triacetoneamine-n-oxyl and Carcinoma

triacetoneamine-n-oxyl has been researched along with Carcinoma* in 1 studies

Other Studies

1 other study(ies) available for triacetoneamine-n-oxyl and Carcinoma

Article	Year
[Experiment to potentiate the effect of cyclophosphamide combined with tempidon and caffeine in leukemia L1210 and Lewis hepatic carcinoma]. Eksperimentalna meditsina i morfologiia, 1978, Volume: 17, Issue:1 The authors carried out experiments on mice DBA/2 and BDF1 with leucosis L1210 and lung carcinoma of Lewis and found that psycotropic preparations tempidone and caffeine did not manifest antitumorous effect and toxicity after the used doses and scheme of treatment. Tempidone enhanced antitumorous action of small and mean doses of cyclophosphamide in mice with leucosis L1210. In the triple combination (tempidone, caffeine and cycl phosamide) the caffeine enhanced this action of tempidone without raising toxicity in mice with leucosis L1210, but not in mice with lung carcinoma of Lewis. Topics: Animals; Caffeine; Carcinoma; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Female; Leukemia L1210; Liver Neoplasms; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Piperidines; Piperidones; Psychotropic Drugs; Tosyl Compounds; Triacetoneamine-N-Oxyl	1978

Article

Year

[Experiment to potentiate the effect of cyclophosphamide combined with tempidon and caffeine in leukemia L1210 and Lewis hepatic carcinoma].

Eksperimentalna meditsina i morfologiia, 1978, Volume: 17, Issue:1

The authors carried out experiments on mice DBA/2 and BDF1 with leucosis L1210 and lung carcinoma of Lewis and found that psycotropic preparations tempidone and caffeine did not manifest antitumorous effect and toxicity after the used doses and scheme of treatment. Tempidone enhanced antitumorous action of small and mean doses of cyclophosphamide in mice with leucosis L1210. In the triple combination (tempidone, caffeine and cycl phosamide) the caffeine enhanced this action of tempidone without raising toxicity in mice with leucosis L1210, but not in mice with lung carcinoma of Lewis.

Topics: Animals; Caffeine; Carcinoma; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Female; Leukemia L1210; Liver Neoplasms; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Piperidines; Piperidones; Psychotropic Drugs; Tosyl Compounds; Triacetoneamine-N-Oxyl

1978