Page last updated: 2024-11-05

triazolam and Ataxia

triazolam has been researched along with Ataxia in 5 studies

Triazolam: A short-acting benzodiazepine used in the treatment of insomnia. Some countries temporarily withdrew triazolam from the market because of concerns about adverse reactions, mostly psychological, associated with higher dose ranges. Its use at lower doses with appropriate care and labeling has been reaffirmed by the FDA and most other countries.

Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.

Research Excerpts

ExcerptRelevanceReference
"Sleepiness, agitation and ataxia were significantly more frequent in the children."5.28Acute poisonings with ethyle loflazepate, flunitrazepam, prazepam and triazolam in children. ( Descotes, J; Frantz, P; Mollon, P; Pham, E; Pulce, C, 1992)
"Zolpidem and triazolam produced dose-dependent reductions in locomotion and environment-directed behavior and increased ataxia and procumbent posture."3.71Selective antagonism of the ataxic effects of zolpidem and triazolam by the GABAA/alpha1-preferring antagonist beta-CCt in squirrel monkeys. ( Cook, J; Ma, C; Platt, DM; Rowlett, JK; Spealman, RD, 2002)
" The peak concentration was 4."2.70Pharmacokinetics and clinical effects of sublingual triazolam in pediatric dental patients. ( Coldwell, SE; Kaakko, T; Kharasch, ED; Milgrom, P; Spieker, M; Tweedy, CM, 2001)
"Triazolam has shown promise as a sedative agent for use in pediatric dentistry."2.69A randomized clinical trial of triazolam in 3- to 5-year-olds. ( Coldwell, SE; Kaakko, T; Karl, HW; Milgrom, P; Perkis, V; Raadal, M; Weinstein, P, 1999)
"Sleepiness, agitation and ataxia were significantly more frequent in the children."1.28Acute poisonings with ethyle loflazepate, flunitrazepam, prazepam and triazolam in children. ( Descotes, J; Frantz, P; Mollon, P; Pham, E; Pulce, C, 1992)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Platt, DM1
Rowlett, JK1
Spealman, RD1
Cook, J1
Ma, C1
Raadal, M1
Coldwell, SE2
Kaakko, T2
Milgrom, P2
Weinstein, P1
Perkis, V1
Karl, HW1
Tweedy, CM1
Kharasch, ED1
Spieker, M1
Wang, RI1
Wilbur, M1
Hieb, E1
Pulce, C1
Mollon, P1
Pham, E1
Frantz, P1
Descotes, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Oral Anxiolysis for the Older Pediatric Patient-Which Medication is Preferred?[NCT03360123]4 participants (Actual)Interventional2018-01-26Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for triazolam and Ataxia

ArticleYear
A randomized clinical trial of triazolam in 3- to 5-year-olds.
    Journal of dental research, 1999, Volume: 78, Issue:6

    Topics: Administration, Oral; Anesthesia, Dental; Ataxia; Behavior Therapy; Chi-Square Distribution; Child B

1999
Pharmacokinetics and clinical effects of sublingual triazolam in pediatric dental patients.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:3

    Topics: Administration, Sublingual; Amnesia; Anti-Anxiety Agents; Area Under Curve; Ataxia; Child; Child, Pr

2001
Determining optimum dose and acute tolerance of triazolam.
    The Journal of international medical research, 1977, Volume: 5, Issue:3

    Topics: Adult; Anti-Anxiety Agents; Ataxia; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug

1977

Other Studies

2 other studies available for triazolam and Ataxia

ArticleYear
Selective antagonism of the ataxic effects of zolpidem and triazolam by the GABAA/alpha1-preferring antagonist beta-CCt in squirrel monkeys.
    Psychopharmacology, 2002, Volume: 164, Issue:2

    Topics: Animals; Ataxia; Benzodiazepines; Carbolines; Dose-Response Relationship, Drug; Drug Interactions; F

2002
Acute poisonings with ethyle loflazepate, flunitrazepam, prazepam and triazolam in children.
    Veterinary and human toxicology, 1992, Volume: 34, Issue:2

    Topics: Adolescent; Age Factors; Anti-Anxiety Agents; Ataxia; Benzodiazepines; Benzodiazepinones; Child, Pre

1992