triamterene has been researched along with Electrolytes in 42 studies
Triamterene: A pteridinetriamine compound that inhibits SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS.
triamterene : Pteridine substituted at positions 2, 4 and 7 with amino groups and at position 6 with a phenyl group. A sodium channel blocker, it is used as a diuretic in the treatment of hypertension and oedema.
Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a randomized double-blind, parallel group study, the effects of piretanide on serum electrolytes and on symptoms of congestive heart failure were compared with those of the combination piretanide plus triamterene in out-patients with mild to severe congestive heart failure." | 9.05 | The effects of piretanide, a potassium stable diuretic, on serum electrolytes in patients with congestive heart failure. ( Bückert, C; Freude, J; Jaeger, S; Pahnke, K; Verho, M, 1985) |
| " The renal and metabolic effects of the sulphamoylbenzoic acid diuretic, piretanide, have been studied, under controlled dietary conditions, in 39 patients with congestive cardiac failure." | 7.67 | Acute and long-term renal and metabolic effects of piretanide in congestive cardiac failure. ( Lant, AF; McNabb, WR; Noormohamed, FH, 1988) |
| "In the majority of hypertensive patients, treatment with 50 mg/d of hydrochlorothiazide does not cause marked hypokalemia or ventricular arrhythmias." | 5.07 | Diuretics, serum and intracellular electrolyte levels, and ventricular arrhythmias in hypertensive men. ( Black, DM; Cheitlin, MD; Fine, R; Hearst, N; Hulley, SB; Sebastian, A; Seeley, DG; Siegel, D, 1992) |
| "In a randomized double-blind, parallel group study, the effects of piretanide on serum electrolytes and on symptoms of congestive heart failure were compared with those of the combination piretanide plus triamterene in out-patients with mild to severe congestive heart failure." | 5.05 | The effects of piretanide, a potassium stable diuretic, on serum electrolytes in patients with congestive heart failure. ( Bückert, C; Freude, J; Jaeger, S; Pahnke, K; Verho, M, 1985) |
| " The renal and metabolic effects of the sulphamoylbenzoic acid diuretic, piretanide, have been studied, under controlled dietary conditions, in 39 patients with congestive cardiac failure." | 3.67 | Acute and long-term renal and metabolic effects of piretanide in congestive cardiac failure. ( Lant, AF; McNabb, WR; Noormohamed, FH, 1988) |
| " Thus, this long-term study provides additional evidence that diuretics have a flat dose-response curve with respect to their antihypertensive efficacy, whereas lower doses might cause less pronounced activation of counter-regulatory systems." | 2.67 | Long-term diuretic therapy: effects of dose reduction on antihypertensive efficacy and counterregulatory systems. ( Ripka, O; Weisser, B, 1992) |
| "Hydrochlorothiazide was assayed in 24-hour urine samples." | 2.66 | Comparative efficacy and bioequivalence of a brand-name and a generic triamterene-hydrochlorothiazide combination product. ( Cane, RC; Costello, K; Goodwin, P; Perkal, M; Sharoky, M; Tabatznik, B, 1989) |
| "The antihypertensive and biochemical effects of 25 mg hydrochlorothiazide alone or 50 mg hydrochlorothiazide alone or in combination with triamterene (either 37." | 2.66 | Antihypertensive and biochemical effects of different doses of hydrochlorothiazide alone or in combination with triamterene. ( Eisalo, A; Gordin, A; Kohvakka, A; Salo, H, 1986) |
| "Amiloride hydrochloride has now been recognized as a safe and effective potassium-sparing diuretic alternative to triamterene with a similar mechanism of pharmacologic activity." | 2.66 | Antihypertensive therapy with triamterene-hydrochlorothiazide vs amiloride-hydrochlorothiazide. Comparison of effects on urinary prostaglandin E2 excretion. ( Zawada, ET, 1986) |
| " A dose-response relationship has been established for the effect of amiloride in reducing fractional excretion of magnesium and potassium during frusemide diuresis in rats." | 2.37 | Effects of diuretics on the renal handling of magnesium. ( Counihan, TB; Devane, J; Ryan, MF; Ryan, MP, 1984) |
| "Behavioral performances of six baboons were tested during chronic oral dosing with diuretic (hydrochlorothiazide/triamterene), a calcium channel blocker (verapamil), and a combination of the two drugs." | 1.28 | Behavioral effects of chronic, orally administered diuretic and verapamil in baboons. ( Hienz, RD; Turkkan, JS, 1991) |
| " The interaction resulted in a small attenuation of the pharmacodynamic response to triamterene." | 1.27 | Pharmacokinetic drug interactions between triamterene and ranitidine in humans: alterations in renal and hepatic clearances and gastrointestinal absorption. ( Bochner, F; Muirhead, M; Somogyi, A, 1988) |
| "If triamterene was added to the bathing medium after the 45calcium exchange process had already reached a steady-state, no further increase in the extent of the intracellular calcium exchange was observed during an additional 30-min period of incubation." | 1.26 | [On the mechanism of the positive inotropic effect of triamterene on the myocardium (author's transl)]. ( Greeff, K; Noack, E, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (88.10) | 18.7374 |
| 1990's | 3 (7.14) | 18.2507 |
| 2000's | 1 (2.38) | 29.6817 |
| 2010's | 1 (2.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dalila, N | 1 |
| Brockmöller, J | 1 |
| Tzvetkov, MV | 1 |
| Schirmer, M | 1 |
| Haubrock, M | 1 |
| Vormfelde, SV | 1 |
| LAAS, H | 1 |
| BETZIEN, G | 1 |
| BRANCHRZ, H | 1 |
| PILIEGO, N | 1 |
| ROSSINI, P | 1 |
| DELZOTTI, G | 1 |
| AMERIO, A | 1 |
| MATARAZZO, C | 1 |
| LEONDEFF, I | 1 |
| GENTILELAROSA, C | 1 |
| MARANGONI, R | 2 |
| MELLONI, G | 1 |
| CASIROLA, G | 1 |
| CHERIE LIGNIERE, EL | 1 |
| POZZI, E | 1 |
| TAKAHASHI, H | 1 |
| MELLONI, GF | 1 |
| BARATTA, C | 1 |
| MERLO, L | 1 |
| ANTOGNETTI, R | 1 |
| KAGAWA, CM | 1 |
| BARAN, JS | 1 |
| KROL, WF | 1 |
| MOLTENI, A | 1 |
| BALDRATTI, G | 1 |
| SANTARATO, R | 1 |
| Ma, J | 1 |
| Albornoz, F | 1 |
| Yu, C | 1 |
| Byrne, DW | 1 |
| Vaughan, DE | 1 |
| Brown, NJ | 1 |
| Hofmann, LM | 1 |
| Steinberg, P | 1 |
| Rubio, MC | 1 |
| Ryan, MP | 2 |
| Devane, J | 2 |
| Ryan, MF | 1 |
| Counihan, TB | 1 |
| Sundberg, S | 1 |
| Salo, H | 2 |
| Gordin, A | 2 |
| Melamies, L | 1 |
| Lamminsivu, U | 1 |
| Nuotto, E | 1 |
| Keränen, A | 1 |
| Lammintausta, R | 1 |
| Anttila, M | 1 |
| Viinamäki, O | 1 |
| Angelkort, B | 1 |
| Letzel, H | 1 |
| Amery, A | 1 |
| Birkenhäger, W | 1 |
| Bogaert, M | 1 |
| Brixko, P | 1 |
| Bulpitt, C | 1 |
| Clement, D | 1 |
| De Leeuw, P | 1 |
| De Plaen, JF | 1 |
| Deruyttere, M | 1 |
| De Schaepdryver, A | 1 |
| Fagard, R | 1 |
| Forette, F | 1 |
| Forte, J | 1 |
| Hamdy, R | 1 |
| Hellemans, J | 1 |
| Henry, JF | 1 |
| Koistinen, A | 1 |
| Laaser, U | 1 |
| Laher, M | 1 |
| Leonetti, G | 1 |
| Lewis, P | 1 |
| Lund-Johansen, P | 1 |
| MacFarlane, J | 1 |
| Meurer, K | 1 |
| Miguel, P | 1 |
| Morris, J | 1 |
| Mutsers, A | 1 |
| Nissinen, A | 1 |
| O'Brien, E | 1 |
| Ohm, OJ | 1 |
| O'Malley, K | 1 |
| Pelemans, W | 1 |
| Perera, N | 1 |
| Tuomilehto, J | 1 |
| Verschueren, LJ | 1 |
| Willemse, P | 1 |
| Williams, B | 1 |
| Zanchetti, A | 1 |
| Ambrosioni, E | 1 |
| Tartagni, F | 1 |
| Lusa, AM | 1 |
| Bassein, L | 1 |
| Magnani, B | 1 |
| Greeff, K | 1 |
| Noack, E | 1 |
| Thompson, EJ | 1 |
| Torres, E | 1 |
| Grosberg, SJ | 1 |
| Martinez-Maldonado, M | 1 |
| Weisser, B | 1 |
| Ripka, O | 1 |
| Siegel, D | 1 |
| Hulley, SB | 1 |
| Black, DM | 1 |
| Cheitlin, MD | 1 |
| Sebastian, A | 1 |
| Seeley, DG | 1 |
| Hearst, N | 1 |
| Fine, R | 1 |
| Turkkan, JS | 1 |
| Hienz, RD | 1 |
| Sharoky, M | 1 |
| Perkal, M | 1 |
| Tabatznik, B | 1 |
| Cane, RC | 1 |
| Costello, K | 1 |
| Goodwin, P | 1 |
| McNabb, WR | 1 |
| Noormohamed, FH | 1 |
| Lant, AF | 1 |
| Muirhead, M | 1 |
| Bochner, F | 1 |
| Somogyi, A | 1 |
| Kohvakka, A | 1 |
| Eisalo, A | 1 |
| Zawada, ET | 1 |
| Verho, M | 1 |
| Bückert, C | 1 |
| Freude, J | 1 |
| Jaeger, S | 1 |
| Pahnke, K | 1 |
| Riechers, G | 1 |
| Futerova, M | 1 |
| Hanisch, M | 1 |
| Ritter, W | 1 |
| Kühn, K | 1 |
| von Bruchhausen, F | 1 |
| Bartelheimer, HK | 1 |
| Heller, J | 1 |
| Tata, PS | 1 |
| Sidorenko, BA | 1 |
| Kharchenko, VI | 1 |
| Titov, VN | 1 |
| Lotova, EV | 1 |
| Mel'nichenko, GA | 1 |
| Azzi, E | 1 |
| Perraro, F | 1 |
| Cruz, J | 1 |
| Mattar, E | 1 |
| Cruz, HM | 1 |
| Păunescu-Podanu, A | 1 |
| Demirian, H | 1 |
| Ionitã, C | 1 |
| Georgescu, D | 1 |
| Tarachiu, A | 1 |
| Anghel, R | 1 |
| Rubingher, L | 1 |
| Maragliano, G | 1 |
| Clausen, E | 1 |
| Funder, J | 1 |
| Nielsen, OE | 1 |
| Trap-Jensen, J | 1 |
| Vejlsgård, V | 1 |
| Wieth, JO | 1 |
| Niall, JF | 1 |
| Pak POY, RK | 1 |
| Mioli, V | 1 |
| Zucchelli, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000525] | Phase 3 | 233 participants (Actual) | Interventional | 1986-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for triamterene and Electrolytes
| Article | Year |
|---|---|
Effects of diuretics on the renal handling of magnesium.
Topics: Amiloride; Animals; Diuretics; Drug Interactions; Electrolytes; Furosemide; Glomerular Filtration Ra | 1984 |
16 trials available for triamterene and Electrolytes
| Article | Year |
|---|---|
Impact of mineralocorticoid receptor polymorphisms on urinary electrolyte excretion with and without diuretic drugs.
Topics: Adolescent; Adult; Bumetanide; Cross-Over Studies; Diuretics; Electrolytes; Furosemide; Genetic Asso | 2015 |
Differing effects of mineralocorticoid receptor-dependent and -independent potassium-sparing diuretics on fibrinolytic balance.
Topics: Adult; Cross-Over Studies; Diuretics; Double-Blind Method; Electrolytes; Female; Fibrinolysis; Hemod | 2005 |
Effect of low dose diuretics on plasma and blood cell electrolytes, plasma uric acid and blood glucose.
Topics: Adult; Amiloride; Blood Glucose; Clinical Trials as Topic; Diuretics; Double-Blind Method; Electroly | 1982 |
Response of renin, aldosterone and antidiuretic hormone to furosemide and furosemide-triamterene combination.
Topics: Adult; Aldosterone; Drug Combinations; Electrolytes; Furosemide; Humans; Male; Random Allocation; Re | 1980 |
[Clinical aspects and therapy of hydropic heart insufficiency. Results of a multicenter field study].
Topics: Adult; Aged; Clinical Trials as Topic; Coronary Disease; Drug Therapy, Combination; Edema, Cardiac; | 1981 |
Antihypertensive therapy in patients above age 60 with systolic hypertension. A progress report of the European Working Party on High Blood Pressure in the Elderly (EWPHE).
Topics: Aged; Blood Glucose; Blood Pressure; Creatinine; Drug Therapy, Combination; Electrolytes; Female; Hu | 1982 |
Effects of tienilic acid used alone and in association with triamterene or amiloride on urinary excretion of electrolytes.
Topics: Amiloride; Diuresis; Drug Interactions; Electrolytes; Female; Glycolates; Humans; Male; Middle Aged; | 1981 |
Effect of triamterene on potassium excretion in cirrhotic patients receiving furosemide.
Topics: Chlorides; Clinical Trials as Topic; Drug Therapy, Combination; Electrolytes; Female; Furosemide; Hu | 1977 |
Long-term diuretic therapy: effects of dose reduction on antihypertensive efficacy and counterregulatory systems.
Topics: Aldosterone; Benzothiadiazines; Blood Pressure; Body Weight; Diuretics; Dose-Response Relationship, | 1992 |
Diuretics, serum and intracellular electrolyte levels, and ventricular arrhythmias in hypertensive men.
Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Chlorthalidone; Double-Blind Method; Electrocardi | 1992 |
Comparative efficacy and bioequivalence of a brand-name and a generic triamterene-hydrochlorothiazide combination product.
Topics: Adolescent; Adult; Aged; Blood Pressure; Chromatography, High Pressure Liquid; Drug Combinations; El | 1989 |
Antihypertensive and biochemical effects of different doses of hydrochlorothiazide alone or in combination with triamterene.
Topics: Adult; Aged; Blood Glucose; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy | 1986 |
Antihypertensive therapy with triamterene-hydrochlorothiazide vs amiloride-hydrochlorothiazide. Comparison of effects on urinary prostaglandin E2 excretion.
Topics: Amiloride; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Dinoprostone; Drug Com | 1986 |
The effects of piretanide, a potassium stable diuretic, on serum electrolytes in patients with congestive heart failure.
Topics: Adult; Aged; Blood Pressure; Body Weight; Clinical Trials as Topic; Diuretics; Double-Blind Method; | 1985 |
Effects of muzolimine and of a combination of hydrochlorothiazide/triamterene in healthy subjects and in nephrotic patients.
Topics: Adolescent; Adult; Aged; Body Weight; Creatinine; Drug Therapy, Combination; Electrolytes; Female; H | 1985 |
[Controlled clinical trial of the association of furosemide and triamterene].
Topics: Ascites; Diuresis; Edema; Electrolytes; Furosemide; Heart Failure; Humans; Liver Cirrhosis; Triamter | 1971 |
25 other studies available for triamterene and Electrolytes
| Article | Year |
|---|---|
[ON THE ANTIHYPERTENSIVE EFFECT OF THE SUBSTANCES ISOBUTYLHYDROCHLOROTHIAZIDE, SPIRONOLACTONE AND TRIAMTERENE ACTING ON ELECTROLYTES].
Topics: Antihypertensive Agents; Diuretics; Electrolytes; Geriatrics; Humans; Hydrochlorothiazide; Hypertens | 1963 |
[DIURESIS, ELECTROLYTES AND ALDOSTERONE AFTER TRIAMTERENE: FINDINGS IN THE SO-CALLED "REFRACTORY EDEMAS" OF PATIENTS WITH HEART DISEASE AND LIVER CIRRHOSIS].
Topics: Aldosterone; Ascites; Diuresis; Diuretics; Edema; Electrolytes; Heart Failure; Liver Cirrhosis; Pter | 1963 |
[CHANGES OF THE ALDOSTERONE EFFECT INDUCED BY SPIRONOLACTONE AND TRIAMTERENE. STUDY OF THE POSSIBLE MECHANISM OF ACTION].
Topics: Aldosterone; Diuretics; Electrolytes; Erythrocytes; Pharmacology; Pterins; Rats; Research; Spironola | 1963 |
[OBSERVATIONS ON ELECTROLYTE CHANGES IN CONGESTIVE HEART FAILURE DURING CARDIOKINETIC OR DEPLETIVE TREATMENT].
Topics: Aortic Diseases; Arteriosclerosis; Blood Chemical Analysis; Diuretics; Electrolytes; Heart Failure; | 1964 |
[INFLUENCE OF TRIAMTERENE ON SALIDIURESIS AND RENAL HEMODYNAMICS OF INDIVIDUALS WITH ASCITOGENIC HEPATIC CIRRHOSIS IN TREATMENT WITH HYDROCHLOROTHIAZIDE].
Topics: Ascites; Blood Circulation; Diuresis; Diuretics; Electrolytes; Hemodynamics; Hydrochlorothiazide; Ki | 1963 |
[ON CHANGES IN BLOOD VESSEL WALL ELECTROLYTES AND THE ADRENAL CORTEX IN EXPERIMENTAL HYPERTENSION].
Topics: Adrenal Cortex; Aldosterone; Aorta; Blood Pressure Determination; Carbon Tetrachloride Poisoning; Co | 1964 |
[ON MODIFICATIONS OF PLASMA AND URINARY ELECTROLYTES IN ASCITOGENIC HEPATIC CIRRHOSIS IN TREATMENT WITH TRIAMTERENE ALONE AND ASSOCIATED WITH HYDROCHLOROTHIAZIDE AND WITH SPIRONOLACTONE].
Topics: Ascites; Biomedical Research; Chlorides; Electrolytes; Geriatrics; Humans; Hydrochlorothiazide; Live | 1964 |
URINARY ELECTROLYTE EFFECTS OF OUABAIN AND OUABAGENIN IN ADRENALECTOMIZED RATS.
Topics: Adrenalectomy; Chlorides; Diuresis; Diuretics; Electrolytes; Natriuresis; Ouabain; Pharmacology; Pot | 1964 |
[ACTIVITY ON URINARY ELECTROLYTES OF VARIOUS TRIAMTERENE AND HYDROCHLOROTHIAZIDE ASSOCIATIONS].
Topics: Electrolytes; Hydrochlorothiazide; Potassium; Rats; Research; Sodium; Sodium, Dietary; Triamterene; | 1965 |
Azido pyrimidine diuretics (SC-16102, SC-16100): ADH antagonism assay in the rat.
Topics: Animals; Diuretics; Electrolytes; Furosemide; Hydrochlorothiazide; Male; Prednisone; Pyrimidines; Ra | 1967 |
Effect of triamterene on tyrosine hydroxylase activity.
Topics: Adrenal Glands; Animals; Biopterins; Catecholamines; Electrolytes; Hydroxylation; In Vitro Technique | 1984 |
The effects of amiloride and triamterene on urinary magnesium excretion in conscious saline-loaded rats.
Topics: Amiloride; Animals; Electrolytes; Furosemide; Magnesium; Male; Pyrazines; Rats; Triamterene | 1981 |
[On the mechanism of the positive inotropic effect of triamterene on the myocardium (author's transl)].
Topics: Adrenergic beta-Antagonists; Animals; Calcium; Drug Interactions; Electrolytes; Guinea Pigs; In Vitr | 1979 |
Behavioral effects of chronic, orally administered diuretic and verapamil in baboons.
Topics: Animals; Behavior, Animal; Blood Pressure; Color Perception; Conditioning, Operant; Desoxycorticoste | 1991 |
Acute and long-term renal and metabolic effects of piretanide in congestive cardiac failure.
Topics: Adult; Aged; Diuretics; Electrolytes; Female; Furosemide; Heart Failure; Humans; Kidney; Male; Middl | 1988 |
Pharmacokinetic drug interactions between triamterene and ranitidine in humans: alterations in renal and hepatic clearances and gastrointestinal absorption.
Topics: Adult; Drug Interactions; Electrolytes; Humans; Intestinal Absorption; Kidney; Liver; Male; Metaboli | 1988 |
[Changes in electrolyte movements induced by diuretics in isolated adipose tissue].
Topics: Adipose Tissue; Biological Transport; Depression, Chemical; Diuretics; Electrolytes; Ethacrynic Acid | 1968 |
The influence of chlorthalidone, etozoline and triamterene on electrolyte and urea concentration gradients in the rat kidney.
Topics: Acetates; Animals; Carbonic Anhydrase Inhibitors; Chlorthalidone; Diuretics; Electrolytes; Female; K | 1968 |
[Comparison of the effectiveness and mechanism of action of the saluretic preparations triamterene and hypothiazide and their combination (triampur) in circulatory insufficiency].
Topics: Acid-Base Equilibrium; Adult; Aged; Arteriosclerosis; Circadian Rhythm; Coronary Disease; Creatinine | 1973 |
[Triamterene-frusemide combination in edematous patients].
Topics: Adult; Ascites; Body Weight; Diuresis; Diuretics; Drug Synergism; Edema; Electrolytes; Female; Furos | 1970 |
[Clinical and biochemical study of the therapeutic effect of the diuretic triamterene in ascitogenic cirrhosis].
Topics: Adrenal Cortex Hormones; Ascites; Diuresis; Electrolytes; Humans; Hydrochlorothiazide; Liver Cirrhos | 1968 |
[The use of triamterene in gestosis of the 3rd. trimester].
Topics: Animals; Cricetinae; Diuresis; Electrolytes; Female; Humans; Pre-Eclampsia; Pregnancy; Triamterene | 1969 |
[Effect of trichlormethiazide and triamterene on blood pressure, serum electrolytes and erythrocyte sodium].
Topics: Electrolytes; Erythrocytes; Female; Humans; Hypertension; Male; Potassium Chloride; Sodium; Triamter | 1966 |
Studies in familial hypokalaemic periodic paralysis.
Topics: Adult; Aldosterone; Blood Chemical Analysis; Chlorides; Diet, Sodium-Restricted; Diuresis; Electroly | 1966 |
[The clinical use of an association of hydrochlorothiazide and triamterene in nephrotic syndromes].
Topics: Adolescent; Adult; Aged; Amyloidosis; Child; Diabetic Nephropathies; Diuresis; Electrolytes; Female; | 1966 |