triazoles has been researched along with Benign Neoplasms in 313 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (5.11) | 18.7374 |
| 1990's | 12 (3.83) | 18.2507 |
| 2000's | 53 (16.93) | 29.6817 |
| 2010's | 170 (54.31) | 24.3611 |
| 2020's | 62 (19.81) | 2.80 |
| Authors | Studies |
|---|---|
| Li, X; Li, Y; Luo, Y; Wang, Y; Wu, J; Yan, P; Zhou, S | 1 |
| Ahnert, JR; Albittar, AA; Dalal, S; Dev, R; Fu, S; Hui, D; Karp, DD; Liu, S; Meric-Bernstam, F; Naing, A; Piha-Paul, SA; Rubin, L; Tsimberidou, AM; Yap, TA; Zarifa, A; Zhong, LL | 1 |
| Alam, MM | 1 |
| Carter, BW; Colen, R; Fu, S; Gong, J; Hong, DS; Janku, F; Karp, DD; McQuinn, L; Meric-Bernstam, F; Milton, DR; Naing, A; Piha-Paul, SA; Shah, J; Stephen, BA; Sulovic, S; Thein, KZ; Tsimberidou, A; Yap, TA | 1 |
| Al Shareef, ZM; El-Sadek, M; Hamdy, R; Hamoda, AM; Jones, AT; Shakartalla, SB; Soliman, SSM; Westwell, AD | 1 |
| Lei, Y; Li, J; Li, X; Luo, Y; Ni, D; Peng, P; Sun, H; Wang, X; Yu, T | 1 |
| Faiz, S; Irfan, A; Kotwica-Mojzych, K; Mojzych, M; Rasul, A; Zafar, R; Zahoor, AF | 1 |
| Bhandare, RR; Natarajan, R; Shaik, AB; Sivaperuman, A; Subramani, AK | 1 |
| Belotti, T; Campoli, C; Cojutti, PG; Gatti, M; Masetti, R; Pea, F; Pession, A; Viale, P | 1 |
| Deycmar, S; Georg, D; Kerschbaum-Gruber, S; Mara, E; Pruschy, M; Waller, V | 1 |
| Sachdeva, H; Saquib, M; Tanwar, K | 1 |
| Chen, A; Li, X; Si, H; Xuan, B; Yang, W | 1 |
| Ding, K; Duan, L; Fu, R; Guo, Y; Liu, Z; Shen, H | 1 |
| Ali, A; Asati, V; Dhiman, S; Gupta, GD; Saha, M | 1 |
| Kumar, K; Rathod, B | 1 |
| Ganipisetti, H; Kumar Putta, VN; Majhi, D; Mallisetty, NM; Sirisilla, R | 1 |
| Arslan, M; Beydemir, Ş; Demir, Y; Güleç, Ö; Kakakhan, C; Özkemahlı, G; Türkeş, C | 1 |
| Chen, R; Huo, L; Jaiswal, Y; Jia, Z; Liang, Y; Liu, X; Lu, R; Nong, Y; Williams, L; Xu, H | 1 |
| Cornely, OA; Franz, J; Jakobs, F; Jeck, J; Kron, A; Kron, F; Wingen-Heimann, SM | 1 |
| Dai, XJ; Gao, Y; Ji, SK; Liu, HM; Xue, LP; Zheng, YC; Zhou, Y | 1 |
| Liu, J; Lv, Z; Xu, Z; Zhang, G; Zhao, S | 1 |
| Abd-Eldayem, MA; Cavalu, S; Hasan, AM; Saber, S; Yahya, G; Youssef, ME | 1 |
| Das, A; Dev Sarma, H; Kumar Sharma, A; Mukherjee, A; Satpati, D; Sharma, R | 1 |
| Deng, P; Gong, X; Liu, X; Mao, L; Shi, L; Shi, W; Sun, B; Sun, X; Zhou, Y | 1 |
| Agarwal, DS; Beteck, RM; Legoabe, LJ; Sakhuja, R | 1 |
| Arya, P; Giovannuzzi, S; Kumar, R; Raghav, N; Sharma, PK; Supuran, CT; Vats, L | 1 |
| Alisi, MA; Aprile, S; Clemente, N; Colombo, G; Galli, U; Genazzani, AA; Grosa, G; Mattoteia, D; Polenzani, L; Scanziani, E; Terrazzino, S; Travelli, C; Tron, GC | 1 |
| Azad, R; Deshmukh, TR; Lokwani, DK; Sarkate, AP; Shingate, BB; Tiwari, SV | 1 |
| Liu, Y; Xu, Z; Zhao, SJ | 1 |
| Chen, J; Chen, Z; Deng, W; Fong, LWR; Hung, MC; Jiang, W; Li, N; Li, X; Lin, SH; Neri, S; Qiao, Y; Stephan, C; Wang, Y; Ye, R; Yu, Y; Zhang, S; Zhen, Y | 1 |
| Cubo, L; Faraco, EJ; Herrero, JM; Matesanz, AI; Quiroga, AG | 1 |
| Aboagye, EO; Årstad, E; Carroll, L; Diocou, S; Gendron, T; Glaser, M; Pedley, RB; Rajkumar, V; Sander, K; Sin, PKB; Witney, TH; Yan, R | 1 |
| Barratt, DG; Beattie, D; Cadogan, EB; Davies, BR; Dean, E; Fallan, C; Finlay, MRV; Goldberg, FW; Howard, MR; Lamont, GM; Ramos-Montoya, A; Schimpl, M; Ting, AKT; Vazquez-Chantada, M; Williamson, B; Wrigley, GL | 1 |
| Hu, LL; Lin, XH; Liu, M; Liu, WJ; Lu, W; Tang, SW; Wang, PL; Wang, W; Wang, X; Yang, JJ; Yu, WW; Zhang, HK; Zhang, Q | 1 |
| Deng, W; Jiang, G; Liu, Y; Wang, C | 1 |
| Duan, WG; Li, FY; Li, QM; Lin, GS; Lu, SZ; Zhu, XP | 1 |
| Alishah, K; Fallah-Mehrjardi, K; Hadjati, J; Jafarzadeh, L; Khakpoor-Koosheh, M; Masoumi, E; Meshkani, R; Mirzaei, HR; Noorbakhsh, F; Rostamian, H | 1 |
| Chen, E; Chen, W; Chen, X; Huang, D; Qian, H; Qiao, H; Tang, Q; Wang, Q; Zhang, J; Zhong, Y | 1 |
| Behe, M; Grob, NM; Mindt, TL; Schibli, R; Schmid, S | 1 |
| Duan, HC; Gan, Y; Hu, JP; Hu, YC; Liang, L; Liu, W; Liu, XY; Luo, Q; Peng, LX; Shi, HB; Sun, X; Wan, H; Zhao, G | 1 |
| Bálint, E; Hackler, L; Kari, B; Puskás, LG; Szabó, PT; Tóth, E; Tripolszky, A | 1 |
| Bernardo, V; Fernandez, AJ; Liverman, R; Miles, A; Tippett, A; Yildirim, I | 1 |
| Al Kafri, N; Hafizi, S | 1 |
| Belskaya, NP; Kostova, IP; Palafox, MA; Slavova, KI; Todorov, LT | 1 |
| Matiadis, D; Sagnou, M | 1 |
| Athavale, M; Kharkar, PS; Padhariya, KN; Srivastava, S | 1 |
| Bazgir, A; Mamaghani, MB; Nazari, S; Safari, F | 1 |
| Dehaen, W; Li, Y; Wang, R | 1 |
| Abbattista, MR; Ackerley, DF; Ashoorzadeh, A; Biemans, R; Copp, JN; Dubois, LJ; Guise, CP; Lambin, P; Lieuwes, NG; Mowday, AM; Patterson, AV; Smaill, JB; Syddall, SP; Theys, J; Wang, J; Williams, EM | 1 |
| Bourque, MS; Bragg, AW; Carias, DC; Cheng, C; Greene, WL; Lambrix, AA; Maron, G; Pauley, JL; Swanson, HD; Zhou, Y | 1 |
| Chen, Y; Jin, H; Li, J; Lu, Z; Mi, Y; Qiao, J; Wang, L; Wang, Q; Zou, Z | 1 |
| Chen, P; Diao, P; Hu, M; Huo, X; Li, Y; Ma, W; Ma, Y; Yang, F; You, W; Zhao, P; Zheng, S | 1 |
| Chen, BF; He, Y; He, ZD; Huang, YZ; Tu, B; Wang, HR; Wang, YH; Zhang, M; Zhu, SQ | 1 |
| Alas, M; Kaur, K; Saghaeidehkordi, A | 1 |
| Correia, JDG; Feige, MJ; Gronauer, TF; Jakob, CHG; Kühn, FE; Meighen-Berger, K; Schlagintweit, JF; Sieber, SA; Weigert Muñoz, A; Weiß, V | 1 |
| Bean, S; Carter, BW; Colen, R; Gong, J; Janku, F; Karp, DD; McQuinn, L; Meric-Bernstam, F; Milton, DR; Naing, A; Ogbonna, DC; Pant, S; Piha-Paul, SA; Shah, J; Subbiah, V; Thein, KZ; Tsimberidou, A; Zarifa, A | 1 |
| Bickerton, SJ; Cadogan, EB; Davies, BR; Dovedi, SJ; Farrington, PM; Hughes, GD; Illidge, TM; James, NH; Karmokar, A; Nakamura, K; Ramos-Montoya, A; Valge-Archer, V | 1 |
| Ghosh, S; Jha, A; Ramarao, TA; Samanta, PK; Satpati, P; Sen, A | 1 |
| Gong, W; Kleist, C; Müller-Tidow, C; Neuber, B; Ni, M; Sauer, T; Schmitt, A; Schmitt, M; Schubert, ML; Sellner, L; Stock, S; Wang, L; Wang, S; Yao, H | 1 |
| Alozie, CO; Casas, S; De Castro, M; DeRose, NK; Dominguez, D; Elshaer, MR; Garton, CS; Gucwa, AL; Lehr, AL; Padilla, AD; Turbi-Henderson, ML; Twining, SD | 1 |
| Chen, W; Chen, X; Guo, X; Jiang, Z; Li, D; Long, G; Wang, X; You, Q | 1 |
| Amanati, A; Badiee, P; Ghasemi, F; Haghpanah, S; Hamzavi, SS; Jafarian, H; Nematolahi, S | 1 |
| Auhmani, A; Bimoussa, A; El Mansouri, AE; Fawzi, M; Laamari, Y; Morjani, H; Oubella, A; Riahi, A; Robert, A; Youssef Ait Itto, M | 1 |
| Ghaedi, K; Majd, A; Miralaei, N; Peymani, M; Safaei, M | 1 |
| Ban, M; Bansode, S; Biradar, S; Gaikwad, NB; Godugu, C; Srinivas, N; Yaddanapudi, VM | 1 |
| Alaoui, S; Auberger, P; Benhida, R; Bougrin, K; Demange, L; Driowya, M; Dufies, M; Pagès, G; Robert, G | 1 |
| Chen, H; Li, X; Rong, R; Wang, B; Wang, Y; Zhu, M | 1 |
| Baburajeev, CP; Barash, U; Bender, A; Fuchs, JE; Mason, DJ; Mohan, CD; Rangappa, KS; Rangappa, S; Vlodavsky, I | 1 |
| Ando, A; Baba, Y; Ebara, S; Hara, T; Kitazawa, S; Satomi, Y; Soga, T | 1 |
| Kahveci, B; Menteşe, E; Ülker, S; Yılmaz, F | 1 |
| Amore, BM; Doi, T; Go, N; Jung, AS; Yang, H; Yasui, H | 1 |
| Baleja, JD; Degterev, A; Dutta, I; Jhaveri, A; Pattni, BS; Torchilin, V | 1 |
| Bedoschi, G; Emirdar, V; Moy, F; Oktay, K; Turan, V | 1 |
| Cohen, N; Hsu, M; Kussin, ML; Liu, D; Mathew, S; Pozotrigo, M; Seo, SK; Seyboth, B; Thackray, J; Yan, SQ | 1 |
| Ali, I; Choi, G; Go, A; Lee, J; Lee, K | 1 |
| Ahangarkani, F; Aslani, N; Badali, H; Boekhout, T; Hagen, F; Kolecka, A; Meis, JF; Meyabadi, MF; Shokohi, T | 1 |
| Blotner, S; Chen, LC; Ejadi, S; Miller, W; Nemunaitis, J; Nichols, G; Razak, A; Vazvaei, F; Young, A; Zhi, J | 1 |
| Geng, J; Li, Y; Najafov, A; Ofengeim, D; Ouchida, AT; Sun, X; Yu, Q; Yuan, J | 1 |
| Adjei, AA; Bishop, WR; Carr, D; Chun, P; Cooper, A; Dayananth, P; Deng, Y; Flaherty, KT; Fong, PC; Hwu, WJ; Kirschmeier, P; Long, BJ; Miselis, NR; Moreno, BH; Moschos, SJ; Ramanathan, RK; Ribas, A; Robert, L; Rubin, EH; Rubino, J; Rush, TS; Samatar, AA; Schiller, J; Shapira-Frommer, R; Shipps, GW; Sullivan, RJ; Tawbi, HA; Zhang, D | 1 |
| Arai, S; Goto, A; Hata, C; Honda, Y; Ichikawa, Y; Kessoku, T; Komori, T; Kusakabe, A; Matsuura, T; Miyashita, Y; Nakajima, A; Saito, Y; Sukegawa, A; Yashiro, R; Yoshida, H; Yoshimi, A | 1 |
| Alhusban, M; Chaurasiya, ND; Chittiboyina, AG; Haider, S; Khan, IA; Tekwani, BL | 1 |
| A Shams El-Dine, SE; Abd El Razik, HA; Abu-Serie, MM; Afifi, OS; Ashour, FA; El-Tombary, AA; Shaaban, OG | 1 |
| Chen, AP; Do, K; Doroshow, JH; Juwara, L; Kummar, S; Meehan, R; O'Sullivan Coyne, G; Rubinstein, L; Zlott, J | 1 |
| Ban, Q; Kong, J; Sun, W; Wu, S | 1 |
| Böttcher, T; Carmo, AML; da Silva, AD; de Souza-Fagundes, EM; Delp, J; Glanzmann, N; Kisitu, J; Leist, M; Marques, LB; Prazeres, PDM; Stroppa, PHF; Szamosvàri, D | 1 |
| Hassan, RA; Kassab, AE | 1 |
| Alvarez Abreu, P; Cabral, LM; Cláudio Rodrigues Pereira da Silva, L; Costa, DCS; da Silva, FC; de Almeida, GS; Ferreira, VF; Rabelo, VW; Sathler, PC | 1 |
| Burke, RT; Doak, AE; Marcus, JM; Orth, JD; Park, S | 1 |
| Abbas Bukhari, SN; Abdel-Aziz, M; Abdel-Rahman, HM; Abdelazeem, AH; El-Sherief, HAM; Youssif, BGM | 1 |
| Bajpai, R; Hall, WD; Lonial, S; Qian, G; Shanmugam, M; Sun, SY; Yao, W; Zhang, S | 1 |
| Chen, J; Gong, W; Liu, B; Liu, C; Shi, X; Wu, X | 1 |
| Günther, S; Mishra, P; Pervaiz, M | 1 |
| Dang Thi, TA; Dinh, TV; Hoang Thi, P; Le Duc, T; Le Thi, TA; Le-Nhat-Thuy, G; Nguyen Quang, H; Nguyen Thanh, P; Nguyen Thi, N; Nguyen, HT; Nguyen, TV; Pham-The, H | 1 |
| Borad, M; Gulbo, J; Mansfield, AS; Mody, K; Nygren, P; Vemireddy, L | 1 |
| Abdouni, H; Bandeira, N; Filippakopoulos, P; Fujisawa, T; Gingras, AC; Gonzalez-Badillo, B; Gupta, GD; Hou, H; Knight, JDR; Lambert, JP; Lin, ZY; Newman, JA; Pelletier, L; Picaud, S; Savitsky, P; St-Denis, N; Stucki, M; Tucholska, M; Uusküla-Reimand, L; Wilson, MD | 1 |
| Cao, D; Chen, D; Chen, L; Chen, Y; Geng, M; Huang, M; Li, J; Li, Y; Lian, F; Meng, T; Shen, J; Wang, X; Xiong, B; Zhang, N | 1 |
| Ballatore, C; Brunden, KR; Francisco, KR; Lucero, B; Oukoloff, K | 1 |
| Cao, J; Chen, T; Dong, H; Kong, X; Ran, Y; Xu, W; Zang, J; Zhang, Y; Zhao, C | 1 |
| Chacón-Huete, F; Chen, F; Covone, J; Forgione, P; Kwan, DH; Petrella, A; Tsai, TW; Yu, CC; Zhang, X | 1 |
| Hong, SH; You, JS | 1 |
| Jain, A; Piplani, P | 1 |
| Arrieta, AC; Bradley, JS; Carmelitano, P; Gates, D; Groll, AH; Joshi, A; Kartsonis, NA; Lehrnbecher, T; Mangin, E; Paschke, A; Sung, L; Walsh, TJ; Waskin, H; Zwaan, CM | 1 |
| Fang, Y; He, Z; Huang, Y; Tang, Y; Wang, B; Wang, H; Xu, Q; Zhang, M | 1 |
| Chen, R; Gao, H; Guo, J; Guo, Y; Jin, H; Li, H; Liu, K; Liu, Y; Qian, Y; Wan, Y; Yang, F; Zhang, C; Zhou, Z | 1 |
| Ahmed, G; Ahmed, N; El-Mahallawy, H; Hafez, H; Hassanain, O; Khedr, R; Madney, Y; Taha, H; Youssef, A | 1 |
| Pang, D; Sui, S; Wang, P; Wang, Q; Xu, S; Zhang, J | 1 |
| Chun, HB; Durden, DL; Garlich, JR; Glass, CK; Joshi, S; Liu, KX; Morales, GA; Pham, TV; Singh, AR; Skola, D; Zulcic, M | 1 |
| Chien, HC; Colas, C; Giacomini, KM; Hall, C; Schlessinger, A; Thomas, AA; Wells, A; Wolfe, H | 1 |
| Chen, Q; Huang, W; Jiang, X; Jiang, Z; Liu, Z; Qiu, Q; Xu, J; Xu, X; Ye, J; Zhu, J | 1 |
| Bauer, TM; Clarke, JM; Hwang, S; Jung, SY; Keedy, VL; Kim, SJ; Lee, H; Lee, JI; Park, N | 1 |
| Duan, W; Luo, C; Shao, J; Tao, H; Yan, X; Zhang, H; Zhu, K | 1 |
| Baraniak, D; Baranowski, D; Boryski, J; Framski, G; Ruszkowski, P | 1 |
| Dillon, KE; Dokras, A; Efymow, BL; Gracia, CR; Johnson, LN; Mainigi, MA; Sammel, MD | 1 |
| Bradley, R; Chen, Y; El-Hariry, I; Goldman, JW; Gordon, GA; Guo, W; Inoue, T; Karol, MD; Raju, RN; Rosen, LS; Teofilivici, F; Vukovic, VM | 1 |
| Bradner, JE; Hoke, HA; Lau, A; Lee, TI; Lin, CY; Lovén, J; Orlando, DA; Vakoc, CR; Young, RA | 1 |
| Stower, H | 1 |
| Adamaki, M; Athanasiadou, A; Ktena, YP; Lambrou, G; Moschovi, M | 1 |
| He, LQ; Jiang, AQ; Liu, ZJ; Luo, Y; Yang, YH; Zhang, S; Zhu, HL | 1 |
| Bradner, J; Chen, LF; Huang, B; Nair, S; Qi, J; Wu, X; Zhang, H; Zou, Z | 1 |
| Bedford, MR; Ford, SJ; Horniblow, RD; Iqbal, TH; Tselepis, C | 1 |
| Amanlou, M; Arabzadeh, AJ; Ardestani, MS; Delbaz, SA; Ebrahimi, SE; Javidi, A; Mahian, H; Rad, AM | 1 |
| Bauman, A; Kluba, CA; Mindt, TL; Valverde, IE; Vomstein, S; Walter, MA | 1 |
| Barrett, K; Berry, M; Blair, WS; Chang, C; Chen, JZ; Cyrus Khojasteh, S; Eigenbrot, C; Ghilardi, N; Gibbons, P; He, H; Hurley, CA; Kenny, JR; Le, H; Lee, L; Liu, W; Lyssikatos, JP; Magnuson, S; Pastor, R; Pulk, R; Sampath, D; Siu, M; Tsui, V; Ultsch, M; Xiao, Y; Zhu, BY | 1 |
| Li, W; Wu, L; Zhang, C | 1 |
| Lopez, C; Pertino, MW; Schmeda-Hirschmann, G; Theoduloz, C | 1 |
| Böhme, A; Buchheidt, D; Cornely, OA; Egerer, G; Heinz, W; Krüger, W; Link, H; Maschmeyer, G; Mousset, S; Neumann, S; Ostermann, H; Panse, J; Penack, O; Rieger, C; Ruhnke, M; Schmidt-Hieber, M; Silling, G; Südhoff, T; Ullmann, AJ; Wolf, HH | 1 |
| Korytova, LI; Masliukova, EA; Meshechkin, AV; Sokurenko, VP; Zhabina, RM | 1 |
| Chang, CW; Shrestha, JP | 1 |
| Jia, Y; Li, X; Wang, X; Wen, Q; Xu, F; Xu, W; Zhang, L; Zhang, Y | 1 |
| Beebe, K; Huang, Y; Miyajima, N; Mollapour, M; Neckers, L; Nonomura, K; Rivas, C; Shinohara, N; Sourbier, C; Tatokoro, M; Trepel, JB; Tsutsumi, S; Yoshida, S | 1 |
| Beketić-Orešković, L; Kasum, M; Orešković, S; Šimunić, V | 1 |
| Abdel-Aziz, M; Abuo-Rahma, Gel-D; Ali, TF; Beshr, EA | 1 |
| Balalaie, S; Boloori, P; Sadjadi, M; Sheikhnejad, R; Tahoori, F | 1 |
| Bradner, JE; Chiang, CM; Conaway, J; Conaway, R; Fowler, T; Ghatak, P; Price, DH; Roy, AL; Shilatifard, A | 1 |
| Grandane, A; Supuran, CT; Tanc, M; Zalubovskis, R | 2 |
| Bates, RC; Proia, DA | 1 |
| Dalbøge, CS; Gøtzsche, PC; Johansen, HK; Jørgensen, KJ | 1 |
| Pertino, MW; Schmeda-Hirschmann, G; Theoduloz, C; Verdugo, V | 1 |
| Hou, J; Huang, W; Jiao, L; Li, Y; Liu, B; Qian, H; Qiu, Q; Zhao, T | 1 |
| Morris, AM | 1 |
| Beert, E; Bradner, J; Brems, H; Cichowski, K; Clapp, W; De Raedt, T; Helin, K; Hornick, JL; Kehrer-Sawatzki, H; Legius, E; Luscan, A; Mautner, V; Ortonne, N; Pasmant, E; Upadhyaya, M; Vidaud, M | 1 |
| Gilchrist, A; Karash, A; Mazzoni, MR | 1 |
| Blanchard-Desce, M; Cattoën, X; Chaix, A; Croissant, J; Durand, JO; Gallud, A; Garcia, M; Gary-Bobo, M; Hugues, V; Maynadier, M; Mongin, O; Raehm, L; Wong Chi Man, M | 1 |
| Alberto Marco, J; Carda, M; Díaz-Oltra, S; Falomir, E; Murga, J; Torijano-Gutiérrez, S; Vilanova, C | 1 |
| Abdou, WM; Ganoub, NA; Sabry, E | 1 |
| Fu, J; Katritzky, AR; Khaybullin, RN; Li, T; Liang, X; Okunieff, P; Qi, X; Zhang, M | 1 |
| Qi, J | 1 |
| Akkenapally, S; Kapavarapu, R; Kumar, CG; Murthy, NY; Pal, S; Praveena, KS; Shivaji Ramarao, EV | 1 |
| Liu, HM; Ma, LY; Pang, LP; Shao, KP; Wang, B; Wang, SQ; Xue, DQ; Zhang, M; Zheng, YC | 1 |
| Cabanillas Stanchi, KM; Döring, M; Ebinger, M; Eikemeier, M; Handgretinger, R; Hartmann, U; Müller, I; Schulz, A; Schwarze, CP | 1 |
| Jee, BC; Kim, JH; Kim, SH; Kim, SK; Lee, HJ; Lee, JR; Suh, CS | 1 |
| Bae-Jump, VL; Chan, LL; Gehrig, PA; Jackson, AL; Kilgore, JE; Qiu, H; Zhong, Y; Zhou, C | 1 |
| Cakmak, H; Rosen, MP | 1 |
| Butassi, E; Pertino, MW; Schmeda-Hirschmann, G; Theoduloz, C; Zacchino, S | 1 |
| Chinthakindi, PK; Hamid, A; Hussain, A; Khan, I; Koul, S; Majeed, R; Sangwan, PL; Saxena, AK; Sharma, PR | 1 |
| Goloubeva, O; McLenithan, J; Sabnis, G; Schech, A; Yu, S | 1 |
| Amore, B; Beaupre, DM; Caudillo, I; Deng, H; Fu, S; Hong, DS; Hwang, YC; Janku, F; Khan, R; Kurzrock, R; Lee, P; Loberg, R; Lockhart, AC; Ngarmchamnanrith, G; Rosen, P | 1 |
| Acquaviva, J; Astsaturov, I; Bates, RC; Chimmanamada, D; He, S; Inoue, T; Jimenez, JP; Khazak, V; Ogawa, LS; Osman, S; Proia, DA; Sang, J; Sequeira, M; Smith, DL; Tatsuta, N; Ying, W; Zhang, C; Zhang, J | 1 |
| Khuri, FR; Sun, SY; Yao, W; Yue, P | 1 |
| Chen, Y; Ding, J; Geng, M; Huang, M; Shen, A; Shen, YY; Sun, J; Wang, L; Wang, X; Yang, X | 1 |
| Chinnaiyan, AM; Engelke, CG | 1 |
| Baryawno, N; Calero, R; Darabi, A; Dyberg, C; Einvik, C; Johnsen, JI; Kogner, P; Kool, M; Milosevic, J; Sandén, E; Siesjö, P; Sveinbjörnsson, B; Wickström, M | 1 |
| Ferri, E; McKenna, CE; Petosa, C | 1 |
| Bubalo, JS; Lewis, JS; Pham, AN | 1 |
| Babu, KS; Chityal, GK; Hussaini, SM; Kamal, A; Shaik, TB; Yedla, P | 1 |
| Gong, P; Luo, R; Tang, Q; Tu, Q; Tu, Y; Wang, L; Wang, P; Wu, C; Zheng, P; Zhu, W | 1 |
| Abdul Razak, AR; Bartha-Vári, JH; Boros, Z; Cai, S; Carlson, R; Chong, YS; Chua, SY; Dagis, A; Feng, X; Foo, VH; Gabrail, NY; Gerecitano, JF; Gluckman, P; Huber, S; Ikram, MK; Irimie, FD; Kauffman, M; Kim, R; Kwek, K; Landesman, Y; Lassen, U; Li, D; Li, Q; Liu, C; Ma, J; Mahipal, A; Mau-Soerensen, M; McCauley, D; Mirza, MR; Nademanee, A; Ngo, C; Paizs, C; Palmer, JM; Pizzari, T; Poppe, L; Rashal, T; Saint-Martin, JR; Saw, SM; Shacham, S; Shields, AF; Stayner, LA; Tan, CS; Thorborg, K; Toşa, MI; Tsai, NC; Unger, TJ; Verkicharla, PK; Vértessy, BG; Wang, S; Wang, Y; Weiser, D; Wollin, M; Wong, TY; Xu, L; Yuan, L; Yuan, S; Zhang, Y; Zheng, R | 1 |
| Chattopadhyay, A; Galloway, WR; Galvagnion, C; Itzhaki, LS; O'Connor, CJ; Rahman, T; Spring, DR; Stokes, JE; Tan, YS; Verma, C; Zhang, F | 1 |
| Chen, GR; Field, RA; He, XP; Li, J; Zang, Y; Zeng, YL | 1 |
| Mahipal, A; Malafa, M | 1 |
| Scott, AR | 1 |
| Bózsity, N; Jerkovics, N; Mernyák, E; Minorics, R; Schneider, G; Szabó, J; Wölfling, J; Zupkó, I | 1 |
| Campaner, S; Croci, O; Donato, E; Morelli, MJ; Muller, H; Pelizzola, M; Sabò, A | 1 |
| Lal, K; Yadav, P | 1 |
| Allegrezza, MJ; Bengsch, F; Bitler, BG; Bradner, JE; Conejo-Garcia, JR; Kossenkov, AV; Rutkowski, MR; Svoronos, N; Yokoyama, Y; Zhang, R; Zhu, H | 1 |
| Domingo, J; Garcia-Velasco, JA | 1 |
| Kanaho, Y; Miura, Y; Yamauchi, Y | 1 |
| Dai, XJ; Liu, CJ; Liu, YP; Tao, JC; Yu, SL; Zhang, T | 1 |
| Diao, PC; Li, Q; Li, YH; Yang, HK; You, WW; Zhang, B; Zhao, PL | 1 |
| Azmi, AS; Mohammad, RM | 1 |
| Cetina, M; Grbčić, P; Gregorić, T; Kraljević Pavelić, S; Raić-Malić, S; Sedić, M; Tomljenović Paravić, A; Vianello, R | 1 |
| Bullinger, L; Döhner, H; Fröhling, S; Grasedieck, S; Kuchenbauer, F; Miller, C; Reinhart, S; Rouhi, A; Scholl, C; Stolze, B | 1 |
| Burd, CE; Crochiere, M; Elloul, S; Elnaggar, O; Farren, MR; Hennessey, RC; Kashyap, T; Kendra, K; Klebanov, B; Landesman, Y; Lesinski, GB; Shakya, R; Young, G | 1 |
| Ackerley, DF; Ashoorzadeh, A; Copp, JN; Flanagan, JU; Guise, CP; Mowday, AM; Patterson, AV; Sharrock, AV; Smaill, JB; Williams, EM | 1 |
| Sharp, PA; Suzuki, HI; Young, RA | 1 |
| Garner, D; Machin, K | 1 |
| Arya, N; Chu, QS; Cianfrocca, ME; Fleming, RA; Gale, M; Goldstein, LJ; Koch, KM; Loftiss, J; Murray, N; Pandite, L; Paul, E; Rowinsky, EK | 1 |
| Vestergaard, P | 1 |
| De Meester, I; Lambeir, AM; Scharpé, S | 1 |
| Barnett, J; Cuthbertson, A; Morrison, MS; Ricketts, SA; Tessier, J; Wedge, SR | 1 |
| Arribas López, JR | 1 |
| Oktay, K; Rodriguez-Wallberg, K; Schover, L | 1 |
| Azad, N; Figg, WD; Gardner, E; Graves, C; Imamura, CK; Kohn, EC; Kotz, H; Minasian, L; Perroy, A; Raggio, M; Sarosy, GA | 1 |
| Götz, C; Gratz, A; Jose, J | 1 |
| El-Mardenly, G; Ezzat, Y; Gheita, TA; Hammam, W; Sayed, S | 1 |
| Ayral-Kaloustian, S; Beyer, C; Zhang, N | 1 |
| Adams, J; Atwell, S; Aubol, BE; Blaney, JM; Bounaud, PY; Buchanan, SG; Burley, SK; Do, TH; Emtage, S; Felce, JD; Froning, KJ; Gessert, SF; Hendle, J; Holme, K; Huser, NH; Jessen, KA; Lee, PS; Leon, BC; Pelletier, LA; Peterman, MC; Reich, SH; Rooney, IA; Russell, M; Sauder, JM; Schwinn, KD; Smith, CR; Smyth, L; Sprengeler, PA; Tang, CM; Thompson, DA; Wasserman, SR | 1 |
| Chandrasekar, PH; Cronin, S | 1 |
| Aherne, W; Day, JE; Moody, CJ; Rowlands, MG; Sharp, SY; Workman, P | 1 |
| Miharu, M; Osumi, T; Shima, H; Shimada, H; Takahashi, T | 1 |
| Chan, RJ; Dong, Y; Gunawan, AM; He, Y; Jiang, ZX; Liu, S; Nabinger, SC; Wang, L; Wu, L; Yang, Z; Yu, Z; Zhang, X; Zhang, ZY | 1 |
| Nagar, S; Saha, A | 1 |
| Aerts, HJ; Brans, B; De Ruysscher, D; Dingemans, AM; Dubois, L; Hochstenbag, M; Janssen, MH; Kolb, H; Lalisang, R; Lambin, P; Ollers, M; van Dongen, GA; van Loon, J; Windhorst, B; Zhang, J | 1 |
| Peng, L; Qu, F; Xia, Y | 1 |
| Odio, CM | 1 |
| Jeong, HJ; Joung, MH; Kim, DW; Kim, EM; Lee, CM; Lim, ST; Sohn, MH | 1 |
| Bernhardt, PV; Dong, L; Gallen, MJ; Gordon, VA; Grange, RL; Johns, JP; Parsons, PG; Reddell, PW; Schill, H; Williams, CM | 1 |
| Ball, C; Bejot, R; Carroll, L; Elizarov, AM; Gouverneur, V; Hill, S; Kelly, C; Kersemans, V; King, RC; Kolb, HC; Miraghaie, R; Smart, S; Zhang, J | 1 |
| Arnold, SM; Bukowski, RM; Cooper, W; Gauthier, E; Lockhart, AC; Rothenberg, ML; Wang, KK; Wang-Gillam, A | 1 |
| Kim, BH; Kim, HM; Park, SK; Park, SM; Yang, H | 1 |
| Bonetti, M; Cole, BF; Gelber, RD; Lazar, AA | 1 |
| Dranitsaris, G; Khoury, H | 1 |
| Giaccone, G; Neckers, LM; Trepel, JB; Wang, Y | 1 |
| Barthel, A; Csuk, R; Schwarz, S; Sczepek, R; Siewert, B | 1 |
| Davis, JL; Goldstein, SC; Lombardi, LR; Miano, TA; Mitra, N; Morgan, SC; Vardhanabhuti, S; Vozniak, JM | 1 |
| Bai, L; Bellail, A; Hao, C; Liao, J; Liu, M; Lu, J; McEachern, D; Miller, R; Peng, Y; Qiu, S; Sun, H; Sun, SY; Ting, AT; Wang, S; Yi, H | 1 |
| Fandzloch, M; Szłyk, E; Wojtczak, A; Łakomska, I | 1 |
| Camp, D; Campitelli, M; Hegde, V; Quinn, RJ | 1 |
| Fang, Q; Feng, C; Gu, G; Hou, J; Li, Z; Liu, P; Shen, J; Shi, Y; Wang, H; Wang, P; Xu, F; Yin, Z | 1 |
| Årstad, E; El-Emir, E; Jathoul, AP; Pedley, RB; Rajkumar, V; Robson, M; Yan, R | 1 |
| Guo, L; Ju, R; Li, J; Wu, D; Ye, C; Zhang, D | 1 |
| Mitrokhin, SD; Sokolov, AA | 1 |
| Anderes, K; Chevrel, MC; Drygin, D; Haddach, M; Macalino, D; Nédellec, AS; O'Brien, SE; Pierre, F; Regan, CF; Ryckman, DM; Siddiqui-Jain, A; Stefan, E; Streiner, N | 1 |
| Moyer, MW | 1 |
| Barsoum, J; Bear, MD; Foley, KP; Inoue, T; London, CA; McCleese, J; Paalangara, R; Ying, W | 1 |
| Acquaviva, J; Barsoum, J; Blackman, RK; Du, Z; Foley, KP; Inoue, T; Koya, K; Ogawa, LS; Proia, DA; Sang, J; Sun, L; Tatsuta, N; Wada, Y; Ye, S; Ying, W; Zhou, D | 1 |
| Fujii, Y; Goitsuka, R; Igarashi, Y; Nakazawa, K; Ohtake, H; Ono, N; Takayama, T; Ueda, Y | 1 |
| Blyth, CC; Cole, C; Gottardo, NG; Hansford, JR | 1 |
| Hara, A; Kawai, G; Kimura, M; Matsuhashi, A; Nagano, A; Ohno, T; Okano, Y; Saio, M; Saitou, M; Shimizu, K; Takigami, I; Yamada, K | 1 |
| Aebi, C; Ammann, RA; Bernhard, S; Diepold, M; Kernland Lang, K; Leibundgut, K; Lüer, S | 1 |
| Burris, HA; Gordon, M; Infante, JR; Liu, R; Ramanathan, RK; Rooney, I; Rosen, L; Rugg, T; Zeh, K | 1 |
| Husain, A; Kumar, D; Mishra, R; Parveen, S; Rashid, M; Shin, DS | 1 |
| Dadmal, TL; Janaki Ramaiah, M; Kosurkar, UB; Kumbhare, RM; Pal-Bhadra, M; Pushpavalli, SN | 1 |
| Maxmen, A | 1 |
| Benci, K; Klobučar, M; Kraljević Pavelić, S; Mandić, L; Mintas, M; Pavelić, K; Sedić, M; Suhina, T; Wittine, K | 1 |
| Ashizaki, M; Czaplewska, JA; Funabiki, T; Gottschaldt, M; Kinoshita, I; Mikata, Y; Morimoto, K; Nakai, M; Nishioka, T; Obata, M; Ogura, S; Ohi, H; Okura, I; Schubert, US; Sugai, Y; Tanaka, R; Yano, S | 1 |
| Choi, HK; Lee, K | 1 |
| Angiolini, M; Asa, D; Avanzi, N; Badari, A; Bertrand, J; Casale, E; Cauteruccio, S; Cirla, A; Cozzi, L; D'Alessio, R; Donati, D; Galvani, A; Isacchi, A; Jackson, PK; Liu, Y; Magnaghi, P; Magnuson, S; Malgesini, B; Nuvoloni, S; O'Brien, T; Orrenius, C; Polucci, P; Riceputi, L; Rizzi, S; Sirtori, FR; Trucchi, B | 1 |
| Aibe, N; Kagiya, T; Kobayashi, K; Kodani, N; Koizumi, M; Nakamura, S; Tsubokura, T; Yamada, K; Yamazaki, H; Yoshida, K | 1 |
| Doong, H; Kassis, J; Kohn, EC; Patton, AM | 1 |
| Armstrong, D; Cross, EW; Perlin, DS; Safdar, A | 1 |
| DAINKO, JL; FEINSTEIN, RN | 1 |
| KOHLER, L; NIEPER, HA | 1 |
| NIEPER, HA; XALABARDER, C | 1 |
| NAPALKOV, NP | 1 |
| BISAGNI, E; ENNUYER, A; ROYER, R; ZAJDELA, F | 1 |
| HOZUMI, M; SUGIMURA, T | 1 |
| Baden, LR; DelVecchio, A; Doran, M; Fishman, JA; Katz, JT; Koziol, C; Rubin, RH | 1 |
| Goss, PE; Strasser-Weippl, K | 1 |
| Rubin, ZA; Somani, J | 1 |
| Cordonnier, C | 1 |
| DeMario, M; Desai, AA; Fleming, GF; Innocenti, F; Janisch, L; Ramirez, J; Ratain, MJ; Shepard, D | 1 |
| Christopoulos, S; Rivera, JA; Small, D; Trifiro, M | 1 |
| Bonatti, H; Dierich, MP; Freund, MC; Gastl, G; Gschwendtner, A; Gunsilius, E; Kropshofer, G; Lass-Flörl, C; Petzer, A | 1 |
| Klastersky, J | 1 |
| Jiang, J; Kamendulis, LM; Kaster, J; Klaunig, JE; Lafferty, JS | 1 |
| Banerjee, S; Chakraborty, S; Das, T; Kagiya, VT; Mukherjee, A; Nair, CK; Samuel, G; Sarma, HD; Venkatesh, M | 1 |
| Perfect, JR | 1 |
| Balwierz, W | 1 |
| Almajan, GL; Barbuceanu, S; Innocenti, A; Manole, G; Puccetti, L; Saramet, I; Scozzafava, A; Supuran, CT | 1 |
| Albert, ND; Kontoyiannis, DP; Lewis, RE; Lionakis, MS; Raad, II; Torres, HA | 1 |
| Baraldi, PG; Borea, PA; Fruttarolo, F; Gessi, S; Merighi, S; Romagnoli, R; Tabrizi, MA; Varani, K | 1 |
| Burke-Gaffney, A; Callister, ME; Nakamura, H | 1 |
| Bagg, J; Brailsford, S; Davies, AN; Jackson, MS; Sweeney, MP | 1 |
| Oktay, KH | 1 |
| Gøtzsche, PC; Johansen, HK; Jørgensen, KJ | 1 |
| Caldas Lopes, E; Chiosis, G; Solit, D | 1 |
| Balvay, D; Bessoud, B; Bois, FY; Brochot, C; Cuénod, CA; Siauve, N | 1 |
| Kontoyiannis, DP; Lewis, RE; Mulanovich, V; Raad, II | 1 |
| Singer, M | 1 |
| Ballard, P; Barlaam, BC; Bradbury, RH; Dishington, A; Hennequin, LF; Hickinson, DM; Hollingsworth, IM; Kettle, JG; Klinowska, T; Ogilvie, DJ; Pearson, SE; Scott, JS; Suleman, A; Whittaker, R; Williams, EJ; Wood, R; Wright, L | 1 |
| Jarque, I; Sanz, MA | 1 |
| Devaiah, V; Juvekar, A; Kamal, A; Kurian, N; Laxma Reddy, K; Sen, S; Shankaraiah, N; Zingde, S | 1 |
| Almyroudis, NG; Gonzalez, AV; Segal, BH; Ullmann, AJ | 1 |
| Anaissie, E; Buvé, K; Maertens, J | 1 |
| Ohyashiki, K | 1 |
| Herbrecht, R; Ribaud, P; Schlamm, HT; Wingard, JR | 1 |
| Friedlander, ML; Kohn, EC; Qu, XJ; Yang, JL; Yu, Y | 1 |
| Hilgard, P; Peukert, M; Pohl, J | 1 |
| Ehninger, G; Mölle, M; Schuler, U | 1 |
| Anaissie, EJ; Uzun, O | 1 |
| Anaissie, EJ; Andersson, BS; Bodey, GP; Champlin, RE; Giralt, SA; Kantarjian, HM; Karl, C; Kontoyiannis, DP; O'Brien, S; Vartivarian, S | 1 |
| Lee, JW; Walsh, TJ | 1 |
| Christian, M; Cole, K; Davis, PA; Figg, WD; Goldspiel, B; Jacob, J; Kohn, EC; Link, CJ; Liotta, LA; Reed, E; Sarosy, G | 1 |
| Alessandro, R; Kohn, EC; Spoonster, J; Wersto, RP | 1 |
| Kuwano, M; Ono, M | 1 |
| Alberti, D; Arzoomanian, RZ; Berlin, J; Cleary, J; Feierabend, C; Hutson, P; Rago, RP; Tutsch, KD; Wilding, G | 1 |
| Bauer, KS; Davis, PA; Figg, WD; Kohn, EC; Liotta, LA; Reed, E; Sarosy, GA; Soltis, MJ; Thompkins, A | 1 |
| Boudoulas, S; Cole, KA; Davis, PA; Figg, WD; Goldspiel, B; Jacob, J; Piscitelli, SC; Reed, E; Soltis, MJ; Steinberg, SM | 1 |
| Shibamoto, Y | 1 |
| Bauer, KS; Davis, P; Figg, WD; Kohler, D; Kohn, EC; Lush, RM; Reed, E; Steinberg, SM | 1 |
| Berthou, C; Bourge, JF; Denizot, Y; Geromin, D; Sasportes, M; Sigaux, F; Soulié, A; Zhang, Y | 1 |
| Chiou, CC; Groll, AH; Walsh, TJ | 1 |
| Krcmery, V | 1 |
| Kothari, L; Murugesan, S; Nair, CK; Noronha, OP; Samuel, AM; Shetty, SJ; Srivastava, TS | 1 |
| Bauer, KS; Bostick-Bruton, F; Figg, WD; Fuse, E; Goldspiel, B; Kohn, EC; Kulpa, V; Liotta, LA; Minasian, L; Noone, M; Pluda, J; Reed, E; Sarosy, GA; Tompkins, A | 1 |
| Libutti, SK; Zogakis, TG | 1 |
| Alberti, D; Arzoomanian, RZ; Berlin, J; Binger, K; Dresen, A; Feierabend, C; Marnocha, R; Pluda, J; Tutsch, KD; Wilding, G | 1 |
| Anaissie, E; Arndt, C; Donowitz, G; Finberg, R; Fioritoni, G; Garber, G; Greenberg, R; Hadley, S; Laverdière, M; Lazarus, HM; Lee, J; Pappas, P; Perfect, J; Petersen, F; Raffalli, J; Reboli, A; Reinhardt, J; Schuster, M; Stiff, P; Walsh, TJ; Wingard, J; Winston, DJ; Yanovich, S | 1 |
| Blumer, JL; Lazarus, HM; Romero, A; Schlamm, H; Yanovich, S | 1 |
| Habel, F; Hoban, D; Laverdiere, M; Restieri, C | 1 |
| Forbes, PD; Urbach, F | 1 |
| Fiebig, HH; Heim, ME; Peukert, M; Possinger, K; Queisser, W; Wander, HE | 1 |
| Crespeigne, N; Decoster, G; Dodion, P; Gerard, B; Kenis, Y; Lambert, M; Nicaise, C; Rozencweig, M | 1 |
| Cunningham, D; Forrest, GJ; Gilchrist, NL; Kaye, SB; Setanoians, A; Soukop, M; Stuart, JF | 1 |
| Bach, F; Cavalli, F; Hansen, HH; Hansen, SW; Kaplan, S | 1 |
| Brockman, RW | 1 |
| Kroes, R; Verschuuren, HG | 1 |
| Tudhope, GR | 1 |
| Steele, MW; Vaughan, MH | 1 |
65 review(s) available for triazoles and Benign Neoplasms
| Article | Year |
|---|---|
1,2,3-Triazole hybrids as anticancer agents: A review.
Topics: Animals; Antineoplastic Agents; Drug Development; Drug Discovery; Humans; Neoplasms; Structure-Activity Relationship; Triazoles | 2022 |
Design and Development of Triazole Derivatives as Prospective Anticancer Agents: A Review.
Topics: Acridines; Antineoplastic Agents; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms; Prospective Studies; Pyrimidines; Structure-Activity Relationship; Triazoles | 2022 |
Therapeutic potential of 1,2,3-triazole hybrids for leukemia treatment.
Topics: Antineoplastic Agents; Humans; Leukemia; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles | 2022 |
Synthetic and Medicinal Perspective of 1,2,4-Triazole as Anticancer Agents.
Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles | 2022 |
Triazole-fused pyrimidines in target-based anticancer drug discovery.
Topics: Antineoplastic Agents; Humans; Neoplasms; Pyrimidines; Structure-Activity Relationship; Triazoles | 2023 |
Recent updates on 1,2,3-triazole-containing hybrids with in vivo therapeutic potential against cancers: A mini-review.
Topics: Antineoplastic Agents; Cell Proliferation; Humans; Neoplasms; Structure-Activity Relationship; Triazoles | 2023 |
Role of Ganetespib, an HSP90 Inhibitor, in Cancer Therapy: From Molecular Mechanisms to Clinical Practice.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; HSP90 Heat-Shock Proteins; Humans; Neoplasms; Phosphatidylinositol 3-Kinases; Triazoles | 2023 |
Steroid-triazole conjugates: A brief overview of synthesis and their application as anticancer agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms; Steroids; Structure-Activity Relationship; Triazoles | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide | 2023 |
1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships.
Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles | 2019 |
The Advances of the Structure and Function of Indoleamine 2, 3- dioxygenase 1 and Its Inhibitors.
Topics: Alzheimer Disease; Antineoplastic Agents; Depression; Drug Design; Enzyme Inhibitors; Gene Expression; Histocompatibility, Maternal-Fetal; Humans; Imidazoles; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Indoles; Neoplasms; Neuroprotective Agents; Signal Transduction; Structure-Activity Relationship; Triazoles; Tumor Escape | 2020 |
Developments in the Application of 1,2,3-Triazoles in Cancer Treatment.
Topics: Antineoplastic Agents; Drug Development; Drug Discovery; Humans; Neoplasms; Patents as Topic; Structure-Activity Relationship; Triazoles | 2020 |
Pyrazoline Hybrids as Promising Anticancer Agents: An Up-to-Date Overview.
Topics: Antineoplastic Agents; Cell Proliferation; Coumarins; Humans; Molecular Structure; Neoplasms; Nitrogen; Pyrazoles; Steroids; Structure-Activity Relationship; Triazoles | 2020 |
Peptide-Drug Conjugates with Different Linkers for Cancer Therapy.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Cell Line, Tumor; Humans; Neoplasms; Oximes; Peptides; Pharmaceutical Preparations; Triazoles; Xenograft Model Antitumor Assays | 2021 |
Thiazolidinone-linked1,2,3-triazoles with monoterpenic skeleton as new potential anticancer agents: Design, synthesis and molecular docking studies.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Neoplasms; Thiazolidinediones; Triazoles | 2021 |
Hyperbranched Polymers with Controllable Topologies for Drug Delivery.
Topics: Drug Carriers; Humans; Hydrophobic and Hydrophilic Interactions; Micelles; Neoplasms; Pharmaceutical Preparations; Polyethylene Glycols; Polymers; Triazoles | 2018 |
JQ1: a novel potential therapeutic target.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azepines; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Proliferation; Cell Survival; Estrogen Receptor alpha; Humans; Molecular Targeted Therapy; Neoplasms; Nuclear Proteins; Signal Transduction; Transcription Factors; Triazoles | 2018 |
Bromodomain Drug Discovery - the Past, the Present, and the Future.
Topics: Antineoplastic Agents; Azepines; Cell Cycle Proteins; Drug Discovery; Drug Synergism; Humans; Neoplasms; Nuclear Proteins; Proteins; Transcription Factors; Triazoles; Ubiquitin-Protein Ligases | 2018 |
1,2,4-Triazolo[1,5-a]pyrimidines in drug design.
Topics: Animals; Chemistry, Pharmaceutical; Drug Design; Humans; Neoplasms; Parasitic Diseases; Pyrimidines; Structure-Activity Relationship; Triazoles | 2019 |
Exploring the Chemistry and Therapeutic Potential of Triazoles: A Comprehensive Literature Review.
Topics: Humans; Infections; Inflammation; Neoplasms; Neurodegenerative Diseases; Oxidative Stress; Seizures; Triazoles | 2019 |
Iron chelation in the treatment of cancer: a new role for deferasirox?
Topics: Animals; Antineoplastic Agents; Benzoates; Deferasirox; Deferiprone; Deferoxamine; Humans; Iron Chelating Agents; Neoplasms; Pyridones; Triazoles | 2013 |
Ganetespib and HSP90: translating preclinical hypotheses into clinical promise.
Topics: Animals; Antineoplastic Agents; Drug Evaluation, Preclinical; HSP90 Heat-Shock Proteins; Humans; Neoplasms; Triazoles | 2014 |
Voriconazole versus amphotericin B or fluconazole in cancer patients with neutropenia.
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Fluconazole; Humans; Liposomes; Mycoses; Neoplasms; Neutropenia; Opportunistic Infections; Pyrimidines; Randomized Controlled Trials as Topic; Triazoles; Voriconazole | 2014 |
Pharmacological intervention at CCR1 and CCR5 as an approach for cancer: help or hindrance.
Topics: Animals; Antineoplastic Agents; Cyclohexanes; HIV Infections; Humans; Maraviroc; Molecular Structure; Neoplasms; Receptors, CCR1; Receptors, CCR5; Triazoles | 2014 |
Bromodomain and extraterminal domain inhibitors (BETi) for cancer therapy: chemical modulation of chromatin structure.
Topics: Azepines; Cell Cycle Proteins; Chromatin Assembly and Disassembly; Epigenesis, Genetic; Humans; Models, Molecular; Neoplasms; Nuclear Proteins; RNA Processing, Post-Transcriptional; Transcription Factors; Triazoles | 2014 |
Random-start ovarian stimulation in patients with cancer.
Topics: Adult; Aromatase Inhibitors; Chorionic Gonadotropin; Cryopreservation; Female; Fertility Preservation; Fertilization in Vitro; Follicle Stimulating Hormone; Humans; Infertility, Female; Letrozole; Luteal Phase; Neoplasms; Nitriles; Oocyte Retrieval; Oocytes; Ovulation Induction; Treatment Outcome; Triazoles | 2015 |
aBETting therapeutic resistance by Wnt signaling.
Topics: Animals; Azepines; Biomarkers, Tumor; Drug Resistance; Mice; Models, Animal; Neoplasms; Triazoles; Wnt Proteins; Wnt Signaling Pathway | 2015 |
Bromodomains: Structure, function and pharmacology of inhibition.
Topics: Acetylation; Antineoplastic Agents; Autoimmune Diseases; Azepines; Benzodiazepines; Cardiotonic Agents; Cardiovascular Diseases; Chromatin; Chromatin Assembly and Disassembly; Drug Discovery; Epigenesis, Genetic; Histones; Humans; Models, Molecular; Neoplasms; Transcription Factors; Transcription, Genetic; Triazoles | 2016 |
Carbohydrate CuAAC click chemistry for therapy and diagnosis.
Topics: Alkynes; Anti-Infective Agents; Antineoplastic Agents; Azides; Carbohydrates; Catalysis; Chemistry, Pharmaceutical; Click Chemistry; Cycloaddition Reaction; Glycosylation; Humans; Imino Sugars; Neoplasms; Signal Transduction; Triazoles | 2016 |
Importins and exportins as therapeutic targets in cancer.
Topics: Active Transport, Cell Nucleus; Animals; Cell Nucleus; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Exportin 1 Protein; Humans; Hydrazines; Karyopherins; Neoplasms; ran GTP-Binding Protein; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Triazoles | 2016 |
Recent Advancements in 1,4-Disubstituted 1H-1,2,3-Triazoles as Potential Anticancer Agents.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Humans; Neoplasms; Triazoles | 2018 |
Oocyte cryopreservation for fertility preservation in women with cancer.
Topics: Cryopreservation; Estradiol; Female; Fertility Preservation; Humans; Infertility, Female; Letrozole; Neoplasms; Nitriles; Oocyte Retrieval; Oocytes; Ovulation Induction; Pregnancy; Pregnancy Rate; Reproductive Techniques, Assisted; Triazoles | 2016 |
Machineries regulating the activity of the small GTPase Arf6 in cancer cells are potential targets for developing innovative anti-cancer drugs.
Topics: Adaptor Proteins, Signal Transducing; ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Animals; Antineoplastic Agents; Cell Cycle Proteins; Chlorobenzenes; Disease Progression; Gene Expression Regulation, Neoplastic; Guanine Nucleotide Exchange Factors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Neoplasms; Nerve Tissue Proteins; Purines; Pyrazoles; Pyrimidinones; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Triazoles | 2017 |
Super-Enhancer-Mediated RNA Processing Revealed by Integrative MicroRNA Network Analysis.
Topics: Animals; Azepines; Enhancer Elements, Genetic; Gene Expression Regulation; Histone Code; Humans; Mice; MicroRNAs; Neoplasms; Organ Specificity; RNA Processing, Post-Transcriptional; Transcription Factors; Transcription, Genetic; Triazoles | 2017 |
Skeletal effects of drugs to treat cancer.
Topics: Anastrozole; Animals; Antineoplastic Agents; Aromatase Inhibitors; Bone Density; Bone Diseases, Metabolic; Fractures, Bone; Humans; Neoplasms; Nitriles; Triazoles | 2008 |
DPP4 inhibitors for diabetes--what next?
Topics: Adamantane; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Hypoxia; Neoplasms; Nitriles; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Triazoles; Vildagliptin | 2008 |
[Secondary effects of treatment with maraviroc and other CCR5 antagonists. Potential impact of the CCR5 blocker].
Topics: Adult; Benzoates; CCR5 Receptor Antagonists; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Comorbidity; Cyclohexanes; Diketopiperazines; Disease Susceptibility; Drug Design; env Gene Products, Human Immunodeficiency Virus; HIV Fusion Inhibitors; HIV Infections; Homozygote; Humans; Hyperlipidemias; Incidence; Infections; Maraviroc; Membrane Fusion; Neoplasms; Piperazines; Receptors, CCR5; Sequence Deletion; Spiro Compounds; Triazoles; Virus Attachment; Virus Internalization | 2008 |
Cevipabulin (TTI-237): preclinical and clinical results for a novel antimicrotubule agent.
Topics: Animals; Antimitotic Agents; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Drug Evaluation, Preclinical; Humans; Hydrocarbons, Halogenated; Mice; Microtubules; Neoplasms; Rats; Triazoles | 2009 |
Safety of triazole antifungal drugs in patients with cancer.
Topics: Antifungal Agents; Antineoplastic Agents; Drug Interactions; Drug Monitoring; Humans; Mycoses; Neoplasms; Triazoles | 2010 |
Triazole nucleoside derivatives bearing aryl functionalities on the nucleobases show antiviral and anticancer activity.
Topics: Antineoplastic Agents; Antiviral Agents; Drug Design; Hepatitis C; Humans; Neoplasms; Nucleosides; Triazoles | 2010 |
[Antifungal therapy for infants, children and adolescents with suspected or documented invasive fungal infection].
Topics: Adolescent; Antifungal Agents; Antineoplastic Agents; Candidiasis; Child; Child, Preschool; Fever; Humans; Infant; Infant, Newborn; Mycoses; Neoplasms; Neutropenia; Triazoles | 2010 |
STA-9090, a small-molecule Hsp90 inhibitor for the potential treatment of cancer.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Drug Approval; Drug Evaluation, Preclinical; HSP90 Heat-Shock Proteins; Humans; Mice; Neoplasms; Structure-Activity Relationship; Triazoles | 2010 |
Recent updates on the development of ganetespib as a Hsp90 inhibitor.
Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Clinical Trials as Topic; Drug Design; HSP90 Heat-Shock Proteins; Humans; Neoplasms; Protein Folding; Triazoles | 2012 |
Calcium as a molecular target in angiogenesis.
Topics: Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Membrane; Humans; Neoplasms; Neovascularization, Pathologic; Neovascularization, Physiologic; Triazoles | 2003 |
New options for the treatment of invasive fungal infections.
Topics: Adult; Antifungal Agents; Aspergillosis; Candidiasis; Caspofungin; Echinocandins; Female; Fungemia; Humans; Immunocompromised Host; Lipopeptides; Male; Middle Aged; Mycetoma; Mycoses; Neoplasms; Opportunistic Infections; Peptides; Peptides, Cyclic; Pyrimidines; Scedosporium; Triazoles; Voriconazole | 2004 |
Fungal infections: current diagnosis and treatment.
Topics: Amphotericin B; Antifungal Agents; Fungemia; Humans; Immunocompromised Host; Mycoses; Neoplasms; Neutropenia; Premedication; Randomized Controlled Trials as Topic; Risk Factors; Triazoles | 2004 |
Hormonal manipulation of benign metastasizing leiomyomas: report of two cases and review of the literature.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Brachial Plexus Neuropathies; Enzyme Inhibitors; Estrogen Receptor Modulators; Female; Gonadotropin-Releasing Hormone; Humans; Leiomyoma; Lung Neoplasms; Magnetic Resonance Imaging; Middle Aged; Neoplasm Invasiveness; Neoplasms; Nitriles; Radiography, Thoracic; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Triazoles; Uterine Neoplasms | 2004 |
Management of invasive mycoses in hematology patients: current approaches.
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Candidiasis; Deoxycholic Acid; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Resistance, Fungal; Echinocandins; Fungal Proteins; Hematopoietic Stem Cell Transplantation; Humans; Liposomes; Mycoses; Neoplasms; Neutropenia; Peptides, Cyclic; Randomized Controlled Trials as Topic; Survival Analysis; Triazoles | 2004 |
Pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine ligands, new tools to characterize A3 adenosine receptors in human tumor cell lines.
Topics: Adenosine A3 Receptor Antagonists; Animals; Humans; Ligands; Neoplasms; Pyrimidines; Receptor, Adenosine A3; Triazoles | 2005 |
Thioredoxin: friend or foe in human disease?
Topics: Cardiovascular Diseases; Dioxanes; Humans; Molecular Structure; Naphthalenes; Neoplasms; Pyridazines; Spiro Compounds; Thioredoxins; Triazoles | 2005 |
Voriconazole versus amphotericin B in cancer patients with neutropenia.
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Fluconazole; Humans; Liposomes; Mycoses; Neoplasms; Neutropenia; Opportunistic Infections; Pyrimidines; Randomized Controlled Trials as Topic; Triazoles; Voriconazole | 2006 |
Heat shock protein-90 inhibitors: a chronicle from geldanamycin to today's agents.
Topics: Adenosine Triphosphate; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Benzoquinones; Binding, Competitive; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Molecular Structure; Neoplasms; Protein Conformation; Protein-Tyrosine Kinases; Pyrimidines; Quinones; Triazoles | 2006 |
[Current indications for voriconazole in onco-hematological patients].
Topics: Amphotericin B; Antibiotic Prophylaxis; Antifungal Agents; Drug Resistance, Fungal; Hematologic Diseases; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Multicenter Studies as Topic; Mycoses; Neoplasms; Neutropenia; Opportunistic Infections; Pyrimidines; Randomized Controlled Trials as Topic; Salvage Therapy; Spain; Triazoles; Voriconazole; Zygomycosis | 2007 |
Broad-spectrum antifungal prophylaxis in patients with cancer at high risk for invasive mold infections: point.
Topics: Antifungal Agents; Fluconazole; Humans; Immunocompromised Host; Itraconazole; Mycoses; Myelodysplastic Syndromes; Neoplasms; Neutropenia; Risk Assessment; Triazoles | 2008 |
Broad-spectrum antifungal prophylaxis in patients with cancer at high risk for invasive mold infections: counterpoint.
Topics: Antifungal Agents; Antigens, Fungal; Aspergillosis; beta-Glucans; Enzyme-Linked Immunosorbent Assay; Humans; Immunocompromised Host; Mycoses; Neoplasms; Neutropenia; Proteoglycans; Risk Assessment; Tomography, X-Ray Computed; Triazoles | 2008 |
[Development trend in new therapeutic approaches for anemia].
Topics: Anemia; Benzoates; Clinical Trials as Topic; Darbepoetin alfa; Deferasirox; Erythropoietin; Hematinics; Humans; Iron Chelating Agents; Iron Overload; Lenalidomide; Myelodysplastic Syndromes; Neoplasms; Thalidomide; Triazoles | 2008 |
[Prophylaxis and therapy of fungal infections in oncology].
Topics: Amphotericin B; Antifungal Agents; Fluconazole; Humans; Incidence; Mycoses; Neoplasms; Triazoles | 1995 |
Antifungal prophylaxis in patients with hematologic malignancies: a reappraisal.
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Bone Marrow Transplantation; Candidiasis; Clinical Trials as Topic; Disease Susceptibility; Drug Administration Routes; Hematopoietic Cell Growth Factors; Humans; Immunocompromised Host; Leukocyte Transfusion; Mycoses; Neoplasms; Neutropenia; Triazoles | 1995 |
Prevention of invasive fungal infections in patients with neoplastic disease.
Topics: Amphotericin B; Aspergillosis; Candidiasis; Cytokines; Drug Administration Routes; Humans; Imidazoles; Neoplasms; Opportunistic Infections; Polyenes; Triazoles | 1993 |
Signal transduction as a therapeutic target.
Topics: Animals; Antineoplastic Agents; Calcium; Calcium Channel Blockers; Clinical Trials as Topic; Growth Substances; GTP-Binding Proteins; Humans; Ion Channel Gating; Ion Channels; Mice; Neoplasm Proteins; Neoplasms; Oncogenes; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins p21(ras); Receptor Protein-Tyrosine Kinases; Signal Transduction; Triazoles | 1996 |
[Development of anti tumor agents targeting angiogenesis].
Topics: Antineoplastic Agents; Clinical Trials as Topic; Cyclohexanes; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Hydroxamic Acids; Interferon-alpha; Interleukin-12; Neoplasms; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Phenylalanine; Platelet Factor 4; Polysaccharides, Bacterial; Sesquiterpenes; Thalidomide; Thiophenes; Triazines; Triazoles; Tumor Cells, Cultured | 1997 |
[Contribution of radiation biology to the development of radiation therapy].
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Dose Fractionation, Radiation; Humans; Imidazoles; Lung Neoplasms; Neoplasms; Nimorazole; Radiation-Sensitizing Agents; Triazoles | 1999 |
New drugs and novel targets for treatment of invasive fungal infections in patients with cancer.
Topics: Anidulafungin; Antifungal Agents; Echinocandins; Humans; Immunocompromised Host; Lipopeptides; Lipoproteins; Micafungin; Mycoses; Neoplasms; Opportunistic Infections; Peptides, Cyclic; Pyrimidines; Triazoles; Voriconazole | 2000 |
General aspects of anti-angiogenesis and cancer therapy.
Topics: Angiogenesis Inhibitors; Animals; Antibodies; Clinical Trials as Topic; Collagen; Cyclohexanes; Endostatins; Endothelial Growth Factors; Fatty Acids, Unsaturated; Humans; Interleukin-12; Lymphokines; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Neoplasms; O-(Chloroacetylcarbamoyl)fumagillol; Peptide Fragments; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Receptors, Vitronectin; RNA, Catalytic; Sesquiterpenes; Suramin; Thalidomide; Triazoles; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Biochemical aspects of drug combinations.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Bleomycin; Camptothecin; Cell Division; Cytarabine; Deferoxamine; Diamines; DNA, Neoplasm; Doxorubicin; Drug Therapy, Combination; Leukemia L1210; Macromolecular Substances; Mice; Neoplasms; Neoplasms, Experimental; Nitrosourea Compounds; Purine Nucleotides; Ribonucleotide Reductases; Thioguanine; Triazoles | 1974 |
33 trial(s) available for triazoles and Benign Neoplasms
| Article | Year |
|---|---|
Supportive care for the prevention of nausea, vomiting and anorexia in a phase 1B study of selinexor in advanced cancer patients: an exploratory study.
Topics: Adult; Aged; Anorexia; Antiemetics; Female; Humans; Hydrazines; Male; Middle Aged; Nausea; Neoplasms; Olanzapine; Triazoles; Vomiting; Young Adult | 2022 |
Selinexor in combination with carboplatin and paclitaxel in patients with advanced solid tumors: Results of a single-center, multi-arm phase Ib study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Female; Humans; Hydrazines; Lung Neoplasms; Nausea; Neoplasms; Ovarian Neoplasms; Paclitaxel; Thrombocytopenia; Triazoles; Vomiting | 2022 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide | 2023 |
Selinexor in combination with topotecan in patients with advanced or metastatic solid tumors: Results of an open-label, single-center, multi-arm phase Ib study.
Topics: Active Transport, Cell Nucleus; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Exportin 1 Protein; Female; Humans; Hydrazines; Karyopherins; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Receptors, Cytoplasmic and Nuclear; Topotecan; Triazoles | 2021 |
A Phase 1 study evaluating AMG 337 in Asian patients with advanced solid tumors.
Topics: Adult; Aged; Asian People; Cohort Studies; Female; Humans; Male; Middle Aged; Neoplasms; Protein Kinase Inhibitors; Pyridones; Triazoles | 2017 |
Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors.
Topics: Administration, Oral; Adult; Animals; Biological Availability; Cell Line, Tumor; Diarrhea; Dogs; Dose-Response Relationship, Drug; Drug Eruptions; Drug Evaluation, Preclinical; Fatigue; Female; Humans; Indazoles; Male; MAP Kinase Signaling System; Maximum Tolerated Dose; Mice; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nausea; Neoplasm Staging; Neoplasms; Protein Kinase Inhibitors; Pyridines; Pyrrolidines; Rats; Triazoles; Xenograft Model Antitumor Assays; Young Adult | 2018 |
A Phase I Study of Ganetespib and Ziv-Aflibercept in Patients with Advanced Carcinomas and Sarcomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Neoplasms; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Sarcoma; Triazoles | 2018 |
A phase I study of the safety and tolerability of VLX600, an Iron Chelator, in patients with refractory advanced solid tumors.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Drug Resistance, Neoplasm; Female; Humans; Hydrazones; Iron Chelating Agents; Male; Middle Aged; Neoplasms; Triazoles | 2019 |
A non-randomized trial to assess the safety, tolerability, and pharmacokinetics of posaconazole oral suspension in immunocompromised children with neutropenia.
Topics: Administration, Oral; Adolescent; Age Factors; Antifungal Agents; Antineoplastic Agents; Area Under Curve; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Immunocompromised Host; Infant; Invasive Fungal Infections; Male; Neoplasms; Neutropenia; Prospective Studies; Triazoles | 2019 |
Pharmacokinetic characteristics of vactosertib, a new activin receptor-like kinase 5 inhibitor, in patients with advanced solid tumors in a first-in-human phase 1 study.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aniline Compounds; Area Under Curve; Drug Administration Schedule; Female; Half-Life; Humans; Male; Middle Aged; Neoplasms; Receptor, Transforming Growth Factor-beta Type I; Triazoles | 2020 |
A first in human, safety, pharmacokinetics, and clinical activity phase I study of once weekly administration of the Hsp90 inhibitor ganetespib (STA-9090) in patients with solid malignancies.
Topics: Adult; Aged; Aged, 80 and over; Drug Administration Schedule; Female; HSP90 Heat-Shock Proteins; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Neoplasms; Treatment Outcome; Triazoles | 2013 |
Iron chelation with deferasirox for the treatment of secondary hemosiderosis in pediatric oncology patients: a single-center experience.
Topics: Adolescent; Benzoates; Chelation Therapy; Child; Child, Preschool; Deferasirox; Female; Ferritins; Hemosiderosis; Humans; Infant; Iron; Iron Chelating Agents; Male; Neoplasms; Transfusion Reaction; Triazoles; Young Adult | 2013 |
A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Dose-Response Relationship, Drug; Fatigue; Female; Humans; Hypertension; Immunohistochemistry; In Situ Hybridization, Fluorescence; Male; Metabolic Clearance Rate; Middle Aged; Nausea; Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridazines; Remission Induction; Treatment Outcome; Triazoles | 2015 |
Topics: Active Transport, Cell Nucleus; Adolescent; Adult; Aged; Aged, 80 and over; Atrial Natriuretic Factor; Benzhydryl Compounds; Benzylamines; Biopsy; Blood Glucose; Blood Transfusion; Cholesterol, LDL; Combined Modality Therapy; Cyclams; Diabetes Mellitus, Type 2; Disease Progression; Drug Administration Schedule; Enzyme-Linked Immunosorbent Assay; Female; Glucosides; Glycated Hemoglobin; Granulocyte Colony-Stimulating Factor; Hamstring Muscles; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Heterocyclic Compounds; Hodgkin Disease; Humans; Hydrazines; Immunohistochemistry; Insulin-Secreting Cells; Leg; Male; Middle Aged; Muscle Strength; Neoplasms; Peripheral Blood Stem Cell Transplantation; Range of Motion, Articular; Recurrence; Remission Induction; Research Design; Reverse Transcriptase Polymerase Chain Reaction; Soccer; Sodium-Glucose Transport Proteins; Sodium-Glucose Transporter 2 Inhibitors; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; Triazoles; Young Adult | 2015 |
A phase I and pharmacokinetic study of lapatinib in combination with letrozole in patients with advanced cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Female; Humans; Lapatinib; Letrozole; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Nitriles; Ovarian Neoplasms; Quinazolines; Triazoles | 2008 |
A phase I study of paclitaxel and continuous daily CAI in patients with refractory solid tumors.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Paclitaxel; Treatment Outcome; Triazoles; Young Adult | 2009 |
PET imaging of hypoxia using [18F]HX4: a phase I trial.
Topics: Aged; Cell Hypoxia; Dose-Response Relationship, Drug; Female; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Neoplasms; Nitroimidazoles; Positron-Emission Tomography; Time Factors; Triazoles | 2010 |
A phase I dose escalation study of TTI-237 in patients with advanced malignant solid tumors.
Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Drug Administration Schedule; Early Termination of Clinical Trials; Female; Half-Life; Humans; Hydrocarbons, Halogenated; Infusions, Intravenous; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Treatment Outcome; Triazoles; Tubulin Modulators | 2012 |
[Modern antifungals in therapy of nosocomial mycosis in oncologic patients].
Topics: Antifungal Agents; Candida; Candidiasis, Invasive; Cross Infection; Drug Resistance, Fungal; Female; Fluconazole; Humans; Male; Neoplasms; Pyrimidines; Triazoles; Voriconazole | 2011 |
Unexpected renal toxicity associated with SGX523, a small molecule inhibitor of MET.
Topics: Adolescent; Animals; Dogs; Follow-Up Studies; Haplorhini; Humans; Male; Neoplasms; Prognosis; Proto-Oncogene Proteins c-met; Pyridazines; Rats; Renal Insufficiency; Triazoles | 2013 |
Feasibility trial for daily oral administration of the hypoxic sensitizer AK-2123 (Sanazole) in radiotherapy.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Feasibility Studies; Female; Humans; Male; Middle Aged; Neoplasms; Radiation-Sensitizing Agents; Triazoles | 2013 |
A phase I trial of pharmacokinetic modulation of carboxyamidotriazole (CAI) with ketoconazole in patients with advanced cancer.
Topics: Adult; Aged; Antifungal Agents; Antineoplastic Agents; Capsules; Chemistry, Pharmaceutical; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Female; Humans; Ketoconazole; Male; Middle Aged; Neoplasms; Triazoles | 2004 |
Changes in causes of death over time after treatment for invasive aspergillosis.
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Cause of Death; Graft vs Host Disease; Humans; Neoplasms; Pyrimidines; Survival Rate; Time Factors; Triazoles; Voriconazole | 2008 |
Effectiveness of an oral triazole for opportunistic mold infections in patients with cancer: experience with SCH 39304.
Topics: Administration, Oral; Adult; Aged; Antifungal Agents; Female; Humans; Leukemia; Male; Middle Aged; Mycoses; Neoplasms; Opportunistic Infections; Prospective Studies; Triazoles | 1993 |
Clinical investigation of a cytostatic calcium influx inhibitor in patients with refractory cancers.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Calcium Channel Blockers; Female; Humans; Male; Middle Aged; Neoplasms; Triazoles | 1996 |
Phase I clinical and pharmacokinetic study of oral carboxyamidotriazole, a signal transduction inhibitor.
Topics: Antineoplastic Agents; Capsules; Digestive System; Drug Administration Schedule; Female; Gels; Hematopoiesis; Humans; Male; Middle Aged; Neoplasms; Nervous System; Signal Transduction; Triazoles | 1997 |
Phase I trial of micronized formulation carboxyamidotriazole in patients with refractory solid tumors: pharmacokinetics, clinical outcome, and comparison of formulations.
Topics: Adult; Aged; Antineoplastic Agents; Drug Administration Schedule; Drug Compounding; Female; Humans; Male; Middle Aged; Neoplasms; Triazoles | 1997 |
Pharmacokinetics of orally administered carboxyamido-triazole, an inhibitor of calcium-mediated signal transduction.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Calcium; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Neoplasms; Signal Transduction; Triazoles | 1995 |
Pharmacokinetics and relative bioavailability of carboxyamido-triazole with respect to food and time of administration: use of a single model for simultaneous determination of changing parameters.
Topics: Adult; Antineoplastic Agents; Area Under Curve; Biological Availability; Cohort Studies; Cross-Over Studies; Female; Food-Drug Interactions; Humans; Male; Middle Aged; Neoplasms; Triazoles | 1998 |
A phase I trial of carboxyamido-triazole and paclitaxel for relapsed solid tumors: potential efficacy of the combination and demonstration of pharmacokinetic interaction.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Inhibitory Concentration 50; Male; Mice; Mice, Nude; Middle Aged; Neoplasms; Neovascularization, Pathologic; Ovarian Neoplasms; Paclitaxel; Recurrence; Time Factors; Treatment Outcome; Triazoles; Tumor Cells, Cultured | 2001 |
Phase I and pharmacokinetic study of a micronized formulation of carboxyamidotriazole, a calcium signal transduction inhibitor: toxicity, bioavailability and the effect of food.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biological Availability; Calcium; Calcium Channel Blockers; Capsules; Diet Therapy; Drug Administration Schedule; Female; Gels; Hematopoiesis; Humans; Intestinal Absorption; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Nervous System; Triazoles | 2002 |
Voriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent fever.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Chemical and Drug Induced Liver Injury; Child; Chronic Disease; Female; Fever; Humans; Infusions, Intravenous; Male; Middle Aged; Mycoses; Neoplasms; Neutropenia; Prospective Studies; Pyrimidines; Triazoles; Voriconazole | 2002 |
Safety and pharmacokinetics of oral voriconazole in patients at risk of fungal infection: a dose escalation study.
Topics: Administration, Oral; Adult; Antifungal Agents; Dose-Response Relationship, Drug; Double-Blind Method; Female; Graft Rejection; Hematologic Neoplasms; Humans; Male; Middle Aged; Mycoses; Neoplasms; Pyrimidines; Risk Factors; Triazoles; Voriconazole | 2002 |
216 other study(ies) available for triazoles and Benign Neoplasms
| Article | Year |
|---|---|
A Redox-Responsive Nanovaccine Combined with A2A Receptor Antagonist for Cancer Immunotherapy.
Topics: Adenosine A2 Receptor Antagonists; Cancer Vaccines; CD8-Positive T-Lymphocytes; Humans; Immunotherapy; Killer Cells, Natural; Nanomedicine; Neoplasms; Oxidation-Reduction; Pyrimidines; Triazoles; Tumor Microenvironment | 2021 |
New Bioactive Fused Triazolothiadiazoles as Bcl-2-Targeted Anticancer Agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Design; HeLa Cells; Humans; Inhibitory Concentration 50; Jurkat Cells; Models, Chemical; Molecular Structure; Molecular Targeted Therapy; Neoplasms; Proto-Oncogene Proteins c-bcl-2; Structure-Activity Relationship; Thiadiazoles; Triazoles | 2021 |
Second near-infrared photothermal-amplified immunotherapy using photoactivatable composite nanostimulators.
Topics: Animals; Azepines; B7-H1 Antigen; Cell Line, Tumor; Copper; Dendritic Cells; Humans; Immunogenic Cell Death; Immunotherapy; Indocyanine Green; Infrared Rays; Liposomes; Mice; Mice, Inbred C57BL; Nanoparticles; Neoplasms; Phototherapy; Toll-Like Receptor 9; Transplantation, Heterologous; Triazoles | 2021 |
Exploring the Synergistic Anticancer Potential of Benzofuran-Oxadiazoles and Triazoles: Improved Ultrasound- and Microwave-Assisted Synthesis, Molecular Docking, Hemolytic, Thrombolytic and Anticancer Evaluation of Furan-Based Molecules.
Topics: A549 Cells; Antineoplastic Agents; Benzofurans; Cell Survival; Chemistry Techniques, Synthetic; Hemolysis; Humans; Microwaves; Molecular Docking Simulation; Neoplasms; Oxadiazoles; Triazoles | 2022 |
QSAR and Molecular Docking Studies of Pyrimidine-Coumarin-Triazole Conjugates as Prospective Anti-Breast Cancer Agents.
Topics: Antineoplastic Agents; Coumarins; Humans; Molecular Docking Simulation; Neoplasms; Pyrimidines; Quantitative Structure-Activity Relationship; Triazoles | 2022 |
Real-World Comparison of Isavuconazole and Voriconazole in Terms of the Need for Dosage Adjustments Guided by Clinical Pharmacological Advice During Primary Prophylaxis of Invasive Fungal Infections in Pediatric Patients with Hemato-Oncological Malignanci
Topics: Antifungal Agents; Azoles; Child; Humans; Invasive Fungal Infections; Neoplasms; Nitriles; Pyridines; Retrospective Studies; Triazoles; Voriconazole | 2022 |
Ganetespib selectively sensitizes cancer cells for proximal and distal spread-out Bragg peak proton irradiation.
Topics: Dose-Response Relationship, Radiation; Humans; Neoplasms; Protons; Relative Biological Effectiveness; Triazoles | 2022 |
Selinexor synergizes with azacitidine to eliminate myelodysplastic syndrome cells through p53 nuclear accumulation.
Topics: Azacitidine; Humans; Hydrazines; Myelodysplastic Syndromes; Neoplasms; Triazoles; Tumor Suppressor Protein p53 | 2022 |
Structural aspects of triazole derivatives as HSP90 inhibitors for the treatment of cancer:
Topics: Amino Acids; Antineoplastic Agents; HSP90 Heat-Shock Proteins; Molecular Docking Simulation; Neoplasms; Quantitative Structure-Activity Relationship; Triazoles | 2023 |
Synthesis and Biological Activity Evaluation of Pyrazole-1,2,4-triazole Hybrids: A Computer-aided Docking Studies.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Pyrazoles; Staphylococcus aureus; Structure-Activity Relationship; Triazoles | 2023 |
Exploration of 1,2,3-triazole linked benzenesulfonamide derivatives as isoform selective inhibitors of human carbonic anhydrase.
Topics: Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Humans; Isoenzymes; Molecular Docking Simulation; Molecular Structure; Neoplasms; Structure-Activity Relationship; Sulfonamides; Triazoles | 2023 |
Design and Synthesis of Acridine-Triazole and Acridine-Thiadiazole Derivatives and Their Inhibitory Effect against Cancer Cells.
Topics: Acridines; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dermatologic Agents; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Thiadiazoles; Triazoles; Zebrafish | 2022 |
Health economic analysis of patients treated with isavuconazole in a German comprehensive cancer centre.
Topics: Antifungal Agents; Aspergillosis; Humans; Invasive Fungal Infections; Neoplasms; Nitriles; Triazoles | 2023 |
Targeting HER2-receptors with
Topics: Animals; Cell Line, Tumor; Mice; Mice, SCID; Neoplasms; Peptides; Peptides, Cyclic; Peptidomimetics; Tissue Distribution; Triazoles | 2023 |
Novel Compounds with Promising IDO1 Inhibitory Activity As New Cancer Drug Candidates: Derivatives Of N, N'-diphenylurea Linked With 1,2,3-triazole.
Topics: Antineoplastic Agents; Enzyme Inhibitors; Indoleamine-Pyrrole 2,3,-Dioxygenase; Neoplasms; Structure-Activity Relationship; Triazoles | 2023 |
Keto-bridged dual triazole-linked benzenesulfonamides as potent carbonic anhydrase and cathepsin B inhibitors.
Topics: Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cathepsin B; Humans; Molecular Docking Simulation; Neoplasms; Protein Isoforms; Structure-Activity Relationship; Triazoles | 2023 |
Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group.
Topics: Animals; Cell Line, Tumor; Click Chemistry; Cytokines; Enzyme Inhibitors; Humans; Mice; Neoplasms; Nicotinamide Phosphoribosyltransferase; Triazoles | 2019 |
New amide linked dimeric 1,2,3-triazoles bearing aryloxy scaffolds as a potent antiproliferative agents and EGFR tyrosine kinase phosphorylation inhibitors.
Topics: Amides; Antineoplastic Agents; Cell Proliferation; Click Chemistry; Drug Design; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Structure-Activity Relationship; Triazoles | 2019 |
Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Carcinogenesis; Cell Line, Tumor; Energy Metabolism; Enzyme Inhibitors; HeLa Cells; Homeostasis; Humans; MCF-7 Cells; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Neoplasms; para-Aminobenzoates; Protein Serine-Threonine Kinases; Signal Transduction; Sulfones; Tankyrases; Triazoles; Xenograft Model Antitumor Assays | 2019 |
New Platinum(II) Triazole Thiosemicarbazone Complexes: Analysis of Their Reactivity and Potential Antitumoral Action.
Topics: Antineoplastic Agents; Coordination Complexes; Hep G2 Cells; Humans; MCF-7 Cells; Neoplasms; Platinum; Thiosemicarbazones; Triazoles | 2020 |
One-Pot Radiosynthesis and Biological Evaluation of a Caspase-3 Selective 5-[
Topics: Animals; Apoptosis; Caspase 3; Cell Line, Tumor; Copper; Fluorine Radioisotopes; Heterografts; Humans; Iodine Radioisotopes; Isatin; Mice; Neoplasms; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Triazoles | 2019 |
The Discovery of 7-Methyl-2-[(7-methyl[1,2,4]triazolo[1,5-
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Class Ib Phosphatidylinositol 3-Kinase; DNA-Activated Protein Kinase; Dogs; Drug Discovery; Humans; Mice; Molecular Structure; Neoplasms; Protein Kinase Inhibitors; Purines; Pyrans; Rats; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Structure-Activity Relationship; Triazoles; Xenograft Model Antitumor Assays | 2020 |
Discovery and Characterization of 1
Topics: Animals; Calcium; Cell Line, Tumor; Colonic Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Drug Discovery; Female; HEK293 Cells; Humans; Immunotherapy; Macrophages; Mice; Mice, Inbred BALB C; Microsomes, Liver; Neoplasms; RAW 264.7 Cells; Receptors, Prostaglandin E, EP4 Subtype; Structure-Activity Relationship; T-Lymphocytes, Cytotoxic; Triazoles; Tumor Microenvironment | 2020 |
General mechanism of JQ1 in inhibiting various types of cancer.
Topics: Azepines; Cell Cycle Proteins; Cell Line, Tumor; Drug Delivery Systems; Humans; Neoplasm Proteins; Neoplasms; Transcription Factors; Triazoles | 2020 |
Synthesis and Antiproliferative Evaluation of Novel Longifolene-Derived Tetralone Derivatives Bearing 1,2,4-Triazole Moiety.
Topics: Cell Proliferation; Hep G2 Cells; Humans; Magnetic Resonance Spectroscopy; MCF-7 Cells; Neoplasms; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Tetralones; Triazoles | 2020 |
Genetic and pharmacological targeting of A2a receptor improves function of anti-mesothelin CAR T cells.
Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; HEK293 Cells; HeLa Cells; Humans; Immunotherapy, Adoptive; Mesothelin; Neoplasms; Pyrimidines; Receptor, Adenosine A2A; Receptors, Chimeric Antigen; Signal Transduction; Triazoles; Tumor Microenvironment; Up-Regulation | 2020 |
Tumor localization of oncolytic adenovirus assisted by pH-degradable microgels with JQ1-mediated boosting replication and PD-L1 suppression for enhanced cancer therapy.
Topics: A549 Cells; Adenoviridae; Animals; Azepines; B7-H1 Antigen; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Mice, Nude; Microgels; Neoplasms; Oncolytic Virotherapy; Proteins; Triazoles | 2020 |
Design of Radiolabeled Analogs of Minigastrin by Multiple Amide-to-Triazole Substitutions.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Gastrins; Humans; Lutetium; Mice; Neoplasms; Peptidomimetics; Protein Binding; Radioisotopes; Radiopharmaceuticals; Receptor, Cholecystokinin B; Triazoles | 2020 |
Synthesis and In Vitro Cytotoxicity and Antibacterial Activity of Novel 1,2,3-Triazol-5-yl-phosphonates.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bacteria; Humans; Neoplasms; Organophosphonates; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured | 2020 |
Initial posaconazole dosing to achieve therapeutic serum posaconazole concentrations among children, adolescents, and young adults receiving delayed-release tablet and intravenous posaconazole.
Topics: Administration, Oral; Adolescent; Antifungal Agents; Body Weight; Child; Child, Preschool; Delayed-Action Preparations; Female; Hematologic Diseases; Humans; Immunocompromised Host; Infusions, Intravenous; Invasive Fungal Infections; Male; Neoplasms; Retrospective Studies; Tablets; Treatment Outcome; Triazoles; Young Adult | 2020 |
Galectin-3 Stimulates Tyro3 Receptor Tyrosine Kinase and Erk Signalling, Cell Survival and Migration in Human Cancer Cells.
Topics: Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Blood Proteins; Cell Line, Tumor; Cell Movement; Cell Survival; Galectin 3; Galectins; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Neoplasms; Phosphorylation; Protein S; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Staurosporine; Triazoles | 2020 |
A novel series of substituted 1,2,3-triazoles as cancer stem cell inhibitors: Synthesis and biological evaluation.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Fibroblasts; Humans; Leukocytes, Mononuclear; Mice; Neoplasms; Neoplastic Stem Cells; Triazoles | 2021 |
Synthesis and evaluation of in vitro cytotoxic effects of triazol/spiroindolinequinazolinedione, triazol/indolin-3-thiosemicarbazone and triazol/thiazol-indolin-2-one conjugates.
Topics: Antineoplastic Agents; bcl-2-Associated X Protein; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Molecular Structure; Neoplasms; Oxindoles; PC-3 Cells; Proto-Oncogene Proteins c-bcl-2; Structure-Activity Relationship; Thiosemicarbazones; Triazoles | 2020 |
Antiproliferative effect of mitochondria-targeting allobetulin 1,2,3-triazolium salt derivatives and their mechanism of inducing apoptosis of cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Membrane Potential, Mitochondrial; Mitochondria; Neoplasms; Reactive Oxygen Species; Triazoles | 2020 |
Topics: Animals; Antineoplastic Agents, Alkylating; Drug Resistance, Neoplasm; Escherichia coli Proteins; Etanidazole; Genes, Reporter; Genetic Therapy; Genetic Vectors; HCT116 Cells; Humans; Hydrocarbons, Fluorinated; Imidazoles; Indicators and Reagents; Mice; Molecular Imaging; Neoplasms; Nitrogen Mustard Compounds; Nitroreductases; Positron-Emission Tomography; Precision Medicine; Proof of Concept Study; Radiopharmaceuticals; Recombinant Proteins; Triazoles; Tumor Hypoxia; Xenograft Model Antitumor Assays | 2020 |
Experience using intravenous posaconazole in paediatric and young adult oncology patients.
Topics: Administration, Oral; Adolescent; Adult; Antifungal Agents; Child; Child, Preschool; Humans; Infant; Neoplasms; Retrospective Studies; Triazoles; Young Adult | 2020 |
ATF2 inhibits ani-tumor effects of BET inhibitor in a negative feedback manner by attenuating ferroptosis.
Topics: A549 Cells; Activating Transcription Factor 2; Animals; Antineoplastic Agents; Azepines; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Feedback, Physiological; Female; Ferroptosis; HeLa Cells; Heterocyclic Compounds, 4 or More Rings; Humans; MAP Kinase Signaling System; Mice; Mice, Nude; Neoplasms; NF-E2-Related Factor 2; Proteins; RNA, Messenger; Triazoles; Xenograft Model Antitumor Assays | 2021 |
Development of triazolothiadiazine derivatives as highly potent tubulin polymerization inhibitors: Structure-activity relationship, in vitro and in vivo study.
Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Binding Sites; Cell Proliferation; Female; G2 Phase Cell Cycle Checkpoints; HEK293 Cells; Humans; Mice, Inbred BALB C; Molecular Structure; Neoplasms; Protein Binding; Structure-Activity Relationship; Thiadiazines; Triazoles; Tubulin; Tubulin Modulators; Xenograft Model Antitumor Assays | 2020 |
Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azepines; B7-H1 Antigen; Cell Line, Tumor; Female; Immune Checkpoint Inhibitors; Irinotecan; Mice; Mice, Inbred BALB C; Neoplasms; Programmed Cell Death 1 Receptor; T-Lymphocytes, Regulatory; Triazoles; Tumor Microenvironment | 2021 |
Fluorescent palladium(II) and platinum(II) NHC/1,2,3-triazole complexes: antiproliferative activity and selectivity against cancer cells.
Topics: Antineoplastic Agents; Cell Line; Cell Proliferation; Cell Survival; Coordination Complexes; Coumarins; Fluorescence; Humans; Microscopy, Fluorescence; Neoplasms; Organometallic Compounds; Palladium; Platinum; Triazoles | 2021 |
Inhibition of DNA-PK with AZD7648 Sensitizes Tumor Cells to Radiotherapy and Induces Type I IFN-Dependent Durable Tumor Control.
Topics: Animals; Cell Line, Tumor; DNA-Activated Protein Kinase; Interferon Type I; Mice; Neoplasms; Protein Kinase Inhibitors; Purines; Pyrans; Radiation-Sensitizing Agents; Triazoles | 2021 |
Triazole based isatin derivatives as potential inhibitor of key cancer promoting kinases- insight from electronic structure, docking and molecular dynamics simulations.
Topics: Electronics; Humans; Isatin; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Neoplasms; Protein Binding; Protein Kinase Inhibitors; Triazoles | 2021 |
Combining selective inhibitors of nuclear export (SINEs) with chimeric antigen receptor (CAR) T cells for CD19‑positive malignancies.
Topics: Active Transport, Cell Nucleus; Antigens, CD19; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coculture Techniques; Combined Modality Therapy; Cytoplasm; Exportin 1 Protein; Humans; Hydrazines; Immunotherapy, Adoptive; Karyopherins; Neoplasms; Receptors, Chimeric Antigen; Receptors, Cytoplasmic and Nuclear; STAT3 Transcription Factor; Time Factors; Triazoles | 2021 |
Synthesis and Antiproliferative Evaluation of 2-Deoxy-
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; HeLa Cells; Humans; Imidazoles; Neoplasms; Temperature; Triazoles | 2021 |
Discovery of a potent MLL1 and WDR5 protein-protein interaction inhibitor with in vivo antitumor activity.
Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Histone-Lysine N-Methyltransferase; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Mice; Mice, Nude; Molecular Docking Simulation; Myeloid-Lymphoid Leukemia Protein; Neoplasms; Protein Binding; Protein Interaction Maps; Structure-Activity Relationship; Transplantation, Heterologous; Triazoles | 2021 |
Impact of antifungal stewardship interventions on the susceptibility of colonized Candida species in pediatric patients with malignancy.
Topics: Adolescent; Amphotericin B; Antifungal Agents; Antimicrobial Stewardship; Candida; Caspofungin; Child; Child, Preschool; Colony Count, Microbial; Disease Susceptibility; Drug Resistance, Fungal; Female; Fluconazole; Humans; Male; Microbial Sensitivity Tests; Neoplasms; Triazoles | 2021 |
Integrated pan-cancer of AURKA expression and drug sensitivity analysis reveals increased expression of AURKA is responsible for drug resistance.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Azepines; Benzodioxoles; Biomarkers, Tumor; Camptothecin; Cell Line, Tumor; Chromones; Dactinomycin; Datasets as Topic; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Irinotecan; Kaplan-Meier Estimate; Male; Middle Aged; Morpholines; Neoplasms; Prognosis; Pyridines; Triazoles | 2021 |
New 3-(1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one-based triazole derivatives: Design, synthesis, and biological evaluation as antiproliferative and apoptosis-inducing agents.
Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Design; Female; Humans; Inhibitory Concentration 50; Neoplasms; Quinolines; Reactive Oxygen Species; Structure-Activity Relationship; Triazoles | 2021 |
Synthesis and anti-cancer activities of new sulfonamides 4-substituted-triazolyl nucleosides.
Topics: Aminoimidazole Carboxamide; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cycloaddition Reaction; Humans; Neoplasms; Nucleosides; Ribonucleotides; Sulfonamides; Triazoles | 2017 |
Triazole-linked fluorescent bisboronic acid capable of selective recognition of the Lewis Y antigen.
Topics: Anthracenes; Antigens, Tumor-Associated, Carbohydrate; Boronic Acids; Cell Line, Tumor; Fluorescent Dyes; Humans; Lewis Blood Group Antigens; Microscopy, Fluorescence; Neoplasms; Oligosaccharides; Sialyl Lewis X Antigen; Triazoles | 2017 |
Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity.
Topics: Antineoplastic Agents; Apoptosis; Cell Movement; Cell Proliferation; Enzyme Inhibitors; Glucuronidase; Humans; Neoplasms; Thiadiazoles; Triazoles; Tumor Cells, Cultured | 2017 |
Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors.
Topics: Antineoplastic Agents; Azepines; Benzodiazepines; Citric Acid Cycle; CRISPR-Cas Systems; Dehydroepiandrosterone; Fumarates; Gene Knockout Techniques; Glucosephosphate Dehydrogenase; Glycolysis; HCT116 Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Metabolomics; Mitochondria; Mutation; Neoplasms; Oxygen Consumption; Phenformin; Phosphoglycerate Dehydrogenase; Proto-Oncogene Proteins c-myc; RNA Interference; RNA, Small Interfering; Succinate Dehydrogenase; Succinic Acid; Triazoles | 2017 |
Design, Synthesis, and Biological Evaluation of Coumarin-Triazole Hybrid Molecules as Potential Antitumor and Pancreatic Lipase Agents.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Coumarins; Drug Design; Enzyme Inhibitors; Hot Temperature; Humans; Lipase; Microwaves; Neoplasms; Structure-Activity Relationship; Swine; Triazoles | 2017 |
Targeting energy metabolism of cancer cells: Combined administration of NCL-240 and 2-DG.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Survival; Chlorophenols; Deoxyglucose; Drug Interactions; Energy Metabolism; Humans; Liposomes; Neoplasms; Triazoles | 2017 |
Ovarian Stimulation in Patients With Cancer: Impact of Letrozole and BRCA Mutations on Fertility Preservation Cycle Outcomes.
Topics: Adult; Aromatase Inhibitors; BRCA1 Protein; Cryopreservation; Female; Fertility Preservation; Fertilization in Vitro; Follicle Stimulating Hormone; Humans; Letrozole; Mutation; Neoplasms; Nitriles; Oocytes; Ovulation Induction; Triazoles; Young Adult | 2018 |
Retrospective Analysis of Posaconazole Suspension Dosing Strategies in a Pediatric Oncology Population: Single-Center Experience.
Topics: Adolescent; Antifungal Agents; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Male; Neoplasms; Retrospective Studies; Suspensions; Triazoles | 2017 |
Discovery of novel [1,2,4]triazolo[4,3-a]quinoxaline aminophenyl derivatives as BET inhibitors for cancer treatment.
Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Cycle Checkpoints; Cell Line, Tumor; Drug Evaluation, Preclinical; Half-Life; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Neoplasms; Nuclear Proteins; Protein Structure, Tertiary; Proto-Oncogene Proteins c-myc; Quinoxalines; Rats; Structure-Activity Relationship; Triazoles | 2017 |
Candida infanticola and Candida spencermartinsiae yeasts: Possible emerging species in cancer patients.
Topics: Adolescent; Antifungal Agents; Candida; Candidiasis; Caspofungin; Child, Preschool; Echinocandins; Fluconazole; Humans; Kluyveromyces; Lipopeptides; Male; Microbial Sensitivity Tests; Middle Aged; Neoplasms; Nitriles; Opportunistic Infections; Pichia; Pyridines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Triazoles; Voriconazole | 2018 |
Effects of posaconazole (a strong CYP3A4 inhibitor), two new tablet formulations, and food on the pharmacokinetics of idasanutlin, an MDM2 antagonist, in patients with advanced solid tumors.
Topics: Administration, Oral; Area Under Curve; Biological Availability; Cross-Over Studies; Cytochrome P-450 CYP3A Inhibitors; Drug Compounding; Drug Interactions; Fasting; Female; Food-Drug Interactions; Humans; Male; Middle Aged; Neoplasm Staging; Neoplasms; para-Aminobenzoates; Proto-Oncogene Proteins c-mdm2; Pyrrolidines; Tablets; Therapeutic Equivalency; Triazoles | 2018 |
Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death.
Topics: Apoptosis; Autophagy; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Humans; Neoplasms; Oxazoles; Phenylurea Compounds; Receptor, ErbB-2; Signal Transduction; Triazoles | 2018 |
[Usefulness of Suvorexant for Complicated Delirium in Cancer Patients Who Experience Sleep Disturbance during Hospitalization].
Topics: Azepines; Delirium; Follow-Up Studies; Hospitalization; Humans; Neoplasms; Retrospective Studies; Sleep Aids, Pharmaceutical; Triazoles | 2018 |
Isoform selectivity of harmine-conjugated 1,2,3-triazoles against human monoamine oxidase.
Topics: Antineoplastic Agents; Click Chemistry; Harmine; Humans; Kinetics; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neoplasms; Protein Isoforms; Structure-Activity Relationship; Triazoles | 2018 |
Purines and triazolo[4,3-e]purines containing pyrazole moiety as potential anticancer and antioxidant agents.
Topics: A549 Cells; Antineoplastic Agents; Antioxidants; Apoptosis; Caspases; Cell Line, Tumor; DNA Damage; Drug Screening Assays, Antitumor; Humans; Neoplasms; Purines; Structure-Activity Relationship; Triazoles | 2018 |
Correlation of structural features of novel 1,2,3-triazoles with their neurotoxic and tumoricidal properties.
Topics: Animals; Cell Line, Tumor; Cell Survival; Clone Cells; Dopaminergic Neurons; Humans; Neoplasms; Neurites; Neurotoxins; Triazoles | 2018 |
Novel benzotriazole N-acylarylhydrazone hybrids: Design, synthesis, anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis and FAK inhibition.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Focal Adhesion Protein-Tyrosine Kinases; Humans; Hydrazones; Molecular Docking Simulation; Neoplasms; Triazoles | 2018 |
Synthesis and evaluation of the cytotoxic activity of Furanaphthoquinones tethered to 1H-1,2,3-triazoles in Caco-2, Calu-3, MDA-MB231 cells.
Topics: Antineoplastic Agents; Caco-2 Cells; Cell Line, Tumor; Cell Survival; DNA Topoisomerases, Type I; Humans; Models, Molecular; Naphthoquinones; Neoplasms; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Triazoles | 2018 |
Loss of p53 expression in cancer cells alters cell cycle response after inhibition of exportin-1 but does not prevent cell death.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Lineage; Cell Survival; Exportin 1 Protein; G1 Phase; Humans; Hydrazines; Imidazoles; Karyopherins; Neoplasms; Piperazines; Proto-Oncogene Proteins c-mdm2; Receptors, Cytoplasmic and Nuclear; Triazoles; Tumor Suppressor Protein p53 | 2018 |
Synthesis, anticancer activity and molecular modeling studies of 1,2,4-triazole derivatives as EGFR inhibitors.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Molecular Docking Simulation; Neoplasms; Structure-Activity Relationship; Triazoles | 2018 |
Co-inhibition of BET and proteasome enhances ER stress and Bim-dependent apoptosis with augmented cancer therapeutic efficacy.
Topics: A549 Cells; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azepines; Bcl-2-Like Protein 11; Cell Line, Tumor; Cell Survival; Drug Synergism; Endoplasmic Reticulum Stress; HCT116 Cells; Humans; Mice, Nude; Neoplasms; Oligopeptides; Proteasome Inhibitors; Proteins; RNA Interference; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays | 2018 |
Design, synthesis and evaluation of novel hybrids between 4-anilinoquinazolines and substituted triazoles as potent cytotoxic agents.
Topics: Amino Acid Sequence; Aniline Compounds; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Molecular Docking Simulation; Neoplasms; Quinazolines; Sequence Alignment; Structure-Activity Relationship; Triazoles | 2018 |
Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Topics: Antineoplastic Agents; Azepines; Cell Cycle Proteins; Cell Proliferation; Gene Expression Regulation, Neoplastic; HEK293 Cells; HeLa Cells; Humans; K562 Cells; Models, Molecular; Molecular Targeted Therapy; Neoplasms; Nuclear Proteins; Protein Binding; Protein Conformation; Protein Interaction Domains and Motifs; Protein Interaction Maps; Protein Serine-Threonine Kinases; Proteomics; RNA-Binding Proteins; Signal Transduction; Structure-Activity Relationship; Transcription Factors; Triazoles | 2019 |
Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction.
Topics: Cell Line, Tumor; Cell Membrane; Drug Discovery; Humans; Neoplasms; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Binding; ras Proteins; Signal Transduction; Triazoles | 2019 |
Leucine ureido derivatives as aminopeptidase N inhibitors using click chemistry. Part II.
Topics: Antineoplastic Agents; CD13 Antigens; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Drug Design; Humans; Leucine; Neoplasms; Protease Inhibitors; Structure-Activity Relationship; Triazoles | 2019 |
A High-Throughput Glycosyltransferase Inhibition Assay for Identifying Molecules Targeting Fucosylation in Cancer Cell-Surface Modification.
Topics: Drug Screening Assays, Antitumor; Enzyme Inhibitors; Fucose; Fucosyltransferases; Glycosylation; High-Throughput Screening Assays; Humans; Neoplasms; Small Molecule Libraries; Triazoles | 2019 |
SOX9 is controlled by the BRD4 inhibitor JQ1 via multiple regulation mechanisms.
Topics: Azepines; Cell Cycle Proteins; Cell Line, Tumor; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; SOX9 Transcription Factor; Transcription Factors; Triazoles | 2019 |
Reprogramming Tumor Immune Microenvironment (TIME) and Metabolism via Biomimetic Targeting Codelivery of Shikonin/JQ1.
Topics: Azepines; Biomimetics; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Dendritic Cells; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Immunotherapy; Lactoferrin; Lectins, C-Type; Low Density Lipoprotein Receptor-Related Protein-1; Macrophages; Mannose; Mannose Receptor; Mannose-Binding Lectins; Nanoparticles; Naphthoquinones; Neoplasms; Receptors, Cell Surface; Triazoles; Tumor Microenvironment | 2019 |
JQ1, a BET-bromodomain inhibitor, inhibits human cancer growth and suppresses PD-L1 expression.
Topics: Azepines; B7-H1 Antigen; Carcinoma, Renal Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Gene Expression; Humans; Neoplasms; Primary Cell Culture; RNA, Messenger; Signal Transduction; Triazoles | 2019 |
Overview and outcome of mucormycosis among children with cancer: Report from the Children's Cancer Hospital Egypt.
Topics: Adolescent; Amphotericin B; Antifungal Agents; Cancer Care Facilities; Child; Child, Preschool; Egypt; Female; Hematologic Neoplasms; Hospitals, Pediatric; Humans; Immunocompromised Host; Male; Mucormycosis; Neoplasms; Opportunistic Infections; Retrospective Studies; Risk Factors; Treatment Outcome; Triazoles | 2019 |
Ferritinophagy is required for the induction of ferroptosis by the bromodomain protein BRD4 inhibitor (+)-JQ1 in cancer cells.
Topics: Amino Acid Transport System y+; Animals; Azepines; Cell Cycle Proteins; Cell Line, Tumor; Databases, Factual; Down-Regulation; Female; Ferroptosis; Fusion Regulatory Protein 1, Heavy Chain; Histone-Lysine N-Methyltransferase; Humans; Mice; Mice, Nude; Neoplasms; Phospholipid Hydroperoxide Glutathione Peroxidase; Sirtuin 1; Survival Rate; Transcription Factors; Triazoles | 2019 |
SF2523: Dual PI3K/BRD4 Inhibitor Blocks Tumor Immunosuppression and Promotes Adaptive Immune Responses in Cancer.
Topics: Adaptive Immunity; Animals; Azepines; Cell Line, Tumor; Cell Polarity; Disease Models, Animal; Female; Immune Tolerance; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Morpholines; Neoplasms; Nuclear Proteins; Phosphoinositide-3 Kinase Inhibitors; Pyrans; Transcription Factors; Triazoles; Tumor Burden; Tumor Microenvironment | 2019 |
l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan.
Topics: Antineoplastic Agents; Brain Diseases; Click Chemistry; Dose-Response Relationship, Drug; Histidine; Humans; Large Neutral Amino Acid-Transporter 1; Molecular Structure; Neoplasms; Prodrugs; Structure-Activity Relationship; Triazoles; Tryptophan | 2019 |
Discovery of aromatic amides with triazole-core as potent reversal agents against P-glycoprotein-mediated multidrug resistance.
Topics: Amides; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzamides; Click Chemistry; Cytochrome P-450 CYP3A; Doxorubicin; Drug Discovery; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; K562 Cells; Neoplasms; Triazoles | 2019 |
Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity.
Topics: Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Humans; Methylation; Molecular Docking Simulation; Neoplasms; Protein Binding; Protein-Arginine N-Methyltransferases; Pyrimidines; Pyrroles; Quinolines; Structure-Activity Relationship; Triazoles | 2019 |
Nucleoside dimers analogs containing floxuridine and thymidine with unnatural linker groups: synthesis and cancer line studies. Part III.
Topics: Antineoplastic Agents; Cell Survival; Click Chemistry; Cycloaddition Reaction; Dimerization; Floxuridine; HeLa Cells; Humans; KB Cells; MCF-7 Cells; Neoplasms; Nucleosides; Thymidine; Triazoles | 2019 |
Response to ovarian stimulation in patients facing gonadotoxic therapy.
Topics: Adult; Antineoplastic Agents; Female; Fertility Preservation; Fertilization in Vitro; Gonadotropins; Humans; Letrozole; Neoplasms; Nitriles; Oocyte Retrieval; Ovary; Ovulation Induction; Triazoles | 2013 |
Selective inhibition of tumor oncogenes by disruption of super-enhancers.
Topics: Antineoplastic Agents; Azepines; Cell Cycle Proteins; Cell Line, Tumor; Chromatin; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Humans; Mediator Complex; Multiple Myeloma; Neoplasms; Nuclear Proteins; Transcription Elongation, Genetic; Transcription Factors; Transcription, Genetic; Triazoles | 2013 |
Gene expression: Super enhancers.
Topics: Animals; Antineoplastic Agents; Azepines; Cell Lineage; Embryonic Stem Cells; Enhancer Elements, Genetic; Humans; Mediator Complex; Neoplasms; Nuclear Proteins; Transcription Factors; Transcription, Genetic; Triazoles | 2013 |
Synthesis, biological evaluation, and molecular docking studies of novel 1,3,4-oxadiazole derivatives possessing benzotriazole moiety as FAK inhibitors with anticancer activity.
Topics: Antineoplastic Agents; Focal Adhesion Protein-Tyrosine Kinases; HT29 Cells; Humans; MCF-7 Cells; Molecular Docking Simulation; Neoplasms; Oxadiazoles; Protein Kinase Inhibitors; Structure-Activity Relationship; Triazoles | 2013 |
Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA.
Topics: Acetylation; Amino Acid Sequence; Animals; Azepines; Cell Line, Tumor; HEK293 Cells; Humans; Mice; Molecular Sequence Data; Neoplasms; NF-kappa B; Nuclear Proteins; Protein Binding; Protein Structure, Tertiary; Transcription Factor RelA; Transcription Factors; Triazoles | 2014 |
Gadolinium-deferasirox-D-glucosamine: novel anti-tumor and MR molecular (theranostic) imaging agent.
Topics: Animals; Antineoplastic Agents; Benzoates; Cell Line, Tumor; Chromatography, Thin Layer; Contrast Media; Deferasirox; Disease Models, Animal; Gadolinium; Glucosamine; Glucose; Hexokinase; Humans; Magnetic Resonance Imaging; Mice, Nude; Microscopy, Fluorescence; Neoplasms; Phosphorylation; Radionuclide Imaging; Radiopharmaceuticals; Rats; Time Factors; Triazoles; Tumor Necrosis Factor-alpha | 2013 |
1,2,3-Triazoles as amide bond mimics: triazole scan yields protease-resistant peptidomimetics for tumor targeting.
Topics: Amides; Humans; Neoplasms; Peptidomimetics; Triazoles | 2013 |
2-Amino-[1,2,4]triazolo[1,5-a]pyridines as JAK2 inhibitors.
Topics: Amitrole; Animals; Antineoplastic Agents; Crystallography, X-Ray; Humans; Janus Kinase 2; Mice; Models, Molecular; Neoplasms; Pyrimidines; Structure-Activity Relationship; Triazoles | 2013 |
Regioselective synthesis of 6-aryl-benzo[h][1,2,4]-triazolo[5,1-b]quinazoline-7,8-diones as potent antitumoral agents.
Topics: Aldehydes; Antineoplastic Agents; Catalysis; Cell Line, Tumor; Hep G2 Cells; Humans; Naphthoquinones; Neoplasms; Quinazolines; Sulfonic Acids; Triazoles | 2013 |
1,2,3-triazole-substituted oleanolic Acid derivatives: synthesis and antiproliferative activity.
Topics: Cell Proliferation; Drug Screening Assays, Antitumor; Fibroblasts; HL-60 Cells; Humans; Neoplasms; Oleanolic Acid; Structure-Activity Relationship; Triazoles | 2013 |
Treatment of invasive fungal infections in cancer patients-updated recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO).
Topics: Amphotericin B; Antifungal Agents; Candidiasis, Invasive; Catheter-Related Infections; Chemotherapy-Induced Febrile Neutropenia; Clinical Trials as Topic; Combined Modality Therapy; Drug Monitoring; Drug Therapy, Combination; Echinocandins; Fungemia; Humans; Immunocompromised Host; Immunotherapy; Invasive Pulmonary Aspergillosis; Mycoses; Neoplasms; Salvage Therapy; Triazoles | 2014 |
[Effectiveness of the correction of hepatotoxicity during combined chemoradiotherapy for cancer patients].
Topics: Adult; Aged; Brain Neoplasms; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Chemoradiotherapy; Drug Administration Schedule; Female; Glioma; Humans; Infusions, Intravenous; Liver; Male; Middle Aged; Neoplasms; Protective Agents; Severity of Illness Index; Treatment Outcome; Triazoles | 2013 |
Safe and easy route for the synthesis of 1,3-dimethyl-1,2,3-triazolium salt and investigation of its anticancer activities.
Topics: Antineoplastic Agents; Cell Line, Tumor; Humans; Methylation; Neoplasms; Triazoles | 2013 |
Discovery of 4-amino-2-(thio)phenol derivatives as novel protein kinase and angiogenesis inhibitors for the treatment of cancer: synthesis and biological evaluation. Part II.
Topics: Angiogenesis Inhibitors; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Drug Discovery; Human Umbilical Vein Endothelial Cells; Humans; Male; Models, Molecular; Molecular Structure; Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides; Triazoles; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
The HSP90 inhibitor ganetespib synergizes with the MET kinase inhibitor crizotinib in both crizotinib-sensitive and -resistant MET-driven tumor models.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Cells, Cultured; Crizotinib; Drug Resistance, Neoplasm; Drug Synergism; Female; HEK293 Cells; HSP90 Heat-Shock Proteins; Humans; Mice; Mice, Nude; Neoplasms; NIH 3T3 Cells; Proto-Oncogene Mas; Proto-Oncogene Proteins c-met; Pyrazoles; Pyridines; Triazoles; Xenograft Model Antitumor Assays | 2013 |
Fertility preservation with ovarian stimulation protocols prior to cancer treatment.
Topics: Aromatase Inhibitors; Estrogen Antagonists; Female; Fertility Preservation; Gonadotropins; Humans; Letrozole; Neoplasms; Neoplasms, Hormone-Dependent; Nitriles; Ovulation Induction; Precision Medicine; Tamoxifen; Time-to-Treatment; Triazoles | 2014 |
1,2,4-Triazole/oxime hybrids as new strategy for nitric oxide donors: Synthesis, anti-inflammatory, ulceroginicity and antiproliferative activities.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Edema; Humans; Male; Neoplasms; Nitric Oxide Donors; Oximes; Rats; Stomach Ulcer; Triazoles | 2014 |
Design and synthesis of anti-cancer cyclopeptides containing triazole skeleton.
Topics: Amino Acid Sequence; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Humans; Molecular Sequence Data; Molecular Structure; Neoplasms; Peptides, Cyclic; Triazoles | 2014 |
Regulation of MYC expression and differential JQ1 sensitivity in cancer cells.
Topics: Azepines; Blotting, Western; Burkitt Lymphoma; Cell Cycle Proteins; Chromatin Immunoprecipitation; Gene Expression Regulation, Neoplastic; Humans; Mediator Complex; Neoplasms; Nuclear Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA Polymerase II; RNA, Messenger; Transcription Factors; Triazoles; Tumor Cells, Cultured | 2014 |
Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII.
Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Enzyme Activation; Humans; Neoplasms; Protein Binding; Structure-Activity Relationship; Sulfonamides; Triazoles | 2014 |
6-Triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrases IX and XII.
Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Coumarins; Enzyme Activation; Humans; Neoplasms; Protein Binding; Triazoles | 2014 |
Synthesis and antiproliferative activity of some novel triazole derivatives from dehydroabietic acid.
Topics: Abietanes; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Fibroblasts; Humans; Neoplasms; Structure-Activity Relationship; Triazoles | 2014 |
Discovery of novel P-glycoprotein-mediated multidrug resistance inhibitors bearing triazole core via click chemistry.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzamides; Click Chemistry; Doxorubicin; Drug Resistance, Multiple; Humans; K562 Cells; Neoplasms; Triazoles | 2014 |
Review: voriconazole for prevention or treatment of invasive fungal infections in cancer with neutropenia.
Topics: Amphotericin B; Antifungal Agents; Humans; Mycoses; Neoplasms; Neutropenia; Opportunistic Infections; Pyrimidines; Triazoles | 2014 |
PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies.
Topics: Animals; Azepines; Cell Cycle Proteins; Cell Death; Chromatin; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioma; Humans; Melanoma; Mice; Mitogen-Activated Protein Kinase Kinases; Neoplasm Proteins; Neoplasms; Nerve Sheath Neoplasms; Neurofibromin 1; Nuclear Proteins; Polycomb Repressive Complex 2; ras Proteins; Transcription Factors; Transcription, Genetic; Triazoles; Tumor Suppressor Proteins | 2014 |
Enhanced two-photon fluorescence imaging and therapy of cancer cells via Gold@bridged silsesquioxane nanoparticles.
Topics: Cell Survival; Diagnostic Imaging; Fluorescence; Gold; Humans; MCF-7 Cells; Nanoparticles; Neoplasms; Organosilicon Compounds; Photochemotherapy; Photons; Quaternary Ammonium Compounds; Solubility; Spectrometry, Fluorescence; Triazoles | 2015 |
Design and synthesis of pironetin analogue/combretastatin A-4 hybrids containing a 1,2,3-triazole ring and evaluation of their cytotoxic activity.
Topics: Antineoplastic Agents, Phytogenic; Bibenzyls; Cell Proliferation; Cells, Cultured; Drug Design; Drug Screening Assays, Antitumor; Flow Cytometry; HEK293 Cells; Humans; Molecular Structure; Neoplasms; Pyrones; Structure-Activity Relationship; Triazoles | 2014 |
Design, synthesis and pharmacological screening of β-amino-, thiadiazole/thiadiazine-phosphonate based triazole motifs as antimicrobial/cytotoxic agents.
Topics: Anti-Infective Agents; Antineoplastic Agents; Cell Survival; Computer-Aided Design; Dose-Response Relationship, Drug; Drug Design; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Hep G2 Cells; Humans; Inhibitory Concentration 50; Male; MCF-7 Cells; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Neoplasms; Organophosphonates; Structure-Activity Relationship; Thiadiazines; Thiadiazoles; Triazoles | 2014 |
Design and synthesis of isosteviol triazole conjugates for cancer therapy.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Cytotoxins; Diterpenes, Kaurane; Humans; Neoplasms; Triazoles | 2014 |
Design of new hybrid template by linking quinoline, triazole and dihydroquinoline pharmacophoric groups: A greener approach to novel polyazaheterocycles as cytotoxic agents.
Topics: Antineoplastic Agents; Aza Compounds; Azides; Cell Line, Tumor; Drug Design; Green Chemistry Technology; Humans; Molecular Docking Simulation; Neoplasms; Phosphodiesterase 4 Inhibitors; Quinolines; Triazoles | 2015 |
Design and synthesis of novel 1,2,3-triazole-pyrimidine-urea hybrids as potential anticancer agents.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Humans; Neoplasms; Pyrimidines; Structure-Activity Relationship; Triazoles; Urea | 2015 |
Antifungal prophylaxis with posaconazole vs. fluconazole or itraconazole in pediatric patients with neutropenia.
Topics: Adolescent; Antifungal Agents; Chemoprevention; Child; Child, Preschool; Cohort Studies; Drug-Related Side Effects and Adverse Reactions; Female; Fluconazole; Humans; Incidence; Infant; Itraconazole; Male; Mycoses; Neoplasms; Neutropenia; Retrospective Studies; Treatment Outcome; Triazoles | 2015 |
Efficacy of random-start controlled ovarian stimulation in cancer patients.
Topics: Cryopreservation; Estradiol; Female; Fertility Preservation; Fertilization in Vitro; Humans; Infertility, Female; Letrozole; Neoplasms; Nitriles; Oocyte Retrieval; Ovulation Induction; Retrospective Studies; Triazoles | 2015 |
JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azepines; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Membrane Potential, Mitochondrial; Mice; Necrosis; Neoplasm Metastasis; Neoplasms; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Proto-Oncogene Proteins c-myc; Reactive Oxygen Species; RNA Interference; Transcriptome; Triazoles | 2015 |
Synthesis, antiproliferative and antifungal activities of 1,2,3-triazole-substituted carnosic Acid and carnosol derivatives.
Topics: Abietanes; Antifungal Agents; Candida albicans; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Cryptococcus neoformans; Fibroblasts; Humans; Microbial Sensitivity Tests; Neoplasms; Plant Extracts; Structure-Activity Relationship; Triazoles | 2015 |
PI3K target based novel cyano derivative of betulinic acid induces its signalling inhibition by down-regulation of pGSK3β and cyclin D1 and potentially checks cancer cell proliferation.
Topics: Betulinic Acid; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Down-Regulation; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HL-60 Cells; Humans; MCF-7 Cells; Neoplasms; Pentacyclic Triterpenes; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Signal Transduction; Triazoles; Triterpenes | 2016 |
A nude mouse model of obesity to study the mechanisms of resistance to aromatase inhibitors.
Topics: Adipose Tissue; Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Blood Glucose; Cell Line, Tumor; Cyclooxygenase 2; Diet; Disease Models, Animal; Drug Resistance, Neoplasm; Estrogens; Humans; Insulin; Letrozole; Mice, Nude; Neoplasms; Nitriles; Obesity; Ovariectomy; Triazoles; Tumor Burden | 2015 |
HSP90 Inhibitor-SN-38 Conjugate Strategy for Targeted Delivery of Topoisomerase I Inhibitor to Tumors.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Camptothecin; Cell Line, Tumor; Female; HSP90 Heat-Shock Proteins; Humans; Irinotecan; Mice, Inbred ICR; Mice, SCID; Microscopy, Fluorescence; Molecular Targeted Therapy; Neoplasms; Resorcinols; Topoisomerase I Inhibitors; Treatment Outcome; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
The BET bromodomain inhibitor, JQ1, facilitates c-FLIP degradation and enhances TRAIL-induced apoptosis independent of BRD4 and c-Myc inhibition.
Topics: Antineoplastic Agents; Apoptosis; Azepines; Blotting, Western; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Cycle Proteins; Cell Line, Tumor; Gene Knockdown Techniques; Humans; Neoplasms; Nuclear Proteins; Proto-Oncogene Proteins c-myc; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand; Transcription Factors; Transfection; Triazoles | 2015 |
c-Myc alterations confer therapeutic response and acquired resistance to c-Met inhibitors in MET-addicted cancers.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Gefitinib; Humans; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Proto-Oncogene Proteins c-myc; Pyridazines; Quinazolines; RNA Interference; RNA, Small Interfering; Triazoles; Xenograft Model Antitumor Assays | 2015 |
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance.
Topics: Animals; Antineoplastic Agents; Benzeneacetamides; beta Catenin; Brain Neoplasms; Camptothecin; Celecoxib; Cisplatin; Colorectal Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Glucose-6-Phosphate Isomerase; Heterocyclic Compounds, 3-Ring; Humans; Immunoblotting; Immunohistochemistry; Irinotecan; Medulloblastoma; Mice; Neoplasm Transplantation; Neoplasms; Neuroblastoma; Pyrans; Pyrazines; Pyridines; Real-Time Polymerase Chain Reaction; Sulfones; Temozolomide; Triazoles; Tumor Suppressor Proteins; Vincristine; Wnt Proteins; Wnt Signaling Pathway | 2015 |
Comparison of posaconazole serum concentrations from haematological cancer patients on posaconazole tablet and oral suspension for treatment and prevention of invasive fungal infections.
Topics: Adult; Aged; Antifungal Agents; Chemoprevention; Female; Humans; Invasive Fungal Infections; Male; Middle Aged; Neoplasms; Retrospective Studies; Serum; Suspensions; Tablets; Triazoles; Young Adult | 2016 |
Synthesis and Biological Evaluation of 1,2,3-triazole tethered Pyrazoline and Chalcone Derivatives.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chalcones; Drug Design; Female; G2 Phase; Humans; Male; Membrane Potential, Mitochondrial; Models, Molecular; Molecular Structure; Neoplasms; Polymerization; Pyrazoles; Triazoles; Tubulin; Tubulin Modulators | 2016 |
Discovery of novel pyrrolo[2,3-b]pyridine derivatives bearing 1,2,3-triazole moiety as c-Met kinase inhibitors.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Docking Simulation; Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridines; Pyrroles; Structure-Activity Relationship; Triazoles | 2016 |
Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell.
Topics: Antineoplastic Agents; Aurora Kinase A; Benzenesulfonates; Calorimetry; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; DNA Damage; Escherichia coli; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microtubule-Associated Proteins; Neoplasms; Nuclear Proteins; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins; Rad51 Recombinase; Thermodynamics; Triazoles; Tumor Suppressor Protein p53 | 2016 |
Chemical probes: A shared toolbox.
Topics: Access to Information; Animals; Azepines; Clinical Trials as Topic; Drug Discovery; Histones; Humans; Information Dissemination; Male; Mice; Neoplasms; Patents as Topic; Protein Binding; Protein Structure, Tertiary; Triazoles; Xenograft Model Antitumor Assays | 2016 |
Synthesis and in Vitro Antiproliferative Evaluation of C-13 Epimers of Triazolyl-d-Secoestrone Alcohols: The First Potent 13α-d-Secoestrone Derivative.
Topics: Alcohols; Alkynes; Azides; Catalysis; Cell Cycle; Cell Proliferation; Cycloaddition Reaction; Humans; MCF-7 Cells; Neoplasms; Triazoles | 2016 |
Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors.
Topics: Azepines; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Chromatin; Cyclin-Dependent Kinase 9; E2F Transcription Factors; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Nuclear Proteins; Promoter Regions, Genetic; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-myc; RNA Polymerase II; Transcription Factors; Transcription, Genetic; Triazoles | 2017 |
BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression.
Topics: Animals; Azepines; B7-H1 Antigen; Cell Cycle Proteins; Cell Line, Tumor; Disease Progression; Female; Humans; Immunity; Mice, Inbred C57BL; Neoplasms; Nuclear Proteins; Proteins; T-Lymphocytes, Cytotoxic; Time Factors; Transcription Factors; Transcription, Genetic; Triazoles | 2016 |
Syntheses, cytotoxic activity evaluation and HQSAR study of 1,2,3-triazole-linked isosteviol derivatives as potential anticancer agents.
Topics: Antineoplastic Agents; Cell Survival; Click Chemistry; Diterpenes, Kaurane; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Models, Molecular; Neoplasms; Quantitative Structure-Activity Relationship; Triazoles | 2016 |
Design, synthesis, and biological evaluation of novel alkylsulfanyl-1,2,4-triazoles as cis-restricted combretastatin A-4 analogues.
Topics: Antineoplastic Agents; Bibenzyls; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Neoplasms; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2017 |
Targeting Cancer at the Nuclear Pore.
Topics: Animals; Antineoplastic Agents; Exportin 1 Protein; Gene Expression Regulation, Neoplastic; Humans; Hydrazines; Karyopherins; Molecular Targeted Therapy; Neoplasms; Nuclear Pore; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Treatment Outcome; Triazoles | 2016 |
Novel pyrimidine-2,4-dione-1,2,3-triazole and furo[2,3-d]pyrimidine-2-one-1,2,3-triazole hybrids as potential anti-cancer agents: Synthesis, computational and X-ray analysis and biological evaluation.
Topics: Antineoplastic Agents; Catalysis; Cell Cycle Proteins; Crystallography, X-Ray; Cyclization; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Models, Molecular; Neoplasms; Nuclear Proteins; Protein-Tyrosine Kinases; Pyrimidines; Signal Transduction; Sphingolipids; Triazoles | 2017 |
Prospective identification of resistance mechanisms to HSP90 inhibition in KRAS mutant cancer cells.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Benzodioxoles; Benzoquinones; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Amplification; Genetic Predisposition to Disease; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Mutation; Mutation, Missense; Neoplasms; Phenotype; Proto-Oncogene Proteins p21(ras); Purines; RNA Interference; Transfection; Triazoles | 2017 |
A Conversation with Christopher Vakoc.
Topics: Azepines; Genes, myc; Humans; Neoplasms; Oncogenes; Research; Triazoles | 2016 |
The Exportin-1 Inhibitor Selinexor Exerts Superior Antitumor Activity when Combined with T-Cell Checkpoint Inhibitors.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; B7-H1 Antigen; Cell Line, Tumor; CTLA-4 Antigen; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Exportin 1 Protein; Humans; Hydrazines; Immunomodulation; Karyopherins; Melanoma, Experimental; Mice; Neoplasms; Receptors, Cytoplasmic and Nuclear; T-Lymphocytes; Triazoles | 2017 |
Engineering a Multifunctional Nitroreductase for Improved Activation of Prodrugs and PET Probes for Cancer Gene Therapy.
Topics: Binding Sites; Cell Line, Tumor; Escherichia coli; Escherichia coli Proteins; Etanidazole; HCT116 Cells; Humans; Hydrocarbons, Fluorinated; Imidazoles; Inhibitory Concentration 50; Metronidazole; Molecular Docking Simulation; Mutagenesis, Site-Directed; Neoplasms; Nitrogen Mustard Compounds; Nitroreductases; Positron-Emission Tomography; Prodrugs; Protein Structure, Tertiary; Substrate Specificity; Triazoles | 2017 |
Investigation and management of an outbreak of mucormycosis in a paediatric oncology unit.
Topics: Adolescent; Antifungal Agents; Chemoprevention; Cross Infection; Disease Outbreaks; Environmental Microbiology; Hospital Units; Hospitals, University; Humans; Infant; Infection Control; Male; Mucormycosis; Neoplasms; Triazoles | 2008 |
Use of a novel Arg-Gly-Asp radioligand, 18F-AH111585, to determine changes in tumor vascularity after antitumor therapy.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Carcinoma, Non-Small-Cell Lung; Dose-Response Relationship, Drug; Mice; Neoplasms; Oligopeptides; Paclitaxel; Peptides; Polyethylene Glycols; Positron-Emission Tomography; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Tissue Distribution; Triazoles | 2009 |
Preservation of fertility in patients with cancer.
Topics: Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Fertility; Humans; Letrozole; Neoplasms; Nitriles; Ovary; Ovulation Induction; Recurrence; Time Factors; Triazoles | 2009 |
A FRET-based microplate assay for human protein kinase CK2, a target in neoplastic disease.
Topics: Casein Kinase II; Emodin; Enzyme Assays; Fluorescence; Fluorescence Resonance Energy Transfer; Humans; Naphthalenesulfonates; Neoplasms; p-Dimethylaminoazobenzene; Pancreatic Elastase; Peptides; Phosphorylation; Protein Kinase Inhibitors; Sensitivity and Specificity; Triazoles | 2010 |
Musculoskeletal manifestations in patients with malignant disease.
Topics: Adult; Aged; Analysis of Variance; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Humans; Joint Diseases; Letrozole; Male; Middle Aged; Muscular Diseases; Neoplasms; Nitriles; Osteoporosis; Statistics, Nonparametric; Triazoles | 2010 |
SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo.
Topics: Adenosine Triphosphate; Animals; Catalysis; Cell Line; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Mice; Mice, Nude; Models, Molecular; Molecular Structure; Neoplasms; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Secondary; Protein Structure, Tertiary; Proto-Oncogene Proteins c-met; Pyridazines; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays | 2009 |
Targeting the Hsp90 chaperone: synthesis of novel resorcylic acid macrolactone inhibitors of Hsp90.
Topics: Antineoplastic Agents; Binding Sites; Crystallography, X-Ray; HSP90 Heat-Shock Proteins; Humans; Macrolides; Neoplasms; Protein Binding; Triazoles | 2010 |
Differences in voriconazole trough plasma concentrations per oral dosages between children younger and older than 3 years of age.
Topics: Administration, Oral; Adolescent; Age Factors; Antifungal Agents; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infant; Infant, Newborn; Male; Mycoses; Neoplasms; Pyrimidines; Triazoles; Voriconazole | 2010 |
Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).
Topics: Animals; Apoptosis; Area Under Curve; Cell Line; Cell Line, Tumor; Cells, Cultured; Crystallography, X-Ray; Enzyme Inhibitors; Female; Humans; Indoles; Inhibitory Concentration 50; Mice; Mice, Inbred C57BL; Mice, Nude; Models, Chemical; Models, Molecular; Molecular Structure; Mutation; Neoplasms; Protein Binding; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Salicylic Acid; Small Molecule Libraries; Triazoles; Xenograft Model Antitumor Assays | 2010 |
Modeling of diarylalkyl-imidazole and diarylalkyl-triazole derivatives as potent aromatase inhibitors for treatment of hormone-dependent cancer.
Topics: Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Computer Simulation; Energy Transfer; Hydrogen; Imidazoles; Ligands; Models, Chemical; Models, Molecular; Molecular Conformation; Neoplasms; Quantitative Structure-Activity Relationship; Triazoles | 2010 |
Synthesis of Tc-99m labeled 1,2,3-triazole-4-yl c-met binding peptide as a potential c-met receptor kinase positive tumor imaging agent.
Topics: Humans; Neoplasms; Proto-Oncogene Proteins c-met; Receptor Protein-Tyrosine Kinases; Technetium; Triazoles | 2010 |
[4+2] cycloaddition reactions between 1,8-disubstituted cyclooctatetraenes and diazo dienophiles: stereoelectronic effects, anticancer properties and application to the synthesis of 7,8-substituted bicyclo[4.2.0]octa-2,4-dienes.
Topics: Antineoplastic Agents; Azo Compounds; Bridged Bicyclo Compounds; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cyclization; Diterpenes; Humans; Microwaves; Models, Molecular; Molecular Structure; Neoplasms; Stereoisomerism; Triazoles | 2010 |
Pre-clinical evaluation of a 3-nitro-1,2,4-triazole analogue of [18F]FMISO as hypoxia-selective tracer for PET.
Topics: Animals; Biomarkers; Cell Hypoxia; Cell Line, Tumor; Cell Transformation, Neoplastic; Chemical Phenomena; Drug Evaluation, Preclinical; Female; Glutathione; Kinetics; Mice; Misonidazole; Models, Biological; Neoplasms; Oxidation-Reduction; Positron-Emission Tomography; Propanols; Radioactive Tracers; Triazoles; Xanthine Oxidase | 2010 |
Design, synthesis, and anticancer activities of novel perfluoroalkyltriazole-appended 2'-deoxyuridines.
Topics: Antineoplastic Agents; Cell Line, Tumor; Deoxyuridine; Drug Design; Fluorine; Humans; Neoplasms; Triazoles | 2010 |
Evaluation of treatment-effect heterogeneity using biomarkers measured on a continuous scale: subpopulation treatment effect pattern plot.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Female; Humans; Ki-67 Antigen; Letrozole; Models, Statistical; Neoplasms; Nitriles; Outcome Assessment, Health Care; Predictive Value of Tests; Prognosis; Reproducibility of Results; Tamoxifen; Triazoles | 2010 |
Posaconazole versus fluconazole or itraconazole for prevention of invasive fungal infections in patients undergoing intensive cytotoxic therapy for acute myeloid leukemia or myelodysplasia: a cost effectiveness analysis.
Topics: Antifungal Agents; Antineoplastic Agents; Canada; Cost Savings; Cost-Benefit Analysis; Decision Support Techniques; Fluconazole; Humans; Itraconazole; Leukemia, Myeloid, Acute; Models, Economic; Mycoses; Myelodysplastic Syndromes; Neoplasms; Randomized Controlled Trials as Topic; Triazoles | 2011 |
Synthesis, encapsulation and antitumor activity of new betulin derivatives.
Topics: Antineoplastic Agents; Betulinic Acid; Cell Line, Tumor; Colorimetry; Drug Screening Assays, Antitumor; Fluorescent Dyes; Humans; Liposomes; Neoplasms; Pentacyclic Triterpenes; Pyrazoles; Rhodamines; Structure-Activity Relationship; Triazoles; Triterpenes | 2011 |
A retrospective analysis of the effect of patient-specific factors on voriconazole concentrations in oncology patients.
Topics: Adult; Age Factors; Aged; Alkaline Phosphatase; Antifungal Agents; Female; Humans; International Normalized Ratio; Linear Models; Male; Middle Aged; Multivariate Analysis; Mycoses; Neoplasms; Pyrimidines; Retrospective Studies; Triazoles; Voriconazole; Young Adult | 2012 |
Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment.
Topics: Antineoplastic Agents; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Caspase 8; Cell Line, Tumor; Cell Survival; Death Domain Receptor Signaling Adaptor Proteins; Drug Synergism; Humans; Inhibitor of Apoptosis Proteins; Neoplasms; Nuclear Pore Complex Proteins; Protein Binding; RNA-Binding Proteins; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Triazoles; X-Linked Inhibitor of Apoptosis Protein | 2011 |
Platinum(IV) coordination compounds containing 5-methyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one as nonleaving ligand. Molecular and cytotoxicity in vitro characterization.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Humans; Ligands; Neoplasms; Organoplatinum Compounds; Pyrimidines; Triazoles | 2011 |
Synthesis of novel molecular probes inspired by harringtonolide.
Topics: Antineoplastic Agents, Phytogenic; Azides; Catalysis; Chemistry, Pharmaceutical; Click Chemistry; Copper; Cyclopentanes; Drug Discovery; Harringtonines; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Probes; Neoplasms; Plants, Medicinal; Small Molecule Libraries; Stereoisomerism; Taxaceae; Triazoles | 2011 |
Structure-based optimization of click-based histone deacetylase inhibitors.
Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Crystallography, X-Ray; Drug Design; Drug Screening Assays, Antitumor; Histone Deacetylase 1; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Hydroxamic Acids; Models, Molecular; Neoplasms; Phenylalanine; Protein Binding; Protein Structure, Secondary; Structure-Activity Relationship; Triazoles; Vorinostat | 2011 |
One-pot synthesis of an 125I-labeled trifunctional reagent for multiscale imaging with optical and nuclear techniques.
Topics: Animals; Antibodies, Monoclonal; Carcinoembryonic Antigen; Click Chemistry; Copper; Diagnostic Imaging; Fluorescence; Humans; Indium Radioisotopes; Mice; Neoplasms; Triazoles | 2011 |
Inhibition of pro-inflammatory cytokines in tumour associated macrophages is a potential anti-cancer mechanism of carboxyamidotriazole.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Arthritis, Experimental; Carcinoma, Lewis Lung; Coculture Techniques; Cytokines; Dexamethasone; Macrophages; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms; Rats, Wistar; Triazoles; Tumor Microenvironment; Tumor Necrosis Factor-alpha | 2012 |
7-(4H-1,2,4-Triazol-3-yl)benzo[c][2,6]naphthyridines: a novel class of Pim kinase inhibitors with potent cell antiproliferative activity.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Leukemia; Naphthyridines; Neoplasms; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-pim-1; Triazoles | 2011 |
First drugs found to inhibit elusive cancer target.
Topics: Animals; Antineoplastic Agents; Azepines; Cell Cycle Proteins; Humans; Mice; Neoplasms; Nuclear Proteins; Proto-Oncogene Proteins c-myc; Transcription Factors; Triazoles | 2011 |
Phase I evaluation of STA-1474, a prodrug of the novel HSP90 inhibitor ganetespib, in dogs with spontaneous cancer.
Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Dogs; Female; HSP90 Heat-Shock Proteins; Indoles; Male; Neoplasms; Prodrugs; Tandem Mass Spectrometry; Triazoles | 2011 |
Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzoquinones; Blotting, Western; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Crystallography, X-Ray; Female; Heart; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; K562 Cells; Lactams, Macrocyclic; Male; Mice; Mice, Nude; Mice, SCID; Neoplasms; Rabbits; Rats; Rats, Sprague-Dawley; Triazoles; Xenograft Model Antitumor Assays | 2012 |
Blocking S1P interaction with S1P₁ receptor by a novel competitive S1P₁-selective antagonist inhibits angiogenesis.
Topics: Cell Line, Tumor; Human Umbilical Vein Endothelial Cells; Humans; Lysophospholipids; Neoplasms; Neovascularization, Pathologic; Neovascularization, Physiologic; Receptors, Lysosphingolipid; Sphingosine; Sphingosine-1-Phosphate Receptors; Sulfones; Triazoles; Vascular Endothelial Growth Factor A | 2012 |
Idiosyncratic nature of voriconazole photosensitivity in children undergoing cancer therapy.
Topics: Antifungal Agents; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Humans; Male; Mycoses; Neoplasms; Photosensitivity Disorders; Pyrimidines; Triazoles; Voriconazole | 2012 |
Growth suppression and mitotic defect induced by JNJ-7706621, an inhibitor of cyclin-dependent kinases and aurora kinases.
Topics: Animals; Antineoplastic Agents; Aurora Kinase A; Aurora Kinase B; Aurora Kinases; Bone Neoplasms; Cell Cycle Checkpoints; Cell Proliferation; Cyclin-Dependent Kinases; Cytokinesis; Dose-Response Relationship, Drug; HeLa Cells; Humans; Mice; Mice, Nude; Mitosis; Neoplasms; Nocodazole; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Sarcoma, Ewing; Spindle Apparatus; Time Factors; Triazoles; Tubulin Modulators; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
Voriconazole-induced phototoxicity in children.
Topics: Chemoprevention; Child; Child, Preschool; Dermatitis, Phototoxic; Female; Humans; Immunocompromised Host; Incidence; Infant; Male; Mycoses; Neoplasms; Pyrimidines; Retrospective Studies; Risk Assessment; Triazoles; Voriconazole | 2012 |
Benzimidazole bearing oxadiazole and triazolo-thiadiazoles nucleus: design and synthesis as anticancer agents.
Topics: Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Humans; Neoplasms; Oxadiazoles; Thiadiazoles; Triazoles | 2012 |
Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Isoxazoles; Neoplasms; Structure-Activity Relationship; Thiazoles; Triazoles | 2012 |
Cancer research: Open ambition.
Topics: Adult; Animals; Azepines; Benzodiazepines; Cell Cycle Proteins; Child; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Leukemia; Male; Mice; Mutation; Neoplasm Proteins; Neoplasms; Nuclear Proteins; Oncogene Proteins; Oncogene Proteins, Fusion; Proto-Oncogene Proteins c-myc; Transcription Factors; Triazoles; Vorinostat; Young Adult | 2012 |
Novel coumarin derivatives containing 1,2,4-triazole, 4,5-dicyanoimidazole and purine moieties: synthesis and evaluation of their cytostatic activity.
Topics: Antineoplastic Agents; Cell Line, Tumor; Coumarins; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Imidazoles; MCF-7 Cells; Molecular Structure; Neoplasms; Nucleosides; Purines; Structure-Activity Relationship; Triazoles | 2012 |
Syntheses, characterization, and antitumor activities of platinum(II) and palladium(II) complexes with sugar-conjugated triazole ligands.
Topics: Antineoplastic Agents; Carbohydrates; Cisplatin; Coordination Complexes; Crystallography, X-Ray; HeLa Cells; Humans; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Neoplasms; Palladium; Platinum; Triazoles | 2012 |
Alkylsulfanyl-1,2,4-triazoles, a new class of allosteric valosine containing protein inhibitors. Synthesis and structure-activity relationships.
Topics: Adenosine Triphosphatases; Allosteric Regulation; Cell Cycle Proteins; Humans; Neoplasms; Structure-Activity Relationship; Triazoles; Valosin Containing Protein | 2013 |
Prospective epidemiologic analysis of triazole-resistant nosocomial Candida glabrata isolated from patients at a comprehensive cancer center.
Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Candida glabrata; Candidiasis; Cross Infection; Drug Resistance, Fungal; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Neoplasms; Prospective Studies; Random Amplified Polymorphic DNA Technique; Triazoles | 2002 |
Use of 3-amino-1,2,4-triazole to reduce body catalase activity in cancer studies.
Topics: Amitrole; Antithyroid Agents; Azoles; Catalase; Neoplasms; Oxidation-Reduction; Triazoles | 1959 |
[The development and evaluation of fungistatic compounds in the treatment of cancer. 2].
Topics: Antifungal Agents; Antineoplastic Agents; Humans; Neoplasms; Neoplasms, Experimental; Triazoles | 1963 |
[The development and evaluation of fungistatic compounds in the treatment of cancer. I].
Topics: Antifungal Agents; Antineoplastic Agents; Humans; Neoplasms; Triazoles | 1962 |
ON SOME NEW ASPECTS OF EXPERIMENTAL CARCINOGENESIS THYROID GLAND.
Topics: Carcinogenesis; Methylthiouracil; Neoplasms; Neoplasms, Experimental; Rats; Research; Thyroid Neoplasms; Triazoles | 1963 |
[CHEMICAL AND PHARMACOLOGICAL STUDY OF NITROFURAZONE ANALOGUES WITH RESPECT TO THEIR THERAPEUTIC ACTION ON MALIGNANT EMBRYOMA OF THE TESTIS].
Topics: Antineoplastic Agents; Humans; Lung Neoplasms; Male; Mice; Neoplasm Metastasis; Neoplasms; Nitrofurazone; Pharmacology; Rats; Research; Teratoma; Testicular Neoplasms; Thiosemicarbazones; Triazoles | 1964 |
Studies on the mechanism of catalase depression by toxohormone, with the aid of allylisopropylacetamide, allylisopropylacetylcarbamide, and 3-amino-1,2,4-triazole.
Topics: Allylisopropylacetamide; Amides; Amitrole; Azoles; Catalase; Depression; Depressive Disorder; Endotoxins; Hypnotics and Sedatives; Neoplasms; Triazoles; Urea | 1962 |
Salvage therapy with voriconazole for invasive fungal infections in patients failing or intolerant to standard antifungal therapy.
Topics: Adult; Aged; Antifungal Agents; Aspergillosis; Bone Marrow Transplantation; Child; Drug Resistance, Fungal; Female; Hematologic Neoplasms; Humans; Immunocompromised Host; Middle Aged; Mycoses; Neoplasms; Pyrimidines; Salvage Therapy; Transplantation; Treatment Failure; Triazoles; Voriconazole | 2003 |
Prevention strategies with aromatase inhibitors.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Female; Humans; Isoenzymes; Membrane Proteins; Models, Biological; Neoplasms; Nitriles; Placebos; Postmenopause; Prostaglandin-Endoperoxide Synthases; Receptors, Estrogen; Tamoxifen; Time Factors; Triazoles | 2004 |
Diagnosing invasive aspergillosis during antifungal therapy by PCR analysis of blood samples.
Topics: Adult; Aged; Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus; Base Sequence; Bronchoalveolar Lavage Fluid; DNA Primers; DNA, Fungal; Humans; Leukemia; Middle Aged; Neoplasms; Polymerase Chain Reaction; Pyrimidines; Transplantation; Triazoles; Voriconazole | 2004 |
Antifungal therapy in patients with fever and neutropenia--more rational and less empirical?
Topics: Amphotericin B; Antifungal Agents; Caspofungin; Echinocandins; Fever; Humans; Lipopeptides; Liposomes; Mycoses; Neoplasms; Neutropenia; Peptides; Peptides, Cyclic; Pyrimidines; Triazoles; Voriconazole | 2004 |
Subchronic acrylamide treatment induces a tissue-specific increase in DNA synthesis in the rat.
Topics: Acrylamide; Animals; Apoptosis; Bromodeoxyuridine; Cell Division; DNA; Dose-Response Relationship, Drug; Drug Therapy, Combination; Environmental Pollutants; Male; Mitosis; Neoplasms; Organ Specificity; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Triazoles | 2004 |
Preparation and preliminary biological evaluation of a 177Lu labeled sanazole derivative for possible use in targeting tumor hypoxia.
Topics: Animals; Antineoplastic Agents; Drug Delivery Systems; Fibrosarcoma; Hypoxia; Lutetium; Mice; Neoplasms; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Triazoles | 2004 |
[Drugs used in prophylaxis and treatment of fungal infections in immunosuppressed children].
Topics: Antifungal Agents; Aspergillosis; Candidiasis; Caspofungin; Child; Drug Resistance, Fungal; Echinocandins; Humans; Immunocompromised Host; Lipopeptides; Mycoses; Neoplasms; Peptides, Cyclic; Pyrimidines; Risk Factors; Triazoles; Voriconazole | 2004 |
Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols.
Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cytosol; Enzyme Inhibitors; Humans; Kinetics; Models, Molecular; Molecular Structure; Neoplasms; Structure-Activity Relationship; Sulfhydryl Compounds; Thiadiazoles; Triazoles | 2005 |
Increased frequency of non-fumigatus Aspergillus species in amphotericin B- or triazole-pre-exposed cancer patients with positive cultures for aspergilli.
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus; Chemoprevention; Culture Media; Drug Resistance, Fungal; Humans; Microbial Sensitivity Tests; Neoplasms; Triazoles | 2005 |
Voriconazole susceptibility of yeasts isolated from the mouths of patients with advanced cancer.
Topics: Antifungal Agents; Drug Resistance, Fungal; Fluconazole; Humans; Itraconazole; Microbial Sensitivity Tests; Mouth Diseases; Mycoses; Neoplasms; Palliative Care; Pyrimidines; Triazoles; Voriconazole; Yeasts | 2005 |
Options for preservation of fertility in women.
Topics: Algorithms; Antineoplastic Agents; Breast Neoplasms; Cryopreservation; Drug Therapy, Combination; Embryo, Mammalian; Female; Fertility; Gonadotropins; Humans; Letrozole; Neoplasms; Nitriles; Ovary; Tamoxifen; Transplantation, Heterotopic; Triazoles | 2005 |
Evaluation of antiangiogenic treatment effects on tumors' microcirculation by Bayesian physiological pharmacokinetic modeling and magnetic resonance imaging.
Topics: Animals; Bayes Theorem; Contrast Media; Heterocyclic Compounds; Magnetic Resonance Imaging; Male; Mice; Mice, Nude; Microcirculation; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Organometallic Compounds; Quinazolines; Triazoles; Xenograft Model Antitumor Assays | 2006 |
Random plasma concentrations of voriconazole decline over time.
Topics: Antifungal Agents; Female; Humans; Male; Middle Aged; Neoplasms; Plasma; Pyrimidines; Retrospective Studies; Time Factors; Triazoles; Voriconazole | 2007 |
Management of comorbid diabetes and cancer.
Topics: Ambulatory Care; Amyloid; Comorbidity; Diabetes Mellitus; Exenatide; Humans; Hypoglycemic Agents; Inpatients; Insulin; Islet Amyloid Polypeptide; Neoplasms; Peptides; Practice Guidelines as Topic; Pyrazines; Quality of Life; Risk Factors; Sitagliptin Phosphate; Treatment Outcome; Triazoles; Venoms | 2007 |
Neutral 5-substituted 4-anilinoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinase.
Topics: Administration, Oral; Aniline Compounds; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Dogs; Drug Synergism; Mice; Molecular Structure; Neoplasms; Quinazolines; Rats; Receptor, ErbB-2; Triazoles; Xenograft Model Antitumor Assays | 2007 |
Synthesis of 1,2,3-triazole-linked pyrrolobenzodiazepine conjugates employing 'click' chemistry: DNA-binding affinity and anticancer activity.
Topics: Antineoplastic Agents; Benzodiazepines; Cell Line, Tumor; DNA; Humans; Kinetics; Neoplasms; Pyrroles; Triazoles | 2008 |
Selective sensitivity to carboxyamidotriazole by human tumor cell lines with DNA mismatch repair deficiency.
Topics: Antineoplastic Agents; Apoptosis; Calcium Channel Blockers; Cell Cycle; Cell Line, Tumor; Chromosomes, Human; Colonic Neoplasms; Colorimetry; DNA Mismatch Repair; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Male; Neoplasm Invasiveness; Neoplasms; Nifedipine; Ovarian Neoplasms; Prostatic Neoplasms; Transfection; Triazoles; Urinary Bladder Neoplasms | 2008 |
alpha-/beta-Triglycidyl-urazol (TGU, NSC 332488, I.N.N.: ANAXIRONE): a new chemotherapeutic agent.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Drug Evaluation; Drug Evaluation, Preclinical; Humans; Kinetics; Metabolic Clearance Rate; Mice; Neoplasms; Neoplasms, Experimental; Rats; Triazines; Triazoles | 1984 |
Interferon-gamma-induced membrane PAF-receptor expression confers tumor cell susceptibility to NK perforin-dependent lysis.
Topics: Adult; Azepines; Calcium; Cell Membrane; Cytotoxicity, Immunologic; Gene Expression; Humans; Interferon-gamma; Killer Cells, Natural; Membrane Glycoproteins; Neoplasms; Perforin; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pore Forming Cytotoxic Proteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Transfection; Triazoles; Tumor Cells, Cultured | 2000 |
Is there in vivo-in vitro correlation between antifungal susceptibility, species of Candida spp. and clinical outcome?
Topics: Antifungal Agents; Candida; Candidiasis; Clinical Trials as Topic; HIV Infections; Humans; Microbial Sensitivity Tests; Neoplasms; Statistics as Topic; Treatment Outcome; Triazoles | 2000 |
Technetium-99m-cyclam AK 2123: a novel marker for tumor hypoxia.
Topics: Animals; Cell Hypoxia; Female; Lung Neoplasms; Mammary Neoplasms, Experimental; Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Tissue Distribution; Triazoles | 2001 |
In vitro activity of three new triazoles and one echinocandin against Candida bloodstream isolates from cancer patients.
Topics: Antifungal Agents; Blood; Candida; Candidiasis; Echinocandins; Humans; In Vitro Techniques; Lipopeptides; Lipoproteins; Micafungin; Microbial Sensitivity Tests; Neoplasms; Peptides, Cyclic; Pyrimidines; Thiazoles; Triazoles; Voriconazole | 2002 |
Photocarcinogenesis: lack of enhancement by fluorescent white agents.
Topics: Animals; Biphenyl Compounds; Coloring Agents; Humans; Light; Male; Mice; Mice, Nude; Neoplasms; Skin; Stilbenes; Swine; Triazoles; Ultraviolet Rays | 1975 |
Phase-II studies of 1,2,4-triglycidylurazol (TGU) in solid tumors. Phase-II Study Group of the Association of Medical Oncology of the German Cancer Society.
Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; Humans; Male; Middle Aged; Neoplasms; Prognosis; Triazoles | 1986 |
Phase I study of triglycidylurazol given on a 5-day i.v. schedule.
Topics: Adult; Aged; Anemia; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Female; Humans; Injections, Intravenous; Leukopenia; Male; Middle Aged; Neoplasms; Thrombocytopenia; Triazoles | 1986 |
A clinical and pharmacokinetic phase I study of 1,2,4-triglycidylurazol (TGU, NSC 332488).
Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; Humans; Kinetics; Male; Middle Aged; Neoplasms; Triazoles | 1986 |
Phase I trial of 1,2,4-triglycidylurazol (TGU, NSC 332488): a new triepoxide cytostatic agent.
Topics: Adult; Aged; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Leukopenia; Male; Middle Aged; Neoplasms; Phlebitis; Thrombocytopenia; Triazoles | 1985 |
Triamiphos: long-term toxicity and three-generation reproduction studies in rats.
Topics: Animals; Blood Cell Count; Body Weight; Brain; Cholinesterase Inhibitors; Cholinesterases; Dimethylamines; Eating; Erythrocytes; Female; Fertility; Germ-Free Life; Growth; Hemoglobins; Insecticides; Male; Neoplasms; Organ Size; Organophosphorus Compounds; Rats; Reproduction; Time Factors; Triazoles | 1974 |
The inhibition of catalase by plasma and by human tissue extracts.
Topics: Ascorbic Acid; Blood; Carcinoma; Catalase; Conductometry; Dialysis; Edetic Acid; Erythrocytes; Ethylmaleimide; Hemolysis; Hot Temperature; Humans; Kidney; Liver; Lung Neoplasms; Male; Neoplasms; Prostatic Neoplasms; Stomach Neoplasms; Tissue Extracts; Triazoles | 1969 |
Differential sensitivity of human normal and malignant cells to 8-azahypoxanthine in vitro.
Topics: Animals; Cattle; Cell Line; Cells, Cultured; Clone Cells; Culture Media; Culture Techniques; Diploidy; Fibroblasts; HeLa Cells; Humans; Hypoxanthines; Infant, Newborn; Male; Neoplasms; Phosphotransferases; Polyploidy; Purines; Pyrimidinones; Serum Albumin, Bovine; Triazoles | 1971 |