triazolam has been researched along with Drug Withdrawal Symptoms in 70 studies
Triazolam: A short-acting benzodiazepine used in the treatment of insomnia. Some countries temporarily withdrew triazolam from the market because of concerns about adverse reactions, mostly psychological, associated with higher dose ranges. Its use at lower doses with appropriate care and labeling has been reaffirmed by the FDA and most other countries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a parallel-group, placebo-controlled, polysomnographic study with randomization, the possible occurrence of rebound insomnia was evaluated in 24 patients suffering from moderate to severe chronic insomnia and receiving either triazolam 0." | 9.07 | Zolpidem and rebound insomnia--a double-blind, controlled polysomnographic study in chronic insomniac patients. ( Attali, P; de la Giclais, B; Monti, D; Monti, JM; Morselli, PL; Zipfel, A, 1994) |
| "Within a double-blind, comparative study on the effects of the long-half-life benzodiazepine (BDZ), quazepam, and the short-half-life BDZ, triazolam, on clinical symptomatology, sleep and anxiety of 45 patients with insomnia based on a mild to moderate generalized anxiety disorder (GAD) (ICD-9 code: 307." | 9.07 | Insomnia in generalized anxiety disorder: polysomnographic, psychometric and clinical investigations before, during and after therapy with a long- versus a short-half-life benzodiazepine (quazepam versus triazolam). ( Anderer, P; Brandstätter, N; Frey, R; Grünberger, J; Klösch, G; Mandl, M; Saletu, B; Wetter, T; Zeitlhofer, J, 1994) |
| "The authors report a case of a 55-year-old man undergoing a triazolam withdrawal syndrome that was recognized and treated with high doses of benzodiazepines, but the patient nevertheless developed seizures." | 7.67 | Seizures following triazolam withdrawal despite benzodiazepine treatment. ( Pawluczyk, S; Schneider, LS; Syapin, PJ, 1987) |
| "A 53-year-old man with a 3-month addiction to approximately 5 mg/day of triazolam experienced psychosis and delirium following relatively abrupt withdrawal from the drug." | 7.67 | A case of psychosis and delirium following withdrawal from triazolam. ( Capwell, R; Heritch, AJ; Roy-Byrne, PP, 1987) |
| " In conclusion, chronic administration of bupropion (2 and 5 mg/kg) exhibited a significant protection against triazolam withdrawal-induced anxiety and hyperlocomotor activity in mice." | 5.33 | Reversal of triazolam tolerance and withdrawal-induced hyperlocomotor activity and anxiety by bupropion in mice. ( Joshi, D; Kulkarni, SK; Naidu, PS; Singh, A, 2005) |
| "In a parallel-group, placebo-controlled, polysomnographic study with randomization, the possible occurrence of rebound insomnia was evaluated in 24 patients suffering from moderate to severe chronic insomnia and receiving either triazolam 0." | 5.07 | Zolpidem and rebound insomnia--a double-blind, controlled polysomnographic study in chronic insomniac patients. ( Attali, P; de la Giclais, B; Monti, D; Monti, JM; Morselli, PL; Zipfel, A, 1994) |
| "Within a double-blind, comparative study on the effects of the long-half-life benzodiazepine (BDZ), quazepam, and the short-half-life BDZ, triazolam, on clinical symptomatology, sleep and anxiety of 45 patients with insomnia based on a mild to moderate generalized anxiety disorder (GAD) (ICD-9 code: 307." | 5.07 | Insomnia in generalized anxiety disorder: polysomnographic, psychometric and clinical investigations before, during and after therapy with a long- versus a short-half-life benzodiazepine (quazepam versus triazolam). ( Anderer, P; Brandstätter, N; Frey, R; Grünberger, J; Klösch, G; Mandl, M; Saletu, B; Wetter, T; Zeitlhofer, J, 1994) |
| "A double-blind study comparing zopiclone and triazolam, in 48 healthy, chronic insomniacs, was undertaken in two centers to compare the hypnotic and withdrawal effects of both compounds." | 5.06 | A comparison of the efficacy, safety and withdrawal effects of zopiclone and triazolam in the treatment of insomnia. ( Bourgouin, J; Fleming, JA; Mayes, C; McClure, DJ; Phillips, R, 1990) |
| "In this study, we present five cases of seizures following withdrawal of flunitrazepam, lorazepam, or triazolam, representing 3% of a sample consisting of 153 patients dependent on benzodiazepines." | 3.69 | Benzodiazepine withdrawal syndrome seizures. ( de Iceta, M; Martínez-Cano, H; Martínez-Gras, I; Pomalima, R; Vela-Bueno, A, 1995) |
| "The authors report a case of a 55-year-old man undergoing a triazolam withdrawal syndrome that was recognized and treated with high doses of benzodiazepines, but the patient nevertheless developed seizures." | 3.67 | Seizures following triazolam withdrawal despite benzodiazepine treatment. ( Pawluczyk, S; Schneider, LS; Syapin, PJ, 1987) |
| "A 53-year-old man with a 3-month addiction to approximately 5 mg/day of triazolam experienced psychosis and delirium following relatively abrupt withdrawal from the drug." | 3.67 | A case of psychosis and delirium following withdrawal from triazolam. ( Capwell, R; Heritch, AJ; Roy-Byrne, PP, 1987) |
| "Insomnia and anxiety decreased in 12 outpatients taking triazolam following alcohol withdrawal." | 3.65 | Pilot open-label study of triazolam in the treatment of insomnia following alcohol withdrawal. ( Fabre, LF; Gainey, A; Kemple, S; McLendon, DM; Metzler, CM, 1977) |
| "Self-rating scales showed minimal rebound insomnia after discontinuation of all three hypnotics." | 2.70 | A double-blind, randomized and placebo-controlled study on the polysomnographic withdrawal effects of zopiclone, zolpidem and triazolam in healthy subjects. ( Backhaus, J; Berger, M; Feige, B; Hohagen, F; Hornyak, M; Riemann, D; Voderholzer, U, 2001) |
| "This study examined rebound insomnia after discontinuation of chronic use of zolpidem (10 mg), a short elimination half-life imidazopyridine." | 2.68 | Minimal rebound insomnia after treatment with 10-mg zolpidem. ( Roehrs, T; Roth, T; Scharf, MB; Vogel, GW; Walsh, JK; Ware, JC, 1997) |
| "Subjects with rebound insomnia had poorer baseline sleep and a greater drug effect than did subjects without." | 2.67 | Rebound insomnia: duration of use and individual differences. ( Merlotti, L; Roehrs, T; Roth, T; Zorick, F, 1991) |
| "Sixty-five patients, affected by sleep disorders, were entered into the study." | 2.67 | Quazepam versus triazolam in patients with sleep disorders: a double-blind study. ( Altamura, AC; Gianetti, S; Mauri, MC; Pugnetti, L, 1993) |
| "The groups compared were patients with insomnia and disturbed sleep, insomnia and normal sleep, and healthy normals." | 2.67 | Rebound insomnia and hypnotic self administration. ( Merlotti, L; Roehrs, T; Roth, T; Zorick, F, 1992) |
| "Rebound insomnia was studied in subjects, aged 25-50 years, with insomnia complaints and normal sleep, insomnia complaints and disturbed sleep, and normal sleep with no complaints (N = 21, n = 7 per group)." | 2.67 | Rebound insomnia in normals and patients with insomnia after abrupt and tapered discontinuation. ( Merlotti, L; Roehrs, T; Roth, T; Zorick, F, 1992) |
| "With temazepam this effect was more variable, with total wake time increased only with the second withdrawal period (39%)." | 2.67 | Rebound insomnia after only brief and intermittent use of rapidly eliminated benzodiazepines. ( Bixler, EO; Fee, EC; Kales, A; Manfredi, RL; Vela-Bueno, A; Vgontzas, AN, 1991) |
| " In this double-blind study in geriatric patients, drugs were administered during 3 weeks and the therapeutic effects of zopiclone at optimal dosage (5 or 7." | 2.67 | Efficacy and safety of zopiclone and triazolam in the treatment of geriatric insomniacs. ( Bourgouin, J; Elie, R; Frenay, M; Le Morvan, P, 1990) |
| "The study subjects were chronic insomniacs with moderate levels of psychopathology and prior use of hypnotics." | 2.66 | Profile of mood states changes during and after 5 weeks of nightly triazolam administration. ( Bliwise, DL; Bliwise, NG; Cohen, SA; Dement, WC; Seidel, WF, 1988) |
| "Sixty volunteers with insomnia participated in a randomized, double-blind, controlled clinical trial." | 2.66 | Effect of gradual withdrawal on the rebound sleep disorder after discontinuation of triazolam. ( Greenblatt, DJ; Harmatz, JS; Shader, RI; Zinny, MA, 1987) |
| "The risk of rebound insomnia is greater with the short half-life as compared with the long half-life benzodiazepines." | 2.38 | Rebound insomnia: a critical review. ( Gillin, JC; Johnson, LC; Spinweber, CL, 1989) |
| " The signal perceived by the NARD appears to have been a valuable warning, rightly casting doubt on the safety of triazolam and the original dosage recommendations." | 2.38 | [The Halcion affair in 1979, a false alarm?]. ( Meyboom, RH, 1989) |
| "Rebound insomnia has not been noted following withdrawal of flurazepam; there is a carry-over effectiveness into the first and second nights of withdrawal, and any withdrawal sleep disturbance would be expected to be infrequent, delayed in appearance, and mild in degree." | 2.36 | Sleep laboratory studies of hypnotic drugs: efficacy and withdrawal effects. ( Kales, A; Kales, JD, 1983) |
| "Insomnia is defined and described with special attention to differentiating the subjective complaint and the laboratory assessment of objective sleep parameters." | 2.36 | Rational basis for the use of sleeping pills. ( Dement, WC, 1983) |
| " In conclusion, chronic administration of bupropion (2 and 5 mg/kg) exhibited a significant protection against triazolam withdrawal-induced anxiety and hyperlocomotor activity in mice." | 1.33 | Reversal of triazolam tolerance and withdrawal-induced hyperlocomotor activity and anxiety by bupropion in mice. ( Joshi, D; Kulkarni, SK; Naidu, PS; Singh, A, 2005) |
| "The present study investigates the effects of acute and chronic administration of triazolam in albino rats on glycine levels in different brain areas." | 1.31 | Brain glycine levels in triazolam-treated albino rats. ( Aburawi, SM; Ahmed, SS; Attia, AS; Elhwuegi, AS; Saad, SF, 2001) |
| "treatment with alprazolam induced clear physical dependence in DBA/2J mice as assessed by precipitation of a withdrawal syndrome with an i." | 1.28 | Physical dependence induced in DBA/2J mice by benzodiazepine receptor full agonists, but not by the partial agonist Ro 16-6028. ( Haefely, WE; Jenck, F; Martin, JR; Moreau, JL; Pieri, L; Schoch, P, 1990) |
| " We report five cases of high-dose triazolam abuse in which the daily dosage ranged from 5 to 15 mg (100-300 mg diazepam equivalent) and the duration of use ranged from 3 months to 5 years." | 1.28 | Detoxification for triazolam physical dependence. ( Sellers, EM; Sullivan, JT, 1992) |
| "for 14 days) exhibited a higher seizure susceptibility than their corresponding controls." | 1.27 | Subacute benzodiazepine treatment: observations on behavioural tolerance and withdrawal. ( Gonzalez, JP; McCulloch, AJ; Nicholls, PJ; Sewell, RD; Tekle, A, 1984) |
| "We report two cases of severe withdrawal symptoms after abrupt discontinuation of a long-term normal-dose benzodiazepines (BZD) administration." | 1.27 | [Two cases of psychotic state following normal-dose benzodiazepine withdrawal]. ( Tani, Y; Terao, T, 1988) |
| " During chronic administration of brotizolam, triazolam and diazepam all animals gained body weight." | 1.27 | Physical dependence capacity of brotizolam in rhesus monkeys. 2nd communication: primary dependence and barbital substitution. ( Stockhaus, K, 1986) |
| " In naive animals, after the chronic administration of midazolam at 0." | 1.27 | [Drug dependence tests on a new anesthesia inducer, midazolam]. ( Hakkei, M; Kubota, A; Kuwahara, A; Nakamura, K, 1986) |
| "Rebound insomnia followed the withdrawal of three benzodiazepine hypnotic drugs, each of which had been administered in a single nightly dose for only short-term periods." | 1.26 | Rebound insomnia: a new clinical syndrome. ( Kales, A; Kales, JD; Scharf, MB, 1978) |
| "Rebound insomnia, a worsening of sleep compared with baseline, occurred following withdrawal of triazolam, nitrazepam, and flunitrazepam after they had been given in only single, nightly doses for short periods." | 1.26 | Rebound insomnia. A potential hazard following withdrawal of certain benzodiazepines. ( Kales, A; Kales, JD; Scharf, MB; Soldatos, CR, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (54.29) | 18.7374 |
| 1990's | 27 (38.57) | 18.2507 |
| 2000's | 5 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Joshi, D | 1 |
| Naidu, PS | 1 |
| Singh, A | 1 |
| Kulkarni, SK | 1 |
| Weerts, EM | 2 |
| Ator, NA | 6 |
| Kaminski, BJ | 1 |
| Griffiths, RR | 8 |
| Matsuda, N | 1 |
| Nakamura, K | 2 |
| Watanabe, A | 1 |
| Endo, K | 1 |
| Yamamoto, T | 1 |
| Morgan, K | 1 |
| Oswald, I | 3 |
| Kales, A | 8 |
| Kales, JD | 6 |
| Mitler, MM | 1 |
| Seidel, WF | 2 |
| van den Hoed, J | 1 |
| Greenblatt, DJ | 2 |
| Dement, WC | 3 |
| Adam, K | 2 |
| Shapiro, C | 1 |
| Bechelli, LP | 1 |
| Navas, F | 1 |
| Pierangelo, SA | 1 |
| Lukas, SE | 1 |
| Lamb, RJ | 3 |
| Brady, JV | 4 |
| Feldbaum, JS | 1 |
| Gonzalez, JP | 1 |
| McCulloch, AJ | 1 |
| Nicholls, PJ | 1 |
| Sewell, RD | 1 |
| Tekle, A | 1 |
| Bixler, EO | 4 |
| Cumin, R | 1 |
| Bonetti, EP | 1 |
| Scherschlicht, R | 1 |
| Haefely, WE | 2 |
| Nicholson, AN | 1 |
| Ladewig, D | 1 |
| Woods, JH | 1 |
| Winger, G | 1 |
| Nazareth, I | 1 |
| Ashworth, M | 1 |
| Hammond, J | 1 |
| King, M | 1 |
| Mauri, MC | 1 |
| Gianetti, S | 1 |
| Pugnetti, L | 1 |
| Altamura, AC | 1 |
| Monti, JM | 1 |
| Attali, P | 1 |
| Monti, D | 1 |
| Zipfel, A | 1 |
| de la Giclais, B | 1 |
| Morselli, PL | 1 |
| O'Donovan, MC | 1 |
| McGuffin, P | 1 |
| Saletu, B | 1 |
| Anderer, P | 1 |
| Brandstätter, N | 1 |
| Frey, R | 1 |
| Grünberger, J | 1 |
| Klösch, G | 1 |
| Mandl, M | 1 |
| Wetter, T | 1 |
| Zeitlhofer, J | 1 |
| Martínez-Cano, H | 1 |
| Vela-Bueno, A | 2 |
| de Iceta, M | 1 |
| Pomalima, R | 1 |
| Martínez-Gras, I | 1 |
| Ramsey-Williams, VA | 1 |
| Carter, DB | 1 |
| Ware, JC | 1 |
| Walsh, JK | 1 |
| Scharf, MB | 3 |
| Roehrs, T | 4 |
| Roth, T | 4 |
| Vogel, GW | 1 |
| Feige, B | 2 |
| Voderholzer, U | 2 |
| Riemann, D | 2 |
| Hohagen, F | 2 |
| Berger, M | 2 |
| Aburawi, SM | 1 |
| Ahmed, SS | 1 |
| Elhwuegi, AS | 1 |
| Saad, SF | 1 |
| Attia, AS | 1 |
| Hornyak, M | 1 |
| Backhaus, J | 1 |
| Fabre, LF | 1 |
| Gainey, A | 1 |
| Kemple, S | 1 |
| McLendon, DM | 1 |
| Metzler, CM | 1 |
| Soldatos, CR | 2 |
| Sannerud, CA | 1 |
| Sullivan, JT | 1 |
| Sellers, EM | 1 |
| Merlotti, L | 3 |
| Zorick, F | 3 |
| Rothschild, AJ | 1 |
| Moreau, JL | 1 |
| Jenck, F | 1 |
| Pieri, L | 1 |
| Schoch, P | 1 |
| Martin, JR | 1 |
| Manfredi, RL | 1 |
| Vgontzas, AN | 1 |
| Fee, EC | 1 |
| Schneider, PJ | 1 |
| Perry, PJ | 1 |
| Fleming, JA | 2 |
| McClure, DJ | 1 |
| Mayes, C | 1 |
| Phillips, R | 1 |
| Bourgouin, J | 2 |
| Elie, R | 1 |
| Frenay, M | 1 |
| Le Morvan, P | 1 |
| Mouret, J | 1 |
| Ruel, D | 1 |
| Maillard, F | 1 |
| Bianchi, M | 1 |
| Gillin, JC | 1 |
| Spinweber, CL | 1 |
| Johnson, LC | 1 |
| Rapport, DJ | 1 |
| Covington, EC | 1 |
| Meyboom, RH | 1 |
| Roache, JD | 2 |
| Jacoby, JA | 1 |
| Lynn, EJ | 1 |
| Schneider, LS | 1 |
| Syapin, PJ | 1 |
| Pawluczyk, S | 1 |
| Albeck, JH | 1 |
| Brubaker, BH | 1 |
| Terao, T | 1 |
| Tani, Y | 1 |
| Bliwise, DL | 1 |
| Cohen, SA | 1 |
| Bliwise, NG | 1 |
| Lamb, R | 1 |
| Bigelow, GE | 1 |
| Harmatz, JS | 1 |
| Zinny, MA | 1 |
| Shader, RI | 1 |
| Patterson, WM | 1 |
| Heritch, AJ | 1 |
| Capwell, R | 1 |
| Roy-Byrne, PP | 1 |
| Rungta, K | 1 |
| Isomura, T | 1 |
| McMillan, MJ | 1 |
| Stockhaus, K | 1 |
| Kubota, A | 1 |
| Kuwahara, A | 1 |
| Hakkei, M | 1 |
| Singh, AN | 1 |
| Chemij, M | 1 |
| Jewell, J | 1 |
| Tien, AY | 1 |
| Gujavarty, KS | 1 |
11 reviews available for triazolam and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Sleep laboratory studies of hypnotic drugs: efficacy and withdrawal effects.
Topics: Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Dose-Response Relationship, Drug; Fl | 1983 |
Rational basis for the use of sleeping pills.
Topics: Anxiety; Chronic Disease; Flurazepam; Humans; Hypnotics and Sedatives; Kinetics; Sleep; Sleep Initia | 1983 |
Current benzodiazepine issues.
Topics: Age Factors; Benzodiazepines; Humans; Memory Disorders; Risk Factors; Substance Withdrawal Syndrome; | 1995 |
Disinhibition, amnestic reactions, and other adverse reactions secondary to triazolam: a review of the literature.
Topics: Amnesia; Benzodiazepines; Delirium; Double-Blind Method; Humans; Placebos; Randomized Controlled Tri | 1992 |
Benzodiazepine hypnotics and insomnia.
Topics: Anti-Anxiety Agents; Humans; Hypnotics and Sedatives; Psychotherapy; Sleep Initiation and Maintenanc | 1990 |
Triazolam--an "abused drug" by the lay press?
Topics: Amnesia; Communication; Humans; Mass Media; Psychoses, Substance-Induced; Substance Withdrawal Syndr | 1990 |
Rebound insomnia: a critical review.
Topics: Anti-Anxiety Agents; Flurazepam; Humans; Sleep Initiation and Maintenance Disorders; Sleep Stages; S | 1989 |
[The Halcion affair in 1979, a false alarm?].
Topics: Drug and Narcotic Control; Humans; Mental Disorders; Netherlands; Substance Withdrawal Syndrome; Syn | 1989 |
Relative abuse liability of triazolam: experimental assessment in animals and humans.
Topics: Amnesia; Animals; Anti-Anxiety Agents; Behavior, Animal; Discrimination, Psychological; Drug Interac | 1985 |
Rebound insomnia and elimination half-life: assessment of individual subject response.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Dose-Response Relationship, D | 1985 |
Withdrawal and detoxification from benzodiazepine dependence: a potential role for clonazepam.
Topics: Adolescent; Adult; Aged; Alprazolam; Anti-Anxiety Agents; Clonazepam; Diazepam; Drug Tolerance; Huma | 1987 |
18 trials available for triazolam and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Anxiety caused by a short-life hypnotic.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones; Clinical Trials as Topic | 1982 |
Comparative hypnotic effects of flurazepam, triazolam, and placebo: a long-term simultaneous nighttime and daytime study.
Topics: Adult; Anti-Anxiety Agents; Female; Flurazepam; Humans; Male; Middle Aged; Sleep; Sleep Stages; Subs | 1984 |
Quazepam versus triazolam in patients with sleep disorders: a double-blind study.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Double-Blind Method; Female; Human | 1993 |
Zolpidem and rebound insomnia--a double-blind, controlled polysomnographic study in chronic insomniac patients.
Topics: Adult; Aged; Anxiety; Chronic Disease; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; | 1994 |
Insomnia in generalized anxiety disorder: polysomnographic, psychometric and clinical investigations before, during and after therapy with a long- versus a short-half-life benzodiazepine (quazepam versus triazolam).
Topics: Adult; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Double-Blind Method; Female; Humans; Hypnotics | 1994 |
Minimal rebound insomnia after treatment with 10-mg zolpidem.
Topics: Adult; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Polysomnogra | 1997 |
Independent sleep EEG slow-wave and spindle band dynamics associated with 4 weeks of continuous application of short-half-life hypnotics in healthy subjects.
Topics: Adult; Azabicyclo Compounds; Double-Blind Method; Electroencephalography; Humans; Hypnotics and Seda | 1999 |
A double-blind, randomized and placebo-controlled study on the polysomnographic withdrawal effects of zopiclone, zolpidem and triazolam in healthy subjects.
Topics: Adult; Azabicyclo Compounds; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalo | 2001 |
Rebound insomnia in normals and patients with insomnia after abrupt and tapered discontinuation.
Topics: Adult; Double-Blind Method; Female; Humans; Male; Middle Aged; Sleep Initiation and Maintenance Diso | 1992 |
Rebound insomnia and hypnotic self administration.
Topics: Adult; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Self Adminis | 1992 |
Rebound insomnia: duration of use and individual differences.
Topics: Adult; Drug Tolerance; Electroencephalography; Humans; Male; Monitoring, Physiologic; Sleep Initiati | 1991 |
Rebound insomnia after only brief and intermittent use of rapidly eliminated benzodiazepines.
Topics: Adult; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Random Allocation; Sleep Initiati | 1991 |
A comparison of the efficacy, safety and withdrawal effects of zopiclone and triazolam in the treatment of insomnia.
Topics: Adolescent; Adult; Azabicyclo Compounds; Double-Blind Method; Female; Humans; Hypnotics and Sedative | 1990 |
Efficacy and safety of zopiclone and triazolam in the treatment of geriatric insomniacs.
Topics: Aged; Aged, 80 and over; Arousal; Azabicyclo Compounds; Dose-Response Relationship, Drug; Double-Bli | 1990 |
Zopiclone versus triazolam in insomniac geriatric patients: a specific increase in delta sleep with zopiclone.
Topics: Aged; Aged, 80 and over; Arousal; Azabicyclo Compounds; Delta Rhythm; Double-Blind Method; Electroen | 1990 |
Rebound insomnia and elimination half-life: assessment of individual subject response.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Dose-Response Relationship, D | 1985 |
Profile of mood states changes during and after 5 weeks of nightly triazolam administration.
Topics: Adult; Anxiety Disorders; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; MMPI; | 1988 |
Effect of gradual withdrawal on the rebound sleep disorder after discontinuation of triazolam.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Female; Humans; | 1987 |
42 other studies available for triazolam and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Reversal of triazolam tolerance and withdrawal-induced hyperlocomotor activity and anxiety by bupropion in mice.
Topics: Animals; Anxiety; Bupropion; Dopamine; Drug Tolerance; Female; Male; Mice; Motor Activity; Norepinep | 2005 |
Comparison of the behavioral effects of bretazenil and flumazenil in triazolam-dependent and non-dependent baboons.
Topics: Animals; Behavior, Animal; Benzodiazepinones; Dose-Response Relationship, Drug; Eating; Flumazenil; | 2005 |
[Non-convulsive status epilepticus due to discontinuation of taking a benzodiazepine].
Topics: Aged; Electroencephalography; Female; Humans; Hypnotics and Sedatives; Status Epilepticus; Substance | 2006 |
Effects of loprazolam and of triazolam on sleep and overnight urinary cortisol.
Topics: Aged; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Catecholamines; Drug Tolerance; Femal | 1984 |
Comparison of the reinforcing properties of zopiclone and triazolam in former alcoholics.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Azabicyclo Compounds; Capsules; Double-Blind Method; Electro | 1982 |
Benzodiazepines: drug discrimination and physiological dependence.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Bromazepam; Diazepam; Discrimination Lear | 1984 |
Inadvertent benzodiazepine withdrawal.
Topics: Anti-Anxiety Agents; Flurazepam; Humans; Male; Middle Aged; Sleep Initiation and Maintenance Disorde | 1984 |
Subacute benzodiazepine treatment: observations on behavioural tolerance and withdrawal.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Conditioning, Psychological; Diazepam; Drinking Beha | 1984 |
Commentary--avoiding problems in the sleep laboratory.
Topics: Drug Evaluation; Humans; Hypnotics and Sedatives; Research Design; Sleep; Substance Withdrawal Syndr | 1984 |
Use of the specific benzodiazepine antagonist, Ro 15-1788, in studies of physiological dependence on benzodiazepines.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Cats; Diazepam; Female; Flumazenil; Humans; Lorazepam; | 1982 |
Hypnotics: rebound insomnia and residual sequelae.
Topics: Humans; Hypnotics and Sedatives; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Sy | 1980 |
Systematic review of the benzodiazepines. Guidelines for data sheets on diazepam, chlordiazepoxide, medazepam, clorazepate, lorazepam, oxazepam, temazepam, triazolam, nitrazepam, and flurazepam. Committee on the Review of Medicines.
Topics: Benzodiazepines; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Flurazepam; Humans; Lorazepam; | 1980 |
[Does a rebound insomnia following benzodiazepine administration exist?].
Topics: Benzodiazepines; Diazepam; Flunitrazepam; Flurazepam; Humans; Nitrazepam; Sleep Initiation and Maint | 1980 |
Withdrawal of triazolam's product licence: effect on patients 18 months later.
Topics: Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Drug Approval; Drug Utilization; Female; Follow | 1995 |
Short acting benzodiazepines.
Topics: Amnesia; Anti-Anxiety Agents; Anxiety; Depression; Half-Life; Humans; Sleep Initiation and Maintenan | 1993 |
Benzodiazepine withdrawal syndrome seizures.
Topics: Adult; Anti-Anxiety Agents; Female; Flunitrazepam; Heroin Dependence; Humans; Hypnotics and Sedative | 1995 |
Chronic triazolam and its withdrawal alters GABAA receptor subunit mRNA levels: an in situ hybridization study.
Topics: Animals; Brain; Female; In Situ Hybridization; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, M | 1996 |
Evaluation of limited and unlimited food intake during withdrawal in triazolam-dependent baboons.
Topics: Animals; Conditioning, Operant; Eating; Hypnotics and Sedatives; Male; Papio; Reinforcement Schedule | 1999 |
Brain glycine levels in triazolam-treated albino rats.
Topics: Animals; Anti-Anxiety Agents; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Drug Adminis | 2001 |
Pilot open-label study of triazolam in the treatment of insomnia following alcohol withdrawal.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Anxiety; Drug Evaluation; Female; Humans; Male; Middle Aged; | 1977 |
Rebound insomnia. A potential hazard following withdrawal of certain benzodiazepines.
Topics: Acute Disease; Benzodiazepines; Flunitrazepam; Half-Life; Humans; Nitrazepam; Sleep Initiation and M | 1979 |
Rebound insomnia: a new clinical syndrome.
Topics: Benzodiazepines; Brain; Flunitrazepam; Humans; Hypnotics and Sedatives; Nitrazepam; Receptors, Drug; | 1978 |
Zolpidem behavioral pharmacology in baboons: self-injection, discrimination, tolerance and withdrawal.
Topics: Animals; Barbiturates; Cocaine; Discrimination Learning; Drug Tolerance; Hypnotics and Sedatives; Ma | 1992 |
Detoxification for triazolam physical dependence.
Topics: Adult; Alcoholism; Diazepam; Dose-Response Relationship, Drug; Female; Half-Life; Hospitalization; H | 1992 |
Oral self-administration of triazolam, diazepam and ethanol in the baboon: drug reinforcement and benzodiazepine physical dependence.
Topics: Animals; Conditioning, Operant; Diazepam; Drinking Behavior; Ethanol; Flumazenil; Food; Half-Life; M | 1992 |
Possible mechanism for adverse reactions to triazolam.
Topics: Alprazolam; Anxiety; Humans; Platelet Activating Factor; Receptors, GABA-A; Substance Withdrawal Syn | 1991 |
Triazolam in the elderly.
Topics: Adult; Aged; Aged, 80 and over; Humans; Male; Memory Disorders; Substance Withdrawal Syndrome; Triaz | 1991 |
Physical dependence induced in DBA/2J mice by benzodiazepine receptor full agonists, but not by the partial agonist Ro 16-6028.
Topics: Administration, Oral; Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepinones; Diazepam; Drug Im | 1990 |
Motor phenomena in benzodiazepine withdrawal.
Topics: Aged; Alprazolam; Anti-Anxiety Agents; Diagnosis, Differential; Diazepam; Drug Therapy, Combination; | 1989 |
Effects of repeated RO 15-1788 administration in benzodiazepine-dependent baboons.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Convulsants; Diazepam; Drug Tolerance; Flumazenil; | 1985 |
Triazolam addiction.
Topics: Adult; Anti-Anxiety Agents; Diazepam; Humans; Male; Substance Withdrawal Syndrome; Substance-Related | 1985 |
Seizures following triazolam withdrawal despite benzodiazepine treatment.
Topics: Anti-Anxiety Agents; Anxiety Disorders; Chlordiazepoxide; Diazepam; Humans; Male; Middle Aged; Recep | 1987 |
Adverse reactions to benzodiazepine hypnotics: spontaneous reporting system.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Anxiety Agents; Female; Flurazepam; Humans; Hypnot | 1987 |
[Two cases of psychotic state following normal-dose benzodiazepine withdrawal].
Topics: Anti-Anxiety Agents; Cognition Disorders; Female; Humans; Male; Middle Aged; Nitrazepam; Perceptual | 1988 |
Progress report from the Division of Behavioral Biology, the Johns Hopkins University School of Medicine.
Topics: Animals; Drug Tolerance; Humans; Male; Maryland; Papio; Pentobarbital; Research; Self Administration | 1986 |
Triazolam withdrawal.
Topics: Alprazolam; Diazepam; Drug Tolerance; Humans; Seizures; Substance Withdrawal Syndrome; Triazolam | 1988 |
A case of psychosis and delirium following withdrawal from triazolam.
Topics: Delirium; Humans; Lorazepam; Male; Middle Aged; Psychoses, Substance-Induced; Substance Withdrawal S | 1987 |
Withdrawal regimen for triazolam-dependent patients.
Topics: Diazepam; Flurazepam; Humans; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndr | 1986 |
Physical dependence capacity of brotizolam in rhesus monkeys. 2nd communication: primary dependence and barbital substitution.
Topics: Animals; Azepines; Barbital; Barbiturates; Body Weight; Diazepam; Female; Hypnotics and Sedatives; M | 1986 |
[Drug dependence tests on a new anesthesia inducer, midazolam].
Topics: Animals; Injections, Intravenous; Macaca fascicularis; Male; Midazolam; Pentobarbital; Self Administ | 1986 |
Treatment of triazolam dependence with a tapering withdrawal regimen.
Topics: Adult; Humans; Male; Placebos; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Fact | 1986 |
Seizure following withdrawal from triazolam.
Topics: Adult; Female; Humans; Seizures; Substance Withdrawal Syndrome; Triazolam | 1985 |