Compounds > triazoles
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triazoles and Infections, Plasmodium

triazoles has been researched along with Infections, Plasmodium in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.56)18.7374
1990's0 (0.00)18.2507
2000's1 (5.56)29.6817
2010's10 (55.56)24.3611
2020's6 (33.33)2.80

Authors

AuthorsStudies
Abramo, C; Capriles Goliatt, PVZ; David da Silva, A; de Azevedo Alves, L; Fazza Stroppa, PH; Marinho, JA; Reis Soares, R; Valério Lopes, F1
de Carvalho da Silva, F; de Carvalho, AS; Ferreira, VF; Graciano, IA1
Basilico, N; Belluti, F; Bisi, A; Gobbi, S; Legac, J; Parapini, S; Rampa, A; Seghetti, F1
Andrade, JL; Bueno, LL; Camara, CA; Costa Souza, RM; Dantas, WM; De Andrade-Neto, VF; De Medeiros Brito, RM; De Oliveira, RN; Ferreira, LKM; Fujiwara, RT; Montenegro Pimentel, LML; Pena, L; Pereira, VRA; Rathi, B; Santos, ACDS; Silva Junior, VA; Silva, CJO1
Hasbullah, SA; Hassan, NI; Rakesh, KP; Ravindar, L1
Cherkaoui, M; Dini, S; Gobeau, N; Kümmel, A; McCarthy, JS; Moehrle, JJ; Price, DJ; Simpson, JA; Zaloumis, SG1
Carvalho, I; Chierrito, TPC; de Andrade, P; Figueredo, AS; Mantoani, SP1
Booker, ML; Hartl, DL; Heidebrecht, R; Javier Gamo, F; Lafuente-Monasterio, MJ; Lukens, AK; Ross, LS; Wiegand, RC; Wirth, DF1
Blackie, MA; de Kock, C; Hamann, AR; Smith, PJ; van Otterlo, WA1
Angulo-Barturen, Í; Bahamontes-Rosa, N; Ballell-Pages, L; Berry, NG; Biagini, GA; Blackman, MJ; Calderón, F; Castañeda, P; Crespo, B; de Cózar, C; de Mercado, J; Fernández, J; Frigerio, M; Guijarro, L; Jiménez-Díaz, MB; Martínez-Martínez, MS; McConville, M; Nixon, GL; O'Neill, PM; Santos-Villarejo, Á; Sanz, LM; Ward, SA; Washbourn, G1
Baldwin, J; Buckner, FS; Charman, S; Charman, WN; Creason, S; El Mazouni, F; Gujjar, R; Marwaha, A; Phillips, MA; Rathod, PK; Shackleford, DM; White, J; White, KL1
Benicewicz, DB; Chen, PC; Gryder, B; Guerrant, W; Khan, SI; Oyelere, AK; Patil, V; Tekwani, BL1
Ojha, PK; Roy, K1
Bathurst, I; Buckner, FS; Burrows, J; Charman, SA; Charman, WN; Creason, S; Deng, X; El Mazouni, F; Floyd, DM; Gujjar, R; Matthews, D; Phillips, MA; Rathod, PK; Shackleford, DM; White, J; White, KL1
Cortopassi, WA; França, TC; Krettli, AU; Oliveira, AA; Penna-Coutinho, J1
Berger, O; Biagini, GA; Bray, PG; Kaniti, A; O'Neill, PM; van Ba, CT; Vial, H; Ward, SA1
Bathurst, I; Craft, JC; Ekland, E; Fernandes, P; Fidock, DA; Lotharius, J; Wittlin, S1
McGregor, S; Ryley, JF; Wilson, RG1

Reviews

3 review(s) available for triazoles and Infections, Plasmodium

ArticleYear
1,2,3-Triazole- and Quinoline-based Hybrids with Potent Antiplasmodial Activity.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2022, Volume: 18, Issue:5

    Topics: Antimalarials; Humans; Malaria; Plasmodium falciparum; Quinolines; Triazoles

2022
Triazole hybrid compounds: A new frontier in malaria treatment.
    European journal of medicinal chemistry, 2023, Nov-05, Volume: 259

    Topics: Antimalarials; Humans; Malaria; Malaria, Falciparum; Plasmodium; Plasmodium falciparum; Triazoles

2023
Potential Triazole-based Molecules for the Treatment of Neglected Diseases.
    Current medicinal chemistry, 2019, Volume: 26, Issue:23

    Topics: Animals; Antiprotozoal Agents; Chagas Disease; Humans; Leishmaniasis; Malaria; Triazoles; Tuberculosis

2019

Other Studies

15 other study(ies) available for triazoles and Infections, Plasmodium

ArticleYear
1,2,3-Triazole derivatives: synthesis, docking, cytotoxicity analysis and in vivo antimalarial activity.
    Chemico-biological interactions, 2021, Dec-01, Volume: 350

    Topics: Animals; Antimalarials; Catalytic Domain; Computer Simulation; Drug Evaluation, Preclinical; Female; Hemolysis; Humans; L-Lactate Dehydrogenase; Macrophages, Peritoneal; Malaria; Mice; Molecular Docking Simulation; Plasmodium berghei; Protein Structure, Quaternary; Protozoan Proteins; Structure-Activity Relationship; Triazoles

2021
Hitting drug-resistant malaria infection with triazole-linked flavonoid-chloroquine hybrid compounds.
    Future medicinal chemistry, 2022, Volume: 14, Issue:24

    Topics: Antimalarials; Chloroquine; Flavonoids; Humans; Malaria; Plasmodium falciparum; Triazoles

2022
Biological activity of 1,2,3-triazole-2-amino-1,4-naphthoquinone derivatives and their evaluation as therapeutic strategy for malaria control.
    European journal of medicinal chemistry, 2023, Jul-05, Volume: 255

    Topics: Animals; Antimalarials; Chlorocebus aethiops; Humans; Malaria; Malaria, Falciparum; Mammals; Mice; Naphthoquinones; Plasmodium berghei; Plasmodium falciparum; Triazoles; Vero Cells

2023
Seeking an optimal dosing regimen for OZ439/DSM265 combination therapy for treating uncomplicated falciparum malaria.
    The Journal of antimicrobial chemotherapy, 2021, 08-12, Volume: 76, Issue:9

    Topics: Antimalarials; Bayes Theorem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Pyrimidines; Triazoles

2021
Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Jan-14, Volume: 111, Issue:2

    Topics: Analysis of Variance; Base Sequence; Chloroquine; Dihydroorotate Dehydrogenase; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Genetic Fitness; Genome; Malaria; Molecular Sequence Data; Oxidoreductases Acting on CH-CH Group Donors; Plasmodium falciparum; Point Mutation; Pyrimidines; Sequence Analysis, DNA; Small Molecule Libraries; Triazoles

2014
Synthesis of novel triazole-linked mefloquine derivatives: biological evaluation against Plasmodium falciparum.
    Bioorganic & medicinal chemistry letters, 2014, Dec-01, Volume: 24, Issue:23

    Topics: Antimalarials; Humans; Malaria; Mefloquine; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Triazoles

2014
Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials.
    Journal of medicinal chemistry, 2015, Aug-27, Volume: 58, Issue:16

    Topics: Animals; Antimalarials; High-Throughput Screening Assays; Humans; In Vitro Techniques; Malaria; Malaria, Falciparum; Mice; Mice, SCID; Microsomes, Liver; Plasmodium berghei; Plasmodium falciparum; Serine Proteinase Inhibitors; Structure-Activity Relationship; Triazoles

2015
Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice.
    Journal of medicinal chemistry, 2009, Apr-09, Volume: 52, Issue:7

    Topics: Administration, Oral; Animals; Antimalarials; Dihydroorotate Dehydrogenase; Humans; In Vitro Techniques; Malaria; Male; Mice; Microsomes, Liver; Models, Molecular; Oxidoreductases Acting on CH-CH Group Donors; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship; Thiazoles; Triazoles

2009
Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Antimalarials; Antiprotozoal Agents; Histone Deacetylase Inhibitors; Histone Deacetylases; Leishmania donovani; Leishmaniasis; Malaria; Plasmodium falciparum; Structure-Activity Relationship; Triazoles

2010
Chemometric modeling, docking and in silico design of triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors as antimalarials.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:10

    Topics: Antimalarials; Dihydroorotate Dehydrogenase; Drug Design; Enzyme Inhibitors; Humans; Malaria; Models, Biological; Models, Molecular; Oxidoreductases Acting on CH-CH Group Donors; Plasmodium; Pyrimidines; Quantitative Structure-Activity Relationship; Triazoles

2010
Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice.
    Journal of medicinal chemistry, 2011, Jun-09, Volume: 54, Issue:11

    Topics: Animals; Antimalarials; Dihydroorotate Dehydrogenase; Disease Models, Animal; Drug Design; Drug Discovery; Enzyme Inhibitors; Humans; Malaria; Mice; Microsomes, Liver; Molecular Structure; Oxidoreductases Acting on CH-CH Group Donors; Plasmodium berghei; Plasmodium falciparum; Protein Binding; Pyrimidines; Solubility; Structure-Activity Relationship; Triazoles

2011
Antimalarial activity of potential inhibitors of Plasmodium falciparum lactate dehydrogenase enzyme selected by docking studies.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: Animals; Antimalarials; Atorvastatin; Catalytic Domain; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Itraconazole; L-Lactate Dehydrogenase; Malaria; Mice; Plasmodium falciparum; Pyrroles; Triazoles

2011
Synthesis and antimalarial activities of a diverse set of triazole-containing furamidine analogues.
    ChemMedChem, 2011, Nov-04, Volume: 6, Issue:11

    Topics: Animals; Antimalarials; Benzamidines; Click Chemistry; Drug Evaluation, Preclinical; Female; Hemeproteins; Malaria; Mice; Plasmodium falciparum; Triazoles

2011
In vitro and in vivo activity of solithromycin (CEM-101) against Plasmodium species.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:2

    Topics: Animals; Antimalarials; Drug Resistance, Multiple; Humans; Macrolides; Malaria; Mice; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Triazoles

2012
Activity of ICI 195,739--a novel, orally active bistriazole--in rodent models of fungal and protozoal infections.
    Annals of the New York Academy of Sciences, 1988, Volume: 544

    Topics: Animals; Antifungal Agents; Antiprotozoal Agents; Candidiasis, Vulvovaginal; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Malaria; Mice; Rats; Structure-Activity Relationship; Tinea; Triazoles; Trypanosomiasis

1988