triazoles has been researched along with Androgen-Independent Prostatic Cancer in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 21 (91.30) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Dai, T; Evers, BM; Qiu, Z; Wang, J; Wang, S; Wu, Y; Yang, X; Yu, Q | 1 |
| Chau, CH; Cordes, LM; Dahut, WL; Eisner, J; Figg, WD; Gulley, JL; Karzai, F; Madan, RA; Moore, WR; Owens, H; Peer, CJ; Schmidt, KT; Steinberg, SM | 1 |
| Aggarwal, R; Chang, E; Fong, L; Friedlander, TW; Kim, W; Lin, AM; Louttit, M; Ryan, CJ; Siegel, AP; Wei, XX; Zhang, L | 1 |
| Carlock, C; Elzey, BD; Kong, Y; Li, J; Liu, X; Liu, Z; Luo, Q; Mao, F; Wang, R | 1 |
| Ding, D; Huang, H; Jimenez, R; Jin, X; Ma, T; Wang, D; Wang, L; Wu, H; Yan, Y; Ye, Z | 1 |
| Abbey, YC; Agarwal, S; Alilin, AN; Beshiri, ML; Cawley, J; Corey, E; Fang, L; Fuller, C; Guha, R; Hoover, S; Hynes, PG; Jansson, KH; Kelly, K; Klummp-Thomas, C; Lake, R; McKnight, C; Nguyen, HM; Proia, DA; Simmons, JK; Simpson, RM; Stahl, LE; Thomas, CJ; Tice, CM; Tucker, JB; Yin, J; Zhang, X | 1 |
| Alumkal, JJ; Balter, A; Burchard, J; Chiotti, KE; Coleman, DJ; Derrick, DS; Gao, L; Heiser, LM; King, CJ; Korkola, JE; Sampson, D; Schwartzman, J; Urrutia, J | 1 |
| Alumkal, JJ; Balter, A; Burchard, J; Chiotti, KE; Coleman, DJ; Derrick, DS; Gao, L; Heiser, LM; King, CJ; Schwartzman, J; Sehrawat, A; Sun, D; Tayou, J; Urrutia, J; Xia, Z | 1 |
| Baskin-Bey, E; Brown, VV; Eisner, JR; Figg, WD; Kindrick, JD; Madan, R; Peer, CJ; Schmidt, KT | 1 |
| Alumkal, J; Bottomly, D; Coleman, I; Gao, L; Gibbs, A; Kleinschmidt, R; Lisac, R; McWeeney, S; Nelson, P; Schwartzman, J; Wilmot, B | 1 |
| Asangani, IA; Cao, X; Chinnaiyan, AM; Cieslik, M; Dhanireddy, S; Dommeti, VL; Engelke, C; Escara-Wilke, J; Feng, FY; Iyer, MK; Jing, X; Malik, R; Qin, ZS; Wang, S; Wang, X; Wilder-Romans, K; Wu, YM; Yang, R | 1 |
| Phillips, R | 1 |
| Seton-Rogers, S | 1 |
| Asangani, IA; Chinnaiyan, AM | 1 |
| Adomat, H; Gleave, ME; Guns, ES; Kim, S; Mangalji, A; Moore, W; Pham, S; Toren, PJ; Zoubeidi, A | 1 |
| Figg, WD; Lochrin, SE; Price, DK | 1 |
| Bradner, JE; Chan, SC; Dehm, SM; Li, Y; Miao, L; Nyquist, MD; Raj, GV; Selth, LA; Tilley, WD | 1 |
| Bambury, RM; Rathkopf, DE | 1 |
| Antonarakis, ES; Dzinic, SH; Freeman, S; Heath, EI; Heilbrun, LK; Li, X; Liu, G; Sheng, S; Smith, D; Stein, M; Thakur, MK; Vaishampayan, U | 1 |
| Apel, IJ; Asangani, IA; Chinnaiyan, AM; Dommeti, VL; Escara-Wilke, J; Feng, FY; Krishnamurthy, PM; Navone, NM; Plymate, SR; Wang, S; Wilder-Romans, K | 1 |
| Blee, AM; Huang, H; Liu, S; Wang, L | 1 |
| Araujo, JC; Efstathiou, E; Gyftaki, R; Li-Ning-Tapia, EM; Logothetis, CJ; Lu, JF; Maity, SN; Ramachandran, S; Titus, MA; Wu, G | 1 |
| Chan, ML; Chan, SH; Chang, WL; Chou, YL; Guh, JH; Hou, DR; Hsu, JL; Hsu, LC; Leu, WJ; Liu, SP; Swain, ShP; Yu, CC | 1 |
2 review(s) available for triazoles and Androgen-Independent Prostatic Cancer
| Article | Year |
|---|---|
BET bromodomain inhibitors--a novel epigenetic approach in castration-resistant prostate cancer.
Topics: Animals; Antineoplastic Agents; Azepines; Benzodiazepines; Cell Cycle Proteins; Epigenesis, Genetic; Humans; Male; Nuclear Proteins; Prostatic Neoplasms, Castration-Resistant; Transcription Factors; Triazoles | 2014 |
Novel and next-generation androgen receptor-directed therapies for prostate cancer: Beyond abiraterone and enzalutamide.
Topics: Androgen Receptor Antagonists; Androstadienes; Androstenes; Benzamides; Benzimidazoles; Humans; Male; Naphthalenes; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Pyrazoles; Receptors, Androgen; Thiohydantoins; Triazoles | 2016 |
3 trial(s) available for triazoles and Androgen-Independent Prostatic Cancer
| Article | Year |
|---|---|
Phase 2 Study of Seviteronel (INO-464) in Patients With Metastatic Castration-Resistant Prostate Cancer After Enzalutamide Treatment.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Drug Resistance, Neoplasm; Follow-Up Studies; Humans; Male; Middle Aged; Naphthalenes; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Survival Rate; Triazoles | 2020 |
A Phase II Trial of Selinexor, an Oral Selective Inhibitor of Nuclear Export Compound, in Abiraterone- and/or Enzalutamide-Refractory Metastatic Castration-Resistant Prostate Cancer.
Topics: Aged; Androstenes; Benzamides; Humans; Hydrazines; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Triazoles | 2018 |
A phase II trial of ganetespib, a heat shock protein 90 Hsp90) inhibitor, in patients with docetaxel-pretreated metastatic castrate-resistant prostate cancer (CRPC)-a prostate cancer clinical trials consortium (PCCTC) study.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Disease-Free Survival; Docetaxel; HSP90 Heat-Shock Proteins; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Outcome; Triazoles | 2016 |
18 other study(ies) available for triazoles and Androgen-Independent Prostatic Cancer
| Article | Year |
|---|---|
The combined effect of epigenetic inhibitors for LSD1 and BRD4 alters prostate cancer growth and invasion.
Topics: Animals; Apoptosis; Azepines; Cell Cycle Proteins; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Demethylases; Humans; Male; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Transcription Factors; Triazoles | 2020 |
Plk1 Inhibition Enhances the Efficacy of BET Epigenetic Reader Blockade in Castration-Resistant Prostate Cancer.
Topics: Animals; Azepines; beta Catenin; Cell Cycle Proteins; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Nuclear Proteins; Polo-Like Kinase 1; Prostatic Neoplasms, Castration-Resistant; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Receptors, Androgen; Signal Transduction; Thiophenes; Transcription Factors; Triazoles; Xenograft Model Antitumor Assays | 2018 |
DUB3 Promotes BET Inhibitor Resistance and Cancer Progression by Deubiquitinating BRD4.
Topics: Animals; Antineoplastic Agents; Azepines; Cell Cycle Proteins; Cell Line, Tumor; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Disease Progression; Drug Resistance, Neoplasm; Endopeptidases; Gene Expression Regulation, Neoplastic; Histone Deacetylases; Humans; Male; Mice; Nuclear Proteins; Nuclear Receptor Co-Repressor 2; Piperazines; Prostate; Prostatic Neoplasms, Castration-Resistant; Protein Kinase Inhibitors; Proteolysis; Pyridines; Signal Transduction; Transcription Factors; Transcription, Genetic; Triazoles; Xenograft Model Antitumor Assays | 2018 |
High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer.
Topics: Androgen Receptor Antagonists; Animals; Antineoplastic Agents; Apoptosis; Benzamides; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Genotype; High-Throughput Screening Assays; HSP90 Heat-Shock Proteins; Humans; Isoindoles; Male; Mice; Phenotype; Phosphatidylinositol 3-Kinases; Prostate; Prostatic Neoplasms, Castration-Resistant; PTEN Phosphohydrolase; Signal Transduction; TOR Serine-Threonine Kinases; Triazoles; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2018 |
Maintenance of MYC expression promotes de novo resistance to BET bromodomain inhibition in castration-resistant prostate cancer.
Topics: Antineoplastic Agents; Azepines; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-myc; Receptors, Androgen; Triazoles | 2019 |
BET bromodomain inhibition blocks the function of a critical AR-independent master regulator network in lethal prostate cancer.
Topics: Animals; Azepines; Benzamides; Cell Cycle Proteins; Cell Line, Tumor; Chromosomal Proteins, Non-Histone; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, SCID; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Protein Biosynthesis; Receptors, Androgen; Transcription Factors; Transcription, Genetic; Triazoles | 2019 |
A population pharmacokinetic analysis of the oral CYP17 lyase and androgen receptor inhibitor seviteronel in patients with advanced/metastatic castration-resistant prostate cancer or breast cancer.
Topics: Androgen Receptor Antagonists; Antineoplastic Agents; Biological Availability; Breast Neoplasms; Clinical Trials, Phase II as Topic; Dexamethasone; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Male; Naphthalenes; Neoplasm Staging; Prostatic Neoplasms, Castration-Resistant; Steroid 17-alpha-Hydroxylase; Triazoles | 2019 |
Androgen receptor promotes ligand-independent prostate cancer progression through c-Myc upregulation.
Topics: Androgens; Azepines; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Ligands; Male; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-myc; Receptors, Androgen; Triazoles; Up-Regulation | 2013 |
Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer.
Topics: Androgen Antagonists; Androgens; Animals; Azepines; Cell Cycle Proteins; Cell Line, Tumor; Disease Models, Animal; Epigenesis, Genetic; Humans; Male; Mice; Nuclear Proteins; Oncogene Proteins, Fusion; Prostatic Neoplasms, Castration-Resistant; Protein Structure, Tertiary; Receptors, Androgen; Signal Transduction; Transcription Factors; Triazoles | 2014 |
Prostate cancer: novel targeting of androgen signalling in CRPC.
Topics: Animals; Azepines; Humans; Male; Nuclear Proteins; Prostatic Neoplasms, Castration-Resistant; Transcription Factors; Triazoles | 2014 |
Prostate cancer: BETting on epigenetic therapy.
Topics: Animals; Azepines; Cell Cycle Proteins; Humans; Male; Nuclear Proteins; Prostatic Neoplasms, Castration-Resistant; Transcription Factors; Triazoles | 2014 |
BETting on a new prostate cancer treatment.
Topics: Animals; Azepines; Humans; Male; Nuclear Proteins; Prostatic Neoplasms, Castration-Resistant; Transcription Factors; Triazoles | 2014 |
Anticancer activity of a novel selective CYP17A1 inhibitor in preclinical models of castrate-resistant prostate cancer.
Topics: Androstenes; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Naphthalenes; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Signal Transduction; Steroid 17-alpha-Hydroxylase; Triazoles; Xenograft Model Antitumor Assays | 2015 |
Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies.
Topics: Animals; Antineoplastic Agents; Azepines; Benzamides; Cell Line; Cell Line, Tumor; Chromatin; Dimerization; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Male; Mice, Nude; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Response Elements; Transcriptional Activation; Triazoles | 2015 |
BET Bromodomain Inhibitors Enhance Efficacy and Disrupt Resistance to AR Antagonists in the Treatment of Prostate Cancer.
Topics: Acetanilides; Androgen Receptor Antagonists; Animals; Antineoplastic Combined Chemotherapy Protocols; Azepines; Benzamides; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Heterocyclic Compounds, 3-Ring; Humans; Male; Mice; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Signal Transduction; Triazoles; Xenograft Model Antitumor Assays | 2016 |
BET bromodomain-mediated interaction between ERG and BRD4 promotes prostate cancer cell invasion.
Topics: Azepines; Base Sequence; Benzodiazepines; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; HEK293 Cells; Humans; Male; Neoplasm Invasiveness; Nuclear Proteins; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Proteins; Transcription Factors; Transcriptional Regulator ERG; Triazoles | 2016 |
Targeting of CYP17A1 Lyase by VT-464 Inhibits Adrenal and Intratumoral Androgen Biosynthesis and Tumor Growth of Castration Resistant Prostate Cancer.
Topics: Abiraterone Acetate; Androgens; Animals; Biopsy; Cell Line, Tumor; Dehydroepiandrosterone; Humans; Hydrocortisone; Male; Mass Spectrometry; Mice; Mice, SCID; Naphthalenes; Neoplasm Transplantation; Precision Medicine; Prednisone; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Signal Transduction; Steroid 17-alpha-Hydroxylase; Triazoles | 2016 |
Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: the role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Fingolimod Hydrochloride; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Signal Transduction; Small Molecule Libraries; TOR Serine-Threonine Kinases; Triazoles; Xenograft Model Antitumor Assays | 2016 |