triazolam has been researched along with Pregnancy in 10 studies
Triazolam: A short-acting benzodiazepine used in the treatment of insomnia. Some countries temporarily withdrew triazolam from the market because of concerns about adverse reactions, mostly psychological, associated with higher dose ranges. Its use at lower doses with appropriate care and labeling has been reaffirmed by the FDA and most other countries.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Triazolam was shown to have a pronounced amnesic effect and whilst it might be used for premedication, its lack of anxiolysis coupled with a significant impairment of psychomotor performance at 3 hours after awakening, render the drug unsuitable for premedication in the short stay patient." | 2.66 | A comparison of triazolam and diazepam as premedication agents for minor gynaecological surgery. ( Fell, D; Hunt, PC; Miller, R; Pinnock, CA; Smith, G, 1985) |
| "Triazolam has not been shown to be carcinogenic, and it has a low potential for abuse and addiction." | 2.42 | Oral triazolam sedation in implant dentistry. ( Flanagan, D, 2004) |
| "Triazolam, which is a substrate of Cyp3a, was intraperitoneally administered to the mice in the HF group." | 1.38 | Consumption of a high-fat diet during pregnancy decreases the activity of cytochrome P450 3a in the livers of offspring. ( Ikarashi, N; Imahori, Y; Ishii, M; Kon, R; Kusunoki, Y; Ochiai, W; Okaniwa, T; Saruta, K; Sugiyama, K; Tajima, M; Toda, T; Yamada, H, 2012) |
| "Triazolam failed to produce statistically significant phase shifts when administered during the subjective day, but 2 animals bearing functional SCN grafts responded to this benzodiazapine during the subjective night." | 1.29 | Regulation of the phase and period of circadian rhythms restored by suprachiasmatic transplants. ( Basil, J; Bittman, EL; Jetton, AE; Lehman, MN; Matsumoto, S, 1996) |
| "gamma-Aminobutyric acid (GABA) acts as an inhibitory transmitter in the vertebrate central nervous system, often by interacting with the GABAA type of receptor." | 1.28 | Activation and inactivation of the GABAA receptor: insights from comparison of native and recombinant subunit assemblies. ( Mathers, DA, 1991) |
| " and 1 h after oral dosing of [14C]triazolam to rats." | 1.26 | Metabolism of 8-chloro-6-(o-chlorophenyl)-1-methyl-4H-s-triazolo [4,3-alpha] [1,4] benzodiazepine, triazolam, a new central depressant. I. Absorption, distribution and excretion in rats, dogs and monkeys. ( Esumi, Y; Kitagawa, H; Kurosawa, S; Sekine, S; Yokoshima, T, 1979) |
| " Major metabolites in the urine, faeces, plasma and brain after 7-, 14- or 21-day repeated dosing in rats were not much different in type and ratio from those after single dosing." | 1.26 | Metabolism of 8-chloro-6-(o-chlorophenyl)-1-methyl-4H-s-triazolo [4,3-alpha] [1,4]benzodiazepine, triazolam, a new central depressant. II. Identification and determination of metabolites in rats and dogs. ( Esumi, Y; Kitagawa, H; Kurosawa, S; Sekine, S; Yokoshima, T, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tajima, M | 1 |
| Ikarashi, N | 1 |
| Imahori, Y | 1 |
| Okaniwa, T | 1 |
| Saruta, K | 1 |
| Ishii, M | 1 |
| Kusunoki, Y | 1 |
| Kon, R | 1 |
| Toda, T | 1 |
| Ochiai, W | 1 |
| Yamada, H | 1 |
| Sugiyama, K | 1 |
| Flanagan, D | 1 |
| Matsumoto, S | 1 |
| Basil, J | 1 |
| Jetton, AE | 1 |
| Lehman, MN | 1 |
| Bittman, EL | 1 |
| Sakai, T | 1 |
| Matsuda, H | 1 |
| Watanabe, N | 1 |
| Kitagawa, H | 2 |
| Esumi, Y | 2 |
| Kurosawa, S | 2 |
| Sekine, S | 2 |
| Yokoshima, T | 2 |
| Mathers, DA | 1 |
| Ved, HS | 1 |
| Gustow, E | 1 |
| Pieringer, RA | 1 |
| Pinnock, CA | 1 |
| Fell, D | 1 |
| Hunt, PC | 1 |
| Miller, R | 1 |
| Smith, G | 1 |
| Attallah, A | 1 |
| Seilanian, M | 1 |
| Bavoux, F | 1 |
| Choisy, H | 1 |
1 review available for triazolam and Pregnancy
| Article | Year |
|---|---|
Oral triazolam sedation in implant dentistry.
Topics: Administration, Oral; Anesthesia, Dental; Conscious Sedation; Contraindications; Dental Implants; Fe | 2004 |
1 trial available for triazolam and Pregnancy
| Article | Year |
|---|---|
A comparison of triazolam and diazepam as premedication agents for minor gynaecological surgery.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female | 1985 |
8 other studies available for triazolam and Pregnancy
| Article | Year |
|---|---|
Consumption of a high-fat diet during pregnancy decreases the activity of cytochrome P450 3a in the livers of offspring.
Topics: Animals; Animals, Newborn; Area Under Curve; Blood Glucose; Body Weight; Cytochrome P-450 CYP3A; Die | 2012 |
Regulation of the phase and period of circadian rhythms restored by suprachiasmatic transplants.
Topics: Animals; Brain Tissue Transplantation; Circadian Rhythm; Cricetinae; Female; Fetal Tissue Transplant | 1996 |
Triazolam (Halcion) intoxication in a neonate--a first report.
Topics: Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Infant, Premature; Maternal Exposure; Pois | 1996 |
Metabolism of 8-chloro-6-(o-chlorophenyl)-1-methyl-4H-s-triazolo [4,3-alpha] [1,4] benzodiazepine, triazolam, a new central depressant. I. Absorption, distribution and excretion in rats, dogs and monkeys.
Topics: Animals; Anti-Anxiety Agents; Autoradiography; Blood Proteins; Dogs; Female; Haplorhini; Injections, | 1979 |
Metabolism of 8-chloro-6-(o-chlorophenyl)-1-methyl-4H-s-triazolo [4,3-alpha] [1,4]benzodiazepine, triazolam, a new central depressant. II. Identification and determination of metabolites in rats and dogs.
Topics: Animals; Anti-Anxiety Agents; Benzophenones; Bile; Brain; Dogs; Feces; Female; Fetus; Male; Maternal | 1979 |
Activation and inactivation of the GABAA receptor: insights from comparison of native and recombinant subunit assemblies.
Topics: Animals; Female; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Mice; Neurons; Pregnancy | 1991 |
Regulation of neuronal differentiation in neuron-enriched primary cultures from embryonic rat cerebra by platelet activating factor and the structurally related glycerol ether lipid, dodecylglycerol.
Topics: Acetylcholinesterase; Animals; Brain; Cell Differentiation; Cells, Cultured; Choline O-Acetyltransfe | 1991 |
[Psychotropics and pregnancy. Apropos of 2 case reports: the dose of triazolam].
Topics: Apnea; Female; Half-Life; Humans; Infant, Newborn; Male; Neonatal Abstinence Syndrome; Pregnancy; Pr | 1989 |