triazoles has been researched along with Inflammation in 179 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (2.79) | 18.7374 |
| 1990's | 12 (6.70) | 18.2507 |
| 2000's | 22 (12.29) | 29.6817 |
| 2010's | 105 (58.66) | 24.3611 |
| 2020's | 35 (19.55) | 2.80 |
| Authors | Studies |
|---|---|
| Baraliakos, X; Barchuk, W; Besuyen, R; Gilles, L; Hendrikx, T; Landewé, R; Liu, K; Maksymowych, WP; Østergaard, M | 1 |
| Aslam, T; Basha, FZ; Choudhary, MI; Iqbal, S; Jahan, H; Khan, MA; Siddiqui, NN | 1 |
| An, N; Fan, X; Hua, T; Kong, E; Li, J; Li, Y; Song, H; Wang, H; Yuan, H | 1 |
| Chung, CH; Ha, KB; Jeong, AR; Kim, DK; Kim, HM; Kukongviriyapan, U; Lee, ES; Lee, EY; Sangartit, W; Shim, S | 1 |
| Dong, J; Gao, X; Liu, F; Wang, J; Zhao, P | 1 |
| Alfahad, N; Barnes, NM; Bennett, N; Capewell, N; Chu, CJ; Cowley, J; Denniston, AK; Dick, AD; Fernandez, A; Harrison, N; Hickman, E; Hill, LJ; Liu, X; Qureshi, OS; Thomas, CN; Vendrell, M | 1 |
| Bhattacharya, D; Buckley, D; Crowley, R; Duke, G; Friedman, SL; Kemble, G; Martins, EB; O'Farrell, M | 1 |
| Diao, J; Huang, S; Li, L; Meng, Z; Sun, W; Tian, S; Wang, Y; Yan, J; Yan, S; Zhou, Z; Zhu, W | 1 |
| da Silva, AR; de Carvalho da Silva, F; Faria, RX; Ferreira, VF; Fuly, AL; Gonzaga, DTG; Magalhães, BQ; Pacheco, PAF; Pereira, JS; Pinheiro, NG; Rodrigues, CR; Silva, AC; von Ranke, NL | 1 |
| Chen, H; Chu, M; Dong, J; Feng, H; Li, X; Pan, E; Qiang, J; Wu, X; Xu, B | 1 |
| Gu, Y; Liu, J; Zhou, Y | 1 |
| Grishina, M; Naumovich, V; Pathak, P; Potemkin, V; Shukla, PK; Verma, A | 1 |
| Chen, XG; Guo, SX; He, SJ; Li, L; Liu, SW; Nandakumar, KS; Tang, XD; Wan, YH; Wu, WY; Wu, XY; Yao, XG; Zou, M | 1 |
| Jia, M; Li, X; Liu, L; Meng, Z; Sun, W; Tian, S; Xi, Y; Yan, S; Zhou, Z; Zhu, W | 1 |
| Lappas, M; Lim, R; Nguyen-Ngo, C | 1 |
| Chen, W; Hong, J; Huang, D; Huang, Y; Kepler, CK; Li, S; Liang, A; Markova, DZ; Xu, K; Yan, J; Ye, W; Zhou, J | 1 |
| Cully, M | 1 |
| de Boer, P; de Kam, M; Drevets, W; Jacobs, G; Kanhai, K; Ravenstijn, P; Recourt, K; Siebenga, P; Timmers, M; van der Aart, J; van Gerven, J; van Nueten, L; Zuiker, R | 1 |
| Cheng, CY; Dege, N; Faizi, MSH; Haque, A; Hsieh, MF; Imran Hassan, S; Khan, MS | 1 |
| Singh, S | 1 |
| Bello, ML; Dos Santos, EG; Faria, RX; Rodrigues, CR | 1 |
| Buccioni, M; Coelho, JE; Dal Ben, D; Lambertucci, C; Lopes, LV; Marques-Morgado, I; Martí Navia, A; Marucci, G; Spinaci, A; Volpini, R | 1 |
| Chen, K; Huang, ZZ; Li, ZF; Liu, Y; Min, L | 1 |
| Dhillon, S; Keam, SJ | 1 |
| Bottino, C; Caretti, G; Filippakopoulos, P; Fittipaldi, R; Mamchaoui, K; Nevi, L; Segatto, M; Szokoll, R | 1 |
| Guo, YH; Huang, C; Ji, YR; Li, J; Li, Z; Shi, W; Sun, GP; Zhang, YL; Zheng, Y | 1 |
| Eleftheriou, P; Gavalas, A; Geronikaki, A; Haroun, M; Kamoutsis, C; Kochkar, H; Nair, AB; Paparisva, A; Petrou, A; Tratrat, C; Venugopala, KN | 1 |
| Costello, DA; Jones, AC; Pinki, F; Stewart, GS | 1 |
| Cribbs, AP; Feldmann, M; Filippakopoulos, P; Oerum, H; Oppermann, U; Penn, H; Philpott, M; Valge-Archer, V; Wells, G | 1 |
| An, GY; Baek, M; Chai, JC; Chai, YG; Choi, HI; Jung, KH; Lee, YS; Yoo, E | 1 |
| Huang, W; Huang, Y; Ma, L; Wang, R; Yang, G | 1 |
| Abdelall, EKA; Abdellatif, KRA; Elshemy, HAH; Hassanein, EHM; Kahk, NM; Philoppes, JN | 1 |
| Fearon, U; Flynn, K; Hanlon, MM; Marzaioli, V; O'Brien, A; Veale, DJ; Wade, SC | 1 |
| Duan, Y; Wang, Y | 1 |
| Fukaya, M; Hara, Y; Ito, A; Okamoto, H; Sakagami, H; Sugawara, T; Yamauchi, J | 1 |
| Fu, Y; Guo, LW; Li, J; Urabe, G; Zhao, L | 1 |
| Chakraborty, R; Jana, A; Jana, M; Mahata, D; Mandal, SM; Mondal, N; Mukherjee, A; Mukhopadhyay, CK; Nando, GB; Saha, T; Sen, S | 1 |
| Benko, E; Huibner, S; Kandel, G; Kaul, R; Kim, CJ; Kovacs, C; Ostrowski, M; Rousseau, R; Shahabi, K | 1 |
| Anand, P; Bradner, JE; Brown, JD; Duan, Q; Haldar, SM; Huang, Y; Lemieux, ME; McKinsey, TA; McMahon, S; Sahadevan, A; Salunga, HT; Shah, H; Srivastava, D; Thomas, S; Zhang, R | 1 |
| Hecker, M; Mayer, K; Morty, RE; Schaefer, CA; Schaefer, MB; Seeger, W; Witzenrath, M | 1 |
| Anastácio Furtado Pacheco, P; Arruda, JC; Bello, ML; Castro, HC; da Silva, FC; Dantas, LP; de Freitas, HR; de Melo Reis, RA; Faria, RX; Ferreira, LBG; Ferreira, VF; Gonzaga, DTG; Moreira Maramaldo Costa, TE; Penido, C; Rodrigues, CR; Sposito Simões, AP; von Ranke, NL | 1 |
| Donvito, G; Fox, TE; Hsu, KL; Kester, M; Lichtman, AH; Schurman, LD; Shin, M; Snyder, HW | 1 |
| Matharasala, G; Perumal, Y; Samala, G | 1 |
| Abdo, M; Fekry, E; Makary, S | 1 |
| Barat, C; Drouin, J; Leboeuf, M; Proust, A; Tremblay, MJ | 1 |
| Beitz, AJ; Choi, HS; Choi, SR; Lee, JH; Lee, MJ; Smeester, BA | 1 |
| Cortes-Salva, MY; Innis, RB; Jenko, KJ; Morse, CL; Pike, VW; Shrestha, S; Singh, P; Zoghbi, SS | 1 |
| Ayad, NG; Choi, JS; Lee, HE; Lee, JK; Rudman, MD; Tan, SK | 1 |
| Bernal-Chico, A; Brown, JM; Cipriani, R; Cravatt, BF; Hsu, KL; Manterola, A; Mato, S; Matute, C; Moreno-Rodríguez, M; Pérez-Samartín, A; Rodríguez-Puertas, R; Ruiz, A | 1 |
| Kim, M; Lee, CH; Lee, KW | 1 |
| Chen, H; Li, W; Li, Z; Liang, X; Martyniuk, CJ; Zha, J | 1 |
| He, GL; Li, P; Luo, X; Luo, Z; Shen, TT; Yang, J; Yang, XS | 1 |
| Asgharzadeh, F; Avan, A; Binabaj, MM; Ferns, GA; Hassanian, SM; Khazaei, M; Parizadeh, MR; Rahmani, F; Ryzhikov, M; Soleimani, A | 1 |
| Berdyyeva, T; Bhattacharya, A; Chen, G; He, Y; Huang, C; Kolb, H; Letavic, M; Szardenings, AK; Taylor, N; Xia, C; Zhang, W | 1 |
| Bakker, M; C Alffenaar, JW; Märtson, AG; Span, LFR; Touw, DJ; van den Heuvel, ER; van der Werf, TS; Veringa, A | 1 |
| Aires, ID; Ambrósio, AF; Boia, R; Madeira, MH; Marques, C; Rodrigues-Neves, AC; Santiago, AR | 1 |
| Asaka, N; Demizu, S; Kawahara, H; Sasaki, E | 1 |
| Abu-Serie, MM; AlFadly, ED; Bakkar, NZ; Bartolini, M; Belal, ASF; El-Yazbi, AF; Elkazaz, S; Elzahhar, PA; Ghareeb, DA; Iriepa, I; Janockova, J; Kobeissy, F; Moraleda, I; Rafeh, RW; Saudi, MNS; Shaltout, H; Soukup, O; Tramarin, A | 1 |
| Chen, J; Chen, X; Chen, Y; Gao, W; Hu, S; Jin, H; Lin, D; Tian, N; Wang, B; Wang, J; Wang, X; Wu, Y; Zhang, X; Zhou, Y | 1 |
| Jain, A; Piplani, P | 1 |
| Bereta, G; Bysiek, A; Chomyszyn-Gajewska, M; Gawron, K; Grabiec, AM; Kantorowicz, M; Lagosz, KB; Macina, JM; Maksylewicz, A; Potempa, J; Sochalska, M | 1 |
| Amo-Aparicio, J; Navarro, X; Penas, C; Sánchez-Ventura, J | 1 |
| Ashour, HM; Fahmy, SM; Ibrahim, TM; Khalil, MA; Labouta, IM; Nassra, RA; Tageldin, GN | 1 |
| Afshari, AR; Arjmand, MH; Asgharzadeh, F; Avan, A; Binabaj, MM; Fakhraei, M; Ferns, GA; Hassanian, SM; Khazaei, M; Mehraban, S; Naghinezhad, J; Parizadeh, MR; Rahmani, F; Ryzhikov, M; Sayyed-Hosseinian, SH; Soleimani, A | 1 |
| Ailawadi, G; Barbery, C; Bhamidipati, CM; Kron, IL; Laubach, VE; Meher, AK; Mehta, GS; Moehle, CW; Owens, GK; Sharma, AK; Su, G; Upchurch, GR; Vigneshwar, NG | 1 |
| Belkina, AC; Denis, GV; Nikolajczyk, BS | 1 |
| Acquaviva, J; Friedland, JC; He, S; Proia, DA; Sang, J; Smith, DL; Zhang, C | 1 |
| Bruce, SS; Connolly, ES; Heyer, EJ; Mergeche, JL | 1 |
| Carrillo-Salinas, FJ; Feliú, A; Guaza, C; Iñigo, PM; Mecha, M; Mestre, L | 1 |
| Brys, R; Christophe, T; Clement-Lacroix, P; Conrath, K; De Vos, S; Feyen, JH; Fletcher, S; Galien, R; Lepescheux, L; Menet, C; Nelles, L; Smets, B; van 't Klooster, G; van der Aar, EM; Van Rompaey, L; Vandeghinste, N; Vayssiere, B | 1 |
| Chen, YC; Chen, YJ; Hsu, MI; Huang, JH; Kao, YH; Lee, TI | 1 |
| Chang, CL; Chang, HW; Chang, LT; Chen, HH; Chen, YL; Chen, YT; Leu, S; Sun, CK; Sung, PH; Tsai, TH; Yang, CC; Yip, HK; Zhen, YY | 1 |
| Bradner, J; Decker, T; Jamieson, AM; Muhar, M; Müller, M; Rauch, I; Rosebrock, F; Wienerroither, S; Zuber, J | 1 |
| Moss, RB | 1 |
| Bardou-Jacquet, E; Beaumont-Epinette, MP; Ben Ali, Z; Brissot, P; Jouanolle, AM; Loreal, O | 1 |
| Bessi, VL; Bitencourt, CS; Borgeat, P; Faccioli, LH; Hamdan, L; Huynh, DN; Lefebvre, JS; Lévesque, T; Marleau, S; Ménard, L; Sohouhenou, F | 1 |
| Baldelli, F; Baroncelli, S; Cecchini, E; Falcinelli, E; Floridia, M; Francisci, D; Gresele, P; Petito, E; Weimer, LE | 1 |
| Adcock, IM; Barnes, PJ; Khan, YM; Kirkham, P | 1 |
| Ambrósio, AF; Fernandes, R; Gonçalves, A; Leal, E; Marques, C; Reis, F; Ribeiro, CF | 1 |
| Akassoglou, K; Biswas, D; Davalos, D; Garnier-Amblard, E; Gyoneva, S; Loth, F; Swanger, SA; Traynelis, SF | 1 |
| Fernandes, R; Fontes-Ribeiro, C; Gonçalves, A; Marques, C; Mega, C; Reis, F; Rodrigues-Santos, P; Teixeira, F; Teixeira-Lemos, E | 1 |
| Alam, MS; Alam, P; Ali, Y; Bano, S; Dhulap, A; Haider, S; Hamid, H; Hussain, F; Kharbanda, C; Nazreen, S; Pasha, MA; Shafi, S; Umar, S | 1 |
| Choi, YK; Jang, BK; Jung, GS; Jung, YA; Kim, HS; Kim, JG; Kim, MK; Lee, IK; Park, KG; Seo, HY | 1 |
| Alfonso, P; Andrade-Campos, M; Andreu, V; Gervas-Arruga, J; Giraldo, P; Irun, P; Medrano-Engay, B; Pocovi, M | 1 |
| Bair, S; Bradner, JE; Brown, JD; Croce, K; Duan, Q; Federation, A; Griffin, G; Kung, A; Lichtman, A; Lin, CY; Luscinskas, FW; Newton, G; Paranal, RM; Plutzky, J; Wang, H; Yang, T | 1 |
| Benemei, S; Coppi, E; De Logu, F; Di Tommaso, MR; Fusi, C; Geppetti, P; Marone, IM; Materazzi, S; Minocci, D; Moneti, G; Nassini, R; Pieraccini, G; Susini, T; Trevisan, G; Tuccinardi, T | 1 |
| Bugeon, L; Cheung, J; Dallman, MJ; Lamb, JR; Marchesi, JR; McBrien, M; Progatzky, F; Sangha, NJ; Scott, J; Shia, A; Yoshida, N | 1 |
| Agdauletova, S; Daiber, A; Hausding, M; Klein, T; Kröller-Schön, S; Li, H; Mader, M; Mikhed, Y; Münzel, T; Oelze, M; Pfeffer, A; Schulz, E; Stamm, P; Steven, S; Sudowe, S; Welschof, P; Zinßius, E | 1 |
| Bagchi, MK; Chen, Y; Gong, P; Katzenellenbogen, BS; Katzenellenbogen, JA; Ko, C; Korach, KS; Nettles, KW; Nwachukwu, JC; Srinivasan, S; Taylor, RN; Zhao, Y | 1 |
| Anderson, GP; Asselin-Labat, ML; Bozinovski, S; Burns, CJ; Donald, A; Dousha, L; Lilja, A; McArthur, K; Nguyen, T; Vlahos, R; Weeden, CE; Wong, ZX | 1 |
| Fahal, AH; Nenoff, P; Reinel, D; Schöfer, H; van de Sande, WW | 1 |
| Cataño-Cañizalez, YG; Cortés-Garcia, JD; Cortez-Espinosa, N; Guzman-Flores, JM; Portales-Perez, DP; Rodríguez-Rivera, JG; Vargas-Morales, JM | 1 |
| Ertan, M; Kazkayasi, I; Okay, G; Ozadali-Sari, K; Sarigol, D; Somuncuoglu, EI; Tel, BC; Tozkoparan, B; Unsal-Tan, O; Uzgoren-Baran, A | 1 |
| Best, C; Laciny, E; Reeds, DN; Royal, M; Struthers, H; Yarasheski, KE | 1 |
| Ambrósio, AF; Boia, R; Cunha, RA; Elvas, F; Gonçalves, FQ; Madeira, MH; Santiago, AR | 1 |
| Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Al-Hosaini, KA; Al-Sharary, SD; Ansari, MA; Attia, SM; El-Sherbeeny, AM; Nadeem, A; Siddiqui, N; Zoheir, KM | 1 |
| Filippakopoulos, P; Jarho, EM; Kokkola, T; Lahtela-Kakkonen, M; Pesonen, M; Salminen, A; Suuronen, T | 1 |
| Bilos, A; Geraci, S; Gretz, N; Heemskerk, S; Kraenzlin, B; Masereeuw, R; Peters, E; Pickkers, P; Wilmer, MJ | 1 |
| Adam, JM; Bendels, S; Bissantz, C; Fingerle, J; Grether, U; Grüner, S; Guba, W; Kimbara, A; Nettekoven, M; Ottaviani, G; Püllmann, B; Rogers-Evans, M; Rothenhäusler, B; Röver, S; Schmitt, S; Schuler, F; Schulz-Gasch, T; Ullmer, C | 1 |
| Aulí, M; Calama, E; de Alba, J; Domènech, T; Fonquerna, S; García-González, V; Lehner, MD; López, M; López, R; Miralpeix, M; Nueda, A; Planagumà, A; Pont, M; Prats, N; Ramos, I; Segarra, V | 1 |
| Bañales, JM; Becerril, JL; Benítez, JG; Juárez, JJ; Navarro, MD; Zerón, HM | 1 |
| Cho, KS; Choi, CS; Hong, SH; Jeon, SJ; Kim, JW; Shin, CY; Sim, S; Yang, SM; You, JS | 1 |
| Chai, JC; Chai, YG; Das, A; Das, ND; Jung, KH; Lee, YS; Yang, CS | 1 |
| Abdullah, T; Baggio, LL; Bang, KW; Campbell, JE; Drucker, DJ; Mulvihill, EE; Ussher, JR; Varin, EM | 1 |
| Baculi, F; Bates, RJ; Bennett, B; Blease, K; Brown, H; Burnett, K; Celeridad, M; Chamberlain, P; Delgado, M; Ferguson, GD; Haelewyn, J; Hickman, M; Jackson, P; Jensen-Pergakes, K; LeBrun, L; Miyazawa, K; Nadolny, L; Nguyen, T; Packard, G; Pagarigan, B; Pierce, S; Plantevin-Krenitsky, V; Tang, Y; Tehrani, L; Torres, S; Xie, W; Xu, L | 1 |
| Cucolaş, C; Dăneasă, A; Filip, GA; Lenghel, LM; Olteanu, D; Orăsan, R | 1 |
| Krishna, A; Pandey, U; Pandey, V; Singh, A; Tripathi, YB | 1 |
| Honkakoski, P; Hytti, M; Kaarniranta, K; Kauppinen, A; Korhonen, E; Lahtela-Kakkonen, M; Määttä, E; Piippo, N; Suuronen, T; Tokarz, P | 1 |
| Faghihi, MA; Magistri, M; Makhmutova, M; Patel, P; Sartor, GC; Velmeshev, D; Volmar, CH; Wahlestedt, C | 1 |
| Basler, C; Benner, C; Bouvier, N; Bukreyev, A; Campisi, L; Chen, X; Edwards, M; Fenouil, R; García-Sastre, A; Heinz, S; Ho, JSY; Jin, J; Jordan, S; Lagda, AC; Marazzi, I; Martinez-Gil, L; Merad, M; Metreveli, G; Munoz-Fontela, C; Peralta, Z; Pietzsch, C; Rialdi, A; van Bakel, H; Weirauch, M; Zhao, N | 1 |
| Lian, Y; Wang, W; Zhao, F | 1 |
| Han, X; Li, R; Liu, Y; Ran, Y; Su, M; Tan, Q; Yu, S; Zhang, X | 1 |
| Baldelli, F; Cipriani, S; Distrutti, E; Fiorucci, S; Francisci, D; Mencarelli, A; Santucci, L | 1 |
| Adcock, IM; Gambaryan, N; Humbert, M; Meng, C; Mumby, S; Perros, F; Wort, SJ | 1 |
| Cruz, HG; Dingemanse, J; Groenen, PM; Krause, A; Lott, D; Stalder, AK; Strasser, DS | 1 |
| Chen, G; Huang, M; Liang, L; Qiu, Q; Shi, M; Xiao, Y; Xu, H; Yang, X; Zeng, S; Zou, Y | 1 |
| Block, GA; Fishbane, S; Locatelli, F; Macdougall, IC | 1 |
| Akgul, B; Camci, C; Kalender, ME; Karakok, M; Sevinc, A; Turk, HM | 1 |
| Cervera, C; Crespo, G; Marco, F; Michelena, J; Moreno, A; Navasa, M | 1 |
| Jin, M; Koizumi, S; Linden, J; Odashima, M; Ohnishi, H; Otaka, M; Watanabe, S | 1 |
| Kalluraya, B; Rao, JN; Shetty, P; Sujith, KV | 1 |
| Fu, N; Li, LX; Liang, BL; Nan, YM; Wang, RQ; Wu, WJ; Yu, J; Zhao, JM; Zhao, SX | 1 |
| Ciccarelli, L; Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Franzetti, IG; Gadaleta, G; Maffioli, P; Piccinni, MN; Querci, F; Ragonesi, PD; Salvadeo, SA | 1 |
| Kubota, K; Kuwayama, T; Nakagawa, T; Sato, T; Sugihara, K; Suzuki, S | 1 |
| Li, GQ; Lu, HH; Mo, Q; Qian, J; Tang, LM; Wang, F; Wang, XH; Zhu, J; Zhu, JF | 1 |
| Fredholm, BB; Hao, JX; Li, L; Schulte, G; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
| Jiang, B; Li, MJ; Lu, T; Sun, NY; Wang, QJ; Wu, XM; Xu, JY; Zeng, Y; Zhang, YN | 1 |
| Coben, J; Dobrian, AD; Galkina, EV; Leone, KA; Lindsay, JW; Ma, K; Ma, Q; Nadler, JL | 1 |
| Asaka, N; Kakuo, H; Kiniwa, M; Ohmori, K; Oka, T; Sasaki, E; Togawa, M; Yamada, S | 1 |
| Bramanti, P; Cipriani, S; Corti, F; Cuzzocrea, S; Esposito, E; Mazzon, E; Melani, A; Mello, T; Paterniti, I; Pedata, F | 1 |
| Cronstein, BN; Williams, AJ | 1 |
| De Luca, A; Dello Russo, C; Lisi, L; Navarra, P; Tramutola, A | 1 |
| Faldyna, M; Kovaru, F; Kovaru, H; Leva, L; Matiasovic, J; Ondrackova, P | 1 |
| Guo, L; Hao, X; Ju, R; Li, J; Luo, L; Wang, C; Wu, D; Ye, C; Yu, X; Zhang, D; Zheng, R; Zhu, L | 1 |
| Barbieri, M; Marfella, R; Paolisso, G; Rizzo, MR | 1 |
| Bell, K; Bergamini, G; Ellard, K; Neubauer, G; Ramsden, N; Sunose, M; Werner, T | 1 |
| El-Agamy, DS; El-Awady, MS; Nader, MA; Shalaby, AA | 1 |
| Isogawa, A; Iwamoto, M; Koike, K; Ohki, T; Ohsugi, M; Omata, M; Tagawa, K; Toda, N; Yoshida, H | 1 |
| Burton, VJ; Butler, M; Parkinson, SJ; Pearson, R; Sanmugalingam, D; Smith, P; Watson, RP; Wilson, T | 1 |
| Hasegawa, K; Iguchi, A; Kono, S; Nakagawachi, R; Odori, S; Sasaki, Y; Satoh-Asahara, N; Shimatsu, A; Tochiya, M; Wada, H | 1 |
| Adibekian, A; Cravatt, BF; Hsu, KL; Masuda, K; Pugh, H; Tsuboi, K | 1 |
| Assis, SP; da Silva, MT; de Oliveira, RN; Lima, VL | 1 |
| Díaz-Delfín, J; Domingo, P; Giralt, M; Villarroya, F | 1 |
| Barbieri, M; Boccardi, V; Esposito, A; Marfella, R; Pansini, A; Paolisso, G; Rizzo, MR | 1 |
| Muller, CD; Peluso, J; Saab, L; Ubeaud-Sequier, G | 1 |
| Magnusson, JE; Teather, LA; Wurtman, RJ | 1 |
| Chi, EY; Henderson, WR; Kahn, M; Nguyen, C; Teo, JL | 1 |
| Chapler, CK; King-VanVlack, CE; MacDonald, PH; Mewburn, JD | 1 |
| Barreiro, EJ; Castro, HC; Cunha, AC; de Souza, MC; Ferreira, VF; Figueiredo, JM; Fraga, CA; Miranda, AL; Tributino, JL; Zingali, RB | 1 |
| BUCHSCHACHER, P; FRIED, JH; HANNAH, J; MROZIK, H | 1 |
| Abe, S; Hiraga, Y; Sato, N; Shigehara, K; Shijubo, N; Takahashi, R | 1 |
| Calixto, JB; Kassuya, CA; Marotta, DM; Menezes-de-Lima, O; Rehder, VL; Silvestre, A | 1 |
| Di Braccio, M; Gosmar, M; Grossi, G; Mattioli, F; Piras, D; Roma, G | 1 |
| Huhtaniemi, I; Mäkelä, S; Pakarainen, T; Poutanen, M; Savolainen, S | 1 |
| Amir, M; Javed, SA; Kumar, H | 1 |
| Baumane, L; Dambrova, M; Kalvinsh, I; Liepinsh, E; Muceniece, R; Vilskersts, R; Wikberg, JE; Zvejniece, L | 1 |
| Ahmadi, S; Brockhaus, J; Brune, K; Fritschy, JM; Hess, A; Hösl, K; Knabl, J; Möhler, H; Reinold, H; Rudolph, U; Sergejeva, M; Witschi, R; Zeilhofer, HU; Zeilhofer, UB | 1 |
| Hay, DW; Hubbard, WC; Undem, BJ | 1 |
| Das, A; Larkin, SW; Nourshargh, S; Williams, TJ | 1 |
| Bergmann, R; Gokel, M; Hammer, C; Saumweber, DM | 1 |
| Hariprasad, V; Nargund, LV; Redd, GR | 1 |
| Bozza, PT; Castro Faria Neto, HC; Cordeiro, RS; e Silva, PM; Lima, MC; Martins, MA; Vargaftig, BB | 1 |
| Gaboury, JP; Kubes, P; Niu, XF | 1 |
| Baker, R; Cascieri, MA; Chambers, MS; Hargreaves, RJ; Haworth, K; Keown, LE; Ladduwahetty, T; MacIntyre, DE; Metzger, JM; Owen, S; Rycroft, W; Sadowski, S; Seward, EM; Shepheard, SL; Swain, CJ; Tattersall, FD; Watt, AP; Williamson, DW | 1 |
| Gingras, D; Lacasse, C; Rola-Pleszczynski, M; Stankova, J; Turcotte, S | 1 |
| Desouza, IA; Ribeiro-DaSilva, G | 1 |
| Branch, RA; Carcillo, JA; Gillespie, DG; Jones, GS; Kochanek, PM; Korzekwa, KR; Kost, CK; Parise, RA; Whalen, MJ | 1 |
| Chilvers, ER; Haslett, C; Murray, J; Rahman, I; Rossi, AG; Ward, C; Wong, TH | 1 |
| Anderson, R; Ramafi, G; Theron, AJ; Visser, SS | 1 |
| Barringhaus, KG; Bishop, GG; Gimple, LW; Hesselbacher, SE; Linden, J; Macdonald, T; McPherson, JA; Powers, ER; Rieger, JM; Sanders, JM; Sarembock, IJ; Sullivan, G | 1 |
| Ellis, KM; Fozard, JR; Mazzoni, L; Tigani, B; Villela Dantas, MF | 1 |
| Carlson, SL; Hostettler, ME; Knapp, PE | 1 |
| Ayala, E; Canonico, PG; Rill, W | 1 |
| Buckman, D; Iverson, L; Srivastava, A; Thomas, TK; Weis, W; Will, PC; Wilson, C | 1 |
| Conklyn, M; Conyers, G; Cramer, E; Milks, L; Showell, H | 1 |
| Barnett, A; Berger, JG; Chipkin, RE; Iorio, LC; Latranyi, MB | 1 |
| Zagórski, Z | 1 |
| Assandri, A; Bassi, L; Filippeschi, S; Galliani, G; Mistrello, G | 1 |
9 review(s) available for triazoles and Inflammation
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide | 2023 |
JAK-STAT inhibitors: Immersing therapeutic approach for management of rheumatoid arthritis.
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Azetidines; Clinical Trials as Topic; Cytokines; Humans; Inflammation; Janus Kinase Inhibitors; Janus Kinases; Protein Kinase Inhibitors; Purines; Pyrazoles; Pyridines; Signal Transduction; STAT Transcription Factors; Sulfonamides; Triazoles | 2020 |
Filgotinib: First Approval.
Topics: Antirheumatic Agents; Autoimmune Diseases; Humans; Inflammation; Japan; Protein Kinase Inhibitors; Pyridines; Triazoles | 2020 |
Exploring the Chemistry and Therapeutic Potential of Triazoles: A Comprehensive Literature Review.
Topics: Humans; Infections; Inflammation; Neoplasms; Neurodegenerative Diseases; Oxidative Stress; Seizures; Triazoles | 2019 |
Treatment options in severe fungal asthma and allergic bronchopulmonary aspergillosis.
Topics: Adrenal Cortex Hormones; Amphotericin B; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Aspergillus fumigatus; Asthma; Clinical Trials as Topic; Humans; Inflammation; Triazoles | 2014 |
Non-HFE hemochromatosis: pathophysiological and diagnostic aspects.
Topics: Alcohol Drinking; Benzoates; Biopsy; Cataract; Cation Transport Proteins; Decision Trees; Deferasirox; Diet; Gaucher Disease; Genetic Testing; Hemochromatosis; Hemochromatosis Protein; Hepcidins; Histocompatibility Antigens Class I; Humans; Inflammation; Iron; Iron Chelating Agents; Iron Metabolism Disorders; Iron Overload; Liver; Macrophage Activation Syndrome; Magnetic Resonance Imaging; Membrane Proteins; Metabolic Syndrome; Mutation; Phlebotomy; Receptors, Transferrin; Transferrin; Triazoles | 2014 |
Eumycetoma and actinomycetoma--an update on causative agents, epidemiology, pathogenesis, diagnostics and therapy.
Topics: Actinomycetales; Actinomycetales Infections; Amputation, Surgical; Animals; Anti-Bacterial Agents; Antifungal Agents; Cytokines; Debridement; Diagnosis, Differential; Humans; Inflammation; Itraconazole; Madurella; Mycetoma; Naphthalenes; Terbinafine; Triazoles | 2015 |
Combined anti CXC receptors 1 and 2 therapy is a promising anti-inflammatory treatment for respiratory diseases by reducing neutrophil migration and activation.
Topics: Animals; Benzamides; Cell Line; Cricetinae; Cyclobutanes; Guinea Pigs; Humans; Inflammation; Interleukin-8; Lipopolysaccharides; Lung; Male; Neutrophils; Phenylurea Compounds; Reactive Oxygen Species; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Signal Transduction; Triazoles | 2015 |
Targeting Hypoxia-Inducible Factors for the Treatment of Anemia in Chronic Kidney Disease Patients.
Topics: Anemia; Animals; Barbiturates; Blood Pressure; Disease Models, Animal; Drug Design; Drug Interactions; Glycine; Hepcidins; Humans; Hypoxia-Inducible Factor 1; Inflammation; Isoquinolines; Kidney Failure, Chronic; Picolinic Acids; Protein Domains; Pyrazoles; Triazoles | 2017 |
10 trial(s) available for triazoles and Inflammation
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide | 2023 |
Characterisation of the pharmacodynamic effects of the P2X7 receptor antagonist JNJ-54175446 using an oral dexamphetamine challenge model in healthy males in a randomised, double-blind, placebo-controlled, multiple ascending dose trial.
Topics: Adolescent; Adult; Central Nervous System Stimulants; Depressive Disorder, Major; Dextroamphetamine; Double-Blind Method; Electroencephalography; Humans; Inflammation; Male; Purinergic P2X Receptor Antagonists; Pyridines; Translational Research, Biomedical; Triazoles; Young Adult | 2020 |
Impact of intensified antiretroviral therapy during early HIV infection on gut immunology and inflammatory blood biomarkers.
Topics: Adult; Anti-HIV Agents; Biomarkers; Canada; Cyclohexanes; Double-Blind Method; Drug Therapy, Combination; Fibrin Fibrinogen Degradation Products; Flow Cytometry; HIV Infections; Humans; Immunity, Mucosal; Inflammation; Intestinal Mucosa; Lymphocyte Activation; Male; Maraviroc; Middle Aged; Prospective Studies; Raltegravir Potassium; Th17 Cells; Treatment Outcome; Triazoles; Young Adult | 2017 |
Sitagliptin Reduces Inflammation and Chronic Immune Cell Activation in HIV+ Adults With Impaired Glucose Tolerance.
Topics: Adipokines; Adult; Chemokines; Endothelial Progenitor Cells; Female; Glucose Intolerance; HIV Infections; HIV-1; Humans; Hypoglycemic Agents; Inflammation; Lymphocyte Activation; Male; Middle Aged; Pyrazines; Sitagliptin Phosphate; Triazoles | 2015 |
Biomarker-guided clinical development of the first-in-class anti-inflammatory FPR2/ALX agonist ACT-389949.
Topics: Adolescent; Adult; Animals; Biomarkers; Cell Migration Assays; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Inflammation; Lipopolysaccharides; Male; Middle Aged; Neutrophils; Oxazoles; Receptors, Formyl Peptide; Receptors, Lipoxin; Triazoles; Young Adult | 2017 |
Effects of sitagliptin or metformin added to pioglitazone monotherapy in poorly controlled type 2 diabetes mellitus patients.
Topics: Adiponectin; Blood Glucose; Body Weight; C-Reactive Protein; Diabetes Mellitus, Type 2; Diet; Double-Blind Method; Drug Therapy, Combination; Exercise; Female; Humans; Hypoglycemic Agents; Inflammation; Insulin Resistance; Insulin-Secreting Cells; Male; Metformin; Middle Aged; Pioglitazone; Pyrazines; Resistin; Sitagliptin Phosphate; Thiazolidinediones; Triazoles; Tumor Necrosis Factor-alpha | 2010 |
Reduction of oxidative stress and inflammation by blunting daily acute glucose fluctuations in patients with type 2 diabetes: role of dipeptidyl peptidase-IV inhibition.
Topics: Adamantane; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Female; Glycated Hemoglobin; Humans; Inflammation; Interleukin-18; Interleukin-6; Male; Metformin; Middle Aged; Nitriles; Oxidative Stress; Postprandial Period; Prospective Studies; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Triazoles; Vildagliptin | 2012 |
Impairment of adenosine A3 receptor activity disrupts neutrophil migratory capacity and impacts innate immune function in vivo.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Animals; Chemotaxis; Colitis; Dextran Sulfate; Disease Models, Animal; Humans; Immunity, Innate; Inflammation; Mice; Mice, Knockout; Neutrophils; Quinazolines; Receptor, Adenosine A3; Triazoles; Up-Regulation | 2012 |
A dipeptidyl peptidase-4 inhibitor, sitagliptin, exerts anti-inflammatory effects in type 2 diabetic patients.
Topics: Blood Glucose; C-Reactive Protein; Cholesterol; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Female; Glucagon-Like Peptide 1; Humans; Inflammation; Interleukin-10; Interleukin-6; Leukocytes, Mononuclear; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Pyrazines; Regression Analysis; Serum Amyloid A Protein; Sitagliptin Phosphate; Triazoles; Tumor Necrosis Factor-alpha | 2013 |
Decreased carotid atherosclerotic process by control of daily acute glucose fluctuations in diabetic patients treated by DPP-IV inhibitors.
Topics: Adamantane; Atherosclerosis; Blood Glucose; Carotid Arteries; Carotid Artery Diseases; Carotid Intima-Media Thickness; Cytokines; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Glycated Hemoglobin; Humans; Inflammation; Nitriles; Oxidative Stress; Prospective Studies; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Triazoles; Tyrosine; Vildagliptin | 2013 |
161 other study(ies) available for triazoles and Inflammation
| Article | Year |
|---|---|
Filgotinib decreases both vertebral body and posterolateral spine inflammation in ankylosing spondylitis: results from the TORTUGA trial.
Topics: Humans; Inflammation; Magnetic Resonance Imaging; Pyridines; Severity of Illness Index; Spine; Spondylarthritis; Spondylitis, Ankylosing; Triazoles; Vertebral Body; Zygapophyseal Joint | 2022 |
Indole-linked 1,2,3-triazole derivatives efficiently modulate COX-2 protein and PGE
Topics: Cyclooxygenase 2; Cytokines; Dinoprostone; Glycation End Products, Advanced; Humans; Indoles; Inflammation; Inflammation Mediators; Monocytes; NF-kappa B; Reactive Oxygen Species; THP-1 Cells; Triazoles | 2022 |
BRD4 Inhibition Attenuates Inflammatory Pain by Ameliorating NLRP3 Inflammasome-Induced Pyroptosis.
Topics: Animals; Azepines; Cell Line; Disease Models, Animal; Freund's Adjuvant; Hyperalgesia; Inflammasomes; Inflammation; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Nuclear Proteins; Pain; Pyroptosis; Signal Transduction; Transcription Factors; Triazoles | 2022 |
EW-7197 Attenuates the Progression of Diabetic Nephropathy in db/db Mice through Suppression of Fibrogenesis and Inflammation.
Topics: Aniline Compounds; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Inflammation; Mice; Triazoles | 2022 |
Difenoconazole causes cardiotoxicity in common carp (Cyprinus carpio): Involvement of oxidative stress, inflammation, apoptosis and autophagy.
Topics: Animals; Apoptosis; Autophagy; Cardiotoxicity; Carps; Cytokines; Dioxolanes; Inflammation; Oxidative Stress; Phosphatidylinositol 3-Kinases; Triazoles | 2022 |
Triazole-derivatized near-infrared cyanine dyes enable local functional fluorescent imaging of ocular inflammation.
Topics: Animals; Biosensing Techniques; Fluorescent Dyes; Humans; Indocyanine Green; Inflammation; Optical Imaging; Swine; Triazoles | 2022 |
FASN inhibition targets multiple drivers of NASH by reducing steatosis, inflammation and fibrosis in preclinical models.
Topics: Actins; Animals; Carcinoma, Hepatocellular; Cytokines; Disease Models, Animal; Fatty Acid Synthase, Type I; Fatty Acid Synthases; Humans; Inflammation; Lipopolysaccharides; Liver Cirrhosis; Liver Neoplasms; Mice; Nitriles; Non-alcoholic Fatty Liver Disease; Piperidines; Triazoles; Triglycerides | 2022 |
Widening the Lens on Prothioconazole and Its Metabolite Prothioconazole-Desthio: Aryl Hydrocarbon Receptor-Mediated Reproductive Disorders through
Topics: Animals; Environmental Exposure; Fungicides, Industrial; Inflammation; Mice; Ovary; Receptors, Aryl Hydrocarbon; Triazoles | 2022 |
Triazoles with inhibitory action on P2X7R impaired the acute inflammatory response in vivo and modulated the hemostatic balance in vitro and ex vivo.
Topics: Animals; Carrageenan; Edema; Hemostatics; Inflammation; Mice; Molecular Docking Simulation; Peritonitis; Triazoles | 2023 |
Crosstalk of oxidative stress, inflammation, apoptosis, and autophagy under reactive oxygen stress involved in difenoconazole-induced kidney damage in carp.
Topics: Animals; Apoptosis; Autophagy; Carps; Inflammation; Kidney; Oxidative Stress; Oxygen; Reactive Oxygen Species; Signal Transduction; Triazoles | 2023 |
BRD4 suppression alleviates cerebral ischemia-induced brain injury by blocking glial activation via the inhibition of inflammatory response and pyroptosis.
Topics: Animals; Azepines; Brain Injuries; Brain Ischemia; Cell Survival; Cells, Cultured; Inflammation; Male; Mice; Mice, Inbred C57BL; Neuroglia; Nuclear Proteins; Pyroptosis; Transcription Factors; Triazoles | 2019 |
1,2,4-Triazole-conjugated 1,3,4-thiadiazole hybrid scaffolds: A potent ameliorant of carrageenan-induced inflammation by lessening proinflammatory mediators.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Edema; Inflammation; Inflammation Mediators; Molecular Docking Simulation; Molecular Structure; Quantitative Structure-Activity Relationship; Rats; Rats, Wistar; Thiadiazoles; Triazoles | 2020 |
[1,2,4]Triazolo[1,5-a]pyrimidine derivative (Mol-5) is a new NS5-RdRp inhibitor of DENV2 proliferation and DENV2-induced inflammation.
Topics: Animals; Antiviral Agents; Cell Proliferation; Cells, Cultured; Cricetinae; Dengue; Dengue Virus; Inflammation; Microbial Sensitivity Tests; Molecular Docking Simulation; Pyrimidines; Recombinant Proteins; RNA-Dependent RNA Polymerase; Surface Plasmon Resonance; Triazoles; Viral Nonstructural Proteins | 2020 |
Different effects of exposure to penconazole and its enantiomers on hepatic glycolipid metabolism of male mice.
Topics: Animals; Fungicides, Industrial; Glycolipids; Inflammation; Lipid Metabolism; Liver; Magnetic Resonance Spectroscopy; Male; Metabolomics; Mice; Oxidation-Reduction; Stereoisomerism; Toxicity Tests; Triazoles | 2020 |
Targeting bromodomain-containing proteins to prevent spontaneous preterm birth.
Topics: Animals; Azepines; Cell Cycle Proteins; Female; Humans; Inflammation; Lipopolysaccharides; Mice; Myometrium; Obstetric Labor, Premature; Pregnancy; Premature Birth; RNA, Small Interfering; Transcription Factors; Triazoles | 2019 |
Bromodomain-containing protein 4 inhibition alleviates matrix degradation by enhancing autophagy and suppressing NLRP3 inflammasome activity in NP cells.
Topics: Animals; Autophagy; Azepines; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Inflammasomes; Inflammation; Intervertebral Disc Degeneration; Macrolides; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Nuclear Proteins; Nucleus Pulposus; Rats; Signal Transduction; Transcription Factor RelA; Transcription Factors; Triazoles | 2020 |
Can anti-inflammatory strategies light up the dim depression pipeline?
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Depression; Depressive Disorder; Drug Discovery; Humans; Inflammation; Pyridines; Triazoles | 2020 |
1,4-Disubstituted 1
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cell Survival; Cellobiose; Crystallography, X-Ray; Cyclooxygenase 2; Free Radicals; Group IV Phospholipases A2; Humans; Inflammation; Kidney Diseases; Lipopolysaccharides; Matrix Metalloproteinase 9; Mesangial Cells; Mitochondria; Molecular Docking Simulation; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Triazoles | 2020 |
Molecular dynamic simulations of full-length human purinergic receptor subtype P2X7 bonded to potent inhibitors.
Topics: Adenosine Triphosphate; Anions; Humans; Inflammation; Ligands; Molecular Dynamics Simulation; Receptors, Purinergic P2X7; Triazoles | 2020 |
Adenosine Receptors as Neuroinflammation Modulators: Role of A
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Cells, Cultured; Inflammation; Male; Neuroglia; Neurons; Rats, Wistar; Receptors, Purinergic P1; Triazines; Triazoles | 2020 |
The BRD4 inhibitor JQ1 protects against chronic obstructive pulmonary disease in mice by suppressing NF-κB activation.
Topics: Animals; Azepines; Cytokines; Gene Expression Regulation; Inflammation; Leukocytes; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred BALB C; NF-kappa B p50 Subunit; Nuclear Proteins; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Respiratory Function Tests; Signal Transduction; Transcription Factors; Triazoles | 2021 |
BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy.
Topics: Animals; Azepines; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; NADP; NADPH Oxidases; Neuromuscular Diseases; Nuclear Proteins; Oxidative Stress; Reactive Oxygen Species; Transcription Factors; Triazoles | 2020 |
Design and synthesis of 7-O-1,2,3-triazole hesperetin derivatives to relieve inflammation of acute liver injury in mice.
Topics: Animals; Carbon Tetrachloride; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Design; Hesperidin; Inflammation; Liver; Mice; Mice, Inbred C57BL; Molecular Structure; Nitric Oxide; RAW 264.7 Cells; Reactive Oxygen Species; Structure-Activity Relationship; Triazoles | 2021 |
New Substituted 5-Benzylideno-2-Adamantylthiazol[3,2-b][1,2,4]Triazol-6(5
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Female; Humans; Inflammation; Lipoxygenase; Lipoxygenase Inhibitors; Male; Mice; Molecular Docking Simulation; Naproxen; Structure-Activity Relationship; Triazoles | 2021 |
Inhibition of Urea Transporter (UT)-B Modulates LPS-Induced Inflammatory Responses in BV2 Microglia and N2a Neuroblastoma Cells.
Topics: Animals; Cell Line, Tumor; Inflammation; Interleukin-6; Lipopolysaccharides; Membrane Transport Proteins; Mice; Microglia; Neuroblastoma; Nitric Oxide; Pyrimidines; Thiophenes; Triazoles; Tumor Necrosis Factor-alpha; Urea Transporters | 2021 |
Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function.
Topics: Arthritis, Rheumatoid; Azepines; Cell Cycle Proteins; Cytokines; Healthy Volunteers; Heterocyclic Compounds, 2-Ring; High-Throughput Nucleotide Sequencing; Humans; Inflammation; Killer Cells, Natural; Piperazines; Pyrazoles; Pyridazines; Transcription Factors; Transcriptome; Triazoles | 2021 |
The BET inhibitor attenuates the inflammatory response and cell migration in human microglial HMC3 cell line.
Topics: Azepines; Cell Line; Cell Movement; Gene Expression Regulation; Humans; Inflammation; Lipopolysaccharides; Microglia; Proteins; RNA, Messenger; Transcription Factors; Triazoles | 2021 |
Design and synthesis of novel diosgenin-triazole hybrids targeting inflammation as potential neuroprotective agents.
Topics: Alzheimer Disease; Animals; Cell Line; Diosgenin; Dose-Response Relationship, Drug; Drug Design; Inflammation; Lipopolysaccharides; Molecular Conformation; Neuroprotective Agents; Nitric Oxide; Rats; Structure-Activity Relationship; Triazoles | 2021 |
Optimization of pyrazole-based compounds with 1,2,4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory, ulcerogenicity, cardiovascular evaluation, and mol
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiotonic Agents; Carrageenan; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Design; Edema; Inflammation; Male; Models, Molecular; Molecular Structure; Pyrazoles; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship; Triazoles | 2021 |
Targeting JAK-STAT Signalling Alters PsA Synovial Fibroblast Pro-Inflammatory and Metabolic Function.
Topics: Adamantane; Adult; Aged; Arthritis, Psoriatic; Azetidines; Cells, Cultured; Female; Fibroblasts; Heterocyclic Compounds, 3-Ring; Humans; Inflammation; Janus Kinase Inhibitors; Janus Kinases; Male; Middle Aged; Niacinamide; Purines; Pyrazoles; Pyridines; Signal Transduction; STAT Transcription Factors; Sulfonamides; Synovial Membrane; Triazoles | 2021 |
P2Y14R for inflammation therapy: is it a promising target?
Topics: Anti-Inflammatory Agents; Benzofurans; Benzoic Acid; Biomarkers; Drug Evaluation, Preclinical; Humans; Inflammation; Naphthalenes; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Structure-Activity Relationship; Triazoles | 2021 |
Cytohesin-2 mediates group I metabotropic glutamate receptor-dependent mechanical allodynia through the activation of ADP ribosylation factor 6 in the spinal cord.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factor 6; Animals; GTPase-Activating Proteins; Hyperalgesia; Inflammation; MAP Kinase Signaling System; Methoxyhydroxyphenylglycol; Mice; Mice, Knockout; Neuralgia; Post-Synaptic Density; Posterior Horn Cells; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Spinal Cord; Spinal Cord Dorsal Horn; Triazoles | 2021 |
Epigenetic intervention with a BET inhibitor ameliorates acute retinal ganglion cell death in mice.
Topics: Animals; Apoptosis; Azepines; Cell Count; Cytokines; Epigenesis, Genetic; Female; Gene Expression Regulation; Inflammation; Male; Mice, Inbred C57BL; N-Methylaspartate; Nuclear Proteins; Retinal Ganglion Cells; Triazoles | 2017 |
Lignin-graft-Polyoxazoline Conjugated Triazole a Novel Anti-Infective Ointment to Control Persistent Inflammation.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Cell Survival; Inflammation; Interleukin-1beta; Lignin; Macrophages; NF-kappa B; Ointments; Rats; Rats, Sprague-Dawley; Triazoles; Wound Healing | 2017 |
BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure.
Topics: Animals; Azepines; Cardiomegaly; Gene Regulatory Networks; Heart Failure; Humans; Induced Pluripotent Stem Cells; Inflammation; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; NF-kappa B; Proteins; Signal Transduction; Transforming Growth Factor beta; Triazoles | 2017 |
Co-incubation of PMN and CaCo-2 cells modulates inflammatory potential.
Topics: Aspirin; Azepines; Caco-2 Cells; Calcimycin; Humans; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; omega-N-Methylarginine; Pancreatic Elastase; Respiratory Burst; Triazoles | 2017 |
1-Aryl-1H- and 2-aryl-2H-1,2,3-triazole derivatives blockade P2X7 receptor in vitro and inflammatory response in vivo.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Inflammation; Lipopolysaccharides; Mice; Molecular Structure; Pleurisy; Receptors, Purinergic P2X7; Structure-Activity Relationship; Triazoles | 2017 |
Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo.
Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Disease Models, Animal; Enzyme Inhibitors; Humans; Hyperalgesia; Inflammation; Lipopolysaccharides; Lipoprotein Lipase; Liposomes; Macrophages; Male; Mice; Mice, Inbred C57BL; Pain; Phagocytosis; Treatment Outcome; Triazoles; Urea | 2018 |
MG17, A Novel Triazole Derivative Abrogated Neuroinflammation and Related Neurodegenerative Symptoms in Rodents.
Topics: Animals; Brain; Carrageenan; Cell Survival; Diabetic Neuropathies; Edema; Inflammation; Inhibitory Concentration 50; Male; Mice; Motor Activity; Nerve Degeneration; Rats, Wistar; rho-Associated Kinases; RNA, Messenger; Triazoles | 2018 |
Oxidative stress burden inhibits spermatogenesis in adult male rats: testosterone protective effect.
Topics: Aging; Animals; Biomarkers; Body Weight; Estradiol; Follicle Stimulating Hormone; Grape Seed Extract; Inflammation; Letrozole; Male; Methotrexate; Nitriles; Organ Size; Oxidative Stress; Protective Agents; Rats, Sprague-Dawley; Seminiferous Tubules; Sperm Count; Sperm Motility; Spermatogenesis; Testosterone; Triazoles | 2018 |
Contrasting effect of the latency-reversing agents bryostatin-1 and JQ1 on astrocyte-mediated neuroinflammation and brain neutrophil invasion.
Topics: Adjuvants, Immunologic; Astrocytes; Azepines; Brain; Bryostatins; Chemotaxis, Leukocyte; HIV-1; Humans; Inflammation; Neutrophils; Triazoles; Virus Activation; Virus Latency | 2017 |
Spinal Sigma-1 Receptor-mediated Dephosphorylation of Astrocytic Aromatase Plays a Key Role in Formalin-induced Inflammatory Nociception.
Topics: Animals; Aromatase; Aromatase Inhibitors; Astrocytes; Calcineurin; Formaldehyde; Glial Fibrillary Acidic Protein; Inflammation; Letrozole; Male; Mice, Inbred ICR; Nitriles; Nociceptive Pain; Oncogene Proteins v-fos; Phosphorylation; Receptors, sigma; Sigma-1 Receptor; Spinal Cord; Triazoles | 2018 |
3-Substituted 1,5-Diaryl-1 H-1,2,4-triazoles as Prospective PET Radioligands for Imaging Brain COX-1 in Monkey. Part 1: Synthesis and Pharmacology.
Topics: Animals; Brain; Carbon Radioisotopes; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Fluorine Radioisotopes; Inflammation; Macaca mulatta; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Triazoles | 2018 |
Bromodomain and extraterminal domain-containing protein inhibition attenuates acute inflammation after spinal cord injury.
Topics: Animals; Animals, Newborn; Azepines; Cells, Cultured; Chromosomal Proteins, Non-Histone; Cytokines; Disease Models, Animal; Exploratory Behavior; Flow Cytometry; Gene Expression Regulation; Inflammation; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroglia; Nuclear Proteins; Receptors, Cell Surface; RNA, Messenger; Spinal Cord Injuries; Transcription Factors; Triazoles | 2018 |
Re-examining the potential of targeting ABHD6 in multiple sclerosis: Efficacy of systemic and peripherally restricted inhibitors in experimental autoimmune encephalomyelitis.
Topics: Animals; Benzoates; Biphenyl Compounds; Brain; Calcium; Carbamates; Cells, Cultured; Encephalomyelitis, Autoimmune, Experimental; Female; Inflammation; Mice; Mitochondria; Molecular Targeted Therapy; Monoacylglycerol Lipases; N-Methylaspartate; Neural Conduction; Piperidines; Pyramidal Tracts; Receptor, Cannabinoid, CB1; Triazoles | 2018 |
Treatment of Dextran Sulfate Sodium-Induced Colitis with Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Inhibitor MI-2 Is Associated with Restoration of Gut Immune Function and the Microbiota.
Topics: Acetanilides; Animals; Cells, Cultured; Colitis; Cytokines; Dextran Sulfate; Fecal Microbiota Transplantation; Feces; Female; Gastrointestinal Microbiome; Humans; Inflammation; Intestines; Macrophages; Mice; Mice, Inbred C57BL; Monocytes; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Triazoles | 2018 |
Transcriptome analysis reveals benzotriazole ultraviolet stabilizers regulate networks related to inflammation in juvenile zebrafish (Danio rerio) brain.
Topics: Animals; Brain; Gene Expression Profiling; Inflammation; Transcriptome; Triazoles; Ultraviolet Rays; Water Pollutants, Chemical; Zebrafish | 2019 |
Inhibition of HSP90β by ganetespib blocks the microglial signalling of evoked pro-inflammatory responses to heat shock.
Topics: Animals; Cell Line, Transformed; Heat-Shock Response; HSP90 Heat-Shock Proteins; Inflammation; MAP Kinase Signaling System; Mice; Microglia; STAT3 Transcription Factor; Triazoles | 2019 |
EW-7197 prevents ulcerative colitis-associated fibrosis and inflammation.
Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis, Ulcerative; Colon; Fibrosis; Inflammation; Male; Mice, Inbred C57BL; Oxidative Stress; Triazoles | 2019 |
PET Imaging of the P2X7 Ion Channel with a Novel Tracer [
Topics: Animals; Biomarkers; Brain; Disease Models, Animal; Inflammation; Lipopolysaccharides; Peptides; Pilot Projects; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Pyridines; Radiopharmaceuticals; Rats; Receptors, Purinergic P2X7; Triazoles | 2019 |
Posaconazole trough concentrations are not influenced by inflammation: A prospective study.
Topics: Adult; Aged; Antifungal Agents; C-Reactive Protein; Female; Humans; Inflammation; Longitudinal Studies; Male; Middle Aged; Mycoses; Plasma; Prospective Studies; Triazoles; Young Adult | 2019 |
Blockade of microglial adenosine A
Topics: Adenosine A2 Receptor Antagonists; Adult; Aged; Animals; Animals, Newborn; Cell Death; Cell Proliferation; Cells, Cultured; Cytokines; Female; Gene Expression Regulation; Humans; Inflammation; Male; Microglia; Middle Aged; Neurons; Organ Culture Techniques; Oxidative Stress; Phagocytosis; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Retina; Triazoles; Wounds and Injuries | 2019 |
TAS-203, an oral phosphodiesterase 4 inhibitor, exerts anti-inflammatory activities in a rat airway inflammation model.
Topics: Animals; Benzimidazoles; Cigarette Smoking; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Gene Expression Regulation; Goblet Cells; Guinea Pigs; Hyperplasia; Inflammation; Male; Mucin 5AC; Phosphodiesterase 4 Inhibitors; Pulmonary Disease, Chronic Obstructive; Rats; Respiratory System; Triazoles | 2019 |
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase.
Topics: Acetylcholine; Alzheimer Disease; Animals; Cell Line; Cholinesterase Inhibitors; Cyclooxygenase 2 Inhibitors; Drug Design; Humans; Inflammation; Lipoxygenase Inhibitors; Mice; Molecular Docking Simulation; Neurons; PC12 Cells; Rats; Semicarbazides; Triazoles | 2019 |
BRD4 inhibition attenuates inflammatory response in microglia and facilitates recovery after spinal cord injury in rats.
Topics: Animals; Azepines; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation; MAP Kinase Kinase 1; Microglia; NF-kappa B; Nuclear Proteins; Rats; Recovery of Function; Signal Transduction; Spinal Cord; Spinal Cord Injuries; Transcription Factors; Triazoles | 2019 |
BET Bromodomain Inhibitors Suppress Inflammatory Activation of Gingival Fibroblasts and Epithelial Cells From Periodontitis Patients.
Topics: Animals; Azepines; Cytokines; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gingiva; Heterocyclic Compounds, 4 or More Rings; Humans; Inflammation; Mice; Periodontitis; Porphyromonas gingivalis; Triazoles | 2019 |
BET protein inhibition regulates cytokine production and promotes neuroprotection after spinal cord injury.
Topics: Animals; Azepines; Cytokines; Female; Inflammation; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroprotective Agents; Receptors, Cell Surface; Recovery of Function; Spinal Cord Injuries; Triazoles | 2019 |
Synthesis, modeling and biological evaluation of some pyrazolo[3,4-d]pyrimidinones and pyrazolo[4,3-e][1,2,4]triazolo[4,3-a]pyrimidinones as anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Edema; Female; Granuloma; Inflammation; Molecular Docking Simulation; Molecular Structure; Pyrazoles; Pyrimidinones; Rats, Wistar; Structure-Activity Relationship; Triazoles | 2019 |
Novel oral transforming growth factor-β signaling inhibitor potently inhibits postsurgical adhesion band formation.
Topics: 3T3 Cells; Aniline Compounds; Animals; Apoptosis; Fibroblasts; Gene Expression Regulation; Inflammation; Mice; Oxidative Stress; Random Allocation; Tissue Adhesions; Transforming Growth Factor beta; Triazoles | 2020 |
Adenosine 2A receptor modulates inflammation and phenotype in experimental abdominal aortic aneurysms.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Aortic Aneurysm, Abdominal; CD4-Positive T-Lymphocytes; Cytokines; Humans; Inflammation; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Elastase; Phenethylamines; Phenotype; Receptors, Adenosine A2; Triazines; Triazoles | 2013 |
BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses.
Topics: Animals; Anti-Inflammatory Agents; Azepines; Bone Marrow Cells; Cell Line; Chromatin; Chromosomal Proteins, Non-Histone; Cytokines; Enzyme Activation; Gene Knockdown Techniques; Inflammation; Interferon-gamma; Lipopolysaccharides; Macrophages; Male; Mice; NF-kappa B; Nuclear Proteins; Promoter Regions, Genetic; Protein Binding; Protein Serine-Threonine Kinases; Transcription Factors; Triazoles | 2013 |
Targeted inhibition of Hsp90 by ganetespib is effective across a broad spectrum of breast cancer subtypes.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; HSP90 Heat-Shock Proteins; Humans; Inflammation; Mice, SCID; Molecular Targeted Therapy; Protein Stability; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Signal Transduction; Treatment Outcome; Triazoles; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2014 |
Inflammation and cognitive dysfunction in type 2 diabetic carotid endarterectomy patients.
Topics: Aged; Cognition Disorders; Diabetes Mellitus, Type 2; Endarterectomy, Carotid; Glyburide; Humans; Hypoglycemic Agents; Inflammation; Logistic Models; Metformin; Middle Aged; Pyrazines; Sitagliptin Phosphate; Sulfonylurea Compounds; Triazoles | 2013 |
Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: a role for A2A receptors.
Topics: Animals; Brain; Cannabidiol; Cardiovirus Infections; Cell Adhesion; Cells, Cultured; Chemokine CCL2; Chemokine CCL5; Disease Models, Animal; Endothelial Cells; Inflammation; Interleukin-1beta; Mice; Motor Activity; Multiple Sclerosis; Receptor, Adenosine A2A; Triazines; Triazoles; Vascular Cell Adhesion Molecule-1 | 2013 |
Preclinical characterization of GLPG0634, a selective inhibitor of JAK1, for the treatment of inflammatory diseases.
Topics: Animals; Cell Differentiation; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Gene Silencing; Humans; Inflammation; Inhibitory Concentration 50; Interleukin-6; Janus Kinase 1; Male; Mice; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Rats; STAT1 Transcription Factor; T-Lymphocytes, Helper-Inducer; Triazoles | 2013 |
The dipeptidyl peptidase-4 inhibitor-sitagliptin modulates calcium dysregulation, inflammation, and PPARs in hypertensive cardiomyocytes.
Topics: Action Potentials; Animals; Blood Pressure; Calcium; Cardiotonic Agents; Dipeptidyl-Peptidase IV Inhibitors; Electrocardiography; Heart Ventricles; Hypertension; Inflammation; Interleukin-6; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR delta; PPAR gamma; Pyrazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor for Advanced Glycation End Products; Receptor, Angiotensin, Type 1; Receptors, Immunologic; Sitagliptin Phosphate; Triazoles; Tumor Necrosis Factor-alpha | 2013 |
Exendin-4 and sitagliptin protect kidney from ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction.
Topics: Animals; Biomarkers; Creatinine; Exenatide; Inflammation; Kidney; Male; Oxidative Stress; Peptides; Proteinuria; Pyrazines; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reperfusion Injury; Sitagliptin Phosphate; Triazoles; Venoms | 2013 |
Regulation of NO synthesis, local inflammation, and innate immunity to pathogens by BET family proteins.
Topics: Animals; Azepines; Cells, Cultured; Chromosomal Proteins, Non-Histone; Gene Expression; Host-Pathogen Interactions; Immunity, Innate; Inflammation; Influenza A Virus, H1N1 Subtype; Listeria monocytogenes; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type II; Nuclear Proteins; Orthomyxoviridae Infections; Promoter Regions, Genetic; Protein Binding; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Survival Analysis; Transcription Factors; Triazoles | 2014 |
Cooperative role of endogenous leucotrienes and platelet-activating factor in ischaemia-reperfusion-mediated tissue injury.
Topics: Amidines; Animals; Azepines; Biological Assay; Carbamates; Dermis; Disease Models, Animal; Extravasation of Diagnostic and Therapeutic Materials; Extremities; Inflammation; Leukotriene B4; Leukotrienes; Male; Mice; Mice, Inbred C57BL; Myocardial Ischemia; Neutrophil Infiltration; Platelet Activating Factor; Platelet Membrane Glycoproteins; Propionates; Quinolines; Rabbits; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Reperfusion Injury; Triazoles | 2013 |
Potential anti-inflammatory effects of maraviroc in HIV-positive patients: a pilot study of inflammation, endothelial dysfunction, and coagulation markers.
Topics: Adult; Anti-Inflammatory Agents; Biomarkers; Case-Control Studies; CCR5 Receptor Antagonists; Cyclohexanes; Cytokines; Female; HIV Fusion Inhibitors; HIV Infections; Humans; Inflammation; Male; Maraviroc; Middle Aged; Pilot Projects; Thrombophilia; Triazoles | 2014 |
Brd4 is essential for IL-1β-induced inflammation in human airway epithelial cells.
Topics: Azepines; Cell Cycle Proteins; Cell Line; Chromatin Immunoprecipitation; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Hydrogen Peroxide; Inflammation; Interleukin-1beta; Interleukin-6; Interleukin-8; Nuclear Proteins; Protein Serine-Threonine Kinases; Transcription Factors; Triazoles | 2014 |
Dipeptidyl peptidase-IV inhibition prevents blood-retinal barrier breakdown, inflammation and neuronal cell death in the retina of type 1 diabetic rats.
Topics: Animals; Apoptosis; Biomarkers; Blood-Retinal Barrier; Blotting, Western; Cell Death; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Enzyme-Linked Immunosorbent Assay; Immunoenzyme Techniques; Inflammation; Male; Neurons; Pyrazines; Rats; Rats, Wistar; Retina; Sitagliptin Phosphate; Triazoles | 2014 |
Systemic inflammation regulates microglial responses to tissue damage in vivo.
Topics: Animals; Cell Culture Techniques; Cell Movement; Cerebral Cortex; Female; Immunologic Factors; Inflammation; Lasers; Lipopolysaccharides; Male; Mice, Transgenic; Microglia; Neuroimmunomodulation; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A3; Sepsis; Triazoles | 2014 |
Sitagliptin prevents inflammation and apoptotic cell death in the kidney of type 2 diabetic animals.
Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Glucagon-Like Peptide 1; Inflammation; Kidney; Pyrazines; Rats; Rats, Zucker; Sitagliptin Phosphate; Triazoles; Tumor Necrosis Factor-alpha | 2014 |
Synthesis of novel 2-mercaptobenzoxazole based 1,2,3-triazoles as inhibitors of proinflammatory cytokines and suppressors of COX-2 gene expression.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoxazoles; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytokines; Edema; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Inflammation; Mice; Models, Molecular; Pain; Rats; Rats, Wistar; Sulfhydryl Compounds; Triazoles; Tumor Cells, Cultured | 2014 |
Sitagliptin attenuates methionine/choline-deficient diet-induced steatohepatitis.
Topics: Animals; Biomarkers; Blotting, Western; Choline Deficiency; Diet; Dipeptidyl-Peptidase IV Inhibitors; Endoplasmic Reticulum Stress; Fatty Liver; Immunoenzyme Techniques; Inflammation; Lipid Peroxidation; Liver Cirrhosis; Male; Methionine; Mice; Mice, Inbred C57BL; NF-kappa B; Pyrazines; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sitagliptin Phosphate; Triazoles; Triglycerides | 2014 |
Iron homeostasis and infIammatory biomarker analysis in patients with type 1 Gaucher disease.
Topics: Adult; Aged; Benzoates; Biomarkers; Cytokines; Deferasirox; Deferoxamine; Female; Ferritins; Follow-Up Studies; Gaucher Disease; Hepcidins; Hexosaminidases; Homeostasis; Humans; Inflammation; Iron; Iron Chelating Agents; Iron Overload; Macrophage Activation; Macrophages; Male; Middle Aged; Quality of Life; Triazoles | 2014 |
NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis.
Topics: Acetylation; Animals; Atherosclerosis; Azepines; Cell Adhesion; Cell Movement; Cells, Cultured; Chromatin; E-Selectin; Endothelial Cells; Endothelium, Vascular; Enhancer Elements, Genetic; Histones; Humans; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B p50 Subunit; Nuclear Proteins; Protein Binding; Regulatory Sequences, Nucleic Acid; RNA Polymerase II; Signal Transduction; SOXF Transcription Factors; Transcription Factor RelA; Transcription Factors; Transcription Initiation, Genetic; Transcription, Genetic; Triazoles; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2014 |
Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1.
Topics: Anastrozole; Androstadienes; Animals; Aromatase Inhibitors; Behavior, Animal; Calcium; Calcium Channels; Cysteine; HEK293 Cells; Humans; Inflammation; Letrozole; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuropeptides; Nitriles; Pain; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Steroids; Transient Receptor Potential Channels; Triazoles; TRPA1 Cation Channel; TRPC Cation Channels | 2014 |
Dietary cholesterol directly induces acute inflammasome-dependent intestinal inflammation.
Topics: Animals; Benzoxazoles; Carrier Proteins; Caspase 1; Cholesterol, Dietary; Diet, High-Fat; Fatty Acids; Fatty Liver; Female; Immunity, Innate; Inflammasomes; Inflammation; Interleukin-1beta; Intestinal Mucosa; Intestines; Membrane Transport Proteins; Mice; Mice, Inbred BALB C; Myeloid Cells; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Triazoles; Zebrafish | 2014 |
Gliptin and GLP-1 analog treatment improves survival and vascular inflammation/dysfunction in animals with lipopolysaccharide-induced endotoxemia.
Topics: Animals; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Endotoxemia; Glucagon-Like Peptide 1; Inflammation; Linagliptin; Lipopolysaccharides; Liraglutide; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Purines; Pyrazines; Quinazolines; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Sitagliptin Phosphate; Triazoles | 2015 |
Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis.
Topics: Animals; Anti-Inflammatory Agents; Cell Survival; Cells, Cultured; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Embryonic Stem Cells; Endometriosis; Estrogens; Female; Fertility; Humans; Indazoles; Inflammation; Letrozole; Ligands; Macrophages; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Nitriles; Receptors, Estrogen; Stromal Cells; Treatment Outcome; Triazoles | 2015 |
HSP90 inhibition suppresses lipopolysaccharide-induced lung inflammation in vivo.
Topics: Animals; B-Lymphocytes; Benzoquinones; Cytokines; HSP90 Heat-Shock Proteins; Inflammation; Killer Cells, Natural; Lactams, Macrocyclic; Lipopolysaccharides; Lung; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Neutrophils; Triazoles | 2015 |
Expression of CD73 and A2A receptors in cells from subjects with obesity and type 2 diabetes mellitus.
Topics: 5'-Nucleotidase; Adenosine; Adult; Antigens, CD; Apoptosis; Apyrase; Body Mass Index; CD8-Positive T-Lymphocytes; Diabetes Mellitus, Type 2; Gene Expression Regulation; GPI-Linked Proteins; Humans; Inflammation; Lymphocyte Subsets; Lymphocytes; Obesity; Phenethylamines; Receptor, Adenosine A2A; Triazines; Triazoles | 2015 |
Novel thiazolo[3,2-b]-1,2,4-triazoles derived from naproxen with analgesic/anti-inflammatory properties: Synthesis, biological evaluation and molecular modeling studies.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; Drug Design; Edema; Humans; Inflammation; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Naproxen; Nociception; Pain; Pain Measurement; Structure-Activity Relationship; Thiazoles; Thiones; Triazoles | 2015 |
Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure.
Topics: Adenosine A2 Receptor Antagonists; Animals; Apoptosis; Glaucoma; Hydrostatic Pressure; Inflammation; Lipopolysaccharides; Models, Animal; Neuroprotective Agents; Nitric Oxide; Organ Culture Techniques; Pyrimidines; Rats; Rats, Wistar; Retinal Ganglion Cells; Triazoles | 2015 |
Imiquimod-induced psoriasis-like skin inflammation is suppressed by BET bromodomain inhibitor in mice through RORC/IL-17A pathway modulation.
Topics: Aminoquinolines; Animals; Azepines; Disease Models, Animal; Imiquimod; Inflammation; Interleukin-17; Interleukin-22; Interleukins; Male; Mice; Mice, Inbred BALB C; Nuclear Receptor Subfamily 1, Group F, Member 3; Psoriasis; Signal Transduction; Skin; Triazoles | 2015 |
BET Inhibition Upregulates SIRT1 and Alleviates Inflammatory Responses.
Topics: Animals; Azepines; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Epigenesis, Genetic; HEK293 Cells; Humans; Inflammation; MCF-7 Cells; Mice; Nuclear Proteins; Protein Serine-Threonine Kinases; RNA Interference; RNA, Small Interfering; Sirtuin 1; Transcription Factors; Triazoles; Up-Regulation | 2015 |
Alkaline phosphatase protects against renal inflammation through dephosphorylation of lipopolysaccharide and adenosine triphosphate.
Topics: Acute Kidney Injury; Adrenergic alpha-2 Receptor Antagonists; Alkaline Phosphatase; Animals; Cells, Cultured; Cytokines; Epithelial Cells; Fluoresceins; Gene Expression Regulation; Humans; Inflammation; Kidney; Lipopolysaccharides; Male; Oligosaccharides; Protective Agents; Purines; Rats, Sprague-Dawley; Recombinant Proteins; Triazines; Triazoles | 2015 |
Novel Triazolopyrimidine-Derived Cannabinoid Receptor 2 Agonists as Potential Treatment for Inflammatory Kidney Diseases.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cannabinoid Receptor Agonists; Dose-Response Relationship, Drug; Humans; Inflammation; Kidney Diseases; Models, Molecular; Molecular Structure; Pyrimidines; Receptor, Cannabinoid, CB2; Structure-Activity Relationship; Triazoles | 2016 |
Evaluation of the Effect of 1,3-Bis(4-Phenyl)-1H-1,2,3-Triazolyl-2-Propanolol on Gene Expression Levels of JAK2-STAT3, NF-κB, and SOCS3 in Cells Cultured from Biopsies of Mammary Lesions.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Cells, Cultured; Female; Gene Expression; Humans; Inflammation; Inhibitory Concentration 50; Janus Kinase 2; Middle Aged; NF-kappa B; Propranolol; Prospective Studies; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Triazoles | 2015 |
The Epigenetic Reader BRD2 as a Specific Modulator of PAI-1 Expression in Lipopolysaccharide-Stimulated Mouse Primary Astrocytes.
Topics: Animals; Astrocytes; Azepines; Chromosomal Proteins, Non-Histone; Cytokines; Epigenesis, Genetic; Gene Knockdown Techniques; Histones; Inflammation; Lipopolysaccharides; Mice; Nuclear Proteins; Primary Cell Culture; RNA, Messenger; RNA, Small Interfering; Serpin E2; Transcription Factors; Transfection; Triazoles | 2015 |
Dual transcriptome sequencing reveals resistance of TLR4 ligand-activated bone marrow-derived macrophages to inflammation mediated by the BET inhibitor JQ1.
Topics: Animals; Azepines; Bone Marrow Cells; Gene Expression Profiling; Gene Expression Regulation; Inflammation; Ligands; Lipopolysaccharides; Macrophages; Mice, Inbred C57BL; Molecular Sequence Annotation; Nuclear Proteins; Real-Time Polymerase Chain Reaction; Sequence Analysis, RNA; Toll-Like Receptor 4; Transcription Factors; Transcriptome; Triazoles | 2015 |
Inhibition of Dipeptidyl Peptidase-4 Impairs Ventricular Function and Promotes Cardiac Fibrosis in High Fat-Fed Diabetic Mice.
Topics: Animals; Cardiomegaly; Cytokines; Diabetes Mellitus, Experimental; Diet, High-Fat; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Fibrosis; Heart; Heart Failure; Hypoglycemic Agents; Immunoblotting; Inflammation; Liraglutide; Mice; Mice, Knockout; Myocardium; RNA, Messenger; Transcriptome; Triazoles; Ventricular Function; Ventricular Remodeling | 2016 |
A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation.
Topics: Animals; Arthritis, Experimental; Basophils; Cell Line; Collagen; Crystallography, X-Ray; Dose-Response Relationship, Drug; Edema; Eosinophils; Female; HEK293 Cells; Humans; Hypertension; Indazoles; Inflammation; Inhibitory Concentration 50; Intracellular Signaling Peptides and Proteins; Janus Kinase 2; Male; Neutropenia; Neutrophils; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Receptors, Fc; Skin; Syk Kinase; Triazoles; Vascular Endothelial Growth Factor Receptor-2 | 2016 |
Letrozole vs estradiol valerate induced PCOS in rats: glycemic, oxidative and inflammatory status assessment.
Topics: Animals; Antioxidants; Blood Glucose; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Estradiol; Female; Glycemic Index; Inflammation; Letrozole; Nitriles; Oxidative Stress; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Triazoles | 2016 |
Role of oxidative stress and low-grade inflammation in letrozole-induced polycystic ovary syndrome in the rat.
Topics: Animals; Aromatase Inhibitors; C-Reactive Protein; Female; Gene Expression Regulation; Inflammation; Letrozole; Lipid Peroxidation; Nitriles; Ovarian Follicle; Oxidative Stress; Polycystic Ovary Syndrome; Rats; Receptor, Insulin; Superoxide Dismutase; Testosterone; Triazoles | 2016 |
Inhibition of BET bromodomains alleviates inflammation in human RPE cells.
Topics: Anti-Inflammatory Agents; Azabicyclo Compounds; Azepines; Benzodiazepines; Carbazoles; Cell Line; Cell Survival; Epithelial Cells; Etoposide; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Interleukin-8; Models, Biological; NF-kappa B; Protein Domains; Pyridines; Retinal Pigment Epithelium; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Topoisomerase II Inhibitors; Transcription Factors; Triazoles; Tumor Suppressor Protein p53 | 2016 |
The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Azepines; Brain; Disease Models, Animal; Drug Evaluation, Preclinical; Inflammation; Learning; Male; Memory; Mice, Transgenic; Neuroprotective Agents; Organ Size; Peptide Fragments; Phosphorylation; Spleen; tau Proteins; Triazoles | 2016 |
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation.
Topics: Animals; Azepines; Camptothecin; DNA Topoisomerases, Type I; Ebolavirus; Flavonoids; Gene Expression Regulation; HEK293 Cells; Hemorrhagic Fever, Ebola; Host-Pathogen Interactions; Humans; Immunity, Innate; Inflammation; Influenza A virus; Interferon-beta; Mice; Mice, Inbred C57BL; Piperidines; Positive Transcriptional Elongation Factor B; RNA Polymerase II; Sendai virus; Staphylococcal Infections; Staphylococcus aureus; Topoisomerase I Inhibitors; Topotecan; Transcription, Genetic; Triazoles | 2016 |
Central leptin resistance and hypothalamic inflammation are involved in letrozole-induced polycystic ovary syndrome rats.
Topics: Animals; Body Weight; Eating; Female; Hypothalamus; Inflammation; Leptin; Letrozole; Nitriles; Ovary; Polycystic Ovary Syndrome; Rats, Sprague-Dawley; Suppressor of Cytokine Signaling 3 Protein; Triazoles | 2016 |
Rizatriptan overuse promotes hyperalgesia induced by dural inflammatory stimulation in rats by modulation of the serotonin system.
Topics: Animals; Cerebral Cortex; Headache Disorders, Secondary; Hyperalgesia; Inflammation; Male; Pain; Rats, Sprague-Dawley; Serotonin; Triazoles; Tryptamines | 2016 |
Highly specific blockade of CCR5 inhibits leukocyte trafficking and reduces mucosal inflammation in murine colitis.
Topics: Animals; CD11b Antigen; CD4-Positive T-Lymphocytes; Chemokine CCL5; Chemokines; Colitis; Colon; Cyclohexanes; Dextran Sulfate; Disease Models, Animal; Homeodomain Proteins; Inflammation; Intestinal Mucosa; Leukocytes; Maraviroc; Mice; Mice, Inbred C57BL; Mice, Knockout; Th17 Cells; Triazoles; Trinitrobenzenesulfonic Acid; Up-Regulation | 2016 |
Bromodomain and extra-terminal protein mimic JQ1 decreases inflammation in human vascular endothelial cells: Implications for pulmonary arterial hypertension.
Topics: Azepines; Cell Culture Techniques; Cell Proliferation; Down-Regulation; Endothelial Cells; Humans; Hypertension, Pulmonary; Inflammation; Interleukin-8; Lung; Microvessels; NF-kappa B; Proteins; Pulmonary Circulation; Triazoles; Vascular Remodeling | 2017 |
The suppression of bromodomain and extra-terminal domain inhibits vascular inflammation by blocking NF-κB and MAPK activation.
Topics: Azepines; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Inflammation; Mitogen-Activated Protein Kinases; NF-kappa B; Protein Kinase Inhibitors; Structure-Activity Relationship; Transcription Factors; Triazoles | 2017 |
Anastrozole-associated sclerosing glomerulonephritis in a patient with breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Atrophy; Breast Neoplasms; Fatal Outcome; Female; Glomerulosclerosis, Focal Segmental; Humans; Inflammation; Nitriles; Triazoles | 2007 |
Immune reconstitution syndrome after voriconazole treatment for cryptococcal meningitis in a liver transplant recipient.
Topics: Adrenal Cortex Hormones; Anti-Retroviral Agents; Antifungal Agents; Female; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Immune System; Inflammation; Liver Transplantation; Magnetic Resonance Imaging; Meningitis, Cryptococcal; Middle Aged; Pyrimidines; Recurrence; Triazoles; Voriconazole | 2008 |
Attenuation of gastric mucosal inflammation induced by indomethacin through activation of the A2A adenosine receptor in rats.
Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CXCL1; Dinoprostone; Gastric Mucosa; Indomethacin; Inflammation; Interleukin-1beta; Male; Peroxidase; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Stomach Ulcer; Triazines; Triazoles; Tumor Necrosis Factor-alpha | 2009 |
Regioselective reaction: synthesis and pharmacological study of Mannich bases containing ibuprofen moiety.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspergillus; Edema; Escherichia coli; Ibuprofen; Inflammation; Mannich Bases; Mice; Pain; Rats; Rats, Wistar; Schiff Bases; Staphylococcus aureus; Triazoles | 2009 |
Antioxidants vitamin E and 1-aminobenzotriazole prevent experimental non-alcoholic steatohepatitis in mice.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; bcl-2-Associated X Protein; Blotting, Western; Cyclooxygenase 2; Fatty Liver; Genes, bcl-2; Inflammation; Lipid Peroxidation; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; NF-kappa B p50 Subunit; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta1; Triazoles; Vitamin E | 2009 |
[A case of inflammatory breast cancer responding to anastrozole].
Topics: Adenocarcinoma, Scirrhous; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Inflammation; Nitriles; Receptors, Estrogen; Receptors, Progesterone; Triazoles | 2009 |
Activation of adenosine A2A receptor attenuates inflammatory response in a rat model of small-for-size liver transplantation.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Alanine Transaminase; Animals; Chemokine CXCL2; Cytokines; Enzyme-Linked Immunosorbent Assay; Inflammation; Intercellular Adhesion Molecule-1; Liver; Liver Transplantation; Male; NF-kappa B; Organ Size; Peroxidase; Phenethylamines; Phosphorylation; Rats; Rats, Inbred Lew; Receptor, Adenosine A2A; Triazines; Triazoles; Tumor Necrosis Factor-alpha | 2010 |
Peripheral adenosine A2A receptors are involved in carrageenan-induced mechanical hyperalgesia in mice.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Carrageenan; Female; Ganglia, Spinal; Hyperalgesia; Inflammation; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Mice, Knockout; Pain; Pain Threshold; Phenethylamines; Receptor, Adenosine A2A; Sex Characteristics; Triazines; Triazoles | 2010 |
Design, synthesis, and biological evaluation of 1,5-diaryl-1,2,4-triazole derivatives as selective cyclooxygenase-2 inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Celecoxib; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Drug Design; Inflammation; Inhibitory Concentration 50; Male; Mice; Protein Binding; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Triazoles | 2010 |
Dipeptidyl peptidase IV inhibitor sitagliptin reduces local inflammation in adipose tissue and in pancreatic islets of obese mice.
Topics: Adipocytes; Adipose Tissue; Adiposity; Animals; Anti-Inflammatory Agents; Body Weight; Cytokines; Dipeptidyl-Peptidase IV Inhibitors; Flow Cytometry; Glucose; Glucose Intolerance; Glucose Tolerance Test; Immunohistochemistry; Inflammation; Insulin; Islets of Langerhans; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Neutrophil Infiltration; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; Sitagliptin Phosphate; Triazoles | 2011 |
Effects of the new benzimidazole derivative TAS-203, an orally active phosphodiesterase 4 inhibitor, on airway inflammation in rats and emetic responses in ferrets.
Topics: Animals; Anti-Inflammatory Agents; Benzimidazoles; Chemotaxis, Leukocyte; Cloning, Molecular; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Ferrets; Guinea Pigs; Humans; Inflammation; Lipopolysaccharides; Male; Nitriles; Phosphodiesterase 4 Inhibitors; Platelet Activating Factor; Rats; Rats, Inbred BN; Rats, Inbred Lew; Respiratory Tract Diseases; Tissue Distribution; Triazoles; Tumor Necrosis Factor-alpha; Vomiting | 2010 |
Selective adenosine A2A receptor agonists and antagonists protect against spinal cord injury through peripheral and central effects.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Inflammation; Infusion Pumps, Implantable; JNK Mitogen-Activated Protein Kinases; Male; Mice; Motor Activity; Phenethylamines; Pyrimidines; Spinal Cord; Spinal Cord Injuries; Triazoles | 2011 |
The effect of A(2A) adenosine receptor activation on C-C chemokine receptor 7 expression in human THP1 macrophages during inflammation.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Cell Line; Cell Movement; Chemokine CCL21; Humans; Inflammation; Macrophages; Phenethylamines; Receptors, Adenosine A2; Receptors, CCR7; RNA, Messenger; Triazines; Triazoles | 2012 |
Modulatory effects of the CCR5 antagonist maraviroc on microglial pro-inflammatory activation elicited by gp120.
Topics: Animals; Blotting, Western; CCR5 Receptor Antagonists; Cell Survival; Cells, Cultured; Cyclohexanes; Cytokines; Dinoprostone; DNA Primers; HIV Envelope Protein gp120; HIV Infections; Inflammation; Interferon-gamma; Macrophage Activation; Maraviroc; Microglia; Nitric Oxide; Rats; Real-Time Polymerase Chain Reaction; RNA, Messenger; Triazoles | 2012 |
The effect of adenosine on pro-inflammatory cytokine production by porcine T cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Concanavalin A; Dose-Response Relationship, Drug; Flow Cytometry; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-2; Quinazolines; Swine; T-Lymphocyte Subsets; T-Lymphocytes; Triazoles; Tumor Necrosis Factor-alpha | 2012 |
Carboxyamidotriazole ameliorates experimental colitis by inhibition of cytokine production, nuclear factor-κB activation, and colonic fibrosis.
Topics: Animals; Colitis; Colon; Dextran Sulfate; Fibrosis; Inflammation; Inflammatory Bowel Diseases; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mucous Membrane; NF-kappa B; Phosphorylation; Proteolysis; Triazoles; Tumor Necrosis Factor-alpha | 2012 |
Discovery of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(tert-butyl)pyridine-3-sulfonamide (CZC24758), as a potent, orally bioavailable and selective inhibitor of PI3K for the treatment of inflammatory disease.
Topics: Animals; Drug Discovery; Granulocytes; Hydrogen Bonding; Inflammation; Male; Mice; Microsomes; Models, Molecular; Molecular Structure; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Rats; Structure-Activity Relationship; Sulfonamides; Triazoles | 2012 |
Sitagliptin exerts anti-inflammatory and anti-allergic effects in ovalbumin-induced murine model of allergic airway disease.
Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Inflammation; Lung; Male; Mice; Nitric Oxide Synthase Type II; Ovalbumin; Pyrazines; RNA, Messenger; Sitagliptin Phosphate; Triazoles | 2012 |
The effectiveness of liraglutide in nonalcoholic fatty liver disease patients with type 2 diabetes mellitus compared to sitagliptin and pioglitazone.
Topics: Adult; Alanine Transaminase; Blood Glucose; Body Weight; Comorbidity; Diabetes Mellitus, Type 2; Drug Evaluation; Drug Therapy, Combination; Fatty Liver; Female; Follow-Up Studies; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Inflammation; Liraglutide; Liver Cirrhosis; Logistic Models; Male; Middle Aged; Multivariate Analysis; Non-alcoholic Fatty Liver Disease; Odds Ratio; Pioglitazone; Platelet Count; Pyrazines; Retrospective Studies; Sitagliptin Phosphate; Thiazolidinediones; Treatment Outcome; Triazoles | 2012 |
DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Cytokines; Drug Discovery; Endocannabinoids; Glycerides; Inflammation; Lipid Metabolism; Lipoprotein Lipase; Macrophages, Peritoneal; Mice; Mice, Knockout; Neurons; Prostaglandins; Protein Isoforms; Proteome; Quantitative Structure-Activity Relationship; Signal Transduction; Triazoles; Tumor Necrosis Factor-alpha | 2012 |
Synthesis and anti-inflammatory activity of new alkyl-substituted phthalimide 1H-1,2,3-triazole derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Edema; Inflammation; Mice; Phthalimides; Triazoles | 2012 |
Maraviroc reduces cytokine expression and secretion in human adipose cells without altering adipogenic differentiation.
Topics: Adipocytes; Adipogenesis; Adipokines; Biomarkers; Cells, Cultured; Cyclohexanes; Cytokines; DNA, Mitochondrial; Gene Expression Regulation; Humans; Inflammation; Inflammation Mediators; Lipopolysaccharides; Maraviroc; Mitochondria; RNA, Messenger; Triazoles | 2013 |
Implication of hepatic transporters (MDR1 and MRP2) in inflammation-associated idiosyncratic drug-induced hepatotoxicity investigated by microvolume cytometry.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; Biological Transport; Chemical and Drug Induced Liver Injury; Flow Cytometry; Fluoroquinolones; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Inflammation; Ketolides; Lipopolysaccharides; Liver; Naphthyridines; Piperazines; Sulfonamides; Triazoles; Tumor Necrosis Factor-alpha; Xenobiotics | 2013 |
Platelet-activating factor antagonists decrease the inflammatory nociceptive response in rats.
Topics: Animals; Azepines; Diterpenes; Dose-Response Relationship, Drug; Formaldehyde; Ginkgolides; Inflammation; Lactones; Male; Pain; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thienopyridines; Time Factors; Triazoles | 2002 |
A small molecule inhibitor of redox-regulated NF-kappa B and activator protein-1 transcription blocks allergic airway inflammation in a mouse asthma model.
Topics: Administration, Intranasal; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Movement; Chemokine CCL11; Chemokines, CC; Disease Models, Animal; Eosinophils; Female; Humans; Inflammation; Interleukin-13; Lung; Mice; Mice, Inbred BALB C; Mucus; NF-kappa B; Ovalbumin; Oxidation-Reduction; Pyridazines; Thioredoxins; Transcription Factor AP-1; Triazoles; Tumor Cells, Cultured | 2002 |
Hemodynamic and proinflammatory actions of endothelin-1 in guinea pig small intestine submucosal microcirculation.
Topics: Animals; Azepines; Endothelin Receptor Antagonists; Endothelin-1; Guinea Pigs; Hemodynamics; Inflammation; Intestine, Small; Male; Microcirculation; Peptides, Cyclic; Receptors, Endothelin; Regional Blood Flow; Triazoles; Vasoconstriction | 2003 |
Antiplatelet properties of novel N-substituted-phenyl-1,2,3-triazole-4-acylhydrazone derivatives.
Topics: Animals; Female; Hydrazones; Inflammation; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Triazoles | 2003 |
HETEROCYCLIC STEROIDS IN THE ANTIINFLAMMATORY SERIES.
Topics: Anti-Inflammatory Agents; Chemistry, Pharmaceutical; Imidazoles; Inflammation; Pharmacology; Pyrazoles; Pyrimidines; Research; Steroids; Steroids, Heterocyclic; Thiazoles; Triazoles | 1964 |
T helper 1 inhibitor TAK-603 inhibits IFN-gamma and IL-12 production with no effect on IL-18: an observation in sarcoidosis patients.
Topics: Adult; Case-Control Studies; Female; Humans; Inflammation; Interferon-gamma; Interleukin-12; Interleukin-18; Leukocytes, Mononuclear; Male; Middle Aged; Quinolines; Sarcoidosis; T-Lymphocytes; Triazoles | 2004 |
Antiinflammatory and antiallodynic actions of the lignan niranthin isolated from Phyllanthus amarus. Evidence for interaction with platelet activating factor receptor.
Topics: Analgesics; Animals; Anisoles; Anti-Inflammatory Agents; Azepines; Binding, Competitive; Carrageenan; Cerebral Cortex; Dioxoles; Inflammation; Lignans; Male; Mice; Pain Measurement; Pain Threshold; Peroxidase; Phyllanthus; Plant Extracts; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pleurisy; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Tetrahydronaphthalenes; Time Factors; Triazoles | 2006 |
1,8-Naphthyridines VI. Synthesis and anti-inflammatory activity of 5-(alkylamino)-N,N-diethyl[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides with a new substitution pattern on the triazole ring.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Drug Design; Edema; Inflammation; Male; Naphthyridines; Rats; Rats, Sprague-Dawley; Triazoles | 2008 |
Delay of postnatal maturation sensitizes the mouse prostate to testosterone-induced pronounced hyperplasia: protective role of estrogen receptor-beta.
Topics: Animals; Aromatase Inhibitors; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Fulvestrant; Humans; Hyperplasia; Inflammation; Ki-67 Antigen; Male; Mice; Mice, Knockout; Nitriles; Phosphoproteins; Prolactin; Prostate; Receptors, Androgen; Receptors, LH; Receptors, Progesterone; Testosterone; Trans-Activators; Triazoles | 2007 |
Condensed bridgehead nitrogen heterocyclic system: synthesis and pharmacological activities of 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives of ibuprofen and biphenyl-4-yloxy acetic acid.
Topics: Acute Disease; Analgesics; Animals; Bacteria; Diphenylacetic Acids; Female; Fungi; Hepatocytes; Ibuprofen; Inflammation; Lipid Peroxidation; Male; Mice; Rats; Thiadiazoles; Triazoles; Ulcer | 2008 |
Functional evaluation of THIQ, a melanocortin 4 receptor agonist, in models of food intake and inflammation.
Topics: alpha-MSH; Animals; Anti-Inflammatory Agents; Body Weight; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Electron Spin Resonance Spectroscopy; Inflammation; Injections, Intraventricular; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Peptides, Cyclic; Rats; Rats, Wistar; Receptor, Melanocortin, Type 4; Tetrahydroisoquinolines; Triazoles | 2007 |
Reversal of pathological pain through specific spinal GABAA receptor subtypes.
Topics: Analgesics; Animals; Brain; Capsaicin; Chronic Disease; Diazepam; Disease Models, Animal; Fluorobenzenes; Formaldehyde; Ganglia, Spinal; Hot Temperature; Inflammation; Male; Mice; Neurons; Organ Specificity; Pain; Protein Isoforms; Protein Subunits; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Triazoles | 2008 |
Endothelin-induced contraction and mediator release in human bronchus.
Topics: Acetylcholine; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Bronchi; Dicarboxylic Acids; Endothelins; Fatty Acids, Unsaturated; Histamine Release; Humans; Hydrazines; In Vitro Techniques; Indomethacin; Inflammation; Leukotrienes; Lung; Meclofenamic Acid; Muscle Contraction; Muscle, Smooth; Platelet Aggregation Inhibitors; Prostaglandins; Spectrometry, Fluorescence; SRS-A; Thromboxane A2; Triazoles | 1993 |
Interleukin-1-induced leukocyte extravasation across rat mesenteric microvessels is mediated by platelet-activating factor.
Topics: Animals; Azepines; Cell Adhesion; Chemotaxis, Leukocyte; Dihydropyridines; Edema; Imidazoles; Inflammation; Interleukin-1; Leukocytes; Male; Mesentery; Microcirculation; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Recombinant Proteins; Skin; Triazoles | 1995 |
Hyperacute rejection in an ex vivo model of renal xenografting. Role of the mediator response and its pharmacologic manipulation by the specific platelet-activating factor antagonist WEB 2086BS.
Topics: Adult; Animals; Antibodies, Heterophile; Antibody Formation; Azepines; Female; Graft Rejection; Hematocrit; Hemoglobins; Humans; Inflammation; Kidney; Kidney Transplantation; Male; Perfusion; Platelet Activating Factor; Pressure; Prostaglandins; Swine; Transplantation, Heterologous; Triazoles; Tumor Necrosis Factor-alpha; Vascular Resistance | 1994 |
Inhibition of albumin denaturation and anti-inflammatory activity of acetamido [(phenyl-4'-yl)-oxymethyl)]2-(p-substituted phenylamino)-1,2,4-triazoles and -1,3,4-thiadiazoles.
Topics: Animals; Female; Inflammation; Male; Protein Denaturation; Rats; Serum Albumin, Bovine; Thiadiazoles; Triazoles | 1993 |
Role of PAF in the allergic pleurisy caused by ovalbumin in actively sensitized rats.
Topics: Analysis of Variance; Animals; Azepines; Chemotactic Factors, Eosinophil; Diterpenes; Drug Hypersensitivity; Eosinophils; Female; Freund's Adjuvant; Ginkgolides; Inflammation; Lactones; Leukocyte Count; Male; Oligopeptides; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleurisy; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles | 1993 |
Nitric oxide inhibits numerous features of mast cell-induced inflammation.
Topics: Animals; Azepines; Capillary Permeability; Cell Adhesion; Inflammation; Leukocytes; Male; Mast Cells; Nitric Oxide; p-Methoxy-N-methylphenethylamine; Rats; Rats, Sprague-Dawley; Triazoles | 1996 |
N-heteroaryl-2-phenyl-3-(benzyloxy)piperidines: a novel class of potent orally active human NK1 antagonists.
Topics: Animals; Biological Availability; Drug Stability; Ferrets; Guinea Pigs; Humans; Inflammation; Macaca mulatta; Male; Microsomes, Liver; Migraine Disorders; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Receptors, Neurokinin-1; Triazoles; Vomiting | 1996 |
Platelet-activating factor stimulates interleukin-6 production by human endothelial cells and synergizes with tumor necrosis factor for enhanced production of granulocyte-macrophage colony stimulating factor.
Topics: Azepines; Drug Synergism; Endothelium, Vascular; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Inflammation; Inflammation Mediators; Interleukin-6; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Triazoles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
The pharmacological profile of mouse hind paw inflammation induced by staphylococcal enterotoxin type A.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Azepines; Capsaicin; Cimetidine; Dexamethasone; Diphenhydramine; Edema; Enterotoxins; Enzyme Inhibitors; Hindlimb; Histamine Antagonists; Indomethacin; Inflammation; Male; Mice; Platelet Aggregation Inhibitors; Triazoles | 1997 |
The cytochrome P450 suicide inhibitor, 1-aminobenzotriazole, sensitizes rats to zymosan-induced toxicity.
Topics: Animals; Body Weight; Cytochrome P-450 Enzyme Inhibitors; Drug Synergism; Enzyme Inhibitors; Inflammation; Leukocyte Count; Male; Microsomes, Liver; Neutrophils; Nitrates; Nitrites; Organ Size; Rats; Rats, Sprague-Dawley; Survival Analysis; Triazoles; Zymosan | 1998 |
Induction of human neutrophil apoptosis by nitric oxide donors: evidence for a caspase-dependent, cyclic-GMP-independent, mechanism.
Topics: Adult; Apoptosis; Caspases; Cyclic GMP; Free Radicals; Guanylate Cyclase; Humans; In Vitro Techniques; Inflammation; Neutrophil Activation; Neutrophils; Nitric Oxide; Nitric Oxide Donors; Reactive Oxygen Species; Triazoles | 2000 |
Accelerated resequestration of cytosolic calcium and suppression of the pro-inflammatory activities of human neutrophils by CGS 21680 in vitro.
Topics: Adenosine; Calcium; Calcium Radioisotopes; Cyclic AMP; Cytosol; Dose-Response Relationship, Drug; Fura-2; Humans; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Antagonists; Superoxides; Thapsigargin; Triazines; Triazoles | 2000 |
Adenosine A(2A) receptor stimulation reduces inflammation and neointimal growth in a murine carotid ligation model.
Topics: Animals; Arteriosclerosis; Carotid Artery Injuries; Cell Adhesion Molecules; Female; Inflammation; Leukocyte Count; Macrophages; Mice; Mice, Inbred C57BL; Neutrophils; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazines; Triazoles | 2001 |
Effects of CGS 21680, a selective adenosine A2A receptor agonist, on allergic airways inflammation in the rat.
Topics: Adenosine; Allergens; Animals; Anti-Inflammatory Agents; Asthma; Blood Pressure; Budesonide; Dose-Response Relationship, Drug; Inflammation; Lung; Male; Ovalbumin; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred BN; Receptor, Adenosine A2A; Triazines; Triazoles; Vascular Resistance | 2002 |
Platelet-activating factor induces cell death in cultured astrocytes and oligodendrocytes: involvement of caspase-3.
Topics: Animals; Animals, Newborn; Antigens, Differentiation; Astrocytes; Azepines; Caspase 3; Caspases; Cell Death; Cells, Cultured; Central Nervous System; Diterpenes; Dose-Response Relationship, Drug; Free Radical Scavengers; Ginkgolides; Glial Fibrillary Acidic Protein; Inflammation; Lactones; Mice; Mice, Inbred CBA; Oligodendroglia; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Spinal Cord Injuries; Triazoles | 2002 |
Effects of inflammation on peroxisomal enzyme activities, catalase synthesis, and lipid metabolism.
Topics: Alcohol Oxidoreductases; Allylisopropylacetamide; Animals; Catalase; Chemical and Drug Induced Liver Injury; D-Amino-Acid Oxidase; Fatty Acids; Inflammation; Liver; Male; Microbodies; Nafenopin; Organoids; Oxidoreductases; Rats; Triazoles; Turpentine; Urate Oxidase | 1977 |
Platelet activating factor as a proinflammatory mediator in acetic-induced colitis in the rat.
Topics: Acetates; Animals; Azepines; Colitis; Inflammation; Platelet Activating Factor; Polyunsaturated Alkamides; Pyridines; Rats; Rats, Inbred Strains; Triazoles | 1991 |
A factor in serum lowers resistance and opens tight junctions of MDCK cells.
Topics: Animals; Azepines; Blood; Cell Line; Chromatography, Gel; Complement C3a; Complement C5a; Culture Media; Dogs; Humans; Inflammation; Intercellular Junctions; Kidney; Kinetics; Molecular Weight; Platelet Activating Factor; Serum Albumin; Triazoles | 1990 |
Pharmacological effects of SCH 30497--a novel analgesic substance.
Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nervous System; Drug Tolerance; Electroshock; Inflammation; Male; Mice; Narcotics; Pain; Prostaglandins; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Saimiri; Triazoles | 1985 |
[Application of benzotriazole for reduction of acute inflammatory reaction in experimental ocular chalcosis].
Topics: Acute Disease; Animals; Aqueous Humor; Copper; Eye Foreign Bodies; Inflammation; Rabbits; Triazoles | 1986 |
Immunological profile of DL111-IT, a new immunosuppressant agent.
Topics: Animals; Antibody Formation; Dose-Response Relationship, Drug; Hypersensitivity, Delayed; Immunosuppressive Agents; Inflammation; Lymphoma; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Triazoles | 1985 |