Compounds > triazoles
Page last updated: 2024-08-24

triazoles and Edema

triazoles has been researched along with Edema in 114 studies

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-199011 (9.65)18.7374
1990's28 (24.56)18.2507
2000's28 (24.56)29.6817
2010's38 (33.33)24.3611
2020's9 (7.89)2.80

Authors

AuthorsStudies
Baroni, ACM; Carvalho, DB; Carvalho, MG; Cassamale, TB; das Neves, AR; Duarte, RCF; Felipe, JL; Lourenço, LD; Toffoli-Kadri, MC1
da Silva, AR; de Carvalho da Silva, F; Faria, RX; Ferreira, VF; Fuly, AL; Gonzaga, DTG; Magalhães, BQ; Pacheco, PAF; Pereira, JS; Pinheiro, NG; Rodrigues, CR; Silva, AC; von Ranke, NL1
Grishina, M; Naumovich, V; Pathak, P; Potemkin, V; Shukla, PK; Verma, A1
Cardoso, CS; Costa, EA; Dos Santos, FCA; Fajemiroye, JO; Florentino, IF; Lião, LM; Lima, DDS; Menegatti, R; Moreira, LKS; Sanz, G; Silva, DM; Silva, DPB; Vasconcelos, JP; Vaz, BG1
Ahmed, I; Assim Haq, S; Chibber, P; Kumar, A; Kumar, C; Singh, A; Singh, G; Singh, S; Vishwakarma, R1
Avci, A; Can, ÖD; Gökhan-Kelekçi, N; Kandemir, Ü; Taşci, H; Tozkoparan, B1
Bansode, MU; Doshi, GM; Somani, RR1
Eleftheriou, P; Gavalas, A; Geronikaki, A; Haroun, M; Kamoutsis, C; Kochkar, H; Nair, AB; Paparisva, A; Petrou, A; Tratrat, C; Venugopala, KN1
Abdelall, EKA; Abdellatif, KRA; Elshemy, HAH; Hassanein, EHM; Kahk, NM; Philoppes, JN1
Ertan, M; Kazkayasi, I; Sert-Ozgur, S; Somuncuoglu, EI; Tel, BC; Tozkoparan, B1
Dalal, R; Grewal, AS; Lather, V; Pandita, D1
Matharasala, G; Perumal, Y; Samala, G1
Abdel-Aziz, M; Abdelhamid, D; Dalby, KN; Hassan, HA; Kaoud, TS; Mohassab, AM1
Alam, O; Amir, M; Kamboj, P; Tariq, S1
Assis, SPO; Fonseca, CSMD; Lima, VLM; Oliveira, RN; Sant'Anna, MP; Santos, CFBD; Seabra, G; Silva, FTD; Silva, MTD; Tenório, CMBA1
Ashour, HM; Fahmy, SM; Ibrahim, TM; Khalil, MA; Labouta, IM; Nassra, RA; Tageldin, GN1
elTahir, KE; Radwan, AA1
Ahmadi, F; Alipoiur, E; Amini, M; Ghayahbashi, MR; khademi, HR; Ostad, SN; Sharifzadeh, M; Vosooghi, M1
Abdel-Aziz, M; Abuo-Rahma, Gel-D; Ali, TF; Beshr, EA2
Abdel-Alim, AA; Abdel-Moty, SG; Hussein, MA; Mohammed, AF1
Alam, A; Alam, MS; Ali, Y; Haider, S; Hamid, H; Kalle, AM; Kharbanda, C; Mahajan, P; Nargotra, A; Nazreen, S; Panda, AK; Shafi, S1
Abdel-Aziz, M; Abdel-Rahman, IM; Aly, OM; Beshr, EA; Ozadali, K; Tan, OU1
Alam, MS; Alam, P; Ali, Y; Bano, S; Dhulap, A; Haider, S; Hamid, H; Hussain, F; Kharbanda, C; Nazreen, S; Pasha, MA; Shafi, S; Umar, S1
Alfei, S; Ballabeni, V; Barocelli, E; Bertoni, S; Di Braccio, M; Flammini, L; Giorgio, C; Grossi, G; Tognolini, M1
Jung, H; Jung, KY; Kim, TW; Lee, YH; Lim, Y; Park, KH; Shin, SY; Yong, Y1
Ertan, M; Kazkayasi, I; Okay, G; Ozadali-Sari, K; Sarigol, D; Somuncuoglu, EI; Tel, BC; Tozkoparan, B; Unsal-Tan, O; Uzgoren-Baran, A1
Ahmed, EA; Mekheimer, RA; Sadek, KU; Sayed, AA1
Baculi, F; Bates, RJ; Bennett, B; Blease, K; Brown, H; Burnett, K; Celeridad, M; Chamberlain, P; Delgado, M; Ferguson, GD; Haelewyn, J; Hickman, M; Jackson, P; Jensen-Pergakes, K; LeBrun, L; Miyazawa, K; Nadolny, L; Nguyen, T; Packard, G; Pagarigan, B; Pierce, S; Plantevin-Krenitsky, V; Tang, Y; Tehrani, L; Torres, S; Xie, W; Xu, L1
Alam, MS; Ali, Y; Hamid, H; Hussain, F; Khan, I; Sharma, K; Tantray, MA; Umar, S1
Gong, GH; Jin, XJ; Liu, DC; Quan, ZS; Wei, CX1
Goto, S; Itoh, H; Nagai, M; Ohmori, K; Osada, H; Sasaki, K; Shimizu, S; Shimoda, M; Shirai, J; Watanabe, M1
Bhardwaj, A; Kaur, J; Wuest, F; Wuest, M1
Bloechle, C; Izbicki, JR; Kaifi, J; Kluth, D; Mann, O; Schneider, C; Strate, T; Tiefenbacher, WJ; Yekebas, E1
Aktay, G; Ertan, M; Tozkoparan, B1
Mikhail, N1
Aktay, G; Aytaç, SP; Tozkoparan, B1
Kalluraya, B; Rao, JN; Shetty, P; Sujith, KV1
Aktay, G; Aytaç, SP; Göktaş, O; Kaynak, FB; Tozkoparan, B; Unüvar, S1
Rajagopal, KA; Rajasekaran, A1
Abdalla, M; Ghorab, MM; Ismail, ZH1
Appenzeller, M; Bigliardi, P; Buclin, T; Grouzmann, E; Pannatier, A1
Aoki, S; Hamachi, E; Imanishi, J; Kuno, M; Kuroda, K; Masunaga, T; Miyata, S; Morita, Y; Mutoh, S; Nakamura, K; Ohkubo, Y; Takahashi, F; Yamagami, K; Yoshimi, E1
Ameen, MA; Hussein, MA; Mohammed, MF; Shaker, RM1
Fujii, Y; Fukasawa, Y; Goitsuka, R; Hara, T; Hirayama, T; Igarashi, Y; Ohtake, H; Ono, N; Sakurai, T; Shiozawa, F; Takahashi, S; Takayama, T; Tsukahara, N1
Alam, MM; Alam, MS; Kalle, AM; Mulakayala, C; Mulakayala, N; Pallu, R; Shafi, S; Vanaja, G1
Alam, MM; Alam, MS; Haider, S; Hamid, H; Nazreen, S; Shaharyar, M1
El-Ashmawy, IM; Rizk, OH; Shaaban, OG1
Ertan, M; Kazkayası, I; Okay, G; Oztürk, Eİ; Sarıgöl, D; Tel, BC; Tozkoparan, B; Uzgören-Baran, A1
Garigipati, S; Kundu, B; Semwal, A; Sharma, M; Sriram, D; Vanamala, D; Yogeeswari, P1
Aydinok, Y; Chan, LL; El-Beshlawy, A; Elalfy, MS; Habr, D; Lee, SH; Martin, N; Porter, JB; Sutcharitchan, P; Taher, AT1
Mahé, E; Sigal, ML; Sin, C1
Assis, SP; da Silva, MT; de Oliveira, RN; Lima, VL1
Ashour, HM; El-Ashmawy, IM; Rizk, OH; Shaaban, OG1
Assreuy, AM; Feitosa, RF; Lima, AA; Melcíades, GB; Ribeiro, RA; Rocha, MF1
Alcaraz, MJ; Aller, E; Fernández, P; Guillén, MI; López-Cremades, P; Lorenzo, A; Molina, P; Ubeda, A1
Day, YJ; Huang, L; Linden, J; Marshall, MA; McDuffie, MJ; Okusa, MD1
Ertan, M; Gökhan, N; Küpeli, E; Tozkoparan, B; Yeşilada, E1
Brukstus, A; Gaidelis, P; Labanauskas, L; Udrenaite, E1
Ertan, M; Işik, S; Küpeli, E; Ozalp, M; Tozkoparan, B; Yeşilada, E1
Aboul-Fadl, T; El-Koussi, NA; Hassan, HY; Rabea, SM1
Al-Deeb, OA; Al-Omar, MA; El-Brollosy, NR; El-Emam, AA; Habib, EE; Ibrahim, TM1
Aktay, G; Gökhan-Kelekçi, N; Göktaş, O; Işik, S; Kiliç, E; Köysal, Y; Ozalp, M; Salgin-Gökşen, U1
Di Braccio, M; Gosmar, M; Grossi, G; Mattioli, F; Piras, D; Roma, G1
Amir, M; Javed, SA; Kumar, H1
Chevallet, P; Gümüsel, B; Kandilci, HB; Kaplancikli, ZA; Ozdemir, A; Turan-Zitouni, G1
Chen, W; Guo, L; Li, J; Yang, H; Ye, C; Ye, H; Yu, X; Zhang, D; Zheng, R1
Amir, M; Javed, SA; Khan, SA; Kumar, H1
Abdel-Megeed, AM; Abdel-Rahman, HM; Alkaramany, GE; El-Gendy, MA1
Blasi, ER; Ecelbarger, CM; Heyen, JR; McHarg, AD; Tiwari, S1
Maxwell, JR; Stenberg, VI; Wasdahl, DA; Wolfson, AC1
Carlson, R; Dally-Meade, V; Donigi-Ruzza, D; Khandwala, A1
Barthwal, JP; Bhalla, TN; Pande, K; Parmar, SS; Tandon, P; Tangri, KK1
Kissick, TP; Millonig, RC; Palmer, DM; Simpkins, LM; Vogt, BR; Wade, PC1
Barthwal, JP; Bhalla, TN; Bhargava, KP; Tandon, J1
Calvino, R; Mortarini, V; Serafino, A1
Komatsu, H; Nagasawa, M; Okumoto, T1
Das, A; Larkin, SW; Nourshargh, S; Williams, TJ1
Damas, J; Remacle-Volon, G; Sampaio, CA; Souza Pinto, JC1
Furuhama, K; Kawarabayashi, K; Komada, T; Tabuchi, Y1
Ikarashi, Y; Nakamura, A; Tsuchiya, T2
Patterson, JS; Provost, PJ; Stick, JA; Wilson, DV1
Bornemeier, DA; Boschelli, DH; Connor, DT; Dyer, RD; Kennedy, JA; Kuipers, PJ; Okonkwo, GC; Schrier, DJ; Wright, CD1
Cunningham, FM; Foster, AP; Lees, P1
Hellewell, PG; Macari, DM; Teixeira, MM1
Duflos, M; Grimaud, N; Juge, M; Le Baut, G; Petit, JY; Rideau, O; Robert, JM; Robert-Piessard, S1
Desouza, IA; Ribeiro-DaSilva, G1
Gaidelis, P; Mekuskiene, G; Vainilavicius, P1
Abdala, S; Darias, V; Martín Herrera, D; Tello, ML; Vega, S1
Demirdamar, R; Ertan, M; Ertan, R; Kelicen, P; Kilcigil, GA; Tozkoparan, B1
Bon, C; da Cruz-Höfling, MA; de Araújo, AL; de Souza, AO; Flores, CA1
Aktay, G; Ertan, M; Tozkoparan, B; Yesilada, E1
Altinok, G; Demirdamar, R; Kelicen, P; Palaska, E; Sahin, G1
Chiasserini, L; Falcone, G; Filippelli, W; Pellerano, C; Savini, L1
Adam, A; Damas, J; Leroux, JC; Molinaro, G1
Arrigo-Reina, R; Barbera, F; Castorina, C; Catti, T; Chiechio, S; Mazzone, G; Mazzone, S; Panico, A; Pignatello, R; Russo, A1
Donigi-Gale, D; Edwards, R; Norman, KE; Rossi, AG; Shoupe, TS; Williams, TJ1
Bozza, PT; COrdeiro, RS; Faria Neto, HC; Martins, MA; Pasquale, CP; Silva, PM1
Amorim, CZ; Cordeiro, RS; Martins, MA; Vargaftig, BB1
Amorim, CZ; Cordeiro, RS; Henriques, MG; Vargaftig, BB; Weg, VB1
Brain, SD; Buckley, TL; Collins, PD; Williams, TJ1
Boido, A; Cenicola, ML; Donnoli, D; Marmo, E; Sparatore, F; Vazzana, I1
el-Emam, AA; Ibrahim, TM1
Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Correia-Da-Silva, AC; Martins, MA; Morhy, L; Sousa, MV1
Balmes, J; Fine, J; Gordon, T; Sheppard, D1
Barnes, PJ; Dijk, S; Rogers, DF1
Antunes, E; Cirino, G; de Nucci, G; Levi, S; Mariano, M1
Cordeiro, RS; Fernandes, PD; Henriques, MG; Martins, MA; Silva, PM; Vargaftig, BB; Weg, VB1
Ezeamuzie, CI; Umezurike, CC1
Graczyk, J; Kiełek, MB; Kowalczyk, K; Pakulska, W; Szadowska, A1
Kreutzberger, A; van der Goot, H1
Carter, GW; Dodge, PW; Kimura, ET; Young, PR1
Dietz, E; Kreutzberger, A1

Reviews

1 review(s) available for triazoles and Edema

ArticleYear
Combination therapy with DPP-4 inhibitors and pioglitazone in type 2 diabetes: theoretical consideration and therapeutic potential.
    Vascular health and risk management, 2008, Volume: 4, Issue:6

    Topics: Adamantane; Blood Glucose; Body Weight; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Edema; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Lipids; Nitriles; Pioglitazone; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Thiazolidinediones; Treatment Outcome; Triazoles; Vildagliptin

2008

Trials

1 trial(s) available for triazoles and Edema

ArticleYear
Substance P-induced skin inflammation is not modulated by a single dose of sitagliptin in human volunteers.
    Biological chemistry, 2011, Volume: 392, Issue:3

    Topics: Capsaicin; Carbonated Beverages; Cross-Over Studies; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Eruptions; Edema; Erythema; Humans; Injections, Intradermal; Male; Pain; Pyrazines; Sitagliptin Phosphate; Skin; Substance P; Triazoles; Vasodilation

2011

Other Studies

112 other study(ies) available for triazoles and Edema

ArticleYear
Anti-inflammatory, ulcerogenic and platelet activation evaluation of novel 1,4-diaryl-1,2,3-triazole neolignan-celecoxib hybrids.
    Bioorganic chemistry, 2022, Volume: 119

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Carrageenan; Celecoxib; Dose-Response Relationship, Drug; Edema; Lignans; Male; Mice; Molecular Structure; Peritonitis; Platelet Activation; Platelet Aggregation Inhibitors; Rats; Structure-Activity Relationship; Triazoles; Ulcer

2022
Triazoles with inhibitory action on P2X7R impaired the acute inflammatory response in vivo and modulated the hemostatic balance in vitro and ex vivo.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2023, Volume: 72, Issue:2

    Topics: Animals; Carrageenan; Edema; Hemostatics; Inflammation; Mice; Molecular Docking Simulation; Peritonitis; Triazoles

2023
1,2,4-Triazole-conjugated 1,3,4-thiadiazole hybrid scaffolds: A potent ameliorant of carrageenan-induced inflammation by lessening proinflammatory mediators.
    Archiv der Pharmazie, 2020, Volume: 353, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Edema; Inflammation; Inflammation Mediators; Molecular Docking Simulation; Molecular Structure; Quantitative Structure-Activity Relationship; Rats; Rats, Wistar; Thiadiazoles; Triazoles

2020
Mechanisms involved in the antinociceptive and anti-inflammatory effects of a new triazole derivative: 5-[1-(4-fluorophenyl)-1H-1,2,3-triazol-4-yl]-1H-tetrazole (LQFM-096).
    Inflammopharmacology, 2020, Volume: 28, Issue:4

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cell Movement; Dinoprostone; Edema; Female; Hyperalgesia; Leukocytes; Mice; Nociception; Pain Measurement; Pleurisy; Tetrazoles; Triazoles

2020
Anti-inflammatory and analgesic potential of OA-DHZ; a novel semisynthetic derivative of dehydrozingerone.
    International immunopharmacology, 2020, Volume: 83

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Carrageenan; Cytokines; Edema; Female; Humans; Inflammation Mediators; Plant Extracts; Rats; Rats, Wistar; Styrenes; Triazoles; Zingiber officinale

2020
Synthesis, characterization, and in vivo pharmacological evaluation of novel mannich bases derived from 1,2,4-triazole containing a naproxen moiety.
    Bioorganic chemistry, 2020, Volume: 100

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Drug Design; Edema; Humans; Male; Mannich Bases; Mice, Inbred BALB C; Molecular Docking Simulation; Naproxen; Pain; Triazoles

2020
Evaluation of Biological Activity of Derivatives of 1,3,4-Thiadiazole, 1,3,4-Oxadiazole and 1,2,4-Triazole.
    Endocrine, metabolic & immune disorders drug targets, 2021, Volume: 21, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Edema; Erythrocyte Membrane; Female; Male; Oxadiazoles; Peptide Hydrolases; Protease Inhibitors; Rats; Thiadiazoles; Triazoles

2021
New Substituted 5-Benzylideno-2-Adamantylthiazol[3,2-b][1,2,4]Triazol-6(5
    Molecules (Basel, Switzerland), 2021, Jan-27, Volume: 26, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Female; Humans; Inflammation; Lipoxygenase; Lipoxygenase Inhibitors; Male; Mice; Molecular Docking Simulation; Naproxen; Structure-Activity Relationship; Triazoles

2021
Optimization of pyrazole-based compounds with 1,2,4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory, ulcerogenicity, cardiovascular evaluation, and mol
    Bioorganic chemistry, 2021, Volume: 114

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiotonic Agents; Carrageenan; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Design; Edema; Inflammation; Male; Models, Molecular; Molecular Structure; Pyrazoles; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship; Triazoles

2021
Design and Synthesis of 1,2,4-Triazolo[3,2-b]-1,3,5-thiadiazine Derivatives as a Novel Template for Analgesic/Anti-Inflammatory Activity.
    Archiv der Pharmazie, 2017, Volume: 350, Issue:7

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Carrageenan; Disease Models, Animal; Drug Design; Edema; Hot Temperature; Mice; Molecular Structure; Pain; Stomach Ulcer; Thiadiazines; Triazoles

2017
Synthesis, Docking and Anti-Inflammatory Activity of Triazole Amine Derivatives as Potential Phosphodiesterase-4 Inhibitors.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2017, Volume: 16, Issue:1

    Topics: Amines; Animals; Anti-Inflammatory Agents; Carrageenan; Cyclic Nucleotide Phosphodiesterases, Type 4; Edema; Molecular Docking Simulation; Phosphodiesterase 4 Inhibitors; Rats, Wistar; Triazoles

2017
MG17, A Novel Triazole Derivative Abrogated Neuroinflammation and Related Neurodegenerative Symptoms in Rodents.
    Current molecular pharmacology, 2018, Volume: 11, Issue:2

    Topics: Animals; Brain; Carrageenan; Cell Survival; Diabetic Neuropathies; Edema; Inflammation; Inhibitory Concentration 50; Male; Mice; Motor Activity; Nerve Degeneration; Rats, Wistar; rho-Associated Kinases; RNA, Messenger; Triazoles

2018
Novel quinoline incorporating 1,2,4-triazole/oxime hybrids: Synthesis, molecular docking, anti-inflammatory, COX inhibition, ulceroginicity and histopathological investigations.
    Bioorganic chemistry, 2017, Volume: 75

    Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Edema; Enzyme Activation; Gastric Mucosa; Inhibitory Concentration 50; Kinetics; Liver; Molecular Docking Simulation; Nitric Oxide; Oximes; Quinolines; Rats; Structure-Activity Relationship; Triazoles

2017
1,2,4-Triazole-based benzothiazole/benzoxazole derivatives: Design, synthesis, p38α MAP kinase inhibition, anti-inflammatory activity and molecular docking studies.
    Bioorganic chemistry, 2018, Volume: 81

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Benzoxazoles; Edema; Molecular Docking Simulation; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Rats, Wistar; Triazoles

2018
Design and Synthesis of Triazole-Phthalimide Hybrids with Anti-inflammatory Activity.
    Chemical & pharmaceutical bulletin, 2019, Volume: 67, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Edema; Phthalimides; Structure-Activity Relationship; Triazoles

2019
Synthesis, modeling and biological evaluation of some pyrazolo[3,4-d]pyrimidinones and pyrazolo[4,3-e][1,2,4]triazolo[4,3-a]pyrimidinones as anti-inflammatory agents.
    Bioorganic chemistry, 2019, Volume: 90

    Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Edema; Female; Granuloma; Inflammation; Molecular Docking Simulation; Molecular Structure; Pyrazoles; Pyrimidinones; Rats, Wistar; Structure-Activity Relationship; Triazoles

2019
Synthesis and in-silico studies of some diaryltriazole derivatives as potential cyclooxygenase inhibitors.
    Archives of pharmacal research, 2013, Volume: 36, Issue:5

    Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Edema; Male; Models, Molecular; Molecular Docking Simulation; Rats; Rats, Sprague-Dawley; Triazoles

2013
Synthesis and evaluation of anti-inflammatory and analgesic activities of new 1,2,4-triazole derivatives.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2014, Volume: 11, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Hindlimb; Indomethacin; Injections, Intraperitoneal; Male; Mice; Morphine; Pain; Rats; Rats, Wistar; Triazoles

2014
New nitric oxide donating 1,2,4-triazole/oxime hybrids: synthesis, investigation of anti-inflammatory, ulceroginic liability and antiproliferative activities.
    Bioorganic & medicinal chemistry, 2013, Jul-01, Volume: 21, Issue:13

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Line, Tumor; Edema; Humans; Kidney Neoplasms; Male; Nitric Oxide; Nitric Oxide Donors; Oximes; Rats; Stomach; Triazoles; Ulcer

2013
Design, synthesis and molecular docking of some new 1,2,4-triazolobenzimidazol-3-yl acetohydrazide derivatives with anti-inflammatory-analgesic activities.
    Archives of pharmacal research, 2013, Volume: 36, Issue:12

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzimidazoles; Drug Design; Edema; Male; Mice; Molecular Docking Simulation; Pain; Protein Binding; Rats; Structure-Activity Relationship; Triazoles

2013
Synthesis of novel 1,2,3-triazole based benzoxazolinones: their TNF-α based molecular docking with in-vivo anti-inflammatory, antinociceptive activities and ulcerogenic risk evaluation.
    European journal of medicinal chemistry, 2013, Volume: 70

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoxazoles; Carrageenan; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Edema; Epithelial Cells; Gastric Mucosa; Humans; Models, Molecular; Molecular Structure; Rats; Risk Factors; Structure-Activity Relationship; Triazoles; Tumor Necrosis Factor-alpha

2013
1,2,4-Triazole/oxime hybrids as new strategy for nitric oxide donors: Synthesis, anti-inflammatory, ulceroginicity and antiproliferative activities.
    European journal of medicinal chemistry, 2014, Volume: 71

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Edema; Humans; Male; Neoplasms; Nitric Oxide Donors; Oximes; Rats; Stomach Ulcer; Triazoles

2014
1-(4-Methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole-3-carboxamides: synthesis, molecular modeling, evaluation of their anti-inflammatory activity and ulcerogenicity.
    European journal of medicinal chemistry, 2014, Apr-22, Volume: 77

    Topics: Animals; Anisoles; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Edema; Hydrazines; Male; Models, Molecular; Molecular Structure; Rats; Stomach Ulcer; Structure-Activity Relationship; Triazoles

2014
Synthesis of novel 2-mercaptobenzoxazole based 1,2,3-triazoles as inhibitors of proinflammatory cytokines and suppressors of COX-2 gene expression.
    European journal of medicinal chemistry, 2014, Jun-23, Volume: 81

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoxazoles; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytokines; Edema; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Inflammation; Mice; Models, Molecular; Pain; Rats; Rats, Wistar; Sulfhydryl Compounds; Triazoles; Tumor Cells, Cultured

2014
1,8-Naphthyridines IX. Potent anti-inflammatory and/or analgesic activity of a new group of substituted 5-amino[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides, of some their Mannich base derivatives and of one novel substituted 5-amino-10-oxo-10H-
    European journal of medicinal chemistry, 2014, Oct-30, Volume: 86

    Topics: Amides; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cells, Cultured; Dose-Response Relationship, Drug; Edema; Guinea Pigs; Locomotion; Mice; Naphthyridines; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Triazoles

2014
Synthesis and biological evaluation of phenyl-1H-1,2,3-triazole derivatives as anti-inflammatory agents.
    Bioorganic chemistry, 2015, Volume: 59

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Ear; Edema; Male; Mice; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Triazoles; Tumor Necrosis Factor-alpha; Xylenes

2015
Novel thiazolo[3,2-b]-1,2,4-triazoles derived from naproxen with analgesic/anti-inflammatory properties: Synthesis, biological evaluation and molecular modeling studies.
    Bioorganic & medicinal chemistry, 2015, May-15, Volume: 23, Issue:10

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; Drug Design; Edema; Humans; Inflammation; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Naproxen; Nociception; Pain; Pain Measurement; Structure-Activity Relationship; Thiazoles; Thiones; Triazoles

2015
Synthesis and Characterization of New 1,2,4-Triazolo[1,5-a]pyridines That Extend the Life Span of Caenorhabiditis elegans via Their Anti-Inflammatory/Antioxidant Effects.
    Archiv der Pharmazie, 2015, Volume: 348, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Caenorhabditis elegans; Carrageenan; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Edema; Glycation End Products, Advanced; Glycosylation; Heat-Shock Response; Longevity; Male; Molecular Structure; Oxidative Stress; Picrates; Pyridines; Rats; Structure-Activity Relationship; Time Factors; Triazoles

2015
A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Animals; Arthritis, Experimental; Basophils; Cell Line; Collagen; Crystallography, X-Ray; Dose-Response Relationship, Drug; Edema; Eosinophils; Female; HEK293 Cells; Humans; Hypertension; Indazoles; Inflammation; Inhibitory Concentration 50; Intracellular Signaling Peptides and Proteins; Janus Kinase 2; Male; Neutropenia; Neutrophils; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Receptors, Fc; Skin; Syk Kinase; Triazoles; Vascular Endothelial Growth Factor Receptor-2

2016
Synthesis of Novel Oxazolo[4,5-b]pyridine-2-one based 1,2,3-triazoles as Glycogen Synthase Kinase-3β Inhibitors with Anti-inflammatory Potential.
    Chemical biology & drug design, 2016, Volume: 87, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Edema; Enzyme Inhibitors; Female; Glycogen Synthase Kinase 3 beta; Male; Nitric Oxide; Rats; Rats, Wistar; Triazoles

2016
Synthesis and anti-inflammatory activity evaluation of a novel series of 6-phenoxy-[1,2,4]triazolo[3,4-a]phthalazine-3-carboxamide derivatives.
    Bioorganic & medicinal chemistry letters, 2016, Mar-15, Volume: 26, Issue:6

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Dose-Response Relationship, Drug; Edema; HeLa Cells; Humans; Injections, Intraperitoneal; Mice; Mice, Inbred Strains; Molecular Structure; NF-kappa B; Phthalazines; Structure-Activity Relationship; Triazoles; Tumor Necrosis Factor-alpha; Xylenes

2016
Characterization of platelet-activating factor-induced cutaneous edema and erythema in dogs.
    American journal of veterinary research, 2016, Volume: 77, Issue:9

    Topics: Animals; Azepines; Dogs; Edema; Erythema; Histamine; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prednisolone; Receptors, G-Protein-Coupled; Skin; Skin Diseases; Triazoles

2016
In situ click chemistry generation of cyclooxygenase-2 inhibitors.
    Nature communications, 2017, 02-23, Volume: 8, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Click Chemistry; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Design; Edema; Female; Gene Expression; Hindlimb; Humans; Kinetics; Molecular Docking Simulation; Protein Structure, Secondary; Pyrazoles; Rats; Structure-Activity Relationship; Thermodynamics; Triazoles

2017
Effect of platelet-activating factor antagonist WEB 2086 on microcirculatory disorders in acute experimental pancreatitis of graded severity.
    Pancreas, 2009, Volume: 38, Issue:1

    Topics: Amylases; Animals; Azepines; Capillaries; Cell Adhesion; Ceruletide; Disease Models, Animal; Edema; Female; Glycodeoxycholic Acid; Leukocytes; Microcirculation; Oligopeptides; Pancreas; Pancreatitis; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Regional Blood Flow; Severity of Illness Index; Taurocholic Acid; Time Factors; Triazoles

2009
Investigation of antioxidant properties of some 6-(alpha-aminobenzyl)thiazolo[3,2-b]-1,2,4-triazole-5-ol compounds.
    Journal of enzyme inhibition and medicinal chemistry, 2009, Volume: 24, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Benzyl Compounds; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Edema; Ethanol; Gastrointestinal Diseases; Inhibitory Concentration 50; Lipid Peroxidation; Male; Mice; Stomach Ulcer; Time Factors; Triazoles

2009
Novel 3,6-disubstituted 7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines: synthesis, characterization, and evaluation of analgesic/anti-inflammatory, antioxidant activities.
    Archiv der Pharmazie, 2009, Volume: 342, Issue:5

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carrageenan; Drug Evaluation, Preclinical; Edema; Female; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred BALB C; Spectrophotometry, Infrared; Stomach Ulcer; Structure-Activity Relationship; Thiadiazines; Triazoles

2009
Regioselective reaction: synthesis and pharmacological study of Mannich bases containing ibuprofen moiety.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:9

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspergillus; Edema; Escherichia coli; Ibuprofen; Inflammation; Mannich Bases; Mice; Pain; Rats; Rats, Wistar; Schiff Bases; Staphylococcus aureus; Triazoles

2009
Synthesis of 3,6-disubstituted 7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines as novel analgesic/anti-inflammatory compounds.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Edema; Female; Male; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Pain Measurement; Thiadiazines; Triazoles; Ulcer

2009
Synthesis of some novel triazole derivatives as anti-nociceptive and anti-inflammatory agents.
    Acta pharmaceutica (Zagreb, Croatia), 2009, Volume: 59, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Discovery; Edema; Injections, Intraperitoneal; Mice; Nuclear Magnetic Resonance, Biomolecular; Pain Measurement; Spectrophotometry, Infrared; Triazoles

2009
Synthesis and biological activities of some novel triazoloquinazolines and triazinoquinazolines containing benzenesulfonamide moieties.
    Arzneimittel-Forschung, 2010, Volume: 60, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Edema; Foot; Formaldehyde; Indicators and Reagents; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Quinazolines; Rats; Rats, Wistar; Spectrophotometry, Infrared; Sulfonamides; Triazines; Triazoles

2010
Pharmacological profile of FK881(ASP6537), a novel potent and selective cyclooxygenase-1 inhibitor.
    Biochemical pharmacology, 2011, Oct-01, Volume: 82, Issue:7

    Topics: Acetic Acid; Animals; Arthritis, Experimental; Carrageenan; CHO Cells; Cricetinae; Cricetulus; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Female; Humans; Hyperalgesia; In Vitro Techniques; Male; Mice; Pain; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Recombinant Proteins; Stomach Ulcer; Triazoles

2011
Synthesis, anti-inflammatory, analgesic, and antibacterial activities of some triazole, triazolothiadiazole, and triazolothiadiazine derivatives.
    Archives of pharmacal research, 2011, Volume: 34, Issue:8

    Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Edema; Escherichia coli; Hot Temperature; Lethal Dose 50; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Rats; Stomach Ulcer; Thiadiazoles; Thiones; Time Factors; Triazoles

2011
Lymphopenia induced by a novel selective S1P(1) antagonist structurally unrelated to S1P.
    Biochimica et biophysica acta, 2012, Volume: 1821, Issue:4

    Topics: Animals; Chemotaxis; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dermatitis, Contact; Ear; Edema; Female; Guanosine 5'-O-(3-Thiotriphosphate); HEK293 Cells; Humans; Hyperplasia; Leukocytes; Lymphopenia; Lysophospholipids; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Protein Binding; Rats; Rats, Inbred Lew; Receptors, Lysosphingolipid; Sphingosine; Sulfonamides; Triazoles

2012
Synthesis of novel 2-mercapto benzothiazole and 1,2,3-triazole based bis-heterocycles: their anti-inflammatory and anti-nociceptive activities.
    European journal of medicinal chemistry, 2012, Volume: 49

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzothiazoles; Click Chemistry; Cyclooxygenase Inhibitors; Edema; Female; Humans; Male; Models, Molecular; Nociception; Rats; Rats, Wistar; Triazoles

2012
Synthesis of novel 8-hydroxy quinolin based 1,3,4-oxadiazoles and S-substituted 1,2,4-triazole derivatives and evaluation of their anti-inflammatory, analgesic, ulcerogenic and anti-microbial activities.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2011, Volume: 7, Issue:6

    Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Edema; Gram-Negative Bacteria; Microbial Sensitivity Tests; Molecular Structure; Oxadiazoles; Quinolones; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship; Triazoles

2011
Design, synthesis and biological evaluation of some novel thienopyrimidines and fused thienopyrimidines as anti-inflammatory agents.
    European journal of medicinal chemistry, 2012, Volume: 55

    Topics: Animals; Anti-Inflammatory Agents; Chemistry Techniques, Synthetic; Drug Design; Edema; Formaldehyde; Granuloma; Male; Pyrimidines; Rats; Triazoles; Turpentine; Ulcer

2012
Thiazolo[3,2-b]-1,2,4-triazole-5(6H)-one substituted with ibuprofen: novel non-steroidal anti-inflammatory agents with favorable gastrointestinal tolerance.
    European journal of medicinal chemistry, 2012, Volume: 57

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dose-Response Relationship, Drug; Drug Tolerance; Edema; Female; Ibuprofen; Indomethacin; Male; Mice; Pain Measurement; Stomach; Stomach Ulcer; Structure-Activity Relationship; Triazoles

2012
Discovery of novel 1,2,4-triazol-5-ones as tumor necrosis factor-alpha inhibitors for the treatment of neuropathic pain.
    Chemical biology & drug design, 2012, Volume: 80, Issue:6

    Topics: Analgesics; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Edema; Humans; Mice; Neuralgia; Rats; Rats, Wistar; Structure-Activity Relationship; Triazoles; Tumor Necrosis Factor-alpha

2012
Efficacy and safety of deferasirox at low and high iron burdens: results from the EPIC magnetic resonance imaging substudy.
    Annals of hematology, 2013, Volume: 92, Issue:2

    Topics: Adolescent; Adult; Benzoates; Chelation Therapy; Child; Child, Preschool; Cholelithiasis; Clinical Trials, Phase III as Topic; Creatinine; Deferasirox; Edema; Ethnicity; Female; Ferritins; Gastrointestinal Diseases; Hematologic Diseases; Hepatitis, Viral, Human; Humans; Infant; Iron; Iron Chelating Agents; Iron Overload; Kidney Diseases; Liver; Magnetic Resonance Imaging; Male; Multicenter Studies as Topic; Prospective Studies; Thalassemia; Transfusion Reaction; Triazoles; Young Adult

2013
Drug reaction with eosinophilia and systemic symptoms (DRESS) in a patient taking sitagliptin.
    Diabetes & metabolism, 2012, Volume: 38, Issue:6

    Topics: Acute Kidney Injury; Aged; Back; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Ear; Edema; Eosinophilia; Exanthema; Female; Glucocorticoids; Humans; Prednisone; Pyrazines; Sitagliptin Phosphate; Triazoles

2012
Synthesis and anti-inflammatory activity of new alkyl-substituted phthalimide 1H-1,2,3-triazole derivatives.
    TheScientificWorldJournal, 2012, Volume: 2012

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Edema; Inflammation; Mice; Phthalimides; Triazoles

2012
Synthesis and biological evaluation of thieno [2',3':4,5]pyrimido[1,2-b][1,2,4]triazines and thieno[2,3-d][1,2,4]triazolo[1,5-a]pyrimidines as anti-inflammatory and analgesic agents.
    European journal of medicinal chemistry, 2013, Volume: 62

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Edema; Formaldehyde; Male; Molecular Structure; Pyrimidines; Rats; Rats, Wistar; Structure-Activity Relationship; Thiophenes; Triazines; Triazoles

2013
The pharmacological profile of ovalbumin-induced paw oedema in rats.
    Mediators of inflammation, 2002, Volume: 11, Issue:3

    Topics: Animals; Anti-Allergic Agents; Azepines; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Immunologic; Edema; Enzyme Inhibitors; Foot; Histamine H1 Antagonists; Hypersensitivity; Immunization; Immunosuppressive Agents; Ketotifen; Ovalbumin; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Triazoles

2002
A novel indazolo-triazolo-benzotriazepine exerts anti-inflammatory effects by inhibition of cyclooxygenase-2 activity and nitric oxide synthase-2 expression.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 368, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Blood Platelets; Blotting, Western; Carrageenan; Cell Survival; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Electrophoretic Mobility Shift Assay; Female; Humans; Indazoles; Isoenzymes; Macrophages; Membrane Proteins; Mice; Microsomes; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Prostaglandin-Endoperoxide Synthases; Triazoles

2003
Protection from ischemic liver injury by activation of A2A adenosine receptors during reperfusion: inhibition of chemokine induction.
    American journal of physiology. Gastrointestinal and liver physiology, 2004, Volume: 286, Issue:2

    Topics: Adenosine A2 Receptor Agonists; Animals; Blood Cells; Chemokines; Cyclohexanecarboxylic Acids; Cytokines; Drug Administration Schedule; Edema; Gene Deletion; Ischemia; Leukocytes; Liver; Liver Circulation; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Purines; Radioligand Assay; Receptor, Adenosine A2A; Reperfusion Injury; RNA, Messenger; Triazines; Triazoles

2004
Synthesis, characterization and antiinflammatory-analgesic properties of 6-(alpha-amino-4-chlorobenzyl)thiazolo [3,2-b]-1,2,4-triazol-5-ols.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:1

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoquinones; Capillary Permeability; Carrageenan; Chemical Phenomena; Chemistry, Physical; Edema; Foot; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mice; Models, Molecular; Molecular Conformation; Naproxen; Pain; Spectroscopy, Fourier Transform Infrared; Stomach Ulcer; Structure-Activity Relationship; Thiazoles; Triazoles

2004
Synthesis of 5-(2-,3- and 4-methoxyphenyl)-4H-1,2,4-triazole-3-thiol derivatives exhibiting anti-inflammatory activity.
    Farmaco (Societa chimica italiana : 1989), 2004, Volume: 59, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Edema; Male; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar; Sulfhydryl Compounds; Triazoles

2004
Synthesis and evaluation of analgesic/ anti-inflammatory and antimicrobial activities of 3-substituted- 1,2,4-triazole-5-thiones.
    Arzneimittel-Forschung, 2005, Volume: 55, Issue:9

    Topics: Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Biological Assay; Carrageenan; Edema; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mice; Microbial Sensitivity Tests; Models, Molecular; Spectrophotometry, Infrared; Stomach Ulcer; Thiones; Triazoles

2005
Synthesis of 5-phenyl-1-(3-pyridyl)-1H-1,2,4-triazole-3-carboxylic acid derivatives of potential anti-inflammatory activity.
    Archiv der Pharmazie, 2006, Volume: 339, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Dose-Response Relationship, Drug; Edema; Lethal Dose 50; Male; Rats; Rats, Wistar; Semicarbazides; Stomach Ulcer; Structure-Activity Relationship; Triazoles

2006
Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-[3-(1-adamantyl)-4-substituted-5-thioxo-1,2,4-triazolin-1-yl] acetic acids, 2-[3-(1-adamantyl)-4-substituted-5-thioxo-1,2,4-triazolin-1-yl]propionic acids and related derivatives.
    Arzneimittel-Forschung, 2006, Volume: 56, Issue:1

    Topics: Algorithms; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Candida albicans; Carrageenan; Edema; Indicators and Reagents; Injections, Intraperitoneal; Magnetic Resonance Spectroscopy; Male; Microbial Sensitivity Tests; Propionates; Rats; Rats, Sprague-Dawley; Triazoles

2006
1-Acylthiosemicarbazides, 1,2,4-triazole-5(4H)-thiones, 1,3,4-thiadiazoles and hydrazones containing 5-methyl-2-benzoxazolinones: synthesis, analgesic-anti-inflammatory and antimicrobial activities.
    Bioorganic & medicinal chemistry, 2007, Sep-01, Volume: 15, Issue:17

    Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Benzoxazoles; Crystallography, X-Ray; Edema; Hindlimb; Hydrazones; Methylation; Mice; Microbial Viability; Models, Molecular; Molecular Structure; Semicarbazides; Structure-Activity Relationship; Thiadiazoles; Triazoles

2007
1,8-Naphthyridines VI. Synthesis and anti-inflammatory activity of 5-(alkylamino)-N,N-diethyl[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides with a new substitution pattern on the triazole ring.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Drug Design; Edema; Inflammation; Male; Naphthyridines; Rats; Rats, Sprague-Dawley; Triazoles

2008
Non-carboxylic analogues of naproxen: design, synthesis, and pharmacological evaluation of some 1,3,4-oxadiazole/thiadiazole and 1,2,4-triazole derivatives.
    Archiv der Pharmazie, 2007, Volume: 340, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Drug Design; Edema; Liver; Liver Function Tests; Male; Mice; Molecular Structure; Naproxen; Oxadiazoles; Pain; Rats; Stomach Ulcer; Thiadiazoles; Triazoles

2007
Studies on 1,2,4-triazole derivatives as potential anti-inflammatory agents.
    Archiv der Pharmazie, 2007, Volume: 340, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Contraindications; Edema; Female; Male; Mice; Molecular Structure; Structure-Activity Relationship; Triazoles

2007
Anti-inflammatory and analgesic potency of carboxyamidotriazole, a tumorostatic agent.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis; Capillary Permeability; Disease Models, Animal; Edema; Female; Granuloma; Interleukin-1; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Rats; Rats, Wistar; Triazoles; Tumor Necrosis Factor-alpha

2008
1,3,4-Oxadiazole/thiadiazole and 1,2,4-triazole derivatives of biphenyl-4-yloxy acetic acid: synthesis and preliminary evaluation of biological properties.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:12

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Carrageenan; Diphenylacetic Acids; Drug Evaluation, Preclinical; Edema; Female; Gastric Mucosa; Lipid Peroxidation; Liver; Male; Mice; Molecular Structure; Oxadiazoles; Rats; Rats, Wistar; Stereoisomerism; Stomach Ulcer; Thiadiazoles; Triazoles

2008
Design, synthesis and molecular modeling study of acylated 1,2,4-triazole-3-acetates with potential anti-inflammatory activity.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:1

    Topics: Acetates; Acylation; Animals; Anti-Inflammatory Agents; Drug Design; Drug-Related Side Effects and Adverse Reactions; Edema; Models, Molecular; Molecular Structure; Rats; Stomach Ulcer; Triazoles

2009
Time course of AQP-2 and ENaC regulation in the kidney in response to PPAR agonists associated with marked edema in rats.
    Pharmacological research, 2008, Volume: 57, Issue:5

    Topics: Adiponectin; Animals; Aquaporin 2; Blood Pressure; Edema; Epithelial Sodium Channels; Insulin; Kidney; Male; Natriuresis; Oxazoles; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones; Triazoles; Water-Electrolyte Balance

2008
Synthesis of 5-aryl-2H-tetrazoles, 5-aryl-2H-tetrazole-2-acetic acids, and [(4-phenyl-5-aryl-4H-1,2,4-triazol-3-yl)thio]acetic acids as possible superoxide scavengers and antiinflammatory agents.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthus Reaction; Azoles; Biological Assay; Edema; Indicators and Reagents; Magnetic Resonance Spectroscopy; Rats; Spectrophotometry, Infrared; Structure-Activity Relationship; Superoxides; Tetrazoles; Triazoles

1984
In vitro and in vivo activity profile of RHC 2851: a new orally effective antiallergic agent.
    Journal of immunopharmacology, 1983, Volume: 5, Issue:4

    Topics: Anaphylaxis; Animals; Basophils; Carrageenan; Cromolyn Sodium; Edema; Guinea Pigs; Histamine Release; Immunoglobulin E; Intradermal Tests; Ketotifen; Mast Cells; Passive Cutaneous Anaphylaxis; Piperazines; Rats; Triazoles

1983
Substituted triazoles as anti-inflammatory agents.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 45, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry, Physical; Edema; Phenylbutazone; Protease Inhibitors; Rats; Species Specificity; Stomach Ulcer; Triazoles

1984
1-Acyltriazoles as antiinflammatory agents.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthus Reaction; Edema; Ibuprofen; Male; Mice; Structure-Activity Relationship; Triazoles

1982
A study of anti-inflammatory and analgesic activities of some newer triazoles.
    Pharmacological research communications, 1982, Volume: 14, Issue:4

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Drug Evaluation, Preclinical; Edema; Female; Lethal Dose 50; Male; Mice; Peptic Ulcer; Rats; Structure-Activity Relationship; Triazoles

1982
[Study of some derivatives of the benzotriazole nucleus].
    Il Farmaco; edizione scientifica, 1980, Volume: 35, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Central Nervous System Depressants; Edema; Magnetic Resonance Spectroscopy; Mice; Pain; Rats; Triazoles

1980
Inhibition of leukocyte adhesion to endothelial cells of human umbilical vein by Y-24180, an antagonist of platelet-activating factor.
    International journal of immunopharmacology, 1993, Volume: 15, Issue:6

    Topics: Animals; Antigens, CD; Azepines; CD18 Antigens; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; E-Selectin; Edema; Endothelium, Vascular; Guinea Pigs; Humans; Intercellular Adhesion Molecule-1; Leukocytes; Male; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Triazoles; Umbilical Veins

1993
Interleukin-1-induced leukocyte extravasation across rat mesenteric microvessels is mediated by platelet-activating factor.
    Blood, 1995, May-01, Volume: 85, Issue:9

    Topics: Animals; Azepines; Cell Adhesion; Chemotaxis, Leukocyte; Dihydropyridines; Edema; Imidazoles; Inflammation; Interleukin-1; Leukocytes; Male; Mesentery; Microcirculation; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Recombinant Proteins; Skin; Triazoles

1995
Collagenase-induced oedema in the rat paw and the kinin system.
    European journal of pharmacology, 1995, Feb-14, Volume: 274, Issue:1-3

    Topics: Animals; Arginine; Azepines; Bradykinin; Collagenases; Edema; Female; Heparin; Hindlimb; Indomethacin; Kallikrein-Kinin System; Ketoprofen; Kininogens; Male; Methysergide; Nitroarginine; Platelet Aggregation Inhibitors; Pyrilamine; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Triazoles

1995
Protective effect of DS-4574 on gastric mucosal injury induced by acidified ethanol in rats.
    European journal of pharmacology, 1993, Nov-30, Volume: 250, Issue:1

    Topics: Acetophenones; Animals; Autacoids; Cell Degranulation; Edema; Ethanol; Gastric Mucosa; Hydrogen-Ion Concentration; Leukotriene Antagonists; Male; Mast Cells; Necrosis; Pyrimidines; Rats; Rats, Sprague-Dawley; Tetrazoles; Triazoles

1993
Contact sensitivity to Tinuvin P in mice.
    Contact dermatitis, 1994, Volume: 30, Issue:4

    Topics: Animals; Cross Reactions; Dermatitis, Contact; Dermatitis, Irritant; Ear, External; Edema; Female; Lymph Nodes; Mice; Mice, Inbred BALB C; Organ Size; Triazoles

1994
Histologic and ultrastructural changes after large-colon torsion, with and without use of a specific platelet-activating factor antagonist (WEB 2086), in ponies.
    American journal of veterinary research, 1994, Volume: 55, Issue:5

    Topics: Animals; Azepines; Colon; Colonic Diseases; Edema; Epithelium; Female; Horse Diseases; Horses; Intestinal Mucosa; Male; Microscopy, Electron; Necrosis; Neutrophils; Platelet Activating Factor; Torsion Abnormality; Triazoles

1994
Contact sensitivity of and cross-sensitivity between 2-(2'-hydroxy-5'-methylphenyl)benzotriazole (Tinuvin P) and 2-(2'-hydroxy-3'-tert-butyl-5'-methylphenyl)-5-chlorobenzotriazole (Tinuvin 326) evaluated by lymph node cell proliferation and ear swelling r
    Toxicology letters, 1994, Volume: 71, Issue:2

    Topics: Administration, Topical; Animals; Cell Division; Cross Reactions; Dermatitis, Contact; Ear; Edema; Female; Injections, Intradermal; Lymph Nodes; Mice; Mice, Inbred BALB C; Triazoles

1994
1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities.
    Journal of medicinal chemistry, 1993, Jun-25, Volume: 36, Issue:13

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Edema; In Vitro Techniques; Lipoxygenase Inhibitors; Male; ortho-Aminobenzoates; Oxadiazoles; Rats; Rats, Wistar; Structure-Activity Relationship; Thiadiazoles; Triazoles; Tumor Cells, Cultured

1993
Actions of PAF receptor antagonists in horses with the allergic skin disease sweet itch.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:10

    Topics: Animals; Azepines; Ceratopogonidae; Dermatitis, Allergic Contact; Edema; Female; Horse Diseases; Horses; Injections, Intradermal; Injections, Intravenous; Insect Bites and Stings; Male; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pruritus; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles

1995
Priming of eosinophil recruitment in vivo by LPS pretreatment.
    Journal of immunology (Baltimore, Md. : 1950), 1996, Aug-15, Volume: 157, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Azepines; CD18 Antigens; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Complement C5a, des-Arginine; Cycloheximide; Drug Synergism; Edema; Eosinophilia; Eosinophils; Female; Guinea Pigs; Immunoglobulin G; Interleukin 1 Receptor Antagonist Protein; Leukocyte Count; Leukotriene B4; Lipopolysaccharides; Lipoxygenase Inhibitors; Neutrophils; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Protein Synthesis Inhibitors; Pyrans; Quinolones; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Recombinant Fusion Proteins; Sialoglycoproteins; Skin; Triazoles; Zymosan

1996
Synthesis and anti-inflammatory activity of polyazaheterocyclic derivatives of 6-amino-2,4-lutidine and their precursors.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Lethal Dose 50; Male; Pyridines; Rats; Rats, Wistar; Tetrazoles; Triazoles

1997
The pharmacological profile of mouse hind paw inflammation induced by staphylococcal enterotoxin type A.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46, Issue:9

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Azepines; Capsaicin; Cimetidine; Dexamethasone; Diphenhydramine; Edema; Enterotoxins; Enzyme Inhibitors; Hindlimb; Histamine Antagonists; Indomethacin; Inflammation; Male; Mice; Platelet Aggregation Inhibitors; Triazoles

1997
[Synthesis and properties of 5(4,6-diphenyl-2-pyrimidin-2-yl)-1,2,4-triazolin-3-thione and derivatives ].
    Die Pharmazie, 1998, Volume: 53, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Magnetic Resonance Spectroscopy; Pyrimidines; Rats; Rats, Wistar; Triazoles

1998
Nonsteroidal anti-inflammatory activity of 1,2,4-triazolyl-heterocarboxylic derivatives.
    Arzneimittel-Forschung, 1999, Volume: 49, Issue:6

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Bleeding Time; Carboxylic Acids; Carrageenan; Ear, External; Edema; Gossypium; Granuloma; Male; Mice; Pain Measurement; Rats; Rats, Wistar; Stomach Ulcer; Triazoles

1999
Synthesis and evaluation of anti-inflammatory activity of some thiazolo[3,2-b]-1,2,4-triazole-5(6H)-ones and their Michael addition products.
    Arzneimittel-Forschung, 1999, Volume: 49, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Female; Magnetic Resonance Spectroscopy; Male; Mice; Stomach Ulcer; Thiazoles; Triazoles

1999
Bothrops lanceolatus (Fer de lance) venom induces oedema formation and increases vascular permeability in the mouse hind paw.
    Toxicon : official journal of the International Society on Toxinology, 2000, Volume: 38, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Azepines; Capillary Permeability; Crotalid Venoms; Edema; Male; Mice; Triazoles

2000
Synthesis of some thiazolo[3,2-b]-1,2,4-triazole-5(6H)-ones and their novel Michael addition products with anti-inflammatory activities.
    Arzneimittel-Forschung, 2001, Volume: 51, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chemical Phenomena; Chemistry, Physical; Edema; Female; Magnetic Resonance Spectroscopy; Male; Mice; Spectrophotometry, Infrared; Stomach Ulcer; Thiazoles; Triazoles

2001
Synthesis of some new 1-acylthiosemicarbazides, 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazole-3-thiones and their anti-inflammatory activities.
    Arzneimittel-Forschung, 2001, Volume: 51, Issue:6

    Topics: Air; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azides; Carrageenan; Crystallization; Edema; Foot; Male; Mice; Oxadiazoles; Spectrophotometry, Ultraviolet; Thiadiazoles; Triazoles

2001
Synthesis and pharmacological activity of 1,2,4-triazolo[4,3-a]quinolines.
    Farmaco (Societa chimica italiana : 1989), 2001, Volume: 56, Issue:12

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Edema; Female; Isoquinolines; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Structure; Pain; Structure-Activity Relationship; Triazoles

2001
Biocompatibility of thermosensitive chitosan-based hydrogels: an in vivo experimental approach to injectable biomaterials.
    Biomaterials, 2002, Volume: 23, Issue:13

    Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Biocompatible Materials; Bradykinin; Chitin; Chitosan; Diphenhydramine; Edema; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogels; Platelet Aggregation Inhibitors; Rats; Temperature; Time Factors; Triazoles

2002
Synthesis of carboxyalkylthio-triazoles and bicyclic derivatives with antiinflammatory and analgesic activity.
    Farmaco (Societa chimica italiana : 1989), 1992, Volume: 47, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Carrageenan; Edema; Lethal Dose 50; Mice; Pain Measurement; Rats; Structure-Activity Relationship; Superoxides; Thiazoles; Triazoles

1992
The role of complement, platelet-activating factor and leukotriene B4 in a reversed passive Arthus reaction.
    British journal of pharmacology, 1992, Volume: 107, Issue:1

    Topics: Animals; Arthus Reaction; Azepines; Complement System Proteins; Edema; Isoquinolines; Leukotriene B4; Platelet Activating Factor; Rabbits; Radioimmunoassay; Receptors, Complement; Tetrazoles; Triazoles; Zymosan

1992
Homologous tachyphylaxis to bradykinin and its interference with allergic pleurisy in actively sensitized rats.
    European journal of pharmacology, 1992, Sep-10, Volume: 220, Issue:1

    Topics: Amino Acid Sequence; Animals; Azepines; Bradykinin; Diterpenes; Dose-Response Relationship, Drug; Edema; Female; Fibrinolytic Agents; Ginkgolides; Lactones; Leukocyte Count; Male; Molecular Sequence Data; Ovalbumin; Plant Extracts; Pleurisy; Rats; Rats, Wistar; Tachyphylaxis; Triazoles

1992
Differential inhibition by the PAF receptor antagonist, WEB 2170, of allergic inflammation in single sensitized and boosted mice.
    European journal of pharmacology, 1992, Jan-28, Volume: 211, Issue:1

    Topics: Animals; Antigens; Azepines; Dose-Response Relationship, Drug; Edema; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Platelet Activating Factor; Triazoles

1992
Effect of PAF-acether antagonists on active anaphylactic mouse paw edema.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Anaphylaxis; Animals; Aspirin; Azepines; Cimetidine; Dexamethasone; Edema; Male; Meclizine; Methysergide; Mice; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prednisolone; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetrazoles; Triazoles

1991
Inflammatory edema induced by interactions between IL-1 and the neuropeptide calcitonin gene-related peptide.
    Journal of immunology (Baltimore, Md. : 1950), 1991, May-15, Volume: 146, Issue:10

    Topics: Animals; Azepines; Calcitonin Gene-Related Peptide; Capillary Permeability; Complement C5a; Dinoprostone; Drug Synergism; Edema; Histamine H1 Antagonists; In Vitro Techniques; Interleukin-1; Male; Neutrophils; Platelet Activating Factor; Protein Synthesis Inhibitors; Rabbits; Triazoles

1991
Preparation and pharmacological activity of some 1-lupinylbenzimidazoles and 1-lupinylbenzotriazoles.
    Farmaco (Societa chimica italiana : 1989), 1991, Volume: 46, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Diuretics; Edema; Female; Male; Mice; Pregnancy; Quinolizines; Rats; Rats, Inbred SHR; Reaction Time; Spectrophotometry, Ultraviolet; Triazoles

1991
Synthesis and anti-inflammatory and analgesic activity of some 3-(1-adamantyl)-4-substituted-5-mercapto-1,2,4-triazoles.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:12

    Topics: Adamantane; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dose-Response Relationship, Drug; Edema; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Mice; Pain Measurement; Rats; Sulfhydryl Compounds; Triazoles

1991
Enterolobin induces rat paw oedema independently of PAF-acether.
    Memorias do Instituto Oswaldo Cruz, 1991, Volume: 86 Suppl 2

    Topics: Animals; Azepines; Dihydropyridines; Diterpenes; Edema; Ginkgolides; Lactones; Male; Plant Proteins; Platelet Activating Factor; Rats; Rats, Wistar; Triazoles

1991
Airway oedema and obstruction in guinea pigs exposed to inhaled endotoxin.
    British journal of industrial medicine, 1991, Volume: 48, Issue:9

    Topics: Aerosols; Airway Obstruction; Animals; Azepines; Dust; Edema; Endotoxins; Gossypium; Guinea Pigs; Male; Platelet Activating Factor; Respiration Disorders; Triazoles

1991
Bradykinin-induced plasma exudation in guinea-pig airways: involvement of platelet activating factor.
    British journal of pharmacology, 1990, Volume: 101, Issue:3

    Topics: Animals; Azepines; Bradykinin; Edema; Evans Blue; Exudates and Transudates; Guinea Pigs; Male; Plasma; Platelet Activating Factor; Respiratory Physiological Phenomena; Respiratory System; Triazoles

1990
Pharmacological characterization of polycation-induced rat hind-paw oedema.
    British journal of pharmacology, 1990, Volume: 101, Issue:4

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arginine; Azepines; Dexamethasone; Edema; Evans Blue; Heparin; Histamine; Indomethacin; Male; omega-N-Methylarginine; Peptides; Polylysine; Rats; Rats, Inbred Strains; Serotonin; Triazoles

1990
Differential inhibition by two hetrazepine PAF antagonists of acute inflammation in the mouse.
    British journal of pharmacology, 1990, Volume: 99, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Carrageenan; Dose-Response Relationship, Drug; Edema; Exudates and Transudates; Female; Leukocyte Count; Male; Mice; Platelet Activating Factor; Pleurisy; Serotonin; Triazines; Triazoles

1990
Effect of histamine H2-receptor antagonists on acute inflammatory of the rat paw oedema.
    The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cimetidine; Edema; Freund's Adjuvant; Histamine; Histamine H2 Antagonists; Male; Pyrilamine; Ranitidine; Rats; Rats, Inbred Strains; Triazoles

1989
[Studies of the effects of new derivatives of 3-oxo-2,3,5,6,7-8-hexahydro-S-triazolo[4,3-A]pyrimidine on the central nervous system].
    Acta poloniae pharmaceutica, 1988, Volume: 45, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System; Chemical Phenomena; Chemistry; Edema; Male; Mice; Pain; Pyrimidines; Rats; Rats, Inbred Strains; Triazoles

1988
[Investigations on synthesis and antiinflammatory activity of aliphatically substituted benzotriazoles (author's transl)].
    Archiv der Pharmazie, 1974, Volume: 307, Issue:11

    Topics: Anti-Inflammatory Agents; Edema; Triazoles

1974
Experimental antiinflammatory and analgesic studies with 3-trifluoromethyl-s-triazolo (3,4-a)-isoquinoline.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:2

    Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Digestive System; Edema; Female; Fever; In Vitro Techniques; Isoquinolines; Male; Mice; Phenylbutazone; Prostaglandin Antagonists; Prostaglandins; Rats; Reaction Time; Sheep; Triazoles

1974
[Synthesis of potential anti-inflammatory agents of the benztriazole series].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:11

    Topics: Anti-Inflammatory Agents; Edema; Humans; Triazoles

1970