triamterene has been researched along with Trypanosomiasis, African in 1 studies
Triamterene: A pteridinetriamine compound that inhibits SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS.
triamterene : Pteridine substituted at positions 2, 4 and 7 with amino groups and at position 6 with a phenyl group. A sodium channel blocker, it is used as a diuretic in the treatment of hypertension and oedema.
Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tulloch, LB | 1 |
| Martini, VP | 1 |
| Iulek, J | 1 |
| Huggan, JK | 1 |
| Lee, JH | 1 |
| Gibson, CL | 1 |
| Smith, TK | 1 |
| Suckling, CJ | 1 |
| Hunter, WN | 1 |
1 other study available for triamterene and Trypanosomiasis, African
| Article | Year |
|---|---|
Structure-based design of pteridine reductase inhibitors targeting African sleeping sickness and the leishmaniases.
Topics: Catalytic Domain; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Leishmania major | 2010 |