triazolam and Sleep Initiation and Maintenance Disorders
triazolam has been researched along with Sleep Initiation and Maintenance Disorders in 170 studies
Triazolam: A short-acting benzodiazepine used in the treatment of insomnia. Some countries temporarily withdrew triazolam from the market because of concerns about adverse reactions, mostly psychological, associated with higher dose ranges. Its use at lower doses with appropriate care and labeling has been reaffirmed by the FDA and most other countries.
Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.
Research Excerpts
Excerpt | Relevance | Reference |
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"In a parallel-group, placebo-controlled, polysomnographic study with randomization, the possible occurrence of rebound insomnia was evaluated in 24 patients suffering from moderate to severe chronic insomnia and receiving either triazolam 0." | 9.07 | Zolpidem and rebound insomnia--a double-blind, controlled polysomnographic study in chronic insomniac patients. ( Attali, P; de la Giclais, B; Monti, D; Monti, JM; Morselli, PL; Zipfel, A, 1994) |
"Within a double-blind, comparative study on the effects of the long-half-life benzodiazepine (BDZ), quazepam, and the short-half-life BDZ, triazolam, on clinical symptomatology, sleep and anxiety of 45 patients with insomnia based on a mild to moderate generalized anxiety disorder (GAD) (ICD-9 code: 307." | 9.07 | Insomnia in generalized anxiety disorder: polysomnographic, psychometric and clinical investigations before, during and after therapy with a long- versus a short-half-life benzodiazepine (quazepam versus triazolam). ( Anderer, P; Brandstätter, N; Frey, R; Grünberger, J; Klösch, G; Mandl, M; Saletu, B; Wetter, T; Zeitlhofer, J, 1994) |
"A case of repetitive hallucinations during treatment with a therapeutic dosage of triazolam (0." | 7.69 | Hallucinations after a therapeutic dose of benzodiazepine hypnotics with co-administration of erythromycin. ( Kaneko, S; Kondo, T; Mihara, K; Morita, S; Otani, K; Tokinaga, N, 1996) |
" The dosage was doubled after nights 2 and 9 if good sleep was not produced." | 6.64 | Multi-clinic cross-over comparison of triazolam (Halcion) and placebo in the treatment of co-existing insomnia and anxiety in anxious out-patients. ( Fabre, LF; Smith, WT, 1977) |
"Triazolam is a triazolobenzodiazepine with hypnotic properties, advocated for use in acute or chronic insomnia, situational insomnia in hospitalised patients, and insomnia associated with other disease states." | 6.15 | Triazolam: a review of its pharmacological properties and therapeutic efficacy in patients with insomnia. ( Avery, GS; Brogden, RN; Heel, RC; Pakes, GE; Speight, TM, 1981) |
"In a parallel-group, placebo-controlled, polysomnographic study with randomization, the possible occurrence of rebound insomnia was evaluated in 24 patients suffering from moderate to severe chronic insomnia and receiving either triazolam 0." | 5.07 | Zolpidem and rebound insomnia--a double-blind, controlled polysomnographic study in chronic insomniac patients. ( Attali, P; de la Giclais, B; Monti, D; Monti, JM; Morselli, PL; Zipfel, A, 1994) |
"Within a double-blind, comparative study on the effects of the long-half-life benzodiazepine (BDZ), quazepam, and the short-half-life BDZ, triazolam, on clinical symptomatology, sleep and anxiety of 45 patients with insomnia based on a mild to moderate generalized anxiety disorder (GAD) (ICD-9 code: 307." | 5.07 | Insomnia in generalized anxiety disorder: polysomnographic, psychometric and clinical investigations before, during and after therapy with a long- versus a short-half-life benzodiazepine (quazepam versus triazolam). ( Anderer, P; Brandstätter, N; Frey, R; Grünberger, J; Klösch, G; Mandl, M; Saletu, B; Wetter, T; Zeitlhofer, J, 1994) |
"A double-blind study comparing zopiclone and triazolam, in 48 healthy, chronic insomniacs, was undertaken in two centers to compare the hypnotic and withdrawal effects of both compounds." | 5.06 | A comparison of the efficacy, safety and withdrawal effects of zopiclone and triazolam in the treatment of insomnia. ( Bourgouin, J; Fleming, JA; Mayes, C; McClure, DJ; Phillips, R, 1990) |
"Twelve volunteers with a complaint of chronic insomnia participated in a placebo-controlled, double-blind, crossover study of the effects of buspirone t." | 5.05 | Buspirone: an anxiolytic without sedative effect. ( Bliwise, NG; Cohen, SA; Dement, WC; Seidel, WF, 1985) |
"6 mg) or flurazepam (30 mg) was given to chronic insomniac patients for 7 consecutive nights in parallel, double-blind design." | 5.04 | Methodology for demonstrating sustained efficacy of hypnotics: a comparative study of triazolam and flurazepam. ( Lasagna, L; Sundaresan, PR; Wardell, WM; Weintraub, M, 1979) |
"A case of repetitive hallucinations during treatment with a therapeutic dosage of triazolam (0." | 3.69 | Hallucinations after a therapeutic dose of benzodiazepine hypnotics with co-administration of erythromycin. ( Kaneko, S; Kondo, T; Mihara, K; Morita, S; Otani, K; Tokinaga, N, 1996) |
"Insomnia and anxiety decreased in 12 outpatients taking triazolam following alcohol withdrawal." | 3.65 | Pilot open-label study of triazolam in the treatment of insomnia following alcohol withdrawal. ( Fabre, LF; Gainey, A; Kemple, S; McLendon, DM; Metzler, CM, 1977) |
"It has been reported that insomnia characterized by difficulty returning to sleep following a nocturnal awakening, otherwise defined as the middle-of-the-night (MOTN) insomnia, is a common form of insomnia in adults with growing prevalence by increasing age." | 2.84 | Effects of different doses of triazolam in the middle-of-the-night insomnia: a double-blind, randomized, parallel group study. ( Biggio, G; Ferini Strambi, L; Galbiati, A; Marelli, S; Zucconi, M, 2017) |
"Previous studies have shown that insomniacs self-administer hypnotics at high nightly rates." | 2.70 | Treatment regimen and hypnotic self-administration. ( Bonahoom, A; Pedrosi, B; Roehrs, T; Rosenthal, L; Roth, T, 2001) |
"Rebound effects after withdrawal from hypnotics are believed to trigger their chronic use and to enhance the risk of tolerance and dependence." | 2.70 | A double-blind, randomized and placebo-controlled study on the polysomnographic withdrawal effects of zopiclone, zolpidem and triazolam in healthy subjects. ( Backhaus, J; Berger, M; Feige, B; Hohagen, F; Hornyak, M; Riemann, D; Voderholzer, U, 2001) |
"More triazolam was chosen at night than during the day." | 2.70 | Nighttime versus daytime hypnotic self-administration. ( Bonahoom, A; Pedrosi, B; Roehrs, T; Roth, T; Zorick, F, 2002) |
"However, on the fourth day night-time insomnia induced by BL had recovered, and naps were shorter than the baseline." | 2.69 | Bright light treatment for night-time insomnia and daytime sleepiness in elderly people: comparison with a short-acting hypnotic. ( Fukuzawa, H; Ishizuka, Y; Kanba, S; Matsushita, Y; Usui, A, 2000) |
"Triazolam was self administered as many nights as placebo, but the number of placebo capsules self administered was twice that of triazolam capsules." | 2.68 | Hypnotic self administration and dose escalation. ( Pedrosi, B; Roehrs, T; Rosenthal, L; Roth, T, 1996) |
"Since homogeneous samples of insomniacs are difficult to recruit for pharmacotherapy studies, normal sleepers can be used to assess the protective effect of hypnotic drugs, under standardized nonconducive conditions." | 2.68 | Multidrug comparison (lorazepam, triazolam, zolpidem, and zopiclone) in situational insomnia: polysomnographic analysis by means of the cyclic alternating pattern. ( Boselli, M; Parrino, L; Smerieri, A; Spaggiari, MC; Terzano, MG, 1997) |
"The zolpidem group was bracketed by a placebo group and a positive control group taking 0." | 2.68 | Minimal rebound insomnia after treatment with 10-mg zolpidem. ( Roehrs, T; Roth, T; Scharf, MB; Vogel, GW; Walsh, JK; Ware, JC, 1997) |
"Twenty-four men and women with insomnia, age 21-50 years, self administered hypnotics under a single-choice with placebo, single-choice with triazolam (0." | 2.68 | Hypnotic self administration: forced-choice versus single-choice. ( Pedrosi, B; Roehrs, T; Rosenthal, L; Roth, T; Zorick, F, 1997) |
"This study asks whether insomniacs undergoing behavioral training need to do so while totally free of hypnotics." | 2.68 | Can we mix behavioral therapy with hypnotics when treating insomniacs? ( Hauri, PJ, 1997) |
"With temazepam this effect was more variable, with total wake time increased only with the second withdrawal period (39%)." | 2.67 | Rebound insomnia after only brief and intermittent use of rapidly eliminated benzodiazepines. ( Bixler, EO; Fee, EC; Kales, A; Manfredi, RL; Vela-Bueno, A; Vgontzas, AN, 1991) |
" In this double-blind study in geriatric patients, drugs were administered during 3 weeks and the therapeutic effects of zopiclone at optimal dosage (5 or 7." | 2.67 | Efficacy and safety of zopiclone and triazolam in the treatment of geriatric insomniacs. ( Bourgouin, J; Elie, R; Frenay, M; Le Morvan, P, 1990) |
"Triazolam-treated patients presented significantly more day-time-interdose anxiety than zopiclone as assessed by the weekly HARS and Clinical Global Assessment of Anxiety." | 2.67 | Zopiclone and triazolam in insomnia associated with generalized anxiety disorder: a placebo-controlled evaluation of efficacy and daytime anxiety. ( Beauclair, L; Beaudry, P; Chouinard, G; Fontaine, R; Le Morvan, P, 1990) |
"Triazolam treatment showed superior immediate treatment effects, while behavioral treatment showed superior treatment effects at follow-up, effects that accrued during the training period and differentially persisted at follow-up." | 2.67 | Efficacy of behavioral versus triazolam treatment in persistent sleep-onset insomnia. ( McClusky, HY; Milby, JB; Switzer, PK; Williams, V; Wooten, V, 1991) |
"Rebound insomnia, a worsening of sleep difficulty beyond baseline levels, can complicate the physician's attempt to use regularly scheduled drug holidays in the management of insomniac patients." | 2.67 | Feasibility of an every-other-night regimen in insomniac patients: subjective hypnotic effectiveness of quazepam, triazolam, and placebo. ( Scharf, MB, 1993) |
"178 patients suffering from insomnia were included in the study, data from 139 patients were used in the analyses." | 2.67 | Randomized, double blind trial of zolpidem 10 mg versus triazolam 0.25 mg for treatment of insomnia in general practice. ( Ahlstrøm, F; Rosenberg, J, 1994) |
"Rebound insomnia was studied in subjects, aged 25-50 years, with insomnia complaints and normal sleep, insomnia complaints and disturbed sleep, and normal sleep with no complaints (N = 21, n = 7 per group)." | 2.67 | Rebound insomnia in normals and patients with insomnia after abrupt and tapered discontinuation. ( Merlotti, L; Roehrs, T; Roth, T; Zorick, F, 1992) |
"The groups compared were patients with insomnia and disturbed sleep, insomnia and normal sleep, and healthy normals." | 2.67 | Rebound insomnia and hypnotic self administration. ( Merlotti, L; Roehrs, T; Roth, T; Zorick, F, 1992) |
"Subjects with rebound insomnia had poorer baseline sleep and a greater drug effect than did subjects without." | 2.67 | Rebound insomnia: duration of use and individual differences. ( Merlotti, L; Roehrs, T; Roth, T; Zorick, F, 1991) |
"The study subjects were chronic insomniacs with moderate levels of psychopathology and prior use of hypnotics." | 2.66 | Profile of mood states changes during and after 5 weeks of nightly triazolam administration. ( Bliwise, DL; Bliwise, NG; Cohen, SA; Dement, WC; Seidel, WF, 1988) |
"In patients without severe waking hypoxemia and without carbon dioxide retention, triazolam did not increase either nocturnal hypoxemia or respiratory events during sleep." | 2.66 | Effect of triazolam on sleep and arterial oxygen saturation in patients with chronic obstructive pulmonary disease. ( Dawson, A; Hajdukovic, RM; Mitler, MM; Timms, RM, 1988) |
"Sixty volunteers with insomnia participated in a randomized, double-blind, controlled clinical trial." | 2.66 | Effect of gradual withdrawal on the rebound sleep disorder after discontinuation of triazolam. ( Greenblatt, DJ; Harmatz, JS; Shader, RI; Zinny, MA, 1987) |
"Triazolam was administered to five psychiatric inpatients for a two-week period." | 2.66 | Behavioral side effects of triazolam in psychiatric inpatients: report of five cases. ( Bergiannaki, JD; Sakkas, PN; Soldatos, CR; Stefanis, CN, 1986) |
"Chlormethiazole and triazolam were found to be similarly effective in short-term use." | 2.66 | A double-blind controlled study of chlormethiazole and triazolam as hypnotics in the elderly. ( Bayer, AJ; Bayer, EM; Pathy, MS; Stoker, MJ, 1986) |
" In contrast, triazolam dosing did not significantly improve any of the major sleep efficiency parameters, and there was a rapid development of tolerance for the drug's slight initial effectiveness." | 2.66 | Comparison of short and long half-life benzodiazepine hypnotics: triazolam and quazepam. ( Bixler, EO; Kales, A; Manfredi, RL; Niklaus, DE; Soldatos, CR; Vela-Bueno, A, 1986) |
"Triazolam, 0." | 2.66 | Dose-related effects of triazolam and flurazepam on a circadian rhythm insomnia. ( Bliwise, NG; Cohen, SA; Dement, WC; Roth, T; Seidel, WF, 1986) |
" The recovery data compared favourably with those improvements noted during chronic administration of triazolam." | 2.65 | Chronic use of triazolam: the effects on the sleep patterns of insomniacs. ( Hyde, P; Linton, P; Pegram, V, 1980) |
"Triazolam 0." | 2.65 | The efficacy of triazolam and chloral hydrate in geriatric insomniacs. ( Grissom, T; Kramer, M; Lutz, T; Piccione, P; Roth, T; Zorick, F, 1980) |
"Sixty young male patients with insomniac disorders were treated with nitrazepam 5 mg or triazolam 0." | 2.65 | Comparison of nitrazepam 5 mg with triazolam 0.5 mg in young psychiatric insomniac inpatients. Double-blind single night cross-over study. ( Blumenthal, M; Byring, R; Koivula, K, 1980) |
" It is concluded that both active drugs were highly effective, with a minimum of side effects, in this type of insomnia and with the relatively low dosage used." | 2.65 | Triazolam (Halcion) versus flunitrazepam (Rohypnol) against midwinter insomnia in Northern Norway. ( Bratlid, T; Lingjaerde, O, 1981) |
"Triazolam (0." | 2.64 | Comparative efficacy of triazolam, flurazepam and placebo in out-patients insomniacs. ( Bowen, AJ, 1978) |
"Triazolam 0." | 2.64 | A clinical comparison of triazolam with placebo and with secobarbital in insomniac patients. ( Allens, GS; Okawa, KK, 1978) |
"Triazolam did not produce evidence of tolerance development after 2 weeks of treatment." | 2.64 | Multi-clinic double-blind comparison of triazolam (Halcion) and placebo administered for 14 consecutive nights in outpatients with insomnia. ( Brachfeld, J; Calvo, R; Fabre, LF; Metzler, C; Meyer, LR; Slowe, IA, 1978) |
"Experimental sleep disturbance (model insomnia) was produced by intermittent white noise and the administration of 10 mg of methylphenidate (MPD)." | 2.64 | Model insomnia, noise, and methylphenidate, used for the evaluation of hypnotic drugs. ( Honda, H; Okuma, T, 1978) |
" The dosage was doubled after nights 2 and 9 if good sleep was not produced." | 2.64 | Multi-clinic cross-over comparison of triazolam (Halcion) and placebo in the treatment of co-existing insomnia and anxiety in anxious out-patients. ( Fabre, LF; Smith, WT, 1977) |
"Triazolam was more successful than methyprylon in this respect (p=0-012)." | 2.64 | Hypnotic efficacy of triazolam and methyprylon ininsomniac in-patients. ( Linet, OI; Lomen, P, 1976) |
"Triazolam 0-5 mg was found to be preferred and to be superior to placebo, flurazepam and chloral hydrate in the treatment of insomnia." | 2.64 | Preference studies of triazolam with standard hypnotics in out-patients with insomnia. ( Fabre, LF; Harris, RT; McLendon, DM, 1976) |
"Rebound insomnia, reported intermittently with most of these agents, was short-lived and not clinically significant." | 2.38 | Comparative clinical profiles of triazolam versus other shorter-acting hypnotics. ( Coleman, BS; Jonas, JM; Kalinske, RW; Sheridan, AQ, 1992) |
"Rebound insomnia, a worsening of sleep compared with pretreatment levels, has been reported upon discontinuation of short half-life benzodiazepine hypnotics." | 2.38 | Rebound insomnia: a critical review. ( Gillin, JC; Johnson, LC; Spinweber, CL, 1989) |
"In general, chronic insomniacs showed all degrees of daytime alertness regardless of nocturnal sleep parameters." | 2.37 | Issues in the diagnosis and treatment of insomnia. ( Carskadon, M; Dement, W; Seidel, W, 1984) |
"In the small number of patients with chronic insomnia who have received extended treatment with loprazolam, no evidence of tolerance has occurred, although rebound insomnia was evident 3 days after drug withdrawal in several studies." | 2.37 | Loprazolam. A preliminary review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in insomnia. ( Clark, BG; Dawson, GW; Jue, SG; Ward, A, 1986) |
"Flurazepam is a long elimination half-life drug, and there is significant daytime sedation during short term use; with continued use this effect diminishes." | 2.36 | Sleep laboratory studies of hypnotic drugs: efficacy and withdrawal effects. ( Kales, A; Kales, JD, 1983) |
"The diagnosis and treatment of insomnia is a major clinical issue." | 2.36 | Rational basis for the use of sleeping pills. ( Dement, WC, 1983) |
" Although some studies showed the possibility of adverse effects of triazolam in older people, there have been few studies investigating these effects in a clinical setting." | 1.43 | Quantification of adverse effects of regular use of triazolam on clinical outcomes for older people with insomnia: a retrospective cohort study. ( Babazono, A; Maeda, T; Nishi, T; Yasui, M, 2016) |
"This paper addresses the pharmacokinetic properties of eszopiclone and the extent to which the longer half-life of eszopiclone compared to other commonly used hypnotics (immediate-release zolpidem, modified-release zolpidem, triazolam, zaleplon) may translate into either improved efficacy in enhancing sleep maintenance, or increased probability of residual sedative or performance-impairing effects." | 1.38 | Pharmacokinetic evaluation of eszopiclone: clinical and therapeutic implications. ( Greenblatt, DJ; Zammit, GK, 2012) |
"Triazolam was associated with longer total sleep time and increased Stage 2 sleep." | 1.36 | Retrograde effects of triazolam and zolpidem on sleep-dependent motor learning in humans. ( Kehne, JH; Malison, RT; Morgan, PT; Sprenger, KJ, 2010) |
"Rates of insomnia visits are somewhat higher for middle-aged (45 to 64 years of age) women, and data for female insomniacs suggest a trend toward diagnoses of depression compared with other (somatic) diagnoses for men." | 1.29 | Management of insomnia in office-based practice. National prevalence and therapeutic patterns. ( Brunton, SA; Radecki, SE, 1993) |
", type of insomnia, type of physician who prescribed the drug) variables; (2) to estimate the proportion of long-term users (> 3 mo); (3) to determine the frequency of different administration schedules; (4) to determine whether the kind of hypnotic drug prescribed according to the duration of its effect correlates with the type of sleep disorder or patient age; and (5) to compare the dosage used by the elderly with that used by adults." | 1.29 | Hypnotic drug use in Spain: a cross-sectional study based on a network of community pharmacies. Spanish Group for the Study of Hypnotic Drug Utilization. ( Alvarez, C; DeAbajo, FJ; del Barrio, H; Madurga, M; Montero, D; Palop, R; Rayón, P; Serrano-Castro, M, 1996) |
"Findings from a four-city study of the beneficial and adverse effects of hypnotics are reported." | 1.28 | The beneficial and adverse effects of hypnotics. ( Balter, MB; Uhlenhuth, EH, 1991) |
"Two noncontinuous sleep disturbances, insomnia in the elderly and transient insomnia in young and middle-aged adults, are probably the most acceptable indications for the use of benzodiazepines." | 1.28 | Clinical uses and advantages of low doses of benzodiazepine hypnotics. ( Vogel, G, 1992) |
"We conclude that the evaluation of insomnia by nonpsychiatrists is often incomplete and that hypnotic drugs may be inappropriately prescribed by these physicians." | 1.28 | Diagnosis and treatment of outpatient insomnia by psychiatric and nonpsychiatric physicians. ( Bauwens, SF; Shorr, RI, 1992) |
"Triazolam 0." | 1.27 | Triazolam as a hypnotic for geriatric patients. A double-blind cross-over comparison of nitrazepam and triazolam regarding effects on sleep and psychomotor performance. ( Björnson, G; Dehlin, O, 1983) |
"Early morning insomnia, a significant increase in wakefulness during the final hours of drug nights, occurred after 1 or 2 weeks of nightly administration of benzodiazepine hypnotics with short elimination half-lives, when tolerance had begun to develop." | 1.27 | Early morning insomnia with rapidly eliminated benzodiazepines. ( Bixler, EO; Kales, A; Kales, JD; Soldatos, CR, 1983) |
"Side effects involving agitation, e." | 1.27 | Agitation observed during treatment with newer hypnotic drugs. ( Regestein, QR; Reich, P, 1985) |
" This study used nocturnal polysomnography and daytime sleep/wake tendency measures (Multiple Sleep Latency Test, MSLT) to assess the efficacy and safety of a reduced triazolam dosage (0." | 1.27 | Efficacy of a reduced triazolam dose in elderly insomniacs. ( Roehrs, T; Roth, T; Wittig, R; Zorick, F, 1985) |
"Rebound insomnia, a worsening of sleep compared with baseline, occurred following withdrawal of triazolam, nitrazepam, and flunitrazepam after they had been given in only single, nightly doses for short periods." | 1.26 | Rebound insomnia. A potential hazard following withdrawal of certain benzodiazepines. ( Kales, A; Kales, JD; Scharf, MB; Soldatos, CR, 1979) |
"Rebound insomnia followed the withdrawal of three benzodiazepine hypnotic drugs, each of which had been administered in a single nightly dose for only short-term periods." | 1.26 | Rebound insomnia: a new clinical syndrome. ( Kales, A; Kales, JD; Scharf, MB, 1978) |
"Triazolam proved to be an effective hypnotic during the six weeks of treatment, with no withdrawal effects upon discontinuation." | 1.26 | [Effects of the chronic administration of triazolam 0.50 mg on the sleep of insomniacs]. ( Kaffeman, M; Roth, T; Sicklesteel, J; Stepanski, E; Zorick, F, 1982) |
Research
Studies (170)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 94 (55.29) | 18.7374 |
1990's | 61 (35.88) | 18.2507 |
2000's | 10 (5.88) | 29.6817 |
2010's | 5 (2.94) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
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Ferini Strambi, L | 1 |
Marelli, S | 1 |
Zucconi, M | 2 |
Galbiati, A | 1 |
Biggio, G | 1 |
Min, JY | 1 |
Min, KB | 1 |
Maeda, T | 1 |
Babazono, A | 1 |
Nishi, T | 1 |
Yasui, M | 1 |
Hirase, M | 1 |
Ishida, T | 1 |
Kamei, C | 1 |
Wisor, JP | 1 |
Jiang, P | 1 |
Striz, M | 1 |
O'Hara, BF | 1 |
Morgan, PT | 1 |
Kehne, JH | 1 |
Sprenger, KJ | 1 |
Malison, RT | 1 |
Greenblatt, DJ | 3 |
Zammit, GK | 1 |
Noguchi, H | 1 |
Kitazumi, K | 1 |
Mori, M | 1 |
Shiba, T | 1 |
Kumar, A | 1 |
Kulkarni, SK | 1 |
Cotroneo, A | 1 |
Gareri, P | 1 |
Nicoletti, N | 1 |
Lacava, R | 1 |
Grassone, D | 1 |
Maina, E | 1 |
De Sarro, G | 1 |
Cabodi, S | 1 |
Poitras, R | 1 |
Pegram, V | 1 |
Hyde, P | 1 |
Linton, P | 1 |
Bentel, H | 1 |
Piccione, P | 1 |
Zorick, F | 9 |
Lutz, T | 2 |
Grissom, T | 1 |
Kramer, M | 2 |
Roth, T | 15 |
Venuti, A | 1 |
Saitta, FP | 1 |
Gioffrè Micali, M | 1 |
Giorgianni, G | 1 |
Micali, B | 1 |
Blumenthal, M | 1 |
Byring, R | 1 |
Koivula, K | 1 |
Pakes, GE | 1 |
Brogden, RN | 1 |
Heel, RC | 1 |
Speight, TM | 1 |
Avery, GS | 1 |
Sbarbaro, V | 1 |
Gambina, G | 1 |
Bovi, P | 1 |
Trabucco, G | 1 |
Signori, L | 1 |
Varricchio, MC | 1 |
Lingjaerde, O | 1 |
Bratlid, T | 1 |
Kudo, Y | 1 |
Cirignotta, F | 1 |
De Anna, M | 1 |
Mondini, S | 1 |
Baruzzi, A | 1 |
Dement, W | 3 |
Seidel, W | 3 |
Carskadon, M | 2 |
Muzet, A | 2 |
Johnson, LC | 3 |
Spinweber, CL | 3 |
Stepanski, E | 1 |
Kaffeman, M | 1 |
Sicklesteel, J | 1 |
Murphy, P | 1 |
Hindmarch, I | 2 |
Hyland, CM | 1 |
Carskadon, MA | 1 |
Seidel, WF | 5 |
Dement, WC | 6 |
Kales, A | 11 |
Soldatos, CR | 6 |
Bixler, EO | 7 |
Kales, JD | 6 |
Rickels, K | 1 |
Purpura, RP | 1 |
Dordain, G | 1 |
Puech, AJ | 1 |
Simon, P | 1 |
Macleod, N | 1 |
Ellingsen, PA | 1 |
Dehlin, O | 1 |
Björnson, G | 1 |
Fleming, JA | 3 |
Bliwise, D | 1 |
Karacan, I | 1 |
Mitler, M | 1 |
Boyd, DH | 1 |
Ankier, SI | 2 |
Costa E Silva, JA | 1 |
Acioli, A | 1 |
Naylor, C | 1 |
Jones Da Silva, C | 1 |
Ferreira, I | 1 |
Dahl, LE | 1 |
Dencker, SJ | 1 |
Lundin, L | 1 |
Kullingsjö, H | 1 |
Cohn, JB | 2 |
Di Perri, R | 1 |
Feldbaum, JS | 1 |
Libert, JP | 1 |
Weber, LD | 1 |
Amoros, C | 1 |
Ehrhart, J | 1 |
Follenius, M | 1 |
Oswald, I | 1 |
Nicholson, AN | 2 |
Ladewig, D | 1 |
Labrecque, G | 1 |
Hajak, G | 2 |
Clarenbach, P | 2 |
Fischer, W | 2 |
Haase, W | 1 |
Rüther, E | 2 |
Ando, K | 1 |
Hayakawa, T | 1 |
Ohta, T | 2 |
Kayukawa, Y | 1 |
Ito, A | 1 |
Iwata, T | 2 |
Okada, T | 2 |
Monti, JM | 1 |
Attali, P | 1 |
Monti, D | 1 |
Zipfel, A | 1 |
de la Giclais, B | 1 |
Morselli, PL | 1 |
Rosenberg, J | 1 |
Ahlstrøm, F | 1 |
Miyagawa, M | 1 |
Hayasaka, S | 1 |
Noda, S | 1 |
Landy, DA | 1 |
Fairweather, DB | 1 |
Rombaut, N | 1 |
O'Donovan, MC | 1 |
McGuffin, P | 1 |
Radecki, SE | 1 |
Brunton, SA | 1 |
Saletu, B | 1 |
Anderer, P | 1 |
Brandstätter, N | 1 |
Frey, R | 1 |
Grünberger, J | 1 |
Klösch, G | 1 |
Mandl, M | 1 |
Wetter, T | 1 |
Zeitlhofer, J | 1 |
Milby, JB | 2 |
Williams, V | 2 |
Hall, JN | 1 |
Khuder, S | 1 |
McGill, T | 1 |
Wooten, V | 2 |
Scharf, MB | 5 |
Terzano, MG | 2 |
Parrino, L | 2 |
Boselli, M | 2 |
Dell'Orso, S | 1 |
Moroni, M | 1 |
Spaggiari, MC | 2 |
Bourin, M | 1 |
Malinge, M | 1 |
Roehrs, T | 9 |
Pedrosi, B | 4 |
Rosenthal, L | 3 |
Rayón, P | 1 |
Serrano-Castro, M | 1 |
del Barrio, H | 1 |
Alvarez, C | 1 |
Montero, D | 1 |
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Kondo, T | 1 |
Kaneko, S | 1 |
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Mihara, K | 1 |
Morita, S | 1 |
Guthrie, SK | 1 |
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Walsh, JK | 2 |
Vogel, GW | 1 |
Lobo, BL | 2 |
Greene, WL | 2 |
Muzychenko, AP | 1 |
Prokudin, VN | 1 |
Bogdan, AN | 1 |
Smerieri, A | 1 |
Holt, RJ | 1 |
Allard, S | 1 |
Hauri, PJ | 1 |
Rodenbeck, A | 1 |
Bandelow, B | 1 |
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Azarnoff, DL | 1 |
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Gillin, JC | 2 |
Hullett, S | 1 |
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Stolley, PD | 1 |
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Pope, AM | 1 |
Klein, DF | 1 |
Dunner, DL | 1 |
Smirne, S | 1 |
Ferini-Strambi, L | 1 |
Usui, A | 1 |
Ishizuka, Y | 1 |
Matsushita, Y | 1 |
Fukuzawa, H | 1 |
Kanba, S | 2 |
Bonahoom, A | 2 |
Voderholzer, U | 1 |
Riemann, D | 1 |
Hornyak, M | 1 |
Backhaus, J | 1 |
Feige, B | 1 |
Berger, M | 1 |
Hohagen, F | 1 |
Kanda, T | 1 |
Yokosuka, O | 1 |
Fujiwara, K | 1 |
Saisho, H | 1 |
Shiga, H | 1 |
Oda, S | 1 |
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Sugawara, Y | 1 |
Makuuchi, M | 1 |
Hirasawa, H | 1 |
Fabre, LF | 5 |
Smith, WT | 1 |
Lomen, P | 1 |
Linet, OI | 1 |
McLendon, DM | 2 |
Harris, RT | 1 |
Gross, L | 1 |
Pasigajen, V | 1 |
Metzler, C | 2 |
Gainey, A | 1 |
Kemple, S | 1 |
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Slowe, IA | 1 |
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Mahowald, MW | 1 |
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Roehrs, TA | 1 |
Weingartner, HJ | 1 |
Eckardt, MJ | 1 |
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Reviews
16 reviews available for triazolam and Sleep Initiation and Maintenance Disorders
Article | Year |
---|---|
Triazolam: a review of its pharmacological properties and therapeutic efficacy in patients with insomnia.
Topics: Animals; Anti-Anxiety Agents; Clinical Trials as Topic; Cognition; Humans; Kinetics; Sleep Initiatio | 1981 |
Clinical trials of hypnotics.
Topics: Anti-Anxiety Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Flurazepam; Half-Li | 1983 |
Sleep laboratory studies of hypnotic drugs: efficacy and withdrawal effects.
Topics: Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Dose-Response Relationship, Drug; Fl | 1983 |
Rational basis for the use of sleeping pills.
Topics: Anxiety; Chronic Disease; Flurazepam; Humans; Hypnotics and Sedatives; Kinetics; Sleep; Sleep Initia | 1983 |
Issues in the diagnosis and treatment of insomnia.
Topics: Chronic Disease; Flurazepam; Humans; Hypnotics and Sedatives; Psychomotor Performance; Respiration; | 1984 |
Zolpidem: distinct from triazolam?
Topics: Humans; Hypnotics and Sedatives; Pyridines; Sleep Initiation and Maintenance Disorders; Triazolam; Z | 1997 |
Comparative clinical profiles of triazolam versus other shorter-acting hypnotics.
Topics: Azabicyclo Compounds; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Hypnotics | 1992 |
Review of triazolam data.
Topics: Age Factors; Aged; Clinical Trials as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Ph | 1992 |
Disinhibition, amnestic reactions, and other adverse reactions secondary to triazolam: a review of the literature.
Topics: Amnesia; Benzodiazepines; Delirium; Double-Blind Method; Humans; Placebos; Randomized Controlled Tri | 1992 |
A review of the safety profiles of benzodiazepine hypnotics.
Topics: Aged; Anti-Anxiety Agents; Benzodiazepines; Central Nervous System; Flurazepam; Half-Life; Humans; H | 1991 |
Benzodiazepine hypnotics and insomnia.
Topics: Anti-Anxiety Agents; Humans; Hypnotics and Sedatives; Psychotherapy; Sleep Initiation and Maintenanc | 1990 |
Rebound insomnia: a critical review.
Topics: Anti-Anxiety Agents; Flurazepam; Humans; Sleep Initiation and Maintenance Disorders; Sleep Stages; S | 1989 |
Relative abuse liability of triazolam: experimental assessment in animals and humans.
Topics: Amnesia; Animals; Anti-Anxiety Agents; Behavior, Animal; Discrimination, Psychological; Drug Interac | 1985 |
Rebound insomnia and elimination half-life: assessment of individual subject response.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Dose-Response Relationship, D | 1985 |
Loprazolam. A preliminary review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in insomnia.
Topics: Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Humans; Kinetics; Nitrazepam; Sleep; Sleep | 1986 |
Behavioral side effects of benzodiazepine hypnotics.
Topics: Amnesia; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Flurazepam; Humans; Hypnotics and Sedatives; | 1985 |
Trials
76 trials available for triazolam and Sleep Initiation and Maintenance Disorders
Article | Year |
---|---|
Effects of different doses of triazolam in the middle-of-the-night insomnia: a double-blind, randomized, parallel group study.
Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypnotics and Sedative | 2017 |
Chronic use of triazolam: the effects on the sleep patterns of insomniacs.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Human | 1980 |
A comparative study between two new benzodiazepine hypnotics.
Topics: Adult; Anti-Anxiety Agents; Female; Flunitrazepam; Humans; Male; Middle Aged; Preoperative Care; Sle | 1980 |
The efficacy of triazolam and chloral hydrate in geriatric insomniacs.
Topics: Aged; Anti-Anxiety Agents; Chloral Hydrate; Clinical Trials as Topic; Double-Blind Method; Humans; M | 1980 |
[Triazolam in the treatment of presurgical patients].
Topics: Adult; Anti-Anxiety Agents; Female; Humans; Male; Middle Aged; Preoperative Care; Sleep; Sleep Initi | 1980 |
Comparison of nitrazepam 5 mg with triazolam 0.5 mg in young psychiatric insomniac inpatients. Double-blind single night cross-over study.
Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Humans; Male; Nitrazepam; | 1980 |
Triazolam: a review of its pharmacological properties and therapeutic efficacy in patients with insomnia.
Topics: Animals; Anti-Anxiety Agents; Clinical Trials as Topic; Cognition; Humans; Kinetics; Sleep Initiatio | 1981 |
[Experimental double-blind study of triazolam versus placebo].
Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Placebos; S | 1981 |
Triazolam (Halcion) versus flunitrazepam (Rohypnol) against midwinter insomnia in Northern Norway.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Fluni | 1981 |
Aspects of short-term use of two benzodiazepine hypnotics in the elderly.
Topics: Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind | 1982 |
Daytime carryover of triazolam and flurazepam in elderly insomniacs.
Topics: Aged; Anti-Anxiety Agents; Arousal; Clinical Trials as Topic; Emotions; Female; Flurazepam; Humans; | 1982 |
Clinical trials of hypnotics.
Topics: Anti-Anxiety Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Flurazepam; Half-Li | 1983 |
Approaches in the evaluation of hypnotics: studies with triazolam.
Topics: Anti-Anxiety Agents; Clinical Trials as Topic; Hospitalization; Humans; Psychomotor Performance; Sle | 1981 |
A clinical trial of a new hypnotic--loprazolam.
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Clinical Trials as Topic; Fema | 1983 |
Midazolam and triazolam in out-patients: a double-blind comparison of hypnotic efficacy.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Female; | 1983 |
Comparison of nitrazepam with triazolam in insomniac outpatients.
Topics: Adult; Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Mal | 1982 |
Triazolam treatment of insomnia in depressed patients taking tricyclics.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive D | 1983 |
Double-blind crossover comparison of triazolam and lorazepam in the posthypnotic state.
Topics: Adolescent; Adult; Akathisia, Drug-Induced; Anti-Anxiety Agents; Clinical Trials as Topic; Dizziness | 1984 |
Influence of triazolam on thermal heat balance in poor sleepers.
Topics: Adult; Anti-Anxiety Agents; Body Temperature; Body Temperature Regulation; Catecholamines; Dopamine; | 1984 |
Zopiclone improves sleep quality and daytime well-being in insomniac patients: comparison with triazolam, flunitrazepam and placebo.
Topics: Azabicyclo Compounds; Double-Blind Method; Female; Flunitrazepam; Humans; Male; Middle Aged; Piperaz | 1994 |
Zolpidem and rebound insomnia--a double-blind, controlled polysomnographic study in chronic insomniac patients.
Topics: Adult; Aged; Anxiety; Chronic Disease; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; | 1994 |
Randomized, double blind trial of zolpidem 10 mg versus triazolam 0.25 mg for treatment of insomnia in general practice.
Topics: Adult; Aged; Circadian Rhythm; Double-Blind Method; Family Practice; Female; Humans; Hypnotics and S | 1994 |
Insomnia in generalized anxiety disorder: polysomnographic, psychometric and clinical investigations before, during and after therapy with a long- versus a short-half-life benzodiazepine (quazepam versus triazolam).
Topics: Adult; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Double-Blind Method; Female; Humans; Hypnotics | 1994 |
Effectiveness of combined triazolam-behavioral therapy for primary insomnia.
Topics: Adult; Behavior Therapy; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Male; Placebo | 1993 |
Feasibility of an every-other-night regimen in insomniac patients: subjective hypnotic effectiveness of quazepam, triazolam, and placebo.
Topics: Anti-Anxiety Agents; Benzodiazepines; Circadian Rhythm; Double-Blind Method; Drug Administration Sch | 1993 |
Changes of cyclic alternating pattern (CAP) parameters in situational insomnia under brotizolam and triazolam.
Topics: Adult; Animals; Azepines; Cricetinae; Electroencephalography; Female; Humans; Hypnotics and Sedative | 1995 |
A new design of trial for hypnotics comparison: a double-blind cross-over trial with patient's preference assessment and continuation of the preferred treatment.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Female; Humans; Male; Middle Aged; S | 1996 |
Hypnotic self administration and dose escalation.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middl | 1996 |
Triazolam and diphenhydramine effects on seizure duration in depressed patients receiving ECT.
Topics: Adult; Aged; Depressive Disorder; Diphenhydramine; Electroconvulsive Therapy; Electroencephalography | 1996 |
Minimal rebound insomnia after treatment with 10-mg zolpidem.
Topics: Adult; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Polysomnogra | 1997 |
[Halcion (triazolam) in the treatment of insomnia].
Topics: Adult; Chronic Disease; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Sleep Initiation | 1997 |
Multidrug comparison (lorazepam, triazolam, zolpidem, and zopiclone) in situational insomnia: polysomnographic analysis by means of the cyclic alternating pattern.
Topics: Adult; Azabicyclo Compounds; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; | 1997 |
Hypnotic self administration: forced-choice versus single-choice.
Topics: Adult; Affect; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Self | 1997 |
Can we mix behavioral therapy with hypnotics when treating insomniacs?
Topics: Adult; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; Male; | 1997 |
Rebound insomnia after hypnotic withdrawal in insomniac outpatients.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Anxiety Agents; Azabicyclo Compounds; Double-Bli | 1998 |
Clinical applications of cyclic alternating pattern.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anticonvulsants; Electroencephalography; GABA Modulators; | 1999 |
Bright light treatment for night-time insomnia and daytime sleepiness in elderly people: comparison with a short-acting hypnotic.
Topics: Aged; Aged, 80 and over; Cross-Over Studies; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pho | 2000 |
Treatment regimen and hypnotic self-administration.
Topics: Adult; Analysis of Variance; Anti-Anxiety Agents; Capsules; Female; Humans; Hypnotics and Sedatives; | 2001 |
A double-blind, randomized and placebo-controlled study on the polysomnographic withdrawal effects of zopiclone, zolpidem and triazolam in healthy subjects.
Topics: Adult; Azabicyclo Compounds; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalo | 2001 |
Nighttime versus daytime hypnotic self-administration.
Topics: Adult; Analysis of Variance; Anti-Anxiety Agents; Circadian Rhythm; Double-Blind Method; Female; Hum | 2002 |
Multi-clinic cross-over comparison of triazolam (Halcion) and placebo in the treatment of co-existing insomnia and anxiety in anxious out-patients.
Topics: Adolescent; Adult; Ambulatory Care; Anti-Anxiety Agents; Anxiety; Drug Evaluation; Female; Humans; M | 1977 |
Hypnotic efficacy of triazolam and methyprylon ininsomniac in-patients.
Topics: Adult; Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Female; Humans; Hypnotics and Sedatives; | 1976 |
Intermediate use of triazolam: a sleep laboratory study.
Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Electroencephalography; Electromyography; Elec | 1976 |
Preference studies of triazolam with standard hypnotics in out-patients with insomnia.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Chloral Hydrate; Clinical Trials as Topic; Double-Blin | 1976 |
Multiclinic double-blind comparison of triazolam and flurazepam for seven nights in outpatients with insomnia.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Drug Ev | 1977 |
Multi-clinic double-blind comparison of triazolam (Halcion) and placebo administered for 14 consecutive nights in outpatients with insomnia.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Humans; Middl | 1978 |
A clinical comparison of triazolam with placebo and with secobarbital in insomniac patients.
Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Mid | 1978 |
Comparative efficacy of triazolam, flurazepam and placebo in out-patients insomniacs.
Topics: Adult; Anti-Anxiety Agents; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; | 1978 |
Methodology for demonstrating sustained efficacy of hypnotics: a comparative study of triazolam and flurazepam.
Topics: Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Flurazepam; Humans; Middl | 1979 |
Model insomnia, noise, and methylphenidate, used for the evaluation of hypnotic drugs.
Topics: Adult; Drug Evaluation; Electroencephalography; Flurazepam; Humans; Hypnotics and Sedatives; Male; M | 1978 |
A double-blind comparison of the effects of temazepam and triazolam on residual, daytime performance in elderly insomniacs.
Topics: Aged; Cognition; Double-Blind Method; Female; Geriatric Assessment; Humans; Male; Neuropsychological | 1992 |
Rebound insomnia in normals and patients with insomnia after abrupt and tapered discontinuation.
Topics: Adult; Double-Blind Method; Female; Humans; Male; Middle Aged; Sleep Initiation and Maintenance Diso | 1992 |
Rebound insomnia and hypnotic self administration.
Topics: Adult; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Self Adminis | 1992 |
Next-day memory impairment with triazolam use.
Topics: Activities of Daily Living; Adolescent; Adult; Amnesia, Retrograde; Capsules; Double-Blind Method; D | 1991 |
Rebound insomnia: duration of use and individual differences.
Topics: Adult; Drug Tolerance; Electroencephalography; Humans; Male; Monitoring, Physiologic; Sleep Initiati | 1991 |
Efficacy of behavioral versus triazolam treatment in persistent sleep-onset insomnia.
Topics: Adult; Behavior Therapy; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Male; Perso | 1991 |
Rebound insomnia after only brief and intermittent use of rapidly eliminated benzodiazepines.
Topics: Adult; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Random Allocation; Sleep Initiati | 1991 |
A comparative study of zopiclone and triazolam in patients with insomnia.
Topics: Adult; Aged; Arousal; Azabicyclo Compounds; Double-Blind Method; Female; Humans; Hypnotics and Sedat | 1990 |
A comparison of the efficacy, safety and withdrawal effects of zopiclone and triazolam in the treatment of insomnia.
Topics: Adolescent; Adult; Azabicyclo Compounds; Double-Blind Method; Female; Humans; Hypnotics and Sedative | 1990 |
Efficacy and safety of zopiclone and triazolam in the treatment of geriatric insomniacs.
Topics: Aged; Aged, 80 and over; Arousal; Azabicyclo Compounds; Dose-Response Relationship, Drug; Double-Bli | 1990 |
Zopiclone versus triazolam in insomniac geriatric patients: a specific increase in delta sleep with zopiclone.
Topics: Aged; Aged, 80 and over; Arousal; Azabicyclo Compounds; Delta Rhythm; Double-Blind Method; Electroen | 1990 |
Zopiclone and triazolam in insomnia associated with generalized anxiety disorder: a placebo-controlled evaluation of efficacy and daytime anxiety.
Topics: Adult; Anxiety Disorders; Azabicyclo Compounds; Drug Administration Schedule; Female; Humans; Hypnot | 1990 |
The effects of a single night's dosing with triazolam on sleep the following night.
Topics: Adult; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Random Allocation; Sleep | 1990 |
Rebound insomnia and elimination half-life: assessment of individual subject response.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Dose-Response Relationship, D | 1985 |
Early morning insomnia and daytime anxiety--a multicentre general practice study comparing loprazolam and triazolam.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; | 1985 |
Buspirone: an anxiolytic without sedative effect.
Topics: Adult; Anti-Anxiety Agents; Buspirone; Chronic Disease; Clinical Trials as Topic; Double-Blind Metho | 1985 |
Comparative amnestic effects of benzodiazepine hypnotic agents.
Topics: Adult; Amnesia; Anti-Anxiety Agents; Dose-Response Relationship, Drug; Humans; Memory, Short-Term; M | 1988 |
Profile of mood states changes during and after 5 weeks of nightly triazolam administration.
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; MMPI; | 1988 |
Effect of triazolam on sleep and arterial oxygen saturation in patients with chronic obstructive pulmonary disease.
Topics: Aged; Double-Blind Method; Female; Humans; Hypercapnia; Hypoxia; Lung Diseases, Obstructive; Male; M | 1988 |
Comparison of the short-acting benzodiazepines midazolam and triazolam with placebo.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Dreams; Female; Humans; Male; Midazolam; | 1988 |
Effect of gradual withdrawal on the rebound sleep disorder after discontinuation of triazolam.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Female; Humans; | 1987 |
Behavioral side effects of triazolam in psychiatric inpatients: report of five cases.
Topics: Adult; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Hospitalization; Humans; M | 1986 |
A double-blind controlled study of chlormethiazole and triazolam as hypnotics in the elderly.
Topics: Aged; Arousal; Chlormethiazole; Clinical Trials as Topic; Double-Blind Method; Female; Flicker Fusio | 1986 |
Comparison of short and long half-life benzodiazepine hypnotics: triazolam and quazepam.
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Dr | 1986 |
Comparison of the clinical hypnotic effects of zopiclone and triazolam.
Topics: Adult; Azabicyclo Compounds; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypnotic | 1987 |
Dose-related effects of triazolam and flurazepam on a circadian rhythm insomnia.
Topics: Adult; Circadian Rhythm; Dose-Response Relationship, Drug; Double-Blind Method; Flurazepam; Humans; | 1986 |
Other Studies
81 other studies available for triazolam and Sleep Initiation and Maintenance Disorders
Article | Year |
---|---|
Outdoor Artificial Nighttime Light and Use of Hypnotic Medications in Older Adults: A Population-Based Cohort Study.
Topics: Age Factors; Aged; Cohort Studies; Drug Utilization Review; Female; Humans; Hypnotics and Sedatives; | 2018 |
Quantification of adverse effects of regular use of triazolam on clinical outcomes for older people with insomnia: a retrospective cohort study.
Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Female; Humans; Hypnotics and Sedatives; Japan; Male; | 2016 |
Rebound insomnia induced by abrupt withdrawal of hypnotics in sleep-disturbed rats.
Topics: Animals; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Sch | 2008 |
Effects of ramelteon and triazolam in a mouse genetic model of early morning awakenings.
Topics: Animals; Circadian Rhythm; Darkness; Disease Models, Animal; Indenes; Locomotion; Male; Mice; Mice, | 2009 |
Retrograde effects of triazolam and zolpidem on sleep-dependent motor learning in humans.
Topics: Adult; Arousal; Cognition Disorders; Disorders of Excessive Somnolence; Dose-Response Relationship, | 2010 |
Pharmacokinetic evaluation of eszopiclone: clinical and therapeutic implications.
Topics: Acetamides; Adult; Aged; Azabicyclo Compounds; Clinical Trials as Topic; Cytochrome P-450 CYP3A; Cyt | 2012 |
Electroencephalographic properties of zaleplon, a non-benzodiazepine sedative/hypnotic, in rats.
Topics: Acetamides; Administration, Oral; Animals; Azabicyclo Compounds; Cerebral Cortex; Dose-Response Rela | 2004 |
On the sleep promoting effects of BR-16A: interaction with GABAergic modulators.
Topics: Alprazolam; Animals; Dose-Response Relationship, Drug; Drug Interactions; Female; GABA Agonists; GAB | 2004 |
Effectiveness and safety of hypnotic drugs in the treatment of insomnia in over 70-year old people.
Topics: Aged; Cognition Disorders; Dementia; Depression; Drug Administration Schedule; Female; Health Status | 2007 |
[Therapy of insomnia].
Topics: Anti-Anxiety Agents; Drug Evaluation; Humans; Placebos; Sleep Initiation and Maintenance Disorders; | 1980 |
[Episodes of anterograde amnesia associated with the use of triazolam].
Topics: Adult; Amnesia; Anti-Anxiety Agents; Female; Humans; Male; Middle Aged; Sleep Initiation and Mainten | 1980 |
Hypnotic effects of a benzodiazepine derivative: a clinical observation.
Topics: Adult; Aged; Ambulatory Care; Anti-Anxiety Agents; Double-Blind Method; Female; Hospitalization; Hum | 1982 |
[Evaluation of the hypnotic activity of triazolam in comparison with flunitrazepam].
Topics: Adult; Aged; Anti-Anxiety Agents; Female; Flunitrazepam; Humans; Male; Middle Aged; Sleep Initiation | 1982 |
Daytime alertness, insomnia, and benzodiazepines.
Topics: Adult; Anti-Anxiety Agents; Arousal; Benzodiazepines; Double-Blind Method; Flurazepam; Humans; Loraz | 1982 |
Benzodiazepine hypnotics increase heart rate during sleep.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Flurazepam; Heart Rate; Humans; Male; Sleep; Sleep | 1982 |
[Effects of the chronic administration of triazolam 0.50 mg on the sleep of insomniacs].
Topics: Adult; Anti-Anxiety Agents; Drug Evaluation; Female; Humans; Male; Middle Aged; Sleep; Sleep Initiat | 1982 |
Triazolam--a new benzodiazepine for insomnia.
Topics: Anti-Anxiety Agents; Humans; Sleep Initiation and Maintenance Disorders; Triazolam | 1983 |
Early morning insomnia with rapidly eliminated benzodiazepines.
Topics: Anti-Anxiety Agents; Benzodiazepines; Flurazepam; Half-Life; Humans; Midazolam; Sleep; Sleep Initiat | 1983 |
Triazolam compared with nitrazepam and with oxazepam in insomnia: two double-blind, crossover studies analyzed sequentially.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Double-Blind Method; Female; Humans; Male; Middle Aged | 1981 |
Triazolam: monitored release in the United Kingdom.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Child; Female; Humans; Male; Middle Aged; Sleep Initia | 1981 |
Double-blind trial of triazolam 0.5 mg vs. nitrazepam 5 mg in outpatients.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Arousal; Double-Blind Method; Female; Humans; Male; Middle A | 1983 |
Triazolam as a hypnotic for geriatric patients. A double-blind cross-over comparison of nitrazepam and triazolam regarding effects on sleep and psychomotor performance.
Topics: Aged; Anti-Anxiety Agents; Double-Blind Method; Female; Humans; Male; Motor Skills; Nitrazepam; Slee | 1983 |
Triazolam abuse.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Humans; Male; Sleep Initiation and Maintenance Disorders; Su | 1983 |
Daytime sleepiness as a criterion in hypnotic medication trials: comparison of triazolam and flurazepam.
Topics: Adult; Anti-Anxiety Agents; Arousal; Double-Blind Method; Female; Flurazepam; Humans; Male; Sleep In | 1983 |
[Our electroencephalographic data in the framework of a review on lormetazepam].
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Electroencephalography; Female; Humans; Lorazepam | 1984 |
Inadvertent benzodiazepine withdrawal.
Topics: Anti-Anxiety Agents; Flurazepam; Humans; Male; Middle Aged; Sleep Initiation and Maintenance Disorde | 1984 |
Sleep spindle and delta changes during chronic use of a short-acting and a long-acting benzodiazepine hypnotic.
Topics: Adult; Anti-Anxiety Agents; Brain; Double-Blind Method; Electroencephalography; Female; Flurazepam; | 1983 |
Studies with modern hypnotics.
Topics: Anxiety; Benzodiazepines; Humans; Hypnotics and Sedatives; Sleep Initiation and Maintenance Disorder | 1984 |
Hypnotics: rebound insomnia and residual sequelae.
Topics: Humans; Hypnotics and Sedatives; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Sy | 1980 |
[Does a rebound insomnia following benzodiazepine administration exist?].
Topics: Benzodiazepines; Diazepam; Flunitrazepam; Flurazepam; Humans; Nitrazepam; Sleep Initiation and Maint | 1980 |
[Between the two...].
Topics: Aged; Flurazepam; Humans; Hypnotics and Sedatives; Sleep; Sleep Initiation and Maintenance Disorders | 1980 |
Long-term follow-up study of 10 adolescent patients with sleep-wake schedule disorders.
Topics: Adolescent; Behavior Therapy; Circadian Rhythm; Combined Modality Therapy; Female; Follow-Up Studies | 1994 |
Photic maculopathy resulting from the light of a video camera in patients taking triazolam.
Topics: Female; Humans; Light; Macula Lutea; Male; Middle Aged; Pupil; Radiation Injuries; Retinal Diseases; | 1994 |
Article questioned.
Topics: Anti-Anxiety Agents; Benzodiazepines; Humans; Peer Review; Periodicals as Topic; Placebos; Research | 1994 |
Adverse events after triazolam substitution.
Topics: Aged; Anti-Anxiety Agents; Female; Humans; Male; Retrospective Studies; Sleep Initiation and Mainten | 1993 |
Short acting benzodiazepines.
Topics: Amnesia; Anti-Anxiety Agents; Anxiety; Depression; Half-Life; Humans; Sleep Initiation and Maintenan | 1993 |
Management of insomnia in office-based practice. National prevalence and therapeutic patterns.
Topics: Adolescent; Adult; Aged; Data Collection; Female; Flurazepam; Humans; Male; Medicine; Middle Aged; P | 1993 |
Hypnotic drug use in Spain: a cross-sectional study based on a network of community pharmacies. Spanish Group for the Study of Hypnotic Drug Utilization.
Topics: Administration, Oral; Aged; Dose-Response Relationship, Drug; Drug and Narcotic Control; Female; Hum | 1996 |
Hallucinations after a therapeutic dose of benzodiazepine hypnotics with co-administration of erythromycin.
Topics: Anti-Anxiety Agents; Drug Therapy, Combination; Erythromycin; Hallucinations; Humans; Kidney Failure | 1996 |
Insomnia.
Topics: Humans; Hypnotics and Sedatives; Pyridines; Sleep Initiation and Maintenance Disorders; Triazolam; Z | 1997 |
Comment: zolpidem: distinct from triazolam?
Topics: Humans; Hypnotics and Sedatives; Pyridines; Sleep Initiation and Maintenance Disorders; Triazolam; Z | 1997 |
Report of the Institute of Medicine Committee on the Efficacy and Safety of Halcion.
Topics: Adverse Drug Reaction Reporting Systems; Chronic Disease; Drug Approval; Drug Evaluation; Evaluation | 1999 |
The report by the Institute of Medicine and postmarketing surveillance.
Topics: Clinical Trials as Topic; Drug Approval; Evaluation Studies as Topic; Humans; Hypnotics and Sedative | 1999 |
Long-term use of sedative and hypnotic medication.
Topics: Drug Approval; Evaluation Studies as Topic; Humans; Hypnotics and Sedatives; National Academies of S | 1999 |
Fulminant hepatic failure associated with triazolam.
Topics: Anti-Anxiety Agents; Female; Humans; Liver Failure; Middle Aged; Sleep Initiation and Maintenance Di | 2002 |
Pilot open-label study of triazolam in the treatment of insomnia following alcohol withdrawal.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Anxiety; Drug Evaluation; Female; Humans; Male; Middle Aged; | 1977 |
[Comparison of the hypnotic activity of triazolam and flurazepam].
Topics: Adult; Anti-Anxiety Agents; Evaluation Studies as Topic; Female; Flurazepam; Humans; Male; Middle Ag | 1979 |
Hypnotics today.
Topics: Aged; Anti-Anxiety Agents; Diazepam; Electroencephalography; Humans; Sleep; Sleep Initiation and Mai | 1979 |
Two more benzodiazepines.
Topics: Anti-Anxiety Agents; Anxiety; Benzodiazepinones; Humans; Sleep Initiation and Maintenance Disorders; | 1979 |
Rebound insomnia. A potential hazard following withdrawal of certain benzodiazepines.
Topics: Acute Disease; Benzodiazepines; Flunitrazepam; Half-Life; Humans; Nitrazepam; Sleep Initiation and M | 1979 |
Rebound insomnia: a new clinical syndrome.
Topics: Benzodiazepines; Brain; Flunitrazepam; Humans; Hypnotics and Sedatives; Nitrazepam; Receptors, Drug; | 1978 |
New labeling and patient insert for triazolam approved by FDA.
Topics: Drug Labeling; Humans; Sleep Initiation and Maintenance Disorders; Triazolam; United States; United | 1992 |
Clinical uses and advantages of low doses of benzodiazepine hypnotics.
Topics: Adult; Aged; Amnesia; Benzodiazepines; Dose-Response Relationship, Drug; Drug Administration Schedul | 1992 |
Diagnosis and treatment of outpatient insomnia by psychiatric and nonpsychiatric physicians.
Topics: Disease; Drug Prescriptions; Drug Utilization; Female; Flurazepam; General Surgery; Humans; Internal | 1992 |
Triazolam-induced nocturnal bingeing with amnesia.
Topics: Amnesia; Female; Humans; Hyperphagia; Middle Aged; Obesity; Sleep Initiation and Maintenance Disorde | 1992 |
Triazolam accumulation in the elderly after prolonged use.
Topics: Adult; Aged; Aged, 80 and over; Female; Half-Life; Humans; Male; Middle Aged; Radioligand Assay; Rec | 1991 |
Avoiding the blanket approach to insomnia. Targeted therapy for specific causes.
Topics: Anti-Anxiety Agents; Benzodiazepines; Chronic Disease; Diagnosis, Differential; Estazolam; Flurazepa | 1991 |
Nocturnal wandering caused by restless legs and short-acting benzodiazepines.
Topics: Anti-Anxiety Agents; Benserazide; Drug Therapy, Combination; Humans; Levodopa; Male; Middle Aged; My | 1991 |
Specificity of memory impairments with triazolam use.
Topics: Benzodiazepines; Dose-Response Relationship, Drug; Humans; Memory Disorders; Memory, Short-Term; Sle | 1991 |
Triazolam--the never-ending story.
Topics: Amnesia; Delirium; Humans; Sleep Initiation and Maintenance Disorders; Triazolam | 1991 |
Triazolam side effects in parkinsonism.
Topics: Aged; Delirium; Female; Humans; Male; Parkinson Disease; Sleep Initiation and Maintenance Disorders; | 1991 |
The beneficial and adverse effects of hypnotics.
Topics: Adolescent; Adult; Aged; Attitude to Health; Benzodiazepines; Data Collection; Drug Prescriptions; E | 1991 |
Diagnosis and management of insomnia.
Topics: Humans; Sleep Initiation and Maintenance Disorders; Triazolam | 1990 |
Motor phenomena in benzodiazepine withdrawal.
Topics: Aged; Alprazolam; Anti-Anxiety Agents; Diagnosis, Differential; Diazepam; Drug Therapy, Combination; | 1989 |
Evaluation of long-term triazolam use in an ambulatory Veterans Administration Medical Center population.
Topics: Drug Prescriptions; Drug Tolerance; Evaluation Studies as Topic; Hospitals, Veterans; Humans; Middle | 1989 |
A treatment trial of delayed sleep phase syndrome with triazolam.
Topics: Adult; Arousal; Circadian Rhythm; Depressive Disorder; Dose-Response Relationship, Drug; Drug Admini | 1989 |
Comment: long-term triazolam use.
Topics: Aged; Humans; Hypnotics and Sedatives; Sleep Initiation and Maintenance Disorders; Triazolam | 1989 |
Putting benzodiazepine hypnotics into proper therapeutic perspective.
Topics: Anti-Anxiety Agents; Flurazepam; Humans; Sleep Initiation and Maintenance Disorders; Temazepam; Tria | 1985 |
Coma caused by trivial triazolam overdose.
Topics: Adult; Anti-Anxiety Agents; Coma; Female; Headache; Humans; Sleep Initiation and Maintenance Disorde | 1985 |
Early morning insomnia, daytime anxiety, and organic mental disorder associated with triazolam.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Humans; Male; Sleep Initiation and Maintenance Disorders; Subst | 1985 |
Agitation observed during treatment with newer hypnotic drugs.
Topics: Adult; Aged; Akathisia, Drug-Induced; Anger; Anti-Anxiety Agents; Female; Half-Life; Hostility; Huma | 1985 |
[Efficacy and tolerance of triazolam compared with flurazepam in patients with insomnia].
Topics: Adolescent; Adult; Anti-Anxiety Agents; Drug Tolerance; Female; Flurazepam; Humans; Male; Middle Age | 1985 |
The use of benzodiazepines with particular reference to the elderly.
Topics: Aged; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Diazepam; Humans; Infusions, Parenteral; Kinet | 1986 |
[Controlled clinical evaluation of 2 hypnotic triazole benzodiazepines, estazolam and triazolam, used the night before surgical interventions].
Topics: Adult; Anti-Anxiety Agents; Estazolam; Female; Humans; Male; Middle Aged; Premedication; Sleep; Slee | 1987 |
The use of benzodiazepine hypnotics in the elderly.
Topics: Adolescent; Age Factors; Aged; Aged, 80 and over; Canada; Drug Interactions; Drug Prescriptions; Dru | 1988 |
Involuntary self-intoxication with triazolam.
Topics: Crime; Humans; Male; Middle Aged; Psychoses, Substance-Induced; Sleep Initiation and Maintenance Dis | 1987 |
Manipulation of a central circadian clock regulating behavioral and endocrine rhythms with a short-acting benzodiazepine used in the treatment of insomnia.
Topics: Animals; Circadian Rhythm; Cricetinae; Dark Adaptation; Dose-Response Relationship, Drug; Female; Lu | 1988 |
Update on hypnotics for insomnia in clinical practice: I. Hypnotics.
Topics: Adult; Humans; Hypnotics and Sedatives; Sleep Initiation and Maintenance Disorders; Temazepam; Triaz | 1986 |
Withdrawal regimen for triazolam-dependent patients.
Topics: Diazepam; Flurazepam; Humans; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndr | 1986 |
Effects of quazepam and triazolam on the sleep of chronic insomniacs: a comparative 25-night sleep laboratory study.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Chronic Disease; Drug Tolerance; Female; Humans; Male; | 1985 |
Efficacy of a reduced triazolam dose in elderly insomniacs.
Topics: Aged; Female; Humans; Male; Middle Aged; Sleep Initiation and Maintenance Disorders; Triazolam | 1985 |