Page last updated: 2024-08-24

triazoles and Granulocytic Leukemia, Chronic

triazoles has been researched along with Granulocytic Leukemia, Chronic in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (15.00)29.6817
2010's14 (70.00)24.3611
2020's3 (15.00)2.80

Authors

AuthorsStudies
Carrà, G; Guerrasio, A; Morotti, A; Russo, I1
Beaver, LP; Clair, PM; Deininger, MW; Eiring, AM; Hare, TO; Heaton, WL; Mason, CC; Pomicter, AD; Senina, A; Shacham, S; Than, H; Yan, D1
Cheng, G; Huang, L; Li, T; Luo, X; Xue, X; Zhang, Y1
Kang, KW; Kim, BS; Kim, JH; Lee, BH; Lee, SJ; Park, Y1
Chilov, GG; Dutikova, YV; Ivanova, ES; Kalinina, AA; Khamidullina, AI; Novikov, FN; Shtil, AA; Shunaev, AV; Tatarskiy, VV; Yastrebova, MA; Zeifman, AA1
Apperley, J; Caligiuri, MA; Eisfeld, AK; Ellis, JJ; Ferenchak, G; Gabrail, NY; Garzon, R; Goldman, JM; Harb, JG; Hokland, P; Kauffman, MG; Landesman, Y; Marcucci, G; Milojkovic, D; Neviani, P; Oaks, JJ; Perrotti, D; Reid, A; Roy, DC; Santhanam, R; Shacham, S; Smith, CL; Walker, CJ1
Abraham, SA; Holyoake, TL1
Brill, B; Chilov, G; Haberbosch, I; Hoelzer, D; Metodieva, A; Mian, AA; Novikov, F; Ottmann, OG; Rafiei, A; Ruthardt, M; Stroganov, O; Stroylov, V; Titov, I; Zeifman, A1
Bonneau, K; Bowler, AD; Chenchik, A; Deininger, MW; Eiring, AM; Gantz, KC; Heaton, WL; Iovino, AJ; Kauffman, M; Khorashad, JS; Kraft, IL; Mason, CC; O'Hare, T; Pomicter, AD; Redwine, HM; Reynolds, KR; Shacham, S; Tantravahi, SK; Ullman, KS; Yu, F; Zabriskie, MS1
Bae, E; Gu, YK; Hirao, A; Ishihara, K; Jeong, ES; Jin, CH; Jomen, Y; Kim, DH; Kim, DK; Kim, DW; Kim, SJ; Krause, DS; Li, S; Naka, K; Ooshima, A; Oshima, H; Oshima, M; Sheen, YY; Takihara, Y1
Choi, CW; Kang, MH; Kim, DS; Na, YJ; Yoon, SY1
Ben-Batalla, I; Bokemeyer, C; Brümmendorf, TH; Carmeliet, P; Clark, RE; Erdmann, R; Ernst, T; Helgason, GV; Hochhaus, A; Holyoake, TL; Jørgensen, H; Koschmieder, S; Loges, S; Mitchell, R; Mitra, S; Pantel, K; Rankin, S; Schafhausen, P; Schultze, A; Vandenberghe, P; Velthaus, JL; von Amsberg, G1
Amdouni, H; Auberger, P; Benhida, R; Bougrin, K; Driowya, M; Dubois, A; Dufies, M; Furstoss, N; Lacas-Gervais, S; Martin, AR; Métier, C; Orange, F; Robert, G; Zerhouni, M1
Alessandro, R; Arlinghaus, R; Corrado, C; Flugy, AM; Fontana, S; Iovino, F; Kohn, EC; Leo, GD; Marfia, A; Raimondo, S; Santoro, A; Stassi, G1
Auberger, P; Benhida, R; Bougrin, K; Driowya, M; Puissant, A; Robert, G1
Alessandro, R; Corrado, C; De Leo, G; Flugy, AM; Guggino, G; Karmali, R; Raimondo, S; Taverna, S1
Buendía, B; Cuenca-Estrella, M; De La Camara, R; Mellado, E; Rodriguez-Tudela, JL1
Jagirdar, J; Scott, RS; Sutton, DA1
Decosterd, LA; Duchosal, MA; Gambillara, E; Kovacsovics, T; Laffitte, E; Panizzon, RG; Widmer, N1
Alessandro, R; Colomba, P; Corrado, C; De Leo, G; Flugy, AM; Fontana, S; Giordano, M; Kohn, EC; Santoro, A1

Reviews

1 review(s) available for triazoles and Granulocytic Leukemia, Chronic

ArticleYear
Nuclear-cytoplasmic Shuttling in Chronic Myeloid Leukemia: Implications in Leukemia Maintenance and Therapy.
    Cells, 2019, 10-14, Volume: 8, Issue:10

    Topics: Apoptosis; Cell Nucleus; Cytoplasm; Cytosol; Exportin 1 Protein; Humans; Hydrazines; Karyopherins; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Nuclear Export Signals; Nuclear Localization Signals; Receptors, Cytoplasmic and Nuclear; Triazoles

2019

Other Studies

19 other study(ies) available for triazoles and Granulocytic Leukemia, Chronic

ArticleYear
Coordinated inhibition of nuclear export and Bcr-Abl1 selectively targets chronic myeloid leukemia stem cells.
    Leukemia, 2020, Volume: 34, Issue:6

    Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Hematopoietic Stem Cells; Humans; Hydrazines; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Neoplastic Stem Cells; Triazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2020
Differential Impacts of Azole Antifungal Drugs on the Pharmacokinetic Profiles of Dasatinib in Rats by LC-MS-MS.
    Current drug metabolism, 2020, Volume: 21, Issue:13

    Topics: Administration, Oral; Animals; Antifungal Agents; Area Under Curve; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dasatinib; Drug Interactions; Drug Monitoring; Humans; Itraconazole; Ketoconazole; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Models, Animal; Protein Kinase Inhibitors; Rats; Tandem Mass Spectrometry; Triazoles; Voriconazole

2020
CXCR2, a novel target to overcome tyrosine kinase inhibitor resistance in chronic myelogenous leukemia cells.
    Biochemical pharmacology, 2021, Volume: 190

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Drug Resistance, Neoplasm; Female; Humans; Imatinib Mesylate; Interleukin-8; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Phenylurea Compounds; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Receptors, Interleukin-8B; Triazoles; Young Adult

2021
PF‑114, a novel selective inhibitor of BCR‑ABL tyrosine kinase, is a potent inducer of apoptosis in chronic myelogenous leukemia cells.
    International journal of oncology, 2019, Volume: 55, Issue:1

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Fusion Proteins, bcr-abl; HL-60 Cells; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mutation; Phosphorylation; Pyridines; STAT3 Transcription Factor; Triazoles; Xenograft Model Antitumor Assays

2019
Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias.
    Blood, 2013, Oct-24, Volume: 122, Issue:17

    Topics: Adult; Animals; Antigens, CD34; Antineoplastic Agents; Apoptosis; Cell Proliferation; Clinical Trials, Phase I as Topic; DNA-Binding Proteins; Drug Evaluation, Preclinical; Exportin 1 Protein; Fusion Proteins, bcr-abl; Gene Expression Regulation, Leukemic; Histone Chaperones; Humans; Hydrazines; Karyopherins; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Protein Transport; Receptors, Cytoplasmic and Nuclear; Ribonucleoproteins; Transcription Factors; Triazoles

2013
Redirecting traffic using the XPO1 police.
    Blood, 2013, Oct-24, Volume: 122, Issue:17

    Topics: Animals; Antineoplastic Agents; Exportin 1 Protein; Gene Expression Regulation, Leukemic; Humans; Hydrazines; Karyopherins; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Cytoplasmic and Nuclear; Triazoles

2013
PF-114, a potent and selective inhibitor of native and mutated BCR/ABL is active against Philadelphia chromosome-positive (Ph+) leukemias harboring the T315I mutation.
    Leukemia, 2015, Volume: 29, Issue:5

    Topics: Animals; Antigens, Ly; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA Mutational Analysis; Female; fms-Like Tyrosine Kinase 3; Fusion Proteins, bcr-abl; Humans; Imidazoles; Inhibitory Concentration 50; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Proteins; Mice; Mice, Inbred C57BL; Models, Molecular; Mutagenesis; Mutation; Point Mutation; Proto-Oncogene Proteins c-kit; Pyridazines; Pyridines; Translocation, Genetic; Triazoles; Xenograft Model Antitumor Assays

2015
shRNA library screening identifies nucleocytoplasmic transport as a mediator of BCR-ABL1 kinase-independent resistance.
    Blood, 2015, Mar-12, Volume: 125, Issue:11

    Topics: Active Transport, Cell Nucleus; Benzamides; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Exportin 1 Protein; Fusion Proteins, bcr-abl; Gene Knockdown Techniques; Gene Library; Humans; Hydrazines; Imatinib Mesylate; K562 Cells; Karyopherins; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mutation; Piperazines; Protein Kinase Inhibitors; Pyrimidines; ran GTP-Binding Protein; Receptors, Cytoplasmic and Nuclear; RNA, Small Interfering; Signal Transduction; Triazoles; Tumor Stem Cell Assay

2015
Novel oral transforming growth factor-β signaling inhibitor EW-7197 eradicates CML-initiating cells.
    Cancer science, 2016, Volume: 107, Issue:2

    Topics: Aniline Compounds; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Disease Models, Animal; Humans; Imidazoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred C57BL; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridazines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Transfection; Transforming Growth Factor beta; Triazoles

2016
Use of deferasirox, an iron chelator, to overcome imatinib resistance of chronic myeloid leukemia cells.
    The Korean journal of internal medicine, 2016, Volume: 31, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Benzoates; Cell Proliferation; Deferasirox; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; G1 Phase Cell Cycle Checkpoints; Humans; Imatinib Mesylate; Iron Chelating Agents; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Protein Kinase Inhibitors; Signal Transduction; Triazoles

2016
Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor-Sensitive and -Resistant Chronic Myeloid Leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2017, May-01, Volume: 23, Issue:9

    Topics: Animals; Apoptosis; Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Imidazoles; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Pyridazines; Receptor Protein-Tyrosine Kinases; Small Molecule Libraries; Triazoles

2017
In Vitro and in Vivo Evaluation of Fully Substituted (5-(3-Ethoxy-3-oxopropynyl)-4-(ethoxycarbonyl)-1,2,3-triazolyl-glycosides as Original Nucleoside Analogues to Circumvent Resistance in Myeloid Malignancies.
    Journal of medicinal chemistry, 2017, 02-23, Volume: 60, Issue:4

    Topics: Animals; Antineoplastic Agents; Autophagy; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Glycosides; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Mice, Nude; Myelodysplastic Syndromes; Triazoles; Tumor Cells, Cultured

2017
Carboxyamidotriazole inhibits cell growth of imatinib-resistant chronic myeloid leukaemia cells including T315I Bcr-Abl mutant by a redox-mediated mechanism.
    Cancer letters, 2011, Jan-28, Volume: 300, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mutation; Oxidation-Reduction; Piperazines; Pyrimidines; Reactive Oxygen Species; Triazoles

2011
Ultrasound-assisted one-pot synthesis of anti-CML nucleosides featuring 1,2,3-triazole nucleobase under iron-copper catalysis.
    Ultrasonics sonochemistry, 2012, Volume: 19, Issue:6

    Topics: Catalysis; Copper; Iron; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Structure; Nucleosides; Sonication; Triazoles

2012
Carboxyamidotriazole-orotate inhibits the growth of imatinib-resistant chronic myeloid leukaemia cells and modulates exosomes-stimulated angiogenesis.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Animals; Antineoplastic Agents; Benzamides; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Exosomes; Extracellular Signal-Regulated MAP Kinases; Fusion Proteins, bcr-abl; Gene Expression Regulation, Leukemic; Human Umbilical Vein Endothelial Cells; Humans; Imatinib Mesylate; Interleukin-8; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mice; Neovascularization, Pathologic; Orotic Acid; Phosphorylation; Phosphotyrosine; Piperazines; Proto-Oncogene Proteins c-akt; Pyrimidines; RNA, Messenger; Triazoles; Xenograft Model Antitumor Assays

2012
Breakthrough pulmonary Aspergillus fumigatus infection with multiple triazole resistance in a Spanish patient with chronic myeloid leukemia.
    Revista iberoamericana de micologia, 2013, Jan-03, Volume: 30, Issue:1

    Topics: Adult; Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Aspergillus fumigatus; Caspofungin; Combined Modality Therapy; Cytochrome P-450 Enzyme System; Drug Resistance, Multiple, Fungal; Echinocandins; Fatal Outcome; Female; Fungal Proteins; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Immunosuppressive Agents; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lipopeptides; Point Mutation; Postoperative Complications; Pulmonary Aspergillosis; Recurrence; Spain; Species Specificity; Transplantation Conditioning; Transplantation, Homologous; Triazoles

2013
Lung infection due to opportunistic fungus, Phialemonium obovatum, in a bone marrow transplant recipient: an emerging infection with fungemia and Crohn disease-like involvement of the gastrointestinal tract.
    Annals of diagnostic pathology, 2005, Volume: 9, Issue:4

    Topics: Amphotericin B; Antifungal Agents; Ascomycota; Bone Marrow Transplantation; Drug Resistance, Fungal; Fungemia; Gastrointestinal Diseases; Graft vs Host Disease; Granuloma; Humans; Immunocompromised Host; Itraconazole; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lung Diseases, Fungal; Male; Middle Aged; Opportunistic Infections; Pyrimidines; Triazoles; Voriconazole

2005
Severe pustular eruption associated with imatinib and voriconazole in a patient with chronic myeloid leukemia.
    Dermatology (Basel, Switzerland), 2005, Volume: 211, Issue:4

    Topics: Adult; Antifungal Agents; Antineoplastic Agents; Aspergillosis; Benzamides; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Drug Eruptions; Drug Interactions; Enzyme Inhibitors; Exanthema; Humans; Imatinib Mesylate; Irritants; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lung Diseases, Fungal; Male; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Triazoles; Voriconazole

2005
Effects of carboxyamidotriazole on in vitro models of imatinib-resistant chronic myeloid leukemia.
    Journal of cellular physiology, 2008, Volume: 215, Issue:1

    Topics: Apoptosis; Benzamides; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; In Situ Hybridization, Fluorescence; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; MAP Kinase Signaling System; Molecular Probes; Phosphotyrosine; Piperazines; Pyrimidines; ras Proteins; Triazoles

2008