triazolam has been researched along with Anxiety in 40 studies
Triazolam: A short-acting benzodiazepine used in the treatment of insomnia. Some countries temporarily withdrew triazolam from the market because of concerns about adverse reactions, mostly psychological, associated with higher dose ranges. Its use at lower doses with appropriate care and labeling has been reaffirmed by the FDA and most other countries.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We prospectively evaluated the effect on amnesia of triazolam administered during the preoperative period in 80 patients between 20-64 years of age (mean, 43." | 9.15 | [Comprehensive evaluation of the effect of triazolam on amnesia during the preoperative period]. ( Iida, R; Kajiwara, K; Kashiwai, A; Kato, J; Ogawa, S, 2011) |
| " Our data indicate that oral triazolam is beneficial in decreasing pain and anxiety associated with self-activated atrial defibrillation." | 9.12 | Decreasing pain and anxiety associated with patient-activated atrial shock: a placebo-controlled study of adjunctive sedation with oral triazolam. ( Bigos, KL; Corey, SE; Fabian, TJ; Kroboth, PD; Pollock, BG; Schwartzman, DS; Ujhelyi, MR, 2006) |
| "In a parallel-group, placebo-controlled, polysomnographic study with randomization, the possible occurrence of rebound insomnia was evaluated in 24 patients suffering from moderate to severe chronic insomnia and receiving either triazolam 0." | 9.07 | Zolpidem and rebound insomnia--a double-blind, controlled polysomnographic study in chronic insomniac patients. ( Attali, P; de la Giclais, B; Monti, D; Monti, JM; Morselli, PL; Zipfel, A, 1994) |
| "Within a double-blind, comparative study on the effects of the long-half-life benzodiazepine (BDZ), quazepam, and the short-half-life BDZ, triazolam, on clinical symptomatology, sleep and anxiety of 45 patients with insomnia based on a mild to moderate generalized anxiety disorder (GAD) (ICD-9 code: 307." | 9.07 | Insomnia in generalized anxiety disorder: polysomnographic, psychometric and clinical investigations before, during and after therapy with a long- versus a short-half-life benzodiazepine (quazepam versus triazolam). ( Anderer, P; Brandstätter, N; Frey, R; Grünberger, J; Klösch, G; Mandl, M; Saletu, B; Wetter, T; Zeitlhofer, J, 1994) |
| "The purpose of this investigation was to determine if the preoperative administration of an oral anxiolytic agent (triazolam) is beneficial in reducing the cardiovascular response to stress and anxiety." | 9.07 | Attenuation of anxiety in ambulatory oral surgery patients with oral triazolam. ( Horswell, B; Lieblich, SE, 1991) |
| " The dosage was doubled after nights 2 and 9 if good sleep was not produced." | 6.64 | Multi-clinic cross-over comparison of triazolam (Halcion) and placebo in the treatment of co-existing insomnia and anxiety in anxious out-patients. ( Fabre, LF; Smith, WT, 1977) |
| " In conclusion, chronic administration of bupropion (2 and 5 mg/kg) exhibited a significant protection against triazolam withdrawal-induced anxiety and hyperlocomotor activity in mice." | 5.33 | Reversal of triazolam tolerance and withdrawal-induced hyperlocomotor activity and anxiety by bupropion in mice. ( Joshi, D; Kulkarni, SK; Naidu, PS; Singh, A, 2005) |
| "We prospectively evaluated the effect on amnesia of triazolam administered during the preoperative period in 80 patients between 20-64 years of age (mean, 43." | 5.15 | [Comprehensive evaluation of the effect of triazolam on amnesia during the preoperative period]. ( Iida, R; Kajiwara, K; Kashiwai, A; Kato, J; Ogawa, S, 2011) |
| " Our data indicate that oral triazolam is beneficial in decreasing pain and anxiety associated with self-activated atrial defibrillation." | 5.12 | Decreasing pain and anxiety associated with patient-activated atrial shock: a placebo-controlled study of adjunctive sedation with oral triazolam. ( Bigos, KL; Corey, SE; Fabian, TJ; Kroboth, PD; Pollock, BG; Schwartzman, DS; Ujhelyi, MR, 2006) |
| "In a parallel-group, placebo-controlled, polysomnographic study with randomization, the possible occurrence of rebound insomnia was evaluated in 24 patients suffering from moderate to severe chronic insomnia and receiving either triazolam 0." | 5.07 | Zolpidem and rebound insomnia--a double-blind, controlled polysomnographic study in chronic insomniac patients. ( Attali, P; de la Giclais, B; Monti, D; Monti, JM; Morselli, PL; Zipfel, A, 1994) |
| "Within a double-blind, comparative study on the effects of the long-half-life benzodiazepine (BDZ), quazepam, and the short-half-life BDZ, triazolam, on clinical symptomatology, sleep and anxiety of 45 patients with insomnia based on a mild to moderate generalized anxiety disorder (GAD) (ICD-9 code: 307." | 5.07 | Insomnia in generalized anxiety disorder: polysomnographic, psychometric and clinical investigations before, during and after therapy with a long- versus a short-half-life benzodiazepine (quazepam versus triazolam). ( Anderer, P; Brandstätter, N; Frey, R; Grünberger, J; Klösch, G; Mandl, M; Saletu, B; Wetter, T; Zeitlhofer, J, 1994) |
| "5 mg), diazepam (5, 10, or 15 mg), or placebo to evaluate the effectiveness of these drugs and doses in reducing preoperative anxiety, providing sedation, and producing amnesia." | 5.06 | Effectiveness of triazolam, diazepam, and placebo as preanesthetic medications. ( Abenstein, JP; Baughman, VL; Becker, GL; Glaser, M; Ryan, CM, 1989) |
| "Insomnia and anxiety decreased in 12 outpatients taking triazolam following alcohol withdrawal." | 3.65 | Pilot open-label study of triazolam in the treatment of insomnia following alcohol withdrawal. ( Fabre, LF; Gainey, A; Kemple, S; McLendon, DM; Metzler, CM, 1977) |
| "Triazolam was shown to be a reinforcer in four of the six subjects." | 2.68 | Reinforcing effects of triazolam in sedative abusers: correlation of drug liking and self-administration measures. ( Henningfield, JE; Jaffe, JH; Klein, S; Meisch, RA; Roache, JD; Sampson, A, 1995) |
| "Sixty-five patients, affected by sleep disorders, were entered into the study." | 2.67 | Quazepam versus triazolam in patients with sleep disorders: a double-blind study. ( Altamura, AC; Gianetti, S; Mauri, MC; Pugnetti, L, 1993) |
| "Triazolam was found to have an antidepressant effect (alpha less than 0." | 2.67 | [Premedication with triazolam]. ( Glaser, KH; Höfler, H; Smonig, H, 1990) |
| "Triazolam was shown to have a pronounced amnesic effect and whilst it might be used for premedication, its lack of anxiolysis coupled with a significant impairment of psychomotor performance at 3 hours after awakening, render the drug unsuitable for premedication in the short stay patient." | 2.66 | A comparison of triazolam and diazepam as premedication agents for minor gynaecological surgery. ( Fell, D; Hunt, PC; Miller, R; Pinnock, CA; Smith, G, 1985) |
| "Triazolam and lorazepam were each associated with a significant reduction in anxiety compared to the initial assessment, whereas placebo had no anxiolytic effect." | 2.66 | Triazolam premedication. A comparison with lorazepam and placebo in gynaecological patients. ( Blogg, CE; Halifax, R; Hollands, MA; Thomas, D; Tipping, T, 1986) |
| " The dosage was doubled after nights 2 and 9 if good sleep was not produced." | 2.64 | Multi-clinic cross-over comparison of triazolam (Halcion) and placebo in the treatment of co-existing insomnia and anxiety in anxious out-patients. ( Fabre, LF; Smith, WT, 1977) |
| "Flurazepam is a long elimination half-life drug, and there is significant daytime sedation during short term use; with continued use this effect diminishes." | 2.36 | Sleep laboratory studies of hypnotic drugs: efficacy and withdrawal effects. ( Kales, A; Kales, JD, 1983) |
| "The diagnosis and treatment of insomnia is a major clinical issue." | 2.36 | Rational basis for the use of sleeping pills. ( Dement, WC, 1983) |
| "Diazepam was used as a positive control." | 1.35 | Evaluation of anxiolytic-like effects of some short-acting benzodiazepine hypnotics in mice. ( Kamei, C; Nishino, T; Takechi, K; Takeuchi, T, 2008) |
| " In conclusion, chronic administration of bupropion (2 and 5 mg/kg) exhibited a significant protection against triazolam withdrawal-induced anxiety and hyperlocomotor activity in mice." | 1.33 | Reversal of triazolam tolerance and withdrawal-induced hyperlocomotor activity and anxiety by bupropion in mice. ( Joshi, D; Kulkarni, SK; Naidu, PS; Singh, A, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (47.50) | 18.7374 |
| 1990's | 11 (27.50) | 18.2507 |
| 2000's | 5 (12.50) | 29.6817 |
| 2010's | 5 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shadli, SM | 1 |
| Smith, MJ | 1 |
| Glue, P | 2 |
| McNaughton, N | 2 |
| Gunter, BW | 1 |
| Jones, SA | 1 |
| Paul, IA | 1 |
| Platt, DM | 1 |
| Rowlett, JK | 2 |
| Nishino, T | 1 |
| Takeuchi, T | 1 |
| Takechi, K | 1 |
| Kamei, C | 1 |
| Iida, R | 1 |
| Kajiwara, K | 1 |
| Kashiwai, A | 1 |
| Kato, J | 1 |
| Ogawa, S | 1 |
| Fischer, BD | 1 |
| Swart, C | 1 |
| Neo, P | 1 |
| Bates, V | 1 |
| Joshi, D | 1 |
| Naidu, PS | 1 |
| Singh, A | 1 |
| Kulkarni, SK | 1 |
| Ganzberg, SI | 1 |
| Dietrich, T | 1 |
| Valerin, M | 1 |
| Beck, FM | 1 |
| Fabian, TJ | 1 |
| Schwartzman, DS | 1 |
| Ujhelyi, MR | 1 |
| Corey, SE | 1 |
| Bigos, KL | 1 |
| Pollock, BG | 1 |
| Kroboth, PD | 1 |
| Vansickel, AR | 1 |
| Hays, LR | 1 |
| Rush, CR | 1 |
| Oswald, I | 5 |
| Kales, A | 3 |
| Kales, JD | 1 |
| Dement, WC | 1 |
| Roache, JD | 1 |
| Meisch, RA | 1 |
| Henningfield, JE | 1 |
| Jaffe, JH | 1 |
| Klein, S | 1 |
| Sampson, A | 1 |
| Mauri, MC | 1 |
| Gianetti, S | 1 |
| Pugnetti, L | 1 |
| Altamura, AC | 1 |
| Monti, JM | 1 |
| Attali, P | 1 |
| Monti, D | 1 |
| Zipfel, A | 1 |
| de la Giclais, B | 1 |
| Morselli, PL | 1 |
| O'Donovan, MC | 1 |
| McGuffin, P | 1 |
| Saletu, B | 1 |
| Anderer, P | 1 |
| Brandstätter, N | 1 |
| Frey, R | 1 |
| Grünberger, J | 1 |
| Klösch, G | 1 |
| Mandl, M | 1 |
| Wetter, T | 1 |
| Zeitlhofer, J | 1 |
| Martínez-Cano, H | 1 |
| Vela-Bueno, A | 2 |
| Kontinen, VK | 1 |
| Maunuksela, EL | 1 |
| Sarvela, J | 1 |
| Fabre, LF | 2 |
| Smith, WT | 1 |
| Gainey, A | 1 |
| Kemple, S | 1 |
| McLendon, DM | 1 |
| Metzler, CM | 1 |
| Adam, K | 2 |
| Lieblich, SE | 1 |
| Horswell, B | 1 |
| Smonig, H | 1 |
| Glaser, KH | 1 |
| Höfler, H | 1 |
| Fogerty, C | 1 |
| Young, ER | 1 |
| Mason, DR | 1 |
| Baughman, VL | 1 |
| Becker, GL | 1 |
| Ryan, CM | 1 |
| Glaser, M | 1 |
| Abenstein, JP | 1 |
| Enge, A | 1 |
| Tan, TL | 1 |
| Bixler, EO | 2 |
| Cadieux, RJ | 1 |
| Goodman, AL | 1 |
| Pinnock, CA | 2 |
| Fell, D | 2 |
| Hunt, PC | 1 |
| Miller, R | 1 |
| Smith, G | 1 |
| Fancourt, G | 1 |
| Castleden, M | 1 |
| Hughes, RR | 1 |
| Hart, DM | 1 |
| Laing, M | 1 |
| Thomas, D | 1 |
| Tipping, T | 1 |
| Halifax, R | 1 |
| Blogg, CE | 1 |
| Hollands, MA | 1 |
| Soldatos, CR | 1 |
3 reviews available for triazolam and Anxiety
| Article | Year |
|---|---|
Sleep laboratory studies of hypnotic drugs: efficacy and withdrawal effects.
Topics: Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Dose-Response Relationship, Drug; Fl | 1983 |
Rational basis for the use of sleeping pills.
Topics: Anxiety; Chronic Disease; Flurazepam; Humans; Hypnotics and Sedatives; Kinetics; Sleep; Sleep Initia | 1983 |
Behavioral side effects of benzodiazepine hypnotics.
Topics: Amnesia; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Flurazepam; Humans; Hypnotics and Sedatives; | 1985 |
19 trials available for triazolam and Anxiety
| Article | Year |
|---|---|
[Comprehensive evaluation of the effect of triazolam on amnesia during the preoperative period].
Topics: Adult; Amnesia; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Spinal; Anti-Anxiety Agents; | 2011 |
Anti-anxiety drugs reduce conflict-specific "theta"--a possible human anxiety-specific biomarker.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety; Biomarkers; Brain; Buspirone; Conflict, Psychologic | 2013 |
Zaleplon (Sonata) oral sedation for outpatient third molar extraction surgery.
Topics: Acetamides; Adolescent; Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesi | 2005 |
Decreasing pain and anxiety associated with patient-activated atrial shock: a placebo-controlled study of adjunctive sedation with oral triazolam.
Topics: Adjuvants, Anesthesia; Administration, Oral; Adult; Aged; Anxiety; Atrial Fibrillation; Conscious Se | 2006 |
Discriminative-stimulus effects of triazolam in women and men.
Topics: Anti-Anxiety Agents; Anxiety; Cognition; Discrimination, Psychological; Dose-Response Relationship, | 2006 |
Reinforcing effects of triazolam in sedative abusers: correlation of drug liking and self-administration measures.
Topics: Adult; Anxiety; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hypnotics and Sedativ | 1995 |
Quazepam versus triazolam in patients with sleep disorders: a double-blind study.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Double-Blind Method; Female; Human | 1993 |
Zolpidem and rebound insomnia--a double-blind, controlled polysomnographic study in chronic insomniac patients.
Topics: Adult; Aged; Anxiety; Chronic Disease; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; | 1994 |
Insomnia in generalized anxiety disorder: polysomnographic, psychometric and clinical investigations before, during and after therapy with a long- versus a short-half-life benzodiazepine (quazepam versus triazolam).
Topics: Adult; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Double-Blind Method; Female; Humans; Hypnotics | 1994 |
Premedication with sublingual triazolam compared with oral diazepam.
Topics: Administration, Oral; Administration, Sublingual; Adult; Age Factors; Aged; Anesthesia, Local; Anxie | 1993 |
Multi-clinic cross-over comparison of triazolam (Halcion) and placebo in the treatment of co-existing insomnia and anxiety in anxious out-patients.
Topics: Adolescent; Adult; Ambulatory Care; Anti-Anxiety Agents; Anxiety; Drug Evaluation; Female; Humans; M | 1977 |
Attenuation of anxiety in ambulatory oral surgery patients with oral triazolam.
Topics: Administration, Oral; Adolescent; Adult; Ambulatory Surgical Procedures; Anxiety; Double-Blind Metho | 1991 |
[Premedication with triazolam].
Topics: Adult; Anxiety; Blood Pressure; Depression; Depression, Chemical; Female; Flunitrazepam; Heart Rate; | 1990 |
Triazolam syndrome 10 years on.
Topics: Adult; Anxiety; Clinical Trials as Topic; Humans; Product Surveillance, Postmarketing; Syndrome; Tim | 1989 |
Effectiveness of triazolam, diazepam, and placebo as preanesthetic medications.
Topics: Adult; Anxiety; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Humans; Hypnotics a | 1989 |
Can a rapidly-eliminated hypnotic cause daytime anxiety?
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Body Weight; Dreams; Female; Humans; Hyp | 1989 |
A comparison of triazolam and diazepam as premedication agents for minor gynaecological surgery.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female | 1985 |
Lormetazepam or triazolam as night sedation before surgery.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Female; Humans; Lorazepam; Premedication; Slee | 1986 |
Triazolam premedication. A comparison with lorazepam and placebo in gynaecological patients.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anxiety; Dizziness; Double-Blind Method; Drug Evaluat | 1986 |
18 other studies available for triazolam and Anxiety
| Article | Year |
|---|---|
Testing an anxiety process biomarker: Generalisation from an auditory to a visual stimulus.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety; Auditory Perception; Biomarkers; Brain Waves; Buspi | 2016 |
Benzodiazepine and neuroactive steroid combinations in rats: anxiolytic-like and discriminative stimulus effects.
Topics: Anesthetics; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Clonazepam; Discrimination Lea | 2016 |
Evaluation of anxiolytic-like effects of some short-acting benzodiazepine hypnotics in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Azepines; Benzodiazepines; Diazepam; Hypnotics and Sedatives; | 2008 |
Anticonflict and reinforcing effects of triazolam + pregnanolone combinations in rhesus monkeys.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Conflict, Psychological; Dose-Response Rela | 2011 |
Reversal of triazolam tolerance and withdrawal-induced hyperlocomotor activity and anxiety by bupropion in mice.
Topics: Animals; Anxiety; Bupropion; Dopamine; Drug Tolerance; Female; Male; Mice; Motor Activity; Norepinep | 2005 |
Anxiety caused by a short-life hypnotic.
Topics: Anti-Anxiety Agents; Anxiety; Half-Life; Humans; Triazolam | 1982 |
Studies with modern hypnotics.
Topics: Anxiety; Benzodiazepines; Humans; Hypnotics and Sedatives; Sleep Initiation and Maintenance Disorder | 1984 |
Short acting benzodiazepines.
Topics: Amnesia; Anti-Anxiety Agents; Anxiety; Depression; Half-Life; Humans; Sleep Initiation and Maintenan | 1993 |
Daytime consumption of triazolam.
Topics: Adult; Aged; Anxiety; Circadian Rhythm; Drug Tolerance; Female; Humans; Male; Middle Aged; Self Medi | 1993 |
Pilot open-label study of triazolam in the treatment of insomnia following alcohol withdrawal.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Anxiety; Drug Evaluation; Female; Humans; Male; Middle Aged; | 1977 |
Two more benzodiazepines.
Topics: Anti-Anxiety Agents; Anxiety; Benzodiazepinones; Humans; Sleep Initiation and Maintenance Disorders; | 1979 |
Possible mechanism for adverse reactions to triazolam.
Topics: Alprazolam; Anxiety; Humans; Platelet Activating Factor; Receptors, GABA-A; Substance Withdrawal Syn | 1991 |
Relieving patient anxiety. A new approach.
Topics: Anxiety; Humans; Preanesthetic Medication; Tooth Extraction; Triazolam | 1991 |
Inadvertent general anaesthesia following oral premedication in the dental office. A case report.
Topics: Adolescent; Anesthesia, Dental; Anesthesia, General; Anxiety; Humans; Male; Preanesthetic Medication | 1989 |
[Clinical experiences with triazolam (Halcion)].
Topics: Adult; Anxiety; Depression; Female; Humans; Male; Middle Aged; Triazolam | 1989 |
Early morning insomnia, daytime anxiety, and organic mental disorder associated with triazolam.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Humans; Male; Sleep Initiation and Maintenance Disorders; Subst | 1985 |
The use of benzodiazepines with particular reference to the elderly.
Topics: Aged; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Diazepam; Humans; Infusions, Parenteral; Kinet | 1986 |
Triazolam premedication.
Topics: Anxiety; Humans; Preanesthetic Medication; Triazolam | 1987 |