Page last updated: 2024-08-24

triazoles and HIV Infections

triazoles has been researched along with HIV Infections in 546 studies

Research

Studies (546)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (0.92)18.2507
2000's131 (23.99)29.6817
2010's356 (65.20)24.3611
2020's54 (9.89)2.80

Authors

AuthorsStudies
Challenger, E; Else, L; Imaz, A; Khoo, S; Niubó, J; Penchala, SD; Podzamczer, D; Prieto, P; Rigo-Bonin, R; Saumoy, M; Scévola, S; Silva-Klug, A; Soriano, I; Tiraboschi, J1
Appiah-Kubi, P; Iwuchukwu, EA; Soliman, MES1
Asante-Appiah, E; Grobler, JA; Hazuda, D; Lai, J; Martin, EA; Petropoulos, CJ; Sklar, P; Walworth, C; Wan, H; Yang, D1
Canziani, GA; Chaiken, IM; Dick, A; Enríquez Rodríguez, L; Holmes, AP; Rashad, AA; Root, MJ; Zhang, S1
Akari, H; Irie, K; Kikumori, M; Murata, M; Seki, Y; Tan, W; Tang, Y; Wardani, NP; Washizaki, A1
Khoo, S; Stockdale, AJ1
Antinori, S; Baldelli, S; Bisinella, GC; Cattaneo, D; Cossu, MV; Fusi, M; Gervasoni, C; Meraviglia, P; Micheli, V; Resnati, C; Vimercati, S1
Cattelan, AM; Leoni, D; Mazzitelli, M; Putaggio, C; Sasset, L1
Cai, W; Chen, M; Lan, G; Lan, Y; Liang, S; Ma, Y; Ni, M; Sun, Z; Wang, J; Yan, L; Yu, F; Zhang, F; Zhang, H; Zhang, X1
Bailón, L; Curran, A; Else, L; Graterol, F; Imaz, A; Khoo, S; Moltó, J; Paredes, R; Pérez, F; Ramos, N; Sandoval, D1
Bociąga-Jasik, M; Hlebowicz, M; Jakubowski, P; Parczewski, M; Raczyńska, A; Scheibe, K; Szetela, B; Szymczak, A; Urbańska, A; Łojewski, W1
Carrozzo, G; Cattaneo, D; Gervasoni, C; Poloni, A; Riva, A1
G Ang, C; M Chaiken, I; P Carter, E1
Antoni, MD; Castelli, F; Cattelan, AM; Fabbiani, M; Ferraresi, A; Lapadula, G; Mazzitelli, M; Putaggio, C; Quiros-Roldan, E; Ripamonti, D; Zuglian, G1
Afani Saud, A; Bettacchi, C; Chahin Anania, C; Correll, T; Eves, K; Grandhi, A; Hanna, GJ; Hepler, D; Hwang, C; Klopfer, SO; Molina, JM; Robertson, MN; Yazdanpanah, Y1
Chen, H; Chen, L; Li, J; Liu, H; Luo, RH; Ma, D; Peng, P; Wang, J; Xie, X; Yang, LM; Zhang, S; Zheng, CB; Zheng, YG; Zheng, YT1
Bolzenius, J; Chow, D; Clements, DM; De Gruttola, V; Kallianpur, K; Matos, M; Ndhlovu, LC; Paul, R; Premeaux, TA; Rodriguez-Benitez, RJ; Shikuma, CM; Shiramizu, B; Siriwardhana, C; Souza, SA; Turner, EH; Wojna, V1
Blevins, SR; Chastain, DB; Cluck, DB; Hester, EK1
Badshah, C; DeJesus, E; Goldstein, D; Hanna, GJ; Hepler, D; Hwang, C; Johnson, M; Kumar, S; Mallolas, J; Molina, JM; Pozniak, A; Rodgers, A; Sklar, P; Teal, V; Teppler, H; Wong, A1
Hazuda, D; Hwang, C; Lai, MT1
Grobler, JA; Markowitz, M1
Cahn, P; DeJesus, E; Hanna, GJ; Hwang, C; Kumar, S; Lai, MT; Lombaard, J; Lupinacci, L; Martin, EA; Molina, JM; Rodgers, A; Sax, PE; Sklar, P; Squires, K1
Abdi, B; Andreoni, M; Antinori, A; Armenia, D; Bertoli, A; Calvez, V; Ceccherini-Silberstein, F; Charpentier, C; Descamps, D; Forbici, F; Gennari, W; Jary, A; Marcelin, AG; Mussini, C; Perno, CF; Santoro, MM; Soulie, C; Storto, A1
Aguilera, A; Alejos, B; Álvarez, M; Blanco, JR; Caballero, E; Espinosa, N; García, F; García-Álvarez, M; García-Bujalance, S; García-Fraile, LJ; Gómez-Sirvent, JL; Guerrero-Beltrán, C; Iborra, A; Imaz, A; Iribarren, JA; Martínez, M; Martínez-Sanz, J; Masiá, M; Montero, M; Moreno, S; Olalla, J; Peraire, J; Portilla, J; Rivero, M; Rodríguez, C; Vidal-Ampurdanes, MC1
DiBenedetto, A; Fackler, P; Fan, L; Iwamoto, M; Khalilieh, S; Stoch, SA; Triantafyllou, I; Vallee, MH; Yee, KL1
Alves Saldanha, S; André, P; Buclin, T; Cavassini, M; Choong, E; Courlet, P; Csajka, C; Decosterd, LA; Desfontaine, V; Günthard, HF; Marzolini, C1
Talwani, R; Temesgen, Z1
Cocklin, S; Karadsheh, R; Meuser, ME1
Barat, C; Drouin, J; Gagnon, MT; Leboeuf, M; Proust, A; Tremblay, MJ; Vanasse, F1
Kraft, WK; Lam, E; Schaefer, J; Zhan, T; Zheng, R1
Azeem, SM; Frey, KM; Muwonge, AN; Tabassum, T1
Calvi, RM; Chiarella, J; Deeks, SG; Ho, YC; Hoh, R; Jenike, KM; Yeh, YJ1
Fulco, PP; Herity, LB1
Hewlett, K; Hughes, SH; Pauly, GT; Schneider, JP; Smith, SJ1
Arduino, RC; Bauch, T; Chen, M; Graviss, EA; Kimata, JT; Li, M; Liu, W; Wang, J1
Iwamoto, M; Khalilieh, S; Sanchez, R; Stoch, SA; Wenning, L; Yee, KL1
Alam, SM; Anasti, K; Cronin, K; Desaire, H; Ding, H; Eaton, A; Go, EP; Haynes, BF; Kappes, J; Montefiori, D; Parks, R; Saunders, KO; Sodroski, J1
Kandala, B; Vaddady, P; Yee, KL1
Arribas, JR; Battegay, M; Béguelin, C; Bhagani, S; Cinque, P; Collins, S; Cotter, A; De Miguel, R; Guaraldi, G; Kirk, O; Kowalska, JD; Mallon, P; Marzolini, C; Molina, JM; Podlekareva, D; Rauch, A; Ryom, L; Winston, A1
Asante-Appiah, E; Feng, M; Graham, D; Hazuda, DJ; Hwang, C; Kumar, S; Lai, MT; Martin, EA; Ngo, W; Sklar, P1
Feng, LS; Liu, D; Zhao, F; Zheng, MJ1
Boccuto, A; Dragoni, F; Giammarino, F; Giannini, A; Hosseini, BA; Saladini, F; Shafer, RW; Vicenti, I; Zazzi, M1
Alvarez Bognar, F; Elion, R; Hwang, C; Martin, EA; Orkin, C; Rockstroh, JK; Sklar, P; Thompson, M; Xu, ZJ1
Abdel-Daim, MM; Afify, MA; Ahmed, IGG; Alkahtani, TA; Alrowili, ASM; Altulayhi, RI; Bin-Jumah, M; Ghozy, S1
Hanna, GJ; Hwang, C; Kumar, S; Lin, G; Martin, E; Molina, JM; Orkin, C; Sax, PE; Squires, KE; Sussmann, O; Teppler, H1
Chinen, M; Hayashida, T; Hirano, A; Kobayashi, M; Masuda, J; Watanabe, K1
Bassa, A; Hill, A; Kumar, S; Mngqibisa, R; Nelson, M; Orkin, C; Rassool, M; Rodgers, A; Teal, V; Teppler, H; Winston, A1
Bickel, M; Cahn, P; Greaves, W; Johnson, M; Kumar, P; Molina, JM; Morais, C; Rizzardini, G; Sklar, P; Wan, H; Xu, ZJ1
Brenner, BG; Ibanescu, RI; Oliveira, M; Routy, JP; Thomas, R1
Hans, L; Moorhouse, M; Steegen, K; Venter, WD; Wensing, AM1
Afani Saud, A; Bettacchi, C; Chahin Anania, C; Correll, T; DeJesus, E; Eves, K; Grandhi, A; Hanna, GJ; Hwang, C; Molina, JM; Olsen Klopfer, S; Robertson, MN; Sklar, P; Yazdanpanah, Y1
Ciccullo, A; D'Angelillo, A; Di Giambenedetto, S; Farinacci, D; Iannone, V; Lombardi, F; Tamburrini, E; Visconti, E1
Bieniasz, P1
Arenas-Pinto, A; Benn, P; Brima, N; Clarke, A; Copas, A; Fisher, M; Gilson, R; Hawkins, D; Milinkovic, A; Schembri, G; Williams, A1
Benko, E; Huibner, S; Kandel, G; Kaul, R; Kim, CJ; Kovacs, C; Ostrowski, M; Rousseau, R; Shahabi, K1
Abagyan, R; Cherezov, V; Han, GW; Handel, TM; Kufareva, I; Stevens, RC; Wu, B; Zheng, Y1
Alberto Arnaiz, J; Amin, J; Andrade-Villanueva, J; Belloso, W; Clark, A; Clarke, A; Cooper, D; Emery, S; Gatell, J; Gill, J; Harrigan, R; Horban, A; Kaiser, R; Kelleher, A; Losso, M; Madero, JS; Mallon, P; Pett, SL; Porteiro, N; Prazuck, T; Rockstroh, JK; Ruxrungtham, K; Silk, D; Sugiura, W; Tu, E; Wolff, M; Woolley, I1
Borm, K; Cashin, K; Churchill, M; Duncan, R; Ellenberg, P; Ellett, A; Flynn, JK; Gorry, PR; Gray, LR; Jubb, B; Lee, B; Lewin, SR; Lewis, M; Roche, M; Sterjovski, J; Westby, M; Zhou, J1
Amico, KR; Andrade, A; Andrew, P; Chege, W; Chen, YQ; Cottle, LM; Eshleman, SH; Frank, I; Gulick, RM; Hendrix, CW; Ho, K; Hodder, S; Klingman, KL; Landovitz, RJ; Manabe, YC; Marcus, C; Marzinke, MA; Mayer, KH; McCauley, M; McGowan, I; Richardson, P; Rinehart, AR; Rooney, JF; Salata, RA; Santana, J; Siegel, M; Stekler, JD; Swaminathan, S; Wilkin, TJ; Young, AM1
Belarbi, L; Chaix, ML; Dulioust, E; Duvivier, C; Ghosn, J; Launay, O; Lê, MP; Mahjoub, N; Peytavin, G; Salmon, D; Viard, JP1
Asmuth, DM; Chun, TW; Garcia, JC; Kashuba, AD; Landay, A; Ma, ZM; Mann, S; Miller, CJ; Pollard, RB; Sainz, T; Serrano-Villar, S; Thompson, CG; Troia-Cancio, P; Utay, NS1
Antinori, A; Canovari, B; Colafigli, M; Colangeli, V; D'Arminio Monforte, A; D'Avino, A; De Luca, A; Di Biagio, A; Di Giambenedetto, S; Fantauzzi, A; Francisci, D; Gagliardini, R; Ghisetti, V; Grima, P; Lamonica, S; Latini, A; Lisi, L; Mastroianni, C; Meini, G; Micheli, V; Navarra, P; Orofino, G; Re, MC; Rossetti, B; Rusconi, S; Sterrantino, G; Trezzi, M; Vignale, F; Vullo, V; Zazzi, M1
Abner, E; Chen, HC; Fanunza, E; Filion, GJ; Izquierdo-Bouldstridge, A; Jordan, A; Konuma, T; Mahmoudi, T; Stoszko, M; Zeng, L; Zhang, Q; Zhou, MM; Zorita, E1
Bruckman, RS; Campbell, GR; Durden, DL; Herns, SD; Joshi, S; Spector, SA1
Aralaguppe, SG; Ashokkumar, M; Hanna, LE; Neogi, U; Tripathy, SP1
Cahn, P; DeJesus, E; Hanna, GJ; Hwang, C; Kumar, S; Lai, MT; Lombaard, J; Lupinacci, L; Molina, JM; Nguyen, BY; Rodgers, A; Sax, PE; Sklar, P; Squires, K; Xu, X1
Chen, CH; Daelemans, D; De Clercq, E; Huang, B; Kang, D; Lee, KH; Liu, J; Liu, X; Liu, Z; Pannecouque, C; Tian, Y; Zhan, P; Zhang, H1
Anderson, JL; Harty, L; Jacobson, J; Khoury, G; Lee, MY; Lewin, SR; Li, S; Mota, TM; Purcell, DFJ; Tumpach, C1
Colombier, MA; Molina, JM1
Álvarez, H; Llibre, JM; Yzusqui, M1
Deeks, ED1
Cary, DC; Peterlin, BM1
Calvez, V; Ceccherini-Silberstein, F; Charpentier, C; Descamps, D; Di Carlo, D; Gennari, W; Marcelin, AG; Paraskevis, D; Perno, CF; Santoro, MM; Soulie, C; Sterrantino, G; Storto, A; Zazzi, M1
Claussen, A; de Greef, R; Ouerdani, A; Wenning, L; Yee, KL1
Andreoni, M; Antinori, A; Bagnarelli, P; Borghi, V; Bruzzone, B; Callegaro, AP; De Gennaro, M; Gianotti, N; Maffongelli, G; Maggiolo, F; Saladini, F; Sterrantino, G; Vergori, A; Zaccarelli, M; Zazzi, M1
Bouhajib, M; Fan, L; Iwamoto, M; Khalilieh, S; Sanchez, RI; Searle, S; Vaynshteyn, K; Yee, KL1
Cahn, P; Hanna, G; Hwang, C; Kumar, S; Martin, E; Molina, JM; Orkin, C; Rodgers, A; Sax, P; Squires, K; Teppler, H; Thompson, M; Xu, X1
DeJesus, E; Hanna, G; Hwang, C; Kumar, S; Lombaard, J; Martin, E; Molina, JM; Orkin, C; Rodgers, A1
Bordin-Wosk, T; Chun, V; Dhamija, A; Kadakia, A; Lin, AY1
Alamer, E; Ananworanich, J; Chen, H; Endsley, J; Fan, X; Gelman, BB; Hu, H; Kim, JH; Liu, Z; Michael, NL; Niu, Q; Robb, ML; Tian, B; Zhou, J1
Arastéh, K; Dretler, R; Frobose, C; Gatell, JM; Hagins, DP; Harvey, C; Hoffmann, C; Hwang, C; Kumar, S; Morales-Ramirez, JO; Osiyemi, O; Plettenberg, A; Portilla, J; Raffi, F; Rodgers, A; Rugina, S; Smith, DE; Teppler, H; Thompson, M; Wan, H; Xu, X1
Boyle, A; Khoo, S; Marzolini, C; Moss, CE1
Chapman, D; Demarest, J; Dong, WW; Ellery, S; Harrigan, PR; Heera, J; Mo, T; Poon, AF; Swenson, LC; Valdez, H1
Abi-Habib, S; Abrol, R; Berro, R; Goddard, WA; Grunbeck, A; Klasse, PJ; Lascano, D; Moore, JP; Sakmar, TP; Trzaskowski, B; Yasmeen, A1
Abrams, CF; Bewley, CA; Chaiken, IM; Emileh, A; Lalonde, JM; Moreira, DR; Tuzer, F; Umashankara, M; Yeh, H1
Archer, J; Arts, EJ; Gibson, RM; Henry, K; King, K; Olivo, PD; Poveda, E; Quiñones-Mateu, ME; Rhea, AM; Robertson, DL; Rose, JD; Soriano, V; Vazquez, AC; Weber, J; Winner, D; Wright, A; Wylie, D1
Bonora, S; Calcagno, A; Chiappetta, S; D'Avolio, A; Di Perri, G; Galli, A; Gonzalez de Requena, D; Lazzarin, A; Nozza, S; Simiele, M1
Arts, EJ; Dudley, DM; Lobritz, MA; Marozsan, AJ; Ratcliff, AN; Tilton, JC1
Bonora, S; Calcagno, A; D'Avolio, A; Di Perri, G; Ghisetti, V; Marinaro, L; Montrucchio, C; Trentini, L1
Adeyemi, O; Clagett, B; Dahl, V; Deeks, SG; Funderburg, NT; Gilman, LE; Hayes, TL; Hunt, PW; Landay, AL; Lederman, MM; Martin, JN; McLaughlin, B; Palmer, S; Rodriguez, B; Schacker, TW; Shacklett, BL; Shulman, NS; Somsouk, M1
Emery, S; Harrigan, R; Kaiser, R; Kaye, S; Kelleher, AD; Land, S; Marks, K; Pett, S; Schuelter, E; Swenson, LC; Tu, E1
Bon, I; Borderi, M; Calza, L; Clò, A; Colangeli, V; Cricca, M; Gibellini, D; Miserocchi, A; Morini, S; Re, MC1
Chikere, K; Churchill, MJ; Duncan, R; Ellett, A; Flynn, JK; Gorry, PR; Gray, LR; Jubb, B; Lee, B; Lewin, SR; Moore, MS; Payne, RJ; Ramsland, PA; Roche, M; Salimi, H; Sterjovski, J; Webb, NE; Westby, M; Wilkinson, BL; Zappi, H1
Hanna, GJ; Healy, MD; Hwang, C; Krystal, M; Lataillade, M; Ray, N; Whitcomb, J; Wind-Rotolo, M1
Khamadi, SA; Muigai, AW; Ng'ang'a, Z; Nyamache, AK1
Aoki, R; Blauvelt, A; Gatanaga, H; Kawamura, T; Koyanagi, Y; Matsuzawa, T; Moriishi, K; Ogawa, Y; Shimada, S; Takahashi, M1
Dong, W; Harrigan, PR; Hoepelman, AI; McGovern, RA; Nijhuis, M; Poon, AF; Symons, J; van Ham, PM; van Lelyveld, SF; Wensing, AM1
Bicudo, EL; Cassoli, LM; da Eira, M; de Andrade Neto, JL; Furtado, J; Leite, OH; Lewi, DS; Lima, MP; Lopes, MI; Machado, AA; Madruga, JV; Miranda, AF; Netto, EM; Pedro, Rde J; Portsmouth, S; Santini-Oliveira, M; Santos, BR; Tupinambas, U; Wajsbrot, DB1
Cai, YD; Chen, L; Huang, T; Jiang, M; Kong, XY; Li, BQ; Lu, J; Niu, B; Wei, ZJ; Zheng, MY1
Cazabat, M; Coassin, L; Delobel, P; Izopet, J; Loiseau, C; Marchou, B; Massip, P; Raymond, S; Requena, M; Saliou, A1
Acosta, EP; Adeyemi, O; Berzins, B; Castro, J; Eron, JJ; Kuritzkes, DR; Lalezari, J; Lu, D; Ryscavage, P; Swindells, S; Taiwo, B; Tsibris, A1
Guo, H; Kong, X; Liu, B; Liu, C; Wood, C1
Feucht, N; Hadeler, J; Lanzl, I; Loos, D; Schmid, RM; Schwerdtfeger, C; Spinner, CD1
Bumpus, NN; Hendrix, CW; To, EE1
Bellazzi, LI; Bianco, C; Bruzzone, B; Colao, G; Corsi, P; De Luca, A; Monno, L; Pagano, G; Paolucci, S; Punzi, G; Rossetti, B; Setti, M; Zazzi, M1
Degli Antoni, A; Ferrari, C; Fragola, V; Manfredi, R; Weimer, LE1
Autran, B; Barbuat, C; Corbeau, P; Cuzin, L; Flandre, P; Ghosn, J; Lascoux-Combe, C; Lavigne, JP; Psomas, C; Reynes, J; Trabelsi, S1
Deeks, SG; Hunt, PW; Lederman, MM1
Brumme, CJ; Chan, D; Chapman, D; Chui, CK; Demarest, JF; Dong, W; Goodrich, J; Harrigan, PR; Heera, J; James, I; Lewis, M; Mo, T; Portsmouth, S; Swenson, LC; Valdez, H; Woods, CK1
Eggers, B; Fan, L; Fang, H; Hanna, GJ; Healy, M; Hwang, C; Krystal, M; Langley, DR; Lataillade, M; McAuliffe, B; Nowicka-Sans, B; Ray, N; Zhou, N1
Gianella, S; Jordan, PS; Karris, MY; Little, SJ; Massanella, M; Patel, D; Pérez-Santiago, J; Richman, DD; Smith, DM; Spina, CA; Var, SR; Young, JA1
Ballestero, M; Blanco, J; Boix, J; Buzon, MJ; Clotet, B; Esteve, A; Gatell, JM; Llibre, JM; Manzardo, C; Martinez-Picado, J; Massanella, M; Miró, JM; Ouchi, D; Puertas, MC1
Banerjea, AC; Gupta, S; Neogi, U; Shet, A; Srinivasa, H1
Alcami, J; Pérez-Olmeda, M1
Piguet, V1
Abeli, C; Adorni, F; Bai, F; Bonora, S; Buonomini, AR; Butini, L; Capetti, A; Colafigli, M; Colella, E; D'Annunzio, M; d'Ettorre, G; Di Biagio, A; Di Nardo Stuppino, S; Di Pietro, M; Focà, E; Francisci, D; Marchetti, G; Meraviglia, P; Merlini, E; Montano, M; Morosi, M; Mosti, S; Orofino, G; Parruti, G; Rusconi, S; Soria, A; Tau, P; Tommasi, C; Vitiello, P1
Asante-Appiah, E; Burch, J; Campeau, LC; Cauchon, E; Côté, B; DiStefano, D; Ducharme, Y; Falgueyret, JP; Feng, M; Grobler, J; Hazuda, DJ; Lai, MT; Li, Y; Lu, M; Miller, MD; Sachs, N; Tawa, P; Witmer, M; Yan, Y1
Abad-Fernández, M; Díaz, L; Dronda, F; Gutiérrez, C; Hernández-Novoa, B; Madrid, N; Moreno, A; Moreno, S; Muñoz-Fernández, MA; Serrano-Villar, S; Vallejo, A; Zamora, J1
Burnside, R; Fatkenheuer, G; Goodrich, J; Gulick, RM; Hardy, WD; Heera, JR; Mukwaya, G; Nelson, MR; Portsmouth, S1
Kravchenko, AV1
Caskey, M; Evering, TH; Garmon, D; La Mar, M; Markowitz, M; Mohri, H; Palmer, S; Prada, N; Rodriguez, K; Sahi, V1
Bigoloni, A; Bonora, S; Calcagno, A; Carbone, A; Castagna, A; D'Avolio, A; Galli, L; Lazzarin, A; Nozza, S; Pignataro, AR; Ripa, M1
Blanco, J; Brander, C; Bravo, I; Clotet, B; Escrig, R; Gatell, JM; Iwamoto, A; Kawana-Tachikawa, A; Llibre, JM; Manzardo, C; Martinez-Picado, J; Miro, JM; Mothe, B; Pozniak, AL; Puertas, MC; Puig, J1
Bozzano, F; Cenderello, G; De Maria, A; Dentone, C; Di Biagio, A; Fenoglio, D; Filaci, G; Fraccaro, P; Mantia, E; Orofino, G; Parodi, A; Signori, A1
Mitra, AK; Pal, D; Patel, M; Paturi, DK; Vadlapatla, RK1
Assoumou, L; Chablais, L; Costagliola, D; Duvivier, C; Katlama, C; Kolta, S; Marcelin, AG; Mercié, P; Peytavin, G; Pialoux, G; Simon, A; Soulié, C; Valantin, MA1
Audino, A; Baietto, L; Bonora, S; D'Avolio, A; Di Perri, G; Sciandra, M; Simiele, M1
Bancalero, P; Chueca, N; García, C; Jiménez, P; Macías, J; Márquez, M; Merino, D; Muñoz, L; Ojeda, G; Pasquau, J; Pineda, JA; Recio, E1
Evans, A; Forbes, CJ; Malcolm, RK; McCoy, CF; Moore, JP; Murphy, DJ; Shattock, RJ; Woolfson, AD1
Casado, JL; Dronda, F; Estébanez, M; González, J; Hernández-Novoa, B; Madrid-Elena, N; Moreno, A; Moreno, S; Pérez-Elias, MJ; Pérez-Molina, JA; Zamora, J1
McGowan, I1
Panos, G; Watson, DC1
Leal, M; Martínez-Bonet, M; Méndez-Lagares, G; Muñoz-Fernández, MA; Pacheco, YM; Pozo-Balado, MM; Rodríguez-Méndez, MM; Rosado, I; Ruiz-Mateos, E; Vidal, F1
Bullen, CK; Durand, CM; Laird, GM; Siliciano, JD; Siliciano, RF1
Siegel, MO1
Baldelli, F; Baroncelli, S; Cecchini, E; Falcinelli, E; Floridia, M; Francisci, D; Gresele, P; Petito, E; Weimer, LE1
Beliakova-Bethell, N; Dubé, MP; Goicoechea, M; Haubrich, R; Jain, S; Lada, SM; Rought, SE; Spina, CA; Sun, X; Witt, MD; Woelk, CH1
Caballero, E; Cabezas, T; De Mendoza, C; Eiros, JM; Lopez, M; Parra, P; Poveda, E; Roc, L; Rodríguez, C; Soriano, V; Treviño, A1
Bonora, S; Calcagno, A; Chiappetta, S; D'Avolio, A; Di Perri, G; Ghisetti, V; Lazzarin, A; Milia, MG; Nozza, S; Simiele, M1
Bigoloni, A; Carbone, A; Castagna, A; Chiappetta, S; Galli, L; Gianotti, N; Lazzarin, A; Nozza, S; Ripa, M; Spagnuolo, V; Tambussi, G1
Ajassa, C; Ermocida, A; Lichtner, M; Mastroianni, CM; Mengoni, F; Rossi, R; Sauzullo, I; Vullo, V1
Colby-Germinario, SP; Kramer, VG; Mesplède, T; Oliviera, M; Varsaneux, O; Wainberg, MA1
Ball, C; Woodrow, KA1
Back, D; Boffito, M; Else, L; Gazzard, B; Jackson, A; Nelson, M; Newell, S; Rockwood, N; Waters, L1
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Abel, S; Muirhead, GJ; Ridgway, CE; Russell, D; Taylor-Worth, RJ1
Abel, S; Jenkins, TM; Muirhead, GJ; Ridgway, CE; Whitlock, LA1
Boffito, M; Muirhead, GJ; Pozniak, AL; Ridgway, CE; Russell, D1
Chan, PL; McFadyen, L; Weatherley, B1
Abel, S; Dorr, P; Jacqmin, P; James, I; Jenkins, TM; Rosario, MC; van der Ryst, E1
Jacqmin, P; McFadyen, L; Wade, JR1
Taéron, C1
Brunel, AS; Fraisse, T; Lechiche, C; Mauboussin, JM; Pinzani, V; Sotto, A1
de la Tribonnière, X; Reynes, J; Yazdanpanah, Y1
Peytavin, G1
Chidiac, C; Katlama, C; Yeni, P1
al-Haidary, AD; Catanzaro, A; Cloud, GA; Graybill, JR; Hostetler, JS; Larsen, RA; Rinaldi, MG; Sharkey, PK; Stevens, DA; Tucker, RM1
Chiritescu, ME; Chiritescu, MM; Scher, RK1
Ruhnke, M; Schmidt-Westhausen, A; Trautmann, M1
Cantu, RA; Fothergill, AW; Kirkpatrick, WR; Lopez-Ribot, JL; Mcatee, RK; McCarthy, DI; Patterson, TF; Revankar, SG; Rinaldi, MG; Sanche, SE1
Krcmery, V1
Müller, FM; Weig, M1
Arzeni, D; Barchiesi, F; D'Angelo, M; Falconi Di Francesco, L; Giuliana, G; Milici, ME; Pizzo, G; Scalise, G1
Fothergill, AW; Gonzalez, G; Perea, S; Rinaldi, MG; Sutton, DA1
Graybill, JR; Hardin, TC; Lam, YF; Rinaldi, MG; Sharkey, PK; Wallace, JE1

Reviews

89 review(s) available for triazoles and HIV Infections

ArticleYear
Doravirine: its role in HIV treatment.
    Current opinion in HIV and AIDS, 2022, 01-01, Volume: 17, Issue:1

    Topics: Anti-HIV Agents; HIV Infections; Humans; Pyridones; Reverse Transcriptase Inhibitors; Triazoles

2022
Peptide Triazole Inhibitors of HIV-1: Hijackers of Env Metastability.
    Current protein & peptide science, 2023, Volume: 24, Issue:1

    Topics: Binding Sites; HIV Infections; HIV-1; Humans; Peptides; Sulfhydryl Compounds; Triazoles

2023
Doravirine: A Return of the NNRTI Class?
    The Annals of pharmacotherapy, 2020, Volume: 54, Issue:1

    Topics: Anti-HIV Agents; HIV Infections; HIV-1; Humans; Pyridones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Treatment Outcome; Triazoles

2020
Islatravir for the treatment and prevention of infection with the human immunodeficiency virus type 1.
    Current opinion in HIV and AIDS, 2020, Volume: 15, Issue:1

    Topics: Animals; Anti-HIV Agents; Deoxyadenosines; Drug Combinations; Drug Evaluation, Preclinical; HIV Infections; HIV-1; Humans; Lamivudine; Macaca mulatta; Pre-Exposure Prophylaxis; Pyridones; Reverse Transcriptase Inhibitors; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Triazoles; Viral Load

2020
Doravirine: a new non-nucleoside reverse transcriptase inhibitor for the treatment of HIV infection.
    Drugs of today (Barcelona, Spain : 1998), 2020, Volume: 56, Issue:2

    Topics: Anti-HIV Agents; Cytochrome P-450 CYP3A; HIV Infections; HIV-1; Humans; Japan; Pyridones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Triazoles

2020
Clinical Pharmacokinetics of the Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor Doravirine: An Assessment of the Effect of Patient Characteristics and Drug-Drug Interactions.
    Clinical drug investigation, 2020, Volume: 40, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Area Under Curve; Drug Interactions; Female; Food-Drug Interactions; HIV Infections; HIV-1; Humans; Male; Middle Aged; Pyridones; Reverse Transcriptase Inhibitors; Triazoles; Young Adult

2020
Review of Doravirine Resistance Patterns Identified in Participants During Clinical Development.
    Journal of acquired immune deficiency syndromes (1999), 2020, 12-15, Volume: 85, Issue:5

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclopropanes; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; In Vitro Techniques; Pyridones; Rilpivirine; Triazoles

2020
1,2,3-Triazole hybrids with anti-HIV-1 activity.
    Archiv der Pharmazie, 2021, Volume: 354, Issue:1

    Topics: Anti-HIV Agents; HIV Infections; Humans; Structure-Activity Relationship; Triazoles

2021
Efficacy and safety of doravirine in treatment-naive HIV-1-infected adults: a systematic review and meta-analysis.
    Environmental science and pollution research international, 2021, Volume: 28, Issue:9

    Topics: Adult; Anti-HIV Agents; HIV Infections; HIV-1; Humans; Pyridones; Triazoles

2021
Doravirine: a review.
    Current opinion in HIV and AIDS, 2018, Volume: 13, Issue:4

    Topics: Anti-HIV Agents; HIV Infections; Humans; Pyridones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Triazoles

2018
Clinical Impact of Virological Failure and Resistance Analysis Definitions used in Pivotal Clinical Trials of Initial Antiretroviral Treatment: A Systematic Review
    AIDS reviews, 2018, Volume: 20, Issue:3

    Topics: Amides; Anti-Retroviral Agents; Clinical Trials as Topic; Cobicistat; Darunavir; Drug Resistance, Viral; Genotype; Heterocyclic Compounds, 3-Ring; Heterocyclic Compounds, 4 or More Rings; HIV Infections; Humans; Oxazines; Piperazines; Pyridones; Quinolones; Rilpivirine; RNA, Viral; Triazoles; Viral Load

2018
Doravirine: First Global Approval.
    Drugs, 2018, Volume: 78, Issue:15

    Topics: Anti-HIV Agents; Drug Approval; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Pyridones; Reverse Transcriptase Inhibitors; Tablets; Tenofovir; Triazoles

2018
Clinical Pharmacodynamics, Pharmacokinetics, and Drug Interaction Profile of Doravirine.
    Clinical pharmacokinetics, 2019, Volume: 58, Issue:12

    Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Interactions; HIV Infections; HIV-1; Humans; Pyridones; Reverse Transcriptase Inhibitors; Triazoles

2019
Determination of HIV tropism and its use in the clinical practice.
    Expert review of anti-infective therapy, 2013, Volume: 11, Issue:12

    Topics: Biological Assay; Cyclohexanes; Genotype; HIV Fusion Inhibitors; HIV Infections; HIV-1; Host-Pathogen Interactions; Humans; Maraviroc; Molecular Typing; Phenotype; Receptors, CCR5; Receptors, CXCR4; Sensitivity and Specificity; Triazoles; Viral Tropism

2013
[Use of maraviroc, the first CCR5 receptor antagonist, in HIV treatment regimens].
    Terapevticheskii arkhiv, 2013, Volume: 85, Issue:11

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; HIV; HIV Infections; Humans; Maraviroc; Treatment Outcome; Triazoles

2013
Clinically relevant drug-drug interactions between antiretrovirals and antifungals.
    Expert opinion on drug metabolism & toxicology, 2014, Volume: 10, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Alkynes; Anti-Retroviral Agents; Antifungal Agents; Benzoxazines; Carbamates; Cyclopropanes; Drug Interactions; Drug Monitoring; Echinocandins; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Itraconazole; Mycoses; Organophosphates; Pyrimidines; Ritonavir; Sulfonamides; Triazoles; Voriconazole

2014
An overview of antiretroviral pre-exposure prophylaxis of HIV infection.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2014, Volume: 71, Issue:6

    Topics: Adenine; Anti-HIV Agents; Cyclohexanes; Drug Resistance, Viral; Female; HIV Infections; Humans; Male; Maraviroc; Medication Adherence; Nitriles; Organophosphonates; Pre-Exposure Prophylaxis; Pyridones; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir; Triazoles

2014
Effect of HIV-1 subtype and tropism on treatment with chemokine coreceptor entry inhibitors; overview of viral entry inhibition.
    Critical reviews in microbiology, 2015, Volume: 41, Issue:4

    Topics: CCR5 Receptor Antagonists; CD4 Antigens; Cyclohexanes; Disease Progression; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Receptors, CCR5; Receptors, CXCR4; Triazoles; Viral Tropism; Virus Internalization

2015
Targeting CCR5 for anti-HIV research.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2014, Volume: 33, Issue:11

    Topics: Anti-HIV Agents; Biological Therapy; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; Drug Discovery; HIV Infections; Humans; Maraviroc; Receptors, CCR5; Triazoles

2014
Pharmacological intervention at CCR1 and CCR5 as an approach for cancer: help or hindrance.
    Current topics in medicinal chemistry, 2014, Volume: 14, Issue:13

    Topics: Animals; Antineoplastic Agents; Cyclohexanes; HIV Infections; Humans; Maraviroc; Molecular Structure; Neoplasms; Receptors, CCR1; Receptors, CCR5; Triazoles

2014
Chemokine receptor CCR5 antagonist maraviroc: medicinal chemistry and clinical applications.
    Current topics in medicinal chemistry, 2014, Volume: 14, Issue:13

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Drug Discovery; HIV; HIV Infections; Humans; Maraviroc; Receptors, CCR5; Structure-Activity Relationship; Triazoles; Virus Replication

2014
HIV-1 gp120 as a therapeutic target: navigating a moving labyrinth.
    Expert opinion on therapeutic targets, 2015, Volume: 19, Issue:6

    Topics: Animals; Anti-HIV Agents; Cyclohexanes; Drug Design; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Maraviroc; Molecular Targeted Therapy; Receptors, CCR5; Triazoles

2015
Immune reconstitution inflammatory syndrome in a patient with progressive multifocal leukoencephalopathy.
    BMJ case reports, 2015, Jun-10, Volume: 2015

    Topics: CCR5 Receptor Antagonists; CD8-Positive T-Lymphocytes; Cyclohexanes; Disease Progression; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Maraviroc; Middle Aged; Treatment Outcome; Triazoles

2015
Maraviroc: a review of its use in HIV infection and beyond.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Interactions; Drug Resistance, Viral; Genotype; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Mutation; Phenotype; Polypharmacy; Treatment Outcome; Triazoles

2015
Off-label use of maraviroc in clinical practice.
    Expert review of anti-infective therapy, 2016, Volume: 14, Issue:1

    Topics: Animals; Arthritis, Rheumatoid; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; Graft vs Host Disease; Hematologic Neoplasms; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Mice; Off-Label Use; Sarcoidosis; Triazoles

2016
[Companion Diagnostics for Selecting Antiretroviral Drugs against HIV-1].
    Rinsho byori. The Japanese journal of clinical pathology, 2015, Volume: 63, Issue:11

    Topics: Alleles; Anti-Retroviral Agents; CCR5 Receptor Antagonists; Cyclohexanes; Dideoxynucleosides; HIV Infections; HIV-1; HLA-B Antigens; Humans; Maraviroc; Pharmacogenetics; Precision Medicine; Reverse Transcriptase Inhibitors; Triazoles; Viral Tropism

2015
Efficacy and safety of contemporary dual-drug antiretroviral regimens as first-line treatment or as a simplification strategy: a systematic review and meta-analysis.
    The lancet. HIV, 2016, Volume: 3, Issue:8

    Topics: Anti-HIV Agents; Cyclohexanes; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Male; Maraviroc; Middle Aged; Odds Ratio; Reverse Transcriptase Inhibitors; Risk; Triazoles; Viral Load

2016
CCR5 receptor antagonists in preclinical to phase II clinical development for treatment of HIV.
    Expert opinion on investigational drugs, 2016, Volume: 25, Issue:12

    Topics: Animals; Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Design; HIV Infections; Humans; Imidazoles; Maraviroc; Sulfoxides; Triazoles

2016
Reviews of anti-infective agents: maraviroc: the first of a new class of antiretroviral agents.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Jul-15, Volume: 47, Issue:2

    Topics: Anti-HIV Agents; Biological Assay; CCR5 Receptor Antagonists; CD4-Positive T-Lymphocytes; Clinical Trials as Topic; Cyclohexanes; Cytochrome P-450 CYP3A; Drug Interactions; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Maraviroc; Receptors, CCR5; Triazoles; Tropism; Virus Internalization

2008
New treatment options for HIV salvage patients: an overview of second generation PIs, NNRTIs, integrase inhibitors and CCR5 antagonists.
    The Journal of infection, 2008, Volume: 57, Issue:1

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; Darunavir; HIV Fusion Inhibitors; HIV Infections; HIV Integrase Inhibitors; HIV Protease Inhibitors; HIV-1; Humans; Maraviroc; Nitriles; Pyridazines; Pyridines; Pyrimidines; Pyrones; Pyrrolidinones; Raltegravir Potassium; Reverse Transcriptase Inhibitors; Salvage Therapy; Sulfonamides; Treatment Outcome; Triazoles

2008
Maraviroc: a CCR5-receptor antagonist for the treatment of HIV-1 infection.
    Clinical therapeutics, 2008, Volume: 30, Issue:7

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Interactions; Drug Resistance, Multiple, Viral; HIV Infections; HIV-1; Humans; Maraviroc; Triazoles

2008
Maraviroc, risks and benefits: a review of the clinical literature.
    Expert opinion on drug safety, 2008, Volume: 7, Issue:5

    Topics: CCR5 Receptor Antagonists; Clinical Trials, Phase III as Topic; Cyclohexanes; Drug Resistance, Multiple, Viral; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Triazoles

2008
Optimal use of maraviroc in clinical practice.
    AIDS (London, England), 2008, Nov-12, Volume: 22, Issue:17

    Topics: Antiretroviral Therapy, Highly Active; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Drug Interactions; Drug Resistance, Viral; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Receptors, CCR5; Triazoles; Tropism; Viral Load

2008
Developing clinical role of a CCR5 co-receptor antagonist in HIV-1 infection.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:18

    Topics: Anti-Retroviral Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Therapy, Combination; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles; Virus Replication

2008
Inhibitors of viral entry.
    Handbook of experimental pharmacology, 2009, Issue:189

    Topics: Animals; Chemokines; Cyclohexanes; Drug Resistance, Viral; Enfuvirtide; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Peptide Fragments; Triazoles; Virus Attachment; Virus Internalization

2009
[Viral entry as therapeutic target. Current situation of entry inhibitors].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 11

    Topics: Adult; Amides; Benzoates; CCR5 Receptor Antagonists; CD4 Antigens; Chemokines, CC; Chemokines, CXC; Clinical Trials as Topic; Cyclohexanes; Diketopiperazines; Drug Design; env Gene Products, Human Immunodeficiency Virus; HIV; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Membrane Fusion; Models, Molecular; Piperazines; Pyrimidines; Quaternary Ammonium Compounds; Receptors, CCR5; Receptors, CXCR4; Spiro Compounds; Structure-Activity Relationship; Triazoles; Virus Attachment; Virus Internalization

2008
[Pharmacokinetics, interactions and mechanism of action of maraviroc].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 11

    Topics: Adolescent; Adult; Aged; Biological Availability; Biotransformation; CCR5 Receptor Antagonists; Chemokines, CC; Clinical Trials as Topic; Cyclohexanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Design; Drug Interactions; env Gene Products, Human Immunodeficiency Virus; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Kidney Diseases; Liver Diseases; Maraviroc; Membrane Fusion; Receptors, CCR5; Triazoles; Virus Attachment; Virus Internalization; Virus Replication

2008
[Maraviroc efficacy in clinical studies on the development of the molecule].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 11

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Clinical Trials, Phase IV as Topic; Cyclohexanes; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Design; Drug Resistance, Multiple, Viral; env Gene Products, Human Immunodeficiency Virus; HIV; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Multicenter Studies as Topic; Salvage Therapy; Treatment Outcome; Triazoles

2008
[Secondary effects of treatment with maraviroc and other CCR5 antagonists. Potential impact of the CCR5 blocker].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 11

    Topics: Adult; Benzoates; CCR5 Receptor Antagonists; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Comorbidity; Cyclohexanes; Diketopiperazines; Disease Susceptibility; Drug Design; env Gene Products, Human Immunodeficiency Virus; HIV Fusion Inhibitors; HIV Infections; Homozygote; Humans; Hyperlipidemias; Incidence; Infections; Maraviroc; Membrane Fusion; Neoplasms; Piperazines; Receptors, CCR5; Sequence Deletion; Spiro Compounds; Triazoles; Virus Attachment; Virus Internalization

2008
[Mechanisms of resistance and failure of treatment with maraviroc].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 11

    Topics: Amino Acid Sequence; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance, Viral; env Gene Products, Human Immunodeficiency Virus; Genes, env; HIV; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Membrane Fusion; Molecular Sequence Data; Multicenter Studies as Topic; Peptide Fragments; Receptors, CXCR4; Selection, Genetic; Treatment Failure; Triazoles; Virus Attachment; Virus Internalization

2008
[At what time and with which combinations should maraviroc be indicated in the new antiretroviral treatment scenario?].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 11

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Anti-Infective Agents; Antiretroviral Therapy, Highly Active; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; HIV; HIV Infections; Humans; Maraviroc; Membrane Fusion; Receptors, CXCR4; Salvage Therapy; Triazoles; Viral Load; Virus Attachment

2008
[Conclusions and perspectives. Maraviroc].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 11

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; Drug Design; Drug Resistance, Viral; Drug Therapy, Combination; Gene Products, env; HIV; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Membrane Fusion; Peptide Fragments; Receptors, CXCR4; Salvage Therapy; Selection, Genetic; Triazoles; Virus Attachment; Virus Internalization

2008
Maraviroc, a CCR5 coreceptor antagonist that blocks entry of human immunodeficiency virus type 1.
    Pharmacotherapy, 2009, Volume: 29, Issue:3

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; HIV Infections; HIV-1; Humans; Maraviroc; Receptors, CCR5; Receptors, CXCR4; Triazoles; Virus Internalization

2009
Maraviroc: a coreceptor CCR5 antagonist for management of HIV infection.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2009, Apr-15, Volume: 66, Issue:8

    Topics: Animals; CCR5 Receptor Antagonists; Cyclohexanes; Disease Management; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Receptors, CCR5; Triazoles

2009
Immunotherapies in HIV-1 infection.
    Current opinion in HIV and AIDS, 2009, Volume: 4, Issue:3

    Topics: Cyclohexanes; HIV Infections; HIV-1; Humans; Immunologic Factors; Immunotherapy; Interleukin-2; Maraviroc; Treatment Outcome; Triazoles

2009
[Role of the new molecules in antiretroviral therapy. Position of raltegravir].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 12

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; Darunavir; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Enfuvirtide; Forecasting; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV Integrase Inhibitors; Humans; Maraviroc; Nitriles; Peptide Fragments; Pyridazines; Pyridines; Pyrimidines; Pyrones; Pyrrolidinones; Raltegravir Potassium; Reverse Transcriptase Inhibitors; Sulfonamides; Triazoles

2008
Maraviroc: a new CCR5 antagonist.
    Expert review of anti-infective therapy, 2009, Volume: 7, Issue:1

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Child; Clinical Trials as Topic; Cyclohexanes; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Pregnancy; Treatment Outcome; Triazoles

2009
Entry inhibitors in the treatment of HIV-1 infection.
    Antiviral research, 2010, Volume: 85, Issue:1

    Topics: Cyclohexanes; Drug Resistance, Viral; Enfuvirtide; History, 20th Century; History, 21st Century; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Peptide Fragments; Triazoles

2010
Maraviroc: pharmacokinetics and drug interactions.
    Antiviral therapy, 2009, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Anti-Infective Agents; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Reverse Transcriptase Inhibitors; Triazoles; Young Adult

2009
When and how to use maraviroc in HIV-infected patients.
    AIDS (London, England), 2009, Nov-27, Volume: 23, Issue:18

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Drug Resistance, Viral; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Triazoles; Viral Tropism

2009
Novel drug classes: entry inhibitors [enfuvirtide, chemokine (C-C motif) receptor 5 antagonists].
    Current opinion in HIV and AIDS, 2009, Volume: 4, Issue:6

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Enfuvirtide; HIV; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Peptide Fragments; Piperazines; Pyrimidines; Salvage Therapy; Triazoles; Virus Internalization

2009
Novel CCR5 antagonists for the treatment of HIV infection: a review of compounds patented in 2006 - 2008.
    Expert opinion on therapeutic patents, 2010, Volume: 20, Issue:3

    Topics: AIDS Vaccines; Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Delivery Systems; Drug Resistance, Viral; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Patents as Topic; Triazoles

2010
Treatment of HIV infection with the CCR5 antagonist maraviroc.
    Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:7

    Topics: CCR5 Receptor Antagonists; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclohexanes; Drug Resistance, Viral; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Triazoles; Viral Tropism

2010
[CCR5-antagonists: contribution of a new antiretroviral class to the management of HIV infection].
    Medecine et maladies infectieuses, 2010, Volume: 40, Issue:5

    Topics: Anti-Retroviral Agents; CCR5 Receptor Antagonists; Cyclohexanes; HIV; HIV Infections; Humans; Maraviroc; Triazoles; Viral Tropism

2010
Maraviroc: a review of its use in the management of CCR5-tropic HIV-1 infection.
    Drugs, 2010, Jun-18, Volume: 70, Issue:9

    Topics: Adolescent; Adult; Antiretroviral Therapy, Highly Active; CCR5 Receptor Antagonists; Cyclohexanes; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Randomized Controlled Trials as Topic; Receptors, CCR5; Treatment Failure; Treatment Outcome; Triazoles; Viral Load; Viral Tropism; Young Adult

2010
[Pharmacological profile and clinical findings of Maraviroc (Celsentri® Tablets)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2010, Volume: 136, Issue:6

    Topics: Animals; Anti-HIV Agents; CCR5 Receptor Antagonists; CD4 Antigens; Clinical Trials as Topic; Cyclohexanes; Drug Resistance, Viral; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Maraviroc; Protein Binding; Tablets; Triazoles

2010
Maraviroc first-line therapy for HIV infection. Too risky.
    Prescrire international, 2010, Volume: 19, Issue:110

    Topics: Antiretroviral Therapy, Highly Active; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Risk Factors; Triazoles

2010
Clinical use of CCR5 inhibitors in HIV and beyond.
    Journal of translational medicine, 2011, Jan-27, Volume: 9 Suppl 1

    Topics: Animals; Antiviral Agents; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; Disease Models, Animal; Encephalitis, Tick-Borne; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Protein Binding; Triazoles; West Nile Fever

2011
Update on microbicide research and development - seeking new HIV prevention tools for women.
    European journal of medical research, 2011, Jan-27, Volume: 16, Issue:1

    Topics: Adenine; Administration, Intravaginal; Adult; Africa South of the Sahara; Anti-HIV Agents; Anti-Infective Agents; Clinical Trials as Topic; Cyclohexanes; Drug Discovery; Female; HIV Infections; Humans; Male; Maraviroc; Organophosphonates; Pyridines; Pyrimidines; Tenofovir; Triazoles; Urea

2011
HIV entry inhibitors: progress in development and application.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:2

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; CD4 Antigens; Cyclohexanes; Drug Resistance, Viral; Enfuvirtide; HIV Envelope Protein gp120; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Molecular Structure; Peptide Fragments; Receptors, CCR5; Receptors, Chemokine; Receptors, CXCR4; Triazoles

2010
[The newest developments in anti-HIV-1 drugs].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:2

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cyclohexanes; Drug Resistance, Viral; Enfuvirtide; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV Integrase Inhibitors; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Maraviroc; Molecular Structure; Peptide Fragments; Pyrrolidinones; Raltegravir Potassium; Saquinavir; Triazoles; Virus Replication; Zidovudine

2010
Clinical utility of maraviroc.
    Clinical drug investigation, 2011, Volume: 31, Issue:8

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Receptors, CCR5; Triazoles

2011
Tetrahydrofuran, tetrahydropyran, triazoles and related heterocyclic derivatives as HIV protease inhibitors.
    Future medicinal chemistry, 2011, Volume: 3, Issue:9

    Topics: Furans; Heterocyclic Compounds; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Pyrans; Structure-Activity Relationship; Triazoles

2011
CCR5 antagonism in HIV infection: current concepts and future opportunities.
    Annual review of medicine, 2012, Volume: 63

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Drug Discovery; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Receptors, CCR5; Triazoles

2012
Drug safety evaluation of maraviroc for the treatment of HIV infection.
    Expert opinion on drug safety, 2012, Volume: 11, Issue:1

    Topics: Animals; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Clinical Trials as Topic; Cyclohexanes; Drug Monitoring; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Time Factors; Triazoles

2012
Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the fetal compartment (placenta and amniotic fluid).
    Antiviral therapy, 2011, Volume: 16, Issue:8

    Topics: Adenine; Adult; Amniotic Fluid; Anti-HIV Agents; Cyclohexanes; Enfuvirtide; Female; Fetal Blood; Fetus; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV Integrase Inhibitors; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Maraviroc; Nevirapine; Organophosphonates; Peptide Fragments; Placenta; Pregnancy; Pregnancy Complications, Infectious; Pyrrolidinones; Raltegravir Potassium; Reverse Transcriptase Inhibitors; Tenofovir; Triazoles; Viral Load; Zidovudine

2011
[Methods for determination of HIV tropism and their clinical use].
    Enfermedades infecciosas y microbiologia clinica, 2011, Volume: 29 Suppl 5

    Topics: Algorithms; Anti-HIV Agents; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; Europe; Genes, env; Genotype; HIV Envelope Protein gp120; HIV Envelope Protein gp41; HIV Infections; HIV-1; Humans; Maraviroc; Peptide Fragments; Phenotype; Practice Guidelines as Topic; Receptors, CCR5; Receptors, CXCR4; Retrospective Studies; Triazoles; Viral Tropism; Virology; Virus Internalization

2011
CCR5 inhibitors: emergence, success, and challenges.
    Expert opinion on emerging drugs, 2012, Volume: 17, Issue:2

    Topics: Animals; Anti-HIV Agents; CCR5 Receptor Antagonists; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclohexanes; HIV Infections; Humans; Maraviroc; Receptors, CXCR4; Triazoles

2012
Clinical studies with chemokine receptor-5 (CCR5)-inhibitors.
    Current opinion in HIV and AIDS, 2012, Volume: 7, Issue:5

    Topics: Antibodies, Monoclonal; Antiviral Agents; CCR5 Receptor Antagonists; Coinfection; Cyclohexanes; Hepatitis C, Chronic; HIV; HIV Antibodies; HIV Infections; Humans; Maraviroc; Molecular Diagnostic Techniques; Triazoles; Viral Tropism; Virology

2012
The MOTIVATE trials: maraviroc therapy in antiretroviral treatment-experienced HIV-1-infected patients.
    Expert review of anti-infective therapy, 2012, Volume: 10, Issue:11

    Topics: Anti-Retroviral Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Maraviroc; Randomized Controlled Trials as Topic; Triazoles; Viral Tropism

2012
HIV-1 entry inhibitors: recent development and clinical use.
    Current opinion in virology, 2013, Volume: 3, Issue:1

    Topics: Antibodies, Monoclonal; Chemoprevention; Clinical Trials as Topic; Cyclohexanes; Disease Transmission, Infectious; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Organophosphates; Piperazines; Triazoles; Virus Internalization

2013
S-1360 Shionogi-GlaxoSmithKline.
    Current opinion in investigational drugs (London, England : 2000), 2003, Volume: 4, Issue:2

    Topics: Anti-HIV Agents; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Furans; HIV Infections; HIV Integrase Inhibitors; Humans; Triazoles

2003
A systematic review of the management of oral candidiasis associated with HIV/AIDS.
    SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging, 2002, Volume: 57, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Antifungal Agents; Candidiasis, Oral; Comorbidity; HIV Infections; Humans; Practice Guidelines as Topic; Treatment Outcome; Triazoles

2002
Serious doubts on safety and efficacy of CCR5 antagonists : CCR5 antagonists teeter on a knife-edge.
    Infection, 2006, Volume: 34, Issue:2

    Topics: Benzoates; CCR5 Receptor Antagonists; Clinical Trials as Topic; Clinical Trials, Phase II as Topic; Cyclohexanes; Diketopiperazines; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Piperazines; Pyrimidines; Spiro Compounds; Treatment Outcome; Triazoles

2006
The clinical pharmacology of antiretrovirals in development.
    Expert opinion on drug metabolism & toxicology, 2006, Volume: 2, Issue:3

    Topics: Animals; Anti-Retroviral Agents; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; Darunavir; Drug Evaluation, Preclinical; Drug Interactions; HIV Infections; HIV Integrase Inhibitors; HIV Protease Inhibitors; HIV-1; Humans; Maraviroc; Nitriles; Organic Chemicals; Protease Inhibitors; Pyridazines; Pyrimidines; Pyrrolidinones; Raltegravir Potassium; Receptors, CCR5; Reverse Transcriptase Inhibitors; Sulfonamides; Triazoles

2006
Coccidioidomycosis in persons infected with HIV-1.
    Annals of the New York Academy of Sciences, 2007, Volume: 1111

    Topics: Amphotericin B; Antifungal Agents; CD4-Positive T-Lymphocytes; Coccidioidomycosis; HIV Infections; HIV-1; Humans; Patient Compliance; Recurrence; Triazoles

2007
[Voriconazole as an effective therapy against pulmonary aspergillosis in a man with immunodeficiency virus-infection: a case report].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2007, Volume: 81, Issue:2

    Topics: Antifungal Agents; Aspergillosis; HIV Infections; Humans; Lung Diseases, Fungal; Male; Middle Aged; Pyrimidines; Triazoles; Voriconazole

2007
Assessing theoretical risk and benefit suggested by genetic association studies of CCR5: experience in a drug development programme for maraviroc.
    Antiviral therapy, 2007, Volume: 12, Issue:2

    Topics: Adult; Arthritis, Rheumatoid; CCR5 Receptor Antagonists; Cyclohexanes; Drug Design; Female; Genotype; Hepatitis C; HIV Fusion Inhibitors; HIV Infections; Humans; Male; Maraviroc; Multiple Sclerosis; Mutation; Pharmacogenetics; Receptors, CCR5; Risk Assessment; Risk Factors; Triazoles

2007
Maraviroc, a chemokine CCR5 receptor antagonist for the treatment of HIV infection and AIDS.
    Current opinion in investigational drugs (London, England : 2000), 2007, Volume: 8, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Animals; Anti-HIV Agents; Anti-Inflammatory Agents; Arthritis, Rheumatoid; CCR5 Receptor Antagonists; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclohexanes; HIV Infections; Humans; Maraviroc; Receptors, CCR5; Structure-Activity Relationship; Triazoles

2007
Maraviroc.
    Drugs, 2007, Volume: 67, Issue:15

    Topics: Animals; Anti-HIV Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclohexanes; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Maraviroc; Triazoles

2007
CCR5 antagonists in the treatment of treatment-experienced patients infected with CCR5 tropic HIV-1.
    European journal of medical research, 2007, Oct-15, Volume: 12, Issue:9

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; HIV Infections; HIV-1; Humans; Maraviroc; Piperazines; Pyrimidines; Triazoles

2007
CCR5 antagonists in the treatment of treatment-naive patients infected with CCR5 tropic HIV-1.
    European journal of medical research, 2007, Oct-15, Volume: 12, Issue:9

    Topics: Adolescent; Adult; Anti-HIV Agents; Benzoates; CCR5 Receptor Antagonists; Cyclohexanes; Diketopiperazines; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Piperazines; Pyrimidines; Randomized Controlled Trials as Topic; Spiro Compounds; Triazoles

2007
How will CCR5 antagonists influence the recommendations for the antiretroviral treatment of HIV-1 infection.
    European journal of medical research, 2007, Oct-15, Volume: 12, Issue:9

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Patient Selection; Practice Guidelines as Topic; Triazoles

2007
Treatment with CCR5 antagonists: which patient may have a benefit?
    European journal of medical research, 2007, Oct-15, Volume: 12, Issue:9

    Topics: Anti-Retroviral Agents; CCR5 Receptor Antagonists; Cyclohexanes; HIV Infections; HIV-1; Humans; Maraviroc; Patient Selection; Treatment Outcome; Triazoles

2007
Bilateral renal aspergillosis in a patient with AIDS: a case report and review of reported cases.
    AIDS patient care and STDs, 2008, Volume: 22, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Antiretroviral Therapy, Highly Active; Aspergillosis; Aspergillus fumigatus; HIV Infections; Humans; Kidney Diseases; Male; Pyrimidines; Radiography; Tomography Scanners, X-Ray Computed; Triazoles; Voriconazole

2008
Maraviroc.
    Drugs of today (Barcelona, Spain : 1998), 2007, Volume: 43, Issue:11

    Topics: Animals; Controlled Clinical Trials as Topic; Cyclohexanes; Drug Interactions; Drug Resistance, Viral; Drug Therapy, Combination; Female; Food-Drug Interactions; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Triazoles

2007
A population pharmacokinetic meta-analysis of maraviroc in healthy volunteers and asymptomatic HIV-infected subjects.
    British journal of clinical pharmacology, 2008, Volume: 65 Suppl 1

    Topics: Adolescent; Adult; Anti-HIV Agents; CCR5 Receptor Antagonists; Computer Simulation; Cyclohexanes; Female; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Models, Biological; Models, Statistical; Randomized Controlled Trials as Topic; Triazoles

2008
Population pharmacokinetic/pharmacodynamic analysis of CCR5 receptor occupancy by maraviroc in healthy subjects and HIV-positive patients.
    British journal of clinical pharmacology, 2008, Volume: 65 Suppl 1

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Computer Simulation; Cyclohexanes; HIV Infections; Humans; Maraviroc; Models, Biological; Models, Statistical; Randomized Controlled Trials as Topic; Triazoles; Viral Load

2008
Newer systemic antifungal drugs for the treatment of onychomycosis.
    Clinics in podiatric medicine and surgery, 1996, Volume: 13, Issue:4

    Topics: Aged; Antifungal Agents; Child; Enzyme Inhibitors; Female; Griseofulvin; HIV Infections; Humans; Imidazoles; Male; Naphthalenes; Onychomycosis; Terbinafine; Triazoles

1996

Trials

104 trial(s) available for triazoles and HIV Infections

ArticleYear
Removal of doravirine by haemodialysis in people living with HIV with end-stage renal disease.
    The Journal of antimicrobial chemotherapy, 2022, 06-29, Volume: 77, Issue:7

    Topics: Chromatography, Liquid; Dialysis Solutions; HIV Infections; Humans; Kidney Failure, Chronic; Male; Pyridones; Renal Dialysis; Tandem Mass Spectrometry; Triazoles

2022
Brief Report: Efficacy and Safety of Oral Islatravir Once Daily in Combination With Doravirine Through 96 Weeks for Treatment-Naive Adults With HIV-1 Infection Receiving Initial Treatment With Islatravir, Doravirine, and Lamivudine.
    Journal of acquired immune deficiency syndromes (1999), 2022, 09-01, Volume: 91, Issue:1

    Topics: Adult; Anti-HIV Agents; Deoxyadenosines; Drug Combinations; HIV Infections; HIV-1; Humans; Lamivudine; Pyridones; Reverse Transcriptase Inhibitors; RNA; Tenofovir; Triazoles

2022
Impact of antiretroviral therapy intensification with C-C motif chemokine receptor 5 antagonist maraviroc on HIV-associated neurocognitive impairment.
    AIDS (London, England), 2023, 11-01, Volume: 37, Issue:13

    Topics: Antiretroviral Therapy, Highly Active; Cyclohexanes; HIV Infections; Humans; Maraviroc; Triazoles

2023
Efficacy and Safety of Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (DOR/3TC/TDF) in Treatment-Naive Adults With HIV-1 and Transmitted Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutations.
    Journal of acquired immune deficiency syndromes (1999), 2019, 12-01, Volume: 82, Issue:4

    Topics: Adult; Anti-HIV Agents; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Pyridones; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir; Triazoles

2019
Doravirine versus ritonavir-boosted darunavir in antiretroviral-naive adults with HIV-1 (DRIVE-FORWARD): 96-week results of a randomised, double-blind, non-inferiority, phase 3 trial.
    The lancet. HIV, 2020, Volume: 7, Issue:1

    Topics: Adult; Anti-HIV Agents; Darunavir; Double-Blind Method; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Pyridones; Ritonavir; Triazoles; Young Adult

2020
Comparative Bioavailability of Oral Granule Formulations of the HIV Antiretroviral Drugs Doravirine, Lamivudine, and Tenofovir Disoproxil Fumarate.
    AAPS PharmSciTech, 2020, Feb-13, Volume: 21, Issue:3

    Topics: Adult; Anti-HIV Agents; Anti-Retroviral Agents; Biological Availability; Cross-Over Studies; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Pyridones; Reverse Transcriptase Inhibitors; Tablets; Tenofovir; Triazoles; Young Adult

2020
Twice-Daily Doravirine Overcomes the Interaction Effect from Once-Weekly Rifapentine and Isoniazid in Healthy Volunteers.
    Clinical and translational science, 2020, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Antitubercular Agents; Area Under Curve; Drug Administration Schedule; Drug Interactions; Female; Healthy Volunteers; HIV Infections; Humans; Isoniazid; Male; Middle Aged; Prospective Studies; Pyridones; Reverse Transcriptase Inhibitors; Rifampin; Triazoles; Tuberculosis; Young Adult

2020
Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (TDF) Versus Efavirenz/Emtricitabine/TDF in Treatment-naive Adults With Human Immunodeficiency Virus Type 1 Infection: Week 96 Results of the Randomized, Double-blind, Phase 3 DRIVE-AHEAD Noninferiority
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 07-01, Volume: 73, Issue:1

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Emtricitabine; Fumarates; HIV Infections; HIV-1; Humans; Lamivudine; Pyridones; Tenofovir; Treatment Outcome; Triazoles

2021
Efficacy, safety and central nervous system effects after switch from efavirenz/tenofovir/emtricitabine to doravirine/tenofovir/lamivudine.
    AIDS (London, England), 2021, 04-01, Volume: 35, Issue:5

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Central Nervous System; Cyclopropanes; Drug Combinations; Emtricitabine; Female; HIV Infections; Humans; Lamivudine; Male; Pyridones; Tenofovir; Treatment Outcome; Triazoles

2021
Brief Report: Switching to DOR/3TC/TDF Maintains HIV-1 Virologic Suppression Through Week 144 in the DRIVE-SHIFT Trial.
    Journal of acquired immune deficiency syndromes (1999), 2021, 06-01, Volume: 87, Issue:2

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Pyridones; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Triazoles; Weight Gain; Weight Loss

2021
Islatravir in combination with doravirine for treatment-naive adults with HIV-1 infection receiving initial treatment with islatravir, doravirine, and lamivudine: a phase 2b, randomised, double-blind, dose-ranging trial.
    The lancet. HIV, 2021, Volume: 8, Issue:6

    Topics: Adult; Anti-HIV Agents; Deoxyadenosines; Drug Dosage Calculations; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Pyridones; Triazoles; Young Adult

2021
Randomized controlled trial of the tolerability and completion of maraviroc compared with Kaletra® in combination with Truvada® for HIV post-exposure prophylaxis (MiPEP Trial).
    The Journal of antimicrobial chemotherapy, 2017, 06-01, Volume: 72, Issue:6

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cyclohexanes; Drug Combinations; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lopinavir; Male; Maraviroc; Medication Adherence; Post-Exposure Prophylaxis; Ritonavir; Triazoles; Young Adult

2017
Impact of intensified antiretroviral therapy during early HIV infection on gut immunology and inflammatory blood biomarkers.
    AIDS (London, England), 2017, 07-17, Volume: 31, Issue:11

    Topics: Adult; Anti-HIV Agents; Biomarkers; Canada; Cyclohexanes; Double-Blind Method; Drug Therapy, Combination; Fibrin Fibrinogen Degradation Products; Flow Cytometry; HIV Infections; Humans; Immunity, Mucosal; Inflammation; Intestinal Mucosa; Lymphocyte Activation; Male; Maraviroc; Middle Aged; Prospective Studies; Raltegravir Potassium; Th17 Cells; Treatment Outcome; Triazoles; Young Adult

2017
Week 96 results of the randomized, multicentre Maraviroc Switch (MARCH) study.
    HIV medicine, 2018, Volume: 19, Issue:1

    Topics: Adult; Antiretroviral Therapy, Highly Active; CCR5 Receptor Antagonists; Cyclohexanes; Drug Substitution; Drug-Related Side Effects and Adverse Reactions; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Maraviroc; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Triazoles; Viral Load

2018
Safety and Tolerability of Maraviroc-Containing Regimens to Prevent HIV Infection in Women: A Phase 2 Randomized Trial.
    Annals of internal medicine, 2017, Sep-19, Volume: 167, Issue:6

    Topics: Adolescent; Adult; Cyclohexanes; Double-Blind Method; Female; Follow-Up Studies; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Middle Aged; Patient Dropouts; Pre-Exposure Prophylaxis; Prospective Studies; Treatment Outcome; Triazoles; Young Adult

2017
Tissue Pharmacologic and Virologic Determinants of Duodenal and Rectal Gastrointestinal-Associated Lymphoid Tissue Immune Reconstitution in HIV-Infected Patients Initiating Antiretroviral Therapy.
    The Journal of infectious diseases, 2017, 10-17, Volume: 216, Issue:7

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclohexanes; Cyclopropanes; DNA, Viral; Duodenum; Female; HIV Infections; Humans; Lymphoid Tissue; Male; Maraviroc; Raltegravir Potassium; Rectum; RNA, Viral; Triazoles

2017
Switch to maraviroc with darunavir/r, both QD, in patients with suppressed HIV-1 was well tolerated but virologically inferior to standard antiretroviral therapy: 48-week results of a randomized trial.
    PloS one, 2017, Volume: 12, Issue:11

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cyclohexanes; Darunavir; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Ritonavir; Treatment Outcome; Triazoles; Viral Load

2017
Doravirine versus ritonavir-boosted darunavir in antiretroviral-naive adults with HIV-1 (DRIVE-FORWARD): 48-week results of a randomised, double-blind, phase 3, non-inferiority trial.
    The lancet. HIV, 2018, Volume: 5, Issue:5

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Darunavir; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Pyridones; Ritonavir; RNA, Viral; Treatment Outcome; Triazoles; Viral Load

2018
Evaluation of the Pharmacokinetic Interaction Between Doravirine and Methadone.
    Clinical pharmacology in drug development, 2020, Volume: 9, Issue:2

    Topics: Adult; Analgesics, Opioid; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Outcome Assessment, Health Care; Pyridones; Reverse Transcriptase Inhibitors; Triazoles

2020
Once-daily Doravirine for Initial Treatment of Adults Living With Human Immunodeficiency Virus-1: An Integrated Safety Analysis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 03-17, Volume: 70, Issue:7

    Topics: Adult; Anti-HIV Agents; Emtricitabine; HIV Infections; HIV-1; Humans; Pyridones; Tenofovir; Triazoles

2020
Once-daily Doravirine in Human Immunodeficiency Virus Type 1-Infected, Antiretroviral-naive Adults: An Integrated Efficacy Analysis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 03-17, Volume: 70, Issue:7

    Topics: Adult; Anti-HIV Agents; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Emtricitabine; HIV Infections; HIV-1; Humans; Lamivudine; Pyridones; Treatment Outcome; Triazoles

2020
Doravirine dose selection and 96-week safety and efficacy versus efavirenz in antiretroviral therapy-naive adults with HIV-1 infection in a Phase IIb trial.
    Antiviral therapy, 2019, Volume: 24, Issue:6

    Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Pyridones; Treatment Outcome; Triazoles; Viral Load; Young Adult

2019
The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: a randomized trial.
    Blood, 2013, Jun-06, Volume: 121, Issue:23

    Topics: Adult; CCR5 Receptor Antagonists; CD4-Positive T-Lymphocytes; Cyclohexanes; Female; Gastrointestinal Tract; Graft vs Host Disease; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Immunophenotyping; Lymphocyte Activation; Lymphoid Tissue; Male; Maraviroc; Middle Aged; Rectum; RNA, Viral; Triazoles; Viral Load

2013
Prediction of virological response and assessment of resistance emergence to the HIV-1 attachment inhibitor BMS-626529 during 8-day monotherapy with its prodrug BMS-663068.
    Journal of acquired immune deficiency syndromes (1999), 2013, Sep-01, Volume: 64, Issue:1

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Viral; Female; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Mutation, Missense; Organophosphates; Piperazines; Prodrugs; RNA, Viral; Treatment Outcome; Triazoles; Viral Load

2013
Safety and immunovirologic outcomes with maraviroc combination regimens in patients with a history of past treatment failures and virologic resistance in Brazil: an open-label, multicenter phase 3b study.
    AIDS research and human retroviruses, 2013, Volume: 29, Issue:9

    Topics: Adult; Anti-HIV Agents; Brazil; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Darunavir; Drug Therapy, Combination; Female; HIV Fusion Inhibitors; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Maraviroc; Middle Aged; Protease Inhibitors; Pyrrolidinones; Raltegravir Potassium; Reverse Transcriptase Inhibitors; Sulfonamides; Treatment Failure; Triazoles; Viral Load; Young Adult

2013
Genotypic analysis of the V3 region of HIV from virologic nonresponders to maraviroc-containing regimens reveals distinct patterns of failure.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12

    Topics: Adolescent; Adult; Aged; CCR5 Receptor Antagonists; Cyclohexanes; Female; Gene Expression; Genotype; High-Throughput Nucleotide Sequencing; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Peptide Fragments; Receptors, CCR5; Receptors, CXCR4; Treatment Failure; Triazoles; Viral Tropism

2013
Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection.
    AIDS (London, England), 2013, Jul-31, Volume: 27, Issue:12

    Topics: Adult; Anti-Retroviral Agents; Bacteria; Bacterial Translocation; Biota; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cyclohexanes; Double-Blind Method; Drug Therapy, Combination; Gastrointestinal Tract; HIV Infections; Humans; Lactobacillales; Male; Maraviroc; Middle Aged; Placebos; Rectum; Triazoles; Young Adult

2013
Intensification of a raltegravir-based regimen with maraviroc in early HIV-1 infection.
    AIDS (London, England), 2014, Jan-28, Volume: 28, Issue:3

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cyclohexanes; DNA, Viral; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Prospective Studies; Pyrrolidinones; Raltegravir Potassium; RNA, Viral; Treatment Outcome; Triazoles; Viral Load

2014
Maraviroc as intensification strategy in HIV-1 positive patients with deficient immunological response: an Italian randomized clinical trial.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Biomarkers; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Immunocompromised Host; Interleukin-7; Ki-67 Antigen; Male; Maraviroc; Middle Aged; RNA, Viral; Treatment Outcome; Triazoles; Viral Load

2013
Dynamics of the HIV-1 latent reservoir after discontinuation of the intensification of antiretroviral treatment: results of two clinical trials.
    AIDS (London, England), 2013, Aug-24, Volume: 27, Issue:13

    Topics: Adult; Anti-Retroviral Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Pilot Projects; Pyrrolidinones; Raltegravir Potassium; Triazoles; Virus Latency

2013
Five-year safety evaluation of maraviroc in HIV-1-infected treatment-experienced patients.
    Journal of acquired immune deficiency syndromes (1999), 2014, Jan-01, Volume: 65, Issue:1

    Topics: Adult; CCR5 Receptor Antagonists; Cyclohexanes; Double-Blind Method; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Survival Analysis; Time Factors; Triazoles

2014
A randomized open-label study of 3- versus 5-drug combination antiretroviral therapy in newly HIV-1-infected individuals.
    Journal of acquired immune deficiency syndromes (1999), 2014, Jun-01, Volume: 66, Issue:2

    Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cyclohexanes; DNA, Viral; Drug Combinations; Endpoint Determination; HIV Infections; Humans; Longitudinal Studies; Male; Maraviroc; Middle Aged; Pyrrolidinones; Raltegravir Potassium; RNA, Viral; Triazoles; Viral Load; Viremia

2014
Effect of maraviroc intensification on HIV-1-specific T cell immunity in recently HIV-1-infected individuals.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Anti-Retroviral Agents; Cyclohexanes; Cytokines; Enzyme-Linked Immunospot Assay; Flow Cytometry; HIV Infections; HIV-1; Humans; Immunity, Cellular; Maraviroc; Receptors, CCR5; Statistics, Nonparametric; T-Lymphocytes; Triazoles; Virus Internalization

2014
Maraviroc plus raltegravir failed to maintain virological suppression in HIV-infected patients with lipohypertrophy: results from the ROCnRAL ANRS 157 study.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:6

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Lipodystrophy; Male; Maraviroc; Middle Aged; Pyrrolidinones; Raltegravir Potassium; Risk Factors; Treatment Failure; Triazoles; Viral Load

2014
Virological response to short-course maraviroc monotherapy does not predict viral tropism in HIV-1-infected treatment-naive patients.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:7

    Topics: Adult; Anti-HIV Agents; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Pilot Projects; Treatment Outcome; Triazoles; Viral Load; Viral Tropism; Young Adult

2014
Four-year outcome of a PI and NRTI-sparing salvage regimen: maraviroc, raltegravir, etravirine.
    The new microbiologica, 2014, Volume: 37, Issue:2

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Blood Cell Count; Cyclohexanes; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Maraviroc; Middle Aged; Nitriles; Pyridazines; Pyrimidines; Pyrrolidinones; Raltegravir Potassium; Treatment Outcome; Triazoles

2014
Efficacy and safety of maraviroc vs. efavirenz in treatment-naive patients with HIV-1: 5-year findings.
    AIDS (London, England), 2014, Mar-13, Volume: 28, Issue:5

    Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclohexanes; Cyclopropanes; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Treatment Outcome; Triazoles; Viral Load; Young Adult

2014
Maintenance of virologic efficacy and decrease in levels of β2-microglobulin, soluble CD40L and soluble CD14 after switching previously treated HIV-infected patients to an NRTI-sparing dual therapy.
    Antiviral research, 2014, Volume: 111

    Topics: Adult; beta 2-Microglobulin; CD4-Positive T-Lymphocytes; CD40 Ligand; Cyclohexanes; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lipopolysaccharide Receptors; Male; Maraviroc; Middle Aged; Reverse Transcriptase Inhibitors; Triazoles

2014
Effect of maraviroc on non-R5 tropic HIV-1: refined analysis of subjects from the phase IIb study A4001029.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2015, Volume: 21, Issue:1

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; HIV Infections; HIV-1; Humans; Maraviroc; Mutation; Triazoles; Viral Tropism

2015
Maraviroc 150 mg daily plus lopinavir/ritonavir, a nucleoside/nucleotide reverse transcriptase inhibitor-sparing regimen for HIV-infected naive patients: 48-week final results of VEMAN study.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2015, Volume: 21, Issue:5

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cyclohexanes; DNA, Viral; Drug Combinations; Female; HIV Infections; HIV-1; Humans; Lopinavir; Male; Maraviroc; Prospective Studies; Ritonavir; Treatment Outcome; Triazoles; Viral Load

2015
Plasma concentrations of maraviroc and raltegravir after dual therapy in patients with long-term suppressed viraemia: ROCnRAL ANRS 157 study.
    The Journal of antimicrobial chemotherapy, 2015, Volume: 70, Issue:8

    Topics: Anti-HIV Agents; Chromatography, Liquid; Cyclohexanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Plasma; Raltegravir Potassium; Tandem Mass Spectrometry; Triazoles

2015
Sitagliptin Reduces Inflammation and Chronic Immune Cell Activation in HIV+ Adults With Impaired Glucose Tolerance.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:7

    Topics: Adipokines; Adult; Chemokines; Endothelial Progenitor Cells; Female; Glucose Intolerance; HIV Infections; HIV-1; Humans; Hypoglycemic Agents; Inflammation; Lymphocyte Activation; Male; Middle Aged; Pyrazines; Sitagliptin Phosphate; Triazoles

2015
Dynamics of adaptive and innate immunity in patients treated during primary human immunodeficiency virus infection: results from Maraviroc in HIV Acute Infection (MAIN) randomized clinical trial.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2015, Volume: 21, Issue:9

    Topics: Adaptive Immunity; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cyclohexanes; Dendritic Cells; Female; HIV; HIV Infections; Humans; Immunity, Innate; Lymphocyte Subsets; Male; Maraviroc; Prospective Studies; Triazoles

2015
Less Bone Loss With Maraviroc- Versus Tenofovir-Containing Antiretroviral Therapy in the AIDS Clinical Trials Group A5303 Study.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015, Oct-01, Volume: 61, Issue:7

    Topics: Adult; Anti-HIV Agents; Bone Density; Cyclohexanes; Female; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Pelvic Bones; Tenofovir; Triazoles

2015
Maraviroc Pharmacokinetics in HIV-1-Infected Pregnant Women.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015, Nov-15, Volume: 61, Issue:10

    Topics: Adult; Anti-HIV Agents; Blood Chemical Analysis; Cyclohexanes; Europe; Female; HIV Infections; Humans; Maraviroc; Pregnancy; Pregnancy Complications, Infectious; Triazoles; United States; Young Adult

2015
Maraviroc Intensification of cART in Patients with Suboptimal Immunological Recovery: A 48-Week, Placebo-Controlled Randomized Trial.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CCR5 Receptor Antagonists; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclohexanes; Double-Blind Method; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Lymphocyte Count; Male; Maraviroc; Middle Aged; Receptors, CCR5; Time Factors; Treatment Outcome; Triazoles

2015
Missing CD4+ cell response in randomized clinical trials of maraviroc and dolutegravir.
    HIV clinical trials, 2015, Volume: 16, Issue:5

    Topics: Adult; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cyclohexanes; Data Interpretation, Statistical; Datasets as Topic; Double-Blind Method; Female; Heterocyclic Compounds, 3-Ring; HIV Infections; HIV Integrase Inhibitors; HIV-1; Humans; Male; Maraviroc; Models, Statistical; Oxazines; Piperazines; Pyridones; Triazoles; United States

2015
A randomized, double-blind, placebo-controlled, short-term monotherapy study of doravirine in treatment-naive HIV-infected individuals.
    AIDS (London, England), 2016, Jan-02, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Anti-HIV Agents; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Male; Middle Aged; Placebos; Plasma; Pyridones; RNA, Viral; Treatment Outcome; Triazoles; Young Adult

2016
Virological factors associated with outcome of dual maraviroc/raltegravir therapy (ANRS-157 trial).
    The Journal of antimicrobial chemotherapy, 2015, Volume: 70, Issue:12

    Topics: Anti-HIV Agents; Cyclohexanes; HIV Infections; HIV-1; Maraviroc; Raltegravir Potassium; Risk Factors; Treatment Failure; Triazoles; Viral Load

2015
Virologic and immunologic effects of adding maraviroc to suppressive antiretroviral therapy in individuals with suboptimal CD4+ T-cell recovery.
    AIDS (London, England), 2015, Oct-23, Volume: 29, Issue:16

    Topics: Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Prospective Studies; Treatment Outcome; Triazoles; Viral Load

2015
Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial.
    PLoS pathogens, 2016, Volume: 12, Issue:1

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CCR5 Receptor Antagonists; Chromatography, High Pressure Liquid; Cyclohexanes; Cyclopropanes; Drug Combinations; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; HIV Infections; HIV Integrase Inhibitors; Humans; Immunity, Mucosal; Lymphocyte Activation; Male; Maraviroc; Pilot Projects; Raltegravir Potassium; T-Lymphocyte Subsets; Triazoles

2016
Maraviroc-intensified combined antiretroviral therapy improves cognition in virally suppressed HIV-associated neurocognitive disorder.
    AIDS (London, England), 2016, Feb-20, Volume: 30, Issue:4

    Topics: Aged; AIDS Dementia Complex; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Cognition; Cyclohexanes; Double-Blind Method; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Pilot Projects; Prospective Studies; Treatment Outcome; Triazoles

2016
Adherence and Acceptability of a Multidrug Vaginal Ring for HIV Prevention in a Phase I Study in the United States.
    AIDS and behavior, 2016, Volume: 20, Issue:11

    Topics: Adult; Anti-HIV Agents; Contraceptive Devices, Female; Cyclohexanes; Double-Blind Method; Drug Therapy, Combination; Feasibility Studies; Female; HIV Infections; Humans; Interview, Psychological; Maraviroc; Medication Adherence; Patient Acceptance of Health Care; Pre-Exposure Prophylaxis; Program Evaluation; Pyrimidines; South Africa; Text Messaging; Triazoles

2016
Model-Based Phase 3 Dose Selection for HIV-1 Attachment Inhibitor Prodrug BMS-663068 in HIV-1-Infected Patients: Population Pharmacokinetics/Pharmacodynamics of the Active Moiety, BMS-626529.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Drug Administration Schedule; Female; HIV Infections; Humans; Inhibitory Concentration 50; Male; Middle Aged; Organophosphates; Piperazines; Prodrugs; Triazoles

2016
Maraviroc, as a Switch Option, in HIV-1-infected Individuals With Stable, Well-controlled HIV Replication and R5-tropic Virus on Their First Nucleoside/Nucleotide Reverse Transcriptase Inhibitor Plus Ritonavir-boosted Protease Inhibitor Regimen: Week 48 R
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, 07-01, Volume: 63, Issue:1

    Topics: Adult; Comorbidity; Cyclohexanes; Female; HIV Fusion Inhibitors; HIV Infections; HIV Protease Inhibitors; Humans; Male; Maraviroc; Middle Aged; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Outcome; Triazoles; Viral Load; Virus Replication

2016
Differential CD4+ cell count increase and CD4+ :  CD8+ ratio normalization with maraviroc compared with tenofovir.
    AIDS (London, England), 2016, 08-24, Volume: 30, Issue:13

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-CD8 Ratio; Cyclohexanes; Darunavir; Double-Blind Method; Emtricitabine; Female; Flow Cytometry; HIV Infections; Humans; Male; Maraviroc; Placebos; Prospective Studies; Tenofovir; Treatment Outcome; Triazoles

2016
Neurocognition with maraviroc compared with tenofovir in HIV.
    AIDS (London, England), 2016, 09-24, Volume: 30, Issue:15

    Topics: Adult; AIDS-Related Complex; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cognition; Cyclohexanes; Double-Blind Method; Female; HIV Infections; Humans; Male; Maraviroc; Neuropsychological Tests; Placebos; Tenofovir; Treatment Outcome; Triazoles; United States

2016
Pharmacodynamic correlations using fresh and cryopreserved tissue following use of vaginal rings containing dapivirine and/or maraviroc in a randomized, placebo controlled trial.
    Medicine, 2016, Volume: 95, Issue:28

    Topics: Administration, Intravaginal; Adult; Biopsy; Cervix Uteri; Contraceptive Devices, Female; Cryopreservation; Cyclohexanes; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; In Vitro Techniques; Maraviroc; Pyrimidines; Sexually Transmitted Diseases, Viral; Triazoles; United States

2016
Maraviroc/raltegravir simplification strategy following 6 months of quadruple therapy with tenofovir/emtricitabine/maraviroc/raltegravir in treatment-naive HIV patients.
    The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:11

    Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cyclohexanes; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Maintenance Chemotherapy; Male; Maraviroc; Middle Aged; Raltegravir Potassium; Tenofovir; Treatment Outcome; Triazoles; Viral Load; Young Adult

2016
48 week outcomes of maraviroc-containing regimens following the genotypic or Trofile assay in HIV-1 failing subjects: the OSCAR Study.
    The new microbiologica, 2016, Volume: 39, Issue:3

    Topics: Adult; Anti-HIV Agents; Cyclohexanes; Drug Administration Schedule; Female; Genotype; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Treatment Failure; Triazoles; Viral Tropism

2016
Brief Report: Pharmacokinetic/Pharmacodynamic Investigation of Single-Dose Oral Maraviroc in the Context of HIV-1 Pre-exposure Prophylaxis.
    Journal of acquired immune deficiency syndromes (1999), 2016, 11-01, Volume: 73, Issue:3

    Topics: Administration, Oral; Adult; CCR5 Receptor Antagonists; Cyclohexanes; Female; Healthy Volunteers; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Intestinal Mucosa; Male; Maraviroc; Models, Biological; Pre-Exposure Prophylaxis; Randomized Controlled Trials as Topic; Rectum; Saliva; Treatment Outcome; Triazoles; Urethra; Vagina

2016
Phase 2 Study of the Safety and Tolerability of Maraviroc-Containing Regimens to Prevent HIV Infection in Men Who Have Sex With Men (HPTN 069/ACTG A5305).
    The Journal of infectious diseases, 2017, Jan-15, Volume: 215, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; Disease Transmission, Infectious; Double-Blind Method; HIV Infections; Homosexuality, Male; Humans; Male; Maraviroc; Middle Aged; Pre-Exposure Prophylaxis; Prospective Studies; Triazoles; Young Adult

2017
A randomized controlled clinical trial on the impact of CCR5 blockade with maraviroc in early infection on T-cell dynamics.
    Medicine, 2016, Volume: 95, Issue:44

    Topics: Adult; CCR5 Receptor Antagonists; Cyclohexanes; Double-Blind Method; Female; HIV Infections; Humans; Male; Maraviroc; T-Lymphocytes; Time Factors; Triazoles

2016
Maraviroc in addition to cART during primary HIV infection: Results from MAIN randomized clinical trial and 96-weeks follow-up.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2016, Volume: 85

    Topics: Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Female; Follow-Up Studies; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Nerve Tissue Proteins; RNA, Viral; Treatment Outcome; Triazoles; Viral Load

2016
Hepatic safety of maraviroc in patients with HIV-1 and hepatitis C and/or B virus: 144-week results from a randomized, placebo-controlled trial.
    Antiviral therapy, 2017, Volume: 22, Issue:3

    Topics: Adult; Aged; Antiretroviral Therapy, Highly Active; Coinfection; Cyclohexanes; Female; Hepatitis B; Hepatitis C; HIV Fusion Inhibitors; HIV Infections; Humans; Liver; Liver Function Tests; Male; Maraviroc; Middle Aged; Treatment Outcome; Triazoles; Viral Load

2017
Maraviroc for previously treated patients with R5 HIV-1 infection.
    The New England journal of medicine, 2008, Oct-02, Volume: 359, Issue:14

    Topics: Adult; Aged; Anti-Retroviral Agents; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Double-Blind Method; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; RNA, Viral; Treatment Failure; Triazoles; Viral Load

2008
Maraviroc approved for use in treatment-experienced CCR5-tropic HIV-1.
    AIDS alert, 2009, Volume: 24, Issue:1

    Topics: CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Double-Blind Method; Drug Approval; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Placebos; Triazoles; United States; United States Food and Drug Administration; Viral Load

2009
A double-blind, placebo-controlled trial of maraviroc in treatment-experienced patients infected with non-R5 HIV-1.
    The Journal of infectious diseases, 2009, Jun-01, Volume: 199, Issue:11

    Topics: Adult; Aged; Cyclohexanes; Double-Blind Method; Female; Genotype; HIV; HIV Fusion Inhibitors; HIV Infections; Humans; Least-Squares Analysis; Male; Maraviroc; Middle Aged; Patient Selection; Phenotype; Placebos; Triazoles; Viral Load; Young Adult

2009
96-Week MERIT ES analysis shows efficacy of Celsentri=Selzentry.
    AIDS patient care and STDs, 2009, Volume: 23, Issue:8

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Cyclopropanes; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Lamivudine; Maraviroc; Reverse Transcriptase Inhibitors; Time Factors; Treatment Outcome; Triazoles; Zidovudine

2009
Maraviroc versus efavirenz, both in combination with zidovudine-lamivudine, for the treatment of antiretroviral-naive subjects with CCR5-tropic HIV-1 infection.
    The Journal of infectious diseases, 2010, Mar-15, Volume: 201, Issue:6

    Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Antiviral Agents; Benzoxazines; CCR5 Receptor Antagonists; Cyclohexanes; Cyclopropanes; Double-Blind Method; Drug Combinations; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Maraviroc; Middle Aged; Receptors, CCR5; Treatment Outcome; Triazoles; Viral Load; Viral Tropism; Young Adult; Zidovudine

2010
Raltegravir plasma concentrations in treatment-experienced patients receiving salvage regimens based on raltegravir with and without maraviroc coadministration.
    The Annals of pharmacotherapy, 2010, Volume: 44, Issue:5

    Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Cyclohexanes; Drug Administration Schedule; Drug Interactions; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Pyrrolidinones; Raltegravir Potassium; Salvage Therapy; Triazoles; Young Adult

2010
Hemodynamic effects of single-dose vardenafil in subjects receiving maraviroc.
    Journal of acquired immune deficiency syndromes (1999), 2010, Volume: 54, Issue:3

    Topics: Adolescent; Adult; Blood Pressure; Cross-Over Studies; Cyclohexanes; Erectile Dysfunction; HIV Fusion Inhibitors; HIV Infections; Humans; Imidazoles; Male; Maraviroc; Middle Aged; Phosphodiesterase Inhibitors; Piperazines; Single-Blind Method; Sulfones; Triazines; Triazoles; Vardenafil Dihydrochloride; Vasodilator Agents; Young Adult

2010
Maraviroc in treatment-experienced patients with HIV-1 infection - experience from routine clinical practice.
    European journal of medical research, 2010, Jun-28, Volume: 15, Issue:6

    Topics: Antiviral Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Resistance, Viral; Drug Therapy, Combination; Female; Gene Expression Regulation, Viral; Genotype; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Prospective Studies; Salvage Therapy; Treatment Outcome; Triazoles; Viral Tropism; Virus Internalization; Virus Replication

2010
Two-year safety and virologic efficacy of maraviroc in treatment-experienced patients with CCR5-tropic HIV-1 infection: 96-week combined analysis of MOTIVATE 1 and 2.
    Journal of acquired immune deficiency syndromes (1999), 2010, Dec-15, Volume: 55, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cyclohexanes; Double-Blind Method; Female; Follow-Up Studies; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Triazoles

2010
Treatment intensification has no effect on the HIV-1 central nervous system infection in patients on suppressive antiretroviral therapy.
    Journal of acquired immune deficiency syndromes (1999), 2010, Dec-15, Volume: 55, Issue:5

    Topics: Adult; Albumins; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Central Nervous System Infections; Cross-Over Studies; Cyclohexanes; Enfuvirtide; Female; HIV Envelope Protein gp41; HIV Infections; HIV-1; Humans; Immunoglobulin G; Lopinavir; Male; Maraviroc; Middle Aged; Neopterin; Peptide Fragments; Polymerase Chain Reaction; Ritonavir; RNA, Viral; Triazoles; Viral Load; Viremia; Virus Replication

2010
Effects of maraviroc and efavirenz on markers of immune activation and inflammation and associations with CD4+ cell rises in HIV-infected patients.
    PloS one, 2010, Oct-06, Volume: 5, Issue:10

    Topics: Alkynes; Benzoxazines; Case-Control Studies; CD4 Lymphocyte Count; Cyclohexanes; Cyclopropanes; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Receptors, CCR5; Reverse Transcriptase Inhibitors; Triazoles; Viral Load

2010
Durability and safety of a novel salvage therapy in R5-tropic HIV-infected patients: maraviroc, raltegravir, etravirine.
    Journal of acquired immune deficiency syndromes (1999), 2011, Volume: 56, Issue:4

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cyclohexanes; Female; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Nitriles; Pyridazines; Pyrimidines; Pyrrolidinones; Raltegravir Potassium; RNA, Viral; Salvage Therapy; Treatment Outcome; Triazoles; Viral Load

2011
Deep V3 sequencing for HIV type 1 tropism in treatment-naive patients: a reanalysis of the MERIT trial of maraviroc.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2011, Volume: 53, Issue:7

    Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclohexanes; Cyclopropanes; Female; High-Throughput Nucleotide Sequencing; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Retrospective Studies; Treatment Failure; Treatment Outcome; Triazoles; Viral Tropism; Young Adult

2011
CNS effects of a CCR5 inhibitor in HIV-infected subjects: a pharmacokinetic and cerebral metabolite study.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:1

    Topics: Adult; Anti-HIV Agents; Brain; Brain Chemistry; CCR5 Receptor Antagonists; Cerebrospinal Fluid; Cyclohexanes; Female; HIV Infections; Humans; Magnetic Resonance Spectroscopy; Male; Maraviroc; Middle Aged; Plasma; Triazoles

2012
[Our experience with maraviroc treatment in HIV positive patients].
    Casopis lekaru ceskych, 2011, Volume: 150, Issue:8

    Topics: CD4 Lymphocyte Count; Cyclohexanes; Female; HIV Fusion Inhibitors; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Triazoles; Viral Load

2011
Intensification of antiretroviral therapy with a CCR5 antagonist in patients with chronic HIV-1 infection: effect on T cells latently infected.
    PloS one, 2011, Volume: 6, Issue:12

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bacteria; CCR5 Receptor Antagonists; CD8-Positive T-Lymphocytes; Chronic Disease; Cyclohexanes; Disease Reservoirs; DNA, Circular; Female; HIV Infections; HIV-1; Humans; Immunologic Memory; Lymphocyte Activation; Male; Maraviroc; Middle Aged; Plasmids; Receptors, CCR5; T-Lymphocyte Subsets; T-Lymphocytes; Triazoles; Viremia

2011
T-cell changes after a short-term exposure to maraviroc in HIV-infected patients are related to antiviral activity.
    The Journal of infection, 2012, Volume: 64, Issue:4

    Topics: Adult; Anti-HIV Agents; CCR5 Receptor Antagonists; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclohexanes; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; T-Lymphocyte Subsets; T-Lymphocytes; Treatment Outcome; Triazoles; Viral Load

2012
HIV-1 tropism evolution after short-term maraviroc monotherapy in HIV-1-infected patients.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:7

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; CD4-Positive T-Lymphocytes; Cyclohexanes; HIV Infections; Humans; Maraviroc; Receptors, CXCR4; Triazoles; Viral Load

2012
From in vitro EC₅₀ to in vivo dose-response for antiretrovirals using an HIV disease model. Part I: a framework.
    Journal of pharmacokinetics and pharmacodynamics, 2012, Volume: 39, Issue:4

    Topics: Adenine; Anti-HIV Agents; Cyclohexanes; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heterocyclic Compounds, 3-Ring; HIV Infections; HIV-1; Humans; Inhibitory Concentration 50; Male; Maraviroc; Models, Biological; Nitriles; Organophosphonates; Oxazines; Piperazines; Pyridazines; Pyridones; Pyrimidines; RNA, Viral; Tenofovir; Triazoles

2012
A pilot trial of adding maraviroc to suppressive antiretroviral therapy for suboptimal CD4⁺ T-cell recovery despite sustained virologic suppression: ACTG A5256.
    The Journal of infectious diseases, 2012, Aug-15, Volume: 206, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Triazoles; Viral Load; Young Adult

2012
CCR5 antagonism impacts vaccination response and immune profile in HIV-1 infection.
    Molecular medicine (Cambridge, Mass.), 2012, Oct-24, Volume: 18

    Topics: AIDS Vaccines; CCR5 Receptor Antagonists; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Immunity; Immunity, Cellular; Immunity, Humoral; Immunophenotyping; Male; Maraviroc; Middle Aged; Receptors, CCR5; T-Lymphocytes; Treatment Outcome; Triazoles; Vaccination

2012
Maraviroc intensification of stable antiviral therapy in HIV-1-infected patients with poor immune restoration: MARIMUNO-ANRS 145 study.
    Journal of acquired immune deficiency syndromes (1999), 2012, Dec-15, Volume: 61, Issue:5

    Topics: Aged; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-CD8 Ratio; Cyclohexanes; Drug Interactions; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Prospective Studies; Triazoles; Viral Load

2012
A genotypic test for HIV-1 tropism combining Sanger sequencing with ultradeep sequencing predicts virologic response in treatment-experienced patients.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Adult; Aged; Algorithms; Anti-HIV Agents; Biological Assay; Biomarkers, Pharmacological; CCR5 Receptor Antagonists; Cyclohexanes; Female; Genotyping Techniques; High-Throughput Nucleotide Sequencing; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Predictive Value of Tests; Receptors, CCR5; Receptors, CXCR4; Retrospective Studies; Triazoles; Viral Tropism

2012
Population-based sequencing of the V3-loop can predict the virological response to maraviroc in treatment-naive patients of the MERIT trial.
    Journal of acquired immune deficiency syndromes (1999), 2012, Nov-01, Volume: 61, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Cyclohexanes; Drug Combinations; Drug Therapy, Combination; Female; Genotype; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Lamivudine; Male; Maraviroc; Middle Aged; Polymerase Chain Reaction; Retrospective Studies; Sequence Analysis, DNA; Triazoles; Viral Load; Viral Tropism; Young Adult; Zidovudine

2012
Maraviroc once-daily nucleoside analog-sparing regimen in treatment-naive patients: randomized, open-label pilot study.
    Journal of acquired immune deficiency syndromes (1999), 2013, Feb-01, Volume: 62, Issue:2

    Topics: Adenine; Adolescent; Adult; Aged; Anti-HIV Agents; Atazanavir Sulfate; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Oligopeptides; Organophosphonates; Pilot Projects; Pyridines; Ritonavir; RNA, Viral; Tenofovir; Triazoles; Viral Load; Young Adult

2013
Dipeptidyl peptidase IV inhibition does not adversely affect immune or virological status in HIV infected men and women: a pilot safety study.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:2

    Topics: Adolescent; Adult; Aged; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Female; HIV Infections; HIV Seropositivity; Humans; Male; Middle Aged; Pilot Projects; Pyrazines; RNA, Viral; Sitagliptin Phosphate; Triazoles

2013
Switching the third drug of antiretroviral therapy to maraviroc in aviraemic subjects: a pilot, prospective, randomized clinical trial.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:6

    Topics: Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cyclohexanes; Dyslipidemias; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Hypolipidemic Agents; Intention to Treat Analysis; Male; Maraviroc; Middle Aged; Pilot Projects; Prospective Studies; Triazoles; Triglycerides; Viral Tropism

2013
Pharmacokinetics and short-term safety of etravirine in combination with fluconazole or voriconazole in HIV-negative volunteers.
    Journal of clinical pharmacology, 2013, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Anti-HIV Agents; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Cross-Over Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Female; Fluconazole; Genotype; HIV Infections; Humans; Male; Middle Aged; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Triazoles; Voriconazole; Young Adult

2013
A pharmacokinetic-pharmacodynamic disease model to predict in vivo antiviral activity of maraviroc.
    Clinical pharmacology and therapeutics, 2005, Volume: 78, Issue:5

    Topics: Adult; Algorithms; Anti-HIV Agents; CCR5 Receptor Antagonists; Computer Simulation; Cyclohexanes; Dose-Response Relationship, Drug; HIV Infections; HIV-1; Humans; Male; Maraviroc; Models, Biological; Models, Statistical; Predictive Value of Tests; RNA, Viral; Triazoles; Viral Load; Virus Replication

2005
A pharmacokinetic-pharmacodynamic model to optimize the phase IIa development program of maraviroc.
    Journal of acquired immune deficiency syndromes (1999), 2006, Volume: 42, Issue:2

    Topics: Anti-HIV Agents; Computer Simulation; Cyclohexanes; Dose-Response Relationship, Drug; Food; HIV Infections; HIV-1; Humans; Maraviroc; Monte Carlo Method; Placebos; RNA, Viral; Triazoles; Viral Load

2006
Emergence of CXCR4-using human immunodeficiency virus type 1 (HIV-1) variants in a minority of HIV-1-infected patients following treatment with the CCR5 antagonist maraviroc is from a pretreatment CXCR4-using virus reservoir.
    Journal of virology, 2006, Volume: 80, Issue:10

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Cell Line; Clone Cells; Cyclohexanes; Evolution, Molecular; Genes, env; Genetic Variation; HIV Envelope Protein gp160; HIV Infections; HIV-1; Humans; Maraviroc; Phylogeny; Receptors, CCR5; Receptors, CXCR4; Recombination, Genetic; Triazoles

2006
Assessment of the pharmacokinetics, safety and tolerability of maraviroc, a novel CCR5 antagonist, in healthy volunteers.
    British journal of clinical pharmacology, 2008, Volume: 65 Suppl 1

    Topics: Administration, Oral; Adolescent; Adult; Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; Female; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Statistics as Topic; Triazoles

2008
Effect of maraviroc on the pharmacokinetics of midazolam, lamivudine/zidovudine, and ethinyloestradiol/levonorgestrel in healthy volunteers.
    British journal of clinical pharmacology, 2008, Volume: 65 Suppl 1

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Anti-HIV Agents; CCR5 Receptor Antagonists; Contraceptives, Oral; Cyclohexanes; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Ethinyl Estradiol; Female; HIV Infections; Humans; Lamivudine; Levonorgestrel; Male; Maraviroc; Midazolam; Middle Aged; Statistics as Topic; Triazoles; Zidovudine

2008
Effects of CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers.
    British journal of clinical pharmacology, 2008, Volume: 65 Suppl 1

    Topics: Adolescent; Anti-HIV Agents; Antifungal Agents; Atazanavir Sulfate; CCR5 Receptor Antagonists; Cyclohexanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Ketoconazole; Male; Maraviroc; Middle Aged; Oligopeptides; Pyridines; Saquinavir; Statistics as Topic; Triazoles

2008
Effects of CYP3A4 inducers with and without CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers.
    British journal of clinical pharmacology, 2008, Volume: 65 Suppl 1

    Topics: Adolescent; Adult; CCR5 Receptor Antagonists; Cyclohexanes; Cytochrome P-450 CYP3A; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Male; Maraviroc; Middle Aged; Statistics as Topic; Triazoles

2008
The effects of cotrimoxazole or tenofovir co-administration on the pharmacokinetics of maraviroc in healthy volunteers.
    British journal of clinical pharmacology, 2008, Volume: 65 Suppl 1

    Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Anti-Infective Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Organophosphonates; Receptors, CCR5; Statistics as Topic; Tenofovir; Triazoles; Trimethoprim, Sulfamethoxazole Drug Combination

2008
A novel probe drug interaction study to investigate the effect of selected antiretroviral combinations on the pharmacokinetics of a single oral dose of maraviroc in HIV-positive subjects.
    British journal of clinical pharmacology, 2008, Volume: 65 Suppl 1

    Topics: Administration, Oral; Adolescent; Adult; Anti-Retroviral Agents; Area Under Curve; CCR5 Receptor Antagonists; Cyclohexanes; Drug Interactions; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Receptors, CCR5; Triazoles

2008
Maraviroc: integration of a new antiretroviral drug class into clinical practice.
    The Journal of antimicrobial chemotherapy, 2008, Volume: 61, Issue:6

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Double-Blind Method; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Triazoles; Virology

2008
Treatment of coccidioidomycosis with SCH 39304.
    Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1994, Volume: 32, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antifungal Agents; Coccidioidomycosis; Dermatomycoses; Drug Administration Schedule; Female; HIV Infections; Humans; Joint Diseases; Lung Diseases, Fungal; Male; Middle Aged; Treatment Outcome; Triazoles

1994

Other Studies

353 other study(ies) available for triazoles and HIV Infections

ArticleYear
Total and Unbound Doravirine Concentrations and Viral Suppression in CSF.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022, 05-30, Volume: 74, Issue:10

    Topics: HIV Infections; HIV-1; Humans; Pyridones; Triazoles; Virus Replication

2022
Structure-based identification of novel scaffolds as potential HIV-1 entry inhibitors involving CCR5.
    Journal of biomolecular structure & dynamics, 2022, Volume: 40, Issue:23

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Receptors, CCR5; Receptors, Chemokine; Triazoles

2022
Impact of HIV-1 Resistance-Associated Mutations on Susceptibility to Doravirine: Analysis of Real-World Clinical Isolates.
    Antimicrobial agents and chemotherapy, 2021, 11-17, Volume: 65, Issue:12

    Topics: Anti-HIV Agents; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Pyridones; Reverse Transcriptase Inhibitors; Triazoles

2021
Altered Env conformational dynamics as a mechanism of resistance to peptide-triazole HIV-1 inactivators.
    Retrovirology, 2021, 10-09, Volume: 18, Issue:1

    Topics: Anti-HIV Agents; Binding Sites; Drug Resistance, Viral; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Molecular Docking Simulation; Mutation; Peptides; Protein Conformation; Triazoles; Virus Internalization

2021
The Novel PKC Activator 10-Methyl-Aplog-1 Combined with JQ1 Induced Strong and Synergistic HIV Reactivation with Tolerable Global T Cell Activation.
    Viruses, 2021, 10-09, Volume: 13, Issue:10

    Topics: Anti-HIV Agents; Azepines; Bryostatins; CD4-Positive T-Lymphocytes; Cell Line; HIV Infections; HIV-1; Humans; Lymphocyte Activation; Phorbol Esters; Signal Transduction; Triazoles; Virus Latency

2021
Tenofovir plasma trough concentrations in people with HIV treated with doravirine versus other antiretroviral regimens.
    AIDS (London, England), 2021, 12-01, Volume: 35, Issue:15

    Topics: Anti-HIV Agents; HIV Infections; Humans; Pyridones; Tenofovir; Triazoles

2021
Real life use of dolutegravir doravirine dual regimen in experienced elderly PLWH with multiple comorbidities and on polypharmacy: A retrospective analysis.
    Medicine, 2021, Dec-30, Volume: 100, Issue:52

    Topics: Aged; Aged, 80 and over; Anti-HIV Agents; Female; Heterocyclic Compounds, 3-Ring; HIV Infections; Humans; Infant; Male; Middle Aged; Oxazines; Piperazines; Polypharmacy; Pyridones; Retrospective Studies; Treatment Outcome; Triazoles; Viral Load

2021
Prevalence of doravirine cross-resistance in HIV-infected adults who failed first-line ART in China, 2014-18.
    The Journal of antimicrobial chemotherapy, 2022, 03-31, Volume: 77, Issue:4

    Topics: Adult; Anti-HIV Agents; China; Drug Resistance, Viral; Genotype; HIV Infections; HIV-1; Humans; Mutation; Prevalence; Pyridones; Reverse Transcriptase Inhibitors; Triazoles

2022
Low prevalence of doravirine-associated resistance mutations among polish human immunodeficiency-1 (HIV-1)-infected patients.
    Antiviral therapy, 2021, Volume: 26, Issue:3-5

    Topics: Agammaglobulinemia; Anti-HIV Agents; Drug Resistance, Viral; Genetic Diseases, X-Linked; HIV Infections; HIV-1; Humans; Mutation; Nevirapine; Poland; Prevalence; Pyridones; Reverse Transcriptase Inhibitors; Triazoles

2021
Doravirine/tenofovir disoproxyl fumarate/lamivudine-induced alopecia: A case report.
    International journal of STD & AIDS, 2022, Volume: 33, Issue:7

    Topics: Alopecia; Anti-HIV Agents; Anti-Retroviral Agents; Emtricitabine; Fumarates; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Pyridones; Tenofovir; Triazoles; Viral Load

2022
Real-life use of Doravirine in treatment-experienced people living with HIV: A multicenter Italian study.
    Medicine, 2022, Jul-29, Volume: 101, Issue:30

    Topics: Anti-HIV Agents; DNA-Directed RNA Polymerases; Female; HIV Infections; Humans; Integrase Inhibitors; Male; Middle Aged; Pyridones; Retrospective Studies; Reverse Transcriptase Inhibitors; Triazoles

2022
Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability.
    Journal of medicinal chemistry, 2022, 12-22, Volume: 65, Issue:24

    Topics: Animals; Anti-HIV Agents; Biological Availability; CCR5 Receptor Antagonists; Cyclohexanes; HIV Infections; HIV-1; Maraviroc; Rats; Rats, Sprague-Dawley; Receptors, CCR5; Triazoles; Tropanes

2022
Rational Design of Doravirine: From Bench to Patients.
    ACS infectious diseases, 2020, 01-10, Volume: 6, Issue:1

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Design; Drug Interactions; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Pyridones; Reverse Transcriptase Inhibitors; Translational Research, Biomedical; Triazoles

2020
Prevalence of doravirine-associated resistance mutations in HIV-1-infected antiretroviral-experienced patients from two large databases in France and Italy.
    The Journal of antimicrobial chemotherapy, 2020, 04-01, Volume: 75, Issue:4

    Topics: Anti-HIV Agents; Drug Resistance, Viral; France; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Italy; Mutation; Prevalence; Pyridones; Reverse Transcriptase Inhibitors; Triazoles

2020
The algorithm used for the interpretation of doravirine transmitted drug resistance strongly influences clinical practice and guideline recommendations.
    The Journal of antimicrobial chemotherapy, 2020, 05-01, Volume: 75, Issue:5

    Topics: Algorithms; Anti-HIV Agents; Drug Resistance, Viral; Genotype; HIV Infections; Humans; Mutation; Prevalence; Pyridones; Spain; Triazoles

2020
Development and validation of a multiplex UHPLC-MS/MS assay with stable isotopic internal standards for the monitoring of the plasma concentrations of the antiretroviral drugs bictegravir, cabotegravir, doravirine, and rilpivirine in people living with HI
    Journal of mass spectrometry : JMS, 2020, Volume: 55, Issue:6

    Topics: Amides; Anti-Retroviral Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Heterocyclic Compounds, 3-Ring; Heterocyclic Compounds, 4 or More Rings; HIV Infections; Humans; Limit of Detection; Linear Models; Piperazines; Pyridones; Reference Standards; Reproducibility of Results; Rilpivirine; Tandem Mass Spectrometry; Triazoles

2020
Composition and Orientation of the Core Region of Novel HIV-1 Entry Inhibitors Influences Metabolic Stability.
    Molecules (Basel, Switzerland), 2020, Mar-21, Volume: 25, Issue:6

    Topics: Anti-HIV Agents; Azabicyclo Compounds; Azetidines; Chromatography, Liquid; HEK293 Cells; HIV Core Protein p24; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Microsomes, Liver; Organophosphates; Piperazines; Protein Binding; Pyrrolidines; Tandem Mass Spectrometry; Triazoles

2020
HIV-1 infection and latency-reversing agents bryostatin-1 and JQ1 disrupt amyloid beta homeostasis in human astrocytes.
    Glia, 2020, Volume: 68, Issue:11

    Topics: Amyloid beta-Peptides; Astrocytes; Azepines; Bryostatins; HIV Infections; HIV-1; Homeostasis; Humans; Triazoles; Virus Activation; Virus Latency

2020
Application of Structure-based Methods to Analyze Resistance Mutations for Chemically Diverse Non-Nucleoside Reverse Transcriptase Inhibitors.
    Current HIV research, 2020, Volume: 18, Issue:4

    Topics: Allosteric Site; Anti-HIV Agents; Binding Sites; Drug Resistance, Viral; Enzyme Assays; Gene Expression; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Pyridines; Pyridones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thermodynamics; Triazoles; Urea

2020
Filgotinib suppresses HIV-1-driven gene transcription by inhibiting HIV-1 splicing and T cell activation.
    The Journal of clinical investigation, 2020, 09-01, Volume: 130, Issue:9

    Topics: CD4-Positive T-Lymphocytes; HIV Infections; HIV-1; Humans; Jurkat Cells; Lymphocyte Activation; Pyridines; RNA Splicing; Transcription, Genetic; Triazoles

2020
Doravirine Use in Treatment-Experienced HIV-Positive Patients.
    The Annals of pharmacotherapy, 2021, Volume: 55, Issue:1

    Topics: Anti-HIV Agents; HIV Infections; Humans; Pyridones; Reverse Transcriptase Inhibitors; Triazoles

2021
Structure-based non-nucleoside inhibitor design: Developing inhibitors that are effective against resistant mutants.
    Chemical biology & drug design, 2021, Volume: 97, Issue:1

    Topics: Anti-HIV Agents; Binding Sites; Drug Design; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Dynamics Simulation; Mutation; Pyridones; Pyrimidines; Rilpivirine; Triazoles

2021
Clearance of HIV infection by selective elimination of host cells capable of producing HIV.
    Nature communications, 2020, 08-13, Volume: 11, Issue:1

    Topics: Animals; Antigens, CD34; Apoptosis; Autophagy; Azepines; CD4-Positive T-Lymphocytes; HIV Infections; HIV-1; Humans; Mice; Organophosphates; Piperazines; Pyridines; Pyrimidinones; RNA, Viral; T-Lymphocytes; Triazoles

2020
Antigenicity and Immunogenicity of HIV-1 Envelope Trimers Complexed to a Small-Molecule Viral Entry Inhibitor.
    Journal of virology, 2020, 10-14, Volume: 94, Issue:21

    Topics: Animals; Anti-HIV Agents; Antibodies, Neutralizing; Antibodies, Viral; CD4 Antigens; CD4-Positive T-Lymphocytes; CHO Cells; Cricetulus; env Gene Products, Human Immunodeficiency Virus; Glycosylation; HEK293 Cells; HIV Infections; HIV-1; Humans; Immunoconjugates; Macaca mulatta; Piperazines; Protein Multimerization; Rabbits; Recombinant Proteins; Triazoles

2020
Population Pharmacokinetic and Pharmacodynamic Analysis To Evaluate a Switch to Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate in People Living with HIV-1.
    Antimicrobial agents and chemotherapy, 2020, 10-20, Volume: 64, Issue:11

    Topics: Anti-HIV Agents; Emtricitabine; Fumarates; HIV Infections; HIV-1; Humans; Lamivudine; Pyridones; Tenofovir; Triazoles

2020
2019 update of the European AIDS Clinical Society Guidelines for treatment of people living with HIV version 10.0.
    HIV medicine, 2020, Volume: 21, Issue:10

    Topics: Age Factors; Anti-Retroviral Agents; Comorbidity; Drug Interactions; Drug Therapy, Combination; Heterocyclic Compounds, 3-Ring; HIV Infections; HIV Integrase Inhibitors; Humans; Lamivudine; Oxazines; Piperazines; Pyridones; Treatment Outcome; Triazoles

2020
In vitro cross-resistance to doravirine in a panel of HIV-1 clones harbouring multiple NNRTI resistance mutations.
    The Journal of antimicrobial chemotherapy, 2021, 01-01, Volume: 76, Issue:1

    Topics: Anti-HIV Agents; Clone Cells; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Nitriles; Pyridones; Pyrimidines; Reverse Transcriptase Inhibitors; Triazoles

2021
Changes in weight and BMI with first-line doravirine-based therapy.
    AIDS (London, England), 2021, 01-01, Volume: 35, Issue:1

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Mass Index; CD4 Lymphocyte Count; Darunavir; HIV Infections; Humans; Pyridones; Ritonavir; Treatment Outcome; Triazoles; Viral Load

2021
Successful treatment by doravirine with cobicistat-boosted darunavir for end-stage renal failure under chronic haemodialysis.
    The Journal of antimicrobial chemotherapy, 2021, 04-13, Volume: 76, Issue:5

    Topics: Anti-HIV Agents; Cobicistat; Darunavir; HIV Infections; HIV Protease Inhibitors; Humans; Kidney Failure, Chronic; Pyridones; Renal Dialysis; Triazoles

2021
Cell culture selections reveal favourable drug resistance profiles for doravirine and islatravir.
    The Journal of antimicrobial chemotherapy, 2021, 07-15, Volume: 76, Issue:8

    Topics: Anti-HIV Agents; Cell Culture Techniques; Deoxyadenosines; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Pyridones; Reverse Transcriptase Inhibitors; Triazoles

2021
Is there a role for doravirine in African HIV treatment programmes? A large observational resistance study in South Africa.
    Journal of the International AIDS Society, 2021, Volume: 24, Issue:5

    Topics: Anti-HIV Agents; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Mutation; Pyridones; Retrospective Studies; South Africa; Triazoles

2021
Real-Life Safety of Doravirine in Treatment-Experienced, Virologically Suppressed PLWHIV.
    Journal of acquired immune deficiency syndromes (1999), 2021, 09-01, Volume: 88, Issue:1

    Topics: Anti-HIV Agents; HIV Infections; Humans; Pyridones; Reverse Transcriptase Inhibitors; Triazoles

2021
Repurposing a Bacterial Immune System to Discover Antiviral Targets.
    The New England journal of medicine, 2017, 03-30, Volume: 376, Issue:13

    Topics: Antiviral Agents; Cell Line; Clustered Regularly Interspaced Short Palindromic Repeats; Cyclohexanes; Gene Knockout Techniques; HIV Infections; HIV-1; Humans; Immune System; Maraviroc; RNA, Viral; T-Lymphocytes; Triazoles; Viral Proteins; Virion; Virus Replication

2017
Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV.
    Immunity, 2017, 06-20, Volume: 46, Issue:6

    Topics: Animals; CCR5 Receptor Antagonists; Chemokine CCL5; Cloning, Molecular; Crystallography, X-Ray; Cyclohexanes; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Models, Molecular; Molecular Mimicry; Protein Binding; Protein Conformation; Receptors, CCR5; Sf9 Cells; Spodoptera; Structure-Activity Relationship; Triazoles; Virus Internalization

2017
Analysis of Clinical HIV-1 Strains with Resistance to Maraviroc Reveals Strain-Specific Resistance Mutations, Variable Degrees of Resistance, and Minimal Cross-Resistance to Other CCR5 Antagonists.
    AIDS research and human retroviruses, 2017, Volume: 33, Issue:12

    Topics: Adult; Anti-HIV Agents; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cell Line; Cyclohexanes; Drug Resistance, Viral; Female; HEK293 Cells; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Receptors, CCR5; Treatment Failure; Triazoles; Virus Internalization

2017
Penetration and antiviral efficacy of total and unbound maraviroc, raltegravir and rilpivirine in both female and male genital fluids from HIV-positive patients receiving regimens containing these antiretrovirals.
    The Journal of antimicrobial chemotherapy, 2017, Nov-01, Volume: 72, Issue:11

    Topics: Adult; Anti-HIV Agents; Body Fluids; Cervix Uteri; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Prospective Studies; Raltegravir Potassium; Rilpivirine; Semen; Triazoles; Vagina; Viral Load

2017
A New Quinoline BRD4 Inhibitor Targets a Distinct Latent HIV-1 Reservoir for Reactivation from Other "Shock" Drugs.
    Journal of virology, 2018, 05-15, Volume: 92, Issue:10

    Topics: Azepines; CD4-Positive T-Lymphocytes; Cell Cycle Proteins; Gene Expression Regulation, Viral; HEK293 Cells; HeLa Cells; Histone Deacetylase Inhibitors; HIV Infections; HIV-1; Humans; Jurkat Cells; Nuclear Proteins; Protein Domains; Proto-Oncogene Proteins c-myc; Proviruses; Quinolines; Transcription Factors; Triazoles; Viral Load; Virus Activation; Virus Integration; Virus Latency

2018
Induction of autophagy by PI3K/MTOR and PI3K/MTOR/BRD4 inhibitors suppresses HIV-1 replication.
    The Journal of biological chemistry, 2018, 04-20, Volume: 293, Issue:16

    Topics: Anti-HIV Agents; Autophagy; Azepines; Cell Cycle Proteins; Cells, Cultured; HIV Infections; HIV-1; Humans; Imidazoles; Macrophages; Nuclear Proteins; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinolines; Signal Transduction; TOR Serine-Threonine Kinases; Transcription Factors; Triazoles; Virus Replication

2018
Unique Phenotypic Characteristics of Recently Transmitted HIV-1 Subtype C Envelope Glycoprotein gp120: Use of CXCR6 Coreceptor by Transmitted Founder Viruses.
    Journal of virology, 2018, 05-01, Volume: 92, Issue:9

    Topics: Adult; Anti-HIV Agents; Antibodies, Monoclonal; Antibodies, Neutralizing; Antibodies, Viral; CCR5 Receptor Antagonists; Cell Line; Cyclohexanes; HEK293 Cells; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Infant; Maraviroc; Receptors, CXCR6; Triazoles; Virus Replication

2018
Targeting the entrance channel of NNIBP: Discovery of diarylnicotinamide 1,4-disubstituted 1,2,3-triazoles as novel HIV-1 NNRTIs with high potency against wild-type and E138K mutant virus.
    European journal of medicinal chemistry, 2018, May-10, Volume: 151

    Topics: Anti-HIV Agents; Drug Design; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Niacinamide; Point Mutation; Structure-Activity Relationship; Triazoles

2018
HIV latency reversing agents act through Tat post translational modifications.
    Retrovirology, 2018, 05-11, Volume: 15, Issue:1

    Topics: Amino Acid Substitution; Anti-HIV Agents; Azepines; Cell Cycle Proteins; Gene Expression Regulation, Viral; Histone Deacetylase Inhibitors; HIV Infections; HIV-1; Humans; Mutation; Nuclear Proteins; Protein Processing, Post-Translational; RNA Splicing; tat Gene Products, Human Immunodeficiency Virus; Transcription Factors; Transcription, Genetic; Triazoles; Virus Activation; Virus Latency; Virus Replication

2018
Procyanidin trimer C1 reactivates latent HIV as a triple combination therapy with kansui and JQ1.
    PloS one, 2018, Volume: 13, Issue:11

    Topics: Anti-HIV Agents; Azepines; CD4-Positive T-Lymphocytes; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Flavonoids; HIV Infections; HIV-1; Humans; Jurkat Cells; Primary Cell Culture; Triazoles; Virus Latency

2018
Rare occurrence of doravirine resistance-associated mutations in HIV-1-infected treatment-naive patients.
    The Journal of antimicrobial chemotherapy, 2019, 03-01, Volume: 74, Issue:3

    Topics: Anti-HIV Agents; Drug Resistance, Viral; France; Gene Frequency; Greece; HIV Infections; HIV-1; Humans; Italy; Mutation, Missense; Prevalence; Pyridones; Triazoles

2019
Population Pharmacokinetics of Doravirine and Exposure-Response Analysis in Individuals with HIV-1.
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:4

    Topics: Adult; Aged; Anti-HIV Agents; Area Under Curve; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Pyridones; Reverse Transcriptase Inhibitors; Triazoles; Young Adult

2019
Prevalence of predicted resistance to doravirine in HIV-1-positive patients after exposure to non-nucleoside reverse transcriptase inhibitors.
    International journal of antimicrobial agents, 2019, Volume: 53, Issue:4

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Delavirdine; Drug Resistance, Viral; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Nevirapine; Nitriles; Pyridazines; Pyridones; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Treatment Outcome; Triazoles

2019
Immune reconstitution inflammatory syndrome in an HIV-infected patient with disseminated coccidioidomycosis.
    International journal of STD & AIDS, 2019, Volume: 30, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antifungal Agents; Antiretroviral Therapy, Highly Active; Coccidioidomycosis; Fluconazole; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Male; Prednisone; Treatment Outcome; Triazoles

2019
Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV.
    The Journal of clinical investigation, 2019, 07-22, Volume: 129, Issue:8

    Topics: Anti-Retroviral Agents; Azepines; Cell Cycle Proteins; Drug Design; Female; HIV Infections; HIV-1; Humans; Male; Protein Domains; Structure-Activity Relationship; tat Gene Products, Human Immunodeficiency Virus; Transcription Factors; Triazoles

2019
Use of cellular HIV DNA to predict virologic response to maraviroc: performance of population-based and deep sequencing.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2013, Volume: 56, Issue:11

    Topics: Cyclohexanes; DNA, Viral; Genotype; High-Throughput Nucleotide Sequencing; HIV; HIV Fusion Inhibitors; HIV Infections; Humans; Kaplan-Meier Estimate; Leukocytes, Mononuclear; Maraviroc; Treatment Outcome; Triazoles; Viral Tropism

2013
Use of G-protein-coupled and -uncoupled CCR5 receptors by CCR5 inhibitor-resistant and -sensitive human immunodeficiency virus type 1 variants.
    Journal of virology, 2013, Volume: 87, Issue:12

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; CD4-Positive T-Lymphocytes; Cell Line; Cyclohexanes; Drug Resistance, Viral; env Gene Products, Human Immunodeficiency Virus; GTP-Binding Proteins; HEK293 Cells; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Pertussis Toxin; Piperazines; Pyrimidines; Receptors, CCR5; Transfection; Triazoles

2013
A model of peptide triazole entry inhibitor binding to HIV-1 gp120 and the mechanism of bridging sheet disruption.
    Biochemistry, 2013, Apr-02, Volume: 52, Issue:13

    Topics: Anti-HIV Agents; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Conformation; Triazoles

2013
Sensitive cell-based assay for determination of human immunodeficiency virus type 1 coreceptor tropism.
    Journal of clinical microbiology, 2013, Volume: 51, Issue:5

    Topics: Anti-HIV Agents; Cell Fusion; Cell Line; Cyclohexanes; env Gene Products, Human Immunodeficiency Virus; Genome, Viral; Genotype; HEK293 Cells; HIV Infections; HIV-1; Humans; Maraviroc; Pilot Projects; Receptors, CCR5; Receptors, CXCR4; Receptors, HIV; RNA, Viral; Saccharomyces cerevisiae Proteins; Sensitivity and Specificity; Triazoles; Viral Tropism

2013
Pharmacokinetics of maraviroc administered at 150 mg once daily in association with lopinavir/ritonavir in HIV-positive treatment-naive patients.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:7

    Topics: Adult; Anti-HIV Agents; Cyclohexanes; Drug Therapy, Combination; HIV Infections; Humans; Lopinavir; Male; Maraviroc; Plasma; Ritonavir; Time Factors; Triazoles

2013
Multifaceted mechanisms of HIV inhibition and resistance to CCR5 inhibitors PSC-RANTES and Maraviroc.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:6

    Topics: Animals; Anti-HIV Agents; CCR5 Receptor Antagonists; Cell Line; Chemokine CCL5; Cyclohexanes; Down-Regulation; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Macaca; Maraviroc; Microbial Sensitivity Tests; Receptors, CCR5; Triazoles; Virus Internalization; Virus Replication

2013
Transplacental passage of etravirine and maraviroc in a multidrug-experienced HIV-infected woman failing on darunavir-based HAART in late pregnancy.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:8

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cyclohexanes; Darunavir; Female; HIV Infections; Humans; Infant; Infant, Newborn; Maraviroc; Nitriles; Pregnancy; Pregnancy Complications, Infectious; Pyridazines; Pyrimidines; RNA, Viral; Sulfonamides; Treatment Failure; Triazoles; Viral Load

2013
Results of external quality assessment for proviral DNA testing of HIV tropism in the Maraviroc Switch collaborative study.
    Journal of clinical microbiology, 2013, Volume: 51, Issue:7

    Topics: Anti-HIV Agents; Clinical Laboratory Techniques; Cyclohexanes; DNA, Viral; HIV Infections; HIV-1; Humans; Laboratory Proficiency Testing; Maraviroc; Proviruses; Triazoles; Viral Tropism

2013
Prevalence of R5 strains in multi-treated HIV subjects and impact of new regimens including maraviroc in a selected group of patients with CCR5-tropic HIV-1 infection.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2013, Volume: 17, Issue:10

    Topics: Adult; Aged; CCR5 Receptor Antagonists; Cyclohexanes; Drug Resistance, Viral; Drug Substitution; Female; Follow-Up Studies; Genotype; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Prevalence; Receptors, CCR5; Sequence Analysis, DNA; Treatment Outcome; Triazoles; Viral Load; Viral Tropism; Virus Replication; Young Adult

2013
A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations.
    Retrovirology, 2013, Apr-20, Volume: 10

    Topics: Anti-HIV Agents; Cyclohexanes; Genetic Variation; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Maraviroc; Molecular Sequence Data; Mutation, Missense; Sequence Analysis, DNA; Treatment Failure; Triazoles; Virus Internalization

2013
Profile of HIV type 1 coreceptor tropism among Kenyan patients from 2009 to 2010.
    AIDS research and human retroviruses, 2013, Volume: 29, Issue:8

    Topics: Adolescent; Adult; Aged; CCR5 Receptor Antagonists; Child; Child, Preschool; Cyclohexanes; Female; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Kenya; Male; Maraviroc; Middle Aged; Molecular Sequence Data; Receptors, CCR5; Receptors, CXCR4; Sequence Analysis, DNA; Triazoles; Viral Tropism; Young Adult

2013
Oral administration of the CCR5 inhibitor, maraviroc, blocks HIV ex vivo infection of Langerhans cells within the epithelium.
    The Journal of investigative dermatology, 2013, Volume: 133, Issue:12

    Topics: Administration, Oral; Adult; CCR5 Receptor Antagonists; Chromatography, Liquid; Coculture Techniques; Cyclohexanes; Drug Administration Schedule; Epithelium; HIV Fusion Inhibitors; HIV Infections; Humans; Langerhans Cells; Male; Maraviroc; Mass Spectrometry; Receptors, CCR5; Time Factors; Triazoles; Young Adult

2013
Maraviroc treatment in non-R5-HIV-1-infected patients results in the selection of extreme CXCR4-using variants with limited effect on the total viral setpoint.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:9

    Topics: Anti-HIV Agents; Cohort Studies; Cyclohexanes; High-Throughput Nucleotide Sequencing; HIV Infections; HIV-1; Humans; Longitudinal Studies; Maraviroc; Receptors, CCR5; Receptors, CXCR4; Receptors, HIV; Selection, Genetic; Triazoles; Viral Tropism

2013
Identifying chemicals with potential therapy of HIV based on protein-protein and protein-chemical interaction network.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: 1-Deoxynojirimycin; Algorithms; Anti-HIV Agents; CCR5 Receptor Antagonists; Computer Simulation; Cyclohexanes; Databases, Chemical; Didanosine; Drug Design; Drug Discovery; HIV Infections; HIV-1; Host-Pathogen Interactions; Humans; Maraviroc; Models, Molecular; Protein Interaction Mapping; Protein Interaction Maps; Receptors, CCR5; Triazoles

2013
Primary resistance of CCR5-tropic HIV-1 to maraviroc cannot be predicted by the V3 sequence.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:11

    Topics: Anti-HIV Agents; Cyclohexanes; Drug Resistance, Viral; France; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Inhibitory Concentration 50; Maraviroc; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation, Missense; Sequence Analysis, DNA; Triazoles

2013
Virologic response, early HIV-1 decay, and maraviroc pharmacokinetics with the nucleos(t)ide-free regimen of maraviroc plus darunavir/ritonavir in a pilot study.
    Journal of acquired immune deficiency syndromes (1999), 2013, Oct-01, Volume: 64, Issue:2

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cyclohexanes; Darunavir; Drug Therapy, Combination; Female; HIV Fusion Inhibitors; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Maraviroc; Pilot Projects; Ritonavir; RNA Stability; RNA, Viral; Sulfonamides; Treatment Outcome; Triazoles; Viral Load

2013
Analysis of primary resistance mutations to HIV-1 entry inhibitors in therapy naive subtype C HIV-1 infected mother-infant pairs from Zambia.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2013, Volume: 58, Issue:1

    Topics: Adult; Amino Acid Sequence; Cloning, Molecular; Cyclohexanes; Drug Resistance, Viral; env Gene Products, Human Immunodeficiency Virus; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Maraviroc; Molecular Sequence Data; Mutation, Missense; Piperazines; Pregnancy; Pyrimidines; Sequence Analysis, DNA; Triazoles; Young Adult; Zambia

2013
[Ophthalmological alterations at the initial diagnosis of HIV infection].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2014, Volume: 111, Issue:7

    Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; Cyclohexanes; Deoxycytidine; Drug Therapy, Combination; Early Diagnosis; Emtricitabine; Eye Infections, Viral; HIV Infections; Humans; Lopinavir; Male; Maraviroc; Organophosphonates; Retinal Diseases; Syndrome; Tenofovir; Treatment Outcome; Triazoles; Zidovudine

2014
Dissimilarities in the metabolism of antiretroviral drugs used in HIV pre-exposure prophylaxis in colon and vagina tissues.
    Biochemical pharmacology, 2013, Oct-01, Volume: 86, Issue:7

    Topics: Adult; Anti-HIV Agents; Chemoprevention; Colon; Cyclohexanes; Cytochrome P-450 Enzyme System; Female; Glucuronosyltransferase; HIV Infections; Humans; Isoenzymes; Male; Maraviroc; Mucous Membrane; Organ Specificity; Pyrimidines; Triazoles; Vagina; Young Adult

2013
Virological and immunological response to antiretroviral regimens containing maraviroc in HIV type 1-infected patients in clinical practice: role of different tropism testing results and of concomitant treatments.
    AIDS research and human retroviruses, 2014, Volume: 30, Issue:1

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Enfuvirtide; Female; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Peptide Fragments; Retrospective Studies; RNA, Viral; Survival; Triazoles; Viral Load; Viral Tropism

2014
A reduced grade of liver fibro-steatosis after raltegravir, maraviroc and fosamprenavir in an HIV/HCV co-infected patient with chronic hepatitis, cardiomyopathy, intolerance to nelfinavir and a marked increase of serum creatine phosphokinase levels probab
    The West Indian medical journal, 2012, Volume: 61, Issue:9

    Topics: Adult; Carbamates; Cardiomyopathies; Chemical and Drug Induced Liver Injury; Creatine Kinase; Cyclohexanes; Drug Substitution; Drug Therapy, Combination; Fatty Liver; Furans; Hepatitis C, Chronic; HIV Fusion Inhibitors; HIV Infections; HIV Integrase Inhibitors; HIV Protease Inhibitors; Humans; Liver Cirrhosis; Male; Maraviroc; Organophosphates; Pyrrolidinones; Raltegravir Potassium; Sulfonamides; Triazoles

2012
Maraviroc-induced decrease in circulating bacterial products is not linked to an increase in immune activation in HIV-infected individuals.
    Blood, 2013, Sep-26, Volume: 122, Issue:13

    Topics: CD4-Positive T-Lymphocytes; Cyclohexanes; Female; Graft vs Host Disease; HIV Infections; HIV-1; Humans; Male; Triazoles; Viral Load

2013
Response: Maraviroc intensification and microbial translocation.
    Blood, 2013, Sep-26, Volume: 122, Issue:13

    Topics: CD4-Positive T-Lymphocytes; Cyclohexanes; Female; Graft vs Host Disease; HIV Infections; HIV-1; Humans; Male; Triazoles; Viral Load

2013
Genotypic correlates of susceptibility to HIV-1 attachment inhibitor BMS-626529, the active agent of the prodrug BMS-663068.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:3

    Topics: Amino Acid Substitution; Anti-HIV Agents; Drug Resistance, Viral; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Molecular Sequence Data; Organophosphates; Piperazines; Prodrugs; Reverse Genetics; Sequence Analysis, DNA; Triazoles

2014
HIV-1 coreceptor tropism in India: increasing proportion of X4-tropism in subtype C strains over two decades.
    Journal of acquired immune deficiency syndromes (1999), 2014, Apr-01, Volume: 65, Issue:4

    Topics: Adolescent; Adult; Anti-HIV Agents; Child; Child, Preschool; Cyclohexanes; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; India; Male; Maraviroc; Middle Aged; Polymorphism, Genetic; Receptors, HIV; Triazoles; Viral Tropism; Young Adult

2014
Oral CCR5 inhibitors to prevent HIV transmission: the new "morning-before pill"?
    The Journal of investigative dermatology, 2013, Volume: 133, Issue:12

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Epithelium; HIV Fusion Inhibitors; HIV Infections; Humans; Langerhans Cells; Male; Maraviroc; Receptors, CCR5; Triazoles

2013
In vitro characterization of MK-1439, a novel HIV-1 nonnucleoside reverse transcriptase inhibitor.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:3

    Topics: Anti-HIV Agents; Drug Synergism; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Macrophages; Monocytes; Pyridones; Triazoles; Virus Replication

2014
Viral rebound after switch to maraviroc/raltegravir dual therapy in highly experienced and virologically suppressed patients with HIV-1 infection.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:5

    Topics: Cyclohexanes; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Mutation, Missense; Pyrrolidinones; Raltegravir Potassium; Treatment Failure; Triazoles; Viral Load

2014
Innate immunity cell activation in virologically suppressed HIV-infected maraviroc-treated patients.
    AIDS (London, England), 2014, Apr-24, Volume: 28, Issue:7

    Topics: Adult; Anti-Retroviral Agents; Antigens, CD; Biomarkers; Case-Control Studies; Cross-Sectional Studies; Cyclohexanes; Female; HIV Infections; HLA Antigens; Humans; Killer Cells, Natural; Male; Maraviroc; Middle Aged; Monocytes; Treatment Outcome; Triazoles

2014
A validated HPLC-MS method for quantification of the CCR5 inhibitor maraviroc in HIV+ human plasma.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 94

    Topics: Calibration; CCR5 Receptor Antagonists; Chromatography, High Pressure Liquid; Cyclohexanes; HIV Infections; Humans; Limit of Detection; Maraviroc; Mass Spectrometry; Receptors, CCR5; Reference Standards; Sensitivity and Specificity; Triazoles

2014
Efficacy and safety of once-daily maraviroc plus ritonavir-boosted darunavir in pretreated HIV-infected patients in a real-life setting.
    HIV medicine, 2014, Volume: 15, Issue:7

    Topics: Adult; Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; Darunavir; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Fusion Inhibitors; HIV Infections; HIV Protease Inhibitors; Humans; Male; Maraviroc; Middle Aged; Retrospective Studies; Ritonavir; RNA, Viral; Sulfonamides; Triazoles

2014
Modified silicone elastomer vaginal gels for sustained release of antiretroviral HIV microbicides.
    Journal of pharmaceutical sciences, 2014, Volume: 103, Issue:5

    Topics: Administration, Intravaginal; Anti-Infective Agents, Local; Anti-Retroviral Agents; Cellulose; Cyclohexanes; Delayed-Action Preparations; Female; Gels; HIV Infections; HIV-1; Humans; Hydrophobic and Hydrophilic Interactions; Maraviroc; Silicone Elastomers; Triazoles; Vagina; Vaginal Creams, Foams, and Jellies

2014
Maraviroc reduces the regulatory T-cell frequency in antiretroviral-naive HIV-infected subjects.
    The Journal of infectious diseases, 2014, Sep-15, Volume: 210, Issue:6

    Topics: Adult; CD4 Lymphocyte Count; Cyclohexanes; Dose-Response Relationship, Drug; Female; Flow Cytometry; HIV Fusion Inhibitors; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Receptors, CCR5; Retrospective Studies; T-Lymphocytes, Regulatory; Triazoles

2014
New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo.
    Nature medicine, 2014, Volume: 20, Issue:4

    Topics: Anti-HIV Agents; Azepines; Bryostatins; CD4-Positive T-Lymphocytes; Cell Cycle Proteins; Depsipeptides; Disulfiram; Histone Deacetylase Inhibitors; HIV Infections; HIV-1; Humans; Hydroxamic Acids; Indoles; Ionomycin; Lymphocyte Activation; Nuclear Proteins; Panobinostat; Tetradecanoylphorbol Acetate; Transcription Factors; Triazoles; Virus Latency; Vorinostat

2014
Reactivation of hepatitis B virus infection associated with maraviroc use in an HIV-infected patient.
    AIDS (London, England), 2014, Apr-24, Volume: 28, Issue:7

    Topics: Aged; Anti-HIV Agents; Cyclohexanes; Hepatitis B; Hepatitis B virus; HIV Infections; Humans; Male; Maraviroc; Triazoles; Virus Activation

2014
Potential anti-inflammatory effects of maraviroc in HIV-positive patients: a pilot study of inflammation, endothelial dysfunction, and coagulation markers.
    Scandinavian journal of infectious diseases, 2014, Volume: 46, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Biomarkers; Case-Control Studies; CCR5 Receptor Antagonists; Cyclohexanes; Cytokines; Female; HIV Fusion Inhibitors; HIV Infections; Humans; Inflammation; Male; Maraviroc; Middle Aged; Pilot Projects; Thrombophilia; Triazoles

2014
Maraviroc intensification in patients with suppressed HIV viremia has limited effects on CD4+ T cell recovery and gene expression.
    Antiviral research, 2014, Volume: 107

    Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cell Proliferation; Cyclohexanes; Female; Gene Expression; Gene Expression Profiling; HIV Infections; Humans; Male; Maraviroc; Microarray Analysis; Middle Aged; Treatment Outcome; Triazoles; Tumor Necrosis Factor-alpha; Viremia

2014
HIV-2 viral tropism influences CD4+ T cell count regardless of viral load.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:8

    Topics: Adult; Anti-HIV Agents; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cyclohexanes; Female; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-2; Humans; Male; Maraviroc; Middle Aged; Peptide Fragments; RNA, Viral; Spain; Triazoles; Viral Load; Viral Tropism; Viremia

2014
Seminal pharmacokinetics and antiviral efficacy of once-daily maraviroc plus lopinavir/ritonavir in HIV-infected patients.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:9

    Topics: Adult; Anti-HIV Agents; Cyclohexanes; HIV Infections; Humans; Lopinavir; Male; Maraviroc; Middle Aged; Plasma; Ritonavir; Semen; Triazoles

2014
Extravirologic modulation of immune response by an NRTI-sparing antiretroviral regimen including darunavir and maraviroc.
    The new microbiologica, 2014, Volume: 37, Issue:2

    Topics: Anti-HIV Agents; Apoptosis; Cells, Cultured; Cyclohexanes; Darunavir; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Maraviroc; Neutrophils; Sulfonamides; Triazoles

2014
Exposure to entry inhibitors alters HIV infectiousness and sensitivity to broadly neutralizing monoclonal antibodies.
    Journal of acquired immune deficiency syndromes (1999), 2014, Sep-01, Volume: 67, Issue:1

    Topics: Antibodies, Monoclonal; Cell Line; Cyclohexanes; Drug Synergism; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Inhibitory Concentration 50; Maraviroc; Neutralization Tests; Regression Analysis; Triazoles; Virus Replication

2014
Electrospun solid dispersions of Maraviroc for rapid intravaginal preexposure prophylaxis of HIV.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8

    Topics: Administration, Intravaginal; Anti-HIV Agents; Anti-Infective Agents, Local; Cell Line; Cell Survival; Cyclohexanes; Electrochemical Techniques; Excipients; Female; HIV Infections; Humans; Kinetics; Maraviroc; Nanofibers; Polyethylene Glycols; Polysorbates; Povidone; Suspensions; Triazoles; Vaginal Creams, Foams, and Jellies; Wettability; Wetting Agents

2014
Switching safely: pharmacokinetics, efficacy and safety of switching efavirenz to maraviroc twice daily in patients on suppressive antiretroviral therapy.
    Antiviral therapy, 2015, Volume: 20, Issue:2

    Topics: Adult; Alkynes; Area Under Curve; Benzoxazines; Cyclohexanes; Cyclopropanes; Drug Administration Schedule; Drug Substitution; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Reverse Transcriptase Inhibitors; Treatment Outcome; Triazoles; Viral Load

2015
CCR5 as a treatment target in pulmonary arterial hypertension.
    Circulation, 2014, Sep-09, Volume: 130, Issue:11

    Topics: Animals; CCR5 Receptor Antagonists; Cell Proliferation; Cells, Cultured; Cyclohexanes; Disease Models, Animal; Familial Primary Pulmonary Hypertension; HIV Fusion Inhibitors; HIV Infections; Humans; Hypertension, Pulmonary; Hypoxia; Macaca mulatta; Macrophages; Male; Maraviroc; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Pulmonary Artery; Receptors, CCR5; Simian Acquired Immunodeficiency Syndrome; Triazoles

2014
HIV pre-exposure prophylaxis: mucosal tissue drug distribution of RT inhibitor Tenofovir and entry inhibitor Maraviroc in a humanized mouse model.
    Virology, 2014, Volume: 464-465

    Topics: Adenine; Animals; Anti-HIV Agents; Cyclohexanes; Disease Models, Animal; Female; HIV Infections; HIV-1; Humans; Maraviroc; Mice; Mucous Membrane; Organophosphonates; Pre-Exposure Prophylaxis; Reverse Transcriptase Inhibitors; Tenofovir; Triazoles; Virus Internalization

2014
The utility of genotypic tropism testing in clinical practice.
    International journal of STD & AIDS, 2015, Volume: 26, Issue:8

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; DNA, Viral; Drug Prescriptions; Female; Genotype; HIV Infections; HIV-1; Humans; London; Male; Maraviroc; Medical Audit; Practice Patterns, Physicians'; Retrospective Studies; RNA, Viral; Sequence Analysis, DNA; Triazoles; Viral Tropism

2015
HIV-2 X4 tropism is associated with lower CD4+ cell count in treatment-experienced patients.
    AIDS (London, England), 2014, Sep-10, Volume: 28, Issue:14

    Topics: CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Disease Progression; Drug Resistance, Viral; Genotype; HIV Infections; HIV-2; Humans; Maraviroc; Prevalence; Receptors, CCR5; Retrospective Studies; Triazoles; Viral Load; Viral Tropism

2014
Genetic barrier for attachment inhibitor BMS-626529 resistance in HIV-1 B and non-B subtypes.
    The Journal of antimicrobial chemotherapy, 2015, Volume: 70, Issue:1

    Topics: Amino Acid Substitution; Drug Resistance, Viral; Genotype; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Mutation, Missense; Piperazines; Polymorphism, Genetic; Triazoles

2015
Computational study on the interaction between CCR5 and HIV-1 entry inhibitor maraviroc: insight from accelerated molecular dynamics simulation and free energy calculation.
    Physical chemistry chemical physics : PCCP, 2014, Nov-28, Volume: 16, Issue:44

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; HIV Infections; HIV-1; Humans; Hydrogen Bonding; Maraviroc; Models, Molecular; Molecular Dynamics Simulation; Protein Conformation; Receptors, CCR5; Thermodynamics; Triazoles

2014
Treatment. Maraviroc dosing not effective in half of blacks.
    AIDS policy & law, 2014, Volume: 29, Issue:11

    Topics: Black People; Cyclohexanes; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Triazoles

2014
Antiretroviral-Experienced HIV-1-Infected Patients Treated with Maraviroc: Factors Associated with Virological Response.
    AIDS research and human retroviruses, 2015, Volume: 31, Issue:5

    Topics: Adult; Aged; Anti-Retroviral Agents; Cyclohexanes; Drug Therapy, Combination; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; RNA, Viral; Treatment Outcome; Triazoles; Viral Load; Young Adult

2015
Models for predicting effective HIV chemoprevention in women.
    Journal of acquired immune deficiency syndromes (1999), 2015, Apr-01, Volume: 68, Issue:4

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Cell Culture Techniques; Cell Survival; Chemoprevention; Chromatography, Liquid; Cyclohexanes; Disease Transmission, Infectious; Dose-Response Relationship, Drug; Female; HIV Infections; Humans; Maraviroc; Middle Aged; Organ Culture Techniques; Organophosphonates; Tandem Mass Spectrometry; Tenofovir; Triazoles; Vagina; Viral Load; Young Adult

2015
FT-IR and FT-Raman spectroscopic signatures, vibrational assignments, NBO, NLO analysis and molecular docking study of 2-{[5-(adamantan-1-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N,N-dimethylethanamine.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Apr-05, Volume: 140

    Topics: Adamantane; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Molecular Docking Simulation; Quantum Theory; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Triazoles

2015
Therapeutic use of CCR5 antagonists is supported by strong expression of CCR5 on CD8(+) T cells in progressive multifocal leukoencephalopathy-associated immune reconstitution inflammatory syndrome.
    Acta neuropathologica, 2015, Volume: 129, Issue:3

    Topics: Anti-Retroviral Agents; CCR5 Receptor Antagonists; CD8-Positive T-Lymphocytes; Cyclohexanes; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Leukoencephalopathy, Progressive Multifocal; Maraviroc; Microscopy, Confocal; Receptors, CCR5; Triazoles

2015
Antiretroviral blood levels in HIV/HCV-coinfected patients with cirrhosis after liver transplant: a report of three cases.
    Transplant infectious disease : an official journal of the Transplantation Society, 2015, Volume: 17, Issue:1

    Topics: Anti-Retroviral Agents; Coinfection; Cyclohexanes; Darunavir; Drug Monitoring; Female; Hepatitis C; HIV Infections; Humans; Liver Cirrhosis; Liver Transplantation; Male; Maraviroc; Middle Aged; Nitriles; Pyridazines; Pyrimidines; Triazoles

2015
Virological failure of patients on maraviroc-based antiretroviral therapy.
    The Journal of antimicrobial chemotherapy, 2015, Volume: 70, Issue:6

    Topics: Adult; Aged; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Cyclohexanes; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Retrospective Studies; Treatment Failure; Triazoles; Viral Load; Viral Tropism

2015
Reliable genotypic tropism tests for the major HIV-1 subtypes.
    Scientific reports, 2015, Feb-25, Volume: 5

    Topics: Algorithms; Amino Acid Sequence; CCR5 Receptor Antagonists; Computational Biology; Cyclohexanes; Genotype; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Maraviroc; Mutation; Peptide Fragments; Phenotype; Receptors, CCR5; Triazoles; Viral Tropism

2015
Switch to maraviroc/raltegravir dual therapy leads to an unfavorable immune profile with low-level HIV viremia.
    AIDS (London, England), 2015, Apr-24, Volume: 29, Issue:7

    Topics: Anti-HIV Agents; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclohexanes; Female; HIV Infections; Humans; Lymphocyte Activation; Male; Maraviroc; Middle Aged; Monocytes; Raltegravir Potassium; RNA, Viral; Treatment Outcome; Triazoles; Viral Load; Viremia

2015
Highly efficient synthesis of HIV NNRTI doravirine.
    Organic letters, 2015, Mar-20, Volume: 17, Issue:6

    Topics: Aldehydes; HIV Infections; HIV Reverse Transcriptase; Molecular Structure; Pyridones; Reverse Transcriptase Inhibitors; Triazoles

2015
A prospective evaluation of maraviroc administration in patients with advanced HIV disease and multiple comorbidities: focus on efficacy and tolerability issues.
    Le infezioni in medicina, 2015, Volume: 23, Issue:1

    Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Comorbidity; Cyclohexanes; Female; Follow-Up Studies; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Prospective Studies; Treatment Outcome; Triazoles; Viral Load

2015
Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations.
    The Journal of clinical investigation, 2015, Volume: 125, Issue:5

    Topics: Adult; Anti-HIV Agents; Azepines; Bryostatins; CD4-Positive T-Lymphocytes; Cells, Cultured; Disulfiram; Drug Evaluation, Preclinical; Drug Synergism; Female; Histone Deacetylase Inhibitors; HIV Infections; HIV-1; Humans; Lymphocyte Activation; Lymphokines; Male; Middle Aged; Phorbol Esters; Protein Kinase C; RNA, Messenger; RNA, Viral; Transcription, Genetic; Triazoles; Virion; Virus Latency

2015
Triple combination of carbosilane dendrimers, tenofovir and maraviroc as potential microbicide to prevent HIV-1 sexual transmission.
    Nanomedicine (London, England), 2015, Volume: 10, Issue:6

    Topics: Adenine; Animals; Anti-HIV Agents; Anti-Infective Agents; Antiviral Agents; Cell Survival; Cyclohexanes; Dendrimers; Drug Combinations; Female; HIV Infections; HIV-1; Humans; Maraviroc; Mice; Mice, Inbred BALB C; Mucous Membrane; Organophosphonates; Silanes; Software; Tenofovir; Triazoles; Vagina

2015
Characterization of HIV-1 entry inhibitors with broad activity against R5 and X4 viral strains.
    Journal of translational medicine, 2015, Apr-02, Volume: 13

    Topics: 3T3 Cells; Animals; Antiviral Agents; Benzylamines; Cell Death; Cell Line; Cyclams; Cyclohexanes; Flow Cytometry; Heterocyclic Compounds; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Membrane Fusion; Mice; Receptors, CCR5; Receptors, CXCR4; Triazoles; Virus Internalization; Virus Replication

2015
Preclinical discovery and development of maraviroc for the treatment of HIV.
    Expert opinion on drug discovery, 2015, Volume: 10, Issue:6

    Topics: Adult; Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Maraviroc; Triazoles

2015
Development of maraviroc, a CCR5 antagonist for treatment of HIV, using a novel tropism assay.
    Annals of the New York Academy of Sciences, 2015, Volume: 1346, Issue:1

    Topics: Anti-HIV Agents; Biological Assay; Clinical Trials as Topic; Cyclohexanes; Drug Design; Drug Evaluation, Preclinical; HIV Infections; HIV-1; Humans; Maraviroc; Receptors, CCR5; Triazoles; Viral Tropism

2015
Ineffective central nervous system HIV suppression of once-a-day maraviroc and ritonavir-boosted darunavir dual therapy: four case reports.
    International journal of STD & AIDS, 2016, Volume: 27, Issue:4

    Topics: Adult; Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; Darunavir; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Maraviroc; Middle Aged; Nervous System; Ritonavir; RNA, Viral; Treatment Outcome; Triazoles; Viral Load

2016
Parameters Influencing Baseline HIV-1 Genotypic Tropism Testing Related to Clinical Outcome in Patients on Maraviroc.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cyclohexanes; Female; Genes, Viral; Genetic Association Studies; Genotype; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Treatment Outcome; Triazoles; Viral Tropism; Young Adult

2015
Safety, efficacy and indications of prescription of maraviroc in clinical practice: Factors associated with clinical outcomes.
    Antiviral research, 2015, Volume: 120

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cyclohexanes; Female; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Retrospective Studies; RNA, Viral; Salvage Therapy; Treatment Outcome; Triazoles; Viral Load

2015
The efficacy and safety of maraviroc addition to a stable antiretroviral regimen in subjects with suppressed plasma HIV-RNA is not influenced by age.
    AIDS research and human retroviruses, 2015, Volume: 31, Issue:9

    Topics: Adult; Age Factors; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CCR5 Receptor Antagonists; Cyclohexanes; HIV; HIV Infections; Humans; Maraviroc; Middle Aged; Multivariate Analysis; Retrospective Studies; RNA, Viral; Treatment Outcome; Triazoles; Viral Load

2015
HIV-1 Coreceptor Usage Assessment by Ultra-Deep Pyrosequencing and Response to Maraviroc.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Adult; Algorithms; Antiretroviral Therapy, Highly Active; Area Under Curve; Cyclohexanes; Female; High-Throughput Nucleotide Sequencing; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Peptide Fragments; RNA, Viral; ROC Curve; Sequence Analysis, RNA; Software; Triazoles; Viral Tropism

2015
Pharmacodynamic Activity of Dapivirine and Maraviroc Single Entity and Combination Topical Gels for HIV-1 Prevention.
    Pharmaceutical research, 2015, Volume: 32, Issue:11

    Topics: Administration, Topical; Anti-HIV Agents; Cell Survival; Cervix Uteri; Colon; Cyclohexanes; Drug Combinations; Drug Liberation; Female; Gels; HIV Fusion Inhibitors; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Maraviroc; Mucous Membrane; Pyrimidines; Rectum; Rheology; Triazoles

2015
Maraviroc Clinical Test (MCT) as an alternative tool to decide CCR5-antagonists prescription in naïve HIV-infected patients.
    Antiviral research, 2015, Volume: 121

    Topics: Adult; Aged; Anti-HIV Agents; Cyclohexanes; Female; Genotype; Genotyping Techniques; HIV; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Retrospective Studies; RNA, Viral; Time Factors; Treatment Outcome; Triazoles; Viral Load; Viral Tropism; Young Adult

2015
Impact of the Maraviroc-Resistant Mutation M434I in the C4 Region of HIV-1 gp120 on Sensitivity to Antibody-Mediated Neutralization.
    Japanese journal of infectious diseases, 2016, May-20, Volume: 69, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Neutralizing; Antibodies, Viral; CD4-Positive T-Lymphocytes; Cell Line; Cyclohexanes; Drug Resistance, Viral; Gene Expression; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Immune Sera; Immunoglobulin G; Maraviroc; Mutation; Neutralization Tests; Receptors, CCR5; Triazoles

2016
Maraviroc modifies gut microbiota composition in a mouse model of obesity: a plausible therapeutic option to prevent metabolic disorders in HIV-infected patients.
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2015, Volume: 28, Issue:4

    Topics: Animals; Bacterial Translocation; Bacteroidetes; CCR5 Receptor Antagonists; Cecum; Cyclohexanes; Diet, High-Fat; Drug Evaluation, Preclinical; Firmicutes; HIV Fusion Inhibitors; HIV Infections; Humans; Insulin Resistance; Male; Maraviroc; Metabolic Diseases; Mice; Mice, Inbred C57BL; Microbiota; Non-alcoholic Fatty Liver Disease; Obesity; Proteobacteria; Random Allocation; Species Specificity; Triazoles; Weight Gain

2015
Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation.
    PLoS pathogens, 2015, Volume: 11, Issue:7

    Topics: Azepines; Diterpenes; HIV Infections; HIV-1; Humans; I-kappa B Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Positive Transcriptional Elongation Factor B; Signal Transduction; T-Lymphocytes; Triazoles; Virus Activation; Virus Latency

2015
Cenicriviroc, a Novel CCR5 (R5) and CCR2 Antagonist, Shows In Vitro Activity against R5 Tropic HIV-2 Clinical Isolates.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Cells, Cultured; Coculture Techniques; Cyclohexanes; HIV Infections; HIV-2; Humans; Imidazoles; Leukocytes, Mononuclear; Maraviroc; Phenotype; Phytohemagglutinins; Receptors, CCR2; Receptors, CCR5; Sulfoxides; Triazoles; Virus Replication

2015
Characterizing the Diverse Mutational Pathways Associated with R5-Tropic Maraviroc Resistance: HIV-1 That Uses the Drug-Bound CCR5 Coreceptor.
    Journal of virology, 2015, Volume: 89, Issue:22

    Topics: Amino Acid Sequence; Base Sequence; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; Drug Resistance, Viral; Glycosylation; HIV Envelope Protein gp120; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Molecular Sequence Data; Protein Structure, Tertiary; Receptors, CCR5; Receptors, CXCR4; Sequence Alignment; Sequence Analysis, RNA; Signal Transduction; Treatment Failure; Triazoles; Virus Internalization; Virus Replication

2015
Synergistic Inhibition of R5 HIV-1 by the Fusion Protein (FLSC) IgG1 Fc and Maraviroc in Primary Cells: Implications for Prevention and Treatment.
    Current HIV research, 2016, Volume: 14, Issue:1

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Cell Line; Cyclohexanes; Drug Synergism; Flow Cytometry; HIV Infections; HIV-1; Humans; Immunoglobulin G; Maraviroc; Receptors, CCR5; Receptors, CXCR4; Recombinant Fusion Proteins; Triazoles; Virus Internalization

2016
Role of Semen on Vaginal HIV-1 Transmission and Maraviroc Protection.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:12

    Topics: Administration, Intravaginal; Animals; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cyclohexanes; Disease Models, Animal; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Mice; Mice, Transgenic; Semen; Triazoles; Vagina; Viral Load

2015
Differences in the variability of cerebral proton magnetic resonance spectroscopy (1H-MRS) measurements within three HIV-infected cohorts.
    The neuroradiology journal, 2015, Volume: 28, Issue:6

    Topics: Adult; Antiretroviral Therapy, Highly Active; Aspartic Acid; Basal Ganglia; Brain; Brain Chemistry; Cohort Studies; Creatine; Cyclohexanes; Female; Hepatitis C; HIV Fusion Inhibitors; HIV Infections; Humans; Inositol; Magnetic Resonance Imaging; Male; Maraviroc; Middle Aged; Proton Magnetic Resonance Spectroscopy; Protons; Triazoles; Young Adult

2015
Single oral dose of maraviroc does not prevent ex-vivo HIV infection of rectal mucosa in HIV-1 negative human volunteers.
    AIDS (London, England), 2015, Oct-23, Volume: 29, Issue:16

    Topics: Administration, Oral; Adult; Anti-HIV Agents; Biopsy; Cyclohexanes; Healthy Volunteers; HIV Infections; HIV-1; Humans; Intestinal Mucosa; Maraviroc; Models, Biological; Organoids; Treatment Failure; Triazoles

2015
Off-label use of maraviroc in HIV-1-infected paediatric patients in clinical practice.
    AIDS (London, England), 2015, Oct-23, Volume: 29, Issue:16

    Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Off-Label Use; Retrospective Studies; Salvage Therapy; Treatment Outcome; Triazoles; Viral Load; Young Adult

2015
Clinical outcome of maraviroc-containing therapy in heavily pre-treated HIV-1-infected patients.
    International journal of antimicrobial agents, 2016, Volume: 47, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cyclohexanes; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Retrospective Studies; Treatment Outcome; Triazoles; Viral Load; Viral Tropism; Young Adult

2016
Position-specific automated processing of V3 env ultra-deep pyrosequencing data for predicting HIV-1 tropism.
    Scientific reports, 2015, Nov-20, Volume: 5

    Topics: Amino Acid Sequence; Cyclohexanes; Genotype; High-Throughput Nucleotide Sequencing; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Host-Pathogen Interactions; Humans; Maraviroc; Molecular Sequence Data; Peptide Fragments; Phenotype; Point Mutation; Receptors, CCR5; Receptors, CXCR4; Reproducibility of Results; Triazoles; Viral Tropism

2015
Antiretroviral therapy in HIV-1-infected individuals with CD4 count below 100 cells/mm3 results in differential recovery of monocyte activation.
    Journal of leukocyte biology, 2016, Volume: 100, Issue:1

    Topics: Adult; Antiretroviral Therapy, Highly Active; Biomarkers; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Macrophages; Male; Maraviroc; Middle Aged; Monocytes; Triazoles; Viral Load

2016
Is there a role for maraviroc to treat HIV-associated central nervous system white matter disease?
    AIDS (London, England), 2016, Volume: 30, Issue:2

    Topics: Anti-HIV Agents; Cyclohexanes; HIV Infections; Humans; Infant; Infant, Newborn; Leukoencephalopathies; Male; Maraviroc; Treatment Outcome; Triazoles

2016
Short Communication: Limited Anti-HIV-1 Activity of Maraviroc in Mucosal Tissues.
    AIDS research and human retroviruses, 2016, Volume: 32, Issue:4

    Topics: Anti-HIV Agents; Cells, Cultured; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Maraviroc; Models, Biological; Mucous Membrane; Organ Culture Techniques; Treatment Outcome; Triazoles

2016
Durability and Effectiveness of Maraviroc-Containing Regimens in HIV-1-Infected Individuals with Virological Failure in Routine Clinical Practice.
    PloS one, 2015, Volume: 10, Issue:12

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cyclohexanes; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Treatment Outcome; Triazoles; Viral Load

2015
Short Communication: Preferential Killing of HIV Latently Infected CD4(+) T Cells by MALT1 Inhibitor.
    AIDS research and human retroviruses, 2016, Volume: 32, Issue:2

    Topics: Acetanilides; Bryostatins; Caspases; CD4-Positive T-Lymphocytes; Cell Line, Tumor; HIV Infections; HIV-1; Humans; Jurkat Cells; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Neoplasm Proteins; Ribonucleases; Transcription Factors; Triazoles; Virus Activation; Virus Latency; Virus Replication

2016
No selection of CXCR4-using variants in cell reservoirs of dual-mixed HIV-infected patients on suppressive maraviroc therapy.
    AIDS (London, England), 2016, Mar-27, Volume: 30, Issue:6

    Topics: Anti-HIV Agents; Cyclohexanes; Genotype; High-Throughput Nucleotide Sequencing; HIV; HIV Infections; Humans; Leukocytes, Mononuclear; Maraviroc; Selection, Genetic; Triazoles; Viral Tropism

2016
Maraviroc contributes to the restoration of the homeostasis of regulatory T-cell subsets in antiretroviral-naive HIV-infected subjects.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2016, Volume: 22, Issue:5

    Topics: CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Forkhead Transcription Factors; HIV Infections; Homeostasis; Humans; Immunophenotyping; Leukocyte Common Antigens; Longitudinal Studies; Maraviroc; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Triazoles

2016
Laryngotracheal mucormycosis: Report of a case.
    Ear, nose, & throat journal, 2016, Volume: 95, Issue:1

    Topics: Antifungal Agents; Burkitt Lymphoma; Debridement; Dysphonia; Echinocandins; Hepatitis C, Chronic; HIV Infections; Humans; Hyperbaric Oxygenation; Laryngitis; Laryngoscopy; Lipopeptides; Male; Micafungin; Middle Aged; Mucormycosis; Neurosyphilis; Respiratory Distress Syndrome; Respiratory Sounds; Tracheitis; Tracheotomy; Triazoles

2016
Short-term maraviroc exposure, a clinical approach to decide on maraviroc prescription in HIV-1-infected treatment-naïve patients.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Animals; CCR5 Receptor Antagonists; Cyclohexanes; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Triazoles

2016
Maraviroc and reverse transcriptase inhibitors combinations as potential preexposure prophylaxis candidates.
    AIDS (London, England), 2016, Apr-24, Volume: 30, Issue:7

    Topics: Anti-HIV Agents; Cells, Cultured; Chemoprevention; Cyclohexanes; Disease Transmission, Infectious; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Maraviroc; Models, Biological; Organ Culture Techniques; Pre-Exposure Prophylaxis; Reverse Transcriptase Inhibitors; Triazoles

2016
Susceptibility profile and epidemiological cut-off values of Cryptococcus neoformans species complex from Argentina.
    Mycoses, 2016, Volume: 59, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Argentina; Cryptococcosis; Cryptococcus neoformans; Drug Resistance, Fungal; Epidemiologic Methods; Fluconazole; Flucytosine; HIV Infections; Humans; Itraconazole; Meningitis, Cryptococcal; Microbial Sensitivity Tests; Triazoles; Voriconazole

2016
A comparison of two post-processing analysis methods to quantify cerebral metabolites measured via proton magnetic resonance spectroscopy in HIV disease.
    The British journal of radiology, 2016, Volume: 89, Issue:1060

    Topics: Biomarkers; Brain; Brain Diseases; CCR5 Receptor Antagonists; Cyclohexanes; HIV Infections; Humans; Maraviroc; Proton Magnetic Resonance Spectroscopy; Triazoles

2016
Immune Responses to HIV.
    Viral immunology, 2016, Volume: 29, Issue:3

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Cytomegalovirus; Hepacivirus; HIV Antibodies; HIV Infections; HIV-1; Humans; Maraviroc; Receptors, CCR5; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Regulatory; Triazoles

2016
Reduced Frequencies and Activation of Regulatory T Cells After the Treatment of HIV-1-Infected Individuals with the CCR5 Antagonist Maraviroc Are Associated with a Reduction in Viral Loads Rather Than a Direct Effect of the Drug on Regulatory T Cells.
    Viral immunology, 2016, Volume: 29, Issue:3

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Receptors, CCR5; T-Lymphocytes, Regulatory; Triazoles; Viral Load; Virus Replication

2016
Combination Pod-Intravaginal Ring Delivers Antiretroviral Agents for HIV Prophylaxis: Pharmacokinetic Evaluation in an Ovine Model.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6

    Topics: Administration, Intravaginal; Animals; Anti-HIV Agents; Contraceptive Devices, Female; Cyclohexanes; Delayed-Action Preparations; Drug Combinations; Female; HIV Infections; Humans; Maraviroc; Models, Animal; Primary Prevention; Sheep; Tenofovir; Triazoles; Vagina

2016
Author's reply.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Animals; CCR5 Receptor Antagonists; Cyclohexanes; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Triazoles

2016
Rilpivirine and Doravirine Have Complementary Efficacies Against NNRTI-Resistant HIV-1 Mutants.
    Journal of acquired immune deficiency syndromes (1999), 2016, 08-15, Volume: 72, Issue:5

    Topics: Dose-Response Relationship, Drug; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Inhibitory Concentration 50; Models, Molecular; Mutation; Pyridones; Reverse Transcriptase Inhibitors; Rilpivirine; Triazoles; Virus Replication

2016
Factors associated with virological response to a switch regimen containing maraviroc for antiretroviral-experienced HIV-1-infected patients.
    The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:9

    Topics: Adult; Aged; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; CCR5 Receptor Antagonists; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Treatment Outcome; Triazoles; Viral Load

2016
Etiologic Agents and Antifungal Susceptibility of Oral Candidosis from Romanian patients with HIV-infection or type 1 diabetes mellitus.
    Polish journal of microbiology, 2016, Volume: 65, Issue:1

    Topics: Antifungal Agents; Candida; Candidiasis, Oral; Diabetes Complications; Diabetes Mellitus, Type 1; Drug Resistance, Fungal; Fluconazole; HIV Infections; Humans; Microbial Sensitivity Tests; Romania; Triazoles

2016
Maraviroc Reduces Arterial Stiffness in PI-Treated HIV-infected Patients.
    Scientific reports, 2016, 06-29, Volume: 6

    Topics: Atherosclerosis; Carotid Intima-Media Thickness; Case-Control Studies; Cyclohexanes; HIV Fusion Inhibitors; HIV Infections; HIV Protease Inhibitors; Humans; Male; Maraviroc; Risk Factors; Treatment Outcome; Triazoles; Vascular Stiffness

2016
Prevention. Raltegravir, maraviroc show promise as PrEP drugs in studies.
    AIDS policy & law, 2016, Volume: 31, Issue:5

    Topics: Cyclohexanes; HIV Infections; Humans; Maraviroc; Raltegravir Potassium; Triazoles

2016
Characterization of impurities of HIV NNRTI Doravirine by UHPLC-high resolution MS and tandem MS analysis.
    Journal of mass spectrometry : JMS, 2016, Volume: 51, Issue:10

    Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Drug Contamination; HIV Infections; Humans; Molecular Structure; Pyridones; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Triazoles

2016
Exploration of bivalent ligands targeting putative mu opioid receptor and chemokine receptor CCR5 dimerization.
    Bioorganic & medicinal chemistry, 2016, 11-15, Volume: 24, Issue:22

    Topics: Anti-HIV Agents; Cyclohexanes; Dimerization; Dose-Response Relationship, Drug; HIV Infections; HIV-1; Humans; Ligands; Maraviroc; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Naltrexone; Receptors, CCR5; Receptors, Opioid, mu; Structure-Activity Relationship; Triazoles

2016
Addition of maraviroc to antiretroviral therapy decreased interferon-γ mRNA in the CD4+ T cells of patients with suboptimal CD4+ T-cell recovery.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2017, Volume: 23, Issue:1

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Interferon-gamma; Leukocytes, Mononuclear; Male; Maraviroc; Middle Aged; RNA, Messenger; RNA, Viral; Triazoles; Viral Load

2017
Frequency and Env determinants of HIV-1 subtype C strains from antiretroviral therapy-naive subjects that display incomplete inhibition by maraviroc.
    Retrovirology, 2016, Nov-03, Volume: 13, Issue:1

    Topics: Antiretroviral Therapy, Highly Active; CCR5 Receptor Antagonists; CD4 Antigens; Cyclohexanes; HEK293 Cells; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Maraviroc; Mutagenesis; Peptide Fragments; Receptors, CCR5; Triazoles; Virus Internalization

2016
Short Communication: Lack of Effect of Maraviroc Intensification on Blood and Gut Reservoir.
    AIDS research and human retroviruses, 2017, Volume: 33, Issue:2

    Topics: Blood; CCR5 Receptor Antagonists; Cyclohexanes; Gastrointestinal Tract; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Pilot Projects; Prospective Studies; Treatment Outcome; Triazoles

2017
Off-licence use of once-daily maraviroc in children and adolescents with perinatally acquired HIV-1 infection.
    HIV medicine, 2017, Volume: 18, Issue:4

    Topics: Adolescent; CCR5 Receptor Antagonists; Child; Cyclohexanes; Female; HIV Infections; Humans; Male; Maraviroc; Off-Label Use; Retrospective Studies; Treatment Outcome; Triazoles

2017
Effects of Therapy with Maraviroc on the Carotid Intima Media Thickness in HIV-1/HCV Co-infected Patients.
    In vivo (Athens, Greece), 2017, 01-02, Volume: 31, Issue:1

    Topics: Biomarkers; Carotid Intima-Media Thickness; CCR5 Receptor Antagonists; Coinfection; Cyclohexanes; Female; Hepacivirus; Hepatitis C, Chronic; HIV Infections; HIV-1; Humans; Liver Cirrhosis; Male; Maraviroc; Middle Aged; Pilot Projects; Polymerase Chain Reaction; Prospective Studies; Triazoles; Ultrasonography, Doppler, Color

2017
Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation.
    Cell reports, 2017, 01-31, Volume: 18, Issue:5

    Topics: Adolescent; Cell Proliferation; HIV Infections; HIV-1; Humans; Interleukin-2; Lymphocyte Activation; Small Molecule Libraries; STAT5 Transcription Factor; Sumoylation; T-Lymphocytes; Triazoles; Virus Activation; Virus Latency

2017
Strategic use of dual regimens of boosted protease inhibitors plus maraviroc in poorly adherent subjects in view of long-acting drugs: A retrospective study.
    Medicine, 2017, Volume: 96, Issue:7

    Topics: Adult; Cyclohexanes; Drug Therapy, Combination; Female; HIV Fusion Inhibitors; HIV Infections; Humans; Male; Maraviroc; Medication Adherence; Middle Aged; Protease Inhibitors; Retrospective Studies; Triazoles; Young Adult

2017
Can incentives reduce the barriers to use of antenatal care and delivery services in Kenya?: Results of a qualitative inquiry.
    Journal of health care for the poor and underserved, 2017, Volume: 28, Issue:1

    Topics: Delivery, Obstetric; Female; Health Expenditures; Health Knowledge, Attitudes, Practice; Health Services Accessibility; HIV Infections; Humans; Kenya; Maternal Health Services; Mothers; Motivation; Nurses; Patient Acceptance of Health Care; Patient Satisfaction; Pregnancy; Prenatal Care; Qualitative Research; Quality of Health Care; Syphilis; Transportation; Triazoles

2017
Maraviroc: new drug. Multiple antiretroviral treatment failure: too soon to reach conclusions.
    Prescrire international, 2008, Volume: 17, Issue:95

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CCR5 Receptor Antagonists; Cyclohexanes; Drug Approval; Drug Resistance, Multiple; Drug Resistance, Viral; Europe; HIV Infections; Humans; Randomized Controlled Trials as Topic; Treatment Failure; Triazoles; United States

2008
Maraviroc: in vitro assessment of drug-drug interaction potential.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:4

    Topics: Area Under Curve; Atazanavir Sulfate; Cyclohexanes; Cytochrome P-450 CYP3A; Drug Interactions; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Ketoconazole; Liver; Male; Maraviroc; Microsomes, Liver; Oligopeptides; Predictive Value of Tests; Pyridines; Ritonavir; Saquinavir; Triazoles

2008
Anti-HIV agents. Is PF-232798 a possible successor to maraviroc?
    TreatmentUpdate, 2008, Volume: 20, Issue:2

    Topics: Azabicyclo Compounds; CD4 Lymphocyte Count; Cyclohexanes; HIV Fusion Inhibitors; HIV Infections; Humans; Imidazoles; Maraviroc; Piperidines; Triazoles; Tropanes; Viral Load

2008
An in-depth look at the challenges of prescribing maraviroc.
    HIV clinician, 2008,Summer, Volume: 20, Issue:3

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Dose-Response Relationship, Drug; Drug Interactions; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Triazoles

2008
A new class of anti-HIV therapy and new challenges.
    The New England journal of medicine, 2008, Oct-02, Volume: 359, Issue:14

    Topics: Anti-Retroviral Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Resistance, Viral; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Triazoles

2008
Subgroup analyses of maraviroc in previously treated R5 HIV-1 infection.
    The New England journal of medicine, 2008, Oct-02, Volume: 359, Issue:14

    Topics: Adult; Aged; Anti-Retroviral Agents; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Double-Blind Method; Drug Therapy, Combination; Enfuvirtide; Ethnicity; Female; Genotype; Hepatitis B; Hepatitis C; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Odds Ratio; Peptide Fragments; Receptors, CCR5; RNA, Viral; Transaminases; Treatment Outcome; Triazoles; Viral Load

2008
Immune reconstitution syndrome after voriconazole treatment for cryptococcal meningitis in a liver transplant recipient.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2008, Volume: 14, Issue:11

    Topics: Adrenal Cortex Hormones; Anti-Retroviral Agents; Antifungal Agents; Female; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Immune System; Inflammation; Liver Transplantation; Magnetic Resonance Imaging; Meningitis, Cryptococcal; Middle Aged; Pyrimidines; Recurrence; Triazoles; Voriconazole

2008
[Pretreated HIV patients profit from Maraviroc. Oral HIV fusion inhibitor opens new therapy chances].
    MMW Fortschritte der Medizin, 2008, Apr-28, Volume: 150 Spec No 1

    Topics: Administration, Oral; Cyclohexanes; Drug Resistance, Viral; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Randomized Controlled Trials as Topic; Triazoles; Viral Load

2008
New insights into missed endpoint trial.
    AIDS patient care and STDs, 2008, Volume: 22, Issue:11

    Topics: CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; Endpoint Determination; HIV Infections; HIV-1; Humans; Maraviroc; Patient Selection; Receptors, CXCR4; Triazoles

2008
Antiretroviral treatment update from the 17th International AIDS Conference.
    The AIDS reader, 2008, Volume: 18, Issue:11

    Topics: Anti-HIV Agents; Cardiovascular Diseases; CCR5 Receptor Antagonists; Cyclohexanes; HIV Infections; HIV Integrase Inhibitors; Humans; Maraviroc; Pyrrolidinones; Raltegravir Potassium; Reverse Transcriptase Inhibitors; Triazoles

2008
[Introduction. A brief history of AIDS].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 11

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CCR5 Receptor Antagonists; Cyclohexanes; Drug Design; History, 20th Century; History, 21st Century; HIV; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Receptors, CCR5; Triazoles

2008
1-Amido-1-phenyl-3-piperidinylbutanes--CCR5 antagonists for the treatment of HIV: part 2.
    Bioorganic & medicinal chemistry letters, 2009, Mar-01, Volume: 19, Issue:5

    Topics: Animals; Anti-HIV Agents; Butanes; Caco-2 Cells; CCR5 Receptor Antagonists; Cell Line; Dogs; HIV Infections; Humans; Piperidines; Rats; Receptors, CCR5; Stereoisomerism; Triazoles

2009
1,3,4-Oxadiazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 2: SAR of the C5 position.
    Bioorganic & medicinal chemistry letters, 2009, Mar-15, Volume: 19, Issue:6

    Topics: Amino Acid Motifs; Anti-HIV Agents; Chelating Agents; Chemistry, Pharmaceutical; Drug Design; HIV Infections; HIV Integrase Inhibitors; Humans; Metals; Models, Chemical; Molecular Structure; Naphthyridines; Oxadiazoles; Structure-Activity Relationship; Triazoles

2009
The use of oxadiazole and triazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 1: Establishing the pharmacophore.
    Bioorganic & medicinal chemistry letters, 2009, Mar-15, Volume: 19, Issue:6

    Topics: Amino Acid Motifs; Anti-HIV Agents; Chelating Agents; Chemistry, Pharmaceutical; Drug Design; HIV Infections; HIV Integrase Inhibitors; Humans; Models, Chemical; Molecular Structure; Naphthyridines; Oxadiazoles; Structure-Activity Relationship; Triazoles; Virus Replication

2009
Report from the 2008 joint ICAAC/IDSA meeting. Maraviroc vs. efavirenz: a reanalysis of MERIT.
    AIDS clinical care, 2008, Volume: 20, Issue:12

    Topics: Alkynes; Benzoxazines; CCR5 Receptor Antagonists; Cyclohexanes; Cyclopropanes; HIV Infections; Humans; Maraviroc; Reverse Transcriptase Inhibitors; Triazoles

2008
Maraviroc and CD4+ cell count recovery in patients with virologic suppression and blunted CD4+ cell response.
    AIDS (London, England), 2009, Apr-27, Volume: 23, Issue:7

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cyclohexanes; Drug Interactions; HIV Infections; HIV-1; Humans; Maraviroc; Triazoles; Viral Load

2009
Maraviroc: perspectives for use in antiretroviral-naive HIV-1-infected patients.
    The Journal of antimicrobial chemotherapy, 2009, Volume: 63, Issue:6

    Topics: Anti-HIV Agents; Cyclohexanes; HIV Infections; HIV-1; Humans; Maraviroc; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles

2009
In vitro activity of voriconazole against Mexican oral yeast isolates.
    Mycoses, 2010, Volume: 53, Issue:3

    Topics: Adult; Antifungal Agents; Candida; Candidiasis, Oral; Fluconazole; HIV Infections; Humans; Mexico; Microbial Sensitivity Tests; Mouth; Pharynx; Pyrimidines; Triazoles; Voriconazole

2010
Detection of low-frequency pretherapy chemokine (CXC motif) receptor 4 (CXCR4)-using HIV-1 with ultra-deep pyrosequencing.
    AIDS (London, England), 2009, Jun-19, Volume: 23, Issue:10

    Topics: Cyclohexanes; DNA, Viral; Drug Resistance, Viral; Evolution, Molecular; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Phenotype; Phylogeny; Receptors, CXCR4; Sequence Alignment; Sequence Analysis, DNA; Triazoles

2009
CCR5 pharmacology methodologies and associated applications.
    Methods in enzymology, 2009, Volume: 460

    Topics: Animals; Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Discovery; HIV Infections; Humans; Maraviroc; Receptors, CCR5; Triazoles

2009
Maraviroc concentrates in the cervicovaginal fluid and vaginal tissue of HIV-negative women.
    Journal of acquired immune deficiency syndromes (1999), 2009, Aug-15, Volume: 51, Issue:5

    Topics: Adolescent; Adult; Anti-HIV Agents; CCR5 Receptor Antagonists; Cervix Uteri; Cyclohexanes; Female; HIV Infections; HIV Seronegativity; HIV-1; Humans; Maraviroc; Middle Aged; Protein Binding; Triazoles; Vagina; Young Adult

2009
Impact of adding maraviroc to antiretroviral regimens in patients with full viral suppression but impaired CD4 recovery.
    AIDS (London, England), 2009, Sep-10, Volume: 23, Issue:14

    Topics: Aged; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cyclohexanes; Drug Evaluation; Endotoxins; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Retrospective Studies; RNA, Viral; Treatment Outcome; Triazoles

2009
Concurrent use of statins does not influence efficacy of maraviroc in Maraviroc versus Optimized Therapy in Viremic Antiretroviral Treatment-Experienced Patients 1 and 2 trials.
    AIDS (London, England), 2009, Jul-31, Volume: 23, Issue:12

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Drug Interactions; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Maraviroc; Treatment Outcome; Triazoles

2009
Correlation between the Trofile test and virological response to a short-term maraviroc exposure in HIV-infected patients.
    The Journal of antimicrobial chemotherapy, 2009, Volume: 64, Issue:4

    Topics: Adolescent; Adult; Anti-HIV Agents; Child; Cyclohexanes; Female; HIV; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Receptors, HIV; Triazoles; Viral Load; Young Adult

2009
Effects of antifungal agents in sap activity of Candida albicans isolates.
    Mycopathologia, 2010, Volume: 169, Issue:2

    Topics: Antifungal Agents; Aspartic Acid Proteases; Candida albicans; Candidiasis; Culture Media; DNA, Fungal; Drug Resistance, Fungal; Fluconazole; HIV Infections; Humans; Microbial Sensitivity Tests; Mouth Mucosa; Polymerase Chain Reaction; Pyrimidines; Triazoles; Voriconazole

2010
Optimizing care for patients on maraviroc salvage therapy.
    HIV clinician, 2009,Summer, Volume: 21, Issue:3

    Topics: Adult; Cyclohexanes; Drug Interactions; Drug Therapy, Combination; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Middle Aged; Salvage Therapy; Triazoles

2009
Maraviroc modelling strategy: use of early phase 1 data to support a semi-mechanistic population pharmacokinetic model.
    British journal of clinical pharmacology, 2009, Volume: 68, Issue:3

    Topics: Administration, Oral; Anti-HIV Agents; Clinical Trials, Phase I as Topic; Cyclohexanes; Dose-Response Relationship, Drug; Female; HIV Infections; Humans; Injections, Intravenous; Male; Maraviroc; Metabolic Clearance Rate; Models, Biological; Models, Statistical; Triazoles

2009
[New antiretroviral drug classes in HIV therapy].
    MMW Fortschritte der Medizin, 2009, Apr-30, Volume: 151, Issue:18

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; HIV Fusion Inhibitors; HIV Infections; HIV Integrase Inhibitors; HIV-1; Humans; Maraviroc; Piperazines; Pyrimidines; Pyrrolidinones; Quinolones; Raltegravir Potassium; Succinates; Triazoles; Triterpenes; Viral Load

2009
Voriconazole use and pharmacokinetics in combination with interferon-gamma for refractory cryptococcal meningitis in a patient receiving low-dose ritonavir.
    Medical mycology, 2010, Volume: 48, Issue:3

    Topics: Anti-HIV Agents; Antifungal Agents; Cerebrospinal Fluid; Dideoxynucleosides; Drug Monitoring; HIV Infections; Humans; Interferon-gamma; Lamivudine; Male; Meningitis, Cryptococcal; Pyrimidines; Ritonavir; Serum; Triazoles; Voriconazole; Young Adult

2010
[Immunorecovery after prolonged HIV-related immunosuppression: opportunities of the new antiretroviral classes].
    Le infezioni in medicina, 2009, Volume: 17, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cyclohexanes; Darunavir; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Immunocompetence; Interleukin-2; Male; Maraviroc; Middle Aged; Reverse Transcriptase Inhibitors; Sulfonamides; T-Lymphocyte Subsets; Triazoles; Viral Load

2009
Cerebrospinal fluid maraviroc concentrations in HIV-1 infected patients.
    AIDS (London, England), 2009, Nov-27, Volume: 23, Issue:18

    Topics: Adult; CCR5 Receptor Antagonists; Cyclohexanes; HIV Fusion Inhibitors; HIV Infections; Humans; Male; Maraviroc; Mass Spectrometry; Middle Aged; Pilot Projects; Triazoles

2009
Is maraviroc beneficial in paradoxical progressive multifocal leukoencephalopathy-immune reconstitution inflammatory syndrome management?
    AIDS (London, England), 2009, Nov-27, Volume: 23, Issue:18

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Cyclohexanes; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Immune Reconstitution Inflammatory Syndrome; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Maraviroc; Triazoles

2009
Satisfactory cross-cultural validity of the ACTG symptom distress module in HIV-1-infected antiretroviral-naive patients.
    Clinical trials (London, England), 2009, Volume: 6, Issue:6

    Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cultural Competency; Cyclohexanes; Cyclopropanes; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Language; Male; Maraviroc; Middle Aged; Multicenter Studies as Topic; Psychometrics; Randomized Controlled Trials as Topic; Reproducibility of Results; Stress, Psychological; Surveys and Questionnaires; Triazoles; Zidovudine

2009
FDA advisory committee approves Selzentry.
    AIDS patient care and STDs, 2009, Volume: 23, Issue:11

    Topics: Advisory Committees; CCR5 Receptor Antagonists; Cyclohexanes; Drug Approval; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Receptors, CCR5; Triazoles; United States; United States Food and Drug Administration

2009
Molecular docking and 3D-QSAR studies on triazolinone and pyridazinone, non-nucleoside inhibitor of HIV-1 reverse transcriptase.
    Journal of molecular modeling, 2010, Volume: 16, Issue:6

    Topics: Computer Simulation; Drug Design; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Pyridazines; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Triazoles

2010
A validated high-performance liquid chromatography-ultraviolet method for quantification of the CCR5 inhibitor maraviroc in plasma of HIV-infected patients.
    Therapeutic drug monitoring, 2010, Volume: 32, Issue:1

    Topics: CCR5 Receptor Antagonists; Chromatography, High Pressure Liquid; Cyclohexanes; Drug Monitoring; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Reproducibility of Results; Triazoles

2010
Assessment of the pharmacokinetics of co-administered maraviroc and raltegravir.
    British journal of clinical pharmacology, 2010, Volume: 69, Issue:1

    Topics: Adult; Area Under Curve; Chromatography, Liquid; Cyclohexanes; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; HIV Fusion Inhibitors; HIV Infections; HIV Seronegativity; Humans; Male; Maraviroc; Middle Aged; Pyrrolidinones; Raltegravir Potassium; Tandem Mass Spectrometry; Triazoles

2010
Maraviroc for treatment-naive patients with HIV-1 infection: is the glass half empty or half full?
    The Journal of infectious diseases, 2010, Mar-15, Volume: 201, Issue:6

    Topics: Antiviral Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Maraviroc; Triazoles

2010
Raltegravir, maraviroc, etravirine: an effective protease inhibitor and nucleoside reverse transcriptase inhibitor-sparing regimen for salvage therapy in HIV-infected patients with triple-class experience.
    AIDS (London, England), 2010, Mar-27, Volume: 24, Issue:6

    Topics: Adult; Antiretroviral Therapy, Highly Active; Cyclohexanes; Drug Interactions; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Maraviroc; Middle Aged; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Salvage Therapy; Triazoles; Viral Load

2010
Tether influence on the binding properties of tRNALys3 ligands designed by a fragment-based approach.
    Organic & biomolecular chemistry, 2010, Mar-07, Volume: 8, Issue:5

    Topics: Binding Sites; HIV; HIV Infections; Ligands; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Reverse Transcription; RNA, Transfer, Amino Acyl; RNA, Viral; Triazoles

2010
Clinical outcome in resistant HIV-2 infection treated with raltegravir and maraviroc.
    Antiviral research, 2010, Volume: 86, Issue:2

    Topics: Anti-HIV Agents; Cyclohexanes; Drug Resistance, Viral; Genotype; HIV Infections; HIV-2; Humans; Maraviroc; Pyrrolidinones; Raltegravir Potassium; RNA, Viral; Treatment Outcome; Triazoles

2010
Are the proposed env mutations actually associated with resistance to maraviroc?
    Journal of acquired immune deficiency syndromes (1999), 2010, Apr-01, Volume: 53, Issue:4

    Topics: Anti-HIV Agents; Cyclohexanes; Drug Resistance, Viral; env Gene Products, Human Immunodeficiency Virus; HIV Infections; HIV-1; Humans; Maraviroc; Mutation, Missense; Triazoles

2010
Antifungal susceptibility, serotyping, and genotyping of clinical Cryptococcus neoformans isolates collected during 18 years in a single institution in Madrid, Spain.
    Medical mycology, 2010, Volume: 48, Issue:7

    Topics: Amplified Fragment Length Polymorphism Analysis; Antifungal Agents; Comorbidity; Cryptococcosis; Cryptococcus neoformans; Drug Resistance, Fungal; Female; HIV Infections; Hospitals; Humans; Immunocompromised Host; Male; Microbial Sensitivity Tests; Serotyping; Spain; Triazoles

2010
Evaluation of the genotypic prediction of HIV-1 coreceptor use versus a phenotypic assay and correlation with the virological response to maraviroc: the ANRS GenoTropism study.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8

    Topics: Adult; CCR5 Receptor Antagonists; Cyclohexanes; Female; Genotype; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Male; Maraviroc; Middle Aged; Molecular Sequence Data; Phenotype; Receptors, CCR5; Receptors, HIV; Sensitivity and Specificity; Sequence Analysis, DNA; Treatment Outcome; Triazoles; Tropism

2010
Shift in phenotypic susceptibility suggests a competition mechanism in a case of acquired resistance to maraviroc.
    AIDS (London, England), 2010, Jun-01, Volume: 24, Issue:9

    Topics: Adult; Cyclohexanes; Drug Resistance, Viral; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Phenotype; Triazoles

2010
Maraviroc-containing regimen suppresses HIV replication in the cerebrospinal fluid of patients with neurological symptoms.
    AIDS (London, England), 2010, Aug-24, Volume: 24, Issue:13

    Topics: Adult; Anti-HIV Agents; Central Nervous System Diseases; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Triazoles

2010
Protection of rhesus macaques from vaginal infection by vaginally delivered maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor.
    The Journal of infectious diseases, 2010, Sep-01, Volume: 202, Issue:5

    Topics: Administration, Intravaginal; Animals; Anti-HIV Agents; Cyclohexanes; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Macaca mulatta; Maraviroc; Receptors, CCR5; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Treatment Outcome; Triazoles; Vaginal Diseases; Virus Internalization; Virus Replication

2010
Long-term immunovirogical effect and tolerability of a maraviroc-containing regimen in routine clinical practice.
    Current HIV research, 2010, Volume: 8, Issue:6

    Topics: Adult; Anti-HIV Agents; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cyclohexanes; Female; Hepatitis C, Chronic; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Maraviroc; Middle Aged; Pyrrolidinones; Raltegravir Potassium; Retrospective Studies; Spain; Time; Triazoles; Viral Load

2010
The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.
    ChemMedChem, 2010, Nov-08, Volume: 5, Issue:11

    Topics: Amino Acid Sequence; Anti-HIV Agents; Catalytic Domain; CD4 Antigens; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Sequence Data; Peptides; Surface Plasmon Resonance; Thermodynamics; Triazoles

2010
A maraviroc-resistant HIV-1 with narrow cross-resistance to other CCR5 antagonists depends on both N-terminal and extracellular loop domains of drug-bound CCR5.
    Journal of virology, 2010, Volume: 84, Issue:20

    Topics: Base Sequence; Binding Sites; CCR5 Receptor Antagonists; Cell Line; Cohort Studies; Cyclohexanes; DNA Primers; Drug Resistance, Viral; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; In Vitro Techniques; Maraviroc; Models, Biological; Mutant Proteins; Mutation; Peptide Fragments; Protein Structure, Tertiary; Receptors, CCR5; Triazoles

2010
Maraviroc concentrations in cerebrospinal fluid in HIV-infected patients.
    Journal of acquired immune deficiency syndromes (1999), 2010, Dec-15, Volume: 55, Issue:5

    Topics: Adenine; Adult; Anti-HIV Agents; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Chromatography, Liquid; Cyclohexanes; Didanosine; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Tandem Mass Spectrometry; Tenofovir; Triazoles; Viral Load

2010
Analysis of co-receptor usage of circulating viral and proviral HIV genome quasispecies by ultra-deep pyrosequencing in patients who are candidates for CCR5 antagonist treatment.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2011, Volume: 17, Issue:5

    Topics: Adult; Antiretroviral Therapy, Highly Active; CCR5 Receptor Antagonists; Cyclohexanes; Female; Genome, Viral; HIV; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Receptors, CCR5; Receptors, HIV; Sequence Analysis, DNA; Sequence Analysis, RNA; Triazoles; Viral Load

2011
Population-based V3 genotypic tropism assay: a retrospective analysis using screening samples from the A4001029 and MOTIVATE studies.
    AIDS (London, England), 2010, Oct-23, Volume: 24, Issue:16

    Topics: Adult; CD4 Lymphocyte Count; Clinical Trials as Topic; Cyclohexanes; Female; Genotype; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Male; Maraviroc; Receptors, HIV; RNA, Viral; Sequence Analysis, DNA; Triazoles; Viral Load; Viral Tropism

2010
Development and application of a simple LC-MS method for the determination of plasma maraviroc concentrations.
    The journal of medical investigation : JMI, 2010, Volume: 57, Issue:3-4

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Blood Chemical Analysis; CCR5 Receptor Antagonists; Chromatography, Liquid; Cyclohexanes; Drug Monitoring; HIV Infections; HIV-1; Humans; Male; Maraviroc; Mass Spectrometry; Triazoles

2010
Evolution of CCR5 antagonist resistance in an HIV-1 subtype C clinical isolate.
    Journal of acquired immune deficiency syndromes (1999), 2010, Volume: 55, Issue:4

    Topics: Amides; Amino Acid Sequence; Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Resistance, Viral; Evolution, Molecular; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Maraviroc; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Peptide Fragments; Piperazines; Pyrimidines; Quaternary Ammonium Compounds; Receptors, CCR5; Triazoles

2010
Hepatic safety and tolerability in the maraviroc clinical development program.
    AIDS (London, England), 2010, Nov-13, Volume: 24, Issue:17

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; HIV Infections; HIV-1; Humans; Maraviroc; Triazoles

2010
Primary resistance to maraviroc in a large set of R5-V3 viral sequences from HIV-1-infected patients.
    The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:12

    Topics: Anti-HIV Agents; Cyclohexanes; Drug Resistance, Viral; HIV Envelope Protein gp120; HIV Infections; HIV Seropositivity; HIV-1; Humans; Maraviroc; Mutation; Peptide Fragments; Receptors, CCR5; Sequence Analysis, DNA; Triazoles; Viral Tropism

2010
TROCAI (tropism coreceptor assay information): a new phenotypic tropism test and its correlation with Trofile enhanced sensitivity and genotypic approaches.
    Journal of clinical microbiology, 2010, Volume: 48, Issue:12

    Topics: Adult; Anti-HIV Agents; Cyclohexanes; Female; HIV; HIV Infections; Humans; Male; Maraviroc; Microbial Sensitivity Tests; Middle Aged; Triazoles; Viral Tropism; Virus Cultivation

2010
Selective killing of human immunodeficiency virus infected cells by non-nucleoside reverse transcriptase inhibitor-induced activation of HIV protease.
    Retrovirology, 2010, Oct-15, Volume: 7

    Topics: Cell Line; Cells, Cultured; Enzyme Activation; Gene Products, gag; HIV Infections; HIV Protease; HIV-1; Humans; Leukocytes, Mononuclear; Nitriles; Reverse Transcriptase Inhibitors; Sulfonamides; Triazoles

2010
Posaconazole cerebrospinal concentrations in an HIV-infected patient with brain mucormycosis.
    The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:1

    Topics: Africa, Western; AIDS-Related Opportunistic Infections; Antifungal Agents; Brain; CD4 Lymphocyte Count; Central Nervous System Fungal Infections; Cerebrospinal Fluid; HIV Infections; Humans; Inhibitory Concentration 50; Magnetic Resonance Imaging; Mucormycosis; Radiography; Triazoles

2011
Maraviroc does not affect humoral response to the pandemic influenza A-H1N1v 2009 adjuvanted vaccine in HIV-1-infected patients.
    AIDS (London, England), 2010, Nov-27, Volume: 24, Issue:18

    Topics: Adult; Aged; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclohexanes; Disease Outbreaks; Female; HIV Infections; HIV-1; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Maraviroc; Middle Aged; Triazoles

2010
Evaluation of primary resistance to HIV entry inhibitors among brazilian patients failing reverse transcriptase/protease inhibitors treatment reveal high prevalence of maraviroc resistance-related mutations.
    AIDS research and human retroviruses, 2010, Volume: 26, Issue:12

    Topics: Adult; Ambulatory Care Facilities; Anti-HIV Agents; Brazil; Cyclohexanes; DNA, Viral; Drug Resistance, Viral; Enfuvirtide; env Gene Products, Human Immunodeficiency Virus; Female; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Male; Maraviroc; Middle Aged; Molecular Sequence Data; Mutation, Missense; Peptide Fragments; Piperazines; Prevalence; Proviruses; Sequence Analysis, DNA; Treatment Failure; Triazoles

2010
The use of the SAEM algorithm in MONOLIX software for estimation of population pharmacokinetic-pharmacodynamic-viral dynamics parameters of maraviroc in asymptomatic HIV subjects.
    Journal of pharmacokinetics and pharmacodynamics, 2011, Volume: 38, Issue:1

    Topics: Algorithms; Computer Simulation; Cyclohexanes; HIV; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Models, Statistical; Research Design; Software; Triazoles; Viral Load

2011
Cost-effectiveness of maraviroc for antiretroviral treatment-experienced HIV-infected individuals in Mexico.
    Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2010, Volume: 13, Issue:8

    Topics: Computer Simulation; Cost-Benefit Analysis; Cyclohexanes; Female; HIV Fusion Inhibitors; HIV Infections; Humans; Male; Maraviroc; Mexico; Middle Aged; Models, Biological; Quality-Adjusted Life Years; Triazoles

2010
New insights into the mechanisms whereby low molecular weight CCR5 ligands inhibit HIV-1 infection.
    The Journal of biological chemistry, 2011, Feb-18, Volume: 286, Issue:7

    Topics: Allosteric Regulation; Chemokine CCL3; Cyclohexanes; Guanosine Triphosphate; HEK293 Cells; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Ligands; Maraviroc; Protein Binding; Receptors, CCR5; Triazoles

2011
Discordance rates between Trofile test and short-term virological response to maraviroc.
    Antiviral research, 2011, Volume: 89, Issue:2

    Topics: Adolescent; Adult; Anti-HIV Agents; Child; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Treatment Outcome; Triazoles; Viral Tropism; Young Adult

2011
The evolutionary analysis of emerging low frequency HIV-1 CXCR4 using variants through time--an ultra-deep approach.
    PLoS computational biology, 2010, Dec-16, Volume: 6, Issue:12

    Topics: Algorithms; Computational Biology; Cyclohexanes; Genetic Variation; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Receptors, CXCR4; Sequence Alignment; Sequence Analysis, RNA; Software; Triazoles; Viral Tropism

2010
Comparison of phenotypic and genotypic tropism determination in triple-class-experienced HIV patients eligible for maraviroc treatment.
    The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:2

    Topics: Cyclohexanes; Genotype; HIV Infections; HIV-1; Humans; Maraviroc; Phenotype; Receptors, CCR5; Receptors, CXCR4; Triazoles; Viral Tropism

2011
Oral pre-exposure prophylaxis by anti-retrovirals raltegravir and maraviroc protects against HIV-1 vaginal transmission in a humanized mouse model.
    PloS one, 2010, Dec-21, Volume: 5, Issue:12

    Topics: Administration, Oral; Animals; Anti-HIV Agents; Cyclohexanes; Disease Models, Animal; Female; Flow Cytometry; HIV Infections; HIV-1; Humans; Maraviroc; Mice; Mice, Transgenic; Post-Exposure Prophylaxis; Pyrrolidinones; Raltegravir Potassium; Triazoles; Vagina

2010
It's official...but not infallible.
    Prescrire international, 2010, Volume: 19, Issue:110

    Topics: Cyclohexanes; Drug Approval; Europe; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Off-Label Use; Triazoles; United States

2010
Deep sequencing to infer HIV-1 co-receptor usage: application to three clinical trials of maraviroc in treatment-experienced patients.
    The Journal of infectious diseases, 2011, Jan-15, Volume: 203, Issue:2

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Cyclohexanes; env Gene Products, Human Immunodeficiency Virus; Genotype; High-Throughput Nucleotide Sequencing; HIV Infections; HIV-1; Humans; Maraviroc; Receptors, CCR5; Receptors, HIV; Retrospective Studies; RNA, Viral; Triazoles; Viral Tropism; Virology; Virus Attachment

2011
Drug interactions between voriconazole, darunavir/ritonavir and etravirine in an HIV-infected patient with Aspergillus pneumonia.
    AIDS (London, England), 2011, Feb-20, Volume: 25, Issue:4

    Topics: Anti-Retroviral Agents; Aspergillosis; Aspergillus; Drug Interactions; Female; HIV Infections; HIV-1; Humans; Male; Nitriles; Pneumonia, Aspiration; Pyridazines; Pyrimidines; Ritonavir; Triazoles; Voriconazole

2011
Cost-effectiveness of optimized background therapy plus maraviroc for previously treated patients with R5 HIV-1 infection from the perspective of the Spanish health care system.
    Clinical therapeutics, 2010, Volume: 32, Issue:13

    Topics: Adult; Aged; Anti-HIV Agents; CCR5 Receptor Antagonists; Cost-Benefit Analysis; Cyclohexanes; Drug Therapy, Combination; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Markov Chains; Middle Aged; Models, Economic; National Health Programs; Quality-Adjusted Life Years; Spain; Triazoles; Young Adult

2010
HIV-1 dual/mixed tropic isolates show different genetic and phenotypic characteristics and response to maraviroc in vitro.
    Antiviral research, 2011, Volume: 90, Issue:1

    Topics: Anti-HIV Agents; Cell Line; Cyclohexanes; High-Throughput Nucleotide Sequencing; HIV Envelope Protein gp120; HIV Envelope Protein gp41; HIV Infections; HIV-1; Humans; Maraviroc; Molecular Sequence Data; Receptors, Virus; Triazoles; Viral Tropism; Virus Attachment; Virus Replication

2011
Agonist-induced internalization of CC chemokine receptor 5 as a mechanism to inhibit HIV replication.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 337, Issue:3

    Topics: Animals; Anti-HIV Agents; Benzeneacetamides; CCR5 Receptor Antagonists; Cell Line; Chemokine CCL5; Chemokines; Chemotaxis; Cricetinae; Cyclohexanes; DNA Replication; Drug Resistance, Multiple, Viral; HEK293 Cells; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Macrophages; Maraviroc; Protein Binding; Receptors, CCR5; Receptors, CXCR4; Sulfonamides; Triazoles; Virus Replication

2011
Maraviroc is able to inhibit dual-R5 viruses in a dual/mixed HIV-1-infected patient.
    The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:4

    Topics: Anti-HIV Agents; Cell Line; Cyclohexanes; Genotype; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Treatment Outcome; Triazoles; Viral Tropism

2011
Synergistic inhibition of R5 HIV-1 by maraviroc and CCR5 antibody HGS004 in primary cells: implications for treatment and prevention.
    AIDS (London, England), 2011, Jun-01, Volume: 25, Issue:9

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Maraviroc; Receptors, CCR5; Triazoles

2011
Oral Candida isolates among HIV-infected subjects in Nigeria.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2011, Volume: 44, Issue:3

    Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Candida; Candidiasis, Oral; Drug Resistance, Fungal; Female; Fluconazole; Flucytosine; HIV Infections; Humans; Itraconazole; Male; Microbial Sensitivity Tests; Middle Aged; Mycological Typing Techniques; Nigeria; Pyrimidines; Triazoles; Voriconazole

2011
Mutations in gp41 are correlated with coreceptor tropism but do not improve prediction methods substantially.
    Antiviral therapy, 2011, Volume: 16, Issue:3

    Topics: Algorithms; Amino Acid Sequence; Anti-HIV Agents; Cyclohexanes; HIV Envelope Protein gp41; HIV Infections; HIV-1; Humans; Maraviroc; Molecular Sequence Data; Mutation; Predictive Value of Tests; Receptors, CCR5; Receptors, CXCR4; Reverse Transcriptase Inhibitors; Treatment Outcome; Triazoles; Tropism

2011
Baseline CD4(+) T-cell counts and weighted background susceptibility scores strongly predict response to maraviroc regimens in treatment-experienced patients.
    Antiviral therapy, 2011, Volume: 16, Issue:3

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Clinical Trials, Phase III as Topic; Cyclohexanes; Drug Resistance, Viral; Genotype; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Logistic Models; Maraviroc; Microbial Sensitivity Tests; Phenotype; Predictive Value of Tests; RNA, Viral; T-Lymphocytes; Treatment Outcome; Triazoles; Viral Load

2011
Maraviroc intensification for suboptimal CD4⁺ T cell response in a perinatally HIV-infected adolescent.
    AIDS (London, England), 2011, Jun-01, Volume: 25, Issue:9

    Topics: Adolescent; CD4-Positive T-Lymphocytes; Cyclohexanes; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Male; Maraviroc; Pregnancy; Pregnancy Complications, Infectious; Triazoles

2011
[CCR5 antagonist Maraviroc: effective and well tolerated. "A very promising substance"].
    MMW Fortschritte der Medizin, 2011, May-05, Volume: 153, Issue:18

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Therapy, Combination; Genotype; HIV Infections; HIV-1; Humans; Maraviroc; Medication Adherence; Triazoles

2011
[Utilizing the potential of maraviroc early. "Clear in second line therapy" (interview by Dr. Felicitas Zorn)].
    MMW Fortschritte der Medizin, 2011, May-05, Volume: 153, Issue:18

    Topics: Anti-HIV Agents; Cyclohexanes; Drug Therapy, Combination; Early Diagnosis; Genotype; HIV Infections; HIV-1; Humans; Maraviroc; Triazoles

2011
Pharmacokinetics of the raltegravir/maraviroc/etravirine combination.
    The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:8

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cyclohexanes; Female; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Nitriles; Pyridazines; Pyrimidines; Pyrrolidinones; Raltegravir Potassium; Salvage Therapy; Triazoles

2011
A topical microbicide gel formulation of CCR5 antagonist maraviroc prevents HIV-1 vaginal transmission in humanized RAG-hu mice.
    PloS one, 2011, Volume: 6, Issue:6

    Topics: Animals; Anti-Infective Agents, Local; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Chemistry, Pharmaceutical; Cyclohexanes; Disease Models, Animal; DNA-Binding Proteins; Female; Gels; HIV Infections; HIV-1; Homeodomain Proteins; Humans; Maraviroc; Mice; Placebos; Triazoles; Vagina

2011
Virological response after short-term CCR5 antagonist exposure in HIV-infected patients: frequency of subjects with virological response and associated factors.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:10

    Topics: Adult; Anti-HIV Agents; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cell Line; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Receptors, CXCR4; RNA, Viral; Triazoles; Viral Load

2011
Deep sequencing of plasma and proviral HIV-1 to establish coreceptor usage: what is the clinical impact of the quasispecies distribution?
    The Journal of infectious diseases, 2011, Sep-15, Volume: 204, Issue:6

    Topics: Anti-HIV Agents; Cyclohexanes; HIV Infections; HIV-1; Humans; Receptors, HIV; Triazoles; Viral Tropism; Virology

2011
Non-aqueous silicone elastomer gels as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, Dec-10, Volume: 156, Issue:2

    Topics: Administration, Intravaginal; Animals; Cyclohexanes; Delayed-Action Preparations; Female; Gels; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Macaca mulatta; Maraviroc; Silicone Elastomers; Triazoles; Vagina; Vaginal Creams, Foams, and Jellies

2011
Arylazolylthioacetanilide. Part 8: Design, synthesis and biological evaluation of novel 2-(2-(2,4-dichlorophenyl)-2H-1,2,4-triazol-3-ylthio)-N-arylacetamides as potent HIV-1 inhibitors.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:10

    Topics: Acetamides; Anti-HIV Agents; Cell Line; HIV Infections; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Triazoles; Virus Replication

2011
Maraviroc concentrations in seminal plasma in HIV-infected patients.
    Journal of acquired immune deficiency syndromes (1999), 2010, Dec-15, Volume: 55, Issue:5

    Topics: Adult; Anti-Retroviral Agents; CCR5 Receptor Antagonists; Chromatography, Liquid; Cyclohexanes; HIV Infections; HIV-1; Humans; Male; Maraviroc; Mass Spectrometry; Middle Aged; Semen; Triazoles

2010
In vitro effect of anti-human immunodeficiency virus CCR5 antagonist maraviroc on chemotactic activity of monocytes, macrophages and dendritic cells.
    Clinical and experimental immunology, 2011, Volume: 166, Issue:2

    Topics: CCR5 Receptor Antagonists; Chemokine CCL2; Chemokine CCL4; Chemokine CCL5; Chemotaxis; Chemotaxis, Leukocyte; Cyclohexanes; Dendritic Cells; HIV Fusion Inhibitors; HIV Infections; Humans; Macrophages; Maraviroc; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Receptors, CCR5; Triazoles

2011
Modulatory effects of the CCR5 antagonist maraviroc on microglial pro-inflammatory activation elicited by gp120.
    Journal of neurochemistry, 2012, Volume: 120, Issue:1

    Topics: Animals; Blotting, Western; CCR5 Receptor Antagonists; Cell Survival; Cells, Cultured; Cyclohexanes; Cytokines; Dinoprostone; DNA Primers; HIV Envelope Protein gp120; HIV Infections; Inflammation; Interferon-gamma; Macrophage Activation; Maraviroc; Microglia; Nitric Oxide; Rats; Real-Time Polymerase Chain Reaction; RNA, Messenger; Triazoles

2012
Rescue of HIV-1 long-time archived X4 strains to escape maraviroc.
    Antiviral research, 2011, Volume: 92, Issue:3

    Topics: Antiretroviral Therapy, Highly Active; Base Sequence; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Genotype; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Maraviroc; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Receptors, CCR5; Receptors, CXCR4; Sequence Alignment; Treatment Failure; Triazoles; Viral Load; Viral Tropism

2011
Penicillium marneffei infection presenting as vulv-ulcer in an HIV-infected woman.
    European journal of medical research, 2011, Sep-12, Volume: 16, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Diagnosis, Differential; Female; HIV; HIV Infections; Humans; Mycoses; Penicillium; Pyrimidines; Triazoles; Ulcer; Voriconazole; Vulvar Diseases; Young Adult

2011
HIV-1 predisposed to acquiring resistance to maraviroc (MVC) and other CCR5 antagonists in vitro has an inherent, low-level ability to utilize MVC-bound CCR5 for entry.
    Retrovirology, 2011, Nov-07, Volume: 8

    Topics: CCR5 Receptor Antagonists; Cell Line; Cyclohexanes; Drug Resistance, Viral; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Protein Binding; Receptors, CCR5; Triazoles; Virus Internalization

2011
[Pulmonary aspergillosis and HIV infection: about two cases].
    Revue de pneumologie clinique, 2012, Volume: 68, Issue:1

    Topics: Adult; Antifungal Agents; Aspergillosis; Bronchoalveolar Lavage; HIV Infections; Humans; Lung Diseases, Fungal; Male; Middle Aged; Prognosis; Pulmonary Aspergillosis; Pyrimidines; Radiography; Risk Factors; Triazoles; Voriconazole

2012
In vitro phenotypic susceptibility of HIV-2 clinical isolates to CCR5 inhibitors.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Cells, Cultured; Cyclohexanes; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV-1; HIV-2; Humans; Inhibitory Concentration 50; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Maraviroc; Models, Biological; Phytohemagglutinins; Receptors, CCR5; Receptors, CXCR4; Species Specificity; Triazoles; Virus Replication

2012
Correlation of the virological response to short-term maraviroc monotherapy with standard and deep-sequencing-based genotypic tropism prediction methods.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:3

    Topics: Adult; Algorithms; CCR5 Receptor Antagonists; Chromatography, High Pressure Liquid; Cyclohexanes; Female; Genotype; High-Throughput Nucleotide Sequencing; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Molecular Typing; Receptors, CCR5; RNA, Viral; Tandem Mass Spectrometry; Treatment Outcome; Triazoles; Viral Load; Viral Tropism

2012
Once daily maraviroc 300 mg or 150 mg in combination with ritonavir-boosted darunavir 800/100 mg.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:3

    Topics: Adult; Anti-HIV Agents; Cyclohexanes; Darunavir; Drug Interactions; Female; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Retrospective Studies; Ritonavir; Sulfonamides; Triazoles

2012
In vitro downregulation of matrix metalloproteinase-9 in rat glial cells by CCR5 antagonist maraviroc: therapeutic implication for HIV brain infection.
    PloS one, 2011, Volume: 6, Issue:12

    Topics: Animals; Astrocytes; Brain; CCR5 Receptor Antagonists; Cell Death; Cell Shape; Cell Survival; Cells, Cultured; Cyclohexanes; Down-Regulation; Gene Expression Regulation, Enzymologic; HIV Infections; Humans; Lipopolysaccharides; Maraviroc; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neuroglia; Rats; Receptors, CCR5; RNA, Messenger; Tetradecanoylphorbol Acetate; Triazoles

2011
Can the flow of medicines be improved? Fundamental pharmacokinetic and pharmacological principles toward improving Phase II survival.
    Drug discovery today, 2012, Volume: 17, Issue:9-10

    Topics: Aminopyridines; Animals; CCR5 Receptor Antagonists; Clinical Trials, Phase II as Topic; Cyclohexanes; Drug Evaluation; HIV Infections; Humans; Maraviroc; Morpholines; Neuralgia; Pharmaceutical Preparations; Pharmacokinetics; Receptors, Dopamine D3; Sexual Dysfunction, Physiological; Triazoles

2012
Differential use of CCR5 by HIV-1 clinical isolates resistant to small-molecule CCR5 antagonists.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:4

    Topics: Amino Acid Sequence; Amino Acid Substitution; Anti-HIV Agents; Antibodies, Blocking; Antibodies, Monoclonal; CCR5 Receptor Antagonists; Cyclohexanes; Drug Resistance, Viral; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Piperazines; Pyrimidines; Receptors, CCR5; Triazoles

2012
Lack of short-term increase in serum mediators of fibrogenesis and in non-invasive markers of liver fibrosis in HIV/hepatitis C virus-coinfected patients starting maraviroc-based antiretroviral therapy.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2012, Volume: 31, Issue:8

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Biomarkers; Cyclohexanes; Female; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Liver Cirrhosis; Male; Maraviroc; Matrix Metalloproteinase 2; Middle Aged; Pilot Projects; Prospective Studies; RNA, Viral; Serum; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Triazoles

2012
Responses to switching to maraviroc-based antiretroviral therapy in treated patients with suppressed plasma HIV-1-RNA load.
    Intervirology, 2012, Volume: 55, Issue:2

    Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Ki-1 Antigen; Lymphocyte Activation; Male; Maraviroc; Middle Aged; Plasma; RNA, Viral; Treatment Outcome; Triazoles; Viral Load; Viral Tropism

2012
Baseline susceptibility of primary HIV-2 to entry inhibitors.
    Antiviral therapy, 2012, Volume: 17, Issue:3

    Topics: Amides; Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; Enfuvirtide; Female; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV-1; HIV-2; Humans; Inhibitory Concentration 50; Male; Maraviroc; Microbial Sensitivity Tests; Peptide Fragments; Quaternary Ammonium Compounds; Triazoles

2012
Antiviral effect of maraviroc in semen: a case report.
    Antiviral therapy, 2012, Volume: 17, Issue:5

    Topics: Adult; Antiretroviral Therapy, Highly Active; Cyclohexanes; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Semen; Sperm Count; Triazoles; Viral Load

2012
Lower than expected maraviroc concentrations in cerebrospinal fluid exceed the wild-type CC chemokine receptor 5-tropic HIV-1 50% inhibitory concentration.
    AIDS (London, England), 2012, Apr-24, Volume: 26, Issue:7

    Topics: Adult; CCR5 Receptor Antagonists; Chromatography, Reverse-Phase; Cross-Sectional Studies; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Inhibitory Concentration 50; Male; Maraviroc; Middle Aged; RNA, Viral; Tandem Mass Spectrometry; Triazoles

2012
Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:5

    Topics: Administration, Intravaginal; Animals; Anti-HIV Agents; Biopsy; CCR5 Receptor Antagonists; Chromatography, High Pressure Liquid; Contraceptive Devices, Female; Cyclohexanes; Delayed-Action Preparations; Female; HIV Infections; HIV-1; Humans; Longitudinal Studies; Macaca mulatta; Maraviroc; Medroxyprogesterone Acetate; Pyrazoles; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tissue Distribution; Triazoles; Vagina; Valine; Virus Internalization

2012
Evolution of proviral DNA HIV-1 tropism under selective pressure of maraviroc-based therapy.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:6

    Topics: Adult; Anti-HIV Agents; Cyclohexanes; DNA, Viral; Evolution, Molecular; Female; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Proviruses; Selection, Genetic; Triazoles; Viral Tropism

2012
Impaired maraviroc and raltegravir clearance in a human immunodeficiency virus-infected patient with end-stage liver disease and renal impairment: a management dilemma.
    Pharmacotherapy, 2012, Volume: 32, Issue:1

    Topics: Adult; Cyclohexanes; Disease Management; End Stage Liver Disease; Fatal Outcome; HIV Infections; Humans; Male; Maraviroc; Metabolic Clearance Rate; Pyrrolidinones; Raltegravir Potassium; Renal Insufficiency; Triazoles

2012
Drug interactions between voriconazole, darunavir/ritonavir and etravirine in an HIV-infected patient with Aspergillus pneumonia.
    AIDS (London, England), 2012, Mar-27, Volume: 26, Issue:6

    Topics: Aspergillosis; Female; HIV Infections; Humans; Male; Pneumonia, Aspiration; Pyridazines; Pyrimidines; Ritonavir; Triazoles

2012
CCR5 antagonist TD-0680 uses a novel mechanism for enhanced potency against HIV-1 entry, cell-mediated infection, and a resistant variant.
    The Journal of biological chemistry, 2012, May-11, Volume: 287, Issue:20

    Topics: Amides; Anti-HIV Agents; Binding Sites; CCR5 Receptor Antagonists; Cell Line; Cyclohexanes; HIV Infections; HIV-1; Humans; Maraviroc; Protein Structure, Secondary; Quaternary Ammonium Compounds; Receptors, CCR5; Sulfonamides; Triazoles; Tropanes; Virus Internalization; Virus Replication

2012
Genetically encoded photo-cross-linkers map the binding site of an allosteric drug on a G protein-coupled receptor.
    ACS chemical biology, 2012, Jun-15, Volume: 7, Issue:6

    Topics: Allosteric Site; CCR5 Receptor Antagonists; Cross-Linking Reagents; Cyclohexanes; HEK293 Cells; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Receptors, CCR5; Triazoles; Ultraviolet Rays; Virus Internalization

2012
[Cerebral aspergillosis in an human immunodeficiency virus infected patient].
    Enfermedades infecciosas y microbiologia clinica, 2012, Volume: 30, Issue:6

    Topics: Adult; AIDS Serodiagnosis; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antifungal Agents; Brain Edema; Cytomegalovirus Infections; Female; HIV Infections; Humans; Magnetic Resonance Imaging; Morocco; Neuroaspergillosis; Serratia Infections; Toxoplasmosis, Cerebral; Triazoles

2012
Macaque studies of vaccine and microbicide combinations for preventing HIV-1 sexual transmission.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, May-29, Volume: 109, Issue:22

    Topics: Administration, Intravaginal; AIDS Vaccines; Animals; Anti-Infective Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Therapy, Combination; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Macaca mulatta; Maraviroc; RNA, Viral; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Treatment Outcome; Triazoles; Viral Load

2012
Immune recovery and T cell subset analysis during effective treatment with maraviroc.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:10

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Antigens; Cyclohexanes; Female; HIV Infections; Humans; Immunophenotyping; Male; Maraviroc; Middle Aged; Receptors, CCR5; Receptors, CXCR4; T-Lymphocyte Subsets; Treatment Outcome; Triazoles

2012
Levels of soluble endothelial protein C receptor are associated with CD4+ changes in Maraviroc-treated HIV-infected patients.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Adult; Aged; Antigens, CD; Biomarkers; Blood Coagulation; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Endothelial Protein C Receptor; Endothelium, Vascular; Female; Follow-Up Studies; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Receptors, Cell Surface; Triazoles

2012
Long-term maraviroc use as salvage therapy in HIV-2 infection.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:10

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Cyclohexanes; Drug Monitoring; HIV Infections; HIV-2; Humans; Maraviroc; Salvage Therapy; Treatment Outcome; Triazoles

2012
Patients on a combined antiretroviral therapy after maraviroc clinical test show no immunovirological impairment.
    Antiviral research, 2012, Volume: 95, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Child; Cyclohexanes; Female; Follow-Up Studies; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Treatment Outcome; Triazoles; Viral Load; Viral Tropism; Young Adult

2012
Pharmacokinetic interaction between maraviroc and etravirine in HIV-infected patients receiving regimens containing both drugs and no ritonavir-boosted protease inhibitor.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:11

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cyclohexanes; Drug Interactions; Female; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Multicenter Studies as Topic; Nitriles; Plasma; Pyridazines; Pyrimidines; Ritonavir; Triazoles

2012
High prevalence of X4/DM-tropic variants in children and adolescents infected with HIV-1 by vertical transmission.
    The Pediatric infectious disease journal, 2012, Volume: 31, Issue:10

    Topics: Adolescent; Anti-HIV Agents; CCR5 Receptor Antagonists; Child; Cross-Sectional Studies; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Male; Maraviroc; Prevalence; Receptors, HIV; Salvage Therapy; Triazoles; Viral Tropism

2012
An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data.
    Retrovirology, 2012, Jul-25, Volume: 9

    Topics: Amino Acid Sequence; Benzylamines; CCR5 Receptor Antagonists; Computational Biology; Cyclams; Cyclohexanes; Genetic Vectors; HEK293 Cells; Heterocyclic Compounds; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Models, Biological; Molecular Sequence Data; Multivariate Analysis; Phenotype; Receptors, CCR5; Receptors, CXCR4; Transfection; Triazoles; Virus Internalization

2012
Stochastic model of in-vivo X4 emergence during HIV infection: implications for the CCR5 inhibitor maraviroc.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: CCR5 Receptor Antagonists; CD4-Positive T-Lymphocytes; Cyclohexanes; HIV Infections; Humans; Maraviroc; Models, Theoretical; Triazoles

2012
Maraviroc observational study: the impact of expanded resistance testing and clinical considerations for antiretroviral regimen selection in treatment-experienced patients.
    AIDS research and human retroviruses, 2013, Volume: 29, Issue:1

    Topics: Adult; Anti-HIV Agents; Cyclohexanes; Drug Resistance, Viral; HIV; HIV Fusion Inhibitors; HIV Infections; Humans; Male; Maraviroc; Microbial Sensitivity Tests; Salvage Therapy; Treatment Failure; Triazoles

2013
Effect of maraviroc on HIV disease progression-related biomarkers.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:11

    Topics: Adult; Antiretroviral Therapy, Highly Active; Biomarkers; CCR5 Receptor Antagonists; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclohexanes; Disease Progression; Female; Fibrin Fibrinogen Degradation Products; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Lipopolysaccharide Receptors; Lymphocyte Activation; Lymphocyte Count; Male; Maraviroc; Middle Aged; Receptors, CCR5; RNA, Viral; Triazoles; Viral Load

2012
Prevalence and antifungal susceptibility of Candida parapsilosis complex isolates collected from oral cavities of HIV-infected individuals.
    Journal of medical microbiology, 2012, Volume: 61, Issue:Pt 12

    Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis, Oral; Caspofungin; Echinocandins; Female; Fluconazole; HIV Infections; Humans; Lipopeptides; Male; Microbial Sensitivity Tests; Mouth; Mycological Typing Techniques; Polymorphism, Restriction Fragment Length; Pyrimidines; Triazoles; Voriconazole

2012
Successful salvage therapy of refractory HIV-related cryptococcal meningitis with the combination of liposomal amphotericin B, voriconazole, and recombinant interferon-γ.
    Diagnostic microbiology and infectious disease, 2012, Volume: 74, Issue:4

    Topics: Adult; Amphotericin B; Antifungal Agents; Drug Therapy, Combination; HIV Infections; Humans; Interferon-gamma; Male; Meningitis, Cryptococcal; Middle Aged; Pyrimidines; Salvage Therapy; Treatment Outcome; Triazoles; Voriconazole

2012
The CD4/CD8 ratio in HIV-infected subjects is independently associated with T-cell activation despite long-term viral suppression.
    The Journal of infection, 2013, Volume: 66, Issue:1

    Topics: Adult; Anti-Retroviral Agents; Bacterial Translocation; CD4-CD8 Ratio; Clinical Trials, Phase II as Topic; Cross-Sectional Studies; Cyclohexanes; Female; HIV Infections; Host-Pathogen Interactions; Humans; Lymphocyte Activation; Male; Maraviroc; Middle Aged; Multivariate Analysis; Pyrrolidinones; Raltegravir Potassium; Risk Factors; Statistics, Nonparametric; T-Lymphocytes; Triazoles; Viral Load

2013
Monitoring the emergence of resistance mutations in patients infected with HIV-1 under salvage therapy with raltegravir in Rio de Janeiro, Brazil: a follow-up study.
    Journal of medical virology, 2012, Volume: 84, Issue:12

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Brazil; CD4 Lymphocyte Count; Cyclohexanes; Drug Resistance, Viral; Enfuvirtide; Follow-Up Studies; Genotyping Techniques; HIV Envelope Protein gp41; HIV Infections; HIV Integrase; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Maraviroc; Mutation; Peptide Fragments; Prospective Studies; Pyrrolidinones; Raltegravir Potassium; RNA, Viral; Salvage Therapy; Treatment Outcome; Triazoles; Viral Load; Virus Replication

2012
HIV-1 dynamics and coreceptor usage in Maraviroc-treated patients with ongoing replication.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Drug Resistance, Viral; Evolution, Molecular; Genotype; High-Throughput Nucleotide Sequencing; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Maraviroc; Peptide Fragments; Receptors, CCR5; Receptors, CXCR4; Selection, Genetic; Sequence Analysis, RNA; Triazoles; Viral Tropism

2013
Non-natural peptide triazole antagonists of HIV-1 envelope gp120.
    ChemMedChem, 2013, Volume: 8, Issue:2

    Topics: Amino Acid Sequence; Anti-HIV Agents; Calorimetry; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Peptides; Peptidomimetics; Protein Binding; Triazoles

2013
Pharmacokinetic interaction of maraviroc with tacrolimus in a patient coinfected with HIV and hepatitis B virus following hepatic transplant due to hepatocellular carcinoma.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:4

    Topics: Anti-HIV Agents; Carcinoma, Hepatocellular; Cyclohexanes; Drug Interactions; Hepatitis B; HIV Infections; Humans; Immunosuppressive Agents; Liver Transplantation; Male; Maraviroc; Middle Aged; Plasma; Tacrolimus; Treatment Outcome; Triazoles

2013
BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.
    Cell cycle (Georgetown, Tex.), 2013, Feb-01, Volume: 12, Issue:3

    Topics: Azepines; Benzodiazepines; CD4-Positive T-Lymphocytes; Cell Cycle Proteins; Cells, Cultured; HEK293 Cells; Heterocyclic Compounds, 4 or More Rings; HIV Infections; HIV-1; Humans; Jurkat Cells; Nuclear Proteins; Positive Transcriptional Elongation Factor B; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; RNA Interference; RNA, Small Interfering; tat Gene Products, Human Immunodeficiency Virus; Transcription Factors; Transcription, Genetic; Triazoles; Virus Latency

2013
A silicone elastomer vaginal ring for HIV prevention containing two microbicides with different mechanisms of action.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Feb-14, Volume: 48, Issue:3

    Topics: Calorimetry, Differential Scanning; CCR5 Receptor Antagonists; Contraceptive Devices, Female; Cyclohexanes; Delayed-Action Preparations; Drug Combinations; Drug Delivery Systems; Drug Stability; Drug Storage; HIV Infections; HIV Reverse Transcriptase; Hot Temperature; Maraviroc; Mechanical Phenomena; Pyrimidines; Reverse Transcriptase Inhibitors; Silicone Elastomers; Solubility; Triazoles

2013
Transmitted/founder and chronic HIV-1 envelope proteins are distinguished by differential utilization of CCR5.
    Journal of virology, 2013, Volume: 87, Issue:5

    Topics: CCR5 Receptor Antagonists; CD4-Positive T-Lymphocytes; Cell Line; Cyclohexanes; env Gene Products, Human Immunodeficiency Virus; HEK293 Cells; HIV Infections; HIV-1; Humans; Maraviroc; Receptors, CCR5; Triazoles; Virus Attachment; Virus Internalization

2013
Impact of antiretroviral pressure on selection of primary human immunodeficiency virus type 1 envelope sequences in vitro.
    The Journal of general virology, 2013, Volume: 94, Issue:Pt 5

    Topics: Amino Acid Sequence; Anti-HIV Agents; Base Sequence; Cyclohexanes; DNA, Viral; Genetic Variation; Genotype; Glycosylation; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Lamivudine; Maraviroc; Molecular Sequence Data; Phylogeny; Pyrrolidinones; Raltegravir Potassium; Receptors, CCR5; Receptors, CXCR4; Saquinavir; Sequence Analysis, DNA; Triazoles; Viral Tropism

2013
Long-term suppressive combined antiretroviral treatment does not normalize the serum level of soluble CD14.
    The Journal of infectious diseases, 2013, Apr-15, Volume: 207, Issue:8

    Topics: Adult; Aged; Anti-Retroviral Agents; Case-Control Studies; CD4 Lymphocyte Count; Cyclohexanes; Female; HIV Infections; HIV-1; Humans; Lipopolysaccharide Receptors; Longitudinal Studies; Male; Maraviroc; Middle Aged; RNA, Viral; Solubility; Time Factors; Treatment Outcome; Triazoles; Viral Load

2013
Pharmacokinetics of maraviroc, raltegravir, darunavir, and etravirine in the semen of HIV-infected men.
    Journal of acquired immune deficiency syndromes (1999), 2013, Feb-01, Volume: 62, Issue:2

    Topics: Anti-HIV Agents; Area Under Curve; Cyclohexanes; Darunavir; HIV Infections; Humans; Male; Maraviroc; Middle Aged; Nitriles; Prospective Studies; Pyridazines; Pyrimidines; Pyrrolidinones; Raltegravir Potassium; Semen; Sulfonamides; Triazoles

2013
Impact of antiretroviral therapy duration and intensification on isolated shedding of HIV-1 RNA in semen.
    The Journal of infectious diseases, 2013, Apr-15, Volume: 207, Issue:8

    Topics: Amino Acid Sequence; Anti-Retroviral Agents; Base Sequence; Case-Control Studies; Cyclohexanes; HIV Infections; HIV-1; Humans; Incidence; Male; Maraviroc; Molecular Sequence Data; Prospective Studies; Pyrrolidinones; Raltegravir Potassium; RNA, Viral; Semen; Sequence Analysis, RNA; Sexual Behavior; Time Factors; Treatment Outcome; Triazoles; Viral Load; Viremia; Virus Shedding

2013
Pharmacokinetic profile and safety of 150 mg of maraviroc dosed with 800/100 mg of darunavir/ritonavir all once daily, with and without nucleoside analogues, in HIV-infected subjects.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:6

    Topics: Adult; Antiretroviral Therapy, Highly Active; Area Under Curve; CD4 Lymphocyte Count; Cyclohexanes; Darunavir; Drug Therapy, Combination; Female; Half-Life; HIV Fusion Inhibitors; HIV Infections; HIV Protease Inhibitors; Humans; Male; Maraviroc; Middle Aged; Prospective Studies; Ritonavir; RNA, Viral; Sulfonamides; Triazoles

2013
Frequency of amino acid changes associated with resistance to attachment inhibitor BMS-626529 in R5- and X4-tropic HIV-1 subtype B.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:6

    Topics: Amino Acid Sequence; Amino Acid Substitution; Anti-HIV Agents; CD4 Antigens; Drug Resistance, Viral; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Piperazines; Real-Time Polymerase Chain Reaction; Triazoles; Viral Tropism; Virus Attachment

2013
Changes in susceptibility to posaconazole in clinical isolates of Candida albicans.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 53, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candida albicans; Candidiasis, Oral; Drug Resistance, Fungal; Genes, Viral; HIV Infections; Humans; Microbial Sensitivity Tests; Mutation; Triazoles

2004
[Successful treatment with voriconazol of a Pseudallescheria boydii fungus ball in a HIV positive patient and previous tuberculosis].
    Revista iberoamericana de micologia, 2003, Volume: 20, Issue:2

    Topics: Adult; Antifungal Agents; Female; HIV Infections; Humans; Lung Diseases, Fungal; Pseudallescheria; Pyrimidines; Remission Induction; Triazoles; Tuberculosis, Pulmonary; Voriconazole

2003
Multiple mutations in human immunodeficiency virus-1 integrase confer resistance to the clinical trial drug S-1360.
    AIDS (London, England), 2004, Oct-21, Volume: 18, Issue:15

    Topics: Anti-HIV Agents; Cells, Cultured; Clone Cells; Drug Resistance, Viral; Furans; HIV Infections; HIV Integrase; HIV-1; Humans; Mutation; Phenotype; Polymerase Chain Reaction; Triazoles; Virus Replication

2004
What does "culture of life" mean for an undocumented immigrant?
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Oct-15, Volume: 41, Issue:8

    Topics: Adult; Antifungal Agents; Clinical Trials as Topic; Coccidioidomycosis; Emigration and Immigration; Ethics, Medical; HIV Infections; Humans; Male; Mexico; Transients and Migrants; Triazoles; United States

2005
Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1.
    Nature medicine, 2005, Volume: 11, Issue:11

    Topics: Anti-HIV Agents; Area Under Curve; CCR5 Receptor Antagonists; Clinical Trials, Phase II as Topic; Cyclohexanes; Dose-Response Relationship, Drug; HIV Infections; HIV-1; Humans; Maraviroc; Randomized Controlled Trials as Topic; RNA, Viral; Time Factors; Treatment Outcome; Triazoles; Viral Load

2005
Organic chemistry at the interface to biology.
    Chembiochem : a European journal of chemical biology, 2006, Volume: 7, Issue:5

    Topics: Awards and Prizes; Biology; CCR5 Receptor Antagonists; Chemistry, Organic; Cyclohexanes; DNA; Drug Design; Drug Evaluation, Preclinical; HIV Infections; Humans; Maraviroc; Photochemistry; Signal Transduction; Solar Energy; Triazoles

2006
First case of Penicillium marneffei fungemia in Greece and strain susceptibility to five licensed systemic antifungal agents and posaconazole.
    The American journal of the medical sciences, 2006, Volume: 332, Issue:1

    Topics: Antifungal Agents; Drug Resistance, Bacterial; Fungemia; Greece; HIV Infections; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Penicillium; Triazoles

2006
A modified Christensen's urea and CLSI broth microdilution method for testing susceptibilities of six Malassezia species to voriconazole, itraconazole, and ketoconazole.
    Journal of clinical microbiology, 2006, Volume: 44, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Culture Media; Dermatomycoses; HIV Infections; Humans; Itraconazole; Ketoconazole; Malassezia; Microbial Sensitivity Tests; Polysorbates; Pyrimidines; Triazoles; Urea; Voriconazole

2006
A novel nonnucleoside analogue that inhibits human immunodeficiency virus type 1 isolates resistant to current nonnucleoside reverse transcriptase inhibitors.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2

    Topics: Administration, Oral; Alkynes; Animals; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Dogs; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Mutation; Reverse Transcriptase Inhibitors; Triazoles

2007
The latest in antiretroviral therapy.
    Drug news & perspectives, 2006, Volume: 19, Issue:8

    Topics: Anti-HIV Agents; Anti-Retroviral Agents; Antibodies, Monoclonal; Antiretroviral Therapy, Highly Active; Clinical Trials as Topic; Cyclohexanes; Darunavir; Drugs, Investigational; HIV Infections; HIV-1; Humans; Maraviroc; Nitriles; Organic Chemicals; Piperazines; Pyridazines; Pyrimidines; Pyrrolidinones; Raltegravir Potassium; Receptors, Chemokine; Sulfonamides; Treatment Outcome; Triazoles

2006
Rapid discovery and structure-activity profiling of novel inhibitors of human immunodeficiency virus type 1 protease enabled by the copper(I)-catalyzed synthesis of 1,2,3-triazoles and their further functionalization.
    Journal of medicinal chemistry, 2006, Dec-28, Volume: 49, Issue:26

    Topics: Catalysis; Combinatorial Chemistry Techniques; Computer Simulation; Copper; Crystallography, X-Ray; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Triazoles; Virus Replication

2006
Reduced maximal inhibition in phenotypic susceptibility assays indicates that viral strains resistant to the CCR5 antagonist maraviroc utilize inhibitor-bound receptor for entry.
    Journal of virology, 2007, Volume: 81, Issue:5

    Topics: Amino Acid Sequence; Amino Acid Substitution; CCR5 Receptor Antagonists; Cell Line; Cyclohexanes; Drug Resistance, Viral; Genes, env; Genetic Variation; HIV Envelope Protein gp120; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; In Vitro Techniques; Lymphocytes; Maraviroc; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phenotype; Receptors, CXCR4; Triazoles; Virus Cultivation; Virus Replication

2007
Researchers buoyed by novel HIV drugs: will expand drug arsenal against resistant virus.
    JAMA, 2007, Apr-11, Volume: 297, Issue:14

    Topics: Anti-HIV Agents; Cyclohexanes; Drug Resistance, Viral; Drugs, Investigational; HIV Fusion Inhibitors; HIV Infections; HIV Integrase Inhibitors; Humans; Maraviroc; Organic Chemicals; Pyrrolidinones; Raltegravir Potassium; Triazoles

2007
Anti-HIV agents. New drugs, new hope, old lessons.
    TreatmentUpdate, 2007, Volume: 19, Issue:2

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Cyclopropanes; HIV Infections; HIV Integrase Inhibitors; Humans; Lipodystrophy; Maraviroc; Organic Chemicals; Pyrrolidinones; Raltegravir Potassium; Triazoles; Viral Load

2007
New HIV drug classes on the horizon.
    Nature reviews. Drug discovery, 2007, Volume: 6, Issue:4

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Cyclohexanes; Drug Resistance, Viral; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Receptors, CCR5; Receptors, CXCR4; Triazoles

2007
Acquired resistance to echinocandins in Candida albicans: case report and review.
    The Journal of antimicrobial chemotherapy, 2007, Volume: 59, Issue:6

    Topics: Adult; Amino Acid Sequence; Amino Acid Substitution; Amphotericin B; Antifungal Agents; Candida albicans; Candidiasis; Caspofungin; Drug Resistance, Fungal; Echinocandins; Fluconazole; Genotype; HIV Infections; HIV-1; Humans; Lipopeptides; Lipoproteins; Male; Micafungin; Microbial Sensitivity Tests; Molecular Sequence Data; Peptides, Cyclic; Pyrimidines; Treatment Failure; Triazoles; Voriconazole

2007
Identifying safety concerns from genetic data: lessons from the development of CCR5 inhibitors.
    Antiviral therapy, 2007, Volume: 12, Issue:2

    Topics: Arthritis, Rheumatoid; CCR5 Receptor Antagonists; Cyclohexanes; Drug Design; Genotype; Hepatitis C; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Meta-Analysis as Topic; Multiple Sclerosis; Mutation; Pharmacogenetics; Receptors, CCR5; Research Design; Risk Assessment; Risk Factors; Triazoles

2007
Pivotal moments in HIV treatment: the 14th CROI.
    The AIDS reader, 2007, Volume: 17, Issue:5

    Topics: Anti-Retroviral Agents; Clinical Trials as Topic; Congresses as Topic; Cyclohexanes; HIV Fusion Inhibitors; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lopinavir; Maraviroc; Multicenter Studies as Topic; Organic Chemicals; Pyrimidinones; Pyrrolidinones; Raltegravir Potassium; Treatment Outcome; Triazoles; United States

2007
Advances in HIV therapeutics: the 14th CROI.
    The AIDS reader, 2007, Volume: 17, Issue:5

    Topics: Acyclovir; Anti-HIV Agents; Circumcision, Male; Cyclohexanes; Dideoxynucleosides; Drug Interactions; Female; Hepatitis C; HIV Fusion Inhibitors; HIV Infections; Humans; Male; Maraviroc; Multicenter Studies as Topic; Nitriles; Organic Chemicals; Pyridazines; Pyrimidines; Pyrrolidinones; Raltegravir Potassium; Randomized Controlled Trials as Topic; Triazoles

2007
More data on maraviroc in treatment-experienced patients.
    AIDS patient care and STDs, 2007, Volume: 21, Issue:5

    Topics: Cyclohexanes; Drugs, Investigational; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Treatment Outcome; Triazoles

2007
FDA panel backs HIV drug.
    The AIDS reader, 2007, Volume: 17, Issue:6

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Drug Approval; HIV Infections; Humans; Maraviroc; Triazoles; United States; United States Food and Drug Administration

2007
Posaconazole for the management of mucosal candidiasis.
    Future microbiology, 2007, Volume: 2, Issue:3

    Topics: Antifungal Agents; Antiretroviral Therapy, Highly Active; Candidiasis, Oral; HIV Infections; Humans; Molecular Structure; Randomized Controlled Trials as Topic; Triazoles

2007
Images in HIV/AIDS. Invasive aspergillosis presenting as a neck mass in a person with HIV/AIDS.
    The AIDS reader, 2007, Volume: 17, Issue:7

    Topics: Adult; Antifungal Agents; Antiretroviral Therapy, Highly Active; Aspergillosis; Fatal Outcome; HIV Infections; Humans; Male; Neck; Pyrimidines; Tomography, X-Ray Computed; Triazoles; Voriconazole

2007
Report from the XVI International HIV Drug Resistance Workshop.
    AIDS clinical care, 2007, Volume: 19, Issue:8

    Topics: Anti-HIV Agents; Cyclohexanes; Drug Resistance, Viral; HIV Fusion Inhibitors; HIV Infections; HIV Integrase Inhibitors; Humans; Lopinavir; Maraviroc; Nitriles; Piperazines; Pyridazines; Pyrimidines; Pyrimidinones; Triazoles

2007
First medication in new class of ARTs poised to be available for salvage therapy. Tropism testing helps determine best patients for drug.
    AIDS alert, 2007, Volume: 22, Issue:8

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; HIV Infections; Humans; Maraviroc; Salvage Therapy; Triazoles; Tropism; Viral Load

2007
Novel HIV treatment approved.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2007, Sep-15, Volume: 64, Issue:18

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Drug Approval; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Triazoles

2007
FDA approves maraviroc tablets.
    AIDS patient care and STDs, 2007, Volume: 21, Issue:9

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Drug Approval; HIV Infections; Humans; Maraviroc; Tablets; Triazoles; United States; United States Food and Drug Administration

2007
Changes in HIV-1 tropism: clinical and prognostic consequences.
    European journal of medical research, 2007, Oct-15, Volume: 12, Issue:9

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; HIV Infections; HIV-1; Humans; Maraviroc; Prognosis; Receptors, CCR5; Receptors, CXCR4; Triazoles

2007
Maraviroc reduces viral load in naive patients at 48 weeks.
    AIDS patient care and STDs, 2007, Volume: 21, Issue:9

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Clinical Trials as Topic; Cyclohexanes; Cyclopropanes; HIV Infections; HIV-1; Humans; Maraviroc; Triazoles; Viral Load

2007
Maraviroc approved in the European Union.
    AIDS patient care and STDs, 2007, Volume: 21, Issue:10

    Topics: Anti-HIV Agents; Controlled Clinical Trials as Topic; Cyclohexanes; Drug Approval; European Union; HIV Infections; Humans; Maraviroc; Triazoles

2007
Post-exposure prophylaxis with a maraviroc-containing regimen after occupational exposure to a multi-resistant HIV-infected source person.
    Journal of medical virology, 2008, Volume: 80, Issue:1

    Topics: Adult; Anti-HIV Agents; Cyclohexanes; Drug Resistance, Multiple, Viral; Health Personnel; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Patient-to-Professional; Male; Maraviroc; Middle Aged; Needlestick Injuries; Occupational Exposure; Triazoles

2008
Maraviroc (Celsentri) for multidrug-resistant human immunodeficiency virus (HIV)-1.
    Issues in emerging health technologies, 2007, Issue:110

    Topics: Adult; Anti-HIV Agents; Anti-Retroviral Agents; Canada; CD4 Lymphocyte Count; Cyclohexanes; Drug Approval; Drug Resistance, Viral; Europe; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Lymphocytes; Randomized Controlled Trials as Topic; Receptors, CCR5; Receptors, CXCR4; Treatment Outcome; Triazoles; Tropism; United States; Viral Load

2007
Two new drugs for HIV infection.
    The Medical letter on drugs and therapeutics, 2008, Jan-14, Volume: 50, Issue:1277

    Topics: Administration, Oral; CCR5 Receptor Antagonists; Cyclohexanes; Drug Administration Schedule; Drug Costs; Drug Interactions; Drug Resistance, Viral; HIV Fusion Inhibitors; HIV Infections; HIV Integrase Inhibitors; HIV-1; Humans; Maraviroc; Organic Chemicals; Pyrrolidinones; Raltegravir Potassium; Treatment Outcome; Triazoles

2008
A review of the clinical pharmacology of maraviroc. Introduction.
    British journal of clinical pharmacology, 2008, Volume: 65 Suppl 1

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Maraviroc; Triazoles

2008
A receptor theory-based semimechanistic PD model for the CCR5 noncompetitive antagonist maraviroc.
    British journal of clinical pharmacology, 2008, Volume: 65 Suppl 1

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Computer Simulation; Cyclohexanes; HIV Infections; Humans; Maraviroc; Models, Biological; Models, Statistical; Triazoles; Viral Load

2008
Report from the 4th IAS Conference on HIV Pathogenesis, Treatment and Prevention. Maraviroc in treatment-experienced and treatment-naive patients.
    AIDS clinical care, 2007, Volume: 19, Issue:10

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Cyclohexanes; HIV Infections; Humans; Maraviroc; Treatment Outcome; Triazoles

2007
FDA notifications. Maraviroc approved as a CCR5 co-receptor antagonist.
    AIDS alert, 2007, Volume: 22, Issue:9

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Drug Approval; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Triazoles; United States; United States Food and Drug Administration; Viral Load

2007
[New drugs for HIV infection].
    Revue de l'infirmiere, 2008, Issue:138

    Topics: Anti-HIV Agents; Contraindications; Cyclohexanes; Darunavir; Drug Monitoring; HIV Infections; Humans; Maraviroc; Nitriles; Organic Chemicals; Patient Education as Topic; Patient Selection; Pyridazines; Pyrimidines; Pyrrolidinones; Raltegravir Potassium; Sulfonamides; Triazoles

2008
Multifocal squamous cell carcinomas in an HIV-infected patient with a long-term voriconazole therapy.
    AIDS (London, England), 2008, Apr-23, Volume: 22, Issue:7

    Topics: Antifungal Agents; Carcinoma, Squamous Cell; HIV; HIV Infections; Humans; Male; Middle Aged; Pyrimidines; Skin Neoplasms; Triazoles; Voriconazole

2008
[CCR5 antagonists: a new class of antiretrovirals].
    Medecine et maladies infectieuses, 2008, Volume: 38 Suppl 1

    Topics: Benzoates; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclohexanes; Diketopiperazines; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Piperazines; Pyrimidines; Spiro Compounds; Triazoles

2008
[Clinical pharmacokinetic of maraviroc].
    Medecine et maladies infectieuses, 2008, Volume: 38 Suppl 1

    Topics: CCR5 Receptor Antagonists; Cyclohexanes; Drug Interactions; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Triazoles

2008
[Maraviroc: clinical trials results].
    Medecine et maladies infectieuses, 2008, Volume: 38 Suppl 1

    Topics: Clinical Trials as Topic; Clinical Trials, Phase II as Topic; Cyclohexanes; HIV Fusion Inhibitors; HIV Infections; Humans; Maraviroc; Triazoles

2008
In vitro activities of voriconazole (UK-109,496) against fluconazole-susceptible and -resistant Candida albicans isolates from oral cavities of patients with human immunodeficiency virus infection.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:3

    Topics: Antifungal Agents; Candida albicans; Candidiasis, Oral; Drug Resistance, Microbial; Fluconazole; HIV Infections; Humans; Microbial Sensitivity Tests; Mouth; Pyrimidines; Triazoles; Voriconazole

1997
Detection of Candida dubliniensis in oropharyngeal samples from human immunodeficiency virus-infected patients in North America by primary CHROMagar candida screening and susceptibility testing of isolates.
    Journal of clinical microbiology, 1998, Volume: 36, Issue:10

    Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Candida; Candidiasis, Oral; Fluconazole; Genotype; HIV Infections; Humans; Itraconazole; Microbial Sensitivity Tests; Mouth; North America; Pharynx; Phenotype; Pyrimidines; Triazoles; Voriconazole

1998
Is there in vivo-in vitro correlation between antifungal susceptibility, species of Candida spp. and clinical outcome?
    International journal of antimicrobial agents, 2000, Volume: 16, Issue:4

    Topics: Antifungal Agents; Candida; Candidiasis; Clinical Trials as Topic; HIV Infections; Humans; Microbial Sensitivity Tests; Neoplasms; Statistics as Topic; Treatment Outcome; Triazoles

2000
Synergism of voriconazole and terbinafine against Candida albicans isolates from human immunodeficiency virus-infected patients with oropharyngeal candidiasis.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candida albicans; Candidiasis; Drug Resistance, Microbial; Drug Synergism; HIV Infections; Humans; Microbial Sensitivity Tests; Naphthalenes; Pharyngitis; Pyrimidines; Terbinafine; Triazoles; Voriconazole

2001
Genotyping and antifungal susceptibility of human subgingival Candida albicans isolates.
    Archives of oral biology, 2002, Volume: 47, Issue:3

    Topics: Adult; Amphotericin B; Antifungal Agents; Candida albicans; Dental Plaque; DNA, Fungal; Drug Resistance, Fungal; Female; Fluconazole; Genetic Heterogeneity; HIV Infections; Humans; Itraconazole; Karyotyping; Male; Microbial Sensitivity Tests; Mycological Typing Techniques; Triazoles

2002
Researchers explore new anti-HIV agents.
    JAMA, 2002, Apr-03, Volume: 287, Issue:13

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Clinical Trials as Topic; Cyclic N-Oxides; Drugs, Investigational; Enfuvirtide; Furans; HIV; HIV Envelope Protein gp120; HIV Envelope Protein gp41; HIV Infections; HIV Integrase Inhibitors; Humans; Nitriles; Oximes; Peptide Fragments; Piperazines; Piperidines; Pyridazines; Pyridines; Pyrimidines; Reverse Transcriptase Inhibitors; Triazoles

2002
In vitro activities of terbinafine in combination with fluconazole, itraconazole, voriconazole, and posaconazole against clinical isolates of Candida glabrata with decreased susceptibility to azoles.
    Journal of clinical microbiology, 2002, Volume: 40, Issue:5

    Topics: Antifungal Agents; Azoles; Candida; Dose-Response Relationship, Drug; Fluconazole; HIV Infections; Humans; Itraconazole; Laboratories; Microbial Sensitivity Tests; Mouth; Naphthalenes; Pyrimidines; Quality Control; Terbinafine; Triazoles; Voriconazole

2002
Pharmacokinetics of SCH-39304 in human immunodeficiency virus-infected patients following chronic oral dosing.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:12

    Topics: Administration, Oral; Adult; Antifungal Agents; Candidiasis, Oral; Drug Administration Schedule; HIV Infections; HIV-1; Humans; Male; Middle Aged; Triazoles

1992