Page last updated: 2024-08-24

triazoles and Acute Liver Injury, Drug-Induced

triazoles has been researched along with Acute Liver Injury, Drug-Induced in 113 studies

Research

Studies (113)

TimeframeStudies, this research(%)All Research%
pre-19906 (5.31)18.7374
1990's5 (4.42)18.2507
2000's30 (26.55)29.6817
2010's59 (52.21)24.3611
2020's13 (11.50)2.80

Authors

AuthorsStudies
Li, AP; Wei, H1
Chang, J; Hao, W; Li, J; Pan, Y; Xie, Y1
Leong, R; O'Flynn, R; Straus, W; Waskin, H; Zhou, YP1
DiNardo, CD; DiPippo, AJ; Jiang, Y; Kadia, T; Kontoyiannis, DP; Maiti, A; Montalban-Bravo, G; Rausch, CR; Ravandi, F1
Chen, Y; Ding, S; Liu, S; Peng, Y; Zheng, J1
Chen, X; Li, Y; Xue, J; Zhao, Y1
Albrecht, W1
Chen, L; Coffin, S; Gui, W; Jiang, Y; Li, S; Qiao, K; Sun, Q; Zhu, G1
Chang, Y; Jiang, H; Mao, L; Zhang, L; Zhang, Y1
Berrouague, S; Boumendjel, A; Boumendjel, M; Khaldi, T; Messarah, M; Rouag, M; Taibi, F1
Abd Eldaim, MA; Abdallah, AEM; Abdel-Daim, MM; Abdelaziz, SAM; Abdul Rashid, S; Abdullah, AS; Abdullah, LC; Abramson, MJ; Ahmed, HB; Ahmed, MM; Ahn, YC; Alexander, DC; Ando, T; Angelone, AM; Anglani, F; Ap, Y; Arthanari, SK; Axelrad, C; Bai, S; Bakonyi, P; Barnes, E; Beckmann, NA; Bélafi-Bakó, K; Bennett, CM; Bestha, RM; Bitsch, RG; Bradley, CA; Bu, Y; Calò, LA; Cañedo-Villaroya, E; Carlson, L; Caruso, S; Casado-Flores, J; Ceol, M; Cesarino, I; Chen, IL; Chen, R; Chen, X; Chilvers, MI; Cho, WK; Choong, TSY; Conceição-Neto, N; Culver, EL; Dai, X; de Lama Caro-Patón, G; De Rosa, I; Del Prete, D; Dharmage, SC; Dimitriadis, E; Dittakavi, S; Dobrowolski, JC; Edin, S; Elgarawany, GE; Emam, HE; Emmens, RW; Erbas, B; Erwich, JJHM; Farghali, M; Feng, L; Funston, RN; Gabler, NK; Gale, P; Ganesh, M; Gao, J; Gao, L; Gao, X; García-Salido, A; Gatto, R; Gautam, S; Ge, C; Ghogomu, SM; Gianesello, L; Gonçales, VR; Gooch, JL; Gooding, JJ; Gourley, GG; Gu, H; Gu, X; Gu, Z; Guerreri, M; Guillén, M; Hazzaa, SM; Heylen, E; Hicks, R; Hong, X; Hoshi, M; Hu, B; Hu, LX; Hu, R; Hu, S; Huang, J; Huang, K; Hubbard, WB; Hui, J; Hwang, NY; Iannacci, J; Ianus, A; Iglesias-Bouzas, MI; Ihara, I; Iwasaki, M; Jaeger, S; Kandel, YR; Karpińska, G; Kim, HK; Klopfenstein, TJ; Knorr, D; Koók, L; Kotb, S; Kruithof, S; Larsson, P; Laurence, C; Leng, J; Li, H; Li, J; Li, Q; Li, S; Li, X; Li, Z; Lian, J; Liang, JX; Liang, X; Lighaam, LC; Lin, CW; Lin, HC; Lin, J; Ling, A; Liu, J; Liu, P; Liu, YS; Ljuslinder, I; Lo, GH; Lodge, CJ; Löfgren-Burström, A; Lowe, AJ; Lu, M; Lu, N; Lucero-Prisno, DE; Luebbe, KM; Luo, X; Ma, Z; Maes, P; Makuch, M; Malekbala, MR; Mao, Z; Martínez-Romera, I; Marzo, G; Mathew, FM; Mattei, A; Matthijnssens, J; Mayumi, M; Morita, N; Mueller, DS; Mullangi, R; Mummolo, S; Murthi, P; Myte, R; Nabeshima, T; Nakamoto, K; Nehdi, IA; Nemestóthy, N; Niessen, HWM; Noh, JM; Nota, A; Nunes, D; Oh, D; Öhlund, D; Olsen, KM; Ono, H; Osawa, Y; Palmqvist, R; Palombo, M; Park, M; Patience, JF; Peng, Y; Perng, DS; Persano, A; Priante, G; Prince, SJ; Pulipati, S; Pyo, H; Qiu, X; Quan, J; Quaranta, F; Quinzi, V; Rademacher, CJ; Rajaraman, G; Rashid, U; Rauch, JC; Rector, A; Remmerswaal, EBM; Ren, R; Rispens, T; Rocha, GS; Saad, NM; Saito, K; Salamova, A; Sarfaraz, K; Satoshi, A; Schnellmann, RG; Scholpa, NE; Schonhoff, M; Schwartz, KJ; Schwarze, M; Schweer, WP; Seiichi, Y; Serrano-González, A; Severino, J; Shemesh, N; Shi, ZQ; Shike, DW; Shim, YM; Siciliano, PA; Siebenrock, KA; Silva, MKL; Smith, DL; Soltani, S; Song, YM; Spry, ML; Stalker, LA; Stokes, RS; Sullivan, PG; Sun, JM; Sun, S; Svanes, C; Syo, K; Tai, CM; Takashima, S; Tashita, C; Taurino, A; Ten Berge, IJM; Tenuta, AU; Teo, SH; Tilley, RD; Trivedi, RK; Umetsu, K; Unger, PA; van Bruggen, R; van Ham, SM; Van Ranst, M; Vanitha, J; Vekaria, HJ; Venier, M; Venkateshwaran, K; Venkert, A; Vermeulen, E; Wan, C; Wang, H; Wang, N; Wang, P; Wang, T; Wang, X; Wang, Y; Wise, KA; Wolbink, GJ; Wu, J; Wu, P; Wu, S; Wu, Y; Xia, Q; Xin, W; Xiong, Q; Xu, H; Xu, P; Xue, S; Yamamoto, Y; Yamashiro, T; Yan, F; Yan, H; Yan, S; Yan, Y; Yang, JM; Yang, L; Yang, P; Ye, W; Yeh, JH; Yinda, CK; Ying, GG; Ying, L; Yoon, HG; Yu, H; Zainuddin, M; Zakkula, A; Zeller, M; Zeng, Y; Zha, J; Zhang, F; Zhang, H; Zhang, M; Zhang, Q; Zhang, S; Zhang, T; Zhang, Z; Zhao, C; Zhao, J; Zhao, Y; Zhong, Q; Zhu, J; Zingmark, C; Zo, JI; Zou, Y1
Akakpo, S; Chalon, S; Chughlay, MF; Csermak-Renner, K; Djeriou, E; Gaur, AH; Leboulleux, D; McCarthy, J; Odedra, A; Shanks, GD; Winnips, C1
Chen, L; Jiang, J; Liu, X; Lv, L; Wang, Q; Wu, S; Zhao, X1
Chhonker, Y; Haney, SL; Holstein, SA; Murry, DJ; Smith, LM; Talmon, G; Varney, ML1
Han, J; Ji, X; Qian, M; Wang, J; Wu, H; Wu, S; Xu, J; Zhang, H1
Adas, M; Bechman, K; Clarke, B; Galloway, J; Yates, M1
Aitken, SL; Brown, JE; Buege, MJ1
Bando, K; Ito, K; Nakagawa, T; Ogimura, E; Sekine, S; Tokizono, M1
Delacruz, J; Gedrimaite, Z; Han, Z; Hsu, M; Miceli, MH; Narayanan, PP; Paskovaty, A; Perissinotti, AJ; Pettit, NN; Pisano, J; Rivera, CG; Seo, SK; Steinbeck, J1
Abdelhadya, DH; El-Magd, MA; Elbialy, ZI; Saleh, AA1
Liang, X; Martyniuk, CJ; Wang, Z; Zha, J; Zhao, J1
Bkhairia, I; Ghozzi, H; Hakim, A; Harrabi, B; Jamoussi, K; Kallel, C; Kasmi, S; Marrakchi, R; Mnif, H; Nasri, M; Zeghal, K1
Chen, C; Chen, K; Huang, LY; Jin, XT; Li, LL; Lin, GF; Lu, GW; Sun, QZ; Wei, YQ; Xiang, R; Yang, SY; Yang, W; Zhang, G1
Geburek, I; Haider, W; Heise, T; Knebel, C; Marx-Stoelting, P; Niemann, L; Rieke, S; Schmidt, F1
Ko, S; Monga, SP; Poddar, M; Russell, JO; Saggi, HS; Shin, D; Singh, S1
DiPippo, AJ; Kontoyiannis, DP; Rausch, CR1
Girmenia, C; Goffredo, BM; Marchesi, F; Mengarelli, A; Menna, P; Minotti, G; Romano, A; Salvatorelli, E1
Fan, Q; Hu, W; Hu, X; Huang, W; Ji, Y; Li, X; Li, Y; Lu, X; Pei, F; Tang, Y; Wang, Z; Zhao, H1
Aslamkhan, AG; Gonzalez, R; Imredy, J; Kaczor, A; Kuhls, M; Lebron, J; Liaw, A; Liu, L; Mitra, K; Pearson, K; Ruth, M; Sistare, FD; Vu, H; Wei, C; Xu, Q; Yu, Y1
Lacombe, K; Surgers, L1
Barrette, S; Files, B; Habr, D; Minniti, CP; Torres, M; Vichinsky, E; Zhang, Y1
Degli Antoni, A; Ferrari, C; Fragola, V; Manfredi, R; Weimer, LE1
Korytova, LI; Masliukova, EA; Meshechkin, AV; Sokurenko, VP; Zhabina, RM1
Chou, HC; Hsiao, FY; Huang, WF; Tsai, YW1
Davis, K; Fabian, E; Greenhaw, J; Groeters, S; Herold, M; Kamp, H; Looser, R; Marxfeld, H; Mattes, W; Mellert, W; Moeller, N; Montoya-Parra, G; Prokoudine, A; Strauss, V; van Ravenzwaay, B; Walk, T1
Haider, W; Heise, T; Knebel, C; Kneuer, C; Marx-Stoelting, P; Niemann, L; Pfeil, R; Rieke, S; Schmidt, F1
Evans, A; Lacey, R1
Hachulla, E; Kahl, L; Layton, M; Machado, D; Patel, J; Schifano, L; Staumont-Sallé, D; van Vollenhoven, RF1
Gu, A; Huan, F; Jiang, Z; Liu, Q; Liu, W; Qu, J; Wang, Y; Xu, C1
Attri, SV; Bansal, D; Bhatia, P; Marwaha, RK; Totadri, S; Trehan, A1
Fukami, T; Nakajima, M; Oda, S; Takai, S; Tsuneyama, K; Yokoi, T1
Islam, MS; Lucas, R; Tanner, P; Wright, G1
Carbonari, DM; Corley, DA; Forde, KA; Goldberg, DS; Haynes, K; Lewis, JD; Lo Re, V; Marks, AR; Reddy, KR; Roy, JA; Schneider, JL; Sha, D; Strom, BL1
Isin, EM; Mettetal, JT; Ogese, MO; Thompson, RA; Williams, DP1
Chanda, S; Coronado, D; Del Rosso, J; Zane, LT1
Chang, J; Garner, CE; Huang, C; Ichihara, G; Ichihara, S; Ito, H; Kato, M; Sakurai, T; Toyokuni, S; Zhang, L; Zhang, X; Zong, C1
Ema, M; Hirata-Koizumi, M; Hirose, A; Ise, R; Kato, H; Matsuyama, T; Nishimaki-Mogami, T; Ono, A; Takahashi, M1
Groll, AH; Kyriakidis, I; Munchen, S; Tragiannidis, A1
Braeuning, A; Ganzenberg, K; Hammer, H; Knebel, C; Marx-Stoelting, P; Pötz, O; Rieke, S; Schmidt, F; Schwarz, M1
Owens, B1
Arribas López, JR1
Dix, DJ; Goetz, AK1
Amigues, I; Barker, J; Chung, D; Cohen, N; Jakubowski, A; Papanicolaou, GA; Plescia, C; Seo, SK1
Babatz, J; Ehninger, G; Illmer, T; Pursche, S; Schaich, M; Schuler, U; Stölzel, F1
Alçin, E; Aydin, M; Nacar, A; Oktar, S; Ozkan, OV; Oztürk, OH1
Inoue, T; Kakita, T; Matsuda, H; Mori, T; Nagatoya, K; Teranishi, J; Yamauchi, Y1
Aslam, N; Marsano-Obando, LS; Martin, A; Mettu, P1
Atsumi, R; Izumi, T; Nakazawa, T; Okazaki, O; Saji, H; Shimizu, S; Sudo, K1
Bedouch, P; Belaiche, S; Pison, C; Quetant, S; Roustit, M; Saint-Raymond, C1
Moore, T; Nesnow, S; Padgett, WT1
Jarque, I; Salavert, M1
Hibi, T; Kaneko, F; Motoori, T; Oda, M; Ohbu, M; Shimizu, Y; Tahara, K; Takeuchi, H; Toyoda-Akui, M; Yokomori, H1
Al-Rousan, RM; Blough, ER; Katta, A; Laurino, J; Rice, KM; Triest, WE; Walker, EM; Wu, M1
Imran, FS; Phatak, P1
Acquaviva, J; Barsoum, J; Blackman, RK; Du, Z; Foley, KP; Inoue, T; Koya, K; Ogawa, LS; Proia, DA; Sang, J; Sun, L; Tatsuta, N; Wada, Y; Ye, S; Ying, W; Zhou, D1
Hester, S; Moore, T; Murphy, L; Nesnow, S; Padgett, WT; Wood, CE1
Bayrak, A; Coskun, Y; Erarslan, E; Koç, H; Uflaz, B; Yüksel, I1
Ieda, M; Kobayashi, D; Ohshima, S; Yamamoto, M1
Chen, Y; Groothuis, GM; Hadi, M; Merema, MT; Starokozhko, V1
Eun, CJ; Han, E; Kim, JA; Song, JM; Tak, YK1
Auzinger, G; Bernal, W; Heneghan, MA; López, JC; Solís-Muñoz, P; Verma, A; Wendon, J; Willars, C1
Casas, M; Dalmau, B; Fernandez-Atutxa, A; Gil, M; Miquel, M; Sanchez-Delgado, J; Vergara, M1
Hidalgo-Castellón, AJ; Pérez, MA; Ramos-Clemente, JI1
Muller, CD; Peluso, J; Saab, L; Ubeaud-Sequier, G1
Ehrentraut, S; Gerbes, AL; Kapfhammer, HP; Rau, HG; Rothenhäusler, HB; Schirren, CA; Thiel, M1
Edwards, IR1
Bate, A; Hägg, S; Spigset, O1
Choi, S1
Arteel, GE; Bradford, BU; Connor, HD; Froh, M; Isayama, F; Kadiiska, MB; Koop, DR; Mason, RP; McKim, SE; Wheeler, MD1
Buclin, T; Genton, A1
Cabantchik, ZI; Hershko, CM; Konijn, AM; Link, GM1
Deresinski, S; Song, JC1
Brayshaw, N; Tan, K; Tomaszewski, K; Troke, P; Wood, N1
Ammar, H; Malani, AK1
Blijlevens, NM; Donnelly, JP; Klont, RR; van der Velden, WJ; Verweij, PE1
Bujanda, L; Piérola, A; Zapata, E; Zubiaurre, L1
Carlini, P; Ciccarese, M; Cognetti, F; Fabi, A; Felici, A; Ferretti, G; Milella, M; Nuzzo, C; Papaldo, P; Ruggeri, EM1
de la Cruz, L; Herrerias-Gutierrez, JM; Jiménez-Sáenz, M; Padron, JR; Romero-Vazquez, J1
Ayanoglu, E; Brennan, RJ; Corton, JC; Dix, DJ; Hu, W; Kavlock, RJ; Lau, C; Martin, MT; Ren, H; Wood, CR1
Krause, DS1
Foo, H; Gottlieb, T1
den Hollander, JG; Levin, MD; Rijnders, BJ; Sonneveld, P; van der Holt, B; van Schaik, RH; van Vliet, M1
Amir, M; Javed, SA; Kumar, H1
Vichinsky, E1
Ahmad, S; Barrish, JC; Bird, E; Bisaha, S; Blanar, MA; Chang, M; Chen, BC; Chen, X; Cuff, CA; Darienzo, CJ; Giancarli, M; Harrity, T; Huang, C; Janovitz, E; Kennedy, LJ; Li, T; Madsen, CS; Monshizadegan, H; Ngu, K; Nguyen-Tran, V; Reeves, RA; Robl, JA; Ryan, CS; Search, D; Setters, R; Sitkoff, D; Stein, PD; Yin, X; Zahler, R; Zhang, R; Zhao, R; Zhuang, S1
Gearhart, MO1
Han, K; Hashimoto, N; Hikiba, Y; Kawase, T; Komatsu, Y; Okano, K; Omata, M; Shiratori, Y; Yoshida, H1
Bailie, MB; Fink, GD; Pearson, JM; Roth, RA1
Roberts-Thompson, IC; Schrader, GD1
Eloubeidi, MA; Gaede, JT; Swaim, MW1
Begay, CK; Gandolfi, AJ; Lind, RC1
Anaissie, E; Arndt, C; Donowitz, G; Finberg, R; Fioritoni, G; Garber, G; Greenberg, R; Hadley, S; Laverdière, M; Lazarus, HM; Lee, J; Pappas, P; Perfect, J; Petersen, F; Raffalli, J; Reboli, A; Reinhardt, J; Schuster, M; Stiff, P; Walsh, TJ; Wingard, J; Winston, DJ; Yanovich, S1
Carvajal García-Pando, A; García del Pozo, J; Lucena, MI; Rueda de Castro, AM; Sánchez, AS; Velasco, MA1
Schwetz, BA1
Stewart, DE1
Ayala, E; Canonico, PG; Rill, W1
Butler, WH; Magos, L; Snowden, R1
Inatsu, Y; Ishii, H; Ninobe, S; Suga, T1
Zhang, F1
Johnson, EA; Stenger, RJ1
Göttinger, E1
Vasil'eva, NN1

Reviews

12 review(s) available for triazoles and Acute Liver Injury, Drug-Induced

ArticleYear
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Amylose; Anaerobiosis; Animals; Anti-Bacterial Agents; Anura; Arginase; Arthritis, Rheumatoid; Asthma; Atmosphere; B-Lymphocytes; Basic Helix-Loop-Helix Transcription Factors; Bioelectric Energy Sources; Biofilms; Biofuels; Biomarkers; Biopolymers; Bioreactors; Brain; Brain Injuries, Traumatic; Breast Neoplasms; Calibration; Carbon Tetrachloride; Caspase 3; Catalysis; Catechin; Cations; Cattle; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Body; Cell Line, Tumor; Cell Plasticity; Chemical and Drug Induced Liver Injury; Chemistry Techniques, Synthetic; China; Chitosan; Chloride Channels; Chromatography, High Pressure Liquid; Chromosome Mapping; Cognition; Cognitive Dysfunction; Cohort Studies; Colitis, Ulcerative; Colloids; Coloring Agents; Congresses as Topic; Correlation of Data; Crystallization; Cyanoacrylates; Cyclohexane Monoterpenes; Cyprinidae; Cytochrome P-450 CYP1A1; Death, Sudden; Dent Disease; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Disease Progression; Disease Resistance; Disulfides; Drug Monitoring; Drug Stability; Ecotoxicology; Electricity; Electrodes; Endocytosis; Environmental Exposure; Environmental Monitoring; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal and Gastric Varices; Esters; Fagopyrum; Female; Ferrosoferric Oxide; Flame Retardants; Flavobacteriaceae; Flow Cytometry; Follow-Up Studies; Formoterol Fumarate; Fusarium; Garlic; Gastrointestinal Hemorrhage; Gene Expression; Genes, Plant; Genetic Markers; Glial Fibrillary Acidic Protein; Gliosis; Global Health; Glutathione Transferase; Glycine max; Gum Arabic; Hemostasis, Endoscopic; Hepatocytes; Hippocampus; Humans; Hydrogen-Ion Concentration; Illinois; Immunoglobulin G; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infant, Newborn; Infant, Small for Gestational Age; Injections, Intraperitoneal; Interleukin-4; Iowa; Iron; Ki-67 Antigen; Kidney; Kinetics; Kynurenine; Lakes; Levofloxacin; Lipid Peroxidation; Lipids; Liver; Liver Cirrhosis, Experimental; Magnetic Fields; Magnetic Iron Oxide Nanoparticles; Male; Manure; Maze Learning; Memory, Short-Term; Metal Nanoparticles; Metals, Heavy; Methane; Mice; Mice, Inbred C57BL; Mice, Knockout; Michigan; Microalgae; Microbial Consortia; Mitochondria; Models, Animal; Models, Chemical; Models, Neurological; Molecular Structure; Molecular Weight; Mutation; Myeloid-Derived Suppressor Cells; NADPH Oxidase 2; Neoplasm Recurrence, Local; Neurites; Neurons; Neuroprotective Agents; NF-kappa B; NIH 3T3 Cells; Nitric Oxide Synthase Type II; Nitrogen; Ohio; Ointments; Ontario; Organelle Biogenesis; Organophosphates; Organophosphorus Compounds; Oxidative Stress; Palladium; Particle Size; Pectins; Phenotype; Phytotherapy; Piperidines; Placenta; Plant Diseases; Plant Extracts; Polymers; Polymorphism, Genetic; Polyphenols; Powders; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Protein Kinase Inhibitors; Protein Structure, Secondary; Proteins; Pyridines; Pyrimidines; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; Recovery of Function; Recurrence; Reference Standards; Reference Values; Reproducibility of Results; Respiratory Function Tests; Retrospective Studies; Risk; Sensitivity and Specificity; Sewage; Signal Transduction; Sodium Glutamate; Soil; Solanum tuberosum; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spermatozoa; STAT3 Transcription Factor; Sulfamethoxazole; Tea; Temperature; Thermodynamics; Thrombin; Treatment Outcome; Triazoles; United States; Viscosity; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical; Water Purification; White Matter; Wisconsin; X-Ray Diffraction; Zea mays

2013
The safety of JAK-1 inhibitors.
    Rheumatology (Oxford, England), 2021, 05-05, Volume: 60, Issue:Suppl 2

    Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Diverticular Diseases; Herpes Simplex; Herpes Zoster; Heterocyclic Compounds, 3-Ring; Humans; Immunocompromised Host; Infections; Intestinal Perforation; Janus Kinase 1; Janus Kinase Inhibitors; Latent Infection; Opportunistic Infections; Pyridines; Triazoles

2021
Solithromycin: A novel ketolide antibiotic.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2017, Jun-15, Volume: 74, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Community-Acquired Infections; Drug Approval; Drug Resistance, Bacterial; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Pneumonia, Bacterial; Triazoles; United States; United States Food and Drug Administration

2017
Hepatoxicity of new antiretrovirals: a systematic review.
    Clinics and research in hepatology and gastroenterology, 2013, Volume: 37, Issue:2

    Topics: Anti-Retroviral Agents; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cyclohexanes; Darunavir; Heterocyclic Compounds, 3-Ring; Humans; Maraviroc; Nitriles; Oxazines; Piperazines; Pyridazines; Pyridones; Pyrimidines; Pyrrolidinones; Quinolones; Raltegravir Potassium; Rilpivirine; Sulfonamides; Triazoles

2013
Reactive Metabolites: Current and Emerging Risk and Hazard Assessments.
    Chemical research in toxicology, 2016, Apr-18, Volume: 29, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antidepressive Agents, Second-Generation; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Pharmaceutical Preparations; Piperazines; Risk Assessment; Triazoles

2016
Antifungal agents for onychomycosis: new treatment strategies to improve safety.
    Dermatology online journal, 2016, Mar-16, Volume: 22, Issue:3

    Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chemical and Drug Induced Liver Injury; Ciclopirox; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Itraconazole; Naphthalenes; Onychomycosis; Pyridones; Terbinafine; Triazoles

2016
Clinical hepatotoxicity associated with antifungal agents.
    Expert opinion on drug safety, 2017, Volume: 16, Issue:2

    Topics: Amphotericin B; Animals; Antifungal Agents; Chemical and Drug Induced Liver Injury; Drug Interactions; Echinocandins; Humans; Invasive Fungal Infections; Liver Function Tests; Triazoles

2017
[Secondary effects of treatment with maraviroc and other CCR5 antagonists. Potential impact of the CCR5 blocker].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 11

    Topics: Adult; Benzoates; CCR5 Receptor Antagonists; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Comorbidity; Cyclohexanes; Diketopiperazines; Disease Susceptibility; Drug Design; env Gene Products, Human Immunodeficiency Virus; HIV Fusion Inhibitors; HIV Infections; Homozygote; Humans; Hyperlipidemias; Incidence; Infections; Maraviroc; Membrane Fusion; Neoplasms; Piperazines; Receptors, CCR5; Sequence Deletion; Spiro Compounds; Triazoles; Virus Attachment; Virus Internalization

2008
[Is micafungin useful in the prophylaxis of invasive fungal disease in hematological patients?].
    Enfermedades infecciosas y microbiologia clinica, 2011, Volume: 29 Suppl 2

    Topics: Adult; Ambulatory Care; Antifungal Agents; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topic; Dose-Response Relationship, Drug; Echinocandins; Female; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Kidney Diseases; Lipopeptides; Male; Meta-Analysis as Topic; Micafungin; Mycoses; Postoperative Complications; Practice Guidelines as Topic; Triazoles

2011
Hepatotoxicity of antifungal agents.
    Current opinion in investigational drugs (London, England : 2000), 2005, Volume: 6, Issue:2

    Topics: Allylamine; Animals; Antifungal Agents; Chemical and Drug Induced Liver Injury; Flucytosine; Humans; Imidazoles; Polyenes; Triazoles

2005
Clinical application of deferasirox: practical patient management.
    American journal of hematology, 2008, Volume: 83, Issue:5

    Topics: Administration, Oral; Adult; Benzoates; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topic; Contraindications; Creatinine; Deferasirox; Disease Management; Drug Eruptions; Gastrointestinal Diseases; Hematologic Diseases; Hemosiderosis; Humans; Iron; Iron Chelating Agents; Iron Overload; Kidney Diseases; Transfusion Reaction; Triazoles

2008
Worsening of liver function with fluconazole and review of azole antifungal hepatotoxicity.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:10

    Topics: Administration, Oral; Alanine Transaminase; Aspartate Aminotransferases; Candidiasis; Chemical and Drug Induced Liver Injury; Female; Fluconazole; Hospitals, Teaching; Humans; Liver Diseases; Liver Function Tests; Middle Aged; Triazoles; Urinary Tract Infections

1994

Trials

4 trial(s) available for triazoles and Acute Liver Injury, Drug-Induced

ArticleYear
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Amylose; Anaerobiosis; Animals; Anti-Bacterial Agents; Anura; Arginase; Arthritis, Rheumatoid; Asthma; Atmosphere; B-Lymphocytes; Basic Helix-Loop-Helix Transcription Factors; Bioelectric Energy Sources; Biofilms; Biofuels; Biomarkers; Biopolymers; Bioreactors; Brain; Brain Injuries, Traumatic; Breast Neoplasms; Calibration; Carbon Tetrachloride; Caspase 3; Catalysis; Catechin; Cations; Cattle; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Body; Cell Line, Tumor; Cell Plasticity; Chemical and Drug Induced Liver Injury; Chemistry Techniques, Synthetic; China; Chitosan; Chloride Channels; Chromatography, High Pressure Liquid; Chromosome Mapping; Cognition; Cognitive Dysfunction; Cohort Studies; Colitis, Ulcerative; Colloids; Coloring Agents; Congresses as Topic; Correlation of Data; Crystallization; Cyanoacrylates; Cyclohexane Monoterpenes; Cyprinidae; Cytochrome P-450 CYP1A1; Death, Sudden; Dent Disease; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Disease Progression; Disease Resistance; Disulfides; Drug Monitoring; Drug Stability; Ecotoxicology; Electricity; Electrodes; Endocytosis; Environmental Exposure; Environmental Monitoring; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal and Gastric Varices; Esters; Fagopyrum; Female; Ferrosoferric Oxide; Flame Retardants; Flavobacteriaceae; Flow Cytometry; Follow-Up Studies; Formoterol Fumarate; Fusarium; Garlic; Gastrointestinal Hemorrhage; Gene Expression; Genes, Plant; Genetic Markers; Glial Fibrillary Acidic Protein; Gliosis; Global Health; Glutathione Transferase; Glycine max; Gum Arabic; Hemostasis, Endoscopic; Hepatocytes; Hippocampus; Humans; Hydrogen-Ion Concentration; Illinois; Immunoglobulin G; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infant, Newborn; Infant, Small for Gestational Age; Injections, Intraperitoneal; Interleukin-4; Iowa; Iron; Ki-67 Antigen; Kidney; Kinetics; Kynurenine; Lakes; Levofloxacin; Lipid Peroxidation; Lipids; Liver; Liver Cirrhosis, Experimental; Magnetic Fields; Magnetic Iron Oxide Nanoparticles; Male; Manure; Maze Learning; Memory, Short-Term; Metal Nanoparticles; Metals, Heavy; Methane; Mice; Mice, Inbred C57BL; Mice, Knockout; Michigan; Microalgae; Microbial Consortia; Mitochondria; Models, Animal; Models, Chemical; Models, Neurological; Molecular Structure; Molecular Weight; Mutation; Myeloid-Derived Suppressor Cells; NADPH Oxidase 2; Neoplasm Recurrence, Local; Neurites; Neurons; Neuroprotective Agents; NF-kappa B; NIH 3T3 Cells; Nitric Oxide Synthase Type II; Nitrogen; Ohio; Ointments; Ontario; Organelle Biogenesis; Organophosphates; Organophosphorus Compounds; Oxidative Stress; Palladium; Particle Size; Pectins; Phenotype; Phytotherapy; Piperidines; Placenta; Plant Diseases; Plant Extracts; Polymers; Polymorphism, Genetic; Polyphenols; Powders; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Protein Kinase Inhibitors; Protein Structure, Secondary; Proteins; Pyridines; Pyrimidines; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; Recovery of Function; Recurrence; Reference Standards; Reference Values; Reproducibility of Results; Respiratory Function Tests; Retrospective Studies; Risk; Sensitivity and Specificity; Sewage; Signal Transduction; Sodium Glutamate; Soil; Solanum tuberosum; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spermatozoa; STAT3 Transcription Factor; Sulfamethoxazole; Tea; Temperature; Thermodynamics; Thrombin; Treatment Outcome; Triazoles; United States; Viscosity; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical; Water Purification; White Matter; Wisconsin; X-Ray Diffraction; Zea mays

2013
Efficacy and safety of deferasirox compared with deferoxamine in sickle cell disease: two-year results including pharmacokinetics and concomitant hydroxyurea.
    American journal of hematology, 2013, Volume: 88, Issue:12

    Topics: Acute Kidney Injury; Adolescent; Adult; Anemia, Sickle Cell; Benzoates; Cellulitis; Chelation Therapy; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Deferasirox; Deferoxamine; Drug Therapy, Combination; Female; Ferritins; Humans; Hydroxyurea; Iron Chelating Agents; Iron Overload; Male; Middle Aged; Prospective Studies; Transfusion Reaction; Triazoles; Young Adult

2013
DRESS syndrome and reversible liver function abnormalities in patients with systemic lupus erythematosus treated with the highly selective JAK-1 inhibitor GSK2586184.
    Lupus, 2015, Volume: 24, Issue:6

    Topics: Adult; Azetidines; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity Syndrome; Female; Humans; Janus Kinase 1; Lupus Erythematosus, Systemic; Middle Aged; Protein Kinase Inhibitors; Randomized Controlled Trials as Topic; Triazoles

2015
Voriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent fever.
    The New England journal of medicine, 2002, Jan-24, Volume: 346, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Chemical and Drug Induced Liver Injury; Child; Chronic Disease; Female; Fever; Humans; Infusions, Intravenous; Male; Middle Aged; Mycoses; Neoplasms; Neutropenia; Prospective Studies; Pyrimidines; Triazoles; Voriconazole

2002

Other Studies

98 other study(ies) available for triazoles and Acute Liver Injury, Drug-Induced

ArticleYear
Permeabilized Cryopreserved Human Hepatocytes as an Exogenous Metabolic System in a Novel Metabolism-Dependent Cytotoxicity Assay for the Evaluation of Metabolic Activation and Detoxification of Drugs Associated with Drug-Induced Liver Injuries: Results w
    Drug metabolism and disposition: the biological fate of chemicals, 2022, Volume: 50, Issue:2

    Topics: Acetaminophen; Activation, Metabolic; Amiodarone; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Cytochrome P-450 Enzyme System; Glutathione; HEK293 Cells; Hepatocytes; Humans; Ketoconazole; Piperazines; Triazoles; Troglitazone

2022
Toxicological effects of acute prothioconazole and prothioconazole-desthio administration on liver in male Chinese lizards (Eremias argus).
    Chemosphere, 2022, Volume: 291, Issue:Pt 2

    Topics: Animals; Chemical and Drug Induced Liver Injury; Liver; Lizards; Male; Oxidative Stress; Triazoles

2022
Hepatic safety of the antifungal triazole agent posaconazole: characterization of adverse event reports in a manufacturer's safety database.
    Expert opinion on drug safety, 2022, Volume: 21, Issue:8

    Topics: Antifungal Agents; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Humans; Invasive Fungal Infections; Triazoles

2022
Comparison of Mold Active Triazoles as Primary Antifungal Prophylaxis in Patients With Newly Diagnosed Acute Myeloid Leukemia in the Era of Molecularly Targeted Therapies.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022, 10-29, Volume: 75, Issue:9

    Topics: Adult; Antifungal Agents; Azoles; Chemical and Drug Induced Liver Injury; Echinocandins; Fungi; Humans; Invasive Fungal Infections; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Retrospective Studies; Triazoles; Voriconazole

2022
Anastrozole and related glucuronic acid conjugate are electrophilic species.
    Xenobiotica; the fate of foreign compounds in biological systems, 2022, Volume: 52, Issue:4

    Topics: Anastrozole; Animals; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Female; Glucuronic Acid; Humans; Nitriles; Rats; Triazoles

2022
Exposure to high-performance benzotriazole ultraviolet stabilizers: Advance in toxicological effects, environmental behaviors and remediation mechanism using in-silica methods.
    Chemosphere, 2023, Volume: 315

    Topics: Chemical and Drug Induced Liver Injury; Humans; Risk Assessment; Triazoles; Ultraviolet Rays

2023
Highlight report: hepatotoxicity of triazole fungicides.
    Archives of toxicology, 2019, Volume: 93, Issue:10

    Topics: Cell Line; Chemical and Drug Induced Liver Injury; Fungicides, Industrial; Humans; Pregnane X Receptor; Triazoles

2019
Tebuconazole induced oxidative stress related hepatotoxicity in adult and larval zebrafish (Danio rerio).
    Chemosphere, 2020, Volume: 241

    Topics: Animals; Apoptosis; Catalase; Chemical and Drug Induced Liver Injury; Female; Fungicides, Industrial; Larva; Male; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Triazoles; Zebrafish

2020
Combined toxicity of imidacloprid, acetochlor, and tebuconazole to zebrafish (Danio rerio): acute toxicity and hepatotoxicity assessment.
    Environmental science and pollution research international, 2020, Volume: 27, Issue:10

    Topics: Animals; Catalase; Chemical and Drug Induced Liver Injury; Neonicotinoids; Nitro Compounds; Oxidative Stress; Superoxide Dismutase; Toluidines; Triazoles; Water Pollutants, Chemical; Zebrafish

2020
Efficacy of Allium sativum oil to alleviate tebuconazol-induced oxidative stress in the liver of adult rats.
    Cellular and molecular biology (Noisy-le-Grand, France), 2019, Dec-31, Volume: 65, Issue:8

    Topics: Animals; Antioxidants; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Flavonoids; Garlic; Glutathione; Glutathione Peroxidase; Liver; Male; Nitric Oxide; Oxidative Stress; Phenol; Plant Oils; Rats; Rats, Wistar; Superoxide Dismutase; Triazoles

2019
Liver Enzyme Elevations in
    The American journal of tropical medicine and hygiene, 2020, Volume: 103, Issue:1

    Topics: Acrylamides; Adamantane; Adult; Alanine Transaminase; Aminopyridines; Aminoquinolines; Antimalarials; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Erythrocyte Transfusion; Erythrocytes; Female; Ferrous Compounds; Healthy Volunteers; Heterocyclic Compounds, 4 or More Rings; Humans; Indoles; Isoquinolines; Malaria, Falciparum; Male; Metallocenes; Parasitemia; Peroxides; Piperazines; Plasmodium falciparum; Primaquine; Pyrimidines; Quinolines; Spiro Compounds; Sulfones; Triazoles; Young Adult

2020
Effects of difenoconazole on hepatotoxicity, lipid metabolism and gut microbiota in zebrafish (Danio rerio).
    Environmental pollution (Barking, Essex : 1987), 2020, Volume: 265, Issue:Pt A

    Topics: Animals; Chemical and Drug Induced Liver Injury; Dioxolanes; Gastrointestinal Microbiome; Larva; Lipid Metabolism; Triazoles; Water Pollutants, Chemical; Zebrafish

2020
In vivo evaluation of combination therapy targeting the isoprenoid biosynthetic pathway.
    Pharmacological research, 2021, Volume: 167

    Topics: Animals; Biosynthetic Pathways; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Diterpenes; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Therapy, Combination; Enzyme Inhibitors; Farnesyltranstransferase; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Mice, Inbred NOD; Mice, SCID; Pravastatin; Protein Prenylation; Terpenes; Triazoles; Xenograft Model Antitumor Assays

2021
Fungicide bromuconazole has the potential to induce hepatotoxicity at the physiological, metabolomic and transcriptomic levels in rats.
    Environmental pollution (Barking, Essex : 1987), 2021, Jul-01, Volume: 280

    Topics: Animals; Chemical and Drug Induced Liver Injury; Fungicides, Industrial; Furans; Liver; Male; Metabolomics; Rats; Transcriptome; Triazoles

2021
Metabolic Activation of Cholestatic Drug-Induced Bile Acid-Dependent Toxicity in Human Sandwich-Cultured Hepatocytes.
    Journal of pharmaceutical sciences, 2017, Volume: 106, Issue:9

    Topics: Activation, Metabolic; Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Bile Acids and Salts; Biological Transport; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cholestasis; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Hepatocytes; Humans; Male; Rats; Rats, Sprague-Dawley; Tolvaptan; Toxicity Tests; Triazoles

2017
Multicentre study of posaconazole delayed-release tablet serum level and association with hepatotoxicity and QTc prolongation.
    The Journal of antimicrobial chemotherapy, 2017, 08-01, Volume: 72, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Delayed-Action Preparations; Electrocardiography; Female; Humans; Liver Function Tests; Male; Middle Aged; Retrospective Studies; Serum; Tablets; Triazoles; Young Adult

2017
Bromuconazole-induced hepatotoxicity is accompanied by upregulation of PXR/CYP3A1 and downregulation of CAR/CYP2B1 gene expression.
    Toxicology mechanisms and methods, 2017, Volume: 27, Issue:7

    Topics: Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Constitutive Androstane Receptor; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Fungicides, Industrial; Furans; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Kidney; Lethal Dose 50; Lipid Peroxidation; Male; No-Observed-Adverse-Effect Level; Oxidative Stress; Pregnane X Receptor; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Renal Insufficiency; Triazoles

2017
Histopathological and proteomic responses in male Chinese rare minnow (Gobiocypris rarus) indicate hepatotoxicity following benzotriazole exposure.
    Environmental pollution (Barking, Essex : 1987), 2017, Volume: 229

    Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Cyprinidae; Liver; Male; Proteome; Proteomics; Triazoles; Water Pollutants, Chemical

2017
Modulatory effects of quercetin on liver histopathological, biochemical, hematological, oxidative stress and DNA alterations in rats exposed to graded doses of score 250.
    Toxicology mechanisms and methods, 2018, Volume: 28, Issue:1

    Topics: Animals; Antioxidants; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Dioxolanes; DNA Damage; Dose-Response Relationship, Drug; Fungicides, Industrial; Lethal Dose 50; Liver; Male; Nucleic Acid Denaturation; Oxidative Stress; Quercetin; Rats, Wistar; Triazoles

2018
Discovery of Potent and Selective Inhibitors of Cdc2-Like Kinase 1 (CLK1) as a New Class of Autophagy Inducers.
    Journal of medicinal chemistry, 2017, 07-27, Volume: 60, Issue:14

    Topics: Acetaminophen; Animals; Autophagy; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Models, Molecular; Protective Agents; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Quinolines; Stereoisomerism; Structure-Activity Relationship; Triazoles

2017
Hepatotoxic combination effects of three azole fungicides in a broad dose range.
    Archives of toxicology, 2018, Volume: 92, Issue:2

    Topics: Animals; Azoles; Chemical and Drug Induced Liver Injury; Epoxy Compounds; Fungicides, Industrial; Imidazoles; Liver; Male; Organ Size; Rats; Rats, Wistar; Toxicity Tests, Subchronic; Triazoles

2018
Bromodomain and Extraterminal (BET) Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration.
    The American journal of pathology, 2018, Volume: 188, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Azepines; Cell Proliferation; Chemical and Drug Induced Liver Injury; Hep G2 Cells; Hepatectomy; Hepatocytes; Humans; Liver Regeneration; Male; Mice; Mice, Inbred C57BL; Proteins; Signal Transduction; Triazoles; Zebrafish

2018
Tolerability of isavuconazole after posaconazole toxicity in leukaemia patients.
    Mycoses, 2019, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Leukemia; Liver Function Tests; Male; Middle Aged; Mycoses; Nitriles; Pyridines; Retrospective Studies; Triazoles; Young Adult

2019
Isavuconazole: Case Report and Pharmacokinetic Considerations.
    Chemotherapy, 2018, Volume: 63, Issue:5

    Topics: Administration, Oral; Antifungal Agents; Aspergillosis; Aspergillus flavus; Bronchoalveolar Lavage Fluid; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Drug Monitoring; Female; Half-Life; Humans; Immunocompromised Host; Nitriles; Pyridines; Tandem Mass Spectrometry; Triazoles; Voriconazole; Young Adult

2018
Organic semiconducting nanoprobe with redox-activatable NIR-II fluorescence for in vivo real-time monitoring of drug toxicity.
    Chemical communications (Cambridge, England), 2018, Dec-18, Volume: 55, Issue:1

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Fluorescent Dyes; Hep G2 Cells; Humans; Maleates; Mice; Nanostructures; Nitric Oxide; Oxidation-Reduction; Polystyrenes; Semiconductors; Spectroscopy, Near-Infrared; Triazoles

2018
Can Galactose Be Converted to Glucose in HepG2 Cells? Improving the
    Chemical research in toxicology, 2019, 08-19, Volume: 32, Issue:8

    Topics: Amiodarone; Benzbromarone; Chemical and Drug Induced Liver Injury; Galactose; Glucose; Hep G2 Cells; Humans; Metabolomics; Mitochondria, Liver; Piperazines; Triazoles; Troglitazone; Tumor Cells, Cultured

2019
A reduced grade of liver fibro-steatosis after raltegravir, maraviroc and fosamprenavir in an HIV/HCV co-infected patient with chronic hepatitis, cardiomyopathy, intolerance to nelfinavir and a marked increase of serum creatine phosphokinase levels probab
    The West Indian medical journal, 2012, Volume: 61, Issue:9

    Topics: Adult; Carbamates; Cardiomyopathies; Chemical and Drug Induced Liver Injury; Creatine Kinase; Cyclohexanes; Drug Substitution; Drug Therapy, Combination; Fatty Liver; Furans; Hepatitis C, Chronic; HIV Fusion Inhibitors; HIV Infections; HIV Integrase Inhibitors; HIV Protease Inhibitors; Humans; Liver Cirrhosis; Male; Maraviroc; Organophosphates; Pyrrolidinones; Raltegravir Potassium; Sulfonamides; Triazoles

2012
[Effectiveness of the correction of hepatotoxicity during combined chemoradiotherapy for cancer patients].
    Voprosy onkologii, 2013, Volume: 59, Issue:4

    Topics: Adult; Aged; Brain Neoplasms; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Chemoradiotherapy; Drug Administration Schedule; Female; Glioma; Humans; Infusions, Intravenous; Liver; Male; Middle Aged; Neoplasms; Protective Agents; Severity of Illness Index; Treatment Outcome; Triazoles

2013
Safety of deferasirox: a retrospective cohort study on the risks of gastrointestinal, liver and renal events.
    Pharmacoepidemiology and drug safety, 2014, Volume: 23, Issue:11

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Benzoates; Chemical and Drug Induced Liver Injury; Deferasirox; Female; Gastrointestinal Hemorrhage; Humans; Incidence; Iron Chelating Agents; Iron Overload; Male; Middle Aged; Necrosis; Proportional Hazards Models; Retrospective Studies; Taiwan; Triazoles

2014
Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma.
    Toxicology letters, 2014, Nov-04, Volume: 230, Issue:3

    Topics: Animals; Atropine; Captopril; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Flutamide; Lamivudine; Liver; Male; Mannitol; Metabolomics; Methotrexate; Neomycin; Oxidative Stress; Phenytoin; Piperazines; Propylthiouracil; Rats; Rats, Wistar; Streptomycin; Triazoles; Valproic Acid; Vancomycin; Zidovudine

2014
Hepatotoxic effects of (tri)azole fungicides in a broad dose range.
    Archives of toxicology, 2015, Volume: 89, Issue:11

    Topics: Animals; Chemical and Drug Induced Liver Injury; Constitutive Androstane Receptor; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Epoxy Compounds; Fungicides, Industrial; Gene Expression Regulation; Hepatocytes; Imidazoles; Male; Phenobarbital; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Triazoles

2015
An unusual cause of jaundice in a patient with breast cancer.
    BMJ case reports, 2014, Dec-24, Volume: 2014

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Biopsy; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Fatty Liver; Female; Humans; Jaundice; Liver; Liver Function Tests; Middle Aged; Nitriles; Triazoles

2014
Changes in Gut Microbiota May Be Early Signs of Liver Toxicity Induced by Epoxiconazole in Rats.
    Chemotherapy, 2014, Volume: 60, Issue:2

    Topics: Animals; Chemical and Drug Induced Liver Injury; Epoxy Compounds; Female; Gastrointestinal Tract; Microbiota; Rats; Rats, Sprague-Dawley; Triazoles

2014
The deferiprone and deferasirox combination is efficacious in iron overloaded patients with β-thalassemia major: A prospective, single center, open-label study.
    Pediatric blood & cancer, 2015, Volume: 62, Issue:9

    Topics: Adolescent; Adult; Benzoates; beta-Thalassemia; Chelation Therapy; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Deferasirox; Deferiprone; Drug Eruptions; Drug Therapy, Combination; Female; Ferritins; Gastrointestinal Diseases; Humans; Iron; Iron Chelating Agents; Iron Overload; Joint Diseases; Male; Prospective Studies; Proteinuria; Pyridones; Transfusion Reaction; Treatment Outcome; Triazoles; Young Adult

2015
Establishment of a mouse model for amiodarone-induced liver injury and analyses of its hepatotoxic mechanism.
    Journal of applied toxicology : JAT, 2016, Volume: 36, Issue:1

    Topics: Alanine Transaminase; Amiodarone; Animals; Chemical and Drug Induced Liver Injury; Dexamethasone; Gadolinium; Ketoconazole; Kupffer Cells; Male; Mice; Mice, Inbred BALB C; Models, Animal; Triazoles

2016
A case of anastrazole-related drug-induced autoimmune hepatitis.
    Clinical journal of gastroenterology, 2014, Volume: 7, Issue:5

    Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Chemical and Drug Induced Liver Injury; Female; Hepatitis, Autoimmune; Humans; Nitriles; Triazoles

2014
Oral Azole Antifungal Medications and Risk of Acute Liver Injury, Overall and by Chronic Liver Disease Status.
    The American journal of medicine, 2016, Volume: 129, Issue:3

    Topics: Administration, Oral; Adult; Antifungal Agents; California; Chemical and Drug Induced Liver Injury; Chronic Disease; Cohort Studies; Female; Humans; Liver Diseases; Liver Failure, Acute; Male; Middle Aged; Retrospective Studies; Transaminases; Triazoles

2016
Preliminary characterization of a murine model for 1-bromopropane neurotoxicity: Role of cytochrome P450.
    Toxicology letters, 2016, Sep-06, Volume: 258

    Topics: Animals; Atmosphere Exposure Chambers; Cerebral Cortex; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disease Models, Animal; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Hydrocarbons, Brominated; Injections, Intraperitoneal; Injections, Subcutaneous; Liver; Male; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Neurotoxicity Syndromes; Organ Size; ran GTP-Binding Protein; Solvents; Triazoles

2016
Transcriptome analyses demonstrate that Peroxisome Proliferator-Activated Receptor α (PPARα) activity of an ultraviolet absorber, 2-(2'-hydroxy-3',5'-di-tert-butylphenyl)benzotriazole, as possible mechanism of their toxicity and the gender differences.
    The Journal of toxicological sciences, 2016, Volume: 41, Issue:5

    Topics: Animals; Chemical and Drug Induced Liver Injury; Computational Biology; Databases, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Developmental; Liver; Male; Oligonucleotide Array Sequence Analysis; PPAR alpha; Rats, Sprague-Dawley; RNA, Messenger; Sex Factors; Time Factors; Triazoles

2016
Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice.
    Archives of toxicology, 2017, Volume: 91, Issue:8

    Topics: Animals; Chemical and Drug Induced Liver Injury; Constitutive Androstane Receptor; Dose-Response Relationship, Drug; Fungicides, Industrial; Gene Expression Regulation; Hepatocytes; Humans; Imidazoles; Male; Mice; Mice, Inbred C57BL; Phenobarbital; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Triazoles; Up-Regulation

2017
Solithromycin rejection chills antibiotic sector.
    Nature biotechnology, 2017, 03-07, Volume: 35, Issue:3

    Topics: Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Humans; Macrolides; Triazoles; United States; United States Food and Drug Administration

2017
Mode of action for reproductive and hepatic toxicity inferred from a genomic study of triazole antifungals.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 110, Issue:2

    Topics: Aging; Animals; Antifungal Agents; Chemical and Drug Induced Liver Injury; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Gestational Age; Infertility, Male; Liver; Liver Diseases; Male; Nitriles; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; Reproduction; Testis; Testosterone; Triazoles

2009
Hepatic safety of voriconazole after allogeneic hematopoietic stem cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2010, Volume: 16, Issue:1

    Topics: Adult; Antifungal Agents; Chemical and Drug Induced Liver Injury; Child; Cohort Studies; Drug Monitoring; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Liver; Liver Function Tests; Lymphocyte Depletion; Male; Opportunistic Infections; Pyrimidines; Retrospective Studies; Risk Factors; Statistics as Topic; T-Lymphocytes; Triazoles; Voriconazole

2010
Posaconazole prophylaxis during induction therapy of patients with acute lymphoblastic leukaemia.
    Mycoses, 2011, Volume: 54, Issue:4

    Topics: Adult; Alanine Transaminase; Antifungal Agents; Aspartate Aminotransferases; Aspergillus; Bilirubin; Candida; Chemical and Drug Induced Liver Injury; Chemoprevention; Female; Humans; Liver Function Tests; Male; Mycoses; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Triazoles; Young Adult

2011
Letrozole induces hepatotoxicity without causing oxidative stress: the protective effect of melatonin.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2011, Volume: 27, Issue:4

    Topics: Animals; Antioxidants; Aromatase Inhibitors; Chemical and Drug Induced Liver Injury; Female; Letrozole; Liver; Melatonin; Nitriles; Oxidative Stress; Rats; Rats, Sprague-Dawley; Triazoles

2011
Voriconazole-associated salt-losing nephropathy.
    Clinical and experimental nephrology, 2010, Volume: 14, Issue:4

    Topics: Aged; Antifungal Agents; Biomarkers; Chemical and Drug Induced Liver Injury; Fluid Therapy; Humans; Hyponatremia; Kidney Diseases; Liver; Male; Neurophysins; Protein Precursors; Pyrimidines; Renin; Sodium; Sodium Chloride; Time Factors; Treatment Outcome; Triazoles; Vasopressins; Voriconazole; Water-Electrolyte Balance

2010
Deferasirox induced liver injury in haemochromatosis.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2010, Volume: 20, Issue:8

    Topics: Benzoates; Chemical and Drug Induced Liver Injury; Deferasirox; Female; Hemochromatosis; Humans; Iron Chelating Agents; Middle Aged; Triazoles

2010
Ticlopidine-induced hepatotoxicity in a GSH-depleted rat model.
    Archives of toxicology, 2011, Volume: 85, Issue:4

    Topics: Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Glutathione; Platelet Aggregation Inhibitors; Protein Binding; Rats; Ticlopidine; Triazoles

2011
Management of voriconazole hepatotoxicity in a lung transplant patient.
    Transplant infectious disease : an official journal of the Transplantation Society, 2011, Volume: 13, Issue:3

    Topics: Alanine Transaminase; Antifungal Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Lung Transplantation; Middle Aged; Pulmonary Aspergillosis; Pyrimidines; Treatment Outcome; Triazoles; Voriconazole

2011
Propiconazole induces alterations in the hepatic metabolome of mice: relevance to propiconazole-induced hepatocarcinogenesis.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 120, Issue:2

    Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Fungicides, Industrial; Liver; Male; Metabolome; Mice; Mice, Inbred Strains; Molecular Structure; Organ Size; Triazoles

2011
A case of drug-induced hepatic injury associated with sitagliptin.
    Internal medicine (Tokyo, Japan), 2011, Volume: 50, Issue:9

    Topics: Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Humans; Hypoglycemic Agents; Jaundice; Liver; Male; Microscopy, Electron, Transmission; Middle Aged; Pyrazines; Sitagliptin Phosphate; Triazoles

2011
Deferasirox protects against iron-induced hepatic injury in Mongolian gerbil.
    Translational research : the journal of laboratory and clinical medicine, 2011, Volume: 157, Issue:6

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Benzoates; Caspase 3; Chemical and Drug Induced Liver Injury; Deferasirox; Disease Models, Animal; DNA Fragmentation; Ferritins; Gerbillinae; Iron Chelating Agents; Iron Overload; Iron-Dextran Complex; Male; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Translational Research, Biomedical; Triazoles

2011
Deferasirox induced liver injury in haemochromatosis.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2011, Volume: 21, Issue:11

    Topics: Administration, Oral; Benzoates; Chemical and Drug Induced Liver Injury; Deferasirox; Diagnosis, Differential; Dose-Response Relationship, Drug; Female; Hemochromatosis; Humans; Iron Chelating Agents; Middle Aged; Triazoles

2011
Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzoquinones; Blotting, Western; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Crystallography, X-Ray; Female; Heart; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; K562 Cells; Lactams, Macrocyclic; Male; Mice; Mice, Nude; Mice, SCID; Neoplasms; Rabbits; Rats; Rats, Sprague-Dawley; Triazoles; Xenograft Model Antitumor Assays

2012
The hepatocarcinogenic conazoles: cyproconazole, epoxiconazole, and propiconazole induce a common set of toxicological and transcriptional responses.
    Toxicological sciences : an official journal of the Society of Toxicology, 2012, Volume: 127, Issue:1

    Topics: Administration, Oral; Animals; Carcinogens; Cell Proliferation; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Epoxy Compounds; Fungicides, Industrial; Gene Expression Regulation, Neoplastic; Hepatocytes; Liver; Male; Mice; Mice, Inbred Strains; Oligonucleotide Array Sequence Analysis; Transforming Growth Factor alpha; Triazoles

2012
Severe hepatotoxicity and acute renal failure caused by diniconazole.
    Clinics and research in hepatology and gastroenterology, 2012, Volume: 36, Issue:5

    Topics: Acute Kidney Injury; Chemical and Drug Induced Liver Injury; Humans; Male; Middle Aged; Severity of Illness Index; Triazoles

2012
[Quantitative evaluation method of the informational value of initial symptoms based on Bayesian theory].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2012, Volume: 132, Issue:6

    Topics: Antifungal Agents; Bayes Theorem; Chemical and Drug Induced Liver Injury; Drug Information Services; Drug-Related Side Effects and Adverse Reactions; Exanthema; Humans; Pharmacists; Probability; Pyrimidines; Symptom Assessment; Triazoles; Voriconazole

2012
Mouse precision-cut liver slices as an ex vivo model to study idiosyncratic drug-induced liver injury.
    Chemical research in toxicology, 2012, Sep-17, Volume: 25, Issue:9

    Topics: Animals; Benzodiazepines; Biomarkers; Carbamazepine; Cell Survival; Chemical and Drug Induced Liver Injury; Chemokines; Chromans; Clozapine; Cytokines; Diclofenac; Drug Synergism; Female; Glutathione; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; In Vitro Techniques; Ketoconazole; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Nitrogen Oxides; Olanzapine; Pyrimidines; Thiazolidinediones; Triazoles; Troglitazone; Voriconazole

2012
Real-time concurrent monitoring of apoptosis, cytosolic calcium, and mitochondria permeability transition for hypermulticolor high-content screening of drug-induced mitochondrial dysfunction-mediated hepatotoxicity.
    Toxicology letters, 2012, Oct-17, Volume: 214, Issue:2

    Topics: Apoptosis; Benzophenones; Calcium; Caspase 3; Chemical and Drug Induced Liver Injury; Chromans; Hep G2 Cells; Humans; Image Processing, Computer-Assisted; Imidazoles; Liver; Microscopy, Fluorescence; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nitrophenols; Piperazines; Thiazolidinediones; Tolcapone; Triazoles; Troglitazone

2012
Voriconazole hepatotoxicity in severe liver dysfunction.
    The Journal of infection, 2013, Volume: 66, Issue:1

    Topics: Adult; Aged; Amphotericin B; Analysis of Variance; Antifungal Agents; Aspergillosis; Chemical and Drug Induced Liver Injury; Cohort Studies; Female; Humans; Liver; Liver Function Tests; Male; Middle Aged; Observation; Pyrimidines; Triazoles; Voriconazole

2013
[Rizatriptan-induced liver toxicity. Report of a case].
    Gastroenterologia y hepatologia, 2013, Volume: 36, Issue:4

    Topics: Adolescent; Chemical and Drug Induced Liver Injury; Female; Humans; Immune Complex Diseases; Jaundice, Obstructive; Migraine Disorders; Serotonin Receptor Agonists; Time Factors; Triazoles; Tryptamines

2013
[Toxic hepatitis after intake of raspberries].
    Medicina clinica, 2013, Jul-21, Volume: 141, Issue:2

    Topics: Chemical and Drug Induced Liver Injury; Food Contamination; Foodborne Diseases; Fruit; Fungicides, Industrial; Humans; Ivermectin; Male; Middle Aged; Pesticide Residues; Pyrethrins; Rosaceae; Triazoles

2013
Implication of hepatic transporters (MDR1 and MRP2) in inflammation-associated idiosyncratic drug-induced hepatotoxicity investigated by microvolume cytometry.
    Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2013, Volume: 83, Issue:4

    Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; Biological Transport; Chemical and Drug Induced Liver Injury; Flow Cytometry; Fluoroquinolones; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Inflammation; Ketolides; Lipopolysaccharides; Liver; Naphthyridines; Piperazines; Sulfonamides; Triazoles; Tumor Necrosis Factor-alpha; Xenobiotics

2013
[Acute liver failure in nefazodone therapy? A case report].
    Der Nervenarzt, 2002, Volume: 73, Issue:7

    Topics: Antidepressive Agents; Chemical and Drug Induced Liver Injury; Depressive Disorder; Fatal Outcome; Humans; Liver Failure, Acute; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Piperazines; Recurrence; Triazoles

2002
Withdrawing drugs: nefazodone, the start of the latest saga.
    Lancet (London, England), 2003, Apr-12, Volume: 361, Issue:9365

    Topics: Antidepressive Agents, Second-Generation; Chemical and Drug Induced Liver Injury; Drug Approval; Drug Monitoring; Humans; Piperazines; Product Surveillance, Postmarketing; Triazoles

2003
Hepatic injury and pancreatitis during treatment with serotonin reuptake inhibitors: data from the World Health Organization (WHO) database of adverse drug reactions.
    International clinical psychopharmacology, 2003, Volume: 18, Issue:3

    Topics: Adverse Drug Reaction Reporting Systems; Bayes Theorem; Chemical and Drug Induced Liver Injury; Cyclohexanols; Databases, Factual; Humans; Neural Networks, Computer; Pancreatitis; Piperazines; Selective Serotonin Reuptake Inhibitors; Triazoles; Venlafaxine Hydrochloride; World Health Organization

2003
Nefazodone (Serzone) withdrawn because of hepatotoxicity.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2003, Nov-25, Volume: 169, Issue:11

    Topics: Antidepressive Agents, Second-Generation; Chemical and Drug Induced Liver Injury; Humans; Jaundice; Liver; Necrosis; Piperazines; Triazoles

2003
The CYP inhibitor 1-aminobenzotriazole does not prevent oxidative stress associated with alcohol-induced liver injury in rats and mice.
    Free radical biology & medicine, 2003, Dec-15, Volume: 35, Issue:12

    Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Electron Spin Resonance Spectroscopy; Enzyme Induction; Enzyme Inhibitors; Ethanol; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Rats; Rats, Wistar; RNA, Messenger; Triazoles

2003
[Withdrawal of a drug from the market for safety reasons: process and communication].
    Praxis, 2004, May-05, Volume: 93, Issue:19

    Topics: Adverse Drug Reaction Reporting Systems; Antidepressive Agents, Second-Generation; Attitude of Health Personnel; Chemical and Drug Induced Liver Injury; Communication; Drug Industry; Drug Information Services; Drug-Related Side Effects and Adverse Reactions; Humans; Interprofessional Relations; Piperazines; Switzerland; Triazoles

2004
Iron chelation therapy.
    Current hematology reports, 2005, Volume: 4, Issue:2

    Topics: Administration, Oral; Benzoates; beta-Thalassemia; Chelation Therapy; Chemical and Drug Induced Liver Injury; Deferasirox; Deferiprone; Deferoxamine; Drug Therapy, Combination; Humans; Infusions, Intravenous; Iron Chelating Agents; Iron Overload; Isoniazid; Pyridones; Pyridoxal; Survival; Triazoles

2005
Investigation of the potential relationships between plasma voriconazole concentrations and visual adverse events or liver function test abnormalities.
    Journal of clinical pharmacology, 2006, Volume: 46, Issue:2

    Topics: Alanine Transaminase; Alkaline Phosphatase; Antifungal Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cohort Studies; Female; Humans; Liver Function Tests; Male; Pyrimidines; Regression Analysis; Retrospective Studies; Risk Assessment; ROC Curve; Triazoles; Vision Disorders; Voriconazole

2006
Medical management of depression.
    The New England journal of medicine, 2006, Feb-09, Volume: 354, Issue:6

    Topics: Chemical and Drug Induced Liver Injury; Depressive Disorder; Duloxetine Hydrochloride; Humans; Liver Function Tests; Piperazines; Selective Serotonin Reuptake Inhibitors; Thiophenes; Triazoles

2006
Primary hepatic invasive aspergillosis with progression after rituximab therapy for a post transplantation lymphoproliferative disorder.
    Annals of hematology, 2006, Volume: 85, Issue:9

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antifungal Agents; Antineoplastic Agents; Aspergillosis; Chemical and Drug Induced Liver Injury; Fatal Outcome; Female; Galactose; Graft vs Host Disease; Humans; Liver Diseases; Lymphoproliferative Disorders; Mannans; Middle Aged; Pyrimidines; Rituximab; Splenic Diseases; Stem Cell Transplantation; Transplantation, Homologous; Triazoles; Voriconazole

2006
Anastrozole-induced hepatotoxicity.
    European journal of gastroenterology & hepatology, 2006, Volume: 18, Issue:11

    Topics: Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Lobular; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Diseases; Liver Function Tests; Nausea; Nitriles; Triazoles

2006
Liver toxicity after treatment with gefitinib and anastrozole: drug-drug interactions through cytochrome p450?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Dec-10, Volume: 24, Issue:35

    Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Gefitinib; Humans; Isoenzymes; Lymphatic Metastasis; Middle Aged; Nitriles; Quinazolines; Triazoles

2006
Severe acute hepatitis in a patient treated with anastrozole.
    Lancet (London, England), 2007, Jan-06, Volume: 369, Issue:9555

    Topics: Anastrozole; Aromatase Inhibitors; Chemical and Drug Induced Liver Injury; Fatal Outcome; Female; Humans; Middle Aged; Nitriles; Triazoles

2007
Voriconazole: serious adverse effects and interactions.
    Prescrire international, 2007, Volume: 16, Issue:87

    Topics: Adult; Antifungal Agents; Chemical and Drug Induced Liver Injury; Child; Drug Interactions; France; Heart Diseases; Humans; Mental Disorders; Pyrimidines; Skin Diseases; Triazoles; Vision Disorders

2007
Toxicogenomic study of triazole fungicides and perfluoroalkyl acids in rat livers predicts toxicity and categorizes chemicals based on mechanisms of toxicity.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 97, Issue:2

    Topics: Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Fluorocarbons; Fungicides, Industrial; Hormones; Liver; Male; Oligonucleotide Array Sequence Analysis; Organ Size; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Testosterone; Thyroid Hormones; Triazoles; Weight Gain

2007
Posaconazole prophylaxis in hematologic cancer.
    The New England journal of medicine, 2007, May-24, Volume: 356, Issue:21

    Topics: Antifungal Agents; Bilirubin; Chemical and Drug Induced Liver Injury; Fluconazole; Graft vs Host Disease; Humans; Liver Diseases; Mycoses; Transaminases; Triazoles

2007
Lack of cross-hepatotoxicity between voriconazole and posaconazole.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Sep-15, Volume: 45, Issue:6

    Topics: Aged; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Chemical and Drug Induced Liver Injury; Humans; Pyrimidines; Triazoles; Voriconazole

2007
Hepatotoxicity of oral and intravenous voriconazole in relation to cytochrome P450 polymorphisms.
    The Journal of antimicrobial chemotherapy, 2007, Volume: 60, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Female; Genetic Predisposition to Disease; Humans; Injections, Intravenous; Liver; Male; Middle Aged; Polymorphism, Genetic; Pyrimidines; Retrospective Studies; Triazoles; Voriconazole

2007
Non-carboxylic analogues of naproxen: design, synthesis, and pharmacological evaluation of some 1,3,4-oxadiazole/thiadiazole and 1,2,4-triazole derivatives.
    Archiv der Pharmazie, 2007, Volume: 340, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Drug Design; Edema; Liver; Liver Function Tests; Male; Mice; Molecular Structure; Naproxen; Oxadiazoles; Pain; Rats; Stomach Ulcer; Thiadiazoles; Triazoles

2007
(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(1-methyl-1h-1,2,4-triazol-5-yl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid (BMS-644950): a rationally designed orally efficacious 3-hydroxy-3-methylglutaryl coenzyme-a reductase inhibitor with
    Journal of medicinal chemistry, 2008, May-08, Volume: 51, Issue:9

    Topics: Administration, Oral; Animals; Biological Availability; Chemical and Drug Induced Liver Injury; Cholesterol; Crystallography, X-Ray; Dogs; Female; Guinea Pigs; Haplorhini; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Liver; Models, Molecular; Muscle Cells; Pyrimidines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Triazoles

2008
Role of platelet-activating factor in pathogenesis of galactosamine-lipopolysaccharide-induced liver injury.
    Digestive diseases and sciences, 1996, Volume: 41, Issue:5

    Topics: Animals; Azepines; Cell Adhesion; Cells, Cultured; Chemical and Drug Induced Liver Injury; Endothelium; Escherichia coli; Galactosamine; Lipopolysaccharides; Liver; Male; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Triazoles; Tumor Necrosis Factor-alpha

1996
Neither platelet activating factor nor leukotrienes are critical mediators of liver injury after lipopolysaccharide administration.
    Toxicology, 1997, Sep-05, Volume: 121, Issue:3

    Topics: Administration, Oral; Alanine Transaminase; Animals; Azepines; Blood Platelets; Chemical and Drug Induced Liver Injury; Female; Fibrinogen; Hydroxyurea; Injections, Intraperitoneal; Injections, Intravenous; Leukotrienes; Lipopolysaccharides; Lipoxygenase Inhibitors; Liver; Liver Diseases; Necrosis; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thrombocytopenia; Triazoles

1997
Adverse effect of nefazodone: hepatitis.
    The Medical journal of Australia, 1999, May-03, Volume: 170, Issue:9

    Topics: Adult; Antidepressive Agents, Second-Generation; Chemical and Drug Induced Liver Injury; Depression; Humans; Male; Phobic Disorders; Piperazines; Triazoles

1999
Reversible nefazodone-induced liver failure.
    Digestive diseases and sciences, 2000, Volume: 45, Issue:5

    Topics: Antidepressive Agents, Second-Generation; Biopsy; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Female; Humans; Liver; Liver Cirrhosis, Alcoholic; Liver Failure; Middle Aged; Piperazines; Triazoles

2000
Hepatoprotection by dimethyl sulfoxide. III. Role of inhibition of the bioactivation and covalent bonding of chloroform.
    Toxicology and applied pharmacology, 2000, Jul-15, Volume: 166, Issue:2

    Topics: Alanine Transaminase; Allyl Compounds; Animals; Binding Sites; Chemical and Drug Induced Liver Injury; Chloroform; Cytochrome P-450 CYP2E1 Inhibitors; Dimethyl Sulfoxide; Enzyme Inhibitors; Free Radical Scavengers; Liver; Male; Rats; Rats, Sprague-Dawley; Sulfides; Time Factors; Triazoles

2000
Hepatotoxicity associated with the new antidepressants.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:2

    Topics: Adult; Aged; Antidepressive Agents; Chemical and Drug Induced Liver Injury; Depressive Disorder; Drug Monitoring; Female; Humans; Incidence; Liver Diseases; Piperazines; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Triazoles

2002
From the Food and Drug Administration.
    JAMA, 2002, Mar-06, Volume: 287, Issue:9

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Second-Generation; Antineoplastic Agents; Arthritis, Psoriatic; Benzamides; Chemical and Drug Induced Liver Injury; Cyclohexanones; Enzyme Inhibitors; Etanercept; Gastrointestinal Neoplasms; Humans; Imatinib Mesylate; Immunoglobulin G; Infant; Liver Failure; Nitrobenzoates; Orphan Drug Production; Piperazines; Pyrimidines; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Triazoles; Tyrosinemias; United States; United States Food and Drug Administration

2002
Hepatic adverse reactions associated with nefazodone.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2002, Volume: 47, Issue:4

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Antidepressive Agents, Second-Generation; Canada; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Liver Function Tests; Male; Middle Aged; Piperazines; Triazoles

2002
Effects of inflammation on peroxisomal enzyme activities, catalase synthesis, and lipid metabolism.
    Laboratory investigation; a journal of technical methods and pathology, 1977, Volume: 37, Issue:5

    Topics: Alcohol Oxidoreductases; Allylisopropylacetamide; Animals; Catalase; Chemical and Drug Induced Liver Injury; D-Amino-Acid Oxidase; Fatty Acids; Inflammation; Liver; Male; Microbodies; Nafenopin; Organoids; Oxidoreductases; Rats; Triazoles; Turpentine; Urate Oxidase

1977
The hepatotoxicity of 3-amino-1,2,4-triazole and carbon disulphide in phenobarbitone-treated starved rats.
    Toxicology, 1978, Volume: 9, Issue:1-2

    Topics: Alanine Transaminase; Amitrole; Animals; Carbon Disulfide; Chemical and Drug Induced Liver Injury; Liver; Male; Phenobarbital; Rats; Starvation; Time Factors; Triazoles

1978
Effect of 3-amino-1,2,4-triazole on carbon tetrachloride-induced necrosis.
    Chemical & pharmaceutical bulletin, 1977, Volume: 25, Issue:8

    Topics: Alanine Transaminase; Amitrole; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Depression, Chemical; Liver Diseases; Male; Necrosis; Rats; Triazoles

1977
[Protective effect of a platelet activating factor antagonist in experimental liver injury].
    Zhonghua yi xue za zhi, 1990, Volume: 70, Issue:7

    Topics: Animals; Azepines; Chemical and Drug Induced Liver Injury; Endotoxins; Galactosamine; Liver; Malondialdehyde; Peroxidase; Platelet Activating Factor; Rats; Rats, Inbred Strains; Superoxide Dismutase; Triazoles

1990
Modifying effect of 3-amino-1,2,4-triazole on phenobarbital-induced changes in rat liver.
    Experimental and molecular pathology, 1972, Volume: 16, Issue:2

    Topics: Amitrole; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochromes; Drug Antagonism; Endoplasmic Reticulum; Enzyme Induction; Herbicides; Liver; Liver Diseases; Male; Microscopy, Electron; Microsomes, Liver; Necrosis; Paralysis; Phenobarbital; Rats; Triazoles; Zoxazolamine

1972
[Toxicology of chemical sweetening agents].
    Wiener medizinische Wochenschrift (1946), 1971, Jun-19, Volume: 121, Issue:25

    Topics: Abnormalities, Drug-Induced; Animals; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Chromosome Aberrations; Chromosome Disorders; Cyclamates; Cyclohexylamines; Depression, Chemical; Esters; Guinea Pigs; Humans; Kidney Diseases; Mice; Pancreatic Diseases; Peptides; Phenylalanine; Photosensitivity Disorders; Rats; Saccharin; Sweetening Agents; Tolbutamide; Triazoles; Urinary Bladder Neoplasms

1971
[A comparative evaluation of the toxic and possible carcinogenic effect of benzotriazol and phenidon].
    Gigiena truda i professional'nye zabolevaniia, 1970, Volume: 14, Issue:3

    Topics: Animals; Carcinogens; Chemical and Drug Induced Liver Injury; Female; Fibroma; Leukemia, Experimental; Lung Diseases; Lung Neoplasms; Male; Mesentery; Mice; Neoplasms, Experimental; Rats; Sarcoma, Experimental; Splenic Diseases; Triazoles

1970