Page last updated: 2024-11-05

triamterene and Nephrotic Syndrome

triamterene has been researched along with Nephrotic Syndrome in 18 studies

Triamterene: A pteridinetriamine compound that inhibits SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS.
triamterene : Pteridine substituted at positions 2, 4 and 7 with amino groups and at position 6 with a phenyl group. A sodium channel blocker, it is used as a diuretic in the treatment of hypertension and oedema.

Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199014 (77.78)18.7374
1990's2 (11.11)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Essigke, D2
Bohnert, BN2
Janessa, A2
Wörn, M2
Omage, K2
Kalbacher, H1
Birkenfeld, AL2
Bugge, TH1
Szabo, R1
Artunc, F2
Schneider, JC1
Kalo, MZ1
Xiao, M1
Kong, L1
Hennenlotter, J1
Amend, B1
ANICHINI, M1
GARGANO, N1
BARTORELLI, C1
KATO, E1
OSAWA, S1
WAKASUGI, A1
KIRIU, Y1
ATO, T1
MITSUNO, K1
ITAZU, Y1
CONTI, M1
CATTANEO, G1
SPERBER, RJ1
DIRE, LB1
SINGER, MM1
FISCH, S1
DEGRAFF, AC1
Seller, RH1
Ramirez, O1
Brest, AN1
Tareeva, IE1
Poliantseva, LR1
Kutyrina, IM1
Haris, A1
Radó, JP2
Riechers, G1
Futerova, M1
Hanisch, M1
Ritter, W1
Kühn, K1
Garnett, ES1
Webber, CE1
Leiter, L1
Marosi, J1
Takó, J1
Anderton, JL1
Kincaid-Smith, P1
Reubi, FC1
Clancy, RL1
Stiel, JN1
Campanacci, D1
Bonomini, V1
Zucchelli, P2
Mioli, V1

Reviews

3 reviews available for triamterene and Nephrotic Syndrome

ArticleYear
Combinations of diuretics in the treatment of edema.
    American heart journal, 1970, Volume: 80, Issue:3

    Topics: Acetazolamide; Benzothiadiazines; Chlorthalidone; Diuretics; Edema; Ethacrynic Acid; Furosemide; Glu

1970
Diuretics. II. Clinical considerations.
    Drugs, 1971, Volume: 1, Issue:2

    Topics: Administration, Oral; Aminophylline; Ascites; Calcium; Carbohydrate Metabolism; Carbonic Anhydrase I

1971
Combination diuretic drug therapy.
    Cardiovascular clinics, 1971, Volume: 2, Issue:3

    Topics: Amiloride; Benzothiadiazines; Diet; Diuretics; Drug Therapy, Combination; Ethacrynic Acid; Furosemid

1971

Trials

3 trials available for triamterene and Nephrotic Syndrome

ArticleYear
Patterns of potassium wasting in response to stepwise combinations of diuretics in nephrotic syndrome.
    International journal of clinical pharmacology and therapeutics, 1999, Volume: 37, Issue:7

    Topics: Aged; Amiloride; Body Weight; Chlorthalidone; Diuresis; Diuretics; Drug Therapy, Combination; Female

1999
Effects of muzolimine and of a combination of hydrochlorothiazide/triamterene in healthy subjects and in nephrotic patients.
    Zeitschrift fur Kardiologie, 1985, Volume: 74 Suppl 2

    Topics: Adolescent; Adult; Aged; Body Weight; Creatinine; Drug Therapy, Combination; Electrolytes; Female; H

1985
High doses of spironolactone (Aldactone, SC-14266, Verospirone) alone and in combination with triamterene and-or diuretics in the treatment of refractory edema associated with secondary hyperaldosteronism.
    Endokrinologie, 1970, Volume: 57, Issue:1

    Topics: Adult; Aged; Body Weight; Chlorides; Clinical Trials as Topic; Clopamide; Creatinine; Diet, Sodium-R

1970

Other Studies

12 other studies available for triamterene and Nephrotic Syndrome

ArticleYear
Sodium retention in nephrotic syndrome is independent of the activation of the membrane-anchored serine protease prostasin (CAP1/PRSS8) and its enzymatic activity.
    Pflugers Archiv : European journal of physiology, 2022, Volume: 474, Issue:6

    Topics: Animals; Doxorubicin; Epithelial Sodium Channels; Mice; Nephrotic Syndrome; Serine Endopeptidases; S

2022
Experimental nephrotic syndrome leads to proteolytic activation of the epithelial Na
    American journal of physiology. Renal physiology, 2021, 10-01, Volume: 321, Issue:4

    Topics: Aldosterone; Animals; Antibiotics, Antineoplastic; Aprotinin; Doxorubicin; Epithelial Sodium Channel

2021
[Triamterene, a supposed aldosterone inhibitor. Diuretic activity in edematous subjects].
    La Presse medicale, 1963, Jan-19, Volume: 71

    Topics: Aldosterone; Diuretics; Edema; Heart Failure; Liver Cirrhosis; Mineralocorticoid Receptor Antagonist

1963
[CLINICAL TRIALS OF THE NEW ALDOSTERONE ANTAGONISTS OF A STEROID NATURE].
    [Chiryo] [Therapy], 1964, Volume: 46

    Topics: Adolescent; Chronic Disease; Diabetes Mellitus; Extremities; Familial Mediterranean Fever; Geriatric

1964
[2-4-7-TRIAMINO-6-PHENYLPTERIDINE (TRIAMTERENE) IN THE THERAPY OF EDEMA IN PREGNANCY].
    Minerva ginecologica, 1964, May-31, Volume: 16

    Topics: Albuminuria; Diuretics; Edema; Female; Humans; Nephrotic Syndrome; Pre-Eclampsia; Pregnancy; Pterins

1964
ETHACRYNIC ACID IN PATHOLOGICAL FLUID RETENTION.
    JAMA, 1965, Mar-01, Volume: 191

    Topics: Digoxin; Diuretics; Drug Therapy; Ethacrynic Acid; Geriatrics; Heart Failure; Humans; Hydrochlorothi

1965
Secondary aldosteronism in refractory edema.
    GP, 1967, Volume: 35, Issue:4

    Topics: Diuretics; Drug Synergism; Edema; Heart Failure; Humans; Hyperaldosteronism; Hypokalemia; Liver Cirr

1967
[Nephrotic syndrome: complications and general principles of treatment].
    Klinicheskaia meditsina, 1994, Volume: 72, Issue:2

    Topics: Diet, Sodium-Restricted; Dietary Fats; Dietary Proteins; Diuretics; Furosemide; Humans; Nephrotic Sy

1994
Changes in blood-volume produced by treatment in the nephrotic syndrome.
    Lancet (London, England), 1967, Oct-14, Volume: 2, Issue:7520

    Topics: Adolescent; Adult; Aged; Blood Volume; Blood Volume Determination; Body Weight; Child; Chlorothiazid

1967
Familial Mediterranean fever with amyloidosis.
    The Medical journal of Australia, 1968, Mar-23, Volume: 1, Issue:12

    Topics: Adult; Amyloid; Amyloidosis; Bendroflumethiazide; Blood Proteins; Diet Therapy; Electrophoresis; Eth

1968
[The use of triamterene in nephrotic syndromes].
    Minerva medica, 1963, Oct-10, Volume: 54, Issue:81 Suppl

    Topics: Adolescent; Adult; Humans; Nephrotic Syndrome; Triamterene

1963
[The clinical use of an association of hydrochlorothiazide and triamterene in nephrotic syndromes].
    Giornale di clinica medica, 1966, Volume: 47, Issue:11

    Topics: Adolescent; Adult; Aged; Amyloidosis; Child; Diabetic Nephropathies; Diuresis; Electrolytes; Female;

1966