Page last updated: 2024-08-24

triazoles and Experimental Neoplasms

triazoles has been researched along with Experimental Neoplasms in 69 studies

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-199027 (39.13)18.7374
1990's4 (5.80)18.2507
2000's8 (11.59)29.6817
2010's27 (39.13)24.3611
2020's3 (4.35)2.80

Authors

AuthorsStudies
Cai, KY; He, XH; Li, ZW; Liu, KQ; Sun, XY; Wang, X; Zhao, YC; Zhi, TX1
Hu, R; Liu, ZH; Shi, YJ; Wang, NY; Wang, WL; Xiao, KJ; Xu, Y; Yu, LT; Zhu, YX; Zuo, WQ1
Bugide, S; Green, MR; Gupta, R; Wajapeyee, N1
Gu, LQ; Hu, MH; Huang, ZS; Kuang, GT; Lin, SL; Ou, TM; Peng, W; Su, XX; Tan, JH; Wang, H; Wang, SK; Zeng, DY; Zhang, Q1
Caretti, G; Costelli, P; Dae Ko, K; Fenizia, C; Filippakopoulos, P; Fittipaldi, R; Hatakeyama, S; Merigliano, S; Pierobon, ES; Pin, F; Sandri, M; Sartorelli, V; Sartori, R; Segatto, M; Sperti, C; Zanchettin, G; Zare, H1
Jia, Y; Jian, W; Jin, H; Lin, R; Si, L; Yang, S; Yu, Q1
Chelvanambi, M; Fabian, KPL; Hong, CS; Lang, S; Ludwig, S; Razzo, BM; Storkus, WJ; Whiteside, TL1
Cobb, MH; Ding, Q; Hu, R; Huffman, KE; Johnson, JE; Minna, JD; Savage, TK; Wang, XD; Williams, N; Yu, Y1
Jiang, CS; Li, H; Li, YP; Lu, SM; Wang, XM; Xu, J; Yang, GD; Zhang, SQ1
Beavis, PA; Chow, MT; Darcy, PK; Devaud, C; Divisekera, U; Dwyer, K; John, LB; Paget, C; Smyth, MJ; Stagg, J1
Duan, YC; Li, JF; Liu, HM; Lv, WL; Ma, JL; Mobley, D; Wang, JW; Wang, MM; Wang, ZR; Xu, RM; Ye, XW; Zhao, W; Zheng, YC; Zhu, S; Zhu, YY; Zi, X1
Bejot, R; Goggi, J; Moonshi, SS; Robins, EG1
Bradner, JE; Castillo-Martin, M; Cho, H; Cordon-Cardo, C; Herzka, T; Qi, J; Robinson, BD; Trotman, LC; Wilkinson, JE; Zheng, W1
Currie, RA; Goetz, AK; Goodman, JI; Omiecinski, CJ; Peffer, RC1
Atwood, SX; Balansay, B; Bandopadhayay, P; Bergthold, G; Beroukhim, R; Bradner, JE; Chen, S; Cheshier, SH; Cho, YJ; Gholamin, S; Lee, A; Link, BA; Masoud, S; Mitra, S; Monje, M; Nguyen, B; Oh, S; Oro, AE; Ponnuswami, A; Qi, J; Schubert, S; Tang, JY; Tang, Y; Vue, N; Wechsler-Reya, R; Whitson, RJ; Willardson, MI; Woo, P; Yu, F1
Chen, LK; Chen, WQ; Chen, ZS; Fu, LW; Huang, ZC; Talele, TT; Tang, SJ; To, KK; Wang, F; Wang, XK; Zhang, YK1
Li, H; Sun, Y; Xu, F1
Annamalai, P; Gavara, G; Hiriyan, J; Natesan, S; Sambasivam, G; Shivarudraiah, P; Sukumaran, SK1
Albert, ML; Barreira da Silva, R; Fiette, L; Ingersoll, MA; Laird, ME; Yatim, N1
Chaimovitz, C; Douvdevani, A; Eini, H; Frishman, V; Kachko, L; Lewis, EC; Yulzari, R1
Attiyeh, EF; Carol, H; Gorlick, R; Houghton, PJ; Kang, MH; Keir, ST; Kolb, EA; Kurmasheva, RT; Landesman, Y; Lock, R; Lyalin, D; Maris, JM; Reynolds, CP; Shacham, S; Smith, MA; Wu, J1
Ahn, HY; Chung, KH; Kim, HR; Oh, SM; Park, YJ1
Althaf Hussain, SK; Kumara Swamy, B; Narsimha, S; Satheesh Kumar, N; Srinivasa Rao, M; Vasudeva Reddy, N1
Bradner, JE; DeAngelo, SL; Dhe-Paganon, S; Paulk, J; Roberts, JM; Scott, TG; Seo, HS; Souza, A; Tanaka, M1
Atadja, P; Chan, H; Chen, Z; Chuai, S; Fang, D; Fei, Q; Feng, L; Gao, Y; Ge, H; Ge, X; Gu, J; Huang, Y; Li, E; Li, G; Li, L; Lin, Y; Lingel, A; Liu, Y; Luo, F; Oyang, C; Qi, W; Shi, M; Teng, L; Wang, L; Wang, Y; Wang, Z; Yu, Y; Yu, Z; Zeng, C; Zeng, J; Zhang, C; Zhang, H; Zhang, J; Zhang, L; Zhang, M; Zhang, Q; Zhao, K; Zhao, M; Zhou, S1
Gaballah, K; Hills, A; Oakley, R; Partridge, M; Ryan, A1
Iovanna, JL; Liu, Y; Peng, L; Qu, F; Rocchi, P; Wan, J; Wang, M; Xia, Y1
Arnesano, A; Benvenuti, S; Comoglio, PM; Gentile, A; Lazzari, L; Li Chiavi, G1
Barsoum, J; Bates, RC; Blackman, RK; Foley, KP; Korbut, T; Koya, K; Liu, Y; Proia, DA; Rosenberg, AF; Sang, J; Smith, D; Zhou, D1
Bussink, J; Dubois, LJ; Janssen, MH; Kolb, HC; Lambin, P; Lieuwes, NG; Ollers, MC; Peeters, WJ; van der Kogel, A; van Dongen, GA; Walsh, JC; Windhorst, AD1
Billups, CA; Carol, H; Gorlick, R; Houghton, PJ; Kang, MH; Keir, ST; Kolb, EA; Kurmasheva, RT; Lock, RB; Maris, JM; Reynolds, CP; Smith, MA1
Blanco, JR; Martínez, A; Ochoa-Callejero, L; Oteo, JA; Pérez-Martínez, L; Rubio-Mediavilla, S1
Chiles, J; Kohn, EC; Moody, E; Moody, TW; Sieczkiewicz, GJ1
Checkley, D; Curry, B; Dukes, M; Kendrew, J; Middleton, B; Tessier, JJ; Waterton, JC; Wedge, SR1
Konovalova, NP1
KOHLER, L; NIEPER, HA1
NAPALKOV, NP1
Bruneteau, G; Clement, O; Cuenod, CA; de Bazelaire, C; Frija, G; Frouin, F; Pradel, C; Robert, PH; Siauve, N; Tessier, JL; Wedge, SR1
Balboa, J; Brenlla, J; Freire-Garabal, M; García-Vallejo, LA; Núñez, MJ; Rey-Méndez, M; Rodrigo, E; Suárez, JM1
Cherdyntseva, NV; Choinzonov, EL; Kagiya, TV; Kondakova, IV; Tcheredova, VV; Zagrebelnaya, GV1
Hilgard, P; Peukert, M; Pohl, J1
Boehme, K; Mohr, U; Steinhoff, D; Weber, H1
Fujita, T; Hiasa, Y; Iwata, C; Kitahori, Y; Ohshima, M; Yuasa, T1
Kniazev, DK; Kulagina, TF; Parfenov, IuD; Ryzhova, NI; Savluchinskaia, LA1
Wahab, A1
Feinstein, RN; Fry, RJ; Staffeldt, EF1
Alonso, G; Contreras, A; Sánchez-Pérez, RM1
Hananouchi, M; Hirao, K; Hirose, M; Tatematsu, M; Tsuda, H1
Abe, M; Kagiya, VT; Masuoka, M; Nishimoto, S; Sasai, K; Shibamoto, Y; Sugita, T; Zhou, L1
Abe, M; Ito, T; Kagiya, VT; Nishimoto, S; Sasai, K; Wang, J1
Abe, M; Hisanaga, Y; Kagiya, T; Nishimoto, S; Sasai, K; Shibamoto, Y; Shimokawa, K; Takahashi, M; Wang, J; Zhou, L1
Bieser, W; Fiebig, HH; Henss, H; Lohr, GW; Schmid, JR1
Abe, M; Kagiya, T; Kimura, R; Nishidai, T; Nishimoto, S; Ono, K; Sakano, K; Shibamoto, Y1
Assandri, A; Bassi, L; Filippeschi, S; Galliani, G; Mistrello, G1
Brockman, RW1
Hruban, Z; Morris, HP; Rechcigl, M1
Vasil'eva, NN2
Higashi, T; Kashiwagi, K; Tobe, T1
Tjälve, H1
Doniach, I1
Adamson, RH; Hahn, MA1
Dogen, M; Higashi, T1
Clayton, JD; Shealy, YF1
Cohen, HJ1
Montgomery, JA; Thomas, HJ1
Florvall, L1
Pliss, MB; Rubenchik, BL; Shipko, GP1

Reviews

1 review(s) available for triazoles and Experimental Neoplasms

ArticleYear
Biochemical aspects of drug combinations.
    Cancer chemotherapy reports. Part 2, 1974, Volume: 4, Issue:1

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Bleomycin; Camptothecin; Cell Division; Cytarabine; Deferoxamine; Diamines; DNA, Neoplasm; Doxorubicin; Drug Therapy, Combination; Leukemia L1210; Macromolecular Substances; Mice; Neoplasms; Neoplasms, Experimental; Nitrosourea Compounds; Purine Nucleotides; Ribonucleotide Reductases; Thioguanine; Triazoles

1974

Other Studies

68 other study(ies) available for triazoles and Experimental Neoplasms

ArticleYear
Anti-Lung Cancer Activities of 1,2,3-Triazole Curcumin Derivatives via Regulation of the MAPK/NF-κB/STAT3 Signaling Pathways.
    ChemMedChem, 2022, 02-04, Volume: 17, Issue:3

    Topics: Animals; Antineoplastic Agents; Antioxidants; Biphenyl Compounds; Cell Proliferation; Cell Survival; Cells, Cultured; Curcumin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinases; Molecular Structure; Neoplasms, Experimental; NF-kappa B; Picrates; STAT3 Transcription Factor; Structure-Activity Relationship; Triazoles; Zebrafish

2022
Design, synthesis, and biological evaluation of 4,5-dihydro-[1,2,4]triazolo[4,3-f]pteridine derivatives as novel dual-PLK1/BRD4 inhibitors.
    European journal of medicinal chemistry, 2020, Apr-01, Volume: 191

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Proteins; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Male; Mice; Mice, Inbred NOD; Mice, SCID; Molecular Structure; Neoplasms, Experimental; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Structure-Activity Relationship; Transcription Factors; Triazoles; Tumor Cells, Cultured

2020
EZH2 inhibits NK cell-mediated antitumor immunity by suppressing CXCL10 expression in an HDAC10-dependent manner.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 07-27, Volume: 118, Issue:30

    Topics: Animals; Benzopyrans; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Chemokine CXCL10; Chemokines; Decitabine; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Histone Deacetylases; Humans; Indazoles; Indoles; Killer Cells, Natural; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Phenols; Pyridones; Sulfones; Triazoles

2021
Discovery of Novel 11-Triazole Substituted Benzofuro[3,2-b]quinolone Derivatives as c-myc G-Quadruplex Specific Stabilizers via Click Chemistry.
    Journal of medicinal chemistry, 2017, 07-13, Volume: 60, Issue:13

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Proliferation; Click Chemistry; Dose-Response Relationship, Drug; Down-Regulation; Drug Discovery; Drug Screening Assays, Antitumor; G-Quadruplexes; Humans; Mice; Mice, Nude; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Proto-Oncogene Proteins c-myc; Quinolones; Structure-Activity Relationship; Thermodynamics; Triazoles

2017
Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival.
    Nature communications, 2017, 11-22, Volume: 8, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Azepines; Cachexia; Cell Cycle Proteins; Cell Line, Tumor; Epigenesis, Genetic; Forkhead Box Protein O3; Gene Expression Regulation; Humans; Interleukin-6; Male; Metabolic Networks and Pathways; Mice; Muscle, Skeletal; Muscular Atrophy; Neoplasms, Experimental; Nuclear Proteins; Transcription Factors; Triazoles

2017
Thiophenol-formaldehyde triazole causes apoptosis induction in ovary cancer cells and prevents tumor growth formation in mice model.
    European journal of medicinal chemistry, 2019, Jun-15, Volume: 172

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Formaldehyde; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Ovarian Neoplasms; Phenols; Structure-Activity Relationship; Sulfhydryl Compounds; Triazoles; Tumor Cells, Cultured

2019
Impact of combination immunochemotherapies on progression of 4NQO-induced murine oral squamous cell carcinoma.
    Cancer immunology, immunotherapy : CII, 2019, Volume: 68, Issue:7

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Combined Chemotherapy Protocols; Cancer Vaccines; Cisplatin; Combined Modality Therapy; Female; Immunotherapy; Mice; Mice, Inbred C57BL; Mouth Neoplasms; Neoplasms, Experimental; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome; Triazines; Triazoles; Vaccines, Subunit

2019
Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells.
    Nature communications, 2019, 07-19, Volume: 10, Issue:1

    Topics: Animals; Azepines; Basic Helix-Loop-Helix Transcription Factors; Biomarkers, Tumor; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Insulin-Like Growth Factor Binding Protein 5; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasms, Experimental; Neuroendocrine Tumors; Octamer Transcription Factors; Proteomics; Pyrazoles; Receptor, IGF Type 1; Signal Transduction; Small Cell Lung Carcinoma; Transcription Factors; Triazines; Triazoles

2019
Synthesis and anticancer activity evaluation of a series of [1,2,4]triazolo[1,5-a]pyridinylpyridines in vitro and in vivo.
    European journal of medicinal chemistry, 2013, Volume: 67

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; MCF-7 Cells; Mice; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Pyridines; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured

2013
Blockade of A2A receptors potently suppresses the metastasis of CD73+ tumors.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Sep-03, Volume: 110, Issue:36

    Topics: 5'-Nucleotidase; Adenosine A2 Receptor Antagonists; Animals; Cell Line, Tumor; Cytotoxicity, Immunologic; Flow Cytometry; Granzymes; Humans; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Metastasis; Neoplasms, Experimental; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Triazoles; Xanthines

2013
Triazole-dithiocarbamate based selective lysine specific demethylase 1 (LSD1) inactivators inhibit gastric cancer cell growth, invasion, and migration.
    Journal of medicinal chemistry, 2013, Nov-14, Volume: 56, Issue:21

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Histone Demethylases; Humans; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Neoplasms, Experimental; Stomach Neoplasms; Structure-Activity Relationship; Thiocarbamates; Triazoles

2013
A practical synthesis of [(18) F]FtRGD: an angiogenesis biomarker for PET.
    Journal of labelled compounds & radiopharmaceuticals, 2013, Volume: 56, Issue:2

    Topics: Animals; Ligands; Mice; Neoplasms, Experimental; Neovascularization, Pathologic; Peptides, Cyclic; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution; Triazoles

2013
RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis.
    Cancer discovery, 2014, Volume: 4, Issue:3

    Topics: Animals; Azepines; Gene Expression Regulation, Neoplastic; Genetic Vectors; HEK293 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Metastasis; Neoplasms, Experimental; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; PTEN Phosphohydrolase; Retroviridae; Triazoles; Tumor Suppressor Protein p53

2014
Phenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in their mode of action.
    Toxicology, 2014, Jul-03, Volume: 321

    Topics: Animals; Carcinogenicity Tests; Carcinogens; Cell Proliferation; Constitutive Androstane Receptor; Female; Fungicides, Industrial; Genes, Reporter; Hepatocytes; Hypnotics and Sedatives; Male; Mice; Neoplasms, Experimental; Organ Size; Phenobarbital; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Toxicogenetics; Triazoles; Weight Gain

2014
Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.
    Nature medicine, 2014, Volume: 20, Issue:7

    Topics: Animals; Azepines; Epigenesis, Genetic; Hedgehog Proteins; Kruppel-Like Transcription Factors; Ligands; Mice; Neoplasms, Experimental; Nuclear Proteins; Promoter Regions, Genetic; Signal Transduction; Transcription Factors; Transcription, Genetic; Triazoles; Zinc Finger Protein GLI1; Zinc Finger Protein Gli2

2014
CEP-33779 antagonizes ATP-binding cassette subfamily B member 1 mediated multidrug resistance by inhibiting its transport function.
    Biochemical pharmacology, 2014, Sep-15, Volume: 91, Issue:2

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Heterografts; Humans; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Pyridines; Real-Time Polymerase Chain Reaction; Rhodamine 123; Topotecan; Triazoles

2014
Inhibition of Axl improves the targeted therapy against ALK-mutated neuroblastoma.
    Biochemical and biophysical research communications, 2014, 11-28, Volume: 454, Issue:4

    Topics: Anaplastic Lymphoma Kinase; Animals; Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Crizotinib; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Neuroblastoma; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Pyrazoles; Pyridines; Receptor Protein-Tyrosine Kinases; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured

2014
Discovery of PAT-1102, a novel, potent and orally active histone deacetylase inhibitor with antitumor activity in cancer mouse models.
    Anticancer research, 2015, Volume: 35, Issue:1

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; HCT116 Cells; HeLa Cells; Histone Deacetylase Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Hydroxamic Acids; Inhibitory Concentration 50; Male; Mice, Inbred BALB C; Mice, Nude; Mice, SCID; Neoplasms, Experimental; Neovascularization, Pathologic; Triazoles; Vorinostat; Xenograft Model Antitumor Assays

2015
Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy.
    Nature immunology, 2015, Volume: 16, Issue:8

    Topics: Adoptive Transfer; Animals; Cell Line, Tumor; Cell Movement; Chemokine CXCL10; Chemokines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Female; Flow Cytometry; Immunotherapy; Lymphocytes; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neoplasms, Experimental; Pyrazines; Receptors, CXCR3; Sitagliptin Phosphate; Triazoles

2015
Caffeine promotes anti-tumor immune response during tumor initiation: Involvement of the adenosine A2A receptor.
    Biochemical pharmacology, 2015, Nov-01, Volume: 98, Issue:1

    Topics: Adenosine A2 Receptor Antagonists; Animals; Caffeine; Cell Line, Tumor; Cyclopentanes; Fibrosarcoma; Mice; Mice, Knockout; Neoplasms, Experimental; Receptor, Adenosine A2A; Triazines; Triazoles

2015
Pharmacodynamic and genomic markers associated with response to the XPO1/CRM1 inhibitor selinexor (KPT-330): A report from the pediatric preclinical testing program.
    Pediatric blood & cancer, 2016, Volume: 63, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Exportin 1 Protein; Female; Humans; Hydrazines; Inhibitory Concentration 50; Karyopherins; Mice; Mice, SCID; Neoplasms, Experimental; Receptors, Cytoplasmic and Nuclear; Triazoles; Xenograft Model Antitumor Assays

2016
Ginkgo biloba extract EGb 761-mediated inhibition of aromatase for the treatment of hormone-dependent breast cancer.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2016, Volume: 87

    Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Aromatase; Breast Neoplasms; Cell Proliferation; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Ginkgo biloba; Humans; Mammary Neoplasms, Animal; MCF-7 Cells; Mice; Neoplasms, Experimental; Nitriles; Plant Extracts; RNA, Messenger; Triazoles

2016
Indole-2-carboxylic acid derived mono and bis 1,4-disubstituted 1,2,3-triazoles: Synthesis, characterization and evaluation of anticancer, antibacterial, and DNA-cleavage activities.
    Bioorganic & medicinal chemistry letters, 2016, Mar-15, Volume: 26, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Bacillus subtilis; Carboxylic Acids; Cell Proliferation; DNA Cleavage; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Escherichia coli; HEK293 Cells; HeLa Cells; Humans; Indoles; Male; MCF-7 Cells; Mice; Microbial Sensitivity Tests; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship; Triazoles

2016
Design and characterization of bivalent BET inhibitors.
    Nature chemical biology, 2016, Volume: 12, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Azepines; Cell Cycle Proteins; Cell Proliferation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Humans; Leukemia; Ligands; Mice; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Nuclear Proteins; Small Molecule Libraries; Structure-Activity Relationship; Transcription Factors; Triazoles

2016
An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED.
    Nature chemical biology, 2017, Volume: 13, Issue:4

    Topics: Allosteric Regulation; Animals; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Histones; Humans; Lysine; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Polycomb Repressive Complex 2; Structure-Activity Relationship; Sulfones; Triazoles; Tumor Cells, Cultured

2017
The antiangiogenic agent ZD4190 prevents tumour outgrowth in a model of minimal residual carcinoma in deep tissues.
    British journal of cancer, 2009, Aug-04, Volume: 101, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Disease Models, Animal; Female; Mice; Mice, Inbred C57BL; Neoplasm, Residual; Neoplasms, Experimental; Quinazolines; Triazoles; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2009
Novel triazole ribonucleoside down-regulates heat shock protein 27 and induces potent anticancer activity on drug-resistant pancreatic cancer.
    Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19

    Topics: Animals; Apoptosis; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; HSP27 Heat-Shock Proteins; Humans; Mice; Neoplasms, Experimental; Pancreatic Neoplasms; Ribonucleosides; Transplantation, Heterologous; Treatment Outcome; Triazoles

2009
Ron kinase transphosphorylation sustains MET oncogene addiction.
    Cancer research, 2011, Mar-01, Volume: 71, Issue:5

    Topics: Animals; Blotting, Western; Cell Line, Tumor; Female; Gene Silencing; Humans; Mice; Mice, Nude; Neoplasms, Experimental; Oncogenes; Phosphorylation; Proto-Oncogene Proteins c-met; Pyrazoles; Pyridazines; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Signal Transduction; Transcriptional Activation; Transplantation, Heterologous; Triazoles

2011
Multifaceted intervention by the Hsp90 inhibitor ganetespib (STA-9090) in cancer cells with activated JAK/STAT signaling.
    PloS one, 2011, Apr-14, Volume: 6, Issue:4

    Topics: Animals; Cell Division; Genes, cdc; HSP90 Heat-Shock Proteins; Janus Kinase 2; Mice; Neoplasms, Experimental; Signal Transduction; STAT Transcription Factors; Triazoles; Tumor Cells, Cultured

2011
Preclinical evaluation and validation of [18F]HX4, a promising hypoxia marker for PET imaging.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Aug-30, Volume: 108, Issue:35

    Topics: Animals; Biomarkers; Cell Hypoxia; Fluorine Radioisotopes; Imidazoles; Male; Neoplasms, Experimental; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Triazoles

2011
Initial testing (stage 1) of ganetespib, an Hsp90 inhibitor, by the Pediatric Preclinical Testing Program.
    Pediatric blood & cancer, 2013, Volume: 60, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; HSP90 Heat-Shock Proteins; Humans; Mice; Mice, SCID; Neoplasms, Experimental; Triazoles; Xenograft Model Antitumor Assays

2013
Maraviroc, a CCR5 antagonist, prevents development of hepatocellular carcinoma in a mouse model.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; CCR5 Receptor Antagonists; Cell Proliferation; Cyclohexanes; Humans; Liver Cirrhosis; MAP Kinase Signaling System; Maraviroc; Mice; Neoplasms, Experimental; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Receptors, CCR5; Triazoles

2013
CAI inhibits the growth of small cell lung cancer cells.
    Lung cancer (Amsterdam, Netherlands), 2003, Volume: 39, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma, Small Cell; Cell Division; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasms, Experimental; Neovascularization, Pathologic; Transplantation, Heterologous; Triazoles; Tumor Cells, Cultured

2003
Dynamic contrast-enhanced MRI of vascular changes induced by the VEGF-signalling inhibitor ZD4190 in human tumour xenografts.
    Magnetic resonance imaging, 2003, Volume: 21, Issue:5

    Topics: Animals; Contrast Media; Female; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Quinazolines; Transplantation, Heterologous; Triazoles; Vascular Endothelial Growth Factor A

2003
Ultralow doses of various drugs in chemotherapy of experimental tumors.
    Bulletin of experimental biology and medicine, 2003, Volume: 135 Suppl 7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Indazoles; Leukemia P388; Lung Neoplasms; Melanoma; Mice; Mitomycin; Neoplasm Metastasis; Neoplasms, Experimental; Triazoles; Xenograft Model Antitumor Assays

2003
[The development and evaluation of fungistatic compounds in the treatment of cancer. 2].
    Arztliche Forschung, 1963, Apr-10, Volume: 17

    Topics: Antifungal Agents; Antineoplastic Agents; Humans; Neoplasms; Neoplasms, Experimental; Triazoles

1963
ON SOME NEW ASPECTS OF EXPERIMENTAL CARCINOGENESIS THYROID GLAND.
    Acta - Unio Internationalis Contra Cancrum, 1963, Volume: 19

    Topics: Carcinogenesis; Methylthiouracil; Neoplasms; Neoplasms, Experimental; Rats; Research; Thyroid Neoplasms; Triazoles

1963
Reduced capillary perfusion and permeability in human tumour xenografts treated with the VEGF signalling inhibitor ZD4190: an in vivo assessment using dynamic MR imaging and macromolecular contrast media.
    Magnetic resonance imaging, 2003, Volume: 21, Issue:8

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Capillary Permeability; Cell Line, Tumor; Contrast Media; Magnetic Resonance Angiography; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Neovascularization, Pathologic; Quinazolines; Triazoles; Vascular Endothelial Growth Factor A

2003
Effects of nefazodone on the development of experimentally induced tumors in stressed rodents.
    Psychopharmacology, 2004, Volume: 176, Issue:3-4

    Topics: Animals; Antidepressive Agents, Second-Generation; Carcinoma 256, Walker; Male; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Piperazines; Rats; Rats, Sprague-Dawley; Retroviridae Infections; Stress, Psychological; Triazoles; Tumor Cells, Cultured; Tumor Virus Infections

2004
Production of nitric oxide by hypoxic radiosensitizer sanazole.
    Experimental oncology, 2004, Volume: 26, Issue:4

    Topics: Animals; Cell Hypoxia; Lymphoma; Mastocytoma; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Nitric Oxide; Oxyhemoglobins; Radiation-Sensitizing Agents; Triazoles

2004
alpha-/beta-Triglycidyl-urazol (TGU, NSC 332488, I.N.N.: ANAXIRONE): a new chemotherapeutic agent.
    Cancer treatment reviews, 1984, Volume: 11, Issue:2

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Drug Evaluation; Drug Evaluation, Preclinical; Humans; Kinetics; Metabolic Clearance Rate; Mice; Neoplasms; Neoplasms, Experimental; Rats; Triazines; Triazoles

1984
Evaluation of amitrole (aminotriazole) for potential carcinogenicity in orally dosed rats, mice, and golden hamsters.
    Toxicology and applied pharmacology, 1983, Jun-30, Volume: 69, Issue:2

    Topics: Amitrole; Animals; Carcinogens; Cricetinae; Female; Iodine Radioisotopes; Liver Neoplasms; Male; Mesocricetus; Mice; Neoplasms, Experimental; Organ Size; Pituitary Neoplasms; Rats; Rats, Inbred Strains; Thyroid Gland; Thyroid Neoplasms; Triazoles

1983
Promoting effects of 3-amino-1,2,4-triazole on the development of thyroid tumors in rats treated with N-bis(2-hydroxypropyl)nitrosamine.
    Carcinogenesis, 1982, Volume: 3, Issue:4

    Topics: Amitrole; Animals; Carcinogens; Drug Synergism; Male; Neoplasms, Experimental; Nitrosamines; Organ Size; Rats; Rats, Inbred Strains; Thyroid Gland; Thyroid Neoplasms; Triazoles

1982
[Study of cancerogenic effect of 4-amino-1,2,4-triazole in chronic experiments].
    Gigiena i sanitariia, 1993, Issue:11

    Topics: Administration, Oral; Animals; Female; Incidence; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Neoplasms, Experimental; Rats; Rats, Wistar; Sex Factors; Triazoles

1993
Clinical development plan: (+)-vorozole.
    Journal of cellular biochemistry. Supplement, 1996, Volume: 26

    Topics: Animals; Anticarcinogenic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Drug Approval; Enzyme Inhibitors; Estradiol; Female; Humans; Male; Neoplasms, Experimental; Rats; Research Design; Triazoles

1996
Substituted thiatriazoles as possible anticancer compounds.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:5

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Humans; Neoplasms, Experimental; Triazoles

1979
Carcinogenic and antitumor effects of aminotriazole on acatalasemic and normal catalase mice.
    Journal of the National Cancer Institute, 1978, Volume: 60, Issue:5

    Topics: Amitrole; Animals; Antineoplastic Agents; Carcinogens; Catalase; Female; Liver Neoplasms; Lymphoma; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Triazoles

1978
Halomethyl-1,2,3-triazole derivatives: a new type of alkylating agent active in mouse transplantable tumors.
    Cancer chemotherapy and pharmacology, 1978, Volume: 1, Issue:4

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Cells, Cultured; DNA, Neoplasm; Drug Stability; Female; Mice; Mice, Inbred ICR; Neoplasm Transplantation; Neoplasms, Experimental; Time Factors; Transplantation, Homologous; Triazoles

1978
Tumorigenic effect of 3-amino-1H-1,2,4-triazole on rat thyroid.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:4

    Topics: Amitrole; Animals; Cystadenoma; Female; Goiter; Hyperplasia; Neoplasms, Experimental; Rats; Thyroid Gland; Thyroid Neoplasms; Transplantation, Autologous; Triazoles

1976
Metabolic rate modification of nitrotriazole radiosensitizers by sulfur substitution of side chain.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3

    Topics: Animals; Cell Hypoxia; Combined Modality Therapy; Female; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Radiation-Sensitizing Agents; Triazoles; Tumor Cells, Cultured

1992
Fluorine modification of nitroazole radiosensitizers for the enhancement of sensitizing activity with lowering toxicity: a pharmacokinetic characterization.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3

    Topics: Animals; Brain; Combined Modality Therapy; Female; Lethal Dose 50; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Triazoles

1992
Characteristics of fluorinated nitroazoles as hypoxic cell radiosensitizers.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:4

    Topics: Animals; Cell Survival; Combined Modality Therapy; Hydrocarbons, Fluorinated; In Vitro Techniques; Lethal Dose 50; Mice; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Triazoles

1989
Colony assay with human tumor xenografts, murine tumors and human bone marrow. Potential for anticancer drug development.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:7

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Cell Division; Cell Survival; Cells, Cultured; Colony-Forming Units Assay; Dose-Response Relationship, Drug; In Vitro Techniques; Mice; Mice, Nude; Neoplasms, Experimental; Ribavirin; Transplantation, Heterologous; Triazoles

1987
Radiosensitization in vitro and in vivo by 3-nitrotriazoles.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7

    Topics: Animals; Combined Modality Therapy; Cricetinae; Female; In Vitro Techniques; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitro Compounds; Nitroimidazoles; Radiation-Sensitizing Agents; Triazoles

1986
Immunological profile of DL111-IT, a new immunosuppressant agent.
    Immunopharmacology, 1985, Volume: 10, Issue:3

    Topics: Animals; Antibody Formation; Dose-Response Relationship, Drug; Hypersensitivity, Delayed; Immunosuppressive Agents; Inflammation; Lymphoma; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Triazoles

1985
The roles of synthesis and degradation in the regulation of catalase levels in the neoplastic tissues.
    Enzymologia biologica et clinica, 1969, Volume: 10, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Catalase; Cell Membrane Permeability; Hydrogen; Kinetics; Liver; Liver Neoplasms; Mice; Microscopy, Electron; Neoplasms, Experimental; Peroxidases; Triazoles

1969
[Morphologic characteristics of spontaneous tumors and leukoses in 1st generation C47B1XCBA hybrid mice].
    Voprosy onkologii, 1969, Volume: 15, Issue:8

    Topics: Adenoma; Animals; Carcinogens; Carcinoma, Hepatocellular; Leukemia, Experimental; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Mice; Neoplasms, Experimental; Triazoles

1969
Studies on rat liver catalase. V. Incorporation of 14 C-leucine into catalase by isolated rat liver ribosomes.
    Journal of biochemistry, 1971, Volume: 70, Issue:5

    Topics: Acetamides; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Catalase; Cell-Free System; Cycloheximide; Dactinomycin; Depression, Chemical; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Nucleotides; Puromycin; Rats; Ribonucleases; Ribosomes; Triazoles

1971
X-accumulation of labelled aminotriazole in some transplanted tumours in mice.
    British journal of cancer, 1974, Volume: 30, Issue:2

    Topics: Animals; Autoradiography; Carbon Radioisotopes; Carcinoma; Fibrosarcoma; Intestines; Kidney; Liver; Lymphoma; Mammary Neoplasms, Experimental; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Spleen; Time Factors; Transplantation, Homologous; Triazoles

1974
Carcinogenic effect of 100, 250 and 500 rad X-rays on the rat thyroid gland.
    British journal of cancer, 1974, Volume: 30, Issue:6

    Topics: Adenocarcinoma; Adenoma; Animals; Male; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Radiation Dosage; Rats; Rats, Inbred Strains; Thyroid Neoplasms; Thyrotropin; Thyroxine; Triazoles

1974
Pharmacology of 3,5-diamino-1,24-triazole (guanazole). 1. Antitumor activity of guanazole.
    Journal of the National Cancer Institute, 1972, Volume: 48, Issue:3

    Topics: Amines; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cyclophosphamide; Cytarabine; Depression, Chemical; Female; Hydroxyurea; In Vitro Techniques; Leukemia L1210; Leukemia, Experimental; Lymphoma, Large B-Cell, Diffuse; Male; Mast-Cell Sarcoma; Methotrexate; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Plasmacytoma; Structure-Activity Relationship; Triazoles

1972
[Differences among liver, kidney and erythrocyte catalasses of the rat].
    Seikagaku. The Journal of Japanese Biochemical Society, 1972, Volume: 44, Issue:12

    Topics: Allyl Compounds; Animals; Antigen-Antibody Reactions; Catalase; Electrophoresis; Enzyme Activation; Erythrocytes; Kidney; Kinetics; Liver; Male; Neoplasms, Experimental; Rats; Triazoles

1972
Carbocyclic analog of purine ribonucleosides with antileukemic activity.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:5

    Topics: Aza Compounds; Carcinoma, Squamous Cell; Cells, Cultured; Humans; Leukemia; Neoplasms, Experimental; Purines; Ribonucleosides; Triazoles

1973
Peroxide detoxification affecting the production of immunoglobulin by mouse myeloma tumor cells in vitro.
    Experientia, 1973, Oct-15, Volume: 29, Issue:10

    Topics: Animals; Catalase; Cells, Cultured; Glucose; Immunoglobulins; Leucine; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Peroxidases; Peroxides; Plasmacytoma; Stimulation, Chemical; Triazoles; Tritium

1973
Nucleosides of 8-azapurines (v-triazolo(4,5-d) pyrimidines).
    Journal of medicinal chemistry, 1972, Volume: 15, Issue:3

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cells, Cultured; Deamination; Humans; Magnetic Resonance Spectroscopy; Neoplasms, Experimental; Nucleosides; Optical Rotation; Pyrimidines; Stereoisomerism; Structure-Activity Relationship; Triazoles

1972
Some antitumor agents derived from benzaldehyde nitrogen mustards.
    Acta pharmaceutica Suecica, 1970, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Chemical Phenomena; Chemistry; Hydrazines; Leukemia L1210; Mice; Neoplasms, Experimental; Nitrogen Mustard Compounds; Rats; Triazoles

1970
[A comparative evaluation of the toxic and possible carcinogenic effect of benzotriazol and phenidon].
    Gigiena truda i professional'nye zabolevaniia, 1970, Volume: 14, Issue:3

    Topics: Animals; Carcinogens; Chemical and Drug Induced Liver Injury; Female; Fibroma; Leukemia, Experimental; Lung Diseases; Lung Neoplasms; Male; Mesentery; Mice; Neoplasms, Experimental; Rats; Sarcoma, Experimental; Splenic Diseases; Triazoles

1970
[Water-soluble and lipid-bound catalase in the liver and malignant tumors of rats].
    Ukrains'kyi biokhimichnyi zhurnal, 1966, Volume: 38, Issue:3

    Topics: Animals; Carcinoma; Catalase; Chemical Phenomena; Chemistry, Physical; Depression, Chemical; Lipid Metabolism; Liver; Neoplasms, Experimental; Rats; Sarcoma, Experimental; Solubility; Triazoles

1966