Page last updated: 2024-08-24

triazoles and Aura

triazoles has been researched along with Aura in 82 studies

Research

Studies (82)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.44)	18.7374
1990's	13 (15.85)	18.2507
2000's	22 (26.83)	29.6817
2010's	36 (43.90)	24.3611
2020's	9 (10.98)	2.80

Authors

Authors	Studies
Liu, D; Wang, Y	1
Chen, L; Hou, Z; Huang, L; Li, X; Lian, C; Meng, Q; Wang, Y; Wu, J; Yu, H; Zhang, C	1
Imai, K; Inoue, Y; Kagawa, Y; Takahashi, Y; Usui, N; Yamamoto, Y	1
Abou Tayoun, A; Goldberg, EM; Zaman, T	1
Bozarth, XL; Oesch, G	1
Barbieri, R; Bertelli, S; Gavazzo, P; Pusch, M	1
Cummins, TR; Mason, ER	1
Andrys, R; Angeli, A; Czarnomysy, R; Kaproń, B; Musilek, K; Plech, T; Supuran, CT; Wysokiński, M	1
Caraballo, RH; Espeche, A; Fasulo, L; Galichio, S; Pociecha, J; Reyes, G; Semprino, M	1
Beccaria, F; Capovilla, G; De Giorgis, V; Fattore, C; Franco, V; Galimberti, CA; Gatti, G; Johannessen Landmark, C; Marchiselli, R; Mazzucchelli, I; Perucca, E; Rota, P	1
Loddenkemper, T; Tanritanir, A; Wang, X	1
Bebin, EM; Cutter, GR; Gaston, TE; Liu, Y; Szaflarski, JP	1
Deng, XQ; Song, MX	1
Mahendran, G; Vijayan, R	1
Baker, EM; George, AL; Hawkins, NA; Kearney, JA; Meisler, MH; Patel, MK; Thompson, CH; Wagnon, JL; Wengert, ER	1
Battaglia, D; Coppola, G; Curatolo, P; Cusmai, R; D'Aniello, A; Di Gennaro, G; Matricardi, S; Moavero, R; Parisi, P; Pruna, D; Spalice, A; Verrotti, A; Vigevano, F	1
Bosmans, F; Diaz-Bustamante, M; Dutton, S; Escayg, A; Gilchrist, J; Kalia, J; McPherson, A; Olivares, N	1
Ito, S; Oguni, H	1
Ohtsuka, Y	1
Accorsi, P; Balestri, P; Coppola, G; Dontin, SD; Gobbi, G; Grosso, S; Parisi, P; Pruna, D; Verrotti, A	1
Besag, F; Coppola, G; Curatolo, P; Cusmai, R; Dulac, O; Kluger, G; Moavero, R; Nabbout, R; Nikanorova, M; Pisani, F; Verrotti, A; von Stülpnagel, C	1
Bergin, AM; Bolton, J; Bourgeois, BF; Harini, C; Kadish, NE; Kapur, K; Kothare, SV; Libenson, M; Loddenkemper, T; Olson, H; Peters, J; Poduri, A; Ramgopal, S; Rotenberg, A; Sánchez Fernández, I; Takeoka, M; Thome-Souza, S	1
Alsaad, AM; Koren, G	1
Guan, LP; Quan, ZS	1
Awaya, T; Heike, T; Ide, M; Kato, T; Nakata, M; Saito, K; Yoshida, T	1
Dhanda, A; Kamboj, VK; Ranjan, S; Verma, PK	1
Cnaan, A; Dlugos, DJ; Kessler, SK; McCarthy, A	1
Ayati, A; Emami, S; Foroumadi, A	1
Arcella, A; Cantore, G; Di Gennaro, G; Esposito, V; Eusebi, F; Fredholm, BB; Fucile, S; Limatola, C; Manfredi, M; Martinello, K; Mascia, A; Miledi, R; Piccari, V; Quarato, PP; Roseti, C; Simonato, M	1
Bast, T; Boor, R; Ernst, JP; Haberlandt, E; Kluger, G; Kurlemann, G; Makowski, C; Runge, U; Schneider, F	2
Stafstrom, CE	1
Verdian, L; Yi, Y	1
Conry, J; Krauss, G; LoPresti, A; Mann, A; Narurkar, M; Wheless, JW	1
Albani, F; Baruzzi, A; Candela, C; Contin, M; Mohamed, S; Riva, R	1
Bromfield, EB; Drislane, FW; Dworetzky, BA; Farina, EL; Fowler, KM; Herzog, AG; Schomer, DL; Smithson, SD	1
Best, R; Hutchinson, DJ; Liou, Y; Zhao, F	1
Arroyo, S; Glauser, T; Kluger, G; Krauss, G; Perdomo, C; Seeruthun, R	1
Wisniewski, CS	1
Balestri, A; Coppola, G; Curatolo, P; D'Aniello, A; Fels, A; Franzoni, E; Grosso, S; Habetswallner, F; Mangano, S; Parisi, P; Pascotto, A; Spalice, A; Veggiotti, P; Verrotti, A; Zamponi, N	1
Bergin, AM; Bourgeois, BF; Duffy, FH; Eksioglu, YZ; Gooty, VD; Kothare, SV; Libenson, M; Loddenkemper, T; Poduri, A; Rotenberg, A; Takeoka, M; Vendrame, M	1
Falchi, M; Filippi, L; Guerrini, R; Innocenti, M; la Marca, G; Malvagia, S; Moneti, G; Pellacani, S; Rosati, A	1
Joseph, JR; Schultz, RJ; Wilfong, AA	1
Bergin, AM; Bourgeois, BF; Coulter, D; Duffy, FH; Kothare, SV; Libenson, MH; Loddenkemper, T; Olson, HE; Poduri, A; Rotenberg, A; Takeoka, M; Vendrame, M	1
Perucca, E; Prunetti, P	1
Ballone, E; Chiarelli, F; Curatolo, P; Loiacono, G; Mattei, PA; Verrotti, A	1
Antzelevitch, C; Borggrefe, M; Brandt, C; Ebner, A; Göksu, T; Kuschyk, J; Papavassiliu, T; Rudic, B; Schimpf, R; Veltmann, C; Wolpert, C	1
Crespel, A; Gelisse, P; Mourand, I	1
Dahlin, MG; Ohman, I	1
Kadaba, PK	1
Chimirri, A; De Sarro, A; De Sarro, G; Ferreri, G; Gitto, R; Orlando, V; Quartarone, S; Russo, E	1
Nawrot, M	1
BAJER, A; SAHANEK, O	1
Disteldorf, E; Jarry, H; Lehan, N; Mares, U; Rune, GM; von Lossow, R; Wehrenberg, U; Zhou, L	1
Anderson, GD; Cheng-Hakimian, A; Miller, JW	1
Arroyo, S	1
Chai, KY; Jin, YZ; Li, FN; Li, G; Quan, ZS; Sun, XY	1
Anderson, GD; Cheng-Hakimian, A; Hakimian, S; Miller, JW	1
Heaney, D; Walker, MC	1
Kreutzkamp, B	1
Arroyo, S; Glauser, T; Kluger, G; Krauss, G; Perdomo, C; Sachdeo, R	1
Cloyd, J; Critchley, D; Fuseau, E; Perucca, E	1
Dailey, JW; Jo, M; Jobe, PC; Ko, KH; Seo, DO; Yan, QS	1
Alif, L; Godbillon, J; Lecaillon, JB; Moes, D; Rouan, MC; Souppart, C	1
Bialer, M; Johannessen, SI; Kupferberg, HJ; Levy, RH; Loiseau, P; Perucca, E	1
Bac, P; Dupont, C; Evrard, P; Gressens, P; Maurois, P; Pages, N; Stables, JP; Vamecq, J	1
Balon, R	1
Dale, TJ; Dupere, JR; Starkey, SJ; Xie, X	1
Jain, KK	1
Canger, R; Henriksen, O; Karolchyk, MA; Pålhagen, S; Rivière, ME; van Parys, JA	1
Aldenkamp, AP	1
Meldrum, BS; Patel, S; White, HS	1
Heinemann, U; Zhang, CL	1
Ashton, D; Willems, R	1
De Beukelaar, F; Tritsmans, L	1
Czuczwar, SJ; Janusz, W; Kleinrok, Z; Szczepanik, B	1
Hulsman, J; Rentmeester, T	1
De Beukelaar, F; Overweg, J	1
Baud, J; Benedict, M; Bischoff, S; Bittiger, H; Fagg, GE; Hauser, K; Meier, R; Portet, C; Schmutz, M; Thedinga, K	1

Reviews

24 review(s) available for triazoles and Aura

Article	Year
An Important Potential Anti-Epileptic/Anticonvulsant Active Group: A Review of 1,2,4-Triazole Groups and Their Action. Drug research, 2022, Volume: 72, Issue:3 Topics: Anticonvulsants; Epilepsy; Humans; Seizures; Triazoles	2022
Recent developments on triazole nucleus in anticonvulsant compounds: a review. Journal of enzyme inhibition and medicinal chemistry, 2018, Volume: 33, Issue:1 Topics: Anticonvulsants; Epilepsy; Humans; Molecular Structure; Triazoles	2018
[Treatment of pediatric epilepsy]. Nihon rinsho. Japanese journal of clinical medicine, 2014, Volume: 72, Issue:5 Topics: Adolescent; Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dioxolanes; Drug Approval; Drug Substitution; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Levetiracetam; Patient Education as Topic; Piracetam; Practice Guidelines as Topic; Topiramate; Triazines; Triazoles; Valproic Acid	2014
[New antiepileptic drugs: characteristics and clinical applications]. Nihon rinsho. Japanese journal of clinical medicine, 2014, Volume: 72, Issue:5 Topics: Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dioxolanes; Drug Approval; Drug Interactions; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Japan; Lamotrigine; Levetiracetam; Piracetam; Safety; Topiramate; Triazines; Triazoles	2014
Current role of rufinamide in the treatment of childhood epilepsy: literature review and treatment guidelines. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2014, Volume: 18, Issue:6 Topics: Anticonvulsants; Epilepsy; Female; Guidelines as Topic; Humans; Male; Triazoles	2014
Exposure to rufinamide and risks of CNS adverse events in drug-resistant epilepsy: a meta-analysis of randomized, placebo-controlled trials. British journal of clinical pharmacology, 2014, Volume: 78, Issue:6 Topics: Anticonvulsants; Central Nervous System Diseases; Disorders of Excessive Somnolence; Dizziness; Drug Resistance; Epilepsy; Fatigue; Headache; Humans; Randomized Controlled Trials as Topic; Risk; Triazoles	2014
3,4-DHQLO and Triazole and Its Related Analogues with Anticonvulsant Effects. Mini reviews in medicinal chemistry, 2016, Volume: 16, Issue:4 Topics: Animals; Anticonvulsants; Drug Design; Epilepsy; Humans; Hydroquinones; Seizures; Structure-Activity Relationship; Triazoles	2016
1,2,4-triazole derivatives as potential scaffold for anticonvulsant activity. Central nervous system agents in medicinal chemistry, 2015, Volume: 15, Issue:1 Topics: Animals; Anticonvulsants; Epilepsy; Humans; Seizures; Structure-Activity Relationship; Triazoles	2015
The importance of triazole scaffold in the development of anticonvulsant agents. European journal of medicinal chemistry, 2016, Feb-15, Volume: 109 Topics: Animals; Anticonvulsants; Drug Discovery; Epilepsy; Humans; Triazoles	2016
Safety and tolerability of rufinamide in children with epilepsy: a pooled analysis of 7 clinical studies. Journal of child neurology, 2009, Volume: 24, Issue:12 Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Disorders of Excessive Somnolence; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Female; Headache; Humans; Male; Treatment Outcome; Triazoles; Vomiting	2009
Rufinamide: a new antiepileptic medication for the treatment of seizures associated with lennox-gastaut syndrome. The Annals of pharmacotherapy, 2010, Volume: 44, Issue:4 Topics: Aged; Anticonvulsants; Chemistry, Pharmaceutical; Child; Clinical Trials, Phase III as Topic; Counseling; Drug Resistance; Epilepsies, Partial; Epilepsy; Humans; Off-Label Use; Randomized Controlled Trials as Topic; Seizures; Syndrome; Triazoles	2010
Rufinamide for refractory epilepsy in a pediatric and young adult population. Epilepsy research, 2011, Volume: 93, Issue:1 Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Longitudinal Studies; Male; Treatment Outcome; Triazoles; Young Adult	2011
New and forthcoming anti-epileptic drugs. Current opinion in neurology, 2011, Volume: 24, Issue:2 Topics: Acetamides; Anticonvulsants; Clinical Trials as Topic; Dioxolanes; Drug Approval; Drug Discovery; Epilepsy; Humans; Lacosamide; Remission Induction; Triazoles	2011
Efficacy of rufinamide in drug-resistant epilepsy: a meta-analysis. Pediatric neurology, 2011, Volume: 44, Issue:5 Topics: Anticonvulsants; Chi-Square Distribution; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsy; Humans; Odds Ratio; Triazoles	2011
Rational drug design and the discovery of the delta2-1,2,3-triazolines, a unique class of anticonvulsant and antiischemic agents. Current medicinal chemistry, 2003, Volume: 10, Issue:20 Topics: Animals; Anticonvulsants; Brain Ischemia; Drug Design; Epilepsy; Humans; Pharmacokinetics; Stroke; Structure-Activity Relationship; Triazoles	2003
Disorders of motion and depth. Neurologic clinics, 2003, Volume: 21, Issue:3 Topics: Alzheimer Disease; Amblyopia; Antidepressive Agents; Cerebral Veins; Cues; Depth Perception; Epilepsy; Humans; Mesencephalon; Motion Perception; Occipital Lobe; Perceptual Disorders; Piperazines; Schizophrenia; Sinus Thrombosis, Intracranial; Temporal Lobe; Triazoles; Vestibular Diseases; Williams Syndrome	2003
Rufinamide: CGP 33101, E 2080, RUF 331, Xilep. Drugs in R&D, 2005, Volume: 6, Issue:4 Topics: Anticonvulsants; Clinical Trials as Topic; Drug Interactions; Drugs, Investigational; Epilepsy; Humans; Triazoles	2005
Rufinamide: Pharmacology, clinical trials, and role in clinical practice. International journal of clinical practice, 2006, Volume: 60, Issue:11 Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy; Humans; Triazoles	2006
Rufinamide. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2007, Volume: 4, Issue:1 Topics: Animals; Anticonvulsants; Brain; Clinical Trials as Topic; Epilepsy; Humans; Triazoles	2007
Rufinamide: a new anti-epileptic medication. Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:12 Topics: Adult; Animals; Anticonvulsants; Child; Drug Interactions; Epilepsy; Humans; Randomized Controlled Trials as Topic; Syndrome; Triazoles	2007
Rufinamide. Drugs of today (Barcelona, Spain : 1998), 2007, Volume: 43, Issue:7 Topics: Animals; Anticonvulsants; Drug Interactions; Epilepsy; Humans; Triazoles	2007
[Rufinamide. An orphan drug for treatment of Lennox-Gastaut syndrome]. Medizinische Monatsschrift fur Pharmazeuten, 2007, Volume: 30, Issue:10 Topics: Anticonvulsants; Child, Preschool; Drug Interactions; Epilepsy; Female; Humans; Male; Syndrome; Triazoles	2007
An assessment of rufinamide as an anti-epileptic in comparison with other drugs in clinical development. Expert opinion on investigational drugs, 2000, Volume: 9, Issue:4 Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; Humans; Triazoles	2000
Loreclezole. Epilepsy research. Supplement, 1991, Volume: 3 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drugs, Investigational; Electroencephalography; Epilepsy; Evoked Potentials; Humans; Triazoles	1991

Trials

6 trial(s) available for triazoles and Aura

Article	Year
A comparison of anastrozole and testosterone versus placebo and testosterone for treatment of sexual dysfunction in men with epilepsy and hypogonadism. Epilepsy & behavior : E&B, 2010, Volume: 17, Issue:2 Topics: Adolescent; Adult; Anastrozole; Aromatase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Humans; Hypogonadism; Injections, Intramuscular; Male; Middle Aged; Nitriles; Prospective Studies; Sexual Dysfunction, Physiological; Testosterone; Triazoles; Young Adult	2010
Adjunctive rufinamide in Lennox-Gastaut syndrome: a long-term, open-label extension study. Acta neurologica Scandinavica, 2010, Volume: 122, Issue:3 Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Epilepsy; Female; Humans; Longitudinal Studies; Male; Treatment Outcome; Triazoles; Young Adult	2010
Rufinamide in refractory childhood epileptic encephalopathies other than Lennox-Gastaut syndrome. European journal of neurology, 2011, Volume: 18, Issue:2 Topics: Adolescent; Adult; Anticonvulsants; Brain Diseases; Child; Child, Preschool; Epilepsy; Female; Humans; Male; Triazoles; Young Adult	2011
Efficacy of rufinamide in drug-resistant epilepsy: a meta-analysis. Pediatric neurology, 2011, Volume: 44, Issue:5 Topics: Anticonvulsants; Chi-Square Distribution; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsy; Humans; Odds Ratio; Triazoles	2011
Rufinamide for generalized seizures associated with Lennox-Gastaut syndrome. Neurology, 2008, May-20, Volume: 70, Issue:21 Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Epilepsy, Absence; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Humans; Male; Syndrome; Treatment Outcome; Triazoles	2008
Rufinamide: a double-blind, placebo-controlled proof of principle trial in patients with epilepsy. Epilepsy research, 2001, Volume: 43, Issue:2 Topics: Adult; Anticonvulsants; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Female; Half-Life; Humans; Incidence; Male; Middle Aged; Nervous System Diseases; Seizures; Triazoles	2001

Other Studies

53 other study(ies) available for triazoles and Aura

Article	Year
Discovery of 7-alkyloxy- [1,2,4] triazolo[1,5-a] pyrimidine derivatives as selective positive modulators of GABA Bioorganic chemistry, 2022, Volume: 119 Topics: Animals; Anticonvulsants; Cells, Cultured; Dose-Response Relationship, Drug; Drug Discovery; Electroshock; Epilepsy; Male; Mice; Mice, Inbred Strains; Molecular Structure; Neurons; Pentylenetetrazole; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Structure-Activity Relationship; Triazoles	2022
Therapeutic Drug Monitoring for Rufinamide in Japanese Patients With Epilepsy: Focus on Drug Interactions, Tolerability, and Clinical Effectiveness. Therapeutic drug monitoring, 2022, 08-01, Volume: 44, Issue:4 Topics: Anticonvulsants; Drug Interactions; Drug Monitoring; Epilepsy; Humans; Japan; Retrospective Studies; Seizures; Treatment Outcome; Triazoles	2022
A single-center SCN8A-related epilepsy cohort: clinical, genetic, and physiologic characterization. Annals of clinical and translational neurology, 2019, Volume: 6, Issue:8 Topics: Cell Culture Techniques; Child; Cohort Studies; Epilepsy; Female; HEK293 Cells; Humans; Infant; Infant, Newborn; Male; Mutation; NAV1.6 Voltage-Gated Sodium Channel; Oxcarbazepine; Pyridines; Seizures; Sodium Channels; Triazoles	2019
Rufinamide efficacy and association with phenotype and genotype in children with intractable epilepsy: A retrospective single center study. Epilepsy research, 2020, Volume: 168 Topics: Anticonvulsants; Child; Child, Preschool; Drug Resistant Epilepsy; Epilepsy; Female; Genotype; Humans; Infant; Lennox Gastaut Syndrome; Male; Phenotype; Retrospective Studies; Seizures; Triazoles	2020
Late sodium current blocker GS967 inhibits persistent currents induced by familial hemiplegic migraine type 3 mutations of the SCN1A gene. The journal of headache and pain, 2019, Nov-15, Volume: 20, Issue:1 Topics: Action Potentials; Epilepsy; HEK293 Cells; Humans; Migraine Disorders; Migraine with Aura; Mutation; NAV1.1 Voltage-Gated Sodium Channel; Neurons; Pyridines; Sodium; Triazoles	2019
Differential Inhibition of Human Nav1.2 Resurgent and Persistent Sodium Currents by Cannabidiol and GS967. International journal of molecular sciences, 2020, Apr-01, Volume: 21, Issue:7 Topics: Action Potentials; Animals; Anticonvulsants; Cannabidiol; Epilepsy; HEK293 Cells; Humans; Ion Channel Gating; Mice; Mutation; NAV1.2 Voltage-Gated Sodium Channel; Neurons; Protein Isoforms; Pyridines; Triazoles	2020
1,2,4-Triazole-based anticonvulsant agents with additional ROS scavenging activity are effective in a model of pharmacoresistant epilepsy. Journal of enzyme inhibition and medicinal chemistry, 2020, Volume: 35, Issue:1 Topics: Acetylcholinesterase; Animals; Anticonvulsants; Antioxidants; Biphenyl Compounds; Butyrylcholinesterase; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Epilepsy; Humans; Mice; Models, Molecular; Molecular Structure; Oxidative Stress; Picrates; Reactive Oxygen Species; Structure-Activity Relationship; Triazoles	2020
Rufinamide as add-on therapy in children with epileptic encephalopathies other than Lennox-Gastaut syndrome: A study of 34 patients. Epilepsy & behavior : E&B, 2020, Volume: 108 Topics: Adolescent; Anticonvulsants; Argentina; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Humans; Lennox Gastaut Syndrome; Male; Retrospective Studies; Seizures; Triazoles; Valproic Acid	2020
Relationship between saliva and plasma rufinamide concentrations in patients with epilepsy. Epilepsia, 2020, Volume: 61, Issue:7 Topics: Adolescent; Adult; Anticonvulsants; Child; Drug Monitoring; Epilepsy; Female; Humans; Male; Saliva; Triazoles; Young Adult	2020
Efficacy and Tolerability of Rufinamide in Epileptic Children Younger Than 4 Years. Journal of child neurology, 2021, Volume: 36, Issue:4 Topics: Age Factors; Anticonvulsants; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Retrospective Studies; Treatment Outcome; Triazoles	2021
Interactions between cannabidiol and commonly used antiepileptic drugs. Epilepsia, 2017, Volume: 58, Issue:9 Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Benzodiazepines; Cannabidiol; Child; Child, Preschool; Clobazam; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Fructose; Humans; Male; Middle Aged; Topiramate; Triazoles; Young Adult	2017
Neuropharmacological and molecular docking studies of xanthones from Swertia corymbosa. Journal of receptor and signal transduction research, 2018, Volume: 38, Issue:2 Topics: Animals; Anticonvulsants; Anxiety; Electroshock; Epilepsy; Isoniazid; Male; Maze Learning; Mice; Molecular Docking Simulation; Motor Activity; Neuropharmacology; Rotarod Performance Test; Seizures; Serotonin; Swertia; Triazoles; Xanthones	2018
The novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy. Epilepsia, 2018, Volume: 59, Issue:6 Topics: Action Potentials; Animals; Anticonvulsants; Brain Diseases; Disease Models, Animal; Drug Administration Schedule; Electroshock; Epilepsy; Female; Hippocampus; Humans; Male; Mice; Mice, Transgenic; Mutation; NAV1.6 Voltage-Gated Sodium Channel; Neurons; Off-Label Use; Phenytoin; Pyridines; Triazoles	2018
Rufinamide for the treatment of refractory epilepsy secondary to neuronal migration disorders. Epilepsy research, 2014, Volume: 108, Issue:3 Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Germany; Humans; Italy; Male; Malformations of Cortical Development, Group II; Prospective Studies; Treatment Outcome; Triazoles; Young Adult	2014
Nav1.1 modulation by a novel triazole compound attenuates epileptic seizures in rodents. ACS chemical biology, 2014, May-16, Volume: 9, Issue:5 Topics: Action Potentials; Animals; Anticonvulsants; Cells, Cultured; Drug Discovery; Epilepsy; Hippocampus; Humans; Male; Mice; NAV1.1 Voltage-Gated Sodium Channel; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Triazoles; Xenopus	2014
Efficacy and safety of rufinamide in children under four years of age with drug-resistant epilepsies. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2014, Volume: 18, Issue:5 Topics: Anticonvulsants; Child, Preschool; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Male; Retrospective Studies; Treatment Outcome; Triazoles	2014
Safety and retention rate of rufinamide in 300 patients: a single pediatric epilepsy center experience. Epilepsia, 2014, Volume: 55, Issue:8 Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Male; Patient Compliance; Prospective Studies; Retrospective Studies; Sleep Wake Disorders; Treatment Outcome; Triazoles; Vomiting; Young Adult	2014
A granulocytosis associated with rufinamide: A case report. Brain & development, 2015, Volume: 37, Issue:8 Topics: Agranulocytosis; Anticonvulsants; Child; Clonazepam; Epilepsy; Humans; Male; Triazoles; Valproic Acid	2015
Retention rates of rufinamide in pediatric epilepsy patients with and without Lennox-Gastaut Syndrome. Epilepsy research, 2015, Volume: 112 Topics: Adolescent; Anticonvulsants; Child; Cohort Studies; Epilepsy; Female; Humans; Kaplan-Meier Estimate; Lennox Gastaut Syndrome; Male; Treatment Outcome; Triazoles	2015
Adenosine receptor antagonists alter the stability of human epileptic GABAA receptors. Proceedings of the National Academy of Sciences of the United States of America, 2008, Sep-30, Volume: 105, Issue:39 Topics: Adenosine; Adenosine Deaminase; Adult; Animals; Anticonvulsants; Cerebral Cortex; Epilepsy; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Male; Neurons; Oocytes; Purinergic P1 Receptor Antagonists; Pyramidal Tracts; Pyrimidines; Quinazolines; Rats; Receptors, GABA-A; Triazoles; Xanthines; Xenopus	2008
Effectiveness and tolerability of rufinamide in children and adults with refractory epilepsy: first European experience. Epilepsy & behavior : E&B, 2009, Volume: 14, Issue:3 Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Drug Resistance; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Europe; Female; Humans; Infant; Male; Middle Aged; Orphan Drug Production; Retrospective Studies; Seizures; Treatment Outcome; Triazoles; Young Adult	2009
American Epilepsy Society--62nd Annual Meeting. 5-9 December 2008, Seattle, USA. IDrugs : the investigational drugs journal, 2009, Volume: 12, Issue:2 Topics: Animals; Anticonvulsants; Biomarkers; Clinical Trials as Topic; Epilepsy; Humans; Infant; Ketones; Societies, Scientific; Spasms, Infantile; Triazoles; United States	2009
Rufinamide (Banzel) for epilepsy. The Medical letter on drugs and therapeutics, 2009, Mar-09, Volume: 51, Issue:1307 Topics: Anticonvulsants; Clinical Trials as Topic; Drug Interactions; Epilepsy; Humans; Treatment Outcome; Triazoles	2009
Rufinamide: Further evaluation is needed in Lennox-Gastaut syndrome. Prescrire international, 2008, Volume: 17, Issue:96 Topics: Adult; Child; Clinical Trials as Topic; Drug Approval; Epilepsy; Europe; Humans; Orphan Drug Production; Seizures; Triazoles	2008
Cost-utility analysis of rufinamide versus topiramate and lamotrigine for the treatment of children with Lennox-Gastaut Syndrome in the United Kingdom. Seizure, 2010, Volume: 19, Issue:1 Topics: Anticonvulsants; Child; Confidence Intervals; Cost-Benefit Analysis; Drug Utilization; Epilepsy; Follow-Up Studies; Fructose; Health Status; Humans; Lamotrigine; Markov Chains; Quality of Life; Sensitivity and Specificity; Topiramate; Triazines; Triazoles; United Kingdom	2010
Simultaneous HPLC-UV analysis of rufinamide, zonisamide, lamotrigine, oxcarbazepine monohydroxy derivative and felbamate in deproteinized plasma of patients with epilepsy. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Feb-01, Volume: 878, Issue:3-4 Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Felbamate; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Triazoles; Ultraviolet Rays; Zonisamide	2010
Stability of extemporaneously prepared rufinamide oral suspensions. The Annals of pharmacotherapy, 2010, Volume: 44, Issue:3 Topics: Adult; Anticonvulsants; Child; Chromatography, High Pressure Liquid; Drug Compounding; Drug Packaging; Drug Stability; Drug Storage; Epilepsy; Humans; Pharmaceutical Vehicles; Polypropylenes; Suspensions; Time Factors; Triazoles	2010
First European long-term experience with the orphan drug rufinamide in childhood-onset refractory epilepsy. Epilepsy & behavior : E&B, 2010, Volume: 17, Issue:4 Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Child, Preschool; Epilepsy; Europe; Female; Humans; Infant; Longitudinal Studies; Male; Middle Aged; Orphan Drug Production; Product Surveillance, Postmarketing; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Triazoles; Young Adult	2010
Experience with rufinamide in a pediatric population: a single center's experience. Pediatric neurology, 2010, Volume: 43, Issue:3 Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Pediatrics; Retrospective Studies; Seizures; Treatment Outcome; Triazoles; Young Adult	2010
Rapid assay of rufinamide in dried blood spots by a new liquid chromatography-tandem mass spectrometric method. Journal of pharmaceutical and biomedical analysis, 2011, Jan-05, Volume: 54, Issue:1 Topics: Anticonvulsants; Blood Specimen Collection; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Child, Preschool; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Infant; Male; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tandem Mass Spectrometry; Triazoles	2011
Rufinamide for the treatment of epileptic spasms. Epilepsy & behavior : E&B, 2011, Volume: 20, Issue:2 Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Male; Retrospective Studies; Spasms, Infantile; Treatment Outcome; Triazoles; Young Adult	2011
Drug-induced QT-interval shortening following antiepileptic treatment with oral rufinamide. Heart rhythm, 2012, Volume: 9, Issue:5 Topics: Administration, Oral; Adult; Aged; Anticonvulsants; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Electrocardiography; Epilepsy; Female; Follow-Up Studies; Humans; Intellectual Disability; Lennox Gastaut Syndrome; Male; Middle Aged; Spasms, Infantile; Triazoles; Young Adult	2012
Dramatic weight loss with rufinamide. Epilepsia, 2013, Volume: 54, Issue:1 Topics: Adolescent; Adult; Anticonvulsants; Body Mass Index; Epilepsy; Female; Humans; Male; Triazoles; Weight Loss; Young Adult	2013
Rufinamide in children with refractory epilepsy: pharmacokinetics, efficacy, and safety. Neuropediatrics, 2012, Volume: 43, Issue:5 Topics: Adolescent; Analysis of Variance; Anticonvulsants; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Infant; Male; Retrospective Studies; Triazoles; Valproic Acid	2012
Synthesis and evaluation of pharmacological properties of novel annelated 2,3-benzodiazepine derivatives. Journal of medicinal chemistry, 2003, Aug-14, Volume: 46, Issue:17 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzodiazepines; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred DBA; Neurons; Olfactory Pathways; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Structure-Activity Relationship; Triazoles	2003
[Triazole epilepsy]. Lekarske listy, 1951, Dec-01, Volume: 6, Issue:23 Topics: Epilepsy; Humans; Triazoles	1951
Neuroprotection by estradiol: a role of aromatase against spine synapse loss after blockade of GABA(A) receptors. Experimental neurology, 2007, Volume: 203, Issue:1 Topics: Animals; Aromatase; Cells, Cultured; Dendritic Spines; Down-Regulation; Enzyme Inhibitors; Epilepsy; Estradiol; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Letrozole; Nerve Degeneration; Neural Inhibition; Neuroprotective Agents; Nitriles; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Transmission; Triazoles	2007
Synthesis of 8-alkoxy-4,5-dihydro-[1,2,4]triazole[4,3-a]quinoline-1-ones and evaluation of their anticonvulsant properties. Archives of pharmacal research, 2006, Volume: 29, Issue:12 Topics: Animals; Anticonvulsants; Convulsants; Electroshock; Epilepsy; Female; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Pentylenetetrazole; Postural Balance; Quinolones; Spectrophotometry, Infrared; Triazoles	2006
Rufinamide: clinical pharmacokinetics and concentration-response relationships in patients with epilepsy. Epilepsia, 2008, Volume: 49, Issue:7 Topics: Administration, Oral; Adolescent; Age Factors; Anticonvulsants; Body Mass Index; Child; Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Food; Half-Life; Humans; Intrinsic Factor; Kidney Diseases; Liver Diseases; Male; Metabolic Clearance Rate; Renal Dialysis; Sex Factors; Syndrome; Triazoles	2008
The anticonvulsant effect of the broad spectrum anticonvulsant loreclezole may be mediated in part by serotonin in rats: a microdialysis study. Neuroscience letters, 1994, Sep-12, Volume: 178, Issue:2 Topics: Acoustic Stimulation; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; Genetic Predisposition to Disease; Hydroxyindoleacetic Acid; Microdialysis; Rats; Rats, Sprague-Dawley; Serotonin; Triazoles	1994
Automated analysis of a novel anti-epileptic compound, CGP 33,101, and its metabolite, CGP 47,292, in body fluids by high-performance liquid chromatography and liquid-solid extraction. Journal of chromatography. B, Biomedical applications, 1995, May-19, Volume: 667, Issue:2 Topics: Anticonvulsants; Autoanalysis; Chromatography, High Pressure Liquid; Epilepsy; Humans; Hydrogen-Ion Concentration; Microchemistry; Quality Control; Sensitivity and Specificity; Solubility; Triazoles	1995
Progress report on new antiepileptic drugs: a summary of the Third Eilat Conference. Epilepsy research, 1996, Volume: 25, Issue:3 Topics: Acetamides; Animals; Anticonvulsants; Azetidines; Carbamates; Drug Evaluation, Preclinical; Drugs, Investigational; Epilepsy; Humans; Israel; Levetiracetam; Nipecotic Acids; Phenylenediamines; Piracetam; Product Surveillance, Postmarketing; Randomized Controlled Trials as Topic; Thiazoles; Tiagabine; Triazoles	1996
Magnesium deficiency-dependent audiogenic seizures (MDDASs) in adult mice: a nutritional model for discriminatory screening of anticonvulsant drugs and original assessment of neuroprotection properties. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jun-01, Volume: 18, Issue:11 Topics: Acoustic Stimulation; Animals; Anticonvulsants; Azepines; Brain Chemistry; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Epilepsy; gamma-Aminobutyric Acid; Locomotion; Magnesium Deficiency; Melatonin; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Neuroprotective Agents; Platelet Aggregation Inhibitors; Triazoles	1998
Nefazodone for mood disorder associated with epilepsy. The Journal of clinical psychiatry, 1998, Volume: 59, Issue:12 Topics: Adult; Antidepressive Agents, Second-Generation; Comorbidity; Depressive Disorder; Epilepsy; Humans; Male; Piperazines; Treatment Outcome; Triazoles	1998
The anticonvulsant BW534U87 depresses epileptiform activity in rat hippocampal slices by an adenosine-dependent mechanism and through inhibition of voltage-gated Na+ channels. British journal of pharmacology, 1999, Volume: 128, Issue:5 Topics: Action Potentials; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Anticonvulsants; Brain Chemistry; CHO Cells; Cricetinae; Electrophysiology; Enzyme Inhibitors; Epilepsy; Female; Hippocampus; In Vitro Techniques; Ion Channel Gating; Magnesium; Male; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channels; Triazoles	1999
Effects of antiepileptic drugs on cognition. Epilepsia, 2001, Volume: 42 Suppl 1 Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; Triazoles; Vigabatrin	2001
Anticonvulsant profile of MDL 27,266: an orally active, broad-spectrum anticonvulsant agent. Epilepsy research, 1992, Volume: 12, Issue:3 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electric Stimulation; Epilepsy; Female; Male; Mice; Mice, Inbred DBA; Papio; Rats; Rats, Sprague-Dawley; Triazoles	1992
Effects of the triazole derivative loreclezole (R72063) on stimulus induced ionic and field potential responses and on different patterns of epileptiform activity induced by low magnesium in rat entorhinal cortex-hippocampal slices. Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:5 Topics: Animals; Anticonvulsants; Calcium; Cerebral Cortex; Epilepsy; Evoked Potentials; Female; Hippocampus; In Vitro Techniques; Magnesium; Rats; Rats, Wistar; Triazoles	1992
In vitro studies on the broad spectrum anticonvulsant loreclezole in the hippocampus. Epilepsy research, 1992, Volume: 11, Issue:2 Topics: Animals; Anticonvulsants; Calcium; Electric Stimulation; Epilepsy; Etomidate; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium Deficiency; Pentobarbital; Phenobarbital; Triazoles	1992
Influence of CGS 15943 A (a nonxanthine adenosine antagonist) on the protection offered by a variety of antiepileptic drugs against maximal electroshock-induced seizures in mice. Journal of neural transmission. General section, 1991, Volume: 86, Issue:2 Topics: Adenosine; Animals; Anticonvulsants; Disease Susceptibility; Drug Interactions; Electroshock; Epilepsy; Male; Mice; Motor Activity; Quinazolines; Triazoles	1991
Efficacy and safety evaluation of loreclezole as add-on treatment in therapy-resistant epilepsy patients. Epilepsy research, 1991, Volume: 8, Issue:2 Topics: Adult; Anticonvulsants; Drug Resistance; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Triazoles	1991
Single-dose efficacy evaluation of loreclezole in patients with photosensitive epilepsy. Epilepsy research, 1990, Volume: 6, Issue:3 Topics: Adult; Anticonvulsants; Drug Administration Schedule; Epilepsy; Female; Humans; Male; Molecular Structure; Photic Stimulation; Triazoles	1990
CGP 31358 binds to a site on the NMDA receptor that is coupled to both the transmitter recognition site and the channel domain. Neuroscience letters, 1989, Dec-15, Volume: 107, Issue:1-3 Topics: Animals; Anticonvulsants; Binding, Competitive; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Epilepsy; Glutamates; Glutamic Acid; Mice; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Subcellular Fractions; Triazoles	1989