triazoles has been researched along with Astrocytoma, Grade IV in 34 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (5.88) | 18.2507 |
2000's | 2 (5.88) | 29.6817 |
2010's | 21 (61.76) | 24.3611 |
2020's | 9 (26.47) | 2.80 |
Authors | Studies |
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Karbe, AG; Kremenetskaia, I; Onken, JS; Prem, M; Scherschinski, L; Tinhofer, I; Vajkoczy, P | 1 |
Kumar, R; Kumar, S; Veedu, RN; Wang, T | 1 |
Kuo, YC; Lee, YJ; Rajesh, R | 1 |
Bhanja, D; Connor, J; Mansouri, A; Neighbors, J; Zadeh, G | 1 |
Bengtsson, J; Bolin, S; Čančer, M; Drews, LF; Forsberg-Nilsson, K; Nelander, S; Rosén, G; Swartling, FJ; Uhrbom, L; Weishaupt, H; Westermark, B | 1 |
Andrade, P; Campos, JM; Carvalho, I; Figueiró, F; Fraga Dias, A; Kawano, DF; Oliveira Battastini, AM; Tomich de Paula da Silva, CH; Torres, FC | 1 |
Ang, BT; Cheng, HS; Chong, YK; Law, CLD; Low, ZYJ; Marvalim, C; Tan, NS; Tang, C; Zhu, P | 1 |
Couvertier, S; Feyertag, F; Guckian, K; Huber, KVM; Johnson, DS; Martin, JG; Ward, JA; Zhang, L | 1 |
Chen, YJ; Ding, JC; Hu, GS; Hu, YH; Liu, JY; Liu, W; Xia, L; Xia, NS; Zheng, ZZ | 1 |
Abdelkafi-Koubaa, Z; Aissa, I; Assel, A; Ben Jannet, H; Chouaïb, K; Harrath, AH; Jalouli, M; Marrakchi, N; Romdhane, A | 1 |
Altieri, DC; Halatsch, ME; Ishida, CT; Karpel-Massler, G; Shu, C; Siegelin, MD; Westhoff, MA | 1 |
Bai, Y; Chen, Y; Dong, X; Han, Y; Jiang, S; Luo, SX; Wu, B; Zhang, H; Zhang, Y; Zhao, G; Zhong, S | 1 |
Fahey, JM; Girotti, AW; Smith, BC; Stancill, JS | 1 |
Alsheikh, H; Bastola, S; Chen, Z; Chhipa, R; DasGupta, B; Furuta, T; Gibson, JT; Hambardzumyan, D; Kang, KD; Kim, SH; Komarova, S; Lee, LJ; Lu, S; Lu, X; Minata, M; Nabors, B; Nakada, M; Nakano, I; Newell, EW; Norian, LA; Sabit, H; Sadahiro, H; Shi, J; Simoni, Y; Wang, J; Yamaguchi, S; Yu, H; Zhang, S | 1 |
Camphausen, K; O'Neill, JW; Rath, BH; Tofilon, PJ; Wahba, A | 1 |
Baratta, MG | 1 |
Agnihotri, S; Aldape, KD; Bunda, S; Burrell, K; Chen, EX; Jalali, S; Karimi, S; Kumar, S; Li, M; Liu, J; Mamatjan, Y; Mansouri, A; Mansouri, S; Nejad, R; Singh, O; Singh, SK; Vartanian, A; Zadeh, G | 1 |
Bianchetti, E; Ishida, CT; Karpel-Massler, G; Shang, E; Shu, C; Siegelin, MD; Westhoff, MA; Zhang, Y | 1 |
Ascari, L; Buarque, CD; Colombo, E; Cordeiro, Y; da Silva, VD; de Faria, BM; Flores, LS; Freitas, GPA; Romão, L | 1 |
Cheng, Z; Gong, Y; Knapp, S; Lu, K; Lu, X; Ma, Y; Muller, S; Pierce, LA; Thompson, RC; Wang, J | 1 |
Aibe, N; Kagiya, T; Nakamura, S; Nishimura, T; Okabe, H; Yamazaki, H; Yoshida, K | 1 |
Bradner, JE; Janardhanam, VA; Rajagopalan, V; Vaidyanathan, M | 1 |
Green, AL; Hsu, JH; Hubbell-Engler, B; Jones, K; Knoff, DS; Kung, AL; Ligon, KL; Maire, CL; McCauley, D; Perry, JA; Ramkissoon, LA; Ramkissoon, SH; Shacham, S | 1 |
Barr, CL; Cavenee, WK; Cloughesy, TF; Furnari, FB; Gahman, TC; Hon, GC; Ikegami, S; Jenkins, D; Kuan, S; Lee, AY; Li, B; Liu, F; Lucey, G; Mischel, PS; Ren, B; Shiau, AK; Turner, KM; Villa, GR; Wei, B; Yang, H; Ye, Z; Yong, WH; Zanca, C; Zhang, W | 1 |
Avril, S; Garcion, E; Guillet, C; Legendre, C | 1 |
Boyd, AW; Cryan, SA; Day, BW; Heilinger, T; Kim, EL; Lode, HN; O'Connor, G; Pokorny, JL; Prehn, JH; Ramsey, JM; Sarkaria, JN; Stringer, BW; Tivnan, A | 1 |
Abounader, R; Buchanan, S; diPierro, C; Guessous, F; Marcinkiewicz, L; Sarkaria, J; Schiff, D; Zhang, Y | 1 |
Kast, RE | 1 |
Ascierto, ML; Bradley, R; De Giorgi, V; DeKoning, T; Enter, MA; Essenburg, C; Kang, L; Kaufman, DW; Kefene, L; Koeman, J; Marincola, FM; O'Rourke, TJ; Su, Y; Vande Woude, GF; Wang, E; Worschech, A; Xie, Q | 1 |
Castonguay, A; Doucet, C; Juhas, M; Maysinger, D | 1 |
Benini, A; Borea, PA; Gessi, S; Leung, E; Maclennan, S; Merighi, S; Mirandola, P; Varani, K | 1 |
Alavi, JB; Carson, KA; Fisher, JD; Grossman, SA; Lush, R; Mikkelsen, T; Rosenfeld, S | 1 |
Jacobs, W; Kohn, EC; Mikkelsen, T; Nelson, K; Rosenblum, ML; Smith, R | 1 |
Carre, J; Eleouet, S; Heyman, D; Lajat, Y; Patrice, T; Rousset, N; Vonarx, V | 1 |
1 review(s) available for triazoles and Astrocytoma, Grade IV
Article | Year |
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Glioblastoma: synergy of growth promotion between CCL5 and NK-1R can be thwarted by blocking CCL5 with miraviroc, an FDA approved anti-HIV drug and blocking NK-1R with aprepitant, an FDA approved anti-nausea drug.
Topics: Anti-HIV Agents; Antiemetics; Antineoplastic Agents; Aprepitant; CCR5 Receptor Antagonists; Cyclohexanes; Drug Approval; Drug Interactions; Glioblastoma; Humans; Maraviroc; Mitogen-Activated Protein Kinase 3; Morpholines; Neurokinin-1 Receptor Antagonists; Phosphorylation; Signal Transduction; Triazoles; United States; United States Food and Drug Administration | 2010 |
1 trial(s) available for triazoles and Astrocytoma, Grade IV
Article | Year |
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Phase II clinical and pharmacologic study of radiation therapy and carboxyamido-triazole (CAI) in adults with newly diagnosed glioblastoma multiforme.
Topics: Administration, Oral; Adult; Aged; Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Calcium Channel Blockers; Case-Control Studies; Chemotherapy, Adjuvant; Drug Interactions; Glioblastoma; Humans; Kaplan-Meier Estimate; Middle Aged; Radiotherapy, Adjuvant; Treatment Outcome; Triazoles; United States | 2007 |
32 other study(ies) available for triazoles and Astrocytoma, Grade IV
Article | Year |
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Regulation of the Receptor Tyrosine Kinase AXL in Response to Therapy and Its Role in Therapy Resistance in Glioblastoma.
Topics: Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Combined Modality Therapy; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Signal Transduction; Temozolomide; Triazoles; Tumor Hypoxia; Up-Regulation | 2022 |
Novel 3'-[4-fluoroaryl-(1,2,3-triazol-1-yl)]-3'-deoxythymidine analogues: Design, synthesis, characterization and their potential as anticancer agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Glioblastoma; Humans; Structure-Activity Relationship; Thymidine; Triazoles | 2022 |
Enhanced activity of AZD5582 and SM-164 in rabies virus glycoprotein-lactoferrin-liposomes to downregulate inhibitors of apoptosis proteins in glioblastoma.
Topics: Alkynes; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Glioblastoma; Humans; Lactoferrin; Liposomes; Oligopeptides; Rabies virus; Triazoles | 2022 |
Neuropharmacological Study of Posaconazole for Glioblastoma: A Phase 0 Clinical Trial Protocol.
Topics: Animals; Brain Neoplasms; Dialysis Solutions; Glioblastoma; Hexokinase; Lactates; Mice; Pyruvates; Triazoles | 2022 |
BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Azepines; Brain Neoplasms; Cell Line, Tumor; Drug Synergism; Female; Glioblastoma; Humans; Male; Middle Aged; N-Myc Proto-Oncogene Protein; Proteins; Temozolomide; Triazoles | 2019 |
1,2,3-Triazole tethered 2-mercaptobenzimidazole derivatives: design, synthesis and molecular assessment toward C6 glioma cell line.
Topics: Antineoplastic Agents; Benzimidazoles; Cell Proliferation; Cell Survival; Drug Design; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Molecular Docking Simulation; Triazoles; Tumor Cells, Cultured | 2020 |
Kinomic profile in patient-derived glioma cells during hypoxia reveals c-MET-PI3K dependency for adaptation.
Topics: Animals; Antioxidants; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Hypoxia; Male; Mice; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-met; Pyrazines; Pyrrolidinones; Quinolines; Signal Transduction; Temozolomide; Transcriptome; Triazoles | 2021 |
Chemoproteomic Profiling of Covalent XPO1 Inhibitors to Assess Target Engagement and Selectivity.
Topics: Amyotrophic Lateral Sclerosis; Antineoplastic Agents; Cell Line, Tumor; Exportin 1 Protein; Glioblastoma; Humans; Hydrazines; Karyopherins; Receptors, Cytoplasmic and Nuclear; Triazoles | 2021 |
BRD4 inhibition boosts the therapeutic effects of epidermal growth factor receptor-targeted chimeric antigen receptor T cells in glioblastoma.
Topics: Animals; Azepines; Brain Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Combined Modality Therapy; Epigenesis, Genetic; ErbB Receptors; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Immunotherapy, Adoptive; Mice; Neoplasm Metastasis; Receptors, Chimeric Antigen; Transcription Factors; Triazoles; Xenograft Model Antitumor Assays | 2021 |
Glioblastoma-specific anticancer activity of newly synthetized 3,5-disubstituted isoxazole and 1,4-disubstituted triazole-linked tyrosol conjugates.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Isoxazoles; Molecular Structure; Phenylethyl Alcohol; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured | 2021 |
Mitochondrial matrix chaperone and c-myc inhibition causes enhanced lethality in glioblastoma.
Topics: Acetanilides; Animals; Azepines; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum Chaperone BiP; Glioblastoma; Guanidines; Heat-Shock Proteins; Heterocyclic Compounds, 3-Ring; Humans; Lactams, Macrocyclic; Mice, Nude; Mitochondria; Mitochondrial Proteins; Molecular Chaperones; Proto-Oncogene Proteins c-myc; RNA Interference; Triazoles; Xenograft Model Antitumor Assays | 2017 |
Identification of Driver Genes and Key Pathways of Glioblastoma Shows JNJ-7706621 as a Novel Antiglioblastoma Drug.
Topics: Adult; Apoptosis; Aurora Kinase A; Brain Neoplasms; Cell Cycle; Cell Line; Cell Line, Tumor; Cytoskeletal Proteins; Disease-Free Survival; Female; Flow Cytometry; Glioblastoma; Humans; In Vitro Techniques; Kinesins; Male; Microtubule-Associated Proteins; Molecular Targeted Therapy; Nuclear Proteins; Prognosis; Protein Interaction Maps; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Survival Rate; Transcriptome; Triazoles; Tumor Stem Cell Assay | 2018 |
Nitric oxide antagonism to glioblastoma photodynamic therapy and mitigation thereof by BET bromodomain inhibitor JQ1.
Topics: Apoptosis; Azepines; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glioblastoma; Humans; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nuclear Proteins; Photochemotherapy; Proteins; Protoporphyrins; Transcription Factors; Triazoles; Up-Regulation | 2018 |
Activation of the Receptor Tyrosine Kinase AXL Regulates the Immune Microenvironment in Glioblastoma.
Topics: Animals; Apoptosis; Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Glioblastoma; Glioma; Humans; Male; Mice; Middle Aged; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Triazoles; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2018 |
The XPO1 Inhibitor Selinexor Inhibits Translation and Enhances the Radiosensitivity of Glioblastoma Cells Grown
Topics: Animals; Brain Neoplasms; Female; Glioblastoma; Humans; Hydrazines; Mice; Mice, Nude; Radiation Tolerance; Triazoles | 2018 |
Getting to the brain.
Topics: Animals; Antineoplastic Agents; Azepines; Blood-Brain Barrier; Brain; Brain Neoplasms; Drug Carriers; Drug Delivery Systems; Glioblastoma; Humans; Mice; Nanomedicine; Polyethylene Glycols; Temozolomide; Transferrin; Triazoles | 2018 |
Ketoconazole and Posaconazole Selectively Target HK2-expressing Glioblastoma Cells.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Energy Metabolism; Gene Expression Regulation, Neoplastic; Glioblastoma; Hexokinase; Humans; Ketoconazole; Male; Mice; Triazoles; Xenograft Model Antitumor Assays | 2019 |
Dual Inhibition of Bcl-2/Bcl-xL and XPO1 is synthetically lethal in glioblastoma model systems.
Topics: Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; bcl-X Protein; Brain Neoplasms; Cell Proliferation; Drug Therapy, Combination; Exportin 1 Protein; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Hydrazines; Karyopherins; Mice; Mice, Nude; Proto-Oncogene Proteins c-bcl-2; Receptors, Cytoplasmic and Nuclear; Sulfonamides; Triazoles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2018 |
Design, synthesis, structural characterization and in vitro evaluation of new 1,4-disubstituted-1,2,3-triazole derivatives against glioblastoma cells.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Molecular Structure; Rats; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured | 2019 |
Inhibition of BET bromodomain targets genetically diverse glioblastoma.
Topics: Animals; Azepines; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Disease Progression; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioblastoma; Humans; Mice; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; RNA Interference; Signal Transduction; Transcription, Genetic; Triazoles; Xenograft Model Antitumor Assays | 2013 |
Intensity-modulated radiation therapy with hypoxic sensitizer AK-2123 (sanazole) for glioblastoma multiforme using simultaneous integrated boost technique.
Topics: Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Humans; Hypoxia; Middle Aged; Prognosis; Radiation-Sensitizing Agents; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Triazoles | 2013 |
Pre-clinical analysis of changes in intra-cellular biochemistry of glioblastoma multiforme (GBM) cells due to c-Myc silencing.
Topics: Animals; Azepines; Brain Neoplasms; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioblastoma; Glycogen; Immunohistochemistry; Lipid Metabolism; Male; Proto-Oncogene Proteins c-myc; Rats, Wistar; Survival Analysis; Triazoles | 2014 |
Preclinical antitumor efficacy of selective exportin 1 inhibitors in glioblastoma.
Topics: Acrylamides; Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Differentiation; Cell Line, Tumor; Dose-Response Relationship, Drug; Exportin 1 Protein; Glioblastoma; Humans; Hydrazines; Karyopherins; Macaca fascicularis; Male; Mice; Oxadiazoles; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Thiazoles; Treatment Outcome; Triazoles; Xenograft Model Antitumor Assays | 2015 |
EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling.
Topics: Adult; Animals; Azepines; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Child; Epigenesis, Genetic; ErbB Receptors; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Glioblastoma; Humans; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Nerve Tissue Proteins; Signal Transduction; SOX9 Transcription Factor; Transcriptome; Triazoles | 2015 |
Low oxygen tension reverses antineoplastic effect of iron chelator deferasirox in human glioblastoma cells.
Topics: Benzoates; Cell Hypoxia; Cell Line, Tumor; Combined Modality Therapy; Deferasirox; Drug Resistance, Neoplasm; Glioblastoma; Humans; Iron Chelating Agents; Oxygen; Triazoles | 2016 |
Anti-GD2-ch14.18/CHO coated nanoparticles mediate glioblastoma (GBM)-specific delivery of the aromatase inhibitor, Letrozole, reducing proliferation, migration and chemoresistance in patient-derived GBM tumor cells.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Aromatase Inhibitors; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gangliosides; Glioblastoma; HeLa Cells; Humans; Immunotoxins; Lactic Acid; Letrozole; Nanoparticles; Nitriles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Transfection; Triazoles | 2017 |
An orally bioavailable c-Met kinase inhibitor potently inhibits brain tumor malignancy and growth.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Brain Neoplasms; Flow Cytometry; Glioblastoma; Humans; Mice; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridazines; Triazoles | 2010 |
Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma.
Topics: Autocrine Communication; Biomarkers; Blotting, Western; Cell Line, Tumor; Cluster Analysis; Comparative Genomic Hybridization; DNA Primers; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Gene Expression Regulation, Neoplastic; Glioblastoma; Hepatocyte Growth Factor; Humans; In Situ Hybridization, Fluorescence; Microarray Analysis; Proto-Oncogene Proteins c-met; Pyridazines; Reverse Transcriptase Polymerase Chain Reaction; Triazoles | 2012 |
New ruthenium(II)-letrozole complexes as anticancer therapeutics.
Topics: Adenine; Adenocarcinoma; Antineoplastic Agents; Aromatase Inhibitors; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coordination Complexes; Crystallography, X-Ray; Curcumin; Drug Interactions; Drug Screening Assays, Antitumor; Female; Glioblastoma; Humans; Letrozole; Nitriles; Ruthenium; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2012 |
Adenosine modulates vascular endothelial growth factor expression via hypoxia-inducible factor-1 in human glioblastoma cells.
Topics: Adenosine; Adenosine A3 Receptor Antagonists; Blotting, Western; Cell Hypoxia; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioblastoma; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phenylurea Compounds; Receptor, Adenosine A3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Triazoles; Up-Regulation; Vascular Endothelial Growth Factor A | 2006 |
Inhibitory effects of CAI in glioblastoma growth and invasion.
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Adhesion; Cell Division; Gelatinases; Glioblastoma; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Neoplasm Invasiveness; Triazoles; Tumor Cells, Cultured | 1997 |
Protoporphyrin IX fluorescence kinetics in C6 glioblastoma cells after delta-aminolevulinic acid incubation: effect of a protoporphyrinogen oxidase inhibitor.
Topics: Aminolevulinic Acid; Animals; Enzyme Inhibitors; Fluorescence; Glioblastoma; Humans; Kinetics; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Photosensitizing Agents; Protoporphyrinogen Oxidase; Protoporphyrins; Rats; Sulfonamides; Triazoles; Tumor Cells, Cultured | 1999 |