tretinoin and Mononeuropathies

tretinoin has been researched along with Mononeuropathies* in 1 studies

Reviews

1 review(s) available for tretinoin and Mononeuropathies

ArticleYear
All-trans retinoic acid-induced focal myositis, synovitis, and mononeuritis.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2009, Volume: 15, Issue:7

    All-trans retinoic acid has revolutionized the treatment of acute promyelocytic leukemia, but this therapy is often complicated by the all-trans retinoic acid syndrome. Here we report a patient with newly diagnosed acute promyelocytic leukemia who developed acute focal myositis, synovitis, and possible vasculitis, after receiving all-trans retinoic acid therapy. We review the existing literature on this rare clinical entity, all-trans retinoic acid-induced myositis. This condition can manifest as fever, myalgia, arthralgia, and Sweet syndrome, accompanied by distinct magnetic resonance findings involving the lower extremity musculature. Treatment consists of discontinuation of the offending drug and often high dose corticosteroids.

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Female; Humans; Leukemia, Promyelocytic, Acute; Middle Aged; Mononeuropathies; Myositis; Synovitis; Treatment Outcome; Tretinoin; Withholding Treatment

2009