triazoles has been researched along with Brain Ischemia in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (16.67) | 18.2507 |
| 2000's | 15 (50.00) | 29.6817 |
| 2010's | 10 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gu, Y; Liu, J; Zhou, Y | 1 |
| Buendia, I; Casas, AI; Egea, J; Geuss, E; Herrmann, AM; Kleikers, PWM; Kleinschnitz, C; Lopez, MG; Mencl, S; Meuth, SG; Schmidt, HHHW | 1 |
| Gao, A; Gao, J; Gao, L; Hu, Y; Li, J; Pang, T; Ruan, W; Xu, M; Ye, Q; Zhou, Y | 1 |
| Ain-Shoka, AA; Attia, AS; El-Sahar, AE; Safar, MM; Zaki, HF | 1 |
| Liu, B; Lou, Z; Luo, XJ; Ma, QL; Peng, J; Peng, JJ; Ren, KD; Ren, X; Tan, B; Yang, J; Yang, ZB | 1 |
| Abdel-Rahman, AA; Agha, AM; Mohamed, RA; Nassar, NN | 1 |
| Chen, JW; Dai, G; Feng, L; Li, MC; Li, SL; Liu, Z; Shi, ZS; Tuo, YH; Wang, JS; Wang, QY; Zhang, YL | 1 |
| Chen, JW; Dai, G; Feng, L; Li, MC; Li, S; Liu, Z; Shi, ZS; Tuo, YH; Wang, JS; Wang, QY; Zhang, YL | 1 |
| Bari, F; Farkas, E; Hertelendy, P; Ivánkovits-Kiss, O; Menyhárt, Á; Puskás, T; Tóth, R; Varga, DP; Zölei-Szénási, D | 1 |
| Deng, YL; Guo, H; Hou, WG; Hou, YS; Liu, Y; Ma, YL; Miao, Y; Qin, P; Wang, LY; Zhang, LX; Zhang, ZL | 1 |
| Catarzi, D; Ciampi, O; Colotta, V; Filacchioni, G; Lenzi, O; Martini, C; Morizzo, E; Moro, S; Pedata, F; Pugliese, AM; Traini, C; Trincavelli, L; Varano, F | 2 |
| Bruni, P; Cipriani, S; Donati, C; Giovannini, MG; Melani, A; Nosi, D; Pedata, F; Vannucchi, MG | 1 |
| Cipriani, S; Galli, A; Gianfriddo, M; Giovannini, MG; Mello, T; Pedata, F; Pugliese, AM; Traini, C | 1 |
| Bertorelli, R; Bianchi, L; Bordoni, F; Gianfriddo, M; Melani, A; Monopoli, A; Pantoni, L; Pedata, F; Vannucchi, MG | 1 |
| Kadaba, PK | 1 |
| Corradetti, R; Latini, S; Pedata, F; Pugliese, AM | 1 |
| Bonfanti, A; Chiaramonte, G; Marcoli, M; Maura, G; Ongini, E; Raiteri, M; Roccatagliata, P | 1 |
| Coppi, E; Corradetti, R; Pedata, F; Pugliese, AM; Spalluto, G | 1 |
| Baraldi, PG; Cipriani, S; Gianfriddo, M; Giovannini, MG; Melani, A; Pedata, F; Vannucchi, MG | 1 |
| Behan, WM; Stone, TW | 1 |
| Gao, Y; Phillis, JW | 1 |
| Ikeda, M; Kihara, T; Kogure, K; Matsuo, Y; Ninomiya, M; Onodera, H | 1 |
| Adén, U; Bona, E; Fredholm, BB; Gilland, E; Hagberg, H | 1 |
| Abbracchio, MP; Cattabeni, F | 1 |
| Barks, JD; Eun, BL; Liu, XH | 1 |
| Ciceri, P; Monopoli, A; Nicosia, S; Rabuffetti, M | 1 |
| Bernardi, G; Calabresi, P; Centonze, D; Pisani, A; Saulle, E | 1 |
| Blasevich, M; Galli, C; Papini, N; Petroni, A | 1 |
| O'Regan, MH; Perkins, LM; Phillis, JW; Simpson, RE | 1 |
1 review(s) available for triazoles and Brain Ischemia
| Article | Year |
|---|---|
Rational drug design and the discovery of the delta2-1,2,3-triazolines, a unique class of anticonvulsant and antiischemic agents.
Topics: Animals; Anticonvulsants; Brain Ischemia; Drug Design; Epilepsy; Humans; Pharmacokinetics; Stroke; Structure-Activity Relationship; Triazoles | 2003 |
29 other study(ies) available for triazoles and Brain Ischemia
| Article | Year |
|---|---|
BRD4 suppression alleviates cerebral ischemia-induced brain injury by blocking glial activation via the inhibition of inflammatory response and pyroptosis.
Topics: Animals; Azepines; Brain Injuries; Brain Ischemia; Cell Survival; Cells, Cultured; Inflammation; Male; Mice; Mice, Inbred C57BL; Neuroglia; Nuclear Proteins; Pyroptosis; Transcription Factors; Triazoles | 2019 |
NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage.
Topics: Animals; Benzoxazoles; Blood-Brain Barrier; Brain; Brain Ischemia; Endothelial Cells; Enzyme Inhibitors; Female; Femoral Artery; Gene Expression Regulation; Hindlimb; Humans; Male; Mice; Mice, Knockout; Myocardial Ischemia; NADPH Oxidase 4; Neurons; Neuroprotective Agents; Organ Specificity; Pyrazoles; Pyridones; Rats; Signal Transduction; Triazoles | 2017 |
Synthesis and biological evaluation of novel 4,5-bisindolyl-1,2,4-triazol-3-ones as glycogen synthase kinase-3β inhibitors and neuroprotective agents.
Topics: Animals; Brain Ischemia; Computer Simulation; Glycogen Synthase Kinase 3 beta; In Vitro Techniques; Neurons; Neuroprotective Agents; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Stroke; Structure-Activity Relationship; Triazoles | 2017 |
Sitagliptin attenuates transient cerebral ischemia/reperfusion injury in diabetic rats: implication of the oxidative-inflammatory-apoptotic pathway.
Topics: Animals; Brain Ischemia; Caspase 3; Cytochromes c; Diabetes Complications; Diabetes Mellitus, Experimental; Hippocampus; Hypoglycemic Agents; Interleukin-10; Male; Neuroprotective Agents; Neutrophil Infiltration; Pyrazines; Rats; Rats, Wistar; Reperfusion Injury; Sitagliptin Phosphate; Triazoles | 2015 |
Salviaolate Protects Rat Brain from Ischemia-Reperfusion Injury through Inhibition of NADPH Oxidase.
Topics: Animals; Antioxidants; Benzofurans; Benzoxazoles; Brain; Brain Ischemia; Cells, Cultured; China; Cinnamates; Depsides; Disease Models, Animal; Drugs, Chinese Herbal; Male; NADPH Oxidases; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Rosmarinic Acid; Salvia miltiorrhiza; Triazoles | 2015 |
Role of adenosine A2A receptor in cerebral ischemia reperfusion injury: Signaling to phosphorylated extracellular signal-regulated protein kinase (pERK1/2).
Topics: Adenosine A2 Receptor Antagonists; Animals; Apoptosis; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cyclic AMP; Flavonoids; Hippocampus; Inflammation Mediators; Male; MAP Kinase Signaling System; Maze Learning; Microglia; Motor Activity; Phosphorylation; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Reperfusion Injury; Triazoles | 2016 |
NADPH oxidase inhibitor improves outcome of mechanical reperfusion by suppressing hemorrhagic transformation.
Topics: Animals; Benzoxazoles; Brain Ischemia; Cerebral Hemorrhage; Male; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion; Reperfusion Injury; Thrombectomy; Treatment Outcome; Triazoles | 2017 |
NADPH oxidase inhibitor regulates microRNAs with improved outcome after mechanical reperfusion.
Topics: Animals; Benzoxazoles; Brain Ischemia; Infarction, Middle Cerebral Artery; Male; MicroRNAs; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Reperfusion; Treatment Outcome; Triazoles | 2017 |
Contribution of prostanoid signaling to the evolution of spreading depolarization and the associated cerebral blood flow response.
Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Laser-Doppler Flowmetry; Male; Nitrobenzenes; Prosencephalon; Prostaglandins; Pyrazoles; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides; Thiophenes; Triazoles | 2016 |
Alleviation of ischaemia-reperfusion injury by endogenous estrogen involves maintaining Bcl-2 expression via the ERα signalling pathway.
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Estradiol; Estrogen Receptor alpha; Estrogens; Estrous Cycle; Female; Genes, bcl-2; Infarction, Middle Cerebral Artery; Letrozole; Neurons; Neuroprotective Agents; Nitriles; Ovariectomy; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Triazoles | 2017 |
Pyrido[2,3-e]-1,2,4-triazolo[4,3-a]pyrazin-1-one as a new scaffold to develop potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.
Topics: Adenosine A3 Receptor Antagonists; Animals; Brain Ischemia; Cattle; Cell Line; Cerebral Cortex; Corpus Striatum; Cricetinae; Cricetulus; Cyclic AMP; Heterocyclic Compounds, 3-Ring; Hippocampus; Humans; Hydrogen Bonding; In Vitro Techniques; Ligands; Male; Models, Molecular; Pyrazines; Pyridines; Radioligand Assay; Rats; Rats, Wistar; Structure-Activity Relationship; Synaptic Transmission; Triazoles | 2009 |
Selective adenosine A2a receptor antagonism reduces JNK activation in oligodendrocytes after cerebral ischaemia.
Topics: Adenosine A2 Receptor Antagonists; Animals; Basic Helix-Loop-Helix Transcription Factors; Brain Ischemia; Corpus Striatum; Drug Evaluation, Preclinical; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Male; Microglia; Motor Activity; Myelin Sheath; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Oligodendrocyte Transcription Factor 2; Oligodendroglia; Pyrimidines; Rats; Rats, Wistar; Triazoles | 2009 |
The adenosine A2A receptor antagonist ZM241385 enhances neuronal survival after oxygen-glucose deprivation in rat CA1 hippocampal slices.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Astrocytes; Blotting, Western; Brain Ischemia; Cell Hypoxia; Cell Survival; Coloring Agents; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Glucose; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Neurons; Neuroprotective Agents; Oxygen; Phenethylamines; Propidium; Pyrazoles; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Staining and Labeling; Time Factors; Triazines; Triazoles | 2009 |
The selective A2A receptor antagonist SCH 58261 reduces striatal transmitter outflow, turning behavior and ischemic brain damage induced by permanent focal ischemia in the rat.
Topics: Animals; Brain Ischemia; Corpus Striatum; Male; Motor Activity; Neurotransmitter Agents; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazoles | 2003 |
Brief, repeated, oxygen-glucose deprivation episodes protect neurotransmission from a longer ischemic episode in the in vitro hippocampus: role of adenosine receptors.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Animals; Brain Ischemia; Electric Stimulation; Excitatory Postsynaptic Potentials; Glucose; Hippocampus; Hypoxia; In Vitro Techniques; Ischemic Preconditioning; Male; Oxygen; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Synaptic Transmission; Time Factors; Triazines; Triazoles; Xanthines | 2003 |
Glutamate efflux from human cerebrocortical slices during ischemia: vesicular-like mode of glutamate release and sensitivity to A(2A) adenosine receptor blockade.
Topics: Adenosine A2 Receptor Antagonists; Adult; Aged; Anesthetics, Local; Aspartic Acid; Brain Ischemia; Calcium; Cerebral Cortex; Female; Glucose; Glutamic Acid; Humans; In Vitro Techniques; Male; Middle Aged; Neuroprotective Agents; Pyrimidines; Reperfusion Injury; Synaptic Vesicles; Tetrodotoxin; Triazoles | 2004 |
A3 adenosine receptor antagonists delay irreversible synaptic failure caused by oxygen and glucose deprivation in the rat CA1 hippocampus in vitro.
Topics: Action Potentials; Adenosine A3 Receptor Antagonists; Animals; Brain Ischemia; Hippocampus; Hypoglycemia; Hypoxia; Male; Pyridines; Quinazolines; Rats; Rats, Wistar; Receptor, Adenosine A3; Synaptic Transmission; Time Factors; Triazoles | 2006 |
The selective A2A receptor antagonist SCH 58261 protects from neurological deficit, brain damage and activation of p38 MAPK in rat focal cerebral ischemia.
Topics: Analysis of Variance; Animals; Blotting, Western; Brain; Brain Injuries; Brain Ischemia; Disease Models, Animal; Enzyme Activation; Functional Laterality; Immunohistochemistry; Male; Microscopy, Confocal; Motor Activity; Nervous System Diseases; Neurologic Examination; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Pyrimidines; Rats; Rats, Wistar; Triazoles | 2006 |
Interleukin-1beta but not tumor necrosis factor-alpha potentiates neuronal damage by quinolinic acid: protection by an adenosine A2A receptor antagonist.
Topics: Adenosine A2 Receptor Antagonists; Animals; Brain Injuries; Brain Ischemia; Cytoprotection; Drug Synergism; Hippocampus; Interleukin-1beta; Male; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Pyramidal Cells; Quinolinic Acid; Rats; Rats, Wistar; Receptor, Adenosine A2A; Triazines; Triazoles; Tumor Necrosis Factor-alpha | 2007 |
Synthesis, ligand-receptor modeling studies and pharmacological evaluation of novel 4-modified-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives as potent and selective human A3 adenosine receptor antagonists.
Topics: Adenosine A3 Receptor Antagonists; Animals; Binding, Competitive; Brain Ischemia; Cattle; Cell Membrane; Cerebral Cortex; Disease Models, Animal; Humans; Hydrogen Bonding; Ligands; Models, Molecular; Protein Binding; Quinoxalines; Rats; Receptor, Adenosine A3; Rhodopsin; Structural Homology, Protein; Structure-Activity Relationship; Triazoles; Xanthines | 2008 |
CGS 15943, an adenosine A2 receptor antagonist, reduces cerebral ischemic injury in the Mongolian gerbil.
Topics: Animals; Brain Ischemia; Gerbillinae; Male; Motor Activity; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Quinazolines; Triazoles | 1994 |
Role of platelet-activating factor and thromboxane A2 in radical production during ischemia and reperfusion of the rat brain.
Topics: Animals; Ascorbic Acid; Azepines; Brain; Brain Ischemia; Bridged Bicyclo Compounds; Dehydroascorbic Acid; Extracellular Space; Fatty Acids, Monounsaturated; Free Radicals; Male; Oxygen; Partial Pressure; Peroxidase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion; Thromboxane A2; Triazoles | 1996 |
Neonatal cerebral hypoxia-ischemia: the effect of adenosine receptor antagonists.
Topics: Animals; Animals, Newborn; Blood Gas Analysis; Blood Glucose; Body Temperature; Body Weight; Brain; Brain Ischemia; Cerebrovascular Circulation; Female; Hypoxia, Brain; Male; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; RNA, Messenger; Theophylline; Triazoles; Xanthines | 1997 |
Brain adenosine receptors as targets for therapeutic intervention in neurodegenerative diseases.
Topics: Adenosine; Animals; Astrocytes; Brain Infarction; Brain Ischemia; Cell Death; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles | 1999 |
Platelet-activating factor antagonist BN 50730 attenuates hypoxic-ischemic brain injury in neonatal rats.
Topics: Animals; Animals, Newborn; Azepines; Brain Injuries; Brain Ischemia; Cerebral Cortex; Corpus Striatum; Hippocampus; Hypoxia, Brain; Learning; Memory; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thienopyridines; Triazoles | 2001 |
Production of leukotrienes in a model of focal cerebral ischaemia in the rat.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Cysteine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Indoles; Leukotrienes; Lipoxygenase Inhibitors; Male; Neuroprotective Agents; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Triazoles | 2001 |
Adenosine-mediated inhibition of striatal GABAergic synaptic transmission during in vitro ischaemia.
Topics: Adenosine; Adenosine Triphosphate; Animals; Brain Ischemia; Corpus Striatum; gamma-Aminobutyric Acid; Male; Membrane Potentials; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Potassium Channels; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synaptic Transmission; Triazines; Triazoles; Xanthines | 2001 |
Blockade of A(2A) adenosine receptors leads to c-fos inhibition in a rat model of brain ischemia.
Topics: Animals; Blotting, Western; Brain Ischemia; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Male; Proto-Oncogene Proteins c-fos; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Triazoles | 2002 |
Excitatory transmitter amino acid release from the ischemic rat cerebral cortex: effects of adenosine receptor agonists and antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Glutamates; Glutamic Acid; Male; Neurotransmitter Agents; Purinergic Antagonists; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Triazoles; Xanthines | 1992 |