tretinoin has been researched along with Adenoma--Sweat-Gland* in 2 studies
2 other study(ies) available for tretinoin and Adenoma--Sweat-Gland
Article | Year |
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Malignant eccrine poroma and isotretinoin.
Topics: Adenoma, Sweat Gland; Female; Humans; Isotretinoin; Middle Aged; Tretinoin | 1984 |
A malignant eccrine poroma responds to isotretinoin (13-cis-retinoic acid).
In treating a patient with a malignant eccrine poroma, in-vitro studies suggested resistance to dactinomycin and doxorubicin. A trial of weekly 5-fluorouracil produced no response. Likewise, a cycle of cisplatinum and cytarabine was associated with continued progression of the disease. Use of 13-cis retinoic acid induced a partial remission that lasted for 8 weeks with minimal toxicity. The mechanism of action is not known, but local tumor necrosis with sparing of the adjacent normal tissue suggests high specificity. Topics: Adenoma, Sweat Gland; Antineoplastic Agents; Drug Therapy, Combination; Humans; Isotretinoin; Lung Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary; Sweat Gland Neoplasms; Thigh; Tretinoin | 1983 |