Page last updated: 2024-08-24

triazoles and Aging

triazoles has been researched along with Aging in 65 studies

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-19908 (12.31)18.7374
1990's10 (15.38)18.2507
2000's24 (36.92)29.6817
2010's21 (32.31)24.3611
2020's2 (3.08)2.80

Authors

AuthorsStudies
Conde, SV; Gonzalez, C; Martins, FO; Melo, BF; Monteiro, EC; Olea, E; Prieto-Lloret, J; Ribeiro, MJ; Sacramento, JF1
Bodduluri, S; Lyv, X; Rowe, SM; Sanders, YY; Stanford, D; Thannickal, VJ; Xiang, Z; Zhou, QJ1
Ali, EA; Ansari, M; Deldar, H; Najafi, M; Towhidi, A; Zaghari, M; Zhandi, M1
Adeldust, H; Farshad, A; Farzinpour, A; Lopez-Bejar, M; Rostamzadeh, J1
Abdo, M; Fekry, E; Makary, S1
Ahn, JH; Chen, BH; Hwang, IK; Kang, IJ; Kim, DW; Kim, H; Kim, YM; Lee, CH; Lee, JC; Lee, TK; Park, JH; Song, M; Won, MH; Yan, BC1
How, CM; Li, SW; Liao, VH1
Bajnok, A; Orbán, C; Sava, F; Toldi, G; Vásárhelyi, Z1
Chen, X; Ge, RS; Huang, T; Li, X; Lin, Z; Wang, S; Wang, Y; Zhu, Q1
de Carvalho Macedo Silva, R; de Mattos, IM; Dvylyuk, I; Epp, T; Folkes, CDA; Klein, CD; Kozii, IV; Moshynskyy, I; Simko, E; Wood, SC1
Chen, F; Ding, Y; Huang, Y; Ju, Z; Lee, W; Li, G; Li, Y; Liu, J; So, KK; Sun, H; Wang, H; Yuan, J; Zhou, J1
Ammirabile, M; Casale, M; Cinque, P; Costantini, S; Di Matola, T; Filosa, A; Prossomariti, L; Ricchi, P; Spasiano, A1
Grauer, SM; Hodgson, R; Hyde, LA1
Biedenbach, JM; Chappell, P; Gust, KA; Lotufo, GR; Stanley, JK1
Anand, S; Banerjee, P; Bir, A; Chakrabarti, S; Sahoo, A1
Basaria, S; Carlson, O; Chia, CW; Dias, JP; Egan, JM; Ferrucci, L; Melvin, D; Shardell, MD; Simonsick, EM1
Aarnoutse, RE; Blijlevens, NM; Brüggemann, RJ; Burger, DM; Donnelly, JP; Mouton, JW; Verweij, PE; Warris, A1
Kaufman, JM; Lapauw, B; Mahmoud, A; Ruige, JB; T'Sjoen, G1
Cohen, P1
Dix, DJ; Goetz, AK1
Burnett-Bowie, SA; Leder, BZ; Lee, H; McKay, EA1
Annaert, PP; Augustijns, P; Benjamin, DK; Ibrahim, JG; Thakker, DR; Yanni, SB1
Arvapalli, RK; Blough, ER; Gadde, MK; Kakarla, SK; Katta, A; Laurino, JP; Paturi, S; Rice, KM; Walker, EM; Wehner, P; Wu, M1
Brandão, R; Jesse, CR; Leite, MR; Nogueira, CW; Wilhelm, EA1
Couto, GK; Crajoinas, RO; Davel, AP; Girardi, AC; Lessa, LM; Pacheco, BP; Rossoni, LV1
Bourdel-Marchasson, I; Dejager, S; Schweizer, A1
Baker, R; Davis, DD; Fan, F; Lima, R; Moulana, M; Reckelhoff, JF; Roman, RJ; Romero, DG; Ryan, MJ; Yanes, LL; Yuan, K; Zhang, H1
Agostinho, PM; Canas, PM; Costenla, AR; Cunha, RA; de Mendonça, A; Diógenes, MJ; Maroco, J; Nogueira, C; Ribeiro, JA; Rodrigues, RJ1
Balboa, J; Freire-Garabal, M; Núñez, LA; Núñez, MJ; Rey-Méndez, M; Rivas, M; Riveiro, P; Suárez, J1
Cunha, RA; de Mendonca, A; Oliveira, CR; Rebola, N; Ribeiro, JA; Sebastião, AM1
Bagby, RM; Grigoriadis, S; Kennedy, SH1
SUGIURA, K1
Gallo, J; Leder, BZ; Longcope, C; Rohrer, JL; Rubin, SD1
Adamson, P; Arguedas, AG; Arrieta, AC; Blumer, J; Driscoll, T; Karlsson, MO; Lutsar, I; Milligan, P; Saez-Llorens, X; Vora, AJ; Walsh, TJ; Wood, N1
Alfaro, TM; Cunha, RA; Oliveira, CR; Vigia, E1
Ahmed, S; Amory, JK; Bremner, W; Cherrier, MM; Craft, S; Johnson, M; Matsumoto, AM; Peskind, ER; Raskind, MA1
Cassidy, EL; Lauderdale, S; Sheikh, JI1
Crabbe, P; De Bacquer, D; Delva, H; Giagulli, VA; Kaufman, JM; T'Sjoen, GG1
Cespuglio, R; Clément, P; Gharib, A; Sarda, N1
Huxley, VH; Wang, J1
At-Taras, E; Berger, T; Pearl, CA; Ramesh, R; Roser, JF1
Beer, B; Lippa, AS; Meyerson, LR1
van Laar, MW; van Willigenburg, AP; Volkerts, ER1
Bouillon, R; De Coster, R; Van Herck, E; Vanderschueren, D1
Dobson, JG; Fenton, RA; Sawmiller, DR1
Barbhaiya, RH; Buch, AB; Greene, DS1
Bouillon, R; De Coster, R; Ederveen, AG; Nijs, J; van Herck, E; Vanderschueren, D1
Goldberg, RJ1
Flanagan, AM; Lea, CK1
Ferré, S; Fuxe, K; Pèzzola, A; Popoli, P; Reggio, R1
Cunha, RA; Lopes, LV; Ribeiro, JA2
Cunha, RA; Pereira, MF; Ribeiro, JA1
Bianchi, L; Corsi, C; Melani, A; Pedata, F1
Boonen, S; Bouillon, R; de Coster, R; Ederveen, AG; Moermans, K; Van Herck, E; Vandenput, L; Vanderschueren, D; Verstuyf, A1
Birk, KL; Gagliano, KD; Goldberg, MR; Musson, DG; Panebianco, DL; Rogers, JD1
Eckerskorn, C; Kayser, H; Waditschatka, R; Winter, J1
Davydov, VV; Shvets, VN1
Calandra, JC; Keplinger, ML; Lyman, FL1
Prasad, RS; Vijayan, E1
Costarides, A; Csukas, S; Green, K; Riley, MV1
Birnbaum, D; Costarides, A; Csukas, S; Forbes, E; Green, K2
Baird, MB; Samis, HV1

Reviews

4 review(s) available for triazoles and Aging

ArticleYear
Therapeutic drug monitoring of voriconazole.
    Therapeutic drug monitoring, 2008, Volume: 30, Issue:4

    Topics: Aging; Antifungal Agents; Drug Interactions; Drug Monitoring; Female; Genotype; Humans; Liver Failure; Male; Pyrimidines; Renal Insufficiency; Sex Characteristics; Triazoles; Voriconazole

2008
Incretin therapies in the management of elderly patients with type 2 diabetes mellitus.
    Hospital practice (1995), 2011, Volume: 39, Issue:1

    Topics: Adamantane; Age Factors; Aged; Aging; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Exenatide; Female; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Incretins; Linagliptin; Liraglutide; Male; Middle Aged; Nitriles; Peptides; Piperidines; Purines; Pyrazines; Pyrrolidines; Quinazolines; Sitagliptin Phosphate; Treatment Outcome; Triazoles; Uracil; Venoms; Vildagliptin

2011
Molecular substrates of anxiety: clues from the heterogeneity of benzodiazepine receptors.
    Life sciences, 1982, Oct-04, Volume: 31, Issue:14

    Topics: Aging; Animals; Anxiety; Benzodiazepines; Binding, Competitive; Brain; Carbolines; Chemical Phenomena; Chemistry, Physical; Flunitrazepam; Humans; Muscles; Pentylenetetrazole; Pyridazines; Receptors, Drug; Receptors, GABA-A; Tissue Distribution; Triazoles

1982
Antidepressant use in the elderly. Current status of nefazodone, venlafaxine and moclobemide.
    Drugs & aging, 1997, Volume: 11, Issue:2

    Topics: Aged; Aging; Antidepressive Agents; Benzamides; Cyclohexanols; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Enzyme Inhibitors; Humans; Moclobemide; Monoamine Oxidase Inhibitors; Piperazines; Selective Serotonin Reuptake Inhibitors; Triazoles; Venlafaxine Hydrochloride

1997

Trials

12 trial(s) available for triazoles and Aging

ArticleYear
Effects of aromatase inhibition vs. testosterone in older men with low testosterone: randomized-controlled trial.
    Andrology, 2016, Volume: 4, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Anastrozole; Aromatase; Aromatase Inhibitors; Body Composition; Bone and Bones; Bone Density; Double-Blind Method; Estradiol; Humans; Male; Nitriles; Placebos; Testosterone; Triazoles

2016
Short-term aromatase inhibition: effects on glucose metabolism and serum leptin levels in young and elderly men.
    European journal of endocrinology, 2009, Volume: 160, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Aromatase; Aromatase Inhibitors; Blood Glucose; Cross-Over Studies; Estradiol; Humans; Insulin; Insulin-Like Growth Factor I; Leptin; Letrozole; Luteinizing Hormone; Male; Nitriles; Placebos; Testosterone; Triazoles; Young Adult

2009
Effects of aromatase inhibition on bone mineral density and bone turnover in older men with low testosterone levels.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:12

    Topics: Aged; Aging; Anastrozole; Aromatase Inhibitors; Biomarkers; Bone and Bones; Bone Density; Double-Blind Method; Endpoint Determination; Enzyme-Linked Immunosorbent Assay; Hormones; Humans; Male; Middle Aged; Nitriles; Patient Compliance; Steroids; Testis; Testosterone; Triazoles

2009
A comparison of antidepressant response in younger and older women.
    Journal of clinical psychopharmacology, 2003, Volume: 23, Issue:4

    Topics: Adult; Aged; Aging; Antidepressive Agents; Antidepressive Agents, Second-Generation; Depressive Disorder; Female; Humans; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Sertraline; Sex Characteristics; Triazoles

2003
Effects of aromatase inhibition in elderly men with low or borderline-low serum testosterone levels.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:3

    Topics: Aged; Aging; Anastrozole; Aromatase Inhibitors; Enzyme Inhibitors; Estrogens; Humans; Hypogonadism; Male; Middle Aged; Nitriles; Quality of Life; Testosterone; Treatment Outcome; Triazoles

2004
Pharmacokinetics and safety of intravenous voriconazole in children after single- or multiple-dose administration.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:6

    Topics: Aging; Alleles; Antifungal Agents; Body Weight; Child; Child, Preschool; Cohort Studies; Female; Genotype; Humans; Immunocompromised Host; Injections, Intravenous; Liver Function Tests; Male; Models, Biological; Pyrimidines; Triazoles; Voriconazole

2004
The role of aromatization in testosterone supplementation: effects on cognition in older men.
    Neurology, 2005, Jan-25, Volume: 64, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Anastrozole; Aromatase; Aromatase Inhibitors; Double-Blind Method; Estradiol; Humans; Male; Memory; Memory Disorders; Middle Aged; Neuropsychological Tests; Nitriles; Prostate-Specific Antigen; Spatial Behavior; Testosterone; Triazoles; Verbal Learning

2005
Mixed anxiety and depression in older adults: clinical characteristics and management.
    Journal of geriatric psychiatry and neurology, 2005, Volume: 18, Issue:2

    Topics: Aged; Aging; Antidepressive Agents, Second-Generation; Anxiety Disorders; Comorbidity; Depressive Disorder, Major; Female; Humans; Male; Piperazines; Psychiatric Status Rating Scales; Treatment Outcome; Triazoles

2005
Comparative assessment in young and elderly men of the gonadotropin response to aromatase inhibition.
    The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aromatase Inhibitors; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Estradiol; Feedback, Physiological; Gonadotropins; Humans; Letrozole; Male; Nitriles; Triazoles

2005
Acute and subchronic effects of nefazodone and imipramine on highway driving, cognitive functions, and daytime sleepiness in healthy adult and elderly subjects.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:1

    Topics: Adult; Aged; Aging; Antidepressive Agents; Automobile Driving; Cognition; Double-Blind Method; Humans; Imipramine; Multivariate Analysis; Piperazines; Psychomotor Performance; Reaction Time; Reference Values; Sleep; Triazoles

1995
A study of the effect of age and gender on the pharmacokinetics of nefazodone after single and multiple doses.
    Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aged; Aging; Antidepressive Agents, Second-Generation; Biotransformation; Female; Half-Life; Humans; Male; Middle Aged; Piperazines; Sex Characteristics; Triazoles

1996
Pharmacokinetics of rizatriptan in healthy elderly subjects.
    International journal of clinical pharmacology and therapeutics, 2001, Volume: 39, Issue:10

    Topics: Adult; Aged; Aging; Analysis of Variance; Area Under Curve; Chromatography, High Pressure Liquid; Double-Blind Method; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Serotonin Receptor Agonists; Triazoles; Tryptamines

2001

Other Studies

49 other study(ies) available for triazoles and Aging

ArticleYear
Contribution of adenosine and ATP to the carotid body chemosensory activity in ageing.
    The Journal of physiology, 2019, Volume: 597, Issue:19

    Topics: Adenosine; Adenosine Triphosphate; Aging; Animals; Antinematodal Agents; Carotid Body; Chemoreceptor Cells; Female; Gene Expression Regulation; Male; Rats; Rats, Wistar; Suramin; Triazines; Triazoles

2019
Brd4-p300 inhibition downregulates Nox4 and accelerates lung fibrosis resolution in aged mice.
    JCI insight, 2020, 07-23, Volume: 5, Issue:14

    Topics: Acetanilides; Aging; Animals; Azepines; Disease Models, Animal; Gene Expression Regulation; Heterocyclic Compounds, 3-Ring; Histones; Humans; Lung; Mice; NADPH Oxidase 4; Nuclear Proteins; p300-CBP Transcription Factors; Pulmonary Fibrosis; Transcription Factors; Transforming Growth Factor beta1; Triazoles

2020
Letrozole, an aromatase inhibitor, reduces post-peak age-related regression of rooster reproductive performance.
    Animal reproduction science, 2017, Volume: 183

    Topics: Aging; Animals; Chickens; Infertility, Male; Insemination, Artificial; Letrozole; Lipid Peroxidation; Male; Nitriles; Triazoles

2017
Increased sperm cell production in ageing roosters by an oral treatment with an aromatase inhibitor and a natural herbal extract designed for improving fertility.
    Reproduction in domestic animals = Zuchthygiene, 2017, Volume: 52 Suppl 4

    Topics: Administration, Oral; Aging; Animals; Aromatase Inhibitors; Chickens; Epididymis; Infertility, Male; Letrozole; Male; Nitriles; Organ Size; Phytotherapy; Plant Extracts; Seminiferous Tubules; Spermatids; Spermatogenesis; Testis; Triazoles

2017
Oxidative stress burden inhibits spermatogenesis in adult male rats: testosterone protective effect.
    Canadian journal of physiology and pharmacology, 2018, Volume: 96, Issue:4

    Topics: Aging; Animals; Biomarkers; Body Weight; Estradiol; Follicle Stimulating Hormone; Grape Seed Extract; Inflammation; Letrozole; Male; Methotrexate; Nitriles; Organ Size; Oxidative Stress; Protective Agents; Rats, Sprague-Dawley; Seminiferous Tubules; Sperm Count; Sperm Motility; Spermatogenesis; Testosterone; Triazoles

2018
Rufinamide, an antiepileptic drug, improves cognition and increases neurogenesis in the aged gerbil hippocampal dentate gyrus via increasing expressions of IGF-1, IGF-1R and p-CREB.
    Chemico-biological interactions, 2018, Apr-25, Volume: 286

    Topics: Aging; Animals; Anticonvulsants; Body Weight; Brain-Derived Neurotrophic Factor; Cognition; CREB-Binding Protein; Dentate Gyrus; Gene Expression Regulation; Gerbillinae; Insulin-Like Growth Factor I; Ki-67 Antigen; Male; Microscopy, Fluorescence; Neurogenesis; Receptor, IGF Type 1; Receptor, trkB; Triazoles

2018
Chronic exposure to triadimenol at environmentally relevant concentration adversely affects aging biomarkers in Caenorhabditis elegans associated with insulin/IGF-1 signaling pathway.
    The Science of the total environment, 2018, Nov-01, Volume: 640-641

    Topics: Aging; Animals; Biomarkers; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Fungicides, Industrial; Hydrogen Peroxide; Insulin; Insulin-Like Growth Factor I; Longevity; Proto-Oncogene Proteins c-akt; Toxicity Tests, Chronic; Triazoles

2018
Effects of caffeine and phosphodiesterase inhibitors on activation of neonatal T lymphocytes.
    Immunobiology, 2018, Volume: 223, Issue:11

    Topics: Adenosine A2 Receptor Antagonists; Adult; Aging; Caffeine; Calcium Signaling; Cells, Cultured; Cyclic AMP; Cytokines; Female; Humans; Infant, Newborn; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Milrinone; Phosphodiesterase Inhibitors; Reactive Oxygen Species; Sildenafil Citrate; T-Lymphocytes; Triazines; Triazoles

2018
Pubertal exposure to tebuconazole increases testosterone production via inhibiting testicular aromatase activity in rats.
    Chemosphere, 2019, Volume: 230

    Topics: Aging; Animals; Aromatase; Cell Differentiation; Follicle Stimulating Hormone; Fungicides, Industrial; Gene Expression; Leydig Cells; Luteinizing Hormone; Male; Rats; Rats, Sprague-Dawley; Testis; Testosterone; Triazoles; Up-Regulation

2019
Effects of chronic dietary thiamethoxam and prothioconazole exposure on Apis mellifera worker adults and brood.
    Pest management science, 2020, Volume: 76, Issue:1

    Topics: Aging; Animals; Bees; Neonicotinoids; Thiamethoxam; Triazoles

2020
Elevated H3K27ac in aged skeletal muscle leads to increase in extracellular matrix and fibrogenic conversion of muscle satellite cells.
    Aging cell, 2019, Volume: 18, Issue:5

    Topics: Acetylation; Aging; Animals; Azepines; Cell Differentiation; Cell Line; Cellular Senescence; Epigenesis, Genetic; Extracellular Matrix; Fibroblasts; Histones; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Satellite Cells, Skeletal Muscle; Triazoles

2019
Nephrolithiasis in patients exposed to deferasirox and desferioxamine: probably an age-linked event with different effects on some renal parameters.
    Annals of hematology, 2014, Volume: 93, Issue:3

    Topics: Adult; Aging; Benzoates; beta-Thalassemia; Chelation Therapy; Deferasirox; Deferoxamine; Disease Susceptibility; Female; Glomerular Filtration Rate; Humans; Hyperuricemia; Incidence; Iron Chelating Agents; Iron Overload; Italy; Kidney; Male; Nephrolithiasis; Retrospective Studies; Transfusion Reaction; Triazoles; Ultrasonography

2014
MitoPark mice, an animal model of Parkinson's disease, show enhanced prepulse inhibition of acoustic startle and no loss of gating in response to the adenosine A(2A) antagonist SCH 412348.
    Psychopharmacology, 2014, Volume: 231, Issue:7

    Topics: Adenosine A2 Receptor Antagonists; Aging; Animals; Apomorphine; Benzothiazoles; Disease Models, Animal; Dopamine Agonists; Male; Mice; Mice, Transgenic; Motor Activity; Parkinson Disease; Pramipexole; Prepulse Inhibition; Pyrimidines; Triazoles

2014
Toxicity of the conventional energetics TNT and RDX relative to new insensitive munitions constituents DNAN and NTO in Rana pipiens tadpoles.
    Environmental toxicology and chemistry, 2015, Volume: 34, Issue:4

    Topics: Aging; Animals; Anisoles; Body Burden; Explosive Agents; Larva; Lethal Dose 50; Nitro Compounds; No-Observed-Adverse-Effect Level; Rana pipiens; Swimming; Triazines; Triazoles; Trinitrotoluene

2015
The Oral Iron Chelator, Deferasirox, Reverses the Age-Dependent Alterations in Iron and Amyloid-β Homeostasis in Rat Brain: Implications in the Therapy of Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2016, Volume: 49, Issue:3

    Topics: Administration, Oral; Aging; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Benzoates; Brain; Deferasirox; Ferritins; Gene Expression Regulation; Iron; Iron Chelating Agents; Neprilysin; NF-kappa B; Oxidative Stress; Peptide Fragments; Protein Carbonylation; Rats; Rats, Wistar; Receptors, Transferrin; Spectrophotometry; Triazoles

2016
Aromatase inhibition in hypogonadal older men.
    Clinical endocrinology, 2009, Volume: 71, Issue:6

    Topics: Aged; Aging; Aromatase Inhibitors; Biomarkers; Bone and Bones; Bone Density; Humans; Hypogonadism; Male; Middle Aged; Steroids; Testis; Testosterone; Triazoles

2009
Mode of action for reproductive and hepatic toxicity inferred from a genomic study of triazole antifungals.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 110, Issue:2

    Topics: Aging; Animals; Antifungal Agents; Chemical and Drug Induced Liver Injury; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Gestational Age; Infertility, Male; Liver; Liver Diseases; Male; Nitriles; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; Reproduction; Testis; Testosterone; Triazoles

2009
In vitro hepatic metabolism explains higher clearance of voriconazole in children versus adults: role of CYP2C19 and flavin-containing monooxygenase 3.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:1

    Topics: Adult; Aging; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Biocatalysis; Child; Child, Preschool; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; Kinetics; Liver; Microsomes, Liver; Middle Aged; Models, Biological; Oxygenases; Pyrimidines; Triazoles; Voriconazole; Young Adult

2010
Deferasirox decreases age-associated iron accumulation in the aging F344XBN rat heart and liver.
    Cardiovascular toxicology, 2010, Volume: 10, Issue:2

    Topics: Aging; Animals; Apoptosis; Benzoates; Body Weight; Deferasirox; Heart; In Situ Nick-End Labeling; Iron; Iron Chelating Agents; Iron Overload; Liver; Male; Myocardium; Myocytes, Cardiac; Organ Size; Rats; Rats, Inbred F344; Trace Elements; Triazoles

2010
Protective effect of caffeine and a selective A2A receptor antagonist on impairment of memory and oxidative stress of aged rats.
    Experimental gerontology, 2011, Volume: 46, Issue:4

    Topics: Adenosine A2 Receptor Antagonists; Aging; Animals; Ascorbic Acid; Brain; Caffeine; Male; Memory; Memory Disorders; Oxidative Stress; Pyrimidines; Rats; Rats, Wistar; Reactive Nitrogen Species; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase; Triazoles

2011
Dipeptidyl peptidase IV inhibition attenuates blood pressure rising in young spontaneously hypertensive rats.
    Journal of hypertension, 2011, Volume: 29, Issue:3

    Topics: Aging; Animals; Blood Pressure; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Hypertension; Kidney; Kidney Tubules, Proximal; Male; Pyrazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sitagliptin Phosphate; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Triazoles

2011
Postmenopausal hypertension: role of 20-HETE.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 300, Issue:6

    Topics: Aging; Animals; Blood Pressure; Cytochrome P-450 CYP4A; Disease Models, Animal; Female; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Postmenopause; Rats; Rats, Inbred SHR; Triazoles

2011
Enhanced role of adenosine A(2A) receptors in the modulation of LTP in the rat hippocampus upon ageing.
    The European journal of neuroscience, 2011, Volume: 34, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Aging; Animals; Electrophysiology; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Long-Term Potentiation; Male; Memory Disorders; N-Methylaspartate; Neuronal Plasticity; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Synaptic Transmission; Triazoles; Xanthines

2011
Effects of nefazodone on voluntary ethanol consumption induced by isolation stress in young and aged rats.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 73, Issue:3

    Topics: Aging; Alcohol Drinking; Animals; Antidepressive Agents, Second-Generation; Anxiety; Corticosterone; Female; Hippocampus; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Social Isolation; Stress, Psychological; Triazoles

2002
Enhanced adenosine A2A receptor facilitation of synaptic transmission in the hippocampus of aged rats.
    Journal of neurophysiology, 2003, Volume: 90, Issue:2

    Topics: Adenosine; Adrenergic beta-Agonists; Aging; Animals; Blotting, Western; Cyclic AMP; Electrophysiology; Excitatory Postsynaptic Potentials; Hippocampus; Isoproterenol; Male; Neurons; Phenethylamines; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Synaptic Transmission; Triazines; Triazoles; Xanthines

2003
[REPORT ON THE EFFECTS OF 3-AMINO-1,2,4-TRIAZOLE ON THE ACTIVITY OF HEPATIC CATALASE, AND HEPATIC CELLS IN MICE].
    Showa Igakkai zasshi = The Journal of the Showa Medical Association, 1963, Volume: 23

    Topics: Aging; Amitrole; Animals; Catalase; Cell Division; Hepatocytes; Liver; Mice; Pharmacology; Physiology; Research; Triazoles

1963
Top 10 health stories of 2003.
    Harvard health letter, 2003, Volume: 29, Issue:2

    Topics: Aging; Angioplasty, Balloon, Coronary; Antineoplastic Agents; Breast Neoplasms; Dietary Carbohydrates; Disease Outbreaks; Genome, Human; Guideline Adherence; Hormone Replacement Therapy; Humans; Hypertension; Letrozole; Myocardial Infarction; Nitriles; Obesity; Public Health; Severe Acute Respiratory Syndrome; Triazoles

2003
Effect of free radicals on adenosine A(2A) and dopamine D2 receptors in the striatum of young adult and aged rats.
    Neurochemistry international, 2004, Volume: 45, Issue:5

    Topics: Aging; Animals; Dopamine Antagonists; Free Radicals; In Vitro Techniques; Lipid Peroxidation; Male; Membranes; Neostriatum; Neuroprotective Agents; Pyrimidines; Raclopride; Rats; Receptor, Adenosine A2A; Receptors, Dopamine D2; Triazoles

2004
Potential role of inducible nitric oxide synthase in the sleep-wake states occurrence in old rats.
    Neuroscience, 2005, Volume: 135, Issue:2

    Topics: Age Factors; Aging; Analysis of Variance; Animals; Behavior, Animal; Brain; Electrochemistry; Electroencephalography; Enzyme Inhibitors; Guanidines; Immunohistochemistry; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Sleep; Sleep, REM; Time Factors; Triazoles; Wakefulness

2005
Adenosine A2A receptor modulation of juvenile female rat skeletal muscle microvessel permeability.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:6

    Topics: Adenine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aging; Animals; Arterioles; Cell Membrane Permeability; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression Regulation; Muscle, Skeletal; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; RNA, Messenger; Serum Albumin; Triazines; Triazoles; Vasodilator Agents; Venules

2006
Ontogeny of androgen and estrogen receptor expression in porcine testis: effect of reducing testicular estrogen synthesis.
    Animal reproduction science, 2007, Volume: 102, Issue:3-4

    Topics: Aging; Animals; Aromatase Inhibitors; Blotting, Western; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Immunohistochemistry; Letrozole; Male; Nitriles; Receptors, Androgen; Sertoli Cells; Swine; Testis; Triazoles

2007
Aromatization of androgens is important for skeletal maintenance of aged male rats.
    Calcified tissue international, 1996, Volume: 59, Issue:3

    Topics: Absorptiometry, Photon; Aging; Amino Acids; Analysis of Variance; Androgens; Animals; Aromatase Inhibitors; Bone Density; Bone Development; Bone Resorption; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrogens; Femur; Lumbar Vertebrae; Male; Orchiectomy; Osteocalcin; Osteoporosis; Rats; Rats, Wistar; Triazoles

1996
Myocardial adenosine A1 and A2 receptor activities during juvenile and adult stages of development.
    The American journal of physiology, 1996, Volume: 271, Issue:1 Pt 2

    Topics: Adenosine; Aging; Animals; Coronary Vessels; Drug Synergism; Heart; Isoproterenol; Male; Myocardial Contraction; Myocardium; Osmolar Concentration; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Triazoles; Veins; Xanthines

1996
Aromatase inhibition impairs skeletal modeling and decreases bone mineral density in growing male rats.
    Endocrinology, 1997, Volume: 138, Issue:6

    Topics: Absorptiometry, Photon; Aging; Animals; Aromatase Inhibitors; Body Weight; Bone Density; Bone Development; Bone Remodeling; Enzyme Inhibitors; Femur; Insulin-Like Growth Factor I; Male; Orchiectomy; Rats; Rats, Wistar; Reference Values; Triazoles

1997
Physiological plasma levels of androgens reduce bone loss in the ovariectomized rat.
    The American journal of physiology, 1998, Volume: 274, Issue:2

    Topics: Aging; Anastrozole; Androgen Antagonists; Androstenedione; Anilides; Animals; Body Weight; Bone Resorption; Enzyme Inhibitors; Estradiol; Female; Nitriles; Ovariectomy; Rats; Rats, Sprague-Dawley; Testosterone; Tosyl Compounds; Triazoles

1998
Adenosine A1 and A2A receptor antagonists stimulate motor activity: evidence for an increased effectiveness in aged rats.
    Neuroscience letters, 1998, Jul-31, Volume: 251, Issue:3

    Topics: Aging; Animals; Male; Motor Activity; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Theophylline; Triazoles

1998
Increase in the number, G protein coupling, and efficiency of facilitatory adenosine A2A receptors in the limbic cortex, but not striatum, of aged rats.
    Journal of neurochemistry, 1999, Volume: 73, Issue:4

    Topics: Adenosine; Aging; Animals; Cell Membrane; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Dentate Gyrus; GTP-Binding Proteins; Kinetics; Limbic System; Male; Organ Specificity; Phenethylamines; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazines; Triazoles; Tritium

1999
Cross talk between A(1) and A(2A) adenosine receptors in the hippocampus and cortex of young adult and old rats.
    Journal of neurophysiology, 1999, Volume: 82, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Aging; Animals; Binding, Competitive; Cerebral Cortex; Electrophysiology; Hippocampus; In Vitro Techniques; Male; Phenethylamines; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor Cross-Talk; Receptor, Adenosine A2A; Receptors, Purinergic P1; Synaptic Membranes; Triazines; Triazoles; Xanthines

1999
Tonic adenosine neuromodulation is preserved in motor nerve endings of aged rats.
    Neurochemistry international, 2000, Volume: 36, Issue:7

    Topics: Acetylcholine; Adenosine; Aging; Animals; Electric Stimulation; Male; Motor Neurons; Nerve Endings; Neurotransmitter Agents; Phrenic Nerve; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Triazines; Triazoles; Xanthines

2000
Striatal A2A adenosine receptor antagonism differentially modifies striatal glutamate outflow in vivo in young and aged rats.
    Neuroreport, 2000, Aug-03, Volume: 11, Issue:11

    Topics: Adenosine; Age Factors; Aging; Animals; Aspartic Acid; Glutamic Acid; Male; Neostriatum; Neurons; Neuroprotective Agents; Potassium; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Time Factors; Triazoles

2000
Skeletal effects of estrogen deficiency as induced by an aromatase inhibitor in an aged male rat model.
    Bone, 2000, Volume: 27, Issue:5

    Topics: Aging; Animals; Aromatase Inhibitors; Body Weight; Bone and Bones; Bone Density; Bone Remodeling; Enzyme Inhibitors; Estradiol; Estrogens; Male; Models, Animal; Rats; Rats, Wistar; Triazoles

2000
A microsomal ecdysone-binding cytochrome P450 from the insect Locusta migratoria purified by sequential use of type-II and type-I ligands.
    Biological chemistry, 2001, Volume: 382, Issue:11

    Topics: Aging; Animals; Aryl Hydrocarbon Hydroxylases; Chromatography, Ion Exchange; Cytochrome P-450 Enzyme System; Durapatite; Ecdysone; Grasshoppers; Indicators and Reagents; Ligands; Malpighian Tubules; Microsomes; NADPH-Ferrihemoprotein Reductase; Sepharose; Solvents; Steroid Hydroxylases; Triazoles

2001
The effect of 1,2,4-thiotriazolyl 5-mercaptoacetic acid new derivatives on lipid peroxidation in the heart from adult and old rats during stress.
    Experimental gerontology, 2002, Volume: 37, Issue:4

    Topics: Acetates; Aging; Animals; Antioxidants; Lipid Peroxidation; Male; Myocardium; Rats; Rats, Wistar; Stress, Physiological; Thioglycolates; Triazoles

2002
Chronic toxicity and carcinogenicity studies with FWAs.
    Environmental quality and safety. Supplement, 1975, Volume: 4

    Topics: Aging; Animals; Biphenyl Compounds; Body Weight; Carcinogens; Coloring Agents; Diet; Dogs; Female; Male; Organ Size; Rats; Species Specificity; Stilbenes; Triazoles

1975
A new non-hormonal antifertility drug DL 111-IT: II. Effects on testicular hyaluronidase activity in male rats.
    Contraception, 1986, Volume: 33, Issue:1

    Topics: Abortifacient Agents; Abortifacient Agents, Nonsteroidal; Aging; Animals; Follicle Stimulating Hormone; Gonadotropins, Equine; Hyaluronoglucosaminidase; Kinetics; Luteinizing Hormone; Male; Rats; Rats, Inbred Strains; Sexual Maturation; Testis; Testosterone; Triazoles

1986
Anterior chamber hydrogen peroxide: effects of 3-aminotriazole on peroxide kinetics and on the status of glutathione.
    Basic life sciences, 1988, Volume: 49

    Topics: Aging; Amitrole; Animals; Anterior Chamber; Catalase; Glutathione; Hydrogen Peroxide; Kinetics; Rabbits; Reference Values; Triazoles

1988
Morphological sequelae of anterior segment hydrogen peroxide in young and adult rabbits with or without 3-aminotriazole treatment.
    Basic life sciences, 1988, Volume: 49

    Topics: Aging; Amitrole; Animals; Anterior Chamber; Catalase; Ciliary Body; Endothelium, Corneal; Hydrogen Peroxide; Rabbits; Reference Values; Triazoles

1988
3-amino-triazole effects on the eye of young and adult rabbits in the presence and absence of hydrogen peroxide.
    Current eye research, 1987, Volume: 6, Issue:12

    Topics: Administration, Oral; Aging; Amitrole; Animals; Anterior Eye Segment; Ciliary Body; Endothelium, Corneal; Eye; Hydrogen Peroxide; Injections, Intravenous; Rabbits; Time Factors; Triazoles

1987
Regulation of catalase activity in mice of different ages.
    Gerontologia, 1971, Volume: 17, Issue:2

    Topics: Age Factors; Aging; Animals; Catalase; Injections, Intraperitoneal; Kidney; Liver; Male; Mice; Triazoles

1971