Page last updated: 2024-08-24

triazoles and Hyperuricemia

triazoles has been researched along with Hyperuricemia in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's23 (79.31)24.3611
2020's6 (20.69)2.80

Authors

AuthorsStudies
Saeed Alghamdi, Y1
Guo, S; Hu, SS; Lu, PF; Meng, FH; Wang, ZR; Zhang, TJ; Zhang, X; Zhang, Y; Zhang, ZH1
Cheng, H; Hou, X; Li, X; Nan, G; Ren, L; Tian, J; Xiao, Z; Yan, D; Yang, Y; Ye, F1
Oyagüez, I; Pérez-Ruiz, F; Presa, M1
Alghamdi, YS; Nassan, MA; Soliman, MM1
Chen, TT; Cheng, FM; Lin, CC; Tien, JZ; Yeh, SP1
Borghi, C; Cicero, AFG; Fogacci, F; Kuwabara, M1
Deeks, ED1
Cao, Y; Chen, J; Dong, S; Fu, W; Li, H; Pang, J; Tian, Y; Wu, T; Xi, B; Zhou, P1
Dalbeth, N; Robinson, PC1
Aksenov, S; Eriksson, UG; Peck, CC; Stanski, DR1
Basile, M; Cicchetti, A; Drago, C; Rolli, FR; Ruggeri, M1
Gillen, M; Hall, J; Ito, Y; Liu, S; Shen, Z; Shiramoto, M; Yamamoto, A; Yan, X1
Chang, YS; Chang, YT; Lee, CH; Lin, YC; Loh, EW; Tam, KW; Wu, JY; Wu, MY1
Robinson, PC1
Liu, YQ; Wang, RL; Wu, JW; Xie, YF; Yin, L; Zhang, H; Zhao, GL1
Gupta, MK; Singh, JA1
Ammirabile, M; Casale, M; Cinque, P; Costantini, S; Di Matola, T; Filosa, A; Prossomariti, L; Ricchi, P; Spasiano, A1
Baumgartner, S; Fleischmann, R; Hingorani, V; Kerr, B; Manhard, K; Miner, JN; Polvent, E; Quart, B; Shen, Z; Suster, M; Yeh, LT1
Jansen, TL1
Diaz-Torné, C; Perez-Herrero, N; Perez-Ruiz, F1
Hoy, SM1
Bromberg, DJ; Nanjappa, S; Pabbathi, S; Valenzuela, M1
Schulze-Koops, H; Witt, M1
Liu, W; Liu, Y; Shang, Q; Tang, L; Wang, J; Wu, J; Xie, Y; Xu, W; Zhang, X; Zhao, G; Zhou, Z1
Bucci, G; Gillen, M; Kerr, B; Lee, C; Shen, Z; Tieu, K; Wilson, D1
Agapidou, A; Economou, M; Efthimia, V; Neokleous, N; Perifanis, V; Teli, A; Vetsiou, E1

Reviews

9 review(s) available for triazoles and Hyperuricemia

ArticleYear
Therapeutic Strategies for the Treatment of Chronic Hyperuricemia: An Evidence-Based Update.
    Medicina (Kaunas, Lithuania), 2021, Jan-10, Volume: 57, Issue:1

    Topics: Acetamides; Allopurinol; Benzbromarone; Chronic Disease; Evidence-Based Medicine; Febuxostat; Gout Suppressants; Humans; Hyperuricemia; Naphthalenes; Nitriles; Phenylacetates; Polyethylene Glycols; Probenecid; Propionates; Pyridines; Thioglycolates; Triazoles; Urate Oxidase; Uricosuric Agents; Xanthine Oxidase

2021
Lesinurad: A Review in Hyperuricaemia of Gout.
    Drugs & aging, 2017, Volume: 34, Issue:5

    Topics: Adult; Allopurinol; Drug Therapy, Combination; Enzyme Inhibitors; Febuxostat; Gout; Humans; Hyperuricemia; Kidney; Middle Aged; Organic Anion Transporters; Organic Cation Transport Proteins; Thioglycolates; Treatment Outcome; Triazoles; Uric Acid; Uricosuric Agents; Xanthine Oxidase

2017
Efficacy and Safety of Lesinurad in Patients with Hyperuricemia Associated with Gout: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Pharmacotherapy, 2018, Volume: 38, Issue:11

    Topics: Gout; Humans; Hyperuricemia; Randomized Controlled Trials as Topic; Thioglycolates; Triazoles; Uricosuric Agents

2018
Gout - An update of aetiology, genetics, co-morbidities and management.
    Maturitas, 2018, Volume: 118

    Topics: Allopurinol; Chronic Disease; Comorbidity; Diet; Febuxostat; Gout; Gout Suppressants; Humans; Hyperuricemia; Probenecid; Thioglycolates; Triazoles; Uric Acid

2018
Cardiovascular Disease in Gout and the Protective Effect of Treatments Including Urate-Lowering Therapy.
    Drugs, 2019, Volume: 79, Issue:5

    Topics: Allopurinol; Anti-Inflammatory Agents; Cardiovascular Diseases; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Thioglycolates; Treatment Outcome; Triazoles; Uric Acid

2019
New medications in development for the treatment of hyperuricemia of gout.
    Current opinion in rheumatology, 2015, Volume: 27, Issue:2

    Topics: Acetamides; Drug Design; Gout; Gout Suppressants; Humans; Hyperuricemia; Imino Furanoses; Molecular Targeted Therapy; Phenylacetates; Pyrimidinones; Thioglycolates; Triazoles; Uricosuric Agents

2015
Lesinurad: First Global Approval.
    Drugs, 2016, Volume: 76, Issue:4

    Topics: Clinical Trials as Topic; Enzyme Inhibitors; Gout; Humans; Hyperuricemia; Thioglycolates; Triazoles; Uricosuric Agents; Xanthine Oxidase

2016
[Hyperuricemia and gout : New aspects of an old disease].
    Der Internist, 2016, Volume: 57, Issue:7

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Gouty; Diagnosis, Differential; Evidence-Based Medicine; Gout Suppressants; Humans; Hyperuricemia; Radiography, Dual-Energy Scanned Projection; Thioglycolates; Treatment Outcome; Triazoles; Uricosuric Agents

2016
Lesinurad (Zurampic) for gout-associated hyperuricemia.
    The Medical letter on drugs and therapeutics, 2016, Nov-21, Volume: 58, Issue:1508

    Topics: Clinical Trials as Topic; Gout; Humans; Hyperuricemia; Thioglycolates; Triazoles; Uricosuric Agents; Xanthine Oxidase

2016

Trials

3 trial(s) available for triazoles and Hyperuricemia

ArticleYear
Lesinurad for the treatment of hyperuricaemia in people with gout.
    Expert opinion on pharmacotherapy, 2017, Volume: 18, Issue:17

    Topics: Animals; Gout; Gout Suppressants; Haplorhini; Humans; Hyperuricemia; Thioglycolates; Triazoles

2017
Verinurad combined with febuxostat in Japanese adults with gout or asymptomatic hyperuricaemia: a phase 2a, open-label study.
    Rheumatology (Oxford, England), 2018, 09-01, Volume: 57, Issue:9

    Topics: Administration, Oral; Adult; Aged; Benzbromarone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Febuxostat; Female; Follow-Up Studies; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Organic Anion Transporters; Organic Cation Transport Proteins; Thioglycolates; Time Factors; Treatment Outcome; Triazoles; Uric Acid; Uricosuric Agents; Young Adult

2018
Pharmacodynamic, pharmacokinetic and tolerability evaluation of concomitant administration of lesinurad and febuxostat in gout patients with hyperuricaemia.
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:12

    Topics: Adult; Aged; Colchicine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Thiazoles; Thioglycolates; Triazoles; Uric Acid

2014

Other Studies

17 other study(ies) available for triazoles and Hyperuricemia

ArticleYear
Hepatic and Renal Impacts of Lesinurad on Experimental Hyperuricemia: Biochemical, Molecular and Pathological Investigations.
    Pakistan journal of biological sciences : PJBS, 2021, Volume: 24, Issue:7

    Topics: Animals; Humans; Hyperuricemia; Kidney; Liver; Male; Mice; Thioglycolates; Triazoles; Uricosuric Agents

2021
Discovery of 4-(phenoxymethyl)-1H-1,2,3-triazole derivatives as novel xanthine oxidase inhibitors.
    Bioorganic & medicinal chemistry letters, 2022, 03-15, Volume: 60

    Topics: Animals; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Hyperuricemia; Ligands; Models, Molecular; Molecular Structure; Oxonic Acid; Rats; Structure-Activity Relationship; Triazoles; Uric Acid; Xanthine Oxidase

2022
Discovery of novel 1,2,4-triazole derivatives as xanthine oxidoreductase inhibitors with hypouricemic effects.
    Bioorganic chemistry, 2022, Volume: 129

    Topics: Animals; Enzyme Inhibitors; Febuxostat; Gout; Hyperuricemia; Mice; Triazoles; Xanthine Dehydrogenase; Xanthine Oxidase

2022
Second-line treatment with lesinurad and allopurinol versus febuxostat for management of hyperuricemia: a cost-effectiveness analysis for Spanish patients.
    Clinical rheumatology, 2019, Volume: 38, Issue:12

    Topics: Allopurinol; Cost-Benefit Analysis; Febuxostat; Gout Suppressants; Humans; Hyperuricemia; Markov Chains; Spain; Thioglycolates; Triazoles

2019
Impact of Lesinurad and allopurinol on experimental Hyperuricemia in mice: biochemical, molecular and Immunohistochemical study.
    BMC pharmacology & toxicology, 2020, 02-10, Volume: 21, Issue:1

    Topics: Allopurinol; Animals; Blood Urea Nitrogen; Catalase; Drug Synergism; Glutathione Peroxidase; Gout Suppressants; Hyperuricemia; Interleukin-1beta; Kidney; Liver; Male; Mice; Thioglycolates; Triazoles; Tumor Necrosis Factor-alpha; Uric Acid; Xanthine Oxidase

2020
Venetoclax plus cytochrome P450 inhibitors without ramp-up strategy led to low risk of tumor lysis syndrome in acute myeloid leukemia.
    Annals of hematology, 2020, Volume: 99, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Child; Creatinine; Cytochrome P-450 Enzyme Inhibitors; Drug Administration Schedule; Drug Synergism; Female; Humans; Hyperuricemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Sulfonamides; Triazoles; Tumor Lysis Syndrome; Urate Oxidase; Uric Acid; Young Adult

2020
Identification and characterization of a potent and selective inhibitor of human urate transporter 1.
    Pharmacological reports : PR, 2017, Volume: 69, Issue:5

    Topics: Animals; Blood Urea Nitrogen; Cell Line; Cell Survival; Creatinine; Dogs; Humans; Hyperuricemia; Molecular Structure; Organic Anion Transporters; Organic Cation Transport Proteins; Rats; Thioglycolates; Triazoles

2017
Lesinurad/Allopurinol (Duzallo) for Gout-Associated Hyperuricemia.
    JAMA, 2018, 01-09, Volume: 319, Issue:2

    Topics: Allopurinol; Drug Combinations; Drug Interactions; Gout; Gout Suppressants; Humans; Hyperuricemia; Organic Anion Transporters; Organic Cation Transport Proteins; Thioglycolates; Triazoles; Xanthine Oxidase

2018
Individualized treatment strategies for hyperuricemia informed by a semi-mechanistic exposure-response model of uric acid dynamics.
    Physiological reports, 2018, Volume: 6, Issue:5

    Topics: Allopurinol; Clinical Trials as Topic; Febuxostat; Humans; Hyperuricemia; Models, Theoretical; Precision Medicine; Thioglycolates; Triazoles; Uric Acid; Uricosuric Agents

2018
Cost-Effectiveness Analysis of Lesinurad/Allopurinol Versus Febuxostat for the Management of Gout/Hyperuricemia in Italy.
    PharmacoEconomics, 2018, Volume: 36, Issue:5

    Topics: Allopurinol; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Italy; Male; Markov Chains; Middle Aged; Models, Economic; Monte Carlo Method; Quality-Adjusted Life Years; Thioglycolates; Triazoles

2018
Synthesis, biological evaluation and 3D-QSAR studies of 1,2,4-triazole-5-substituted carboxylic acid bioisosteres as uric acid transporter 1 (URAT1) inhibitors for the treatment of hyperuricemia associated with gout.
    Bioorganic & medicinal chemistry letters, 2019, 02-01, Volume: 29, Issue:3

    Topics: Carboxylic Acids; Dose-Response Relationship, Drug; Esters; Gout; Humans; Hyperuricemia; Molecular Structure; Organic Anion Transporters; Organic Cation Transport Proteins; Quantitative Structure-Activity Relationship; Triazoles

2019
Nephrolithiasis in patients exposed to deferasirox and desferioxamine: probably an age-linked event with different effects on some renal parameters.
    Annals of hematology, 2014, Volume: 93, Issue:3

    Topics: Adult; Aging; Benzoates; beta-Thalassemia; Chelation Therapy; Deferasirox; Deferoxamine; Disease Susceptibility; Female; Glomerular Filtration Rate; Humans; Hyperuricemia; Incidence; Iron Chelating Agents; Iron Overload; Italy; Kidney; Male; Nephrolithiasis; Retrospective Studies; Transfusion Reaction; Triazoles; Ultrasonography

2014
Treat to target in gout by combining two modes of action.
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:12

    Topics: Febuxostat; Female; Gout; Gout Suppressants; Humans; Hyperuricemia; Male; Thiazoles; Thioglycolates; Triazoles

2014
Hyperuricemia in 2 Patients Receiving Palbociclib for Breast Cancer.
    Cancer control : journal of the Moffitt Cancer Center, 2016, Volume: 23, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease-Free Survival; Female; Humans; Hyperuricemia; Letrozole; Nitriles; Piperazines; Protein Kinase Inhibitors; Pyridines; Receptor, ErbB-2; Receptors, Estrogen; Retrospective Studies; Triazoles

2016
Discovery of Flexible Naphthyltriazolylmethane-based Thioacetic Acids as Highly Active Uric Acid Transporter 1 (URAT1) Inhibitors for the Treatment of Hyperuricemia of Gout.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2017, Volume: 13, Issue:3

    Topics: Dose-Response Relationship, Drug; Drug Discovery; Gout; HEK293 Cells; Humans; Hyperuricemia; Molecular Structure; Organic Anion Transporters; Organic Cation Transport Proteins; Structure-Activity Relationship; Sulfhydryl Compounds; Triazoles

2017
Evaluation of Pharmacokinetic Interactions Between Lesinurad, a New Selective Urate Reabsorption Inhibitor, and Commonly Used Drugs for Gout Treatment.
    Clinical pharmacology in drug development, 2017, Volume: 6, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Colchicine; Drug Administration Schedule; Drug Interactions; Female; Gout Suppressants; Humans; Hyperuricemia; Indomethacin; Male; Middle Aged; Naproxen; Thioglycolates; Treatment Outcome; Triazoles; Uricosuric Agents; Young Adult

2017
Nephrolithiasis in beta thalassemia major patients treated with deferasirox: an advent or an adverse event? A single Greek center experience.
    Annals of hematology, 2013, Volume: 92, Issue:2

    Topics: Adult; Benzoates; beta-Thalassemia; Chelation Therapy; Child; Child, Preschool; Deferasirox; Deferiprone; Female; Greece; Humans; Hypercalciuria; Hyperuricemia; Iron Chelating Agents; Iron Overload; Male; Nephrolithiasis; Postoperative Complications; Pyridones; Splenectomy; Transfusion Reaction; Triazoles; Young Adult

2013