancer Risk.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Lobular; Double-Blind Method; Female; Follow-Up Studies; Humans; Letrozole; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Nitriles; Postmenopause; Prognosis; Triazoles | 2016 |
Phase I Study of Panobinostat (LBH589) and Letrozole in Postmenopausal Metastatic Breast Cancer Patients.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hydroxamic Acids; Immunoenzyme Techniques; Indoles; Letrozole; Lymphatic Metastasis; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Nitriles; Panobinostat; Postmenopause; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; Triazoles | 2016 |
Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Carcinoma; Disease-Free Survival; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Lapatinib; Letrozole; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Nitriles; Postmenopause; Prognosis; Proportional Hazards Models; Quinazolines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Risk Assessment; Survival Analysis; Treatment Outcome; Triazoles | 2009 |
Phase II parallel group study showing comparable efficacy between premenopausal metastatic breast cancer patients treated with letrozole plus goserelin and postmenopausal patients treated with letrozole alone as first-line hormone therapy.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Bone Density; Breast Neoplasms; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Goserelin; Humans; Immunohistochemistry; Injections, Subcutaneous; Kaplan-Meier Estimate; Letrozole; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Staging; Nitriles; Postmenopause; Premenopause; Probability; Prognosis; Proportional Hazards Models; Risk Assessment; Statistics, Nonparametric; Survival Analysis; Treatment Outcome; Triazoles | 2010 |
Effect of anastrozole on bone mineral density: 5-year results from the anastrozole, tamoxifen, alone or in combination trial 18233230.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Bone Density; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Female; Humans; Neoplasm Invasiveness; Nitriles; Postmenopause; Prospective Studies; Tamoxifen; Treatment Outcome; Triazoles | 2008 |
50 other study(ies) available for triazoles and Invasiveness, Neoplasm
| Article | Year |
|---|---|
BET Inhibition as a Rational Therapeutic Strategy for Invasive Lobular Breast Cancer.
Topics: Aniline Compounds; Antineoplastic Agents; Apoptosis; Azepines; Breast Neoplasms; Carcinoma, Lobular; Cell Cycle; Cell Proliferation; Cohort Studies; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Invasiveness; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Sulfonamides; Survival Rate; Transcription Factors; Triazoles; Tumor Cells, Cultured | 2019 |
1,2,3-Triazolyl ester of ketorolac (15K), a potent PAK1 blocker, inhibits both growth and metastasis of orthotopic human pancreatic cancer xenografts in mice.
Topics: Animals; Body Weight; Cell Line, Tumor; Cell Proliferation; Esters; Hemodynamics; Humans; Inhibitory Concentration 50; Ketorolac; Mice; Mice, Nude; Neoplasm Invasiveness; Triazoles; Xenograft Model Antitumor Assays | 2019 |
Small molecule JQ1 promotes prostate cancer invasion via BET-independent inactivation of FOXA1.
Topics: Animals; Azepines; Epithelial-Mesenchymal Transition; Hepatocyte Nuclear Factor 3-alpha; Humans; Male; Mice; Mice, SCID; Neoplasm Invasiveness; Neoplasm Proteins; PC-3 Cells; Prostatic Neoplasms; Proteins; Triazoles; Xenograft Model Antitumor Assays | 2020 |
Inhibition of TGF-β signalling in combination with nal-IRI plus 5-Fluorouracil/Leucovorin suppresses invasion and prolongs survival in pancreatic tumour mouse models.
Topics: Aniline Compounds; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogenesis; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Drug Synergism; Epithelial-Mesenchymal Transition; Fluorouracil; Gene Expression Regulation, Neoplastic; Irinotecan; Leucovorin; Liposomes; Mice, Inbred C57BL; Nanoparticles; Neoplasm Invasiveness; Pancreatic Neoplasms; Signal Transduction; Survival Analysis; Transcriptome; Transforming Growth Factor beta; Triazoles; Tumor Stem Cell Assay; Up-Regulation | 2020 |
Long non-coding RNA MANCR is a target of BET bromodomain protein BRD4 and plays a critical role in cellular migration and invasion abilities of prostate cancer.
Topics: Azepines; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Down-Regulation; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasm Invasiveness; Prostatic Neoplasms; RNA, Untranslated; Transcription Factors; Triazoles | 2020 |
Targeting MYC as a Therapeutic Intervention for Anaplastic Thyroid Cancer.
Topics: Animals; Antineoplastic Agents; Azepines; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Mice, Nude; Molecular Targeted Therapy; Neoplasm Invasiveness; Proto-Oncogene Proteins c-myc; Thyroid Carcinoma, Anaplastic; Triazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2017 |
BRD4 inhibition suppresses cell growth, migration and invasion of salivary adenoid cystic carcinoma.
Topics: Azepines; Carcinoma, Adenoid Cystic; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Humans; Neoplasm Invasiveness; Nuclear Proteins; Real-Time Polymerase Chain Reaction; Salivary Gland Neoplasms; Transcription Factors; Triazoles | 2017 |
Benzotriazole Enhances Cell Invasive Potency in Endometrial Carcinoma Through CTBP1-Mediated Epithelial-Mesenchymal Transition.
Topics: Alcohol Oxidoreductases; Carcinogens, Environmental; Cell Line, Tumor; Cell Movement; DNA-Binding Proteins; Endometrial Neoplasms; Endometrium; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Invasiveness; Triazoles | 2017 |
[A Case of Breast Cancer with Local Recurrence in the Reconstructed Breast Tissue].
Topics: Adult; Anastrozole; Breast Neoplasms; Female; Gonadotropin-Releasing Hormone; Hormone Replacement Therapy; Humans; Mammaplasty; Mastectomy; Multimodal Imaging; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Nitriles; Treatment Outcome; Triazoles | 2017 |
The tumour suppressor OPCML promotes AXL inactivation by the phosphatase PTPRG in ovarian cancer.
Topics: Animals; Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; Cell Survival; Chickens; Cholesterol; Enzyme Activation; Epithelial Cells; Fallopian Tubes; Female; Gene Silencing; GPI-Linked Proteins; Humans; Intercellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Membrane Microdomains; Neoplasm Invasiveness; Ovarian Neoplasms; Phosphorylation; Protein Binding; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptor-Like Protein Tyrosine Phosphatases, Class 5; Treatment Outcome; Triazoles; Tumor Suppressor Proteins | 2018 |
Modification and Biological Evaluation of a Series of 1,5-Diaryl-1,2,4-triazole Compounds as Novel Agents against Pancreatic Cancer Metastasis through Targeting Myoferlin.
Topics: Animals; Antineoplastic Agents; Calcium-Binding Proteins; Cell Line, Tumor; Cell Movement; Drug Design; Epithelial-Mesenchymal Transition; Humans; Membrane Proteins; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; Muscle Proteins; Neoplasm Invasiveness; Neoplasm Metastasis; Pancreatic Neoplasms; Structure-Activity Relationship; Triazoles; Xenograft Model Antitumor Assays | 2019 |
Design, synthesis and biological evaluation of new steroidal β-triazoly enones as potent antiproliferative agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Ketones; Molecular Structure; Neoplasm Invasiveness; Steroids; Structure-Activity Relationship; Triazoles | 2019 |
Proteomic signatures of acquired letrozole resistance in breast cancer: suppressed estrogen signaling and increased cell motility and invasiveness.
Topics: Actin Cytoskeleton; Amides; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Shape; Drug Resistance, Neoplasm; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Letrozole; Mesoderm; Neoplasm Invasiveness; Neoplasm Proteins; Nitriles; Protein Kinase Inhibitors; Proteomics; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Triazoles; Vimentin | 2013 |
Posterior reversible encephalopathy syndrome: more than meets the eye.
Topics: Anastrozole; Biopsy, Needle; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease Progression; Electroencephalography; Fatal Outcome; Female; Humans; Immunohistochemistry; Magnetic Resonance Imaging; Mastectomy; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Neoplasms, Multiple Primary; Nitriles; Posterior Leukoencephalopathy Syndrome; Risk Assessment; Triazoles | 2013 |
Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer.
Topics: Animals; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; HSP90 Heat-Shock Proteins; Humans; Hypoxia-Inducible Factor 1; Immunoblotting; Immunohistochemistry; Mice; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplastic Stem Cells; Neovascularization, Pathologic; Neural Cell Adhesion Molecule L1; Reverse Transcriptase Polymerase Chain Reaction; Triazoles; Triple Negative Breast Neoplasms; Tumor Burden; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2014 |
[An elderly patient with advanced breast cancer who responded to treatment with letrozole-a case report].
Topics: Aged, 80 and over; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Humans; Letrozole; Neoplasm Invasiveness; Neoplasm Metastasis; Nitriles; Triazoles | 2013 |
The CCL5/CCR5 axis contributes to the perineural invasion of human salivary adenoid cystic carcinoma.
Topics: Carcinoma, Adenoid Cystic; CCR5 Receptor Antagonists; Cell Line, Tumor; Cell Movement; Chemokine CCL5; Cyclohexanes; Humans; Maraviroc; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Recurrence, Local; Peripheral Nerves; Receptors, CCR5; Salivary Gland Neoplasms; Triazoles | 2014 |
Protumoral effect of macrophage through Axl activation on mucoepidermoid carcinoma.
Topics: Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Carcinoma, Mucoepidermoid; Cell Culture Techniques; Cell Line; Cell Line, Tumor; Cell Movement; Coculture Techniques; Disease Progression; Enzyme Activation; Humans; Macrophage Activation; Macrophages; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Signal Transduction; Triazoles | 2014 |
Axl receptor tyrosine kinase is up-regulated in metformin resistant prostate cancer cells.
Topics: Adenylate Kinase; Antineoplastic Agents; Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin D1; Docetaxel; Drug Resistance, Neoplasm; Enzyme Activation; Epithelial-Mesenchymal Transition; Gene Knockdown Techniques; Humans; Male; Metformin; Neoplasm Invasiveness; Prostatic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor Protein-Tyrosine Kinases; Taxoids; Triazoles; Up-Regulation | 2015 |
[Multiple smooth colon stenosis in 76-year-old female patient].
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Diagnosis, Differential; Female; Humans; Intestinal Obstruction; Letrozole; Neoplasm Invasiveness; Nitriles; Treatment Outcome; Triazoles | 2015 |
Development of Novel Triazolo-Thiadiazoles from Heterogeneous "Green" Catalysis as Protein Tyrosine Phosphatase 1B Inhibitors.
Topics: Animals; Antineoplastic Agents; Benzofurans; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Cell Movement; Chromones; Cyclin D1; Disease Models, Animal; Dose-Response Relationship, Drug; Female; G1 Phase Cell Cycle Checkpoints; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Inhibitor of Apoptosis Proteins; Liver Neoplasms; Mice; Models, Molecular; Neoplasm Invasiveness; Neovascularization, Pathologic; Poly(ADP-ribose) Polymerases; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; STAT3 Transcription Factor; Structure-Activity Relationship; Survivin; Thiadiazoles; Triazoles | 2015 |
Combined inhibition of heat shock proteins 90 and 70 leads to simultaneous degradation of the oncogenic signaling proteins involved in muscle invasive bladder cancer.
Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug Synergism; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Muscles; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins; Purine Nucleosides; Retinoblastoma Protein; Signal Transduction; Triazoles; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms | 2015 |
Long-Term Safety of Letrozole and Gonadotropin Stimulation for Fertility Preservation in Women With Breast Cancer.
Topics: Adult; Aromatase Inhibitors; Breast Neoplasms; Case-Control Studies; Drug Therapy, Combination; Female; Fertility; Fertility Preservation; Gonadotropins; Humans; Letrozole; Neoplasm Grading; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Nitriles; Ovulation Induction; Prospective Studies; Survival Rate; Treatment Outcome; Triazoles | 2016 |
Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer.
Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Adult; Aged; Aged, 80 and over; Amides; Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Female; GTP-Binding Protein alpha Subunits, G12-G13; Guanine Nucleotide Exchange Factors; HEK293 Cells; Humans; Immunohistochemistry; Indoles; Isoxazoles; Kidney Neoplasms; Lysophospholipids; Male; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Nerve Tissue Proteins; Propionates; Pyridines; Pyrroles; Receptors, Lysophosphatidic Acid; Signal Transduction; Sirolimus; Sunitinib; Triazoles | 2016 |
Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients.
Topics: Adenocarcinoma; Apoptosis; Chemokine CCL5; Chemokines; Chemotaxis; Clinical Trials, Phase I as Topic; Clodronic Acid; Colorectal Neoplasms; Cyclohexanes; Humans; Interferon-alpha; Liver Neoplasms; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Macrophages; Maraviroc; Molecular Targeted Therapy; Neoplasm Invasiveness; Neoplasm Proteins; NG-Nitroarginine Methyl Ester; Phenylurea Compounds; Pilot Projects; Pyridines; Receptors, CCR5; STAT3 Transcription Factor; Survival Analysis; Triazoles; Tumor Cells, Cultured; Tumor Microenvironment | 2016 |
BET bromodomain-mediated interaction between ERG and BRD4 promotes prostate cancer cell invasion.
Topics: Azepines; Base Sequence; Benzodiazepines; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; HEK293 Cells; Humans; Male; Neoplasm Invasiveness; Nuclear Proteins; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Proteins; Transcription Factors; Transcriptional Regulator ERG; Triazoles | 2016 |
Mechanism of antiproliferative action of a new d-secoestrone-triazole derivative in cervical cancer cells and its effect on cancer cell motility.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Estrogen Receptor Modulators; Estrone; Female; Flow Cytometry; HeLa Cells; Human papillomavirus 16; Humans; Necrosis; Neoplasm Invasiveness; Prognosis; Triazoles; Tubulin; Uterine Cervical Neoplasms | 2017 |
Iron depletion-induced downregulation of N-cadherin expression inhibits invasive malignant phenotypes in human esophageal cancer.
Topics: Animals; Benzoates; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Deferasirox; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Iron Deficiencies; Mice; Neoplasm Invasiveness; Neoplasm Transplantation; Phenotype; Triazoles | 2016 |
JQ1, a small molecule inhibitor of BRD4, suppresses cell growth and invasion in oral squamous cell carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Azepines; Blotting, Western; Carcinoma, Squamous Cell; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Fluorescent Antibody Technique; Head and Neck Neoplasms; Humans; Mouth Neoplasms; Neoplasm Invasiveness; Nuclear Proteins; Polymerase Chain Reaction; Squamous Cell Carcinoma of Head and Neck; Transcription Factors; Triazoles | 2016 |
Targeting the receptor tyrosine kinase RET in combination with aromatase inhibitors in ER positive breast cancer xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Carbanilides; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Humans; Letrozole; MCF-7 Cells; Mice, Nude; Molecular Targeted Therapy; Neoplasm Invasiveness; Nitriles; Ovariectomy; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-ret; Receptors, Estrogen; Signal Transduction; Spheroids, Cellular; Time Factors; Transfection; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays | 2016 |
Cancer cell CCL5 mediates bone marrow independent angiogenesis in breast cancer.
Topics: Angiogenesis Inhibitors; Animals; Breast Neoplasms; CCR5 Receptor Antagonists; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemokine CCL5; Culture Media, Conditioned; Cyclohexanes; Endothelial Cells; Female; Humans; Maraviroc; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Grading; Neoplasm Invasiveness; Neovascularization, Pathologic; Paracrine Communication; Proto-Oncogene Proteins c-akt; Receptors, CCR5; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases; Triazoles; Tumor Burden; Tumor Microenvironment | 2016 |
Liver Resection for Breast Cancer Liver Metastases: A Cost-utility Analysis.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Disease-Free Survival; Docetaxel; Female; Hepatectomy; Humans; Letrozole; Liver Neoplasms; Male; Markov Chains; Neoplasm Invasiveness; Neoplasm Staging; Nitriles; Piperazines; Pyridines; Quality-Adjusted Life Years; Survival Rate; Taxoids; Triazoles | 2017 |
Cytotoxic effects of a novel pyrazolopyrimidine derivative entrapped in liposomes in anaplastic thyroid cancer cells in vitro and in xenograft tumors in vivo.
Topics: Animals; Annexin A5; Apoptosis; Cell Division; Cell Line, Tumor; Humans; In Vitro Techniques; Liposomes; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Pyrazoles; Pyrimidines; STAT1 Transcription Factor; Thyroid Neoplasms; Triazoles; Xenograft Model Antitumor Assays | 2008 |
ETAR antagonist ZD4054 exhibits additive effects with aromatase inhibitors and fulvestrant in breast cancer therapy, and improves in vivo efficacy of anastrozole.
Topics: Anastrozole; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin-1; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Neoplasm Invasiveness; Nitriles; Pyrrolidines; Receptor, Endothelin A; Tamoxifen; Time Factors; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays | 2010 |
R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer.
Topics: Animals; Antineoplastic Agents; Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Breast Neoplasms; Carcinoma; Female; HeLa Cells; Humans; K562 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Oncogene Proteins; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Survival Analysis; Triazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2010 |
Catastrophic squamous cell carcinoma in lung transplant patients treated with voriconazole.
Topics: Antifungal Agents; Carcinoma, Squamous Cell; Fatal Outcome; Female; Heart Transplantation; Humans; Lung Transplantation; Middle Aged; Mycoses; Neoplasm Invasiveness; Neoplasm Metastasis; Pyrimidines; Skin Neoplasms; Triazoles; Voriconazole | 2010 |
Human cutaneous melanomas lacking MITF and melanocyte differentiation antigens express a functional Axl receptor kinase.
Topics: Antigens, Differentiation; Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Gene Knockdown Techniques; Humans; Melanoma; Melanoma-Specific Antigens; Microphthalmia-Associated Transcription Factor; Mutation; Neoplasm Invasiveness; Proto-Oncogene Proteins; Proto-Oncogene Proteins B-raf; Receptor Protein-Tyrosine Kinases; Skin Neoplasms; Triazoles | 2011 |
EW-7195, a novel inhibitor of ALK5 kinase inhibits EMT and breast cancer metastasis to lung.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Epithelial-Mesenchymal Transition; Female; Hep G2 Cells; Humans; Luciferases; Lung Neoplasms; Mice; Mice, Transgenic; Neoplasm Invasiveness; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Smad2 Protein; Triazoles | 2011 |
1,2,4-Triazole D-ribose derivatives: design, synthesis and antitumoral evaluation.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Ribose; Triazoles | 2012 |
Synthesis of a biologically active triazole-containing analogue of cystatin A through successive peptidomimetic alkyne-azide ligations.
Topics: Alkynes; Amino Acid Sequence; Azides; Cathepsins; Cell Line, Tumor; Click Chemistry; Cyclization; Cystatin A; Humans; Molecular Sequence Data; Neoplasm Invasiveness; Peptidomimetics; Triazoles | 2012 |
[Three cases of advanced breast cancer successfully treated with a weekly dose of paclitaxel].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Mastectomy, Modified Radical; Middle Aged; Neoplasm Invasiveness; Nitriles; Paclitaxel; Skin Neoplasms; Sternum; Triazoles | 2005 |
Inhibition of vascular endothelial growth factor (VEGF)-165 and semaphorin 3A-mediated cellular invasion and tumor growth by the VEGF signaling inhibitor ZD4190 in human colon cancer cells and xenografts.
Topics: Animals; Cisplatin; Colonic Neoplasms; Enzyme Inhibitors; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Piperidines; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Semaphorin-3A; Signal Transduction; Triazoles; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2006 |
Late risk of relapse and mortality among postmenopausal women with estrogen responsive early breast cancer after 5 years of tamoxifen.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; British Columbia; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Female; Humans; Letrozole; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Prognosis; Risk Factors; Survival Rate; Tamoxifen; Triazoles | 2007 |
Platelet-activating factor (PAF) is the effector of IFN gamma-stimulated invasiveness and motility in a B16 melanoma line.
Topics: Animals; Azepines; Cell Movement; Collagen; Culture Media, Conditioned; Drug Combinations; Interferon-gamma; Laminin; Melanoma; Mice; Neoplasm Invasiveness; Phenotype; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Proteoglycans; Receptors, G-Protein-Coupled; Stress Fibers; Time Factors; Triazoles; Tumor Cells, Cultured | 2006 |
Aggressive cutaneous squamous cell carcinoma associated with prolonged voriconazole therapy in a renal transplant patient.
Topics: Aged; Antifungal Agents; Aspergillosis; Carcinoma, Squamous Cell; Humans; Kidney Failure, Chronic; Kidney Transplantation; Lymphatic Metastasis; Male; Neoplasm Invasiveness; Postoperative Complications; Pyrimidines; Skin Neoplasms; Triazoles; Voriconazole | 2008 |
Selective sensitivity to carboxyamidotriazole by human tumor cell lines with DNA mismatch repair deficiency.
Topics: Antineoplastic Agents; Apoptosis; Calcium Channel Blockers; Cell Cycle; Cell Line, Tumor; Chromosomes, Human; Colonic Neoplasms; Colorimetry; DNA Mismatch Repair; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Male; Neoplasm Invasiveness; Neoplasms; Nifedipine; Ovarian Neoplasms; Prostatic Neoplasms; Transfection; Triazoles; Urinary Bladder Neoplasms | 2008 |
Effects of the calcium influx inhibitor carboxyamido-triazole on the proliferation and invasiveness of human prostate tumor cell lines.
Topics: Antineoplastic Agents; Calcium; Cell Division; Humans; Male; Neoplasm Invasiveness; Prostate-Specific Antigen; Prostatic Neoplasms; Triazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1996 |
Inhibitory effects of CAI in glioblastoma growth and invasion.
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Adhesion; Cell Division; Gelatinases; Glioblastoma; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Neoplasm Invasiveness; Triazoles; Tumor Cells, Cultured | 1997 |
Antiproliferative and antiinvasive effects of carboxyamido-triazole on breast cancer cell lines.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Calcium Channel Blockers; Cell Survival; Collagenases; Drug Screening Assays, Antitumor; Female; Gelatinases; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Metalloendopeptidases; Neoplasm Invasiveness; Receptors, Estrogen; Triazoles; Tumor Cells, Cultured | 1997 |
Inhibition of head and neck squamous cell carcinoma growth and invasion by the calcium influx inhibitor carboxyamido-triazole.
Topics: Antineoplastic Agents; Calcium; Calcium Channel Blockers; Carcinoma, Squamous Cell; Cell Division; Cell Movement; Head and Neck Neoplasms; Humans; Kinetics; Neoplasm Invasiveness; Signal Transduction; Triazoles; Tumor Cells, Cultured | 1997 |