triazoles has been researched along with Experimental Mammary Neoplasms in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.17) | 18.7374 |
| 1990's | 19 (39.58) | 18.2507 |
| 2000's | 14 (29.17) | 29.6817 |
| 2010's | 13 (27.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bode, A; Grubbs, CJ; Juliana, MM; Lubet, RA; Moeinpour, F; Steele, VE | 1 |
| Huang, L; Huang, Y; Huang, Z; Jiang, Y; Liao, Y; Shen, Y; Sun, X; Wei, G; Xu, X; Zhao, C | 1 |
| Bode, AM; Ghazoui, Z; Grubbs, CJ; Liu, P; Lu, Y; Lubet, RA; Vedell, PT; Wen, W; You, M | 1 |
| Kang, XM; Ma, WJ; Song, Y; Wang, L; Zhang, QY; Zhao, H | 1 |
| Ajay, A; Bhattacharjee, A; Bora, HK; Das, S; Devender, N; Dwivedi, S; Gupt, MP; Konwar, R; Mitra, K; Saini, KS; Tripathi, RP | 1 |
| Bainer, R; Becker, L; Chada, K; Frankenberger, C; Gilad, Y; Krausz, T; Rabe, D; Rosner, MR; Sankarasharma, D | 1 |
| Alizadeh, AM; Amani Shalamzari, S; Isanejad, A; Khodayari, H; Khodayari, S; Khojastehnjad, N; Khori, V | 1 |
| Belosay, A; Churchwell, MI; Doerge, DR; Hartman, JA; Helferich, WG; Iwaniec, UT; Song, H; Turner, RT; Wang, W; Yang, X | 1 |
| Fu, L; Gu, Y; Jiang, J; Li, L; Li, Z; Liu, J; Lu, Y; Niu, D; Xia, F; Xu, W; Zhou, Z | 1 |
| Adamicova, K; Kajo, K; Kubatka, P; Nosalova, G; Ostatnikova, D; Sadlonova, J; Sadlonova, V | 1 |
| Chen, Y; Gonzalez-Angulo, A; Guggisberg, N; Hennessy, B; Jorda, M; Mills, GB; Slingerland, JM; Tan, CK | 1 |
| Bocchinfuso, W; Conaway, M; Fan, P; Korach, KS; Li, Y; Liu, G; Santen, R; Wang, H; Wang, JP; Yue, W; Zhang, N | 1 |
| A'Hern, R; Banerjee, S; Detre, S; Dowsett, M; Evans, DB; Littlewood-Evans, AJ; Martin, LA | 1 |
| Albertelli, MA; Feldman, D; Jensen, K; Krishnan, AV; Peng, L; Swami, S; Wang, JY | 1 |
| Brodie, A; Carboni, JM; Finckenstein, FG; Gottardis, MM; Greer, A; Haluska, P; Harrington, SC; Hou, X; Huang, F; Macedo, LF; Reeves, KA | 1 |
| Brodie, AM; Jelovac, D; Long, BJ; Thiantanawat, A | 1 |
| Brodie, AH; Jelovac, D; Long, B | 1 |
| Jones, J; Kirma, N; Luthra, R; Tekmal, RR | 1 |
| Brodie, A; Goloubeva, O; Jelovac, D; Macedo, L; Sabnis, G; Tilghman, S | 1 |
| Fetisovova, Z; Kajo, K; Kubatka, P; Nosalova, G; Sadlonova, V | 1 |
| Bode, AM; Christov, K; Ericson, ME; Grubbs, CJ; Juliana, MM; Lubet, RA; Steele, VE; Szabo, E | 1 |
| Brodie, A; Savinov, A; Wang, J; Yue, W | 1 |
| Lohmeyer, M; Workman, P | 1 |
| De Coster, R; Snoeck, E; Wouters, W | 1 |
| Ara, G; Chen, YN; Holden, SA; Korbut, TT; Northey, D; Teicher, BA | 1 |
| Casebolt, TL; Eto, I; Grubbs, CJ; Kelloff, GJ; Lubet, RA; Steele, VE | 1 |
| Batzl, C; Bhatnagar, AS; Lang, M; Schieweck, K | 1 |
| Callens, M; De Coster, R; Goeminne, N; Janssens, B; Van Ginckel, R; Wouters, L | 1 |
| Durgam, VR; Tekmal, RR | 1 |
| Fingar, VH; Halling, BP; Haydon, PS; McMahon, KS; Wieman, TJ; Winkelman, JW; Yuhas, DA | 1 |
| Dukes, M | 1 |
| Brodie, A; Liu, Y; Long, B; Lu, Q; Wang, JP; Yue, W | 1 |
| Bowden, C; DeCoster, R; Eto, I; Grubbs, CJ; Juliana, MM; Kelloff, GJ; Lubet, RA; Steele, VE; You, M | 1 |
| Brodie, A; Liu, Y; Long, B; Lu, Q; Wang, J; Yue, W | 1 |
| Iino, Y; Koibuchi, Y; Morishita, Y; Sugamata, N | 1 |
| Brodie, A; Gimbel, M; Grigoryev, D; Liu, Y; Long, BJ; Lu, Q | 1 |
| Fowler, K; Gill, K; Kirma, N; Tekmal, RR | 1 |
| Christov, K; Green, A; Grubbs, C; Kelloff, G; Lubet, R; Mehta, RG; Shilkaitis, A | 1 |
| Kothari, L; Murugesan, S; Nair, CK; Noronha, OP; Samuel, AM; Shetty, SJ; Srivastava, TS | 1 |
| Crist, KA; Grubbs, CJ; Hu, L; Johanning, GL; Lubet, RA; Wang, M; Wang, Y; Yao, R; You, M | 1 |
| Knott, KK; Lubet, RA; McGinley, JN; Steele, VE; Thompson, HJ | 1 |
| Kirma, N; Mandava, U; Tekmal, RR | 1 |
| Blankenstein, MA; Blijham, GH; Brodie, AM; Chen, T; DeJong, PC; Elbers, JR; Fulton, A; Long, BJ; Lu, Q; Macpherson, N; Nortier, JW; Schipper, ME; Slee, PH; Thijssen, JH; van de Ven, J; van Gorp, JM | 1 |
| Feinstein, RN; Fry, RJ; Staffeldt, EF | 1 |
| Callens, MJ; De Coster, R; Goeminne, NK; Janssens, BL; Van Ginckel, RF | 1 |
| Byloos, M; De Coster, R; Goeminne, N; Van Ginckel, R; Vanherck, W; Wouters, W | 1 |
| Bhatnagar, AS; Bowman, R; Häusler, A; Lang, M; Schieweck, K | 1 |
| Tjälve, H | 1 |
4 review(s) available for triazoles and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
Therapeutic observations in MCF-7 aromatase xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase; Aromatase Inhibitors; Disease Models, Animal; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Letrozole; Mammary Neoplasms, Experimental; Mice; Nitriles; Receptors, Estrogen; Triazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2005 |
Vorozole, a specific non-steroidal aromatase inhibitor.
Topics: Animals; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estradiol; Female; Hormones; Humans; In Vitro Techniques; Male; Mammary Neoplasms, Experimental; Triazoles | 1994 |
The relevance of preclinical models to the treatment of postmenopausal breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anastrozole; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Mammary Neoplasms, Experimental; Nitriles; Postmenopause; Rats; Triazoles | 1997 |
Highly selective inhibition of estrogen biosynthesis by CGS 20267, a new non-steroidal aromatase inhibitor.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aromatase Inhibitors; Estrogen Antagonists; Estrogens; Fadrozole; Imidazoles; Letrozole; Mammary Neoplasms, Experimental; Nitriles; Steroids; Triazoles | 1990 |
44 other study(ies) available for triazoles and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
Daily or weekly dosing with EGFR inhibitors, gefitinib and lapatinib, and AKt inhibitor MK2206 in mammary cancer models.
Topics: Animals; Disease Models, Animal; Drug Administration Schedule; ErbB Receptors; Female; Gefitinib; Heterocyclic Compounds, 3-Ring; Lapatinib; Male; Mammary Neoplasms, Experimental; Mice; Mice, Knockout; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; Triazoles | 2018 |
A tumor-targeted Ganetespib-zinc phthalocyanine conjugate for synergistic chemo-photodynamic therapy.
Topics: Animals; Breast Neoplasms; Cell Line; Cell Line, Tumor; Drug Delivery Systems; Drug Synergism; Female; HSP90 Heat-Shock Proteins; Humans; Indoles; Isoindoles; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organometallic Compounds; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species; Triazoles; Zinc Compounds | 2018 |
Concordant effects of aromatase inhibitors on gene expression in ER+ Rat and human mammary cancers and modulation of the proteins coded by these genes.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Nitriles; Oligonucleotide Array Sequence Analysis; Rats; Real-Time Polymerase Chain Reaction; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triazoles | 2013 |
[Effect of genistein combined with anastrozole on mammary tumors in ovariectomized rats].
Topics: 17-Hydroxysteroid Dehydrogenases; Anastrozole; Animals; Cell Line, Tumor; Cell Proliferation; Estradiol; Female; Genistein; Mammary Neoplasms, Experimental; Nitriles; Ovariectomy; Postmenopause; Rats; Rats, Sprague-Dawley; Triazoles | 2014 |
Triazole analog 1-(1-benzyl-5-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)-2-(4-bromophenylamino)-1-(4-chlorophenyl)ethanol induces reactive oxygen species and autophagy-dependent apoptosis in both in vitro and in vivo breast cancer models.
Topics: Animals; Apoptosis; Autophagy; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Ethanol; Female; HEK293 Cells; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Triazoles | 2015 |
Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages.
Topics: Animals; Cell Line, Tumor; Chemokine CCL5; Chemokines; Chemotaxis; Cyclohexanes; Disease-Free Survival; Female; Gene Expression Profiling; Gene Knockdown Techniques; Heterografts; HMGA2 Protein; Humans; Macrophages; Mammary Neoplasms, Experimental; Maraviroc; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Neoplasm Metastasis; Neoplasm Proteins; Phosphatidylethanolamine Binding Protein; Receptors, CCR5; RNA, Messenger; RNA, Neoplasm; Sequence Analysis, RNA; Triazoles; Triple Negative Breast Neoplasms; Tumor Microenvironment | 2015 |
MicroRNA-206, let-7a and microRNA-21 pathways involved in the anti-angiogenesis effects of the interval exercise training and hormone therapy in breast cancer.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Combined Modality Therapy; Exercise Therapy; Female; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; MicroRNAs; Muscle, Skeletal; Neovascularization, Pathologic; Nitriles; Signal Transduction; Tamoxifen; Triazoles | 2016 |
Effects of letrozole on breast cancer micro-metastatic tumor growth in bone and lung in mice inoculated with murine 4T1 cells.
Topics: Animals; Aromatase Inhibitors; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Letrozole; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Neoplasm Micrometastasis; Nitriles; Triazoles | 2016 |
Ganetespib overcomes resistance to PARP inhibitors in breast cancer by targeting core proteins in the DNA repair machinery.
Topics: Animals; Antineoplastic Agents; Benzimidazoles; BRCA1 Protein; BRCA2 Protein; Cell Line, Tumor; DNA Repair; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Female; HSP90 Heat-Shock Proteins; Humans; Mammary Neoplasms, Experimental; Mice, SCID; Poly(ADP-ribose) Polymerase Inhibitors; Rad51 Recombinase; Radiation, Ionizing; Triazoles; Tumor Burden | 2017 |
Side effects of anastrozole in the experimental pre-menopausal mammary carcinogenesis.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitriles; Rats; Rats, Sprague-Dawley; Triazoles; Uterus; Vagina | 2009 |
Combined Src and aromatase inhibition impairs human breast cancer growth in vivo and bypass pathways are activated in AZD0530-resistant tumors.
Topics: Anastrozole; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Benzodioxoles; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; CSK Tyrosine-Protein Kinase; Cyclin-Dependent Kinase Inhibitor p27; Drug Resistance, Neoplasm; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinases; Nitriles; Phosphatidylinositol 3-Kinases; Protein-Tyrosine Kinases; Quinazolines; Signal Transduction; src-Family Kinases; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays | 2009 |
Effects of estrogen on breast cancer development: Role of estrogen receptor independent mechanisms.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Fulvestrant; Humans; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Knockout; Mice, Transgenic; Nitriles; Ovariectomy; Triazoles; Wnt1 Protein | 2010 |
Biological evidence for dual antiangiogenic-antiaromatase activity of the VEGFR inhibitor PTK787/ZK222584 in vivo.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Aromatase; Aromatase Inhibitors; Cell Line, Tumor; Cell Proliferation; Female; Humans; Immunohistochemistry; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neovascularization, Pathologic; Nitriles; Phthalazines; Pyridines; Receptors, Estrogen; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Triazoles; Xenograft Model Antitumor Assays | 2010 |
Inhibitory effects of calcitriol on the growth of MCF-7 breast cancer xenografts in nude mice: selective modulation of aromatase expression in vivo.
Topics: Anastrozole; Animals; Aromatase; Aromatase Inhibitors; Calcitriol; Cell Line, Tumor; Cell Proliferation; Estrogens; Female; Humans; Immunohistochemistry; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Nitriles; Real-Time Polymerase Chain Reaction; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Triazoles; Vitamins; Xenograft Model Antitumor Assays | 2011 |
Dual IGF-1R/InsR inhibitor BMS-754807 synergizes with hormonal agents in treatment of estrogen-dependent breast cancer.
Topics: Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Estradiol; Estrogens; Female; Fulvestrant; Gene Expression Profiling; Humans; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Oligonucleotide Array Sequence Analysis; Pyrazoles; Receptor, IGF Type 1; Receptor, Insulin; Tamoxifen; Triazines; Triazoles; Xenograft Model Antitumor Assays | 2011 |
The effect of second-line antiestrogen therapy on breast tumor growth after first-line treatment with the aromatase inhibitor letrozole: long-term studies using the intratumoral aromatase postmenopausal breast cancer model.
Topics: Animals; Aromatase; Aromatase Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; In Vitro Techniques; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Hormone-Dependent; Nitriles; Receptors, Estrogen; Tamoxifen; Triazoles; Tumor Cells, Cultured | 2002 |
The intratumoral aromatase model: studies with aromatase inhibitors and antiestrogens.
Topics: Androstadienes; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Cell Line, Tumor; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasms, Hormone-Dependent; Nitriles; Tamoxifen; Treatment Outcome; Triazoles | 2003 |
Use of letrozole as a chemopreventive agent in aromatase overexpressing transgenic mice.
Topics: Animals; Anticarcinogenic Agents; Aromatase; Aromatase Inhibitors; Birth Weight; Female; Hyperplasia; Lactation; Letrozole; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Nitriles; Pregnancy; Receptors, Estrogen; RNA, Messenger; Tamoxifen; Triazoles | 2003 |
Preventive effects of letrozole in the model of premenopausal mammary carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Drug Screening Assays, Antitumor; Female; Letrozole; Mammary Neoplasms, Experimental; Menopause; Methylnitrosourea; Nitriles; Rats; Rats, Sprague-Dawley; Triazoles | 2008 |
Effects of gefitinib (Iressa) on mammary cancers: preventive studies with varied dosages, combinations with vorozole or targretin, and biomarker changes.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bexarotene; Biomarkers, Tumor; Carcinogens; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Therapy, Combination; ErbB Receptors; Female; Gefitinib; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Phosphorylation; Quinazolines; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Triazoles | 2008 |
Effect of aromatase inhibitors on growth of mammary tumors in a nude mouse model.
Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Cell Division; Fadrozole; Female; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Organ Size; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Triazoles; Uterus | 1995 |
Growth arrest vs direct cytotoxicity and the importance of molecular structure for the in vitro anti-tumour activity of ether lipids.
Topics: Animals; Antineoplastic Agents; Azepines; Cell Cycle; Cell Division; Cell Membrane; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Mammary Neoplasms, Experimental; Mice; Phospholipid Ethers; Platelet Activating Factor; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured | 1995 |
CAI: effects on cytotoxic therapies in vitro and in vivo.
Topics: Aminoimidazole Carboxamide; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Lewis Lung; Carmustine; Cisplatin; Cyclophosphamide; Fibrosarcoma; Mammary Neoplasms, Experimental; Melphalan; Mice; Triazoles; Tumor Cells, Cultured | 1994 |
Chemopreventive effects of the aromatase inhibitors vorozole (R-83842) and 4-hydroxyandrostenedione in the methylnitrosourea (MNU)-induced mammary tumor model in Sprague-Dawley rats.
Topics: Adenocarcinoma; Aminoglutethimide; Androstenedione; Animals; Anticarcinogenic Agents; Aromatase Inhibitors; Drug Screening Assays, Antitumor; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Triazoles | 1994 |
Anti-tumor and endocrine effects of non-steroidal aromatase inhibitors on estrogen-dependent rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aromatase Inhibitors; Estradiol; Female; Letrozole; Luteinizing Hormone; Mammary Neoplasms, Experimental; Molecular Structure; Nitriles; Organ Size; Rats; Rats, Sprague-Dawley; Tetrazoles; Triazoles; Uterus | 1993 |
Effects of combined and sequential treatment with tamoxifen and the aromatase inhibitor vorozole on 7,12-dimethylbenz(a) anthracene-induced mammary carcinoma in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Carcinogens; Disease Models, Animal; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Ovariectomy; Progesterone; Rats; Rats, Sprague-Dawley; Tamoxifen; Triazoles | 1996 |
A novel in vitro and in vivo breast cancer model for testing inhibitors of estrogen biosynthesis and its action using mammary tumor cells with an activated int-5/aromatase gene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Analysis of Variance; Anastrozole; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Enzyme Inhibitors; Fadrozole; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Ovariectomy; Postmenopause; Triazoles; Tumor Cells, Cultured | 1997 |
Photodynamic therapy using a protoporphyrinogen oxidase inhibitor.
Topics: Animals; Antineoplastic Agents; Dihematoporphyrin Ether; Enzyme Inhibitors; Female; Flavoproteins; Light; Mammary Neoplasms, Experimental; Mice; Mice, Inbred DBA; Microcirculation; Mitochondrial Proteins; Muscle, Skeletal; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Photochemotherapy; Protoporphyrinogen Oxidase; Sulfonamides; Time Factors; Triazoles | 1997 |
Preclinical studies using the intratumoral aromatase model for postmenopausal breast cancer.
Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Drug Screening Assays, Antitumor; Endometrial Neoplasms; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasms, Hormone-Dependent; Nitriles; Organ Size; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles; Tumor Cells, Cultured; Uterus | 1998 |
Chemopreventive effects of the aromatase inhibitor vorozole (R 83842) in the methylnitrosourea-induced mammary cancer model.
Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Body Weight; Carcinogens; Drug Administration Schedule; Drug Screening Assays, Antitumor; Estradiol; Estrus; Female; Genes, ras; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Testosterone; Triazoles | 1998 |
The effects of aromatase inhibitors and antiestrogens in the nude mouse model.
Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Nitriles; Tamoxifen; Triazoles; Tumor Cells, Cultured | 1998 |
A novel aromatase inhibitor, vorozole, shows antitumor activity and a decrease of tissue insulin-like growth factor-I level in 7, 12-dimethylbenz[a]anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents; Aromatase Inhibitors; Enzyme Inhibitors; Female; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Rats; Triazoles | 1999 |
The effect of combining aromatase inhibitors with antiestrogens on tumor growth in a nude mouse model for breast cancer.
Topics: Analysis of Variance; Anastrozole; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase; Aromatase Inhibitors; Disease Models, Animal; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Tamoxifen; Time Factors; Triazoles; Tumor Cells, Cultured | 1999 |
Aromatase overexpression and breast hyperplasia, an in vivo model--continued overexpression of aromatase is sufficient to maintain hyperplasia without circulating estrogens, and aromatase inhibitors abrogate these preneoplastic changes in mammary glands.
Topics: Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogens; Female; Hyperplasia; Letrozole; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Neoplasms, Hormone-Dependent; Nitriles; Ovariectomy; Precancerous Conditions; Receptors, Estrogen; Triazoles | 1999 |
Cellular responses of mammary carcinomas to aromatase inhibitors: effects of vorozole.
Topics: Animals; Antineoplastic Agents; Apoptosis; Aromatase Inhibitors; Biomarkers, Tumor; Cell Division; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Triazoles | 2000 |
Technetium-99m-cyclam AK 2123: a novel marker for tumor hypoxia.
Topics: Animals; Cell Hypoxia; Female; Lung Neoplasms; Mammary Neoplasms, Experimental; Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Tissue Distribution; Triazoles | 2001 |
Altered gene expression profile in chemically induced rat mammary adenocarcinomas and its modulation by an aromatase inhibitor.
Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Aromatase; Aromatase Inhibitors; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Sequence Homology, Amino Acid; Triazoles; Up-Regulation | 2001 |
Effect of the aromatase inhibitor vorozole on estrogen and progesterone receptor content of rat mammary carcinomas induced by 1-methyl-1-nitrosourea.
Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Cell Division; Diet; Drug Administration Schedule; Epithelial Cells; Female; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Triazoles | 2001 |
Aromatase overexpression transgenic mice model: cell type specific expression and use of letrozole to abrogate mammary hyperplasia without affecting normal physiology.
Topics: Animals; Aromatase; Aromatase Inhibitors; Enzyme Inhibitors; Epithelial Cells; Estradiol; Estrogens; Female; Follicle Stimulating Hormone; Gene Expression; Hyperplasia; Letrozole; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Nitriles; RNA, Messenger; Stromal Cells; Tissue Distribution; Triazoles | 2001 |
Aromatase and COX-2 expression in human breast cancers.
Topics: Adipocytes; Adult; Aged; Aged, 80 and over; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cyclooxygenase 2; Dinoprostone; Endothelium; Enzyme Inhibitors; Epithelial Cells; Estrogen Receptor Modulators; Estrogens; Female; Humans; Immunohistochemistry; Isoenzymes; Letrozole; Mammary Neoplasms, Experimental; Membrane Proteins; Mice; Mice, Inbred BALB C; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Prostaglandin-Endoperoxide Synthases; Stromal Cells; Tamoxifen; Triazoles | 2001 |
Carcinogenic and antitumor effects of aminotriazole on acatalasemic and normal catalase mice.
Topics: Amitrole; Animals; Antineoplastic Agents; Carcinogens; Catalase; Female; Liver Neoplasms; Lymphoma; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Triazoles | 1978 |
Antitumoral and endocrine effects of (+)-vorozole in rats bearing dimethylbenzanthracene-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aromatase Inhibitors; Drug Administration Schedule; Drug Screening Assays, Antitumor; Estradiol; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Mammary Neoplasms, Experimental; Ovariectomy; Random Allocation; Rats; Rats, Inbred Strains; Triazoles | 1992 |
Endocrine and antitumoral effects of R76713 in rats.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Antineoplastic Agents; Aromatase Inhibitors; Body Weight; Estradiol; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Organ Size; Ovariectomy; Ovary; Progesterone; Rats; Rats, Inbred Strains; Triazoles; Uterus | 1990 |
X-accumulation of labelled aminotriazole in some transplanted tumours in mice.
Topics: Animals; Autoradiography; Carbon Radioisotopes; Carcinoma; Fibrosarcoma; Intestines; Kidney; Liver; Lymphoma; Mammary Neoplasms, Experimental; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Spleen; Time Factors; Transplantation, Homologous; Triazoles | 1974 |