triazoles has been researched along with Acute Liver Injury, Drug-Induced in 113 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (5.31) | 18.7374 |
1990's | 5 (4.42) | 18.2507 |
2000's | 30 (26.55) | 29.6817 |
2010's | 59 (52.21) | 24.3611 |
2020's | 13 (11.50) | 2.80 |
Authors | Studies |
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Li, AP; Wei, H | 1 |
Chang, J; Hao, W; Li, J; Pan, Y; Xie, Y | 1 |
Leong, R; O'Flynn, R; Straus, W; Waskin, H; Zhou, YP | 1 |
DiNardo, CD; DiPippo, AJ; Jiang, Y; Kadia, T; Kontoyiannis, DP; Maiti, A; Montalban-Bravo, G; Rausch, CR; Ravandi, F | 1 |
Chen, Y; Ding, S; Liu, S; Peng, Y; Zheng, J | 1 |
Chen, X; Li, Y; Xue, J; Zhao, Y | 1 |
Albrecht, W | 1 |
Chen, L; Coffin, S; Gui, W; Jiang, Y; Li, S; Qiao, K; Sun, Q; Zhu, G | 1 |
Chang, Y; Jiang, H; Mao, L; Zhang, L; Zhang, Y | 1 |
Berrouague, S; Boumendjel, A; Boumendjel, M; Khaldi, T; Messarah, M; Rouag, M; Taibi, F | 1 |
Abd Eldaim, MA; Abdallah, AEM; Abdel-Daim, MM; Abdelaziz, SAM; Abdul Rashid, S; Abdullah, AS; Abdullah, LC; Abramson, MJ; Ahmed, HB; Ahmed, MM; Ahn, YC; Alexander, DC; Ando, T; Angelone, AM; Anglani, F; Ap, Y; Arthanari, SK; Axelrad, C; Bai, S; Bakonyi, P; Barnes, E; Beckmann, NA; Bélafi-Bakó, K; Bennett, CM; Bestha, RM; Bitsch, RG; Bradley, CA; Bu, Y; Calò, LA; Cañedo-Villaroya, E; Carlson, L; Caruso, S; Casado-Flores, J; Ceol, M; Cesarino, I; Chen, IL; Chen, R; Chen, X; Chilvers, MI; Cho, WK; Choong, TSY; Conceição-Neto, N; Culver, EL; Dai, X; de Lama Caro-Patón, G; De Rosa, I; Del Prete, D; Dharmage, SC; Dimitriadis, E; Dittakavi, S; Dobrowolski, JC; Edin, S; Elgarawany, GE; Emam, HE; Emmens, RW; Erbas, B; Erwich, JJHM; Farghali, M; Feng, L; Funston, RN; Gabler, NK; Gale, P; Ganesh, M; Gao, J; Gao, L; Gao, X; García-Salido, A; Gatto, R; Gautam, S; Ge, C; Ghogomu, SM; Gianesello, L; Gonçales, VR; Gooch, JL; Gooding, JJ; Gourley, GG; Gu, H; Gu, X; Gu, Z; Guerreri, M; Guillén, M; Hazzaa, SM; Heylen, E; Hicks, R; Hong, X; Hoshi, M; Hu, B; Hu, LX; Hu, R; Hu, S; Huang, J; Huang, K; Hubbard, WB; Hui, J; Hwang, NY; Iannacci, J; Ianus, A; Iglesias-Bouzas, MI; Ihara, I; Iwasaki, M; Jaeger, S; Kandel, YR; Karpińska, G; Kim, HK; Klopfenstein, TJ; Knorr, D; Koók, L; Kotb, S; Kruithof, S; Larsson, P; Laurence, C; Leng, J; Li, H; Li, J; Li, Q; Li, S; Li, X; Li, Z; Lian, J; Liang, JX; Liang, X; Lighaam, LC; Lin, CW; Lin, HC; Lin, J; Ling, A; Liu, J; Liu, P; Liu, YS; Ljuslinder, I; Lo, GH; Lodge, CJ; Löfgren-Burström, A; Lowe, AJ; Lu, M; Lu, N; Lucero-Prisno, DE; Luebbe, KM; Luo, X; Ma, Z; Maes, P; Makuch, M; Malekbala, MR; Mao, Z; Martínez-Romera, I; Marzo, G; Mathew, FM; Mattei, A; Matthijnssens, J; Mayumi, M; Morita, N; Mueller, DS; Mullangi, R; Mummolo, S; Murthi, P; Myte, R; Nabeshima, T; Nakamoto, K; Nehdi, IA; Nemestóthy, N; Niessen, HWM; Noh, JM; Nota, A; Nunes, D; Oh, D; Öhlund, D; Olsen, KM; Ono, H; Osawa, Y; Palmqvist, R; Palombo, M; Park, M; Patience, JF; Peng, Y; Perng, DS; Persano, A; Priante, G; Prince, SJ; Pulipati, S; Pyo, H; Qiu, X; Quan, J; Quaranta, F; Quinzi, V; Rademacher, CJ; Rajaraman, G; Rashid, U; Rauch, JC; Rector, A; Remmerswaal, EBM; Ren, R; Rispens, T; Rocha, GS; Saad, NM; Saito, K; Salamova, A; Sarfaraz, K; Satoshi, A; Schnellmann, RG; Scholpa, NE; Schonhoff, M; Schwartz, KJ; Schwarze, M; Schweer, WP; Seiichi, Y; Serrano-González, A; Severino, J; Shemesh, N; Shi, ZQ; Shike, DW; Shim, YM; Siciliano, PA; Siebenrock, KA; Silva, MKL; Smith, DL; Soltani, S; Song, YM; Spry, ML; Stalker, LA; Stokes, RS; Sullivan, PG; Sun, JM; Sun, S; Svanes, C; Syo, K; Tai, CM; Takashima, S; Tashita, C; Taurino, A; Ten Berge, IJM; Tenuta, AU; Teo, SH; Tilley, RD; Trivedi, RK; Umetsu, K; Unger, PA; van Bruggen, R; van Ham, SM; Van Ranst, M; Vanitha, J; Vekaria, HJ; Venier, M; Venkateshwaran, K; Venkert, A; Vermeulen, E; Wan, C; Wang, H; Wang, N; Wang, P; Wang, T; Wang, X; Wang, Y; Wise, KA; Wolbink, GJ; Wu, J; Wu, P; Wu, S; Wu, Y; Xia, Q; Xin, W; Xiong, Q; Xu, H; Xu, P; Xue, S; Yamamoto, Y; Yamashiro, T; Yan, F; Yan, H; Yan, S; Yan, Y; Yang, JM; Yang, L; Yang, P; Ye, W; Yeh, JH; Yinda, CK; Ying, GG; Ying, L; Yoon, HG; Yu, H; Zainuddin, M; Zakkula, A; Zeller, M; Zeng, Y; Zha, J; Zhang, F; Zhang, H; Zhang, M; Zhang, Q; Zhang, S; Zhang, T; Zhang, Z; Zhao, C; Zhao, J; Zhao, Y; Zhong, Q; Zhu, J; Zingmark, C; Zo, JI; Zou, Y | 1 |
Akakpo, S; Chalon, S; Chughlay, MF; Csermak-Renner, K; Djeriou, E; Gaur, AH; Leboulleux, D; McCarthy, J; Odedra, A; Shanks, GD; Winnips, C | 1 |
Chen, L; Jiang, J; Liu, X; Lv, L; Wang, Q; Wu, S; Zhao, X | 1 |
Chhonker, Y; Haney, SL; Holstein, SA; Murry, DJ; Smith, LM; Talmon, G; Varney, ML | 1 |
Han, J; Ji, X; Qian, M; Wang, J; Wu, H; Wu, S; Xu, J; Zhang, H | 1 |
Adas, M; Bechman, K; Clarke, B; Galloway, J; Yates, M | 1 |
Aitken, SL; Brown, JE; Buege, MJ | 1 |
Bando, K; Ito, K; Nakagawa, T; Ogimura, E; Sekine, S; Tokizono, M | 1 |
Delacruz, J; Gedrimaite, Z; Han, Z; Hsu, M; Miceli, MH; Narayanan, PP; Paskovaty, A; Perissinotti, AJ; Pettit, NN; Pisano, J; Rivera, CG; Seo, SK; Steinbeck, J | 1 |
Abdelhadya, DH; El-Magd, MA; Elbialy, ZI; Saleh, AA | 1 |
Liang, X; Martyniuk, CJ; Wang, Z; Zha, J; Zhao, J | 1 |
Bkhairia, I; Ghozzi, H; Hakim, A; Harrabi, B; Jamoussi, K; Kallel, C; Kasmi, S; Marrakchi, R; Mnif, H; Nasri, M; Zeghal, K | 1 |
Chen, C; Chen, K; Huang, LY; Jin, XT; Li, LL; Lin, GF; Lu, GW; Sun, QZ; Wei, YQ; Xiang, R; Yang, SY; Yang, W; Zhang, G | 1 |
Geburek, I; Haider, W; Heise, T; Knebel, C; Marx-Stoelting, P; Niemann, L; Rieke, S; Schmidt, F | 1 |
Ko, S; Monga, SP; Poddar, M; Russell, JO; Saggi, HS; Shin, D; Singh, S | 1 |
DiPippo, AJ; Kontoyiannis, DP; Rausch, CR | 1 |
Girmenia, C; Goffredo, BM; Marchesi, F; Mengarelli, A; Menna, P; Minotti, G; Romano, A; Salvatorelli, E | 1 |
Fan, Q; Hu, W; Hu, X; Huang, W; Ji, Y; Li, X; Li, Y; Lu, X; Pei, F; Tang, Y; Wang, Z; Zhao, H | 1 |
Aslamkhan, AG; Gonzalez, R; Imredy, J; Kaczor, A; Kuhls, M; Lebron, J; Liaw, A; Liu, L; Mitra, K; Pearson, K; Ruth, M; Sistare, FD; Vu, H; Wei, C; Xu, Q; Yu, Y | 1 |
Lacombe, K; Surgers, L | 1 |
Barrette, S; Files, B; Habr, D; Minniti, CP; Torres, M; Vichinsky, E; Zhang, Y | 1 |
Degli Antoni, A; Ferrari, C; Fragola, V; Manfredi, R; Weimer, LE | 1 |
Korytova, LI; Masliukova, EA; Meshechkin, AV; Sokurenko, VP; Zhabina, RM | 1 |
Chou, HC; Hsiao, FY; Huang, WF; Tsai, YW | 1 |
Davis, K; Fabian, E; Greenhaw, J; Groeters, S; Herold, M; Kamp, H; Looser, R; Marxfeld, H; Mattes, W; Mellert, W; Moeller, N; Montoya-Parra, G; Prokoudine, A; Strauss, V; van Ravenzwaay, B; Walk, T | 1 |
Haider, W; Heise, T; Knebel, C; Kneuer, C; Marx-Stoelting, P; Niemann, L; Pfeil, R; Rieke, S; Schmidt, F | 1 |
Evans, A; Lacey, R | 1 |
Hachulla, E; Kahl, L; Layton, M; Machado, D; Patel, J; Schifano, L; Staumont-Sallé, D; van Vollenhoven, RF | 1 |
Gu, A; Huan, F; Jiang, Z; Liu, Q; Liu, W; Qu, J; Wang, Y; Xu, C | 1 |
Attri, SV; Bansal, D; Bhatia, P; Marwaha, RK; Totadri, S; Trehan, A | 1 |
Fukami, T; Nakajima, M; Oda, S; Takai, S; Tsuneyama, K; Yokoi, T | 1 |
Islam, MS; Lucas, R; Tanner, P; Wright, G | 1 |
Carbonari, DM; Corley, DA; Forde, KA; Goldberg, DS; Haynes, K; Lewis, JD; Lo Re, V; Marks, AR; Reddy, KR; Roy, JA; Schneider, JL; Sha, D; Strom, BL | 1 |
Isin, EM; Mettetal, JT; Ogese, MO; Thompson, RA; Williams, DP | 1 |
Chanda, S; Coronado, D; Del Rosso, J; Zane, LT | 1 |
Chang, J; Garner, CE; Huang, C; Ichihara, G; Ichihara, S; Ito, H; Kato, M; Sakurai, T; Toyokuni, S; Zhang, L; Zhang, X; Zong, C | 1 |
Ema, M; Hirata-Koizumi, M; Hirose, A; Ise, R; Kato, H; Matsuyama, T; Nishimaki-Mogami, T; Ono, A; Takahashi, M | 1 |
Groll, AH; Kyriakidis, I; Munchen, S; Tragiannidis, A | 1 |
Braeuning, A; Ganzenberg, K; Hammer, H; Knebel, C; Marx-Stoelting, P; Pötz, O; Rieke, S; Schmidt, F; Schwarz, M | 1 |
Owens, B | 1 |
Arribas López, JR | 1 |
Dix, DJ; Goetz, AK | 1 |
Amigues, I; Barker, J; Chung, D; Cohen, N; Jakubowski, A; Papanicolaou, GA; Plescia, C; Seo, SK | 1 |
Babatz, J; Ehninger, G; Illmer, T; Pursche, S; Schaich, M; Schuler, U; Stölzel, F | 1 |
Alçin, E; Aydin, M; Nacar, A; Oktar, S; Ozkan, OV; Oztürk, OH | 1 |
Inoue, T; Kakita, T; Matsuda, H; Mori, T; Nagatoya, K; Teranishi, J; Yamauchi, Y | 1 |
Aslam, N; Marsano-Obando, LS; Martin, A; Mettu, P | 1 |
Atsumi, R; Izumi, T; Nakazawa, T; Okazaki, O; Saji, H; Shimizu, S; Sudo, K | 1 |
Bedouch, P; Belaiche, S; Pison, C; Quetant, S; Roustit, M; Saint-Raymond, C | 1 |
Moore, T; Nesnow, S; Padgett, WT | 1 |
Jarque, I; Salavert, M | 1 |
Hibi, T; Kaneko, F; Motoori, T; Oda, M; Ohbu, M; Shimizu, Y; Tahara, K; Takeuchi, H; Toyoda-Akui, M; Yokomori, H | 1 |
Al-Rousan, RM; Blough, ER; Katta, A; Laurino, J; Rice, KM; Triest, WE; Walker, EM; Wu, M | 1 |
Imran, FS; Phatak, P | 1 |
Acquaviva, J; Barsoum, J; Blackman, RK; Du, Z; Foley, KP; Inoue, T; Koya, K; Ogawa, LS; Proia, DA; Sang, J; Sun, L; Tatsuta, N; Wada, Y; Ye, S; Ying, W; Zhou, D | 1 |
Hester, S; Moore, T; Murphy, L; Nesnow, S; Padgett, WT; Wood, CE | 1 |
Bayrak, A; Coskun, Y; Erarslan, E; Koç, H; Uflaz, B; Yüksel, I | 1 |
Ieda, M; Kobayashi, D; Ohshima, S; Yamamoto, M | 1 |
Chen, Y; Groothuis, GM; Hadi, M; Merema, MT; Starokozhko, V | 1 |
Eun, CJ; Han, E; Kim, JA; Song, JM; Tak, YK | 1 |
Auzinger, G; Bernal, W; Heneghan, MA; López, JC; Solís-Muñoz, P; Verma, A; Wendon, J; Willars, C | 1 |
Casas, M; Dalmau, B; Fernandez-Atutxa, A; Gil, M; Miquel, M; Sanchez-Delgado, J; Vergara, M | 1 |
Hidalgo-Castellón, AJ; Pérez, MA; Ramos-Clemente, JI | 1 |
Muller, CD; Peluso, J; Saab, L; Ubeaud-Sequier, G | 1 |
Ehrentraut, S; Gerbes, AL; Kapfhammer, HP; Rau, HG; Rothenhäusler, HB; Schirren, CA; Thiel, M | 1 |
Edwards, IR | 1 |
Bate, A; Hägg, S; Spigset, O | 1 |
Choi, S | 1 |
Arteel, GE; Bradford, BU; Connor, HD; Froh, M; Isayama, F; Kadiiska, MB; Koop, DR; Mason, RP; McKim, SE; Wheeler, MD | 1 |
Buclin, T; Genton, A | 1 |
Cabantchik, ZI; Hershko, CM; Konijn, AM; Link, GM | 1 |
Deresinski, S; Song, JC | 1 |
Brayshaw, N; Tan, K; Tomaszewski, K; Troke, P; Wood, N | 1 |
Ammar, H; Malani, AK | 1 |
Blijlevens, NM; Donnelly, JP; Klont, RR; van der Velden, WJ; Verweij, PE | 1 |
Bujanda, L; Piérola, A; Zapata, E; Zubiaurre, L | 1 |
Carlini, P; Ciccarese, M; Cognetti, F; Fabi, A; Felici, A; Ferretti, G; Milella, M; Nuzzo, C; Papaldo, P; Ruggeri, EM | 1 |
de la Cruz, L; Herrerias-Gutierrez, JM; Jiménez-Sáenz, M; Padron, JR; Romero-Vazquez, J | 1 |
Ayanoglu, E; Brennan, RJ; Corton, JC; Dix, DJ; Hu, W; Kavlock, RJ; Lau, C; Martin, MT; Ren, H; Wood, CR | 1 |
Krause, DS | 1 |
Foo, H; Gottlieb, T | 1 |
den Hollander, JG; Levin, MD; Rijnders, BJ; Sonneveld, P; van der Holt, B; van Schaik, RH; van Vliet, M | 1 |
Amir, M; Javed, SA; Kumar, H | 1 |
Vichinsky, E | 1 |
Ahmad, S; Barrish, JC; Bird, E; Bisaha, S; Blanar, MA; Chang, M; Chen, BC; Chen, X; Cuff, CA; Darienzo, CJ; Giancarli, M; Harrity, T; Huang, C; Janovitz, E; Kennedy, LJ; Li, T; Madsen, CS; Monshizadegan, H; Ngu, K; Nguyen-Tran, V; Reeves, RA; Robl, JA; Ryan, CS; Search, D; Setters, R; Sitkoff, D; Stein, PD; Yin, X; Zahler, R; Zhang, R; Zhao, R; Zhuang, S | 1 |
Gearhart, MO | 1 |
Han, K; Hashimoto, N; Hikiba, Y; Kawase, T; Komatsu, Y; Okano, K; Omata, M; Shiratori, Y; Yoshida, H | 1 |
Bailie, MB; Fink, GD; Pearson, JM; Roth, RA | 1 |
Roberts-Thompson, IC; Schrader, GD | 1 |
Eloubeidi, MA; Gaede, JT; Swaim, MW | 1 |
Begay, CK; Gandolfi, AJ; Lind, RC | 1 |
Anaissie, E; Arndt, C; Donowitz, G; Finberg, R; Fioritoni, G; Garber, G; Greenberg, R; Hadley, S; Laverdière, M; Lazarus, HM; Lee, J; Pappas, P; Perfect, J; Petersen, F; Raffalli, J; Reboli, A; Reinhardt, J; Schuster, M; Stiff, P; Walsh, TJ; Wingard, J; Winston, DJ; Yanovich, S | 1 |
Carvajal García-Pando, A; García del Pozo, J; Lucena, MI; Rueda de Castro, AM; Sánchez, AS; Velasco, MA | 1 |
Schwetz, BA | 1 |
Stewart, DE | 1 |
Ayala, E; Canonico, PG; Rill, W | 1 |
Butler, WH; Magos, L; Snowden, R | 1 |
Inatsu, Y; Ishii, H; Ninobe, S; Suga, T | 1 |
Zhang, F | 1 |
Johnson, EA; Stenger, RJ | 1 |
Göttinger, E | 1 |
Vasil'eva, NN | 1 |
12 review(s) available for triazoles and Acute Liver Injury, Drug-Induced
Article | Year |
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Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Amylose; Anaerobiosis; Animals; Anti-Bacterial Agents; Anura; Arginase; Arthritis, Rheumatoid; Asthma; Atmosphere; B-Lymphocytes; Basic Helix-Loop-Helix Transcription Factors; Bioelectric Energy Sources; Biofilms; Biofuels; Biomarkers; Biopolymers; Bioreactors; Brain; Brain Injuries, Traumatic; Breast Neoplasms; Calibration; Carbon Tetrachloride; Caspase 3; Catalysis; Catechin; Cations; Cattle; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Body; Cell Line, Tumor; Cell Plasticity; Chemical and Drug Induced Liver Injury; Chemistry Techniques, Synthetic; China; Chitosan; Chloride Channels; Chromatography, High Pressure Liquid; Chromosome Mapping; Cognition; Cognitive Dysfunction; Cohort Studies; Colitis, Ulcerative; Colloids; Coloring Agents; Congresses as Topic; Correlation of Data; Crystallization; Cyanoacrylates; Cyclohexane Monoterpenes; Cyprinidae; Cytochrome P-450 CYP1A1; Death, Sudden; Dent Disease; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Disease Progression; Disease Resistance; Disulfides; Drug Monitoring; Drug Stability; Ecotoxicology; Electricity; Electrodes; Endocytosis; Environmental Exposure; Environmental Monitoring; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal and Gastric Varices; Esters; Fagopyrum; Female; Ferrosoferric Oxide; Flame Retardants; Flavobacteriaceae; Flow Cytometry; Follow-Up Studies; Formoterol Fumarate; Fusarium; Garlic; Gastrointestinal Hemorrhage; Gene Expression; Genes, Plant; Genetic Markers; Glial Fibrillary Acidic Protein; Gliosis; Global Health; Glutathione Transferase; Glycine max; Gum Arabic; Hemostasis, Endoscopic; Hepatocytes; Hippocampus; Humans; Hydrogen-Ion Concentration; Illinois; Immunoglobulin G; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infant, Newborn; Infant, Small for Gestational Age; Injections, Intraperitoneal; Interleukin-4; Iowa; Iron; Ki-67 Antigen; Kidney; Kinetics; Kynurenine; Lakes; Levofloxacin; Lipid Peroxidation; Lipids; Liver; Liver Cirrhosis, Experimental; Magnetic Fields; Magnetic Iron Oxide Nanoparticles; Male; Manure; Maze Learning; Memory, Short-Term; Metal Nanoparticles; Metals, Heavy; Methane; Mice; Mice, Inbred C57BL; Mice, Knockout; Michigan; Microalgae; Microbial Consortia; Mitochondria; Models, Animal; Models, Chemical; Models, Neurological; Molecular Structure; Molecular Weight; Mutation; Myeloid-Derived Suppressor Cells; NADPH Oxidase 2; Neoplasm Recurrence, Local; Neurites; Neurons; Neuroprotective Agents; NF-kappa B; NIH 3T3 Cells; Nitric Oxide Synthase Type II; Nitrogen; Ohio; Ointments; Ontario; Organelle Biogenesis; Organophosphates; Organophosphorus Compounds; Oxidative Stress; Palladium; Particle Size; Pectins; Phenotype; Phytotherapy; Piperidines; Placenta; Plant Diseases; Plant Extracts; Polymers; Polymorphism, Genetic; Polyphenols; Powders; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Protein Kinase Inhibitors; Protein Structure, Secondary; Proteins; Pyridines; Pyrimidines; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; Recovery of Function; Recurrence; Reference Standards; Reference Values; Reproducibility of Results; Respiratory Function Tests; Retrospective Studies; Risk; Sensitivity and Specificity; Sewage; Signal Transduction; Sodium Glutamate; Soil; Solanum tuberosum; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spermatozoa; STAT3 Transcription Factor; Sulfamethoxazole; Tea; Temperature; Thermodynamics; Thrombin; Treatment Outcome; Triazoles; United States; Viscosity; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical; Water Purification; White Matter; Wisconsin; X-Ray Diffraction; Zea mays | 2013 |
The safety of JAK-1 inhibitors.
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Diverticular Diseases; Herpes Simplex; Herpes Zoster; Heterocyclic Compounds, 3-Ring; Humans; Immunocompromised Host; Infections; Intestinal Perforation; Janus Kinase 1; Janus Kinase Inhibitors; Latent Infection; Opportunistic Infections; Pyridines; Triazoles | 2021 |
Solithromycin: A novel ketolide antibiotic.
Topics: Animals; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Community-Acquired Infections; Drug Approval; Drug Resistance, Bacterial; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Pneumonia, Bacterial; Triazoles; United States; United States Food and Drug Administration | 2017 |
Hepatoxicity of new antiretrovirals: a systematic review.
Topics: Anti-Retroviral Agents; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cyclohexanes; Darunavir; Heterocyclic Compounds, 3-Ring; Humans; Maraviroc; Nitriles; Oxazines; Piperazines; Pyridazines; Pyridones; Pyrimidines; Pyrrolidinones; Quinolones; Raltegravir Potassium; Rilpivirine; Sulfonamides; Triazoles | 2013 |
Reactive Metabolites: Current and Emerging Risk and Hazard Assessments.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antidepressive Agents, Second-Generation; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Pharmaceutical Preparations; Piperazines; Risk Assessment; Triazoles | 2016 |
Antifungal agents for onychomycosis: new treatment strategies to improve safety.
Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chemical and Drug Induced Liver Injury; Ciclopirox; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Itraconazole; Naphthalenes; Onychomycosis; Pyridones; Terbinafine; Triazoles | 2016 |
Clinical hepatotoxicity associated with antifungal agents.
Topics: Amphotericin B; Animals; Antifungal Agents; Chemical and Drug Induced Liver Injury; Drug Interactions; Echinocandins; Humans; Invasive Fungal Infections; Liver Function Tests; Triazoles | 2017 |
[Secondary effects of treatment with maraviroc and other CCR5 antagonists. Potential impact of the CCR5 blocker].
Topics: Adult; Benzoates; CCR5 Receptor Antagonists; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Comorbidity; Cyclohexanes; Diketopiperazines; Disease Susceptibility; Drug Design; env Gene Products, Human Immunodeficiency Virus; HIV Fusion Inhibitors; HIV Infections; Homozygote; Humans; Hyperlipidemias; Incidence; Infections; Maraviroc; Membrane Fusion; Neoplasms; Piperazines; Receptors, CCR5; Sequence Deletion; Spiro Compounds; Triazoles; Virus Attachment; Virus Internalization | 2008 |
[Is micafungin useful in the prophylaxis of invasive fungal disease in hematological patients?].
Topics: Adult; Ambulatory Care; Antifungal Agents; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topic; Dose-Response Relationship, Drug; Echinocandins; Female; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Kidney Diseases; Lipopeptides; Male; Meta-Analysis as Topic; Micafungin; Mycoses; Postoperative Complications; Practice Guidelines as Topic; Triazoles | 2011 |
Hepatotoxicity of antifungal agents.
Topics: Allylamine; Animals; Antifungal Agents; Chemical and Drug Induced Liver Injury; Flucytosine; Humans; Imidazoles; Polyenes; Triazoles | 2005 |
Clinical application of deferasirox: practical patient management.
Topics: Administration, Oral; Adult; Benzoates; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topic; Contraindications; Creatinine; Deferasirox; Disease Management; Drug Eruptions; Gastrointestinal Diseases; Hematologic Diseases; Hemosiderosis; Humans; Iron; Iron Chelating Agents; Iron Overload; Kidney Diseases; Transfusion Reaction; Triazoles | 2008 |
Worsening of liver function with fluconazole and review of azole antifungal hepatotoxicity.
Topics: Administration, Oral; Alanine Transaminase; Aspartate Aminotransferases; Candidiasis; Chemical and Drug Induced Liver Injury; Female; Fluconazole; Hospitals, Teaching; Humans; Liver Diseases; Liver Function Tests; Middle Aged; Triazoles; Urinary Tract Infections | 1994 |
4 trial(s) available for triazoles and Acute Liver Injury, Drug-Induced
Article | Year |
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Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Amylose; Anaerobiosis; Animals; Anti-Bacterial Agents; Anura; Arginase; Arthritis, Rheumatoid; Asthma; Atmosphere; B-Lymphocytes; Basic Helix-Loop-Helix Transcription Factors; Bioelectric Energy Sources; Biofilms; Biofuels; Biomarkers; Biopolymers; Bioreactors; Brain; Brain Injuries, Traumatic; Breast Neoplasms; Calibration; Carbon Tetrachloride; Caspase 3; Catalysis; Catechin; Cations; Cattle; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Body; Cell Line, Tumor; Cell Plasticity; Chemical and Drug Induced Liver Injury; Chemistry Techniques, Synthetic; China; Chitosan; Chloride Channels; Chromatography, High Pressure Liquid; Chromosome Mapping; Cognition; Cognitive Dysfunction; Cohort Studies; Colitis, Ulcerative; Colloids; Coloring Agents; Congresses as Topic; Correlation of Data; Crystallization; Cyanoacrylates; Cyclohexane Monoterpenes; Cyprinidae; Cytochrome P-450 CYP1A1; Death, Sudden; Dent Disease; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Disease Progression; Disease Resistance; Disulfides; Drug Monitoring; Drug Stability; Ecotoxicology; Electricity; Electrodes; Endocytosis; Environmental Exposure; Environmental Monitoring; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal and Gastric Varices; Esters; Fagopyrum; Female; Ferrosoferric Oxide; Flame Retardants; Flavobacteriaceae; Flow Cytometry; Follow-Up Studies; Formoterol Fumarate; Fusarium; Garlic; Gastrointestinal Hemorrhage; Gene Expression; Genes, Plant; Genetic Markers; Glial Fibrillary Acidic Protein; Gliosis; Global Health; Glutathione Transferase; Glycine max; Gum Arabic; Hemostasis, Endoscopic; Hepatocytes; Hippocampus; Humans; Hydrogen-Ion Concentration; Illinois; Immunoglobulin G; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infant, Newborn; Infant, Small for Gestational Age; Injections, Intraperitoneal; Interleukin-4; Iowa; Iron; Ki-67 Antigen; Kidney; Kinetics; Kynurenine; Lakes; Levofloxacin; Lipid Peroxidation; Lipids; Liver; Liver Cirrhosis, Experimental; Magnetic Fields; Magnetic Iron Oxide Nanoparticles; Male; Manure; Maze Learning; Memory, Short-Term; Metal Nanoparticles; Metals, Heavy; Methane; Mice; Mice, Inbred C57BL; Mice, Knockout; Michigan; Microalgae; Microbial Consortia; Mitochondria; Models, Animal; Models, Chemical; Models, Neurological; Molecular Structure; Molecular Weight; Mutation; Myeloid-Derived Suppressor Cells; NADPH Oxidase 2; Neoplasm Recurrence, Local; Neurites; Neurons; Neuroprotective Agents; NF-kappa B; NIH 3T3 Cells; Nitric Oxide Synthase Type II; Nitrogen; Ohio; Ointments; Ontario; Organelle Biogenesis; Organophosphates; Organophosphorus Compounds; Oxidative Stress; Palladium; Particle Size; Pectins; Phenotype; Phytotherapy; Piperidines; Placenta; Plant Diseases; Plant Extracts; Polymers; Polymorphism, Genetic; Polyphenols; Powders; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Protein Kinase Inhibitors; Protein Structure, Secondary; Proteins; Pyridines; Pyrimidines; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; Recovery of Function; Recurrence; Reference Standards; Reference Values; Reproducibility of Results; Respiratory Function Tests; Retrospective Studies; Risk; Sensitivity and Specificity; Sewage; Signal Transduction; Sodium Glutamate; Soil; Solanum tuberosum; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spermatozoa; STAT3 Transcription Factor; Sulfamethoxazole; Tea; Temperature; Thermodynamics; Thrombin; Treatment Outcome; Triazoles; United States; Viscosity; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical; Water Purification; White Matter; Wisconsin; X-Ray Diffraction; Zea mays | 2013 |
Efficacy and safety of deferasirox compared with deferoxamine in sickle cell disease: two-year results including pharmacokinetics and concomitant hydroxyurea.
Topics: Acute Kidney Injury; Adolescent; Adult; Anemia, Sickle Cell; Benzoates; Cellulitis; Chelation Therapy; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Deferasirox; Deferoxamine; Drug Therapy, Combination; Female; Ferritins; Humans; Hydroxyurea; Iron Chelating Agents; Iron Overload; Male; Middle Aged; Prospective Studies; Transfusion Reaction; Triazoles; Young Adult | 2013 |
DRESS syndrome and reversible liver function abnormalities in patients with systemic lupus erythematosus treated with the highly selective JAK-1 inhibitor GSK2586184.
Topics: Adult; Azetidines; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity Syndrome; Female; Humans; Janus Kinase 1; Lupus Erythematosus, Systemic; Middle Aged; Protein Kinase Inhibitors; Randomized Controlled Trials as Topic; Triazoles | 2015 |
Voriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent fever.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Chemical and Drug Induced Liver Injury; Child; Chronic Disease; Female; Fever; Humans; Infusions, Intravenous; Male; Middle Aged; Mycoses; Neoplasms; Neutropenia; Prospective Studies; Pyrimidines; Triazoles; Voriconazole | 2002 |
98 other study(ies) available for triazoles and Acute Liver Injury, Drug-Induced
Article | Year |
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Permeabilized Cryopreserved Human Hepatocytes as an Exogenous Metabolic System in a Novel Metabolism-Dependent Cytotoxicity Assay for the Evaluation of Metabolic Activation and Detoxification of Drugs Associated with Drug-Induced Liver Injuries: Results w
Topics: Acetaminophen; Activation, Metabolic; Amiodarone; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Cytochrome P-450 Enzyme System; Glutathione; HEK293 Cells; Hepatocytes; Humans; Ketoconazole; Piperazines; Triazoles; Troglitazone | 2022 |
Toxicological effects of acute prothioconazole and prothioconazole-desthio administration on liver in male Chinese lizards (Eremias argus).
Topics: Animals; Chemical and Drug Induced Liver Injury; Liver; Lizards; Male; Oxidative Stress; Triazoles | 2022 |
Hepatic safety of the antifungal triazole agent posaconazole: characterization of adverse event reports in a manufacturer's safety database.
Topics: Antifungal Agents; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Humans; Invasive Fungal Infections; Triazoles | 2022 |
Comparison of Mold Active Triazoles as Primary Antifungal Prophylaxis in Patients With Newly Diagnosed Acute Myeloid Leukemia in the Era of Molecularly Targeted Therapies.
Topics: Adult; Antifungal Agents; Azoles; Chemical and Drug Induced Liver Injury; Echinocandins; Fungi; Humans; Invasive Fungal Infections; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Retrospective Studies; Triazoles; Voriconazole | 2022 |
Anastrozole and related glucuronic acid conjugate are electrophilic species.
Topics: Anastrozole; Animals; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Female; Glucuronic Acid; Humans; Nitriles; Rats; Triazoles | 2022 |
Exposure to high-performance benzotriazole ultraviolet stabilizers: Advance in toxicological effects, environmental behaviors and remediation mechanism using in-silica methods.
Topics: Chemical and Drug Induced Liver Injury; Humans; Risk Assessment; Triazoles; Ultraviolet Rays | 2023 |
Highlight report: hepatotoxicity of triazole fungicides.
Topics: Cell Line; Chemical and Drug Induced Liver Injury; Fungicides, Industrial; Humans; Pregnane X Receptor; Triazoles | 2019 |
Tebuconazole induced oxidative stress related hepatotoxicity in adult and larval zebrafish (Danio rerio).
Topics: Animals; Apoptosis; Catalase; Chemical and Drug Induced Liver Injury; Female; Fungicides, Industrial; Larva; Male; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Triazoles; Zebrafish | 2020 |
Combined toxicity of imidacloprid, acetochlor, and tebuconazole to zebrafish (Danio rerio): acute toxicity and hepatotoxicity assessment.
Topics: Animals; Catalase; Chemical and Drug Induced Liver Injury; Neonicotinoids; Nitro Compounds; Oxidative Stress; Superoxide Dismutase; Toluidines; Triazoles; Water Pollutants, Chemical; Zebrafish | 2020 |
Efficacy of Allium sativum oil to alleviate tebuconazol-induced oxidative stress in the liver of adult rats.
Topics: Animals; Antioxidants; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Flavonoids; Garlic; Glutathione; Glutathione Peroxidase; Liver; Male; Nitric Oxide; Oxidative Stress; Phenol; Plant Oils; Rats; Rats, Wistar; Superoxide Dismutase; Triazoles | 2019 |
Liver Enzyme Elevations in
Topics: Acrylamides; Adamantane; Adult; Alanine Transaminase; Aminopyridines; Aminoquinolines; Antimalarials; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Erythrocyte Transfusion; Erythrocytes; Female; Ferrous Compounds; Healthy Volunteers; Heterocyclic Compounds, 4 or More Rings; Humans; Indoles; Isoquinolines; Malaria, Falciparum; Male; Metallocenes; Parasitemia; Peroxides; Piperazines; Plasmodium falciparum; Primaquine; Pyrimidines; Quinolines; Spiro Compounds; Sulfones; Triazoles; Young Adult | 2020 |
Effects of difenoconazole on hepatotoxicity, lipid metabolism and gut microbiota in zebrafish (Danio rerio).
Topics: Animals; Chemical and Drug Induced Liver Injury; Dioxolanes; Gastrointestinal Microbiome; Larva; Lipid Metabolism; Triazoles; Water Pollutants, Chemical; Zebrafish | 2020 |
In vivo evaluation of combination therapy targeting the isoprenoid biosynthetic pathway.
Topics: Animals; Biosynthetic Pathways; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Diterpenes; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Therapy, Combination; Enzyme Inhibitors; Farnesyltranstransferase; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Mice, Inbred NOD; Mice, SCID; Pravastatin; Protein Prenylation; Terpenes; Triazoles; Xenograft Model Antitumor Assays | 2021 |
Fungicide bromuconazole has the potential to induce hepatotoxicity at the physiological, metabolomic and transcriptomic levels in rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Fungicides, Industrial; Furans; Liver; Male; Metabolomics; Rats; Transcriptome; Triazoles | 2021 |
Metabolic Activation of Cholestatic Drug-Induced Bile Acid-Dependent Toxicity in Human Sandwich-Cultured Hepatocytes.
Topics: Activation, Metabolic; Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Bile Acids and Salts; Biological Transport; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cholestasis; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Hepatocytes; Humans; Male; Rats; Rats, Sprague-Dawley; Tolvaptan; Toxicity Tests; Triazoles | 2017 |
Multicentre study of posaconazole delayed-release tablet serum level and association with hepatotoxicity and QTc prolongation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Delayed-Action Preparations; Electrocardiography; Female; Humans; Liver Function Tests; Male; Middle Aged; Retrospective Studies; Serum; Tablets; Triazoles; Young Adult | 2017 |
Bromuconazole-induced hepatotoxicity is accompanied by upregulation of PXR/CYP3A1 and downregulation of CAR/CYP2B1 gene expression.
Topics: Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Constitutive Androstane Receptor; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Fungicides, Industrial; Furans; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Kidney; Lethal Dose 50; Lipid Peroxidation; Male; No-Observed-Adverse-Effect Level; Oxidative Stress; Pregnane X Receptor; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Renal Insufficiency; Triazoles | 2017 |
Histopathological and proteomic responses in male Chinese rare minnow (Gobiocypris rarus) indicate hepatotoxicity following benzotriazole exposure.
Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Cyprinidae; Liver; Male; Proteome; Proteomics; Triazoles; Water Pollutants, Chemical | 2017 |
Modulatory effects of quercetin on liver histopathological, biochemical, hematological, oxidative stress and DNA alterations in rats exposed to graded doses of score 250.
Topics: Animals; Antioxidants; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Dioxolanes; DNA Damage; Dose-Response Relationship, Drug; Fungicides, Industrial; Lethal Dose 50; Liver; Male; Nucleic Acid Denaturation; Oxidative Stress; Quercetin; Rats, Wistar; Triazoles | 2018 |
Discovery of Potent and Selective Inhibitors of Cdc2-Like Kinase 1 (CLK1) as a New Class of Autophagy Inducers.
Topics: Acetaminophen; Animals; Autophagy; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Models, Molecular; Protective Agents; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Quinolines; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2017 |
Hepatotoxic combination effects of three azole fungicides in a broad dose range.
Topics: Animals; Azoles; Chemical and Drug Induced Liver Injury; Epoxy Compounds; Fungicides, Industrial; Imidazoles; Liver; Male; Organ Size; Rats; Rats, Wistar; Toxicity Tests, Subchronic; Triazoles | 2018 |
Bromodomain and Extraterminal (BET) Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Azepines; Cell Proliferation; Chemical and Drug Induced Liver Injury; Hep G2 Cells; Hepatectomy; Hepatocytes; Humans; Liver Regeneration; Male; Mice; Mice, Inbred C57BL; Proteins; Signal Transduction; Triazoles; Zebrafish | 2018 |
Tolerability of isavuconazole after posaconazole toxicity in leukaemia patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Leukemia; Liver Function Tests; Male; Middle Aged; Mycoses; Nitriles; Pyridines; Retrospective Studies; Triazoles; Young Adult | 2019 |
Isavuconazole: Case Report and Pharmacokinetic Considerations.
Topics: Administration, Oral; Antifungal Agents; Aspergillosis; Aspergillus flavus; Bronchoalveolar Lavage Fluid; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Drug Monitoring; Female; Half-Life; Humans; Immunocompromised Host; Nitriles; Pyridines; Tandem Mass Spectrometry; Triazoles; Voriconazole; Young Adult | 2018 |
Organic semiconducting nanoprobe with redox-activatable NIR-II fluorescence for in vivo real-time monitoring of drug toxicity.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Fluorescent Dyes; Hep G2 Cells; Humans; Maleates; Mice; Nanostructures; Nitric Oxide; Oxidation-Reduction; Polystyrenes; Semiconductors; Spectroscopy, Near-Infrared; Triazoles | 2018 |
Can Galactose Be Converted to Glucose in HepG2 Cells? Improving the
Topics: Amiodarone; Benzbromarone; Chemical and Drug Induced Liver Injury; Galactose; Glucose; Hep G2 Cells; Humans; Metabolomics; Mitochondria, Liver; Piperazines; Triazoles; Troglitazone; Tumor Cells, Cultured | 2019 |
A reduced grade of liver fibro-steatosis after raltegravir, maraviroc and fosamprenavir in an HIV/HCV co-infected patient with chronic hepatitis, cardiomyopathy, intolerance to nelfinavir and a marked increase of serum creatine phosphokinase levels probab
Topics: Adult; Carbamates; Cardiomyopathies; Chemical and Drug Induced Liver Injury; Creatine Kinase; Cyclohexanes; Drug Substitution; Drug Therapy, Combination; Fatty Liver; Furans; Hepatitis C, Chronic; HIV Fusion Inhibitors; HIV Infections; HIV Integrase Inhibitors; HIV Protease Inhibitors; Humans; Liver Cirrhosis; Male; Maraviroc; Organophosphates; Pyrrolidinones; Raltegravir Potassium; Sulfonamides; Triazoles | 2012 |
[Effectiveness of the correction of hepatotoxicity during combined chemoradiotherapy for cancer patients].
Topics: Adult; Aged; Brain Neoplasms; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Chemoradiotherapy; Drug Administration Schedule; Female; Glioma; Humans; Infusions, Intravenous; Liver; Male; Middle Aged; Neoplasms; Protective Agents; Severity of Illness Index; Treatment Outcome; Triazoles | 2013 |
Safety of deferasirox: a retrospective cohort study on the risks of gastrointestinal, liver and renal events.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Benzoates; Chemical and Drug Induced Liver Injury; Deferasirox; Female; Gastrointestinal Hemorrhage; Humans; Incidence; Iron Chelating Agents; Iron Overload; Male; Middle Aged; Necrosis; Proportional Hazards Models; Retrospective Studies; Taiwan; Triazoles | 2014 |
Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma.
Topics: Animals; Atropine; Captopril; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Flutamide; Lamivudine; Liver; Male; Mannitol; Metabolomics; Methotrexate; Neomycin; Oxidative Stress; Phenytoin; Piperazines; Propylthiouracil; Rats; Rats, Wistar; Streptomycin; Triazoles; Valproic Acid; Vancomycin; Zidovudine | 2014 |
Hepatotoxic effects of (tri)azole fungicides in a broad dose range.
Topics: Animals; Chemical and Drug Induced Liver Injury; Constitutive Androstane Receptor; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Epoxy Compounds; Fungicides, Industrial; Gene Expression Regulation; Hepatocytes; Imidazoles; Male; Phenobarbital; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Triazoles | 2015 |
An unusual cause of jaundice in a patient with breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Biopsy; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Fatty Liver; Female; Humans; Jaundice; Liver; Liver Function Tests; Middle Aged; Nitriles; Triazoles | 2014 |
Changes in Gut Microbiota May Be Early Signs of Liver Toxicity Induced by Epoxiconazole in Rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Epoxy Compounds; Female; Gastrointestinal Tract; Microbiota; Rats; Rats, Sprague-Dawley; Triazoles | 2014 |
The deferiprone and deferasirox combination is efficacious in iron overloaded patients with β-thalassemia major: A prospective, single center, open-label study.
Topics: Adolescent; Adult; Benzoates; beta-Thalassemia; Chelation Therapy; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Deferasirox; Deferiprone; Drug Eruptions; Drug Therapy, Combination; Female; Ferritins; Gastrointestinal Diseases; Humans; Iron; Iron Chelating Agents; Iron Overload; Joint Diseases; Male; Prospective Studies; Proteinuria; Pyridones; Transfusion Reaction; Treatment Outcome; Triazoles; Young Adult | 2015 |
Establishment of a mouse model for amiodarone-induced liver injury and analyses of its hepatotoxic mechanism.
Topics: Alanine Transaminase; Amiodarone; Animals; Chemical and Drug Induced Liver Injury; Dexamethasone; Gadolinium; Ketoconazole; Kupffer Cells; Male; Mice; Mice, Inbred BALB C; Models, Animal; Triazoles | 2016 |
A case of anastrazole-related drug-induced autoimmune hepatitis.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Chemical and Drug Induced Liver Injury; Female; Hepatitis, Autoimmune; Humans; Nitriles; Triazoles | 2014 |
Oral Azole Antifungal Medications and Risk of Acute Liver Injury, Overall and by Chronic Liver Disease Status.
Topics: Administration, Oral; Adult; Antifungal Agents; California; Chemical and Drug Induced Liver Injury; Chronic Disease; Cohort Studies; Female; Humans; Liver Diseases; Liver Failure, Acute; Male; Middle Aged; Retrospective Studies; Transaminases; Triazoles | 2016 |
Preliminary characterization of a murine model for 1-bromopropane neurotoxicity: Role of cytochrome P450.
Topics: Animals; Atmosphere Exposure Chambers; Cerebral Cortex; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disease Models, Animal; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Hydrocarbons, Brominated; Injections, Intraperitoneal; Injections, Subcutaneous; Liver; Male; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Neurotoxicity Syndromes; Organ Size; ran GTP-Binding Protein; Solvents; Triazoles | 2016 |
Transcriptome analyses demonstrate that Peroxisome Proliferator-Activated Receptor α (PPARα) activity of an ultraviolet absorber, 2-(2'-hydroxy-3',5'-di-tert-butylphenyl)benzotriazole, as possible mechanism of their toxicity and the gender differences.
Topics: Animals; Chemical and Drug Induced Liver Injury; Computational Biology; Databases, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Developmental; Liver; Male; Oligonucleotide Array Sequence Analysis; PPAR alpha; Rats, Sprague-Dawley; RNA, Messenger; Sex Factors; Time Factors; Triazoles | 2016 |
Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice.
Topics: Animals; Chemical and Drug Induced Liver Injury; Constitutive Androstane Receptor; Dose-Response Relationship, Drug; Fungicides, Industrial; Gene Expression Regulation; Hepatocytes; Humans; Imidazoles; Male; Mice; Mice, Inbred C57BL; Phenobarbital; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Triazoles; Up-Regulation | 2017 |
Solithromycin rejection chills antibiotic sector.
Topics: Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Humans; Macrolides; Triazoles; United States; United States Food and Drug Administration | 2017 |
Mode of action for reproductive and hepatic toxicity inferred from a genomic study of triazole antifungals.
Topics: Aging; Animals; Antifungal Agents; Chemical and Drug Induced Liver Injury; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Gestational Age; Infertility, Male; Liver; Liver Diseases; Male; Nitriles; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; Reproduction; Testis; Testosterone; Triazoles | 2009 |
Hepatic safety of voriconazole after allogeneic hematopoietic stem cell transplantation.
Topics: Adult; Antifungal Agents; Chemical and Drug Induced Liver Injury; Child; Cohort Studies; Drug Monitoring; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Liver; Liver Function Tests; Lymphocyte Depletion; Male; Opportunistic Infections; Pyrimidines; Retrospective Studies; Risk Factors; Statistics as Topic; T-Lymphocytes; Triazoles; Voriconazole | 2010 |
Posaconazole prophylaxis during induction therapy of patients with acute lymphoblastic leukaemia.
Topics: Adult; Alanine Transaminase; Antifungal Agents; Aspartate Aminotransferases; Aspergillus; Bilirubin; Candida; Chemical and Drug Induced Liver Injury; Chemoprevention; Female; Humans; Liver Function Tests; Male; Mycoses; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Triazoles; Young Adult | 2011 |
Letrozole induces hepatotoxicity without causing oxidative stress: the protective effect of melatonin.
Topics: Animals; Antioxidants; Aromatase Inhibitors; Chemical and Drug Induced Liver Injury; Female; Letrozole; Liver; Melatonin; Nitriles; Oxidative Stress; Rats; Rats, Sprague-Dawley; Triazoles | 2011 |
Voriconazole-associated salt-losing nephropathy.
Topics: Aged; Antifungal Agents; Biomarkers; Chemical and Drug Induced Liver Injury; Fluid Therapy; Humans; Hyponatremia; Kidney Diseases; Liver; Male; Neurophysins; Protein Precursors; Pyrimidines; Renin; Sodium; Sodium Chloride; Time Factors; Treatment Outcome; Triazoles; Vasopressins; Voriconazole; Water-Electrolyte Balance | 2010 |
Deferasirox induced liver injury in haemochromatosis.
Topics: Benzoates; Chemical and Drug Induced Liver Injury; Deferasirox; Female; Hemochromatosis; Humans; Iron Chelating Agents; Middle Aged; Triazoles | 2010 |
Ticlopidine-induced hepatotoxicity in a GSH-depleted rat model.
Topics: Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Glutathione; Platelet Aggregation Inhibitors; Protein Binding; Rats; Ticlopidine; Triazoles | 2011 |
Management of voriconazole hepatotoxicity in a lung transplant patient.
Topics: Alanine Transaminase; Antifungal Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Lung Transplantation; Middle Aged; Pulmonary Aspergillosis; Pyrimidines; Treatment Outcome; Triazoles; Voriconazole | 2011 |
Propiconazole induces alterations in the hepatic metabolome of mice: relevance to propiconazole-induced hepatocarcinogenesis.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Fungicides, Industrial; Liver; Male; Metabolome; Mice; Mice, Inbred Strains; Molecular Structure; Organ Size; Triazoles | 2011 |
A case of drug-induced hepatic injury associated with sitagliptin.
Topics: Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Humans; Hypoglycemic Agents; Jaundice; Liver; Male; Microscopy, Electron, Transmission; Middle Aged; Pyrazines; Sitagliptin Phosphate; Triazoles | 2011 |
Deferasirox protects against iron-induced hepatic injury in Mongolian gerbil.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Benzoates; Caspase 3; Chemical and Drug Induced Liver Injury; Deferasirox; Disease Models, Animal; DNA Fragmentation; Ferritins; Gerbillinae; Iron Chelating Agents; Iron Overload; Iron-Dextran Complex; Male; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Translational Research, Biomedical; Triazoles | 2011 |
Deferasirox induced liver injury in haemochromatosis.
Topics: Administration, Oral; Benzoates; Chemical and Drug Induced Liver Injury; Deferasirox; Diagnosis, Differential; Dose-Response Relationship, Drug; Female; Hemochromatosis; Humans; Iron Chelating Agents; Middle Aged; Triazoles | 2011 |
Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzoquinones; Blotting, Western; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Crystallography, X-Ray; Female; Heart; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; K562 Cells; Lactams, Macrocyclic; Male; Mice; Mice, Nude; Mice, SCID; Neoplasms; Rabbits; Rats; Rats, Sprague-Dawley; Triazoles; Xenograft Model Antitumor Assays | 2012 |
The hepatocarcinogenic conazoles: cyproconazole, epoxiconazole, and propiconazole induce a common set of toxicological and transcriptional responses.
Topics: Administration, Oral; Animals; Carcinogens; Cell Proliferation; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Epoxy Compounds; Fungicides, Industrial; Gene Expression Regulation, Neoplastic; Hepatocytes; Liver; Male; Mice; Mice, Inbred Strains; Oligonucleotide Array Sequence Analysis; Transforming Growth Factor alpha; Triazoles | 2012 |
Severe hepatotoxicity and acute renal failure caused by diniconazole.
Topics: Acute Kidney Injury; Chemical and Drug Induced Liver Injury; Humans; Male; Middle Aged; Severity of Illness Index; Triazoles | 2012 |
[Quantitative evaluation method of the informational value of initial symptoms based on Bayesian theory].
Topics: Antifungal Agents; Bayes Theorem; Chemical and Drug Induced Liver Injury; Drug Information Services; Drug-Related Side Effects and Adverse Reactions; Exanthema; Humans; Pharmacists; Probability; Pyrimidines; Symptom Assessment; Triazoles; Voriconazole | 2012 |
Mouse precision-cut liver slices as an ex vivo model to study idiosyncratic drug-induced liver injury.
Topics: Animals; Benzodiazepines; Biomarkers; Carbamazepine; Cell Survival; Chemical and Drug Induced Liver Injury; Chemokines; Chromans; Clozapine; Cytokines; Diclofenac; Drug Synergism; Female; Glutathione; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; In Vitro Techniques; Ketoconazole; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Nitrogen Oxides; Olanzapine; Pyrimidines; Thiazolidinediones; Triazoles; Troglitazone; Voriconazole | 2012 |
Real-time concurrent monitoring of apoptosis, cytosolic calcium, and mitochondria permeability transition for hypermulticolor high-content screening of drug-induced mitochondrial dysfunction-mediated hepatotoxicity.
Topics: Apoptosis; Benzophenones; Calcium; Caspase 3; Chemical and Drug Induced Liver Injury; Chromans; Hep G2 Cells; Humans; Image Processing, Computer-Assisted; Imidazoles; Liver; Microscopy, Fluorescence; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nitrophenols; Piperazines; Thiazolidinediones; Tolcapone; Triazoles; Troglitazone | 2012 |
Voriconazole hepatotoxicity in severe liver dysfunction.
Topics: Adult; Aged; Amphotericin B; Analysis of Variance; Antifungal Agents; Aspergillosis; Chemical and Drug Induced Liver Injury; Cohort Studies; Female; Humans; Liver; Liver Function Tests; Male; Middle Aged; Observation; Pyrimidines; Triazoles; Voriconazole | 2013 |
[Rizatriptan-induced liver toxicity. Report of a case].
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Female; Humans; Immune Complex Diseases; Jaundice, Obstructive; Migraine Disorders; Serotonin Receptor Agonists; Time Factors; Triazoles; Tryptamines | 2013 |
[Toxic hepatitis after intake of raspberries].
Topics: Chemical and Drug Induced Liver Injury; Food Contamination; Foodborne Diseases; Fruit; Fungicides, Industrial; Humans; Ivermectin; Male; Middle Aged; Pesticide Residues; Pyrethrins; Rosaceae; Triazoles | 2013 |
Implication of hepatic transporters (MDR1 and MRP2) in inflammation-associated idiosyncratic drug-induced hepatotoxicity investigated by microvolume cytometry.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; Biological Transport; Chemical and Drug Induced Liver Injury; Flow Cytometry; Fluoroquinolones; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Inflammation; Ketolides; Lipopolysaccharides; Liver; Naphthyridines; Piperazines; Sulfonamides; Triazoles; Tumor Necrosis Factor-alpha; Xenobiotics | 2013 |
[Acute liver failure in nefazodone therapy? A case report].
Topics: Antidepressive Agents; Chemical and Drug Induced Liver Injury; Depressive Disorder; Fatal Outcome; Humans; Liver Failure, Acute; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Piperazines; Recurrence; Triazoles | 2002 |
Withdrawing drugs: nefazodone, the start of the latest saga.
Topics: Antidepressive Agents, Second-Generation; Chemical and Drug Induced Liver Injury; Drug Approval; Drug Monitoring; Humans; Piperazines; Product Surveillance, Postmarketing; Triazoles | 2003 |
Hepatic injury and pancreatitis during treatment with serotonin reuptake inhibitors: data from the World Health Organization (WHO) database of adverse drug reactions.
Topics: Adverse Drug Reaction Reporting Systems; Bayes Theorem; Chemical and Drug Induced Liver Injury; Cyclohexanols; Databases, Factual; Humans; Neural Networks, Computer; Pancreatitis; Piperazines; Selective Serotonin Reuptake Inhibitors; Triazoles; Venlafaxine Hydrochloride; World Health Organization | 2003 |
Nefazodone (Serzone) withdrawn because of hepatotoxicity.
Topics: Antidepressive Agents, Second-Generation; Chemical and Drug Induced Liver Injury; Humans; Jaundice; Liver; Necrosis; Piperazines; Triazoles | 2003 |
The CYP inhibitor 1-aminobenzotriazole does not prevent oxidative stress associated with alcohol-induced liver injury in rats and mice.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Electron Spin Resonance Spectroscopy; Enzyme Induction; Enzyme Inhibitors; Ethanol; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Rats; Rats, Wistar; RNA, Messenger; Triazoles | 2003 |
[Withdrawal of a drug from the market for safety reasons: process and communication].
Topics: Adverse Drug Reaction Reporting Systems; Antidepressive Agents, Second-Generation; Attitude of Health Personnel; Chemical and Drug Induced Liver Injury; Communication; Drug Industry; Drug Information Services; Drug-Related Side Effects and Adverse Reactions; Humans; Interprofessional Relations; Piperazines; Switzerland; Triazoles | 2004 |
Iron chelation therapy.
Topics: Administration, Oral; Benzoates; beta-Thalassemia; Chelation Therapy; Chemical and Drug Induced Liver Injury; Deferasirox; Deferiprone; Deferoxamine; Drug Therapy, Combination; Humans; Infusions, Intravenous; Iron Chelating Agents; Iron Overload; Isoniazid; Pyridones; Pyridoxal; Survival; Triazoles | 2005 |
Investigation of the potential relationships between plasma voriconazole concentrations and visual adverse events or liver function test abnormalities.
Topics: Alanine Transaminase; Alkaline Phosphatase; Antifungal Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cohort Studies; Female; Humans; Liver Function Tests; Male; Pyrimidines; Regression Analysis; Retrospective Studies; Risk Assessment; ROC Curve; Triazoles; Vision Disorders; Voriconazole | 2006 |
Medical management of depression.
Topics: Chemical and Drug Induced Liver Injury; Depressive Disorder; Duloxetine Hydrochloride; Humans; Liver Function Tests; Piperazines; Selective Serotonin Reuptake Inhibitors; Thiophenes; Triazoles | 2006 |
Primary hepatic invasive aspergillosis with progression after rituximab therapy for a post transplantation lymphoproliferative disorder.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antifungal Agents; Antineoplastic Agents; Aspergillosis; Chemical and Drug Induced Liver Injury; Fatal Outcome; Female; Galactose; Graft vs Host Disease; Humans; Liver Diseases; Lymphoproliferative Disorders; Mannans; Middle Aged; Pyrimidines; Rituximab; Splenic Diseases; Stem Cell Transplantation; Transplantation, Homologous; Triazoles; Voriconazole | 2006 |
Anastrozole-induced hepatotoxicity.
Topics: Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Lobular; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Diseases; Liver Function Tests; Nausea; Nitriles; Triazoles | 2006 |
Liver toxicity after treatment with gefitinib and anastrozole: drug-drug interactions through cytochrome p450?
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Gefitinib; Humans; Isoenzymes; Lymphatic Metastasis; Middle Aged; Nitriles; Quinazolines; Triazoles | 2006 |
Severe acute hepatitis in a patient treated with anastrozole.
Topics: Anastrozole; Aromatase Inhibitors; Chemical and Drug Induced Liver Injury; Fatal Outcome; Female; Humans; Middle Aged; Nitriles; Triazoles | 2007 |
Voriconazole: serious adverse effects and interactions.
Topics: Adult; Antifungal Agents; Chemical and Drug Induced Liver Injury; Child; Drug Interactions; France; Heart Diseases; Humans; Mental Disorders; Pyrimidines; Skin Diseases; Triazoles; Vision Disorders | 2007 |
Toxicogenomic study of triazole fungicides and perfluoroalkyl acids in rat livers predicts toxicity and categorizes chemicals based on mechanisms of toxicity.
Topics: Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Fluorocarbons; Fungicides, Industrial; Hormones; Liver; Male; Oligonucleotide Array Sequence Analysis; Organ Size; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Testosterone; Thyroid Hormones; Triazoles; Weight Gain | 2007 |
Posaconazole prophylaxis in hematologic cancer.
Topics: Antifungal Agents; Bilirubin; Chemical and Drug Induced Liver Injury; Fluconazole; Graft vs Host Disease; Humans; Liver Diseases; Mycoses; Transaminases; Triazoles | 2007 |
Lack of cross-hepatotoxicity between voriconazole and posaconazole.
Topics: Aged; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Chemical and Drug Induced Liver Injury; Humans; Pyrimidines; Triazoles; Voriconazole | 2007 |
Hepatotoxicity of oral and intravenous voriconazole in relation to cytochrome P450 polymorphisms.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Female; Genetic Predisposition to Disease; Humans; Injections, Intravenous; Liver; Male; Middle Aged; Polymorphism, Genetic; Pyrimidines; Retrospective Studies; Triazoles; Voriconazole | 2007 |
Non-carboxylic analogues of naproxen: design, synthesis, and pharmacological evaluation of some 1,3,4-oxadiazole/thiadiazole and 1,2,4-triazole derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Drug Design; Edema; Liver; Liver Function Tests; Male; Mice; Molecular Structure; Naproxen; Oxadiazoles; Pain; Rats; Stomach Ulcer; Thiadiazoles; Triazoles | 2007 |
(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(1-methyl-1h-1,2,4-triazol-5-yl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid (BMS-644950): a rationally designed orally efficacious 3-hydroxy-3-methylglutaryl coenzyme-a reductase inhibitor with
Topics: Administration, Oral; Animals; Biological Availability; Chemical and Drug Induced Liver Injury; Cholesterol; Crystallography, X-Ray; Dogs; Female; Guinea Pigs; Haplorhini; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Liver; Models, Molecular; Muscle Cells; Pyrimidines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2008 |
Role of platelet-activating factor in pathogenesis of galactosamine-lipopolysaccharide-induced liver injury.
Topics: Animals; Azepines; Cell Adhesion; Cells, Cultured; Chemical and Drug Induced Liver Injury; Endothelium; Escherichia coli; Galactosamine; Lipopolysaccharides; Liver; Male; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Triazoles; Tumor Necrosis Factor-alpha | 1996 |
Neither platelet activating factor nor leukotrienes are critical mediators of liver injury after lipopolysaccharide administration.
Topics: Administration, Oral; Alanine Transaminase; Animals; Azepines; Blood Platelets; Chemical and Drug Induced Liver Injury; Female; Fibrinogen; Hydroxyurea; Injections, Intraperitoneal; Injections, Intravenous; Leukotrienes; Lipopolysaccharides; Lipoxygenase Inhibitors; Liver; Liver Diseases; Necrosis; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thrombocytopenia; Triazoles | 1997 |
Adverse effect of nefazodone: hepatitis.
Topics: Adult; Antidepressive Agents, Second-Generation; Chemical and Drug Induced Liver Injury; Depression; Humans; Male; Phobic Disorders; Piperazines; Triazoles | 1999 |
Reversible nefazodone-induced liver failure.
Topics: Antidepressive Agents, Second-Generation; Biopsy; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Female; Humans; Liver; Liver Cirrhosis, Alcoholic; Liver Failure; Middle Aged; Piperazines; Triazoles | 2000 |
Hepatoprotection by dimethyl sulfoxide. III. Role of inhibition of the bioactivation and covalent bonding of chloroform.
Topics: Alanine Transaminase; Allyl Compounds; Animals; Binding Sites; Chemical and Drug Induced Liver Injury; Chloroform; Cytochrome P-450 CYP2E1 Inhibitors; Dimethyl Sulfoxide; Enzyme Inhibitors; Free Radical Scavengers; Liver; Male; Rats; Rats, Sprague-Dawley; Sulfides; Time Factors; Triazoles | 2000 |
Hepatotoxicity associated with the new antidepressants.
Topics: Adult; Aged; Antidepressive Agents; Chemical and Drug Induced Liver Injury; Depressive Disorder; Drug Monitoring; Female; Humans; Incidence; Liver Diseases; Piperazines; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Triazoles | 2002 |
From the Food and Drug Administration.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Second-Generation; Antineoplastic Agents; Arthritis, Psoriatic; Benzamides; Chemical and Drug Induced Liver Injury; Cyclohexanones; Enzyme Inhibitors; Etanercept; Gastrointestinal Neoplasms; Humans; Imatinib Mesylate; Immunoglobulin G; Infant; Liver Failure; Nitrobenzoates; Orphan Drug Production; Piperazines; Pyrimidines; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Triazoles; Tyrosinemias; United States; United States Food and Drug Administration | 2002 |
Hepatic adverse reactions associated with nefazodone.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Antidepressive Agents, Second-Generation; Canada; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Liver Function Tests; Male; Middle Aged; Piperazines; Triazoles | 2002 |
Effects of inflammation on peroxisomal enzyme activities, catalase synthesis, and lipid metabolism.
Topics: Alcohol Oxidoreductases; Allylisopropylacetamide; Animals; Catalase; Chemical and Drug Induced Liver Injury; D-Amino-Acid Oxidase; Fatty Acids; Inflammation; Liver; Male; Microbodies; Nafenopin; Organoids; Oxidoreductases; Rats; Triazoles; Turpentine; Urate Oxidase | 1977 |
The hepatotoxicity of 3-amino-1,2,4-triazole and carbon disulphide in phenobarbitone-treated starved rats.
Topics: Alanine Transaminase; Amitrole; Animals; Carbon Disulfide; Chemical and Drug Induced Liver Injury; Liver; Male; Phenobarbital; Rats; Starvation; Time Factors; Triazoles | 1978 |
Effect of 3-amino-1,2,4-triazole on carbon tetrachloride-induced necrosis.
Topics: Alanine Transaminase; Amitrole; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Depression, Chemical; Liver Diseases; Male; Necrosis; Rats; Triazoles | 1977 |
[Protective effect of a platelet activating factor antagonist in experimental liver injury].
Topics: Animals; Azepines; Chemical and Drug Induced Liver Injury; Endotoxins; Galactosamine; Liver; Malondialdehyde; Peroxidase; Platelet Activating Factor; Rats; Rats, Inbred Strains; Superoxide Dismutase; Triazoles | 1990 |
Modifying effect of 3-amino-1,2,4-triazole on phenobarbital-induced changes in rat liver.
Topics: Amitrole; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochromes; Drug Antagonism; Endoplasmic Reticulum; Enzyme Induction; Herbicides; Liver; Liver Diseases; Male; Microscopy, Electron; Microsomes, Liver; Necrosis; Paralysis; Phenobarbital; Rats; Triazoles; Zoxazolamine | 1972 |
[Toxicology of chemical sweetening agents].
Topics: Abnormalities, Drug-Induced; Animals; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Chromosome Aberrations; Chromosome Disorders; Cyclamates; Cyclohexylamines; Depression, Chemical; Esters; Guinea Pigs; Humans; Kidney Diseases; Mice; Pancreatic Diseases; Peptides; Phenylalanine; Photosensitivity Disorders; Rats; Saccharin; Sweetening Agents; Tolbutamide; Triazoles; Urinary Bladder Neoplasms | 1971 |
[A comparative evaluation of the toxic and possible carcinogenic effect of benzotriazol and phenidon].
Topics: Animals; Carcinogens; Chemical and Drug Induced Liver Injury; Female; Fibroma; Leukemia, Experimental; Lung Diseases; Lung Neoplasms; Male; Mesentery; Mice; Neoplasms, Experimental; Rats; Sarcoma, Experimental; Splenic Diseases; Triazoles | 1970 |