tretinoin and Retinal-Telangiectasis

To investigate the clinical study of intravitreal injection of anti-VEGF drugs combined with intravitreal injection of tretinoin for the treatment of Coats disease.. The medical records of 90 patients (120 eyes) with Coats disease admitted to our hospital from April 2010 to June 2021 were selected as retrospective study subjects and divided into control and treatment groups according to the numerical table method. There were 45 cases and 60 eyes in each group. Among them, intravitreal tretinoin drug was injected into the control group, and anti-VEGF drug was injected into the vitreous sclera of the treatment group on the basis of the control group.. Before treatment, the differences in visual acuity changes between the two groups were not statistically significant (. Intravitreal injection of anti-VEGF drugs combined with tretinoin injection can significantly improve the clinical efficacy of patients with Coats disease and improve visual acuity and central retinal thickness, which has certain reference value for the clinical treatment of Coats disease.

Topics: Angiogenesis Inhibitors; Humans; Intravitreal Injections; Retinal Telangiectasis; Retrospective Studies; Treatment Outcome; Tretinoin; Triamcinolone Acetonide