triamterene has been researched along with Aging in 6 studies
Triamterene: A pteridinetriamine compound that inhibits SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS.
triamterene : Pteridine substituted at positions 2, 4 and 7 with amino groups and at position 6 with a phenyl group. A sodium channel blocker, it is used as a diuretic in the treatment of hypertension and oedema.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study we compared the absorption and disposition of two commonly used combination formulations of hydrochlorothiazide and triamterene (Dyazide and Maxzide) in 48 patients with essential hypertension after dosing with each formulation to steady state." | 3.67 | Absorption and disposition of two combination formulations of hydrochlorothiazide and triamterene: influence of age and renal function. ( Benet, LZ; Blume, C; Clark, TS; Lin, E; Thornhill, MD; Upton, RA; Williams, RL, 1986) |
| " Furthermore, the pharmacodynamic action of diuretics was not significantly altered in the elderly." | 1.30 | Renal handling of drugs in the healthy elderly. Creatinine clearance underestimates renal function and pharmacokinetics remain virtually unchanged. ( Bischoff, I; Block, S; Fliser, D; Hanses, A; Joest, M; Mutschler, E; Ritz, E, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amery, A | 2 |
| Birkenhäger, W | 2 |
| Bulpitt, C | 2 |
| Clement, D | 2 |
| Deruyttere, M | 2 |
| De Schaepdryver, A | 2 |
| Dollery, C | 2 |
| Fagard, R | 2 |
| Forette, F | 2 |
| Forte, J | 2 |
| Hamdy, R | 1 |
| Leonetti, G | 1 |
| Lund-Johansen, P | 2 |
| MacFarlane, JP | 1 |
| Mutsers, A | 2 |
| O'Malley, K | 1 |
| Tuomilehto, J | 2 |
| Fliser, D | 1 |
| Bischoff, I | 1 |
| Hanses, A | 1 |
| Block, S | 1 |
| Joest, M | 1 |
| Ritz, E | 1 |
| Mutschler, E | 1 |
| Louis, WJ | 1 |
| Mander, AG | 1 |
| Dawson, M | 1 |
| O'Callaghan, C | 1 |
| Conway, EL | 1 |
| Berthaux, P | 1 |
| Boel, A | 1 |
| Brixko, P | 1 |
| De Padua, F | 1 |
| Henry, JF | 1 |
| Hellemans, J | 1 |
| Koistinen, A | 1 |
| Laaser, U | 1 |
| MacFarlane, J | 1 |
| Miguel, P | 1 |
| Nissinen, A | 1 |
| Ohm, OT | 1 |
| Pelemans, W | 1 |
| Suchett-Kaye, AI | 1 |
| Willems, J | 1 |
| Willemse, P | 1 |
| Djian, J | 1 |
| Roy, M | 1 |
| Forette, B | 1 |
| Lekieffre, J | 1 |
| Luccioni, R | 1 |
| Williams, RL | 1 |
| Thornhill, MD | 1 |
| Upton, RA | 1 |
| Blume, C | 1 |
| Clark, TS | 1 |
| Lin, E | 1 |
| Benet, LZ | 1 |
4 trials available for triamterene and Aging
| Article | Year |
|---|---|
Influence of anti-hypertensive therapy on serum cholesterol in elderly hypertensive patients. Results of trial by the European Working Party on High blood pressure in the Elderly (EWPHE).
Topics: Aged; Aging; Blood Pressure; Cholesterol; Clinical Trials as Topic; Europe; Female; Follow-Up Studie | 1982 |
Use of computerized neuropsychological tests (CANTAB) to assess cognitive effects of antihypertensive drugs in the elderly. Cambridge Neuropsychological Test Automated Battery.
Topics: Aged; Aging; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cogniti | 1999 |
Antihypertensive therapy in patients above age 60 years (Fourth Interim report of the European Working Party on High Blood pressure in Elderly: EWPHE).
Topics: Aged; Aging; Blood Glucose; Blood Pressure; Body Weight; Clinical Trials as Topic; Creatinine; Doubl | 1978 |
Efficacy and tolerance of sustained-release diltiazem 300 mg and a diuretic in the elderly.
Topics: Aged; Aging; Blood Pressure; Delayed-Action Preparations; Diltiazem; Drug Tolerance; Female; Heart R | 1990 |
2 other studies available for triamterene and Aging
| Article | Year |
|---|---|
Renal handling of drugs in the healthy elderly. Creatinine clearance underestimates renal function and pharmacokinetics remain virtually unchanged.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Atenolol; Creatinine; Diuretics; Female; Glomerular | 1999 |
Absorption and disposition of two combination formulations of hydrochlorothiazide and triamterene: influence of age and renal function.
Topics: Absorption; Adult; Aged; Aging; Biological Availability; Creatinine; Humans; Hydrochlorothiazide; Hy | 1986 |